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Conserved domains on  [gi|1937378103|ref|WP_195918440|]
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helix-turn-helix transcriptional regulator [Pediococcus acidilactici]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 10054599)

helix-turn-helix (HTH) domain-containing protein with an XRE (Xenobiotic Response Element) family HTH domain, binds DNA and may function as a transcriptional regulator

CATH:  1.10.10.10
Gene Ontology:  GO:0003677
PubMed:  15808743|2644244|8831795
SCOP:  4000362

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-66 1.16e-21

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


:

Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 85.28  E-value: 1.16e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937378103   1 MSFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLLFNEE 66
Cdd:COG1476     3 KKLGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
DUF1093 super family cl02185
Protein of unknown function (DUF1093); This family consists of several hypothetical bacterial ...
 95-197 1.64e-04

Protein of unknown function (DUF1093); This family consists of several hypothetical bacterial proteins of unknown function.


The actual alignment was detected with superfamily member COG5294:

Pssm-ID: 470488  Cd Length: 121  Bit Score: 40.38  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937378103  95 TFGLGGLIVLALVSIGILcLGYYKGIgtIDRFDPFLSYKVGYTKLPSEKEISPNNKATNGYWTAWFTDNTM---GNEwTK 171
Cdd:COG5294     3 KFIKIGIIVLIVLIFGGL-FLLKGPN--LDRFNPFVGKETYYVKITNDGKKLKTKDSGNGYGIYEYTLTAYdedGKE-KE 78

                          90       100
                  ....*....|....*....|....*.
gi 1937378103 172 LTLTTGLNPgVKDPYVMAYHKGSYVK 197
Cdd:COG5294    79 VTFTASKEL-RKGAYLKLYNKGKGVK 103
 
Name Accession Description Interval E-value
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-66 1.16e-21

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 85.28  E-value: 1.16e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937378103   1 MSFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLLFNEE 66
Cdd:COG1476     3 KKLGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 7-61 5.76e-17

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 72.59  E-value: 5.76e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKL 61
Cdd:cd00093     4 LKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-61 4.59e-16

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 70.24  E-value: 4.59e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103    7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKL 61
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 7-61 2.31e-15

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 68.34  E-value: 2.31e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKL 61
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 2-93 1.03e-09

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 55.24  E-value: 1.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937378103   2 SFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLLFNEEiamkkDKEPSLATQI 81
Cdd:PRK09706    5 TLGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDETEPTGKNLFALAKALQCSPTWLLFGDE-----DKQPTPPVPL 79

                          90
                  ....*....|..
gi 1937378103  82 DHDVKLKSRYRR 93
Cdd:PRK09706   80 NQPVELSEDQKE 91
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 5-81 4.36e-05

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 41.85  E-value: 4.36e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937378103   5 DDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLetlhALSQLFnisleKLLfneeiamkkDKEPSLATQI 81
Cdd:TIGR03830  68 PEIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSK----ALDKLL-----RLL---------DKHPELLEEL 126
YxeA COG5294
Uncharacterized conserved protein YxeA, DUF1093 family [Function unknown];
95-197 1.64e-04

Uncharacterized conserved protein YxeA, DUF1093 family [Function unknown];


Pssm-ID: 444097  Cd Length: 121  Bit Score: 40.38  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937378103  95 TFGLGGLIVLALVSIGILcLGYYKGIgtIDRFDPFLSYKVGYTKLPSEKEISPNNKATNGYWTAWFTDNTM---GNEwTK 171
Cdd:COG5294     3 KFIKIGIIVLIVLIFGGL-FLLKGPN--LDRFNPFVGKETYYVKITNDGKKLKTKDSGNGYGIYEYTLTAYdedGKE-KE 78

                          90       100
                  ....*....|....*....|....*.
gi 1937378103 172 LTLTTGLNPgVKDPYVMAYHKGSYVK 197
Cdd:COG5294    79 VTFTASKEL-RKGAYLKLYNKGKGVK 103
 
Name Accession Description Interval E-value
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-66 1.16e-21

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 85.28  E-value: 1.16e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937378103   1 MSFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLLFNEE 66
Cdd:COG1476     3 KKLGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-75 1.32e-18

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 77.73  E-value: 1.32e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103   1 MSFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLLFNEEIAMKKDKEP 75
Cdd:COG1396     6 KALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLS 80
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 7-61 5.76e-17

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 72.59  E-value: 5.76e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKL 61
Cdd:cd00093     4 LKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-61 4.59e-16

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 70.24  E-value: 4.59e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103    7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKL 61
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 7-61 2.31e-15

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 68.34  E-value: 2.31e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKL 61
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 3-59 5.93e-14

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 64.96  E-value: 5.93e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1937378103   3 FKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLE 59
Cdd:COG1813    13 YGERIREAREARGLSQEELAEKLGVSESTIRRIERGEATPSLDTLRKLEKALGISLA 69
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
5-53 7.75e-12

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 59.18  E-value: 7.75e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1937378103   5 DDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQL 53
Cdd:COG2944     9 EEIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAALKLLRLL 57
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 1-66 8.80e-11

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 56.95  E-value: 8.80e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937378103   1 MSFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLLFNEE 66
Cdd:COG3620    16 DTLGEALRLMRKELGLSQLPVAELVGVSQSDILRIESGKRDPTVSTLEKIAEALGKELSAVLVVDD 81
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 2-93 1.03e-09

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 55.24  E-value: 1.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937378103   2 SFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLLFNEEiamkkDKEPSLATQI 81
Cdd:PRK09706    5 TLGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDETEPTGKNLFALAKALQCSPTWLLFGDE-----DKQPTPPVPL 79

                          90
                  ....*....|..
gi 1937378103  82 DHDVKLKSRYRR 93
Cdd:PRK09706   80 NQPVELSEDQKE 91
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 7-62 1.04e-09

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 53.45  E-value: 1.04e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLL 62
Cdd:pfam12844   4 LRKAREERGLTQEELAERLGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWLL 59
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 7-59 5.75e-09

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 51.37  E-value: 5.75e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGK-NMPSLETLHALSQLFNISLE 59
Cdd:pfam13560   6 LRRLRERAGLSQEALARRLGVSRSTLSRLETGRrGRPSPAVVERLARALGVDGA 59
PHA01976 PHA01976
helix-turn-helix protein
 1-61 1.98e-06

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 44.18  E-value: 1.98e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1937378103   1 MSFKDDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKL 61
Cdd:PHA01976    1 MSFAIQLIKARNARAWSAPELSRRAGVRHSLIYDFEADKRLPNLKTLLRLADALGVTLDWL 61
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 15-75 2.56e-06

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 44.41  E-value: 2.56e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937378103  15 NLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKLL-----FNEEIAMKKDKEP 75
Cdd:COG3093    22 GLSQTELAKALGVSRQRISEILNGKRAITADTALRLARAFGTSAEFWLnlqaaYDLWLARQKAGEE 87
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 5-81 4.36e-05

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 41.85  E-value: 4.36e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937378103   5 DDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLetlhALSQLFnisleKLLfneeiamkkDKEPSLATQI 81
Cdd:TIGR03830  68 PEIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSK----ALDKLL-----RLL---------DKHPELLEEL 126
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 2-74 5.43e-05

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 43.96  E-value: 5.43e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1937378103   2 SFKDDIKTLRRQSNLTQEALAQKLH-----VTRQTVSTWETGKNMPSLETLHALSQLFNISlEKLLFNEEIAMKKDKE 74
Cdd:PRK13355    3 TFAERLKQAMKARGLKQEDLVHAAEargvkLGKSHISQYVSGKTGPRRDVLPFLAAILGVS-EDWLLGGESPADQESD 79
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 7-62 9.17e-05

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 39.45  E-value: 9.17e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNM-PSLETLHALSQLFNISLEKLL 62
Cdd:pfam13443   2 LRKLMADRGISKSDLARATGISRATLSRLRKGKPKrVSLDTLDKICDALGCQPGDLL 58
YxeA COG5294
Uncharacterized conserved protein YxeA, DUF1093 family [Function unknown];
95-197 1.64e-04

Uncharacterized conserved protein YxeA, DUF1093 family [Function unknown];


Pssm-ID: 444097  Cd Length: 121  Bit Score: 40.38  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937378103  95 TFGLGGLIVLALVSIGILcLGYYKGIgtIDRFDPFLSYKVGYTKLPSEKEISPNNKATNGYWTAWFTDNTM---GNEwTK 171
Cdd:COG5294     3 KFIKIGIIVLIVLIFGGL-FLLKGPN--LDRFNPFVGKETYYVKITNDGKKLKTKDSGNGYGIYEYTLTAYdedGKE-KE 78

                          90       100
                  ....*....|....*....|....*.
gi 1937378103 172 LTLTTGLNPgVKDPYVMAYHKGSYVK 197
Cdd:COG5294    79 VTFTASKEL-RKGAYLKLYNKGKGVK 103
PRK04140 PRK04140
transcriptional regulator;
5-75 7.97e-04

transcriptional regulator;


Pssm-ID: 235224 [Multi-domain]  Cd Length: 317  Bit Score: 39.84  E-value: 7.97e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937378103   5 DDIKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEK----LLFNEEIAMKKDKEP 75
Cdd:PRK04140  129 DVLREAREELGLSLGELASELGVSRRTISKYENGGMNASIEVAIKLEEILDVPLTKpidiLEKVRDDEVTPEDPE 203
COG1395 COG1395
Predicted transcriptional regulator [Transcription];
7-55 9.28e-04

Predicted transcriptional regulator [Transcription];


Pssm-ID: 441005 [Multi-domain]  Cd Length: 313  Bit Score: 39.82  E-value: 9.28e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFN 55
Cdd:COG1395   132 LRELREERGLSLGELASELGVSRRTISKYERGEMDASIEVALKLEEILG 180
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
7-90 1.65e-03

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 38.24  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISLEKlLFNEEiamKKDKEPSLATQIDHDVK 86
Cdd:PRK09943   12 LSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSE-FFSEP---EKPDEPQVVINQDDLIE 87


                  ....
gi 1937378103  87 LKSR 90
Cdd:PRK09943   88 MGSQ 91
PRK09726 PRK09726
type II toxin-antitoxin system antitoxin HipB;
7-58 2.47e-03

type II toxin-antitoxin system antitoxin HipB;


Pssm-ID: 182049  Cd Length: 88  Bit Score: 36.11  E-value: 2.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1937378103   7 IKTLRRQSNLTQEALAQKLHVTRQTVSTWETGKNMPSLETLHALSQLFNISL 58
Cdd:PRK09726   17 MKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSM 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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