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Conserved domains on  [gi|1957510811|ref|WP_200906062|]
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MULTISPECIES: BRO family protein [Aeromonas]

Protein Classification

Bro-N domain-containing protein( domain architecture ID 11466490)

Bro-N domain-containing protein may bind DNA to influence host DNA replication and/or transcription; may function as an antirepressor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3617 COG3617
Prophage antirepressor [Mobilome: prophages, transposons];
1-107 3.11e-48

Prophage antirepressor [Mobilome: prophages, transposons];


:

Pssm-ID: 442835  Cd Length: 106  Bit Score: 151.59  E-value: 3.11e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1957510811   1 MSVIKFEGVKVRIVNVHGVPWFIAKDVCDALELTNPSQALKALDDDEKGVTLSYTLGGTQKMRTIAESGFYKLLARSRKA 80
Cdd:COG3617     5 ITVFNFEGHEVRTVEIDGEPWFVAKDVARALGYSNPSDALKHLDDDEKTKLELDTPGGPQEMLFISESGLYRLILRSRKP 84

                          90       100
                  ....*....|....*....|....*..
gi 1957510811  81 TtpgtlAHRFCNWVFREVIPAIRKTGA 107
Cdd:COG3617    85 E-----AKRFKRWVTDEVLPSIRKTGS 106
 
Name Accession Description Interval E-value
COG3617 COG3617
Prophage antirepressor [Mobilome: prophages, transposons];
1-107 3.11e-48

Prophage antirepressor [Mobilome: prophages, transposons];


Pssm-ID: 442835  Cd Length: 106  Bit Score: 151.59  E-value: 3.11e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1957510811   1 MSVIKFEGVKVRIVNVHGVPWFIAKDVCDALELTNPSQALKALDDDEKGVTLSYTLGGTQKMRTIAESGFYKLLARSRKA 80
Cdd:COG3617     5 ITVFNFEGHEVRTVEIDGEPWFVAKDVARALGYSNPSDALKHLDDDEKTKLELDTPGGPQEMLFISESGLYRLILRSRKP 84

                          90       100
                  ....*....|....*....|....*..
gi 1957510811  81 TtpgtlAHRFCNWVFREVIPAIRKTGA 107
Cdd:COG3617    85 E-----AKRFKRWVTDEVLPSIRKTGS 106
Bro-N smart01040
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 10-100 4.85e-32

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 214989  Cd Length: 89  Bit Score: 109.97  E-value: 4.85e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1957510811   10 KVRIVNVHGVPWFIAKDVCDALELTNPSQALKALDDDEKGV---TLSYTLGGTQKMRTIAESGFYKLLARSRKATtpgtl 86
Cdd:smart01040   1 KVRTVLIDGEPWFVAKDVARALGYSNPRDAIRKLDDDEKRVagtELLDTLGGKQEVRIISESGLYRLIMRSRKPE----- 75

                           90
                   ....*....|....
gi 1957510811   87 AHRFCNWVFREVIP 100
Cdd:smart01040  76 AKKFRRWVTDEVLP 89
Bro-N pfam02498
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 10-100 2.19e-18

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteriztic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 376797  Cd Length: 96  Bit Score: 75.47  E-value: 2.19e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1957510811  10 KVRIV-NVHGVPWFIAKDVCDALELTNPSQAL-KALDDDEK--------GVTLSYTLGGTQKMRTIAESGFYKLLARSRK 79
Cdd:pfam02498   1 EIRTVvDENGEPWFVAKDVAKALGYTNPNKAIkKHVDKANKkclnelvnTLDHEDGKNGHPKTVFINEAGLYLLIMRSDK 80

                          90       100
                  ....*....|....*....|.
gi 1957510811  80 ATtpgtlAHRFCNWVFREVIP 100
Cdd:pfam02498  81 PK-----AEEFRKWVTQEVLP 96
 
Name Accession Description Interval E-value
COG3617 COG3617
Prophage antirepressor [Mobilome: prophages, transposons];
1-107 3.11e-48

Prophage antirepressor [Mobilome: prophages, transposons];


Pssm-ID: 442835  Cd Length: 106  Bit Score: 151.59  E-value: 3.11e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1957510811   1 MSVIKFEGVKVRIVNVHGVPWFIAKDVCDALELTNPSQALKALDDDEKGVTLSYTLGGTQKMRTIAESGFYKLLARSRKA 80
Cdd:COG3617     5 ITVFNFEGHEVRTVEIDGEPWFVAKDVARALGYSNPSDALKHLDDDEKTKLELDTPGGPQEMLFISESGLYRLILRSRKP 84

                          90       100
                  ....*....|....*....|....*..
gi 1957510811  81 TtpgtlAHRFCNWVFREVIPAIRKTGA 107
Cdd:COG3617    85 E-----AKRFKRWVTDEVLPSIRKTGS 106
Bro-N smart01040
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 10-100 4.85e-32

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 214989  Cd Length: 89  Bit Score: 109.97  E-value: 4.85e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1957510811   10 KVRIVNVHGVPWFIAKDVCDALELTNPSQALKALDDDEKGV---TLSYTLGGTQKMRTIAESGFYKLLARSRKATtpgtl 86
Cdd:smart01040   1 KVRTVLIDGEPWFVAKDVARALGYSNPRDAIRKLDDDEKRVagtELLDTLGGKQEVRIISESGLYRLIMRSRKPE----- 75

                           90
                   ....*....|....
gi 1957510811   87 AHRFCNWVFREVIP 100
Cdd:smart01040  76 AKKFRRWVTDEVLP 89
Bro-N pfam02498
BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI ...
 10-100 2.19e-18

BRO family, N-terminal domain; This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteriztic invariant alanine, leucine, isoleucine motif of the ALI proteins.


Pssm-ID: 376797  Cd Length: 96  Bit Score: 75.47  E-value: 2.19e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1957510811  10 KVRIV-NVHGVPWFIAKDVCDALELTNPSQAL-KALDDDEK--------GVTLSYTLGGTQKMRTIAESGFYKLLARSRK 79
Cdd:pfam02498   1 EIRTVvDENGEPWFVAKDVAKALGYTNPNKAIkKHVDKANKkclnelvnTLDHEDGKNGHPKTVFINEAGLYLLIMRSDK 80

                          90       100
                  ....*....|....*....|.
gi 1957510811  80 ATtpgtlAHRFCNWVFREVIP 100
Cdd:pfam02498  81 PK-----AEEFRKWVTQEVLP 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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