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Conserved domains on  [gi|1887500686|ref|WP_182074508|]
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MULTISPECIES: YdgH/BhsA/McbA-like domain containing protein [unclassified Serratia (in: enterobacteria)]

Protein Classification

DUF1471 domain-containing protein( domain architecture ID 28000)

DUF1471 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YdgH_BhsA-like super family cl11507
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 1-85 8.54e-07

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


The actual alignment was detected with superfamily member PRK10259:

Pssm-ID: 448290  Cd Length: 86  Bit Score: 42.78  E-value: 8.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1887500686  1 MKNIKIFATAALLATASFATFAAELPTSQPAADAQKIGVVTVSGAANLSALESELASKAAASGASSYRIVAAGGQNKLYG 80
Cdd:PRK10259   1 MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADGASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSG 80


                 ....*
gi 1887500686 81 TAEIF 85
Cdd:PRK10259  81 TAVIY 85
 
Name Accession Description Interval E-value
PRK10259 PRK10259
hypothetical protein; Provisional
 1-85 8.54e-07

hypothetical protein; Provisional


Pssm-ID: 137782  Cd Length: 86  Bit Score: 42.78  E-value: 8.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1887500686  1 MKNIKIFATAALLATASFATFAAELPTSQPAADAQKIGVVTVSGAANLSALESELASKAAASGASSYRIVAAGGQNKLYG 80
Cdd:PRK10259   1 MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADGASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSG 80


                 ....*
gi 1887500686 81 TAEIF 85
Cdd:PRK10259  81 TAVIY 85
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 35-85 2.38e-05

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 37.89  E-value: 2.38e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 1887500686 35 QKIGVVTVSG-AANLSALESELASKAAASGASSYRIVAAGGQ--NKLYGTAEIF 85
Cdd:pfam07338  2 QPIGTVSVSGvFGSPSDAEAALSKKADAKGAKSYRIISADEPngGNWHGTAELY 55
 
Name Accession Description Interval E-value
PRK10259 PRK10259
hypothetical protein; Provisional
 1-85 8.54e-07

hypothetical protein; Provisional


Pssm-ID: 137782  Cd Length: 86  Bit Score: 42.78  E-value: 8.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1887500686  1 MKNIKIFATAALLATASFATFAAELPTSQPAADAQKIGVVTVSGAANLSALESELASKAAASGASSYRIVAAGGQNKLYG 80
Cdd:PRK10259   1 MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADGASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSG 80


                 ....*
gi 1887500686 81 TAEIF 85
Cdd:PRK10259  81 TAVIY 85
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 35-85 2.38e-05

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 37.89  E-value: 2.38e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 1887500686 35 QKIGVVTVSG-AANLSALESELASKAAASGASSYRIVAAGGQ--NKLYGTAEIF 85
Cdd:pfam07338  2 QPIGTVSVSGvFGSPSDAEAALSKKADAKGAKSYRIISADEPngGNWHGTAELY 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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