|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
141-534 |
2.34e-78 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 252.99 E-value: 2.34e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 141 RGTLYLAVENLRSQPRTQWQTSIAEQNSRIPLELSL--LREQDLSPIERSKLladeeqmtsyinQQGSMILLAavDENTW 218
Cdd:PRK10604 44 KSSLYLMRSELREIPPRDWGKTLKEMDLNLSFDLRIepLSKYHLDPASQQRL------------REGEIVALD--DQYTF 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 219 L-RVEDN-----------ISYQTQLKLTTaIGGFFFLAISVAL--VMWIYPLWRDLKRLVKTANEFGQGVLSRRATTSRL 284
Cdd:PRK10604 110 LqRIPRShyvlavgpvpyLYYLHQMRLLD-IALLALIGLSLAFpvFLWMRPHWQDMLKLEAAAQRLGDGHLAERIHFDEG 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 285 SVVSQLSHSFNNMANNIEKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLEDediaLSQKEkyRQVIHSSIEDLDHLINQT 364
Cdd:PRK10604 189 SSLERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDN----LSAAE--SQALNRDIGQLEALIEEL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 365 LVLSRYNRITDIRHFSYCHFADNLVAEAEHFQLENPQLTLRVSVLDslRQQTIFVDNRALLRAVKNLLSNAARFAQQEIH 444
Cdd:PRK10604 263 LTYARLDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPH--QGDYGALDMRLMERVLDNLLNNALRYAHSRVR 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 445 LSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQITRWHQGKVRvkVNGSALGGACFE 524
Cdd:PRK10604 341 VSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVN--CDESELGGARFS 418
|
410
....*....|
gi 1841552669 525 LQWPKQISLP 534
Cdd:PRK10604 419 FSWPVWHNLP 428
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
243-530 |
1.04e-48 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 171.63 E-value: 1.04e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 243 LAISVALVMWIYPLWRDLKRLVKTANEFGQGVLSRRATTSRLSVVSQLSHSFNNMANNIEKLIASQRTLTNAVAHDLRTP 322
Cdd:COG0642 45 LLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTP 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 323 LYRLRFAFEMLEDEdiALSQKEKYRQVIHSSIEDLDHLINQTLVLSRYNRIT---DIRHFSYCHFADNLVAEAEHfQLEN 399
Cdd:COG0642 125 LTAIRGYLELLLEE--LDEEQREYLETILRSADRLLRLINDLLDLSRLEAGKlelEPEPVDLAELLEEVVELFRP-LAEE 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 400 PQLTLRVSVLDSLRqqTIFVDNRALLRAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPF 477
Cdd:COG0642 202 KGIELELDLPDDLP--TVRGDPDRLRQVLLNLLSNAIKYTPEggTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPF 279
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1841552669 478 TQVNNQERnsEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFELQWPKQ 530
Cdd:COG0642 280 FRTDPSRR--GGGTGLGLAIVKRIVELHGGTIEVE---SEPGkGTTFTVTLPLA 328
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
163-529 |
7.15e-48 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 170.89 E-value: 7.15e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 163 IAEQNSRIPLELSLLREQDLSPIERSKLLADEEQMTSYINQQGSMILLAAVDENTWLRVEDNISYQTQLKLTTAIGGFFF 242
Cdd:COG5002 20 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 243 LAISVALVMWIYPLWRDLKRLVKTANEFGQGVLSRRATTSRLSVVSQLSHSFNNMANNIEKLIASQRTLTNAVAHDLRTP 322
Cdd:COG5002 100 ALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRREFVANVSHELRTP 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 323 LYRLRFAFEMLEDEDIALS-QKEKYRQVIHSSIEDLDHLINQTLVLSRYNRITDIRHFSYCHFADnLVAEA-EHFQLENP 400
Cdd:COG5002 180 LTSIRGYLELLLDGAADDPeERREYLEIILEEAERLSRLVNDLLDLSRLESGELKLEKEPVDLAE-LLEEVvEELRPLAE 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 401 QLTLRVSVLDSLRQQTIFVDNRALLRAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFT 478
Cdd:COG5002 259 EKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEggTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFY 338
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1841552669 479 QVNNQERNSEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFELQWPK 529
Cdd:COG5002 339 RVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVE---SEPGkGTTFTITLPL 387
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
302-529 |
2.20e-47 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 165.08 E-value: 2.20e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 302 EKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLED-EDIALSQKEKYRQVIHSSIEDLDHLINQTLVLSRYNRITDIRHFS 380
Cdd:COG2205 10 EELERLKSEFLANVSHELRTPLTSILGAAELLLDeEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGKLSLELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 381 YCHFADnLVAEA-EHFQLENPQLTLRVSVLDSLRQQTIFVDNRALLRAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLV 457
Cdd:COG2205 90 PVDLAE-LLEEAvEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPggTITISARREGDGVRIS 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1841552669 458 VEDDGPGIAPDDIERIFEPFTQVNNqeRNSEKGHGLGLAIVKQITRWHQGKVRVKVNGSalGGACFELQWPK 529
Cdd:COG2205 169 VSDNGPGIPEEELERIFERFYRGDN--SRGEGGTGLGLAIVKRIVEAHGGTIWVESEPG--GGTTFTVTLPL 236
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
216-534 |
3.61e-38 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 145.44 E-value: 3.61e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 216 NTWLRV------EDNISYQTqlKLTTAIGgffflAISVALVMW-IYPLWRDLKRLVKTANEFGQGV----LSRRATTSRL 284
Cdd:PRK09467 137 NIWVRVplteihQGDFSPLF--RYTLAIG-----LLSVAGGWLfIRIQNRPLVALEHAALQVGKGEipppLREYGASEVR 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 285 SVvsqlSHSFNNMANNIeKLIASQRTLTNA-VAHDLRTPLYRLRFAFEMLEDEDIALSQKekyrqvIHSSIEDLDHLINQ 363
Cdd:PRK09467 210 SV----TRAFNQMAAGI-KQLEDDRTLLMAgVSHDLRTPLTRIRLATEMMSEEDGYLAES------INKDIEECNAIIEQ 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 364 TlvlsrynrITDIRH-----FSYCHFADNL--VAEAEHFQLENPQLTLrvsvldSLRQQTIFVDNRALLRAVKNLLSNAA 436
Cdd:PRK09467 279 F--------IDYLRTgqempMEMADLNALLgeVIAAESGYEREIETAL------QPGPIEVPMNPIAIKRALANLVVNAA 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 437 RFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQvNNQERNSEkGHGLGLAIVKQITRWHQGKvrVKVNGS 516
Cdd:PRK09467 345 RYGNGWIKVSSGTEGKRAWFQVEDDGPGIPPEQLKHLFQPFTR-GDSARGSS-GTGLGLAIVKRIVDQHNGK--VELGNS 420
|
330
....*....|....*...
gi 1841552669 517 ALGGACFelqwpkQISLP 534
Cdd:PRK09467 421 EEGGLSA------RAWLP 432
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
144-511 |
4.12e-34 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 134.44 E-value: 4.12e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 144 LYLAVENLRSQPRTQWQTSIAEQNSRIPLELSLLREQDLSPIERSKLLADEEQMTSYINQQGSMILLAAVDENTWLRVED 223
Cdd:TIGR01386 81 LALSILNPDGRLLFERAQGAALVPAVAANDALLELDQADAKMTHYRSILRSVAALPGGKGRKPVQITVALDINAHTHLLD 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 224 niSYQTQLKLTTAIGGFfflaISVALVMWIYPL-WRDLKRLVKTANEFGQGVLSRRATTSRLSV-VSQLSHSFNNMANNI 301
Cdd:TIGR01386 161 --ALRKWLILIAVLLVL----LTALLGWWITRLgLEPLRRLSAVAARISPESLDQRLDPSRAPAeLRELAQSFNAMLGRL 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 302 EKLIASQRTLTNAVAHDLRTPLYRLrfafeMLEDEdIALSQK---EKYRQVIHSSIEDLDHL---INQTLVLSRYNRITD 375
Cdd:TIGR01386 235 EDAFQRLSQFSADLAHELRTPLTNL-----LGQTQ-VALSQPrtgEEYREVLESNLEELERLsrmVSDMLFLARADNGQL 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 376 IRHFSYCHFADNLVAEAEHFQL--ENPQLTLRVSVLDSLRqqtifVDNRALLRAVKNLLSNAARFAQQ--EIHLSLNESN 451
Cdd:TIGR01386 309 ALERVRLDLAAELAKVAEYFEPlaEERGVRIRVEGEGLVR-----GDPQMFRRAISNLLSNALRHTPDggTITVRIERRS 383
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 452 GQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQITRWHQGKVRV 511
Cdd:TIGR01386 384 DEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRASA 443
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-528 |
3.80e-32 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 119.07 E-value: 3.80e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQITR 503
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRVAL 80
|
90 100
....*....|....*....|....*
gi 1841552669 504 WHQGkvRVKVNGSALGGACFELQWP 528
Cdd:cd16939 81 WHGG--HVECDDSELGGACFRLTWP 103
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
420-530 |
4.12e-31 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 116.59 E-value: 4.12e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 420 DNRALLRAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEkGHGLGLAI 497
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIKYTPEggRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIG-GTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|...
gi 1841552669 498 VKQITRWHQGkvRVKVNGSALGGACFELQWPKQ 530
Cdd:smart00387 81 VKKLVELHGG--EISVESEPGGGTTFTITLPLE 111
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
245-528 |
5.23e-31 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 125.43 E-value: 5.23e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 245 ISVALVMWI-YPLWRDLKRLVKTANEFGQGVLSRRAT-TSRLSVVSQLSHSFNNMANNIEKLIASQRTLTNAVAHDLRTP 322
Cdd:PRK09470 178 VSTPLLLWLaWSLAKPARKLKNAADEVAQGNLRQHPElETGPQEFRQAGASFNQMVTALERMMTSQQRLLSDISHELRTP 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 323 LYRLRFAFEML-----EDEDIalsqkekyrQVIHSSIEDLDHLINQTLVLSR--YNRITDIRHFSYCHFADNLVAEAEhF 395
Cdd:PRK09470 258 LTRLQLATALLrrrqgESKEL---------ERIETEAQRLDSMINDLLVLSRnqQKNHLERETFKANSLWSEVLEDAK-F 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 396 QLENPQLTLRVSVLdsLRQQTIFVDNRALLRAVKNLLSNAARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFE 475
Cdd:PRK09470 328 EAEQMGKSLTVSAP--PGPWPINGNPNALASALENIVRNALRYSHTKIEVAFSVDKDGLTITVDDDGPGVPEEEREQIFR 405
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1841552669 476 PFTQVNNQERNSEKGHGLGLAIVKQITRWHQGKvrVKVNGSALGGACFELQWP 528
Cdd:PRK09470 406 PFYRVDEARDRESGGTGLGLAIVENAIQQHRGW--VKAEDSPLGGLRLTIWLP 456
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
300-530 |
1.74e-28 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 117.76 E-value: 1.74e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 300 NIEKLIASQRT-----LTNAVAHDLRTPL-------YRLRFAFEMLEDEDIAlsQKEKYRQVIHSSIEDLDHLINQtlvL 367
Cdd:COG5000 188 DITELLRAERLaawgeLARRIAHEIKNPLtpiqlsaERLRRKLADKLEEDRE--DLERALDTIIRQVDRLKRIVDE---F 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 368 SRYNRITDIrHFSYCHFADnLVAEAEHF---QLENPQLTLRVSVLDSLRQqtIFVDNRALLRAVKNLLSNA--ARFAQQE 442
Cdd:COG5000 263 LDFARLPEP-QLEPVDLNE-LLREVLALyepALKEKDIRLELDLDPDLPE--VLADRDQLEQVLINLLKNAieAIEEGGE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 443 IHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPF--TQvnnqernsEKGHGLGLAIVKQITRWHQGKVRVKvngSALG- 519
Cdd:COG5000 339 IEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFftTK--------PKGTGLGLAIVKKIVEEHGGTIELE---SRPGg 407
|
250
....*....|.
gi 1841552669 520 GACFELQWPKQ 530
Cdd:COG5000 408 GTTFTIRLPLA 418
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
50-530 |
2.16e-28 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 118.73 E-value: 2.16e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 50 FTFLSEKLRQAPQAEWTTIIDGYAKHFSYPLRLEALDSYHSSPEVYQALQKGEIIFQDGDPMALLQRVLNSDKVLYFAIN 129
Cdd:COG4251 18 LLLLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 130 EPRELAALNQSRGTLYLAVENLRSQPRTQWQTSIAEQNSRIPLELSLLREQDLSPIERSKLLADEEQMTSYINQQGSMIL 209
Cdd:COG4251 98 LVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 210 LAAVDENTWLRVEDNISYQTQLKLTTAIGGFFFLAISVALVMWIYPLWRDLKRLVKTANE---FGQGVLSRRATTSRLSV 286
Cdd:COG4251 178 LELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLlllLILLLLLLILVLELLEL 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 287 VSQLSHSFNNMANNIEKLIASQRTL---TNAVAHDLRTPLYRLRFAFEML-EDEDIALSQK-EKYRQVIHSSIEDLDHLI 361
Cdd:COG4251 258 RLELEELEEELEERTAELERSNEELeqfAYVASHDLREPLRKISGFSQLLeEDYGDKLDEEgREYLERIRDAAERMQALI 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 362 NQTLVLSRYNRITDirHFSYCHFADnLVAEA-EHFQLENPQLTLRVSVLDSLrqqTIFVDNRALLRAVKNLLSNAARF-- 438
Cdd:COG4251 338 DDLLAYSRVGRQEL--EFEPVDLNE-LLEEVlEDLEPRIEERGAEIEVGPLP---TVRGDPTLLRQVFQNLISNAIKYsr 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 439 --AQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSekGHGLGLAIVKQITRWHQGKVRVKvngS 516
Cdd:COG4251 412 pgEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEYE--GTGIGLAIVKKIVERHGGRIWVE---S 486
|
490
....*....|....*
gi 1841552669 517 ALG-GACFELQWPKQ 530
Cdd:COG4251 487 EPGeGATFYFTLPKA 501
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
424-527 |
1.09e-26 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 103.84 E-value: 1.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQErnSEKGHGLGLAIVKQI 501
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPggTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSR--EGGGTGLGLAIVRRI 78
|
90 100
....*....|....*....|....*.
gi 1841552669 502 TRWHQGkvRVKVNGSALGGACFELQW 527
Cdd:cd00075 79 VEAHGG--RITVESEPGGGTTFTVTL 102
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
420-531 |
1.82e-26 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 103.60 E-value: 1.82e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 420 DNRALLRAVKNLLSNAARFAQQ--EIHLSLnESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVnnqERNSEKGHGLGLAI 497
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHAAKagEITVTL-SEGGELTLTVEDNGIGIPPEDLPRIFEPFSTA---DKRGGGGTGLGLSI 77
|
90 100 110
....*....|....*....|....*....|....
gi 1841552669 498 VKQITRWHQGKVRVKvnGSALGGACFELQWPKQI 531
Cdd:pfam02518 78 VRKLVELLGGTITVE--SEPGGGTTVTLTLPLAQ 109
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
302-528 |
3.89e-23 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 101.03 E-value: 3.89e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 302 EKLIASQR-----TLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDLDH---LINQTLVLSRYNRi 373
Cdd:COG4191 131 EQLVQSEKlaalgELAAGIAHEINNPLAAILGNAELLRRRLEDEPDPEELREALERILEGAERaaeIVRSLRAFSRRDE- 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 374 TDIRHFSYCHFADNLVAEAEHfQLENPQLTLRVSVLDSLRQqtIFVDNRALLRAVKNLLSNAA----RFAQQEIHLSLNE 449
Cdd:COG4191 210 EEREPVDLNELIDEALELLRP-RLKARGIEVELDLPPDLPP--VLGDPGQLEQVLLNLLINAIdameEGEGGRITISTRR 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 450 SNGQLFLVVEDDGPGIAPDDIERIFEPF--TqvnnqeRNSEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFELQ 526
Cdd:COG4191 287 EGDYVVISVRDNGPGIPPEVLERIFEPFftT------KPVGKGTGLGLSISYGIVEKHGGRIEVE---SEPGgGTTFTIT 357
|
..
gi 1841552669 527 WP 528
Cdd:COG4191 358 LP 359
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-529 |
5.77e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 93.54 E-value: 5.77e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVnNQERNSEK-GHGLGLAIVKQIT 502
Cdd:cd16949 1 LARALENVLRNALRYSPSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRV-DSARDRESgGTGLGLAIAERAI 79
|
90 100
....*....|....*....|....*..
gi 1841552669 503 RWHQGKVRVKvNGSaLGGACFELQWPK 529
Cdd:cd16949 80 EQHGGKIKAS-NRK-PGGLRVRIWLPA 104
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
243-529 |
2.27e-22 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 100.30 E-value: 2.27e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 243 LAISVALVMWIYplwRDLKRLVKTANEFGQGvlsRRATTSRLSV--VSQLSHSFNNM------ANNIEKLIasqRTLTna 314
Cdd:PRK11100 196 LLIGAGVVWWLN---RSIRRLTRYADAVTEG---KPVPLPKLGSseLRELAQALESMrvklegKAYVEQYV---QTLT-- 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 315 vaHDLRTPLYRLRFAFEMLEDEdiaLSQKEkyRQVIHSSIED----LDHLINQTLVLSRYNRITDIRHFSYCHFADNL-- 388
Cdd:PRK11100 265 --HELKSPLAAIRGAAELLQED---PPPED--RARFTGNILTqsarLQQLIDRLLELARLEQRQELEVLEPVALAALLee 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 389 VAEAEHFQLENPQLTLRVSVlDSLRQQTifvdNRALLR-AVKNLLSNAARFAQQ--EIHLSLNESNGQLFLVVEDDGPGI 465
Cdd:PRK11100 338 LVEAREAQAAAKGITLRLRP-DDARVLG----DPFLLRqALGNLLDNAIDFSPEggTITLSAEVDGEQVALSVEDQGPGI 412
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841552669 466 aPD-DIERIFEPF--TQVNNQERnseKGHGLGLAIVKQITRWHQGKVRVKvNGsALGGACFELQWPK 529
Cdd:PRK11100 413 -PDyALPRIFERFysLPRPANGR---KSTGLGLAFVREVARLHGGEVTLR-NR-PEGGVLATLTLPR 473
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
224-534 |
3.01e-22 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 99.71 E-value: 3.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 224 NISYQTQLKLTTaiggFFFLAISV---ALVMWiyPLWRDL----KRLVKTANEFGQGVLSRRATTSRLSVVSQLSHSFNN 296
Cdd:PRK10549 155 DINFDKQQRRTS----WLIVALSTllaALATF--LLARGLlapvKRLVEGTHKLAAGDFTTRVTPTSRDELGRLAQDFNQ 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 297 MANNIEKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLED-------EDIALSQKEkyrqvihssIEDLDHLINQTLVLSr 369
Cdd:PRK10549 229 LASTLEKNEQMRRDFMADISHELRTPLAVLRGELEAIQDgvrkftpESVASLQAE---------VGTLTKLVDDLHQLS- 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 370 ynrITDIRHFSYCHFADNLV------AEAEHFQLENPQLTLRVSVLDslrQQTIFVDNRALLRAVKNLLSNAARF--AQQ 441
Cdd:PRK10549 299 ---LSDEGALAYRKTPVDLVpllevaGGAFRERFASRGLTLQLSLPD---SATVFGDPDRLMQLFNNLLENSLRYtdSGG 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 442 EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQITRWHQGKVRVKvnGSALGGA 521
Cdd:PRK10549 373 SLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAA--HSPFGGV 450
|
330
....*....|...
gi 1841552669 522 CFELQWPKQISLP 534
Cdd:PRK10549 451 SITVELPLERDLQ 463
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
415-524 |
3.15e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 92.31 E-value: 3.15e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 415 QTIFVDNRALLRAVKNLLSNAARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQernsEKGHGLG 494
Cdd:cd16954 29 LRFPGERNDLMELLGNLLDNACKWCLEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQ----RPGQGLG 104
|
90 100 110
....*....|....*....|....*....|
gi 1841552669 495 LAIVKQITRWHQGKvrVKVNGSALGGACFE 524
Cdd:cd16954 105 LAIAKEIVEQYGGE--LSLSDSPLGGARFE 132
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
244-527 |
1.21e-21 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 97.80 E-value: 1.21e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 244 AISVALVMWIYPLWRDLKRLVKTANEfgqgvLSRRA--------TTSRLSVVSQLSHSFNNMANNIEKLIASQRTLTNAV 315
Cdd:PRK10337 170 ALPIMLIILMVLLGRELAPLKKLALA-----LRMRDpdsetplnATGVPSEVRPLVEALNQLFARTHAMMVRERRFTSDA 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 316 AHDLRTPLYRLRFAFEM--LEDEDIALsqKEKYRQVIHSSIEDLDHLINQTLVLSRYNRITDIRHFSYCHFADNL---VA 390
Cdd:PRK10337 245 AHELRSPLAALKVQTEVaqLSDDDPQA--RKKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLqsaVM 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 391 EAEHF-QLENPQLTLRVSVLDSLRQqtifvdNRALLRA--VKNLLSNAARFAQQ--EIHLSLNESNgqlfLVVEDDGPGI 465
Cdd:PRK10337 323 DIYHTaQQAGIDVRLTLNAHPVIRT------GQPLLLSllVRNLLDNAIRYSPQgsVVDVTLNARN----FTVRDNGPGV 392
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1841552669 466 APDDIERIFEPFTQVNNQErnsEKGHGLGLAIVKQITRWHQgkVRVKVNGSALGGACFELQW 527
Cdd:PRK10337 393 TPEALARIGERFYRPPGQE---ATGSGLGLSIVRRIAKLHG--MNVSFGNAPEGGFEAKVSW 449
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
241-528 |
9.28e-21 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 96.63 E-value: 9.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 241 FFLAISVALVMWIY---PLWRdlkrLVKTANEFGQGVLSRRATTSRLSVVSQLSHSFNNMAN-------NIEKLIAsQRT 310
Cdd:PRK15347 307 VLLTSVLFLLLRRYlakPLWR----FVDIINKTGPAALEPRLPENRLDELGSIAKAYNQLLDtlneqydTLENKVA-ERT 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 311 LT-------------------NAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEkYRQVIHSSIEDLDHLINQTLVLSRYN 371
Cdd:PRK15347 382 QAlaeakqraeqankrksehlTTISHEIRTPLNGVLGALELLQNTPLTAEQMD-LADTARQCTLSLLAIINNLLDFSRIE 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 372 RITDIRHFSYCH---FADNLVAEAeHFQLENPQLTLRVSV---------LDSLRQQTIFVdnrallravkNLLSNAARFA 439
Cdd:PRK15347 461 SGQMTLSLEETAllpLLDQAMLTI-QGPAQSKSLTLRTFVgahvplylhLDSLRLRQILV----------NLLGNAVKFT 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 440 QQ-EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQernsEKGHGLGLAIVKQITRWHQGKVRVKvngSAL 518
Cdd:PRK15347 530 ETgGIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADTH----SQGTGLGLTIASSLAKMMGGELTLF---STP 602
|
330
....*....|.
gi 1841552669 519 G-GACFELQWP 528
Cdd:PRK15347 603 GvGSCFSLVLP 613
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
430-525 |
9.60e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 87.55 E-value: 9.60e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 430 NLLSNAARFAQQ-EIHLSLN-----ESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQITR 503
Cdd:cd16922 7 NLLGNAIKFTEEgEVTLRVSleeeeEDGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAISKKLVE 86
|
90 100
....*....|....*....|...
gi 1841552669 504 WHQGKVRVKvngSALG-GACFEL 525
Cdd:cd16922 87 LMGGDISVE---SEPGqGSTFTF 106
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
289-511 |
2.54e-20 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 94.07 E-value: 2.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 289 QLSHSFNNMANNIEKLIASQRTLTNAVAHDLRTPLYRLrfafemLEDEDIALSQ---KEKYRQVIHSSIEDLDHL---IN 362
Cdd:PRK09835 243 QLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNL------ITQTEIALSQsrsQKELEDVLYSNLEELTRMakmVS 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 363 QTLVLSRYNRITDIRHFSYCHFADNLVAEAEHFQL--ENPQLTLRVSVldslRQQTIFVDNRALLRAVKNLLSNAARF-- 438
Cdd:PRK09835 317 DMLFLAQADNNQLIPEKKMLDLADEVGKVFDFFEAwaEERGVELRFVG----DPCQVAGDPLMLRRAISNLLSNALRYtp 392
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1841552669 439 AQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVN-NQERNSEkGHGLGLAIVKQITRWHQGKVRV 511
Cdd:PRK09835 393 AGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDpSRQRKGE-GSGIGLAIVKSIVVAHKGTVAV 465
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-528 |
1.66e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 83.65 E-value: 1.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQeRNSeKGHGLGLAIVKQITR 503
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNA-RGT-SGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|....*
gi 1841552669 504 WHQGKVRVKvnGSALGGACFELQWP 528
Cdd:cd16950 79 AHGGSLTLA--NRAGGGLCARIELP 101
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
302-528 |
6.20e-19 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 88.36 E-value: 6.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 302 EKLiASQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEkYRQVIHSSIEDLDHLINQTLVLSRyNRITDIRHFSY 381
Cdd:COG3852 130 EKL-AAVGELAAGLAHEIRNPLTGIRGAAQLLERELPDDELRE-YTQLIIEEADRLNNLVDRLLSFSR-PRPPEREPVNL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 382 CHFADNLV--AEAEHfqleNPQLTLRVSVLDSLRqqTIFVDNRALLRAVKNLLSNAA-------------RFAQQeIHLS 446
Cdd:COG3852 207 HEVLERVLelLRAEA----PKNIRIVRDYDPSLP--EVLGDPDQLIQVLLNLVRNAAeampeggtitirtRVERQ-VTLG 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 447 LNESNGQLFLVVEDDGPGIAPDDIERIFEPF-TqvnnqerNSEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFE 524
Cdd:COG3852 280 GLRPRLYVRIEVIDNGPGIPEEILDRIFEPFfT-------TKEKGTGLGLAIVQKIVEQHGGTIEVE---SEPGkGTTFR 349
|
....
gi 1841552669 525 LQWP 528
Cdd:COG3852 350 IYLP 353
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
315-535 |
7.40e-19 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 88.91 E-value: 7.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 315 VAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDLDHLINQTLVLSR--------YNRITDIRhfsychfAD 386
Cdd:PRK11006 211 VSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKieaaptidLNEKVDVP-------MM 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 387 NLVAEAEHFQLENPQLTLRVSVLDSLRqqtIFVDNRALLRAVKNLLSNAARFAQQEIHLS---LNESNGQLFlVVEDDGP 463
Cdd:PRK11006 284 LRVLEREAQTLSQGKHTITFEVDNSLK---VFGNEDQLRSAISNLVYNAVNHTPEGTHITvrwQRVPQGAEF-SVEDNGP 359
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1841552669 464 GIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFELQWPKQISLPN 535
Cdd:PRK11006 360 GIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIE---SEVGkGTRFSFVLPERLIAKN 429
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
311-528 |
2.43e-18 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 88.49 E-value: 2.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 311 LTNAVAHDLRTPLYRLRFAFEMLEDEDiALSQKEKYRQVIHSSIEDLDHLINQTLVLSRYNRITdIRHFSYCHFADN--- 387
Cdd:PRK11360 393 LVAGVAHEIRNPLTAIRGYVQIWRQQT-SDPPSQEYLSVVLREVDRLNKVIDQLLEFSRPRESQ-WQPVSLNALVEEvlq 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 388 LVAEAEHFQlenpqltlRVSVLDSLRQQ--TIFVDNRALLRAVKNLLSNAARFAQQEIHLSL---NESNGQLFLVVEDDG 462
Cdd:PRK11360 471 LFQTAGVQA--------RVDFETELDNElpPIWADPELLKQVLLNILINAVQAISARGKIRIrtwQYSDGQVAVSIEDNG 542
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1841552669 463 PGIAPDDIERIFEPF--TQvnnqernsEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFELQWP 528
Cdd:PRK11360 543 CGIDPELLKKIFDPFftTK--------AKGTGLGLALSQRIINAHGGDIEVE---SEPGvGTTFTLYLP 600
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
283-529 |
2.54e-17 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 84.64 E-value: 2.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 283 RLSVVSQLShsfnnmanniekliASqrtltnaVAHDLRTPLYRLRFAFEMLEDEDiaLSQKEKYRQVIHSSIEDLDHLIN 362
Cdd:COG5809 266 KLSVVGELA--------------AG-------IAHEIRNPLTSLKGFIQLLKDTI--DEEQKTYLDIMLSELDRIESIIS 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 363 QTLVLSRyNRITDIRHFSYCHFADNLVaeaehfQLENPQltlrvSVLDSLRQQTIFVDNRALLRAVK--------NLLSN 434
Cdd:COG5809 323 EFLVLAK-PQAIKYEPKDLNTLIEEVI------PLLQPQ-----ALLKNVQIELELEDDIPDILGDEnqlkqvfiNLLKN 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 435 AARF--AQQEIHLSLN-ESNGQLFLVVEDDGPGIAPDDIERIFEPF-TqvnnqerNSEKGHGLGLAIVKQITRWHQGKVR 510
Cdd:COG5809 391 AIEAmpEGGNITIETKaEDDDKVVISVTDEGCGIPEERLKKLGEPFyT-------TKEKGTGLGLMVSYKIIEEHGGKIT 463
|
250 260
....*....|....*....|
gi 1841552669 511 VKvngSALG-GACFELQWPK 529
Cdd:COG5809 464 VE---SEVGkGTTFSITLPI 480
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
403-530 |
2.96e-17 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 83.74 E-value: 2.96e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 403 TLRVSVLDSLRQQTIfvDNRALLRAVKNLLSNA------ARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEP 476
Cdd:COG3290 263 DLTIDIDSDLPDLPL--SDTDLVTILGNLLDNAieavekLPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFER 340
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1841552669 477 --FTQvnnqernSEKGHGLGLAIVKQITRWHQGKVRVKVNGsaLGGACFELQWPKQ 530
Cdd:COG3290 341 gfSTK-------LGEGRGLGLALVKQIVEKYGGTIEVESEE--GEGTVFTVRLPKE 387
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
426-528 |
3.53e-16 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 74.45 E-value: 3.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 426 RAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLV-VEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQIT 502
Cdd:cd16925 7 RVVLNLLSNAFKFTPDggRIRCILEKFRLNRFLLtVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLSIVKEFV 86
|
90 100
....*....|....*....|....*.
gi 1841552669 503 RWHQGKvrVKVNGSALGGACFELQWP 528
Cdd:cd16925 87 ELHGGT--VTVSDAPGGGALFQVELP 110
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-520 |
3.55e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 74.36 E-value: 3.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 422 RALLR-AVKNLLSNAARFAQQ--EIHLSLNESNGQLFlVVEDDGPGIAPDDIERIFEPFTQVNNQernSEKGHGLGLAIV 498
Cdd:cd16940 11 ALLLFlLLRNLVDNAVRYSPQgsRVEIKLSADDGAVI-RVEDNGPGIDEEELEALFERFYRSDGQ---NYGGSGLGLSIV 86
|
90 100
....*....|....*....|..
gi 1841552669 499 KQITRWHQGKVRVkvnGSALGG 520
Cdd:cd16940 87 KRIVELHGGQIFL---GNAQGG 105
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
261-528 |
3.07e-15 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 78.92 E-value: 3.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 261 KRLVKT-----ANEFGQGVLSRRATTSRL-SVVSQLSHSfnnmanniekliasqrtLTNAVAHDLRTPLYRLRFAFEMLE 334
Cdd:PRK10490 628 QRLLETftlliANALERLTLTASEEQARLaSEREQLRNA-----------------LLAALSHDLRTPLTVLFGQAEILT 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 335 dEDIALSQKEKYRQV--IHSSIEDLDHLINQTLVLSRYnritdirhfsychfadnlvaEAEHFQLENPQLTLRVSVLDSL 412
Cdd:PRK10490 691 -LDLASEGSPHARQAseIRQQVLNTTRLVNNLLDMARI--------------------QSGGFNLRKEWLTLEEVVGSAL 749
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 413 RQ------------------QTIFVDNRALLRAVKNLLSNAARFA--QQEIHLSLNESNGQLFLVVEDDGPGIAPDDIER 472
Cdd:PRK10490 750 QMlepglsghpinlslpeplTLIHVDGPLFERVLINLLENAVKYAgaQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQL 829
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1841552669 473 IFEPFTQVNNQerNSEKGHGLGLAIVKQITRWHQGKVRvkVNGSALGGACFELQWP 528
Cdd:PRK10490 830 IFDKFARGNKE--SAIPGVGLGLAICRAIVEVHGGTIW--AENRPEGGACFRVTLP 881
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
428-528 |
4.14e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 71.16 E-value: 4.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 428 VKNLLSNA--ARFAQQ----EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEP-FTQvnnqerNSEKGHGLGLAIVKQ 500
Cdd:cd16915 5 VGNLIDNAldALAATGapnkQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERgVST------KGQGERGIGLALVRQ 78
|
90 100
....*....|....*....|....*...
gi 1841552669 501 ITRWHQGKVRVKVNgsALGGACFELQWP 528
Cdd:cd16915 79 SVERLGGSITVESE--PGGGTTFSIRIP 104
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
280-535 |
6.83e-15 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 76.16 E-value: 6.83e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 280 TTSRLSVVSQLSHSFNNmanniekliasQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRqvihssIEDLDH 359
Cdd:PRK10755 120 TSALNQLVSRLTSTLDQ-----------ERLFTADVAHELRTPLAGIRLHLELLEKQHHIDVAPLIAR------LDQMMH 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 360 LINQTLVLSR---------YNR---ITDIRHFSYCHFADNLVAEAEHFQLENPQLTLRVsvldslrqqtifVDNRALLR- 426
Cdd:PRK10755 183 TVEQLLQLARagqsfssghYQTvklLEDVILPSQDELSEMLEQRQQTLLLPESAADITV------------QGDATLLRl 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 427 AVKNLLSNAARFAQQE--IHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFtqVNNQERNSekGHGLGLAIVKQITRW 504
Cdd:PRK10755 251 LLRNLVENAHRYSPEGstITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAF--VRMDSRYG--GIGLGLSIVSRITQL 326
|
250 260 270
....*....|....*....|....*....|.
gi 1841552669 505 HQGKVRVKvNGSALGGACFELQWPKQISLPN 535
Cdd:PRK10755 327 HHGQFFLQ-NRQERSGTRAWVWLPKAQNVAN 356
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
428-525 |
8.37e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 70.18 E-value: 8.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 428 VKNLLSNA----ARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVnnqeRNSEKGHGLGLAIVKQITR 503
Cdd:cd16976 5 LMNLLQNAldamGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTT----KPVGKGTGLGLSISYGIVE 80
|
90 100
....*....|....*....|..
gi 1841552669 504 WHQGKVRVKVNGSalGGACFEL 525
Cdd:cd16976 81 EHGGRLSVANEEG--AGARFTF 100
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
298-525 |
2.59e-14 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 76.13 E-value: 2.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 298 ANNIEKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIAlSQKEKYRQVIHSS----------IEDLD-------HL 360
Cdd:PRK11091 273 QDALEKASRDKTTFISTISHELRTPLNGIVGLSRILLDTELT-AEQRKYLKTIHVSaitlgnifndIIDMDkmerrklQL 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 361 INQTLVLSRYnrITDIRHFSychfadNLVAEAE--HFQLEnPQLTLrvsvldslrQQTIFVDNRALLRAVKNLLSNAARF 438
Cdd:PRK11091 352 DNQPIDFTDF--LADLENLS------GLQAEQKglRFDLE-PLLPL---------PHKVITDGTRLRQILWNLISNAVKF 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 439 AQQ-EIHLSLN-ESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERN-SEKGHGLGLAIVKQITRWHQGKVRVKvng 515
Cdd:PRK11091 414 TQQgGVTVRVRyEEGDMLTFEVEDSGIGIPEDELDKIFAMYYQVKDSHGGkPATGTGIGLAVSKRLAQAMGGDITVT--- 490
|
250
....*....|.
gi 1841552669 516 SALG-GACFEL 525
Cdd:PRK11091 491 SEEGkGSCFTL 501
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
228-512 |
1.13e-13 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 73.28 E-value: 1.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 228 QTQLKLTTAIGGFFFLAISVALVMWIYplWRdlkrlvktanefgqgvlsRRATTSRLSVVSQLSHSfnnmanniEKLIAS 307
Cdd:PRK10364 186 QAREQRNTLIILFALATVLLASLLAFF--WY------------------RRYLRSRQLLQDEMKRK--------EKLVAL 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 308 QrTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDLDHLINQTLVLSRYNRItdirhfsyCHFADN 387
Cdd:PRK10364 238 G-HLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHL--------ALQAVD 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 388 LVAEAEH-FQL-----ENPQLTLRVSVLDSLrqQTIFVDNRALLRAVKNLLSNA--ARFAQQEIHLSLNESNGQLFLVVE 459
Cdd:PRK10364 309 LNDLINHsLQLvsqdaNSREIQLRFTANDTL--PEIQADPDRLTQVLLNLYLNAiqAIGQHGVISVTASESGAGVKISVT 386
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1841552669 460 DDGPGIAPDDIERIFEPFTQVNNQernsekGHGLGLAIVKQITRWHQGKVRVK 512
Cdd:PRK10364 387 DSGKGIAADQLEAIFTPYFTTKAE------GTGLGLAVVHNIVEQHGGTIQVA 433
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-534 |
1.43e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 66.68 E-value: 1.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARF--AQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVnnqeRNSEKGHGLGLAIVKQI 501
Cdd:cd16943 4 LNQVLLNLLVNAAQAmeGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTT----KPVGEGTGLGLSLSYRI 79
|
90 100 110
....*....|....*....|....*....|....
gi 1841552669 502 TRWHQGKVRVKvngSALG-GACFelqwpkQISLP 534
Cdd:cd16943 80 IQKHGGTIRVA---SVPGgGTRF------TIILP 104
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-512 |
1.95e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 66.33 E-value: 1.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQV---NNQERNSekghGLGLAIV 498
Cdd:cd16945 5 LRQAINNLLDNAIDFSPEggLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLprpHSGQKST----GLGLAFV 80
|
90
....*....|....
gi 1841552669 499 KQITRWHQGKVRVK 512
Cdd:cd16945 81 QEVAQLHGGRITLR 94
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
302-538 |
4.35e-13 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 72.25 E-value: 4.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 302 EKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEkYRQVIHSSIEDLDHLINQTLVLSR-----YNRITDI 376
Cdd:PRK11466 438 EKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRD-DLRAITDSGESLLTILNDILDYSAieaggKNVSVSD 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 377 RHFSYCHFADNLVAEAeHFQLENPQLTLRVSVLDSLrQQTIFVDNRALLRAVKNLLSNAARFAQQ-EIHLSLNESNGQLF 455
Cdd:PRK11466 517 EPFEPRPLLESTLQLM-SGRVKGRPIRLATDIADDL-PTALMGDPRRIRQVITNLLSNALRFTDEgSIVLRSRTDGEQWL 594
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 456 LVVEDDGPGIAPDDIERIFEPFTQVNNQernsEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFELQWPKQISLP 534
Cdd:PRK11466 595 VEVEDSGCGIDPAKLAEIFQPFVQVSGK----RGGTGLGLTISSRLAQAMGGELSAT---STPEvGSCFCLRLPLRVATA 667
|
....
gi 1841552669 535 NVTK 538
Cdd:PRK11466 668 PVPK 671
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
420-528 |
1.30e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 64.10 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 420 DNRALLRAVKNLLSNAARFAQQ----EIHLSLNESNGQ---LFLVVEDDGPGIAPDDIERIFEPFTQvnnqerNSEKGHG 492
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGrpsdVGEVRIRVEADQdgrIVLIVCDNGKGFPREMRHRATEPYVT------TRPKGTG 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 1841552669 493 LGLAIVKQITRWHQGkvRVKVNGSALGGACFELQWP 528
Cdd:cd16944 75 LGLAIVKKIMEEHGG--RISLSNREAGGACIRIILP 108
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
420-528 |
2.77e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 63.25 E-value: 2.77e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 420 DNRALLRAVKNLLSNAARFAQQ--EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAI 497
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTggKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAI 80
|
90 100 110
....*....|....*....|....*....|.
gi 1841552669 498 VKQITRWHQGkvRVKVNGSALGGACFELQWP 528
Cdd:cd16946 81 CHNIALAHGG--TISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-528 |
4.28e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 62.98 E-value: 4.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQE---IHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQ 500
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDtgrITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSGLGLSISRQ 80
|
90 100 110
....*....|....*....|....*....|.
gi 1841552669 501 ITRWHQGKVRVKV---NGSALgGACFELQWP 528
Cdd:cd16953 81 IIEAHGGISVAENhnqPGQVI-GARFTVQLP 110
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
420-522 |
4.41e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 62.86 E-value: 4.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 420 DNRALLRAVKNLLSNAARFAQQEIHLSLNESNGQ--LFLVVEDDGPGIAPDDIERIFEPFTQvNNQERNSEKGHGLGLAI 497
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEeyLYFEIWDNGHGFSEQDLKKALELFYR-DDTSRRSGGHYGMGLYI 79
|
90 100
....*....|....*....|....*
gi 1841552669 498 VKQITRWHQGKvrVKVNGSALGGAC 522
Cdd:cd16975 80 AKNLVEKHGGS--LIIENSQKGGAE 102
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
255-523 |
5.15e-12 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 67.67 E-value: 5.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 255 PLWrdlKRLVKTANEFGQGVLSRRATTSRLSV-VSQLSHSFNNMANNIEKLIA---SQRTLTNAVAHDLRTPLYRLRFAF 330
Cdd:PRK09303 97 PRW---QQEGATYSGLGENLQPSEIDSGRYSQeLLQLSDELFVLRQENETLLEqlkFKDRVLAMLAHDLRTPLTAASLAL 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 331 EMLE----DEDIALSQK--EKYRQVIHSSIEDLDHLINQTLVLSRynritdirhfsycHFADNLVAEAEHFQLEN--PQL 402
Cdd:PRK09303 174 ETLElgqiDEDTELKPAliEQLQDQARRQLEEIERLITDLLEVGR-------------TRWEALRFNPQKLDLGSlcQEV 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 403 TLRVSVLDSLRQQTI-----------FVDNRALLRAVKNLLSNAARF--AQQEIHLS-LNESNGQLFLVVEDDGPGIAPD 468
Cdd:PRK09303 241 ILELEKRWLAKSLEIqtdipsdlpsvYADQERIRQVLLNLLDNAIKYtpEGGTITLSmLHRTTQKVQVSICDTGPGIPEE 320
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1841552669 469 DIERIFEpfTQVNNQERNSEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACF 523
Cdd:PRK09303 321 EQERIFE--DRVRLPRDEGTEGYGIGLSVCRRIVRVHYGQIWVD---SEPGqGSCF 371
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
297-530 |
7.49e-12 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 67.45 E-value: 7.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 297 MANNIEKL-IASQrtLTNAVAHDLRTPLYRLRFAFEMLEDEdiaLSQKEKYRQVIHSSIEDLDHLINQTLVLSRynriTD 375
Cdd:COG5805 277 LMARSEKLsIAGQ--LAAGIAHEIRNPLTSIKGFLQLLQPG---IEDKEEYFDIMLSELDRIESIISEFLALAK----PQ 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 376 IRHFSYCHFaDNLVAEAehFQLENPQLTLR-VSV-LDSLRQ-QTIFVDNRALLRAVKNLLSNA--ARFAQQEIHLSLNES 450
Cdd:COG5805 348 AVNKEKENI-NELIQDV--VTLLETEAILHnIQIrLELLDEdPFIYCDENQIKQVFINLIKNAieAMPNGGTITIHTEEE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 451 NGQLFLVVEDDGPGIAPDDIERIFEPF-TqvnnqerNSEKGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACFELQWP 528
Cdd:COG5805 425 DNSVIIRVIDEGIGIPEERLKKLGEPFfT-------TKEKGTGLGLMVSYKIIENHNGTIDID---SKVGkGTTFTITLP 494
|
..
gi 1841552669 529 KQ 530
Cdd:COG5805 495 LS 496
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-528 |
2.34e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 60.68 E-value: 2.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQEIHLSL----NESNGQLflVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVK 499
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVrwsqEESGARL--SVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVK 78
|
90 100 110
....*....|....*....|....*....|
gi 1841552669 500 QITRWHQGKVRVKvngSALG-GACFELQWP 528
Cdd:cd16952 79 HVMSRHDARLLIA---SELGkGSRFTCLFP 105
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
420-502 |
4.04e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 59.99 E-value: 4.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 420 DNRALLRAVKNLLSNAARFAQQEIHLSLN--ESNGQLFLVVEDDGPGIAPDDIERIFEP-FTQVNNqeRNSEKGHGLGLA 496
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSKQGGKIEIYseTNEQGVVLSIKDFGIGIPEEDLPRVFDKgFTGENG--RNFQESTGMGLY 79
|
....*.
gi 1841552669 497 IVKQIT 502
Cdd:cd16948 80 LVKKLC 85
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
307-369 |
4.26e-11 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 58.38 E-value: 4.26e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1841552669 307 SQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEkYRQVIHSSIEDLDHLINQTLVLSR 369
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQRE-YLETILRSAERLLRLINDLLDLSR 62
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
452-534 |
7.84e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 58.95 E-value: 7.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 452 GQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQernsekGHGLGLAIVKQITRWHQGKVRVKVNGSalGGACFelqwpkQI 531
Cdd:cd16920 36 RAVTISVKDTGPGIAEEVAGQLFDPFYTTKSE------GLGMGLSICRSIIEAHGGRLSVESPAG--GGATF------QF 101
|
...
gi 1841552669 532 SLP 534
Cdd:cd16920 102 TLP 104
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
419-511 |
8.07e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 59.45 E-value: 8.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 419 VDNRALLRAVKNLLSNAARF--AQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLA 496
Cdd:cd16947 16 ANTEALQRILKNLISNAIKYgsDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSAKQGNGLGLT 95
|
90
....*....|....*
gi 1841552669 497 IVKQITRWHQGKVRV 511
Cdd:cd16947 96 ITKRLAESMGGSIYV 110
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-534 |
8.20e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 58.95 E-value: 8.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAAR-------------FAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQvnnqerNSEKG 490
Cdd:cd16918 1 LIQVFLNLVRNAAQalagsggeiilrtRTQRQVTLGHPRHRLALRVSVIDNGPGIPPDLQDTIFYPMVS------GRENG 74
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1841552669 491 HGLGLAIVKQITRWHQGKVRVKvngSALGGACFelqwpkQISLP 534
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIECD---SQPGHTVF------SVSLP 109
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
307-369 |
8.45e-11 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 57.58 E-value: 8.45e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1841552669 307 SQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEkYRQVIHSSIEDLDHLINQTLVLSR 369
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE-YLETILREAERLLRLINDLLDLSR 62
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
305-369 |
9.60e-11 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 57.61 E-value: 9.60e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1841552669 305 IASQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDLDHLINQTLVLSR 369
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-517 |
3.49e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 57.01 E-value: 3.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 424 LLRAVKNLLSNAARFAQQE--IHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQeRNSEkGHGLGLAIVKQI 501
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENtrIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNS-RNTE-GAGLGLSIAKAI 78
|
90
....*....|....*.
gi 1841552669 502 TRWHQGKVRVKVNGSA 517
Cdd:cd16923 79 IELHGGSASAEYDDNH 94
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-523 |
3.67e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 56.95 E-value: 3.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 430 NLLSNAARF------AQQEIHLSLNEsNGQLFlVVEDDGPGIAPDDIERIFEPFTQVNNQErnSEKGHGLGLAIVKQITR 503
Cdd:cd16921 7 NLLGNAIKFrrprrpPRIEVGAEDVG-EEWTF-YVRDNGIGIDPEYAEKVFGIFQRLHSRE--EYEGTGVGLAIVRKIIE 82
|
90 100
....*....|....*....|.
gi 1841552669 504 WHQGKVRVKvngSALG-GACF 523
Cdd:cd16921 83 RHGGRIWLE---SEPGeGTTF 100
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
84-530 |
6.94e-10 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 61.19 E-value: 6.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 84 ALDSYHSSPEVYQALQKGEIIFQDGDPMALLQRVLNSDKVLYFAINEPRELAALNQSRGTLYLaVENLRSQPRTQWQTSI 163
Cdd:COG2972 4 SLSLLSIVLLLLILLLLVLLILLLSLLLIILLLLLLLILLLLLLILLLLLLLLLLLLLLLLLL-LLLLLLLLLLLALLLI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 164 AEQNSRIPLELSLLREQDLSPIERSKLLADEEQMTSYINQQGSMILLAAVDENTW-----LRVEDNISYQTQLKLTTAIG 238
Cdd:COG2972 83 LLLLLLLLLLLILLLSLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLLGWtlvslIPKSELFRGLFSLRRLILLI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 239 GFFFLAISVALVMWIYP-LWRDLKRLVKTANEFGQGVLSRrATTSRLSVVSQLSHSFNNMANNIEKLIASQRTLTNAVA- 316
Cdd:COG2972 163 ILLLLLLALLLSYLLSRsITRPIKRLKKAMKKVEKGDLVR-LEVSGNDEIGILARSFNEMVERIKELIEEVYELELEKKe 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 317 ------------HDLRTPLYRLRFAFEMLEDEDIalsqkEKYrqvihssIEDLDHLINQTLVLSRyNRIT---DIRHfsy 381
Cdd:COG2972 242 aelkalqaqinpHFLFNTLNSIRWLAELEDPEEA-----EEM-------LEALSKLLRYSLSKGD-ELVTleeELEL--- 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 382 chfADNLVaEAEHFQLENpQLTLRVSVLDSLRQQTI-------FVDNrALLRAVKNLLSNAarfaqqEIHLSLNESNGQL 454
Cdd:COG2972 306 ---IKSYL-EIQKLRFGD-RLEVEIEIDEELLDLLIpklilqpLVEN-AIEHGIEPKEGGG------TIRISIRKEGDRL 373
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841552669 455 FLVVEDDGPGIAPDDIERIFEPFTqvnnqerNSEKGHGLGLAIVKQITRWHQG-KVRVKVNGSALGGACFELQWPKQ 530
Cdd:COG2972 374 VITVEDNGVGMPEEKLEKLLEELS-------SKGEGRGIGLRNVRERLKLYYGeEYGLEIESEPGEGTTVTIRIPLE 443
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
430-530 |
7.42e-10 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 61.19 E-value: 7.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 430 NLLSNAARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQernsEKGHGLGLAIVKQITRWHQGKV 509
Cdd:PRK10815 385 NVLDNACKYCLEFVEISARQTDEHLHIVVEDDGPGIPESKRELIFDRGQRADTL----RPGQGLGLSVAREITEQYEGKI 460
|
90 100
....*....|....*....|.
gi 1841552669 510 RvkVNGSALGGACFELQWPKQ 530
Cdd:PRK10815 461 S--AGDSPLGGARMEVIFGRQ 479
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
310-528 |
1.28e-09 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 60.85 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 310 TLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDLDHLINQTLVLSRYNRITdIRHFSychfADNLV 389
Cdd:PRK13837 452 TLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQILAFGRKGERN-TKPFD----LSELV 526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 390 AEAEhfqlenPQLtlRVSV-------LDSLRQQTIFVDNRALLRAV-KNLLSNAARF----AQQEIHLSLNE-------S 450
Cdd:PRK13837 527 TEIA------PLL--RVSLppgveldFDQDQEPAVVEGNPAELQQVlMNLCSNAAQAmdgaGRVDISLSRAKlrapkvlS 598
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 451 NGQL------FLVVEDDGPGIAPDDIERIFEPFTQVNNQernsekGHGLGLAIVKQITRWHQGKVRVKvngSALG-GACF 523
Cdd:PRK13837 599 HGVLppgryvLLRVSDTGAGIDEAVLPHIFEPFFTTRAG------GTGLGLATVHGIVSAHAGYIDVQ---STVGrGTRF 669
|
....*
gi 1841552669 524 ELQWP 528
Cdd:PRK13837 670 DVYLP 674
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
430-530 |
2.93e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 56.46 E-value: 2.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 430 NLLSNA----ARFAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEpftqvnnqERNSEKG--HGLGLAIVKQITR 503
Cdd:PRK11086 440 NLIENAleavGGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFD--------KGYSTKGsnRGVGLYLVKQSVE 511
|
90 100
....*....|....*....|....*...
gi 1841552669 504 WHQGKVRVKvngSALG-GACFELQWPKQ 530
Cdd:PRK11086 512 NLGGSIAVE---SEPGvGTQFFVQIPWD 536
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
431-502 |
3.25e-07 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 49.14 E-value: 3.25e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1841552669 431 LLSNAARFAQQ-----EIHLSLNESNGQLFLVVEDDGPGIAPDDIErifEPFtqvnnqerNSEKGHGLGLAIVKQIT 502
Cdd:COG2172 42 AVTNAVRHAYGgdpdgPVEVELELDPDGLEIEVRDEGPGFDPEDLP---DPY--------STLAEGGRGLFLIRRLM 107
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
430-497 |
3.33e-07 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 53.44 E-value: 3.33e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1841552669 430 NLLSNAARFAQQE---IHLSLNEsnGQLFLVVEDDGPGIAPDDIERIFEPFTQV-NNQERNSEkGHGLGLAI 497
Cdd:PRK10841 569 NLLSNAIKFTDTGcivLHVRVDG--DYLSFRVRDTGVGIPAKEVVRLFDPFFQVgTGVQRNFQ-GTGLGLAI 637
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
302-528 |
1.42e-06 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 51.23 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 302 EKLIASQRTLTnAVAHDLRTPLYRLRFAFEMLEdediALSQKEKYRQVIHSsIEDLDHLINqtlvlsRYNRI-TDIRHFS 380
Cdd:COG4192 428 AKMAVVGQTMT-SLAHELNQPLNAMSMYLFSAK----KALEQENYAQLPTS-LDKIEGLIE------RMDKIiKSLRQFS 495
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 381 ycHFADNLVAEAEHFQLENPQLTLRVSvlDSLRQQT---------IFVDNRALLRAVKNLLSNA--ARFAQQEIHLSLNE 449
Cdd:COG4192 496 --RKSDTPLQPVDLRQVIEQAWELVES--RAKPQQItlhipddlmVQGDQVLLEQVLVNLLVNAldAVATQPQISVDLLS 571
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 450 SNGQLFLVVEDDGPGIApdDIERIFEPFTQvnnqerNSEKGHGLGLAIVKQITRWHQGKVRVkvnGSAL-GGACFELQWP 528
Cdd:COG4192 572 NAENLRVAISDNGNGWP--LVDKLFTPFTT------TKEVGLGLGLSICRSIMQQFGGDLYL---ASTLeRGAMVILEFN 640
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
422-528 |
1.49e-06 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 49.62 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 422 RALLRAVKNLLSNAARFAQ-QEIHLSLNESNGQLFLVVEDDGPGIAPDDIerifepftqvnnqernseKGHGLGLAIVKQ 500
Cdd:COG4585 161 LALYRIVQEALTNALKHAGaTRVTVTLEVDDGELTLTVRDDGVGFDPEAA------------------PGGGLGLRGMRE 222
|
90 100
....*....|....*....|....*....
gi 1841552669 501 ITRWHQGKVRVkvnGSALG-GACFELQWP 528
Cdd:COG4585 223 RAEALGGTLTI---GSAPGgGTRVRATLP 248
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
302-511 |
3.85e-06 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 49.52 E-value: 3.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 302 EKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLE---DEDIALSQKEKYRQVIHSSIEDLDHLiNQTLVLSRYNRITDIRH 378
Cdd:TIGR02938 270 EERLEAIRETLSAAIHRLQGPMNLISAAISVLQrrgDDAGNPASAAMLQQALSAGREHMEAL-RQVIPQSPQEIVVPVNL 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 379 FSYCHFADNLVAE---AEHFQLE-NPQLTLRVSVLDSLRQQTIF---VDNrallrAVKNLLSNAARfaQQEIHLSLNESN 451
Cdd:TIGR02938 349 NQILRDVITLSTPrllAAGIVVDwQPAATLPAILGRELQLRSLFkalVDN-----AIEAMNIKGWK--RRELSITTALNG 421
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 452 GQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERnseKGHGLGLAIVKQITRWHQGKVRV 511
Cdd:TIGR02938 422 DLIVVSILDSGPGIPQDLRYKVFEPFFTTKGGSR---KHIGMGLSVAQEIVADHGGIIDL 478
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
45-521 |
9.03e-06 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 48.57 E-value: 9.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 45 VYQSNFTFLSEKLRQAPQAEWTTIIDGYAKHFSYPLRLEALDSYHSSPEVYQALQKGEIIFQDGDPMALLQRVLNSDKVL 124
Cdd:COG2770 23 GALLVLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLAL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 125 YFAINEPRELAALNQSRGTLYLAVENLRSQPRTQWQTSIAEQNSRIPLELSLLREQDLSPIERSKLLADEEQMTSYINQQ 204
Cdd:COG2770 103 LLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAA 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 205 GSMILLAAVDENTWLRVEDNISYQTQLKLTTAIGGFFFLAISVALVMWIYPLW--RDLKRLVKTANEFGQGVLSRRATTS 282
Cdd:COG2770 183 IAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRitRPLRRLAEAARRIAAGDLDVRIPVS 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 283 RLSVVSQLSHSFNNMANNIEKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDLDHLIN 362
Cdd:COG2770 263 RKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLL 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 363 QTLVLSRYNRITDIRHFSYCHFADNLVAEAEHFQLENPQLTLRVSVLDSLRQQTIFVDNRALLRAVKNLLSNAARFAQQE 442
Cdd:COG2770 343 LLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALL 422
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1841552669 443 IHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSEKGHGLGLAIVKQITRWHQGKVRVKVNGSALGGA 521
Cdd:COG2770 423 ALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAA 501
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
111-316 |
9.14e-06 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 48.48 E-value: 9.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 111 MALLQRVLNSDKVLYFAINEPRELAALNQSRGTLYLAVENLRSQPRTQWQTSIAEQNSRIPLELSLLREQDLSPIERSKL 190
Cdd:COG0840 64 ALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAAL 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 191 LADEEQMTSYINQQGSMILLAAVDENTWLRVEDNISYQTQLKLTTAIGGFFFLAISVALVMWIyplWRDLKRLVKTANEF 270
Cdd:COG0840 144 ALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSI---TRPLRELLEVLERI 220
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1841552669 271 GQGVLSRRATTSRLSVVSQLSHSFNNMANNIEKLIASQRTLTNAVA 316
Cdd:COG0840 221 AEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVA 266
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
256-306 |
2.87e-05 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 41.46 E-value: 2.87e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1841552669 256 LWRDLKRLVKTANEFGQGVLSRRATTSRLSVVSQLSHSFNNMANNIEKLIA 306
Cdd:smart00304 3 LLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-493 |
2.88e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 42.54 E-value: 2.88e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1841552669 424 LLRAVKNLLSNAARFAQ-QEIHLSLNESNGQLFLVVEDDGPGIAPDDIERifepftqvnnqernsEKGHGL 493
Cdd:cd16917 1 LYRIVQEALTNALKHAGaSRVRVTLSYTADELTLTVVDDGVGFDGPAPPG---------------GGGFGL 56
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
290-531 |
8.04e-05 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 45.50 E-value: 8.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 290 LSHSFNNMANNIEKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDLDHLINQTLVLsr 369
Cdd:PRK09959 694 LIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDV-- 771
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 370 yNRITDIRHFSYCHFAD--NLVAEAEH-FQLENPQLTLRVSVLDSLRQQTIF-VDNRALLRAVKNLLSNAARFAQQ---E 442
Cdd:PRK09959 772 -DKIESGNYQLQPQWVDipTLVQNTCHsFGAIAASKSIALSCSSTFPDHYLVkIDPQAFKQVLSNLLSNALKFTTEgavK 850
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 443 IHLSL---NESNGQLFLVVEDDGPGIAPDDIERIFEPFTQVNNQERNSekGHGLGLAIVKQITRWHQGKVRVKVNGSAlg 519
Cdd:PRK09959 851 ITTSLghiDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQGDLSLESHPGI-- 926
|
250
....*....|..
gi 1841552669 520 GACFELQWPKQI 531
Cdd:PRK09959 927 GTTFTITIPVEI 938
|
|
| HATPase_c_3 |
pfam13589 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ... |
421-509 |
1.36e-04 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain] Cd Length: 135 Bit Score: 41.93 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 421 NRALLRAVKNllSNAARFAQQEIHLSLNESNGQLFlVVEDDGPGIAPDDIERIFEPFTQVNNQERNS----EKGHGLGLA 496
Cdd:pfam13589 2 EGALAELIDN--SIDADATNIKIEVNKNRGGGTEI-VIEDDGHGMSPEELINALRLATSAKEAKRGStdlgRYGIGLKLA 78
|
90
....*....|....*...
gi 1841552669 497 IVKQ-----ITRWHQGKV 509
Cdd:pfam13589 79 SLSLgakltVTSKKEGKS 96
|
|
| HATPase_AgrC-ComD-like |
cd16935 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
415-514 |
1.50e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.
Pssm-ID: 340412 [Multi-domain] Cd Length: 134 Bit Score: 41.79 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 415 QTIFVDNRALLRAVKNLLSNA---ARFAQQE---IHLSLNESNGQLFLVVEDDGPGIAPDDIERIFEpftqvnnqeRNSE 488
Cdd:cd16935 28 ILLPISPLDLCIIFGNLLDNAieaCAKIDKEnrfIHLKIRQKKGFLIISIENSYEGELKKKNGLFLS---------TKKD 98
|
90 100
....*....|....*....|....*.
gi 1841552669 489 KGHGLGLAIVKQITRWHQGKVRVKVN 514
Cdd:cd16935 99 KNHGIGLKSIREIVKKYNGNLSIEYE 124
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
120-473 |
1.57e-04 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 44.49 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 120 SDKVLYFAINEPRELAALNQSRGTLYLAVENLRSQPRTQWQTSIAEQNSRIPLELSLLREQDLSPIERSKLLADEEQMTS 199
Cdd:COG3850 4 LLLLALALLRLLLALLALLLLALLLLSLLALLLLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 200 YINQQGSMILLAAVDENTWLRVEDNISYQTQLKLTTAIGGFFFLAISVALVMWIYPLW--RDLKRLVKTANEFGQGVLSR 277
Cdd:COG3850 84 LLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRivRPLRRLTQAAERIARGDFDA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 278 RATTSRLSVVSQLSHSFNNMANNIEKLIASQRTLTNAVAHDLRTPLYRLRFAFEMLEDEDIALSQKEKYRQVIHSSIEDL 357
Cdd:COG3850 164 RVPVSGRDELGTLARAFNRMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 358 DHLINQTLVLSRYNRITDIRhfsycHFADNLVAEAEHFQLENPQLTLRVSVLDSLRQQTIFVDNRALLRAVKNLLSNAAR 437
Cdd:COG3850 244 LQDALAESELLALNILAGLL-----ELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLL 318
|
330 340 350
....*....|....*....|....*....|....*.
gi 1841552669 438 FAQQEIHLSLNESNGQLFLVVEDDGPGIAPDDIERI 473
Cdd:COG3850 319 LLQAIANASLLLIALASVVAALLELASILALQAALE 354
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
427-505 |
2.09e-04 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 40.33 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 427 AVKNLLSNAARFAQQE-----IHLSLNESNGQLFLVVEDDGPGIAPddiERIFEPftqvnnqeRNSEKGHGLGLAIVKQI 501
Cdd:cd16936 4 AVSEAVTNAVRHAYRHdgpgpVRLELDLDPDRLRVEVTDSGPGFDP---LRPADP--------DAGLREGGRGLALIRAL 72
|
....*
gi 1841552669 502 T-RWH 505
Cdd:cd16936 73 MdEVG 77
|
|
| HAMP |
pfam00672 |
HAMP domain; |
256-303 |
2.56e-04 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 38.76 E-value: 2.56e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1841552669 256 LWRDLKRLVKTANEFGQGVLSRRATTSRLSVVSQLSHSFNNMANNIEK 303
Cdd:pfam00672 6 ILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
258-301 |
4.32e-04 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 38.19 E-value: 4.32e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1841552669 258 RDLKRLVKTANEFGQGVLSRRATTSRLSVVSQLSHSFNNMANNI 301
Cdd:cd06225 2 RPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HATPase_c_2 |
pfam13581 |
Histidine kinase-like ATPase domain; |
403-502 |
7.16e-04 |
|
Histidine kinase-like ATPase domain;
Pssm-ID: 433327 [Multi-domain] Cd Length: 127 Bit Score: 39.58 E-value: 7.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 403 TLRVSVLDSLRQQTIFVDNRALLR-AVKNLLSNAARFAQQE-----IHLSLNESNGQLFLVVEDDGPgiaPDDIERIFEP 476
Cdd:pfam13581 10 AARRVLEAVLRRAGLPEELLDEVElAVGEACTNAVEHAYREgpegpVEVRLTSDGGGLVVTVADSGP---PFDPLTLPPP 86
|
90 100
....*....|....*....|....*.
gi 1841552669 477 ftqVNNQERNSEKGHGLGLAIVKQIT 502
Cdd:pfam13581 87 ---DLEEPDEDRKEGGRGLALIRGLM 109
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
456-511 |
8.28e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 39.29 E-value: 8.28e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1841552669 456 LVVEDDGPGIAPDDIERIFEPFTQVnnqeRNSEKGHGLGLAIVKQITRWHQGKVRV 511
Cdd:cd16919 50 LEVSDTGSGMPAEVLRRAFEPFFTT----KEVGKGTGLGLSMVYGFVKQSGGHLRI 101
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
309-511 |
1.49e-03 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 40.83 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 309 RTLTNAVAHDLRTPLYRLRFAFEMLEDE--DIALSQkekYRQVIhssIEDLDHLINqtLVlsryNRITDIRHFSYcHFAD 386
Cdd:PRK11073 131 RDLVRGLAHEIKNPLGGLRGAAQLLSKAlpDPALTE---YTKVI---IEQADRLRN--LV----DRLLGPQRPGT-HVTE 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 387 NLVAEAEH----FQLENP-QLTLRVSVLDSLRQqtIFVDNRALLRAVKNLLSNAARFAQQE---IHLSLNES-----NGQ 453
Cdd:PRK11073 198 SIHKVAERvvqlVSLELPdNVRLIRDYDPSLPE--LAHDPDQIEQVLLNIVRNALQALGPEggtITLRTRTAfqltlHGE 275
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1841552669 454 LFLV-----VEDDGPGIAPDDIERIFEPFTQvnnqerNSEKGHGLGLAIVKQITRWHQGKVRV 511
Cdd:PRK11073 276 RYRLaaridIEDNGPGIPPHLQDTLFYPMVS------GREGGTGLGLSIARNLIDQHSGKIEF 332
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
431-530 |
4.21e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 39.89 E-value: 4.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1841552669 431 LLSNAARFAQQ-----EIHLSLNESNGQLFLVVEDDGPGIAPDdieriFEPftqvnnqernsEKGHGLGLAIVKQITRWH 505
Cdd:COG3920 407 LVTNALKHAFLsgeggRIRVSWRREDGRLRLTVSDNGVGLPED-----VDP-----------PARKGLGLRLIRALVRQL 470
|
90 100
....*....|....*....|....*
gi 1841552669 506 QGKVRVKVNgsalGGACFELQWPKQ 530
Cdd:COG3920 471 GGTLELDRP----EGTRVRITFPLA 491
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
456-511 |
5.72e-03 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 39.27 E-value: 5.72e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1841552669 456 LVVEDDGPGIAPDDIERIFEPFTQVnnqeRNSEKGHGLGLAIVKQITRWHQGKVRV 511
Cdd:PRK13557 327 IAVTDTGSGMPPEILARVMDPFFTT----KEEGKGTGLGLSMVYGFAKQSGGAVRI 378
|
|
| PRK14868 |
PRK14868 |
DNA topoisomerase VI subunit B; Provisional |
422-474 |
5.97e-03 |
|
DNA topoisomerase VI subunit B; Provisional
Pssm-ID: 237842 [Multi-domain] Cd Length: 795 Bit Score: 39.40 E-value: 5.97e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1841552669 422 RALLRAVKNLLSNAARFAQQ-----EIHLSLNESNGQLFLVVEDDGPGIAPDDIERIF 474
Cdd:PRK14868 45 RGLVTAVKEAVDNALDATEEagilpDIYVEIEEVGDYYRLVVEDNGPGITKEQIPKVF 102
|
|
| |
