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Conserved domains on  [gi|1841573366|ref|WP_170913295|]
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sugar transferase, partial [Salmonella enterica]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10124 super family cl46974
putative UDP-glucose lipid carrier transferase; Provisional
 1-157 3.75e-132

putative UDP-glucose lipid carrier transferase; Provisional


The actual alignment was detected with superfamily member PRK10124:

Pssm-ID: 481314 [Multi-domain]  Cd Length: 463  Bit Score: 376.75  E-value: 3.75e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 80
Cdd:PRK10124  307 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 386

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841573366  81 NEQYRQLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAAY 157
Cdd:PRK10124  387 NEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY 463
 
Name Accession Description Interval E-value
PRK10124 PRK10124
putative UDP-glucose lipid carrier transferase; Provisional
 1-157 3.75e-132

putative UDP-glucose lipid carrier transferase; Provisional


Pssm-ID: 182254 [Multi-domain]  Cd Length: 463  Bit Score: 376.75  E-value: 3.75e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 80
Cdd:PRK10124  307 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 386

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841573366  81 NEQYRQLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAAY 157
Cdd:PRK10124  387 NEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY 463
WcaJ_sugtrans TIGR03023
Undecaprenyl-phosphate glucose phosphotransferase; This family of proteins encompasses the E. ...
 1-157 3.65e-125

Undecaprenyl-phosphate glucose phosphotransferase; This family of proteins encompasses the E. coli WcaJ protein involved in colanic acid biosynthesis, the Methylobacillus EpsB protein involved in methanolan biosynthesis, as well as the GumD protein involved in the biosynthesis of xanthan. All of these are closely related to the well-characterized WbaP (formerly RfbP) protein, which is the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose (NOTE: not glucose) to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. Colanic acid biosynthesis utilizes a glucose-undecaprenyl carrier, knockout of EpsB abolishes incorporation of UDP-glucose into the lipid phase, and the C-terminal portion of GumD has been shown to be responsible for the glucosyl-1-transferase activity.


Pssm-ID: 274396 [Multi-domain]  Cd Length: 450  Bit Score: 358.43  E-value: 3.65e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 80
Cdd:TIGR03023 294 VLFRQERYGLDGRPFMVYKFRSMRVHAEGDGVTQATRNDPRVTRVGAFLRRTSLDELPQFFNVLKGDMSIVGPRPHAVAH 373

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841573366  81 NEQYRQLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAAY 157
Cdd:TIGR03023 374 NEQYRKLIPGYMLRHKVKPGITGWAQVNGLRGETDTLEKMEKRVEYDLYYIENWSLWLDLKIILLTVFKGFVGKNAY 450
WcaJ COG2148
Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane ...
 1-156 2.47e-85

Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441751 [Multi-domain]  Cd Length: 322  Bit Score: 252.73  E-value: 2.47e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVM-ENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVA 79
Cdd:COG2148   173 VFFRQERVGRNGRPFTIYKFRTMRVDaEKLLGAVFKLKNDPRITRVGRFLRKTSLDELPQLWNVLKGDMSLVGPRPELPE 252

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841573366  80 HNEQYRQliEGYMLRHKMKPGITGWAQINGWRGETdtlekMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAA 156
Cdd:COG2148   253 EVELYEE--EEYRRRLLVKPGITGLAQVNGRNGET-----FEERVELDLYYIENWSLWLDLKILLKTVLVVLKGKGA 322
Bac_transf pfam02397
Bacterial sugar transferase; This Pfam family represents a conserved region from a number of ...
 1-151 5.57e-84

Bacterial sugar transferase; This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.


Pssm-ID: 460547 [Multi-domain]  Cd Length: 180  Bit Score: 244.19  E-value: 5.57e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 80
Cdd:pfam02397  35 VFFRQERVGKNGKPFTIYKFRTMVVDAEKRGPLFKLKNDPRITRVGRFLRKTSLDELPQLINVLKGDMSLVGPRPELPEF 114

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1841573366  81 neQYRQLIEGYMLRHKMKPGITGWAQINGWRGETDtlekMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGF 151
Cdd:pfam02397 115 --EYELYERDQRRRLSVKPGITGLAQVNGGRSELS----FEEKLELDLYYIENWSLWLDLKILLKTVKVVL 179
 
Name Accession Description Interval E-value
PRK10124 PRK10124
putative UDP-glucose lipid carrier transferase; Provisional
 1-157 3.75e-132

putative UDP-glucose lipid carrier transferase; Provisional


Pssm-ID: 182254 [Multi-domain]  Cd Length: 463  Bit Score: 376.75  E-value: 3.75e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 80
Cdd:PRK10124  307 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 386

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841573366  81 NEQYRQLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAAY 157
Cdd:PRK10124  387 NEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY 463
WcaJ_sugtrans TIGR03023
Undecaprenyl-phosphate glucose phosphotransferase; This family of proteins encompasses the E. ...
 1-157 3.65e-125

Undecaprenyl-phosphate glucose phosphotransferase; This family of proteins encompasses the E. coli WcaJ protein involved in colanic acid biosynthesis, the Methylobacillus EpsB protein involved in methanolan biosynthesis, as well as the GumD protein involved in the biosynthesis of xanthan. All of these are closely related to the well-characterized WbaP (formerly RfbP) protein, which is the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose (NOTE: not glucose) to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. Colanic acid biosynthesis utilizes a glucose-undecaprenyl carrier, knockout of EpsB abolishes incorporation of UDP-glucose into the lipid phase, and the C-terminal portion of GumD has been shown to be responsible for the glucosyl-1-transferase activity.


Pssm-ID: 274396 [Multi-domain]  Cd Length: 450  Bit Score: 358.43  E-value: 3.65e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 80
Cdd:TIGR03023 294 VLFRQERYGLDGRPFMVYKFRSMRVHAEGDGVTQATRNDPRVTRVGAFLRRTSLDELPQFFNVLKGDMSIVGPRPHAVAH 373

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841573366  81 NEQYRQLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAAY 157
Cdd:TIGR03023 374 NEQYRKLIPGYMLRHKVKPGITGWAQVNGLRGETDTLEKMEKRVEYDLYYIENWSLWLDLKIILLTVFKGFVGKNAY 450
EPS_sugtrans TIGR03025
exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Members of this family ...
 1-157 4.87e-103

exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Members of this family are generally found near other genes involved in the biosynthesis of a variety of exopolysaccharides. These proteins consist of two fused domains, an N-terminal hydrophobic domain of generally low conservation and a highly conserved C-terminal sugar transferase domain (pfam02397). Characterized and partially characterized members of this subfamily include Salmonella WbaP (originally RfbP), E. coli WcaJ, Methylobacillus EpsB, Xanthomonas GumD, Vibrio CpsA, Erwinia AmsG, Group B Streptococcus CpsE (originally CpsD), and Streptococcus suis Cps2E. Each of these is believed to act in transferring the sugar from, for instance, UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate as the first (priming) step in the synthesis of an oligosaccharide "block". This function is encoded in the C-terminal domain. The liposaccharide is believed to be subsequently transferred through a "flippase" function from the cytoplasmic to the periplasmic face of the inner membrane by the N-terminal domain. Certain closely related transferase enzymes, such as Sinorhizobium ExoY and Lactococcus EpsD, lack the N-terminal domain and are not found by this model.


Pssm-ID: 274398 [Multi-domain]  Cd Length: 445  Bit Score: 302.20  E-value: 4.87e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVM-ENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVA 79
Cdd:TIGR03025 292 VFFRQERVGLNGKPFTVYKFRSMRVDaEEGGGPVQATKNDPRITRVGRFLRRTSLDELPQLFNVLKGDMSLVGPRPERPA 371

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1841573366  80 HNEQYRQLIEGYMLRHKMKPGITGWAQINGwRGETDTlekMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAAY 157
Cdd:TIGR03025 372 EVEKYEQEIPGYMLRHKVKPGITGWAQVSG-RGETST---MEERVEYDLYYIENWSLWLDLKILLKTVKVVLTGKGAY 445
WcaJ COG2148
Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane ...
 1-156 2.47e-85

Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441751 [Multi-domain]  Cd Length: 322  Bit Score: 252.73  E-value: 2.47e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVM-ENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVA 79
Cdd:COG2148   173 VFFRQERVGRNGRPFTIYKFRTMRVDaEKLLGAVFKLKNDPRITRVGRFLRKTSLDELPQLWNVLKGDMSLVGPRPELPE 252

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841573366  80 HNEQYRQliEGYMLRHKMKPGITGWAQINGWRGETdtlekMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGFVNKAA 156
Cdd:COG2148   253 EVELYEE--EEYRRRLLVKPGITGLAQVNGRNGET-----FEERVELDLYYIENWSLWLDLKILLKTVLVVLKGKGA 322
Bac_transf pfam02397
Bacterial sugar transferase; This Pfam family represents a conserved region from a number of ...
 1-151 5.57e-84

Bacterial sugar transferase; This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.


Pssm-ID: 460547 [Multi-domain]  Cd Length: 180  Bit Score: 244.19  E-value: 5.57e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAH 80
Cdd:pfam02397  35 VFFRQERVGKNGKPFTIYKFRTMVVDAEKRGPLFKLKNDPRITRVGRFLRKTSLDELPQLINVLKGDMSLVGPRPELPEF 114

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1841573366  81 neQYRQLIEGYMLRHKMKPGITGWAQINGWRGETDtlekMEKRVEFDLEYIREWSIWFDIKIVFLTIFKGF 151
Cdd:pfam02397 115 --EYELYERDQRRRLSVKPGITGLAQVNGGRSELS----FEEKLELDLYYIENWSLWLDLKILLKTVKVVL 179
WbaP_sugtrans TIGR03022
Undecaprenyl-phosphate galactose phosphotransferase, WbaP; The WbaP (formerly RfbP) protein ...
 1-147 1.02e-44

Undecaprenyl-phosphate galactose phosphotransferase, WbaP; The WbaP (formerly RfbP) protein has been characterized as the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. This model includes the enterobacterial enzymes, where the function is presumed to be identical to the S. typhimurium enzyme as well as a somewhat broader group which are likely to catalyze the same or highly similar reactions based on a phylogenetic tree-building analysis of the broader sugar transferase family. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. The most likely heterogeneity would be in the precise nature of the sugar molecule transferred.


Pssm-ID: 274395 [Multi-domain]  Cd Length: 456  Bit Score: 152.13  E-value: 1.02e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMkVMENDKVVTQ----------------ATQNDPRVTRVGNFLRRTSLDELPQFINVL 64
Cdd:TIGR03022 293 AFYKQERVGRNGKLFKCYKFRTM-VMNSDQVLEEllaadpelraeweeyhKLRNDPRITRIGKFLRKTSLDELPQLWNVL 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366  65 TGGMSIVGPRPHAVAHNEQYRQLIEGYmlrHKMKPGITGWAQINGwRGETDtlekMEKRVEFDLEYIREWSIWFDIKIVF 144
Cdd:TIGR03022 372 KGDMSLVGPRPYLTSELSRYGEALELY---LRVRPGITGLWQVSG-RNETT----YDERVYLDVWYIKNWSLWLDIVILA 443


                  ...
gi 1841573366 145 LTI 147
Cdd:TIGR03022 444 KTI 446
EpsB_2 TIGR03013
sugar transferase, PEP-CTERM system associated; Members of this protein family belong to the ...
 1-147 1.41e-43

sugar transferase, PEP-CTERM system associated; Members of this protein family belong to the family of bacterial sugar transferases (pfam02397). Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria (notable exceptions appear to include Magnetococcus sp. MC-1 and Myxococcus xanthus DK 1622 ). These genes are generally found near one or more of the PrsK, PrsR or PrsT genes that have been related to the PEP-CTERM system by phylogenetic profiling methods. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species. These proteins are homologs of the EpsB protein found in Methylobacillus sp. strain 12S, which is also associated with a PEP-CTERM system, but of a distinct type. A name which appears attached to a number of genes (by transitive annotation) in this family is "undecaprenyl-phosphate galactose phosphotransferase", which comes from relatively distant characterized enterobacterial homologs, and is considerably more specific than warranted from the currently available evidence.


Pssm-ID: 274390 [Multi-domain]  Cd Length: 442  Bit Score: 149.07  E-value: 1.41e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   1 VIFRQTRYGMDGKPIKVWKFRSMKV-MENDKVVtQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVA 79
Cdd:TIGR03013 290 VLYRQERVGLNGRPFNLIKFRSMRAdAEKNGAV-WAQKDDPRVTRVGRFLRKTRIDELPQIFNVLRGDMSFVGPRPERPE 368

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366  80 HNEQYRQLIEGYMLRHKMKPGITGWAQINGWRG--ETDTLEKMekrvEFDLEYIREWSIWFDIKIVFLTI 147
Cdd:TIGR03013 369 FVEKLSEEIPYYNERHRVKPGITGWAQIKYPYGasVADAKEKL----RYDLYYIKNMSLLLDLIILIQTF 434
PRK15204 PRK15204
undecaprenyl-phosphate galactose phosphotransferase; Provisional
 2-147 6.46e-32

undecaprenyl-phosphate galactose phosphotransferase; Provisional


Pssm-ID: 185126 [Multi-domain]  Cd Length: 476  Bit Score: 118.18  E-value: 6.46e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366   2 IFRQTRYGMDGKPIKVWKFRSM---------KVMENDKVVTQ------ATQNDPRVTRVGNFLRRTSLDELPQFINVLTG 66
Cdd:PRK15204  314 IYGHQRVGRHGKLFPCYKFRSMvmnsqevlkELLANDPIARAewekdfKLKNDPRITAVGRFIRKTSLDELPQLFNVLKG 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841573366  67 GMSIVGPRPHAVAHNEQYRQLIEGYMLrhkMKPGITGWAQINGwRGETDtlekMEKRVEFDLEYIREWSIWFDIKIVFLT 146
Cdd:PRK15204  394 DMSLVGPRPIVSDELERYCDDVDYYLM---AKPGMTGLWQVSG-RNDVD----YDTRVYFDSWYVKNWTLWNDIAILFKT 465


                  .
gi 1841573366 147 I 147
Cdd:PRK15204  466 A 466
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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