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Conserved domains on  [gi|1834229548|ref|WP_168758012|]
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ABC transporter ATP-binding protein [Pseudomonas umsongensis]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467929)

ABC transporter ATP-binding protein similar to the ATPase subunits (GsiA and OppF) of complexes which are responsible for coupling the energy of ATP hydrolysis to the import of glutathione or oligopeptides

CATH:  3.40.50.300
Gene Ontology:  GO:0042626|GO:0140359|GO:0016887|GO:0005524
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-532 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 978.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlARHPSGTIEYSGQNLL 80
Cdd:COG4172     1 MMSMPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDP-AAHPSGSILFDGQDLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSG 160
Cdd:COG4172    80 GLSERELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 161 GQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQA 240
Cdd:COG4172   160 GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 241 SCEQLFRAPQHPYTRELLAAEPSGTPA-TNVVGPPMLTVEDLKVWFPIKKGLLKKTVDYVKAVDGINFSLPQGQTLGIVG 319
Cdd:COG4172   240 PTAELFAAPQHPYTRKLLAAEPRGDPRpVPPDAPPLLEARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 320 ESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMG-TEA 398
Cdd:COG4172   320 ESGSGKSTLGLALLRLIPSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPFGSLSPRMTVGQIIAEGLRVHGPGlSAA 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 399 EQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTY 478
Cdd:COG4172   400 ERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAY 479

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 479 LFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAFLVP 532
Cdd:COG4172   480 LFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
 
Name Accession Description Interval E-value
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-532 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 978.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlARHPSGTIEYSGQNLL 80
Cdd:COG4172     1 MMSMPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDP-AAHPSGSILFDGQDLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSG 160
Cdd:COG4172    80 GLSERELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 161 GQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQA 240
Cdd:COG4172   160 GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 241 SCEQLFRAPQHPYTRELLAAEPSGTPA-TNVVGPPMLTVEDLKVWFPIKKGLLKKTVDYVKAVDGINFSLPQGQTLGIVG 319
Cdd:COG4172   240 PTAELFAAPQHPYTRKLLAAEPRGDPRpVPPDAPPLLEARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 320 ESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMG-TEA 398
Cdd:COG4172   320 ESGSGKSTLGLALLRLIPSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPFGSLSPRMTVGQIIAEGLRVHGPGlSAA 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 399 EQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTY 478
Cdd:COG4172   400 ERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAY 479

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 479 LFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAFLVP 532
Cdd:COG4172   480 LFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 6-528 0e+00

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 719.18  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNLLNLKEK 85
Cdd:PRK15134    5 LLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPPVVYPSGDIRFHGESLLHASEQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSGGQRQR 165
Cdd:PRK15134   85 TLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGGERQR 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:PRK15134  165 VMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 246 FRAPQHPYTRELLAAEPSGTP-ATNVVGPPMLTVEDLKVWFPIKKGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSG 324
Cdd:PRK15134  245 FSAPTHPYTQKLLNSEPSGDPvPLPEPASPLLDVEQLQVAFPIRKGILKRTVDHNVVVKNISFTLRPGETLGLVGESGSG 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 325 KSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIH-KMGTEAEQEQA 403
Cdd:PRK15134  325 KSTTGLALLRLINSQGEIWFDGQPLHNLNRRQLLPVRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHqPTLSAAQREQQ 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 404 IIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISH 483
Cdd:PRK15134  405 VIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISH 484

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 484 DLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAA 528
Cdd:PRK15134  485 DLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLLALS 529
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 275-507 6.79e-107

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 319.07  E-value: 6.79e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLT 353
Cdd:cd03257     1 LLEVKNLSVSFPTGGG-------SVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGsIIFDGKDLLKLS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGT-EAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQR 432
Cdd:cd03257    74 RRLRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSkKEARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQR 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 433 IAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03257   154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 302-527 1.32e-62

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 206.19  E-value: 1.32e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMC 380
Cdd:TIGR02769  27 LTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKpAQGTVSFRGQDLYQLDRKQRRAFRRDVQLVFQDSPSAVNPRMT 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQ 460
Cdd:TIGR02769 107 VRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNLDMVLQ 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 461 RQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAApQHPYTQQLLEA 527
Cdd:TIGR02769 187 AVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLLSF-KHPAGRNLQSA 252
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 302-453 1.42e-39

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 140.86  E-value: 1.42e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLdslTQQQVRPLRREMQVVFQDPFgsLSPRMC 380
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLsPTEGTILLDGQDL---TDDERKSLRKEIGYVFQDPQ--LFPRLT 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 381 VSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGL--DPETR-HRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:pfam00005  76 VRENLRLGLLLKGLSKREKDARAE-EALEKLGLgdLADRPvGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
GguA NF040905
sugar ABC transporter ATP-binding protein;
29-456 4.33e-26

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 111.42  E-value: 4.33e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvTAHSILRllpyplARHPSGTieYSGQNLLNLKEKTIRHIRGNR---IAMIFQEpmTS 105
Cdd:NF040905   20 VNLSVREGEIHALCGENGAGKS-TLMKVLS------GVYPHGS--YEGEILFDGEVCRFKDIRDSEalgIVIIHQE--LA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LNPLHSIEKQI---NEVLgiHKGLIGKVAT-KRTLELLEMVGIPE-PEKRLKalphELSGGQRQRVMIAMALANEPELLI 180
Cdd:NF040905   89 LIPYLSIAENIflgNERA--KRGVIDWNETnRRARELLAKVGLDEsPDTLVT----DIGVGKQQLVEIAKALSKDVKLLI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 181 ADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF----RAPQHPYTRE 256
Cdd:NF040905  163 LDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTIETLDCRADEvtedRIIRGMVGRD 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 257 LLAAEPSGTPAtnvVGPPMLTVEDLKVWFPIKKGLlkktvdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAIL-RL 335
Cdd:NF040905  242 LEDRYPERTPK---IGEVVFEVKNWTVYHPLHPER--------KVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFgRS 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 336 IGSK--GGIRFEGKQLDSLTQQQ--------VRPLRREMQVVFQDP---------FGSLSPRMCVSQI----VGEGLRiH 392
Cdd:NF040905  311 YGRNisGTVFKDGKEVDVSTVSDaidaglayVTEDRKGYGLNLIDDikrnitlanLGKVSRRGVIDENeeikVAEEYR-K 389

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 393 KMGTEAEQEQAIIAALkevgldpetrhryphefSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:NF040905  390 KMNIKTPSVFQKVGNL-----------------SGGNQQKVVLSKWLFTDPDVLILDEPTRGID 436
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
301-496 1.05e-18

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 84.21  E-value: 1.05e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTL--GLA-ILRLIGskGGIRFEGKQLDSLTQQQVR-----PLRremqvvfqdpf 372
Cdd:NF040873    7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLlkVLAgVLRPTS--GTVRRAGGARVAYVPQRSEvpdslPLT----------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 gslsprmcVSQIVGEGLRIHKMGT---EAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:NF040873   74 --------VRDLVAMGRWARRGLWrrlTRDDRAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEADLLLLD 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLM 496
Cdd:NF040873  145 EPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCVL 190
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
23-228 1.31e-18

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 83.82  E-value: 1.31e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhPSgtieySGqnllnlkekTIRHIRGNRIAMIFQE- 101
Cdd:NF040873    5 RPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLR------PT-----SG---------TVRRAGGARVAYVPQRs 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 ------PMTslnplhsiekqINEVLGI----HKGLIGKV---ATKRTLELLEMVGIPEPEKRlkALpHELSGGQRQRVMI 168
Cdd:NF040873   65 evpdslPLT-----------VRDLVAMgrwaRRGLWRRLtrdDRAAVDDALERVGLADLAGR--QL-GELSGGQRQRALL 130

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 169 AMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRV 228
Cdd:NF040873  131 AQGLAQEADLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
289-512 3.70e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 67.84  E-value: 3.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 289 KGLLKKTVDyVKAVDGINFSLPQGQTLGIVGESGSGKSTlGLAILRLIGSKGGIRfeGKQLDSLTQQQvRPLRREM---Q 365
Cdd:NF000106   17 RGLVKHFGE-VKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGRR--PWRF*TWCANR-RALRRTIg*hR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 366 VVFQDPFGSLSPRMCVsQIVGEGLRIHKMGTEAEQEQAiiaaLKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPAL 445
Cdd:NF000106   92 PVR*GRRESFSGRENL-YMIGR*LDLSRKDARARADEL----LERFSLT-EAAGRAAAKYSGGMRRRLDLAASMIGRPAV 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:NF000106  166 LYLDEPTTGLDPRTRNEVWDEVRSM-VRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
GguA NF040905
sugar ABC transporter ATP-binding protein;
294-505 3.97e-10

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 62.11  E-value: 3.97e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 294 KTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLI---GS-KGGIRFEGKQldsltqQQVRPLR----REMQ 365
Cdd:NF040905    9 KTFPGVKALDDVNLSVREGEIHALCGENGAGKSTL-MKVLSGVyphGSyEGEILFDGEV------CRFKDIRdseaLGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 366 VVFQDPfgSLSPRMCVSQIVGEGLRIHKMG----TEAEQEQAiiAALKEVGLD--PETRhryPHEFSGGQRQRIAIARAL 439
Cdd:NF040905   82 IIHQEL--ALIPYLSIAENIFLGNERAKRGvidwNETNRRAR--ELLAKVGLDesPDTL---VTDIGVGKQQLVEIAKAL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 440 VLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVE 505
Cdd:NF040905  155 SKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTIE 219
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
5-245 5.84e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 60.90  E-value: 5.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSVTAhsilrlLPYPLARHPSGTIEYSGQNLLNLKE 84
Cdd:NF000106   12 NAVEVRGLVKHF--GE--VKAVDGVDLDVREGTVLGVLGP*GAA**RGA------LPAHV*GPDAGRRPWRF*TWCANRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KTIRHIRGNR-IAMIFQEPMTSLNPLHSIEKQINevlgihkgLIGKVATKRTLELLEMVGIPEPEKRLKAlphELSGGQR 163
Cdd:NF000106   82 ALRRTIG*HRpVR*GRRESFSGRENLYMIGR*LD--------LSRKDARARADELLERFSLTEAAGRAAA---KYSGGMR 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQlKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCE 243
Cdd:NF000106  151 RRLDLAASMIGRPAVLYLDEPTTGLDPRTR-NEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVD 229


                  ..
gi 1834229548 244 QL 245
Cdd:NF000106  230 EL 231
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 311-484 2.63e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.84  E-value: 2.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  311 QGQTLGIVGESGSGKSTLGLAILRLIGSKGGirfegkqldsltqqqvrplrremQVVFQDPfgslsprmcvsqivgeglr 390
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGG-----------------------GVIYIDG------------------- 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  391 ihkmgteaeqeqAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRS- 469
Cdd:smart00382  39 ------------EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELr 106

                          170
                   ....*....|....*....
gi 1834229548  470 ----LQSKYNLTYLFISHD 484
Cdd:smart00382 107 llllLKSEKNLTVILTTND 125
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
158-456 6.80e-08

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 55.52  E-value: 6.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALD-----------VTVQlkilellkelQARLGMALLLISHDLNLVKRIAH 226
Cdd:NF033858  137 LSGGMKQKLGLCCALIHDPDLLILDEPTTGVDplsrrqfweliDRIR----------AERPGMSVLVATAYMEEAERFDW 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 227 RVcVMQRGCIVEQASCEQLFRAPQHP-----YTReLLAAEPSGTPATNVVGPPMLTVEDLKVwfpIK-KGLLKKTVDYVk 300
Cdd:NF033858  207 LV-AMDAGRVLATGTPAELLARTGADtleaaFIA-LLPEEKRRGHQPVVIPPRPADDDDEPA---IEaRGLTMRFGDFT- 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQLDSltqqqvrplrremqvvfqdpfGSL 375
Cdd:NF033858  281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTmkmltGL----LPASEGEAWLFGQPVDA---------------------GDI 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SPRMCV---SQ--------IVGEGLRIH----KMGtEAEQEQAIIAALKEVGLDPETRHRyPHEFSGGQRQRIAIARALV 440
Cdd:NF033858  336 ATRRRVgymSQafslygelTVRQNLELHarlfHLP-AAEIAARVAEMLERFDLADVADAL-PDSLPLGIRQRLSLAVAVI 413

                         330
                  ....*....|....*.
gi 1834229548 441 LKPALILLDEPTSALD 456
Cdd:NF033858  414 HKPELLILDEPTSGVD 429
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-248 2.45e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 50.17  E-value: 2.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEF-VVGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIL-RllPYplARHPSGTIeysgqnLLN 81
Cdd:NF040905  255 EVVFEVKNWTVYHpLHPER--KVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFgR--SY--GRNISGTV------FKD 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHIR---GNRIA----------MIFQEPM---TSLNPLHSIEKQ--INEVLGIhkgligKVATK-------RTL 136
Cdd:NF040905  323 GKEVDVSTVSdaiDAGLAyvtedrkgygLNLIDDIkrnITLANLGKVSRRgvIDENEEI------KVAEEyrkkmniKTP 396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 137 ELLEMVGipepekrlkalphELSGGQRQRVMIAMALANEPELLIADEPTTALDV-------TVqlkilellKELQARLGM 209
Cdd:NF040905  397 SVFQKVG-------------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVgakyeiyTI--------INELAAEGK 455

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1834229548 210 ALLLISHDLNLVKRIAHRVCVMQRGCIV-----EQASCEQLFRA 248
Cdd:NF040905  456 GVIVISSELPELLGMCDRIYVMNEGRITgelprEEASQERIMRL 499
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
153-189 1.56e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 44.73  E-value: 1.56e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1834229548 153 ALPHELSGGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:NF033858  393 ALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
299-472 9.60e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 42.03  E-value: 9.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-GSK----GGIR-FEGKQLDSLTQQQVRPlrremQVVFQdPF 372
Cdd:NF033858   14 TVALDDVSLDIPAGCMVGLIGPDGVGKSSL----LSLIaGARkiqqGRVEvLGGDMADARHRRAVCP-----RIAYM-PQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 G-------SLSprmcvsqiVGEGLRIHkmGT-----EAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALV 440
Cdd:NF033858   84 GlgknlypTLS--------VFENLDFF--GRlfgqdAAERRRRIDELLRATGLAP-FADRPAGKLSGGMKQKLGLCCALI 152

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1834229548 441 LKPALILLDEPTSALDRTVQRQVVELLRSLQS 472
Cdd:NF033858  153 HDPDLLILDEPTTGVDPLSRRQFWELIDRIRA 184
 
Name Accession Description Interval E-value
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-532 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 978.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlARHPSGTIEYSGQNLL 80
Cdd:COG4172     1 MMSMPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDP-AAHPSGSILFDGQDLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSG 160
Cdd:COG4172    80 GLSERELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 161 GQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQA 240
Cdd:COG4172   160 GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 241 SCEQLFRAPQHPYTRELLAAEPSGTPA-TNVVGPPMLTVEDLKVWFPIKKGLLKKTVDYVKAVDGINFSLPQGQTLGIVG 319
Cdd:COG4172   240 PTAELFAAPQHPYTRKLLAAEPRGDPRpVPPDAPPLLEARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 320 ESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMG-TEA 398
Cdd:COG4172   320 ESGSGKSTLGLALLRLIPSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPFGSLSPRMTVGQIIAEGLRVHGPGlSAA 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 399 EQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTY 478
Cdd:COG4172   400 ERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAY 479

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 479 LFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAFLVP 532
Cdd:COG4172   480 LFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 6-528 0e+00

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 719.18  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNLLNLKEK 85
Cdd:PRK15134    5 LLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPPVVYPSGDIRFHGESLLHASEQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSGGQRQR 165
Cdd:PRK15134   85 TLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGGERQR 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:PRK15134  165 VMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 246 FRAPQHPYTRELLAAEPSGTP-ATNVVGPPMLTVEDLKVWFPIKKGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSG 324
Cdd:PRK15134  245 FSAPTHPYTQKLLNSEPSGDPvPLPEPASPLLDVEQLQVAFPIRKGILKRTVDHNVVVKNISFTLRPGETLGLVGESGSG 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 325 KSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIH-KMGTEAEQEQA 403
Cdd:PRK15134  325 KSTTGLALLRLINSQGEIWFDGQPLHNLNRRQLLPVRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHqPTLSAAQREQQ 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 404 IIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISH 483
Cdd:PRK15134  405 VIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISH 484

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 484 DLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAA 528
Cdd:PRK15134  485 DLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLLALS 529
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 4-528 0e+00

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 643.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLarHPSGTIEYSGQNLLNLK 83
Cdd:COG1123     2 TPLLEVRDLSVRYPGGDV--PAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGG--RISGEVLLDGRDLLELS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EktirHIRGNRIAMIFQEPMTSLNPLhSIEKQINEVLGIHkGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQR 163
Cdd:COG1123    78 E----ALRGRRIGMVFQDPMTQLNPV-TVGDQIAEALENL-GLSRAEARARVLELLEAVGL---ERRLDRYPHQLSGGQR 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCE 243
Cdd:COG1123   149 QRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPE 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 244 QLFRAPQHPYTRELLAAEPSGTPATNVVGPPMLTVEDLKVWFPIKKGllkktvDYVKAVDGINFSLPQGQTLGIVGESGS 323
Cdd:COG1123   229 EILAAPQALAAVPRLGAARGRAAPAAAAAEPLLEVRNLSKRYPVRGK------GGVRAVDDVSLTLRRGETLGLVGESGS 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 324 GKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQ 402
Cdd:COG1123   303 GKSTLARLLLGLLRpTSGSILFDGKDLTKLSRRSLRELRRRVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRE 382

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 403 AIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFIS 482
Cdd:COG1123   383 RVAELLERVGLPPDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFIS 462

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 1834229548 483 HDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAA 528
Cdd:COG1123   463 HDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQHPYTRALLAAV 508
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 1-527 4.45e-163

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 477.04  E-value: 4.45e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQN-- 78
Cdd:PRK10261    7 LDARDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSrq 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 ---LLNLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALP 155
Cdd:PRK10261   87 vieLSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILSRYP 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGC 235
Cdd:PRK10261  167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGE 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 236 IVEQASCEQLFRAPQHPYTRELLAA---------------------------EPSGTPATNVVGPPMLTVEDLKVWFPIK 288
Cdd:PRK10261  247 AVETGSVEQIFHAPQHPYTRALLAAvpqlgamkgldyprrfplislehpakqEPPIEQDTVVDGEPILQVRNLVTRFPLR 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 289 KGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQVRPLRREMQVV 367
Cdd:PRK10261  327 SGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGeIIFNGQRIDTLSPGKLQALRRDIQFI 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 368 FQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALIL 447
Cdd:PRK10261  407 FQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVII 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 448 LDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEA 527
Cdd:PRK10261  487 ADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLMAA 566
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 274-528 7.49e-136

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 396.79  E-value: 7.49e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPIKKGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSL 352
Cdd:COG4608     6 PLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEpTSGEILFDGQDITGL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 353 TQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQR 432
Cdd:COG4608    86 SGRELRPLRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFSGGQRQR 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 433 IAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:COG4608   166 IGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDEL 245

                         250
                  ....*....|....*.
gi 1834229548 513 FAAPQHPYTQQLLEAA 528
Cdd:COG4608   246 YARPLHPYTQALLSAV 261
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 6-266 3.93e-134

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 392.11  E-value: 3.93e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLarHPSGTIEYSGQNLLNLKEK 85
Cdd:COG0444     1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG--ITSGEILFDGEDLLKLSEK 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSGGQRQR 165
Cdd:COG0444    79 ELRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQR 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:COG0444   159 VMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEEL 238

                         250       260
                  ....*....|....*....|.
gi 1834229548 246 FRAPQHPYTRELLAAEPSGTP 266
Cdd:COG0444   239 FENPRHPYTRALLSSIPRLDP 259
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 275-527 2.99e-122

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 361.68  E-value: 2.99e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI----GSKGGIRFEGKQLD 350
Cdd:COG0444     1 LLEVRNLKVYFPTRRG-------VVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLpppgITSGEILFDGEDLL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 351 SLTQQQVRPLR-REMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGL-DPETR-HRYPHEFSG 427
Cdd:COG0444    74 KLSEKELRKIRgREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLpDPERRlDRYPHELSG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 428 GQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:COG0444   154 GMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEG 233

                         250       260
                  ....*....|....*....|
gi 1834229548 508 DAQSIFAAPQHPYTQQLLEA 527
Cdd:COG0444   234 PVEELFENPRHPYTRALLSS 253
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 275-507 6.79e-107

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 319.07  E-value: 6.79e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLT 353
Cdd:cd03257     1 LLEVKNLSVSFPTGGG-------SVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGsIIFDGKDLLKLS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGT-EAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQR 432
Cdd:cd03257    74 RRLRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSkKEARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQR 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 433 IAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03257   154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 275-529 3.20e-103

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 310.20  E-value: 3.20e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGLlkktvdyVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKqldSLT 353
Cdd:COG1124     1 MLEVRNLSVSYGQGGRR-------VPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLErPWSGEVTFDGR---PVT 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGteaEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRI 433
Cdd:COG1124    71 RRRRKAFRRRVQMVFQDPYASLHPRHTVDRILAEPLRIHGLP---DREERIAELLEQVGLPPSFLDRYPHQLSGGQRQRV 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 434 AIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIF 513
Cdd:COG1124   148 AIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227

                         250
                  ....*....|....*.
gi 1834229548 514 AAPQHPYTQQLLEAAF 529
Cdd:COG1124   228 AGPKHPYTRELLAASL 243
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 6-240 8.37e-103

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 308.28  E-value: 8.37e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplarHP-SGTIEYSGQNLLNLKE 84
Cdd:cd03257     1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLL------KPtSGSIIFDGKDLLKLSR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KtIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKvATKRTLELLEMVGIPEPEKRLKALPHELSGGQRQ 164
Cdd:cd03257    75 R-LRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKK-EARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQ 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQA 240
Cdd:cd03257   153 RVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 6-267 7.37e-99

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 308.37  E-value: 7.37e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVV-GERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLK 83
Cdd:COG1123   260 LLEVRNLSKRYPVrGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLR------PtSGSILFDGKDLTKLS 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRGnRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEpeKRLKALPHELSGGQR 163
Cdd:COG1123   334 RRSLRELRR-RVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPP--DLADRYPHELSGGQR 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCE 243
Cdd:COG1123   411 QRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTE 490

                         250       260
                  ....*....|....*....|....
gi 1834229548 244 QLFRAPQHPYTRELLAAEPSGTPA 267
Cdd:COG1123   491 EVFANPQHPYTRALLAAVPSLDPA 514
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 272-528 1.16e-94

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 291.10  E-value: 1.16e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 272 GPPMLTVEDLKVWFPIKKGLLKKTvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAiLRLIG--SKGGIRFEGKQL 349
Cdd:PRK11308    2 QQPLLQAIDLKKHYPVKRGLFKPE-RLVKALDGVSFTLERGKTLAVVGESGCGKSTLARL-LTMIEtpTGGELYYQGQDL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQ 429
Cdd:PRK11308   80 LKADPEAQKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSGGQ 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:PRK11308  160 RQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTK 239

                         250
                  ....*....|....*....
gi 1834229548 510 QSIFAAPQHPYTQQLLEAA 528
Cdd:PRK11308  240 EQIFNNPRHPYTQALLSAT 258
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 274-532 2.24e-88

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 275.05  E-value: 2.24e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPIKKGLL-----KKTVdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGK 347
Cdd:PRK15079    7 VLLEVADLKVHFDIKDGKQwfwqpPKTL---KAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGeVAWLGK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 348 QLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIVGEGLRIH--KMgTEAEQEQAIIAALKEVGLDPETRHRYPHEF 425
Cdd:PRK15079   84 DLLGMKDDEWRAVRSDIQMIFQDPLASLNPRMTIGEIIAEPLRTYhpKL-SRQEVKDRVKAMMLKVGLLPNLINRYPHEF 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 426 SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVE 505
Cdd:PRK15079  163 SGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVE 242

                         250       260
                  ....*....|....*....|....*..
gi 1834229548 506 QGDAQSIFAAPQHPYTQQLLEAaflVP 532
Cdd:PRK15079  243 LGTYDEVYHNPLHPYTKALMSA---VP 266
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 1-267 3.42e-88

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 274.69  E-value: 3.42e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVV-----GERCQRV--VEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTI 72
Cdd:COG4608     2 AMAEPLLEVRDLKKHFPVrgglfGRTVGVVkaVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEE------PtSGEI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  73 EYSGQNLLNLKEKTIRHIRgNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPePEkRLK 152
Cdd:COG4608    76 LFDGQDITGLSGRELRPLR-RRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLR-PE-HAD 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 153 ALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:COG4608   153 RYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMY 232

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1834229548 233 RGCIVEQASCEQLFRAPQHPYTRELLAAEPSGTPA 267
Cdd:COG4608   233 LGKIVEIAPRDELYARPLHPYTQALLSAVPVPDPE 267
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 6-262 7.93e-84

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 263.14  E-value: 7.93e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlARHPSGTIEYSGQNLLNLKEK 85
Cdd:PRK11022    3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYP-GRVMAEKLEFNGQDLQRISEK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSGGQRQR 165
Cdd:PRK11022   82 ERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:PRK11022  162 VMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDI 241

                         250
                  ....*....|....*..
gi 1834229548 246 FRAPQHPYTRELLAAEP 262
Cdd:PRK11022  242 FRAPRHPYTQALLRALP 258
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 2-262 1.59e-83

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 262.74  E-value: 1.59e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplAR--HPSGTIEYSGQNL 79
Cdd:PRK09473    8 QADALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLL----AAngRIGGSATFNGREI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  80 LNLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELS 159
Cdd:PRK09473   84 LNLPEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPHEFS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ 239
Cdd:PRK09473  164 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 243

                         250       260
                  ....*....|....*....|...
gi 1834229548 240 ASCEQLFRAPQHPYTRELLAAEP 262
Cdd:PRK09473  244 GNARDVFYQPSHPYSIGLLNAVP 266
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 6-260 4.73e-80

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 250.49  E-value: 4.73e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLlnlKEK 85
Cdd:COG1124     1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKS----TLLRALA-GLERPWSGEVTFDGRPV---TRR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGnRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLigkVATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQR 165
Cdd:COG1124    73 RRKAFRR-RVQMVFQDPYASLHPRHTVDRILAEPLRIHGLP---DREERIAELLEQVGLPP--SFLDRYPHQLSGGQRQR 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:COG1124   147 VAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADL 226

                         250
                  ....*....|....*
gi 1834229548 246 FRAPQHPYTRELLAA 260
Cdd:COG1124   227 LAGPKHPYTRELLAA 241
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
274-529 4.14e-77

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 243.59  E-value: 4.14e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPIKKGLLKKTvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSL 352
Cdd:COG4167     3 ALLEVRNLSKTFKYRTGLFRRQ--QFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGeILINGHKLEYG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 353 -TQQQVRPLRreMqvVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQ 431
Cdd:COG4167    81 dYKYRCKHIR--M--IFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLLPEHANFYPHMLSSGQKQ 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 432 RIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQS 511
Cdd:COG4167   157 RVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAE 236

                         250
                  ....*....|....*...
gi 1834229548 512 IFAAPQHPYTQQLLEAAF 529
Cdd:COG4167   237 VFANPQHEVTKRLIESHF 254
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 265-527 3.85e-73

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 235.77  E-value: 3.85e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 265 TPATNVVGPPMLTVEDLKVWFPIKKGLlkktvdyVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGI-- 342
Cdd:PRK09473    2 VPLAQQQADALLDVKDLRVTFSTPDGD-------VTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIgg 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 343 --RFEGKQLDSLTQQQVRPLRRE-MQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLdPETRH 419
Cdd:PRK09473   75 saTFNGREILNLPEKELNKLRAEqISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKM-PEARK 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 420 R---YPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLM 496
Cdd:PRK09473  154 RmkmYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVL 233

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1834229548 497 VVKQGQVVEQGDAQSIFAAPQHPYTQQLLEA 527
Cdd:PRK09473  234 VMYAGRTMEYGNARDVFYQPSHPYSIGLLNA 264
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
5-263 5.69e-65

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 214.38  E-value: 5.69e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhPSGTIE-----YSGQNL 79
Cdd:COG4170     2 PLLDIRNLTIEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITK------DNWHVTadrfrWNGIDL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  80 LNLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVL--GIHKGLIGKVAT---KRTLELLEMVGIPEPEKRLKAL 154
Cdd:COG4170    76 LKLSPRERRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEAIpsWTFKGKWWQRFKwrkKRAIELLHRVGIKDHKDIMNSY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQlkilellkeLQ-----ARL----GMALLLISHDLNLVKRIA 225
Cdd:COG4170   156 PHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQ---------AQifrllARLnqlqGTSILLISHDLESISQWA 226

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1834229548 226 HRVCVMQRGCIVEQASCEQLFRAPQHPYTRELLAAEPS 263
Cdd:COG4170   227 DTITVLYCGQTVESGPTEQILKSPHHPYTKALLRSMPD 264
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 275-527 1.58e-64

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 213.06  E-value: 1.58e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGLLKktvdyvkAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGI-----RFEGKQL 349
Cdd:PRK11022    3 LLNVDKLSVHFGDESAPFR-------AVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVmaeklEFNGQDL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQQQVRPL-RREMQVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGL-DPETR-HRYPHEFS 426
Cdd:PRK11022   76 QRISEKERRNLvGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIpDPASRlDVYPHQLS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 427 GGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQ 506
Cdd:PRK11022  156 GGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVET 235

                         250       260
                  ....*....|....*....|.
gi 1834229548 507 GDAQSIFAAPQHPYTQQLLEA 527
Cdd:PRK11022  236 GKAHDIFRAPRHPYTQALLRA 256
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 3-267 3.27e-63

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 209.82  E-value: 3.27e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   3 QDNLIEVRDLAVEFVV------GERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAhsilRLLPypLARHP-SGTIEYS 75
Cdd:PRK11308    2 QQPLLQAIDLKKHYPVkrglfkPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLA----RLLT--MIETPtGGELYYQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  76 GQNLLNlKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGI-PEPEKRLkal 154
Cdd:PRK11308   76 GQDLLK-ADPEAQKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLrPEHYDRY--- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:PRK11308  152 PHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLG 231

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1834229548 235 CIVEQASCEQLFRAPQHPYTRELLAAEPSGTPA 267
Cdd:PRK11308  232 RCVEKGTKEQIFNNPRHPYTQALLSATPRLNPD 264
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 302-527 1.32e-62

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 206.19  E-value: 1.32e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMC 380
Cdd:TIGR02769  27 LTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKpAQGTVSFRGQDLYQLDRKQRRAFRRDVQLVFQDSPSAVNPRMT 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQ 460
Cdd:TIGR02769 107 VRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNLDMVLQ 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 461 RQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAApQHPYTQQLLEA 527
Cdd:TIGR02769 187 AVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLLSF-KHPAGRNLQSA 252
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 272-525 7.18e-62

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 203.29  E-value: 7.18e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 272 GPPMLTVEDLKVWFpikkGllKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEG 346
Cdd:COG1127     2 SEPMIEVRNLTKSF----G--DRVV-----LDGVSLDVPRGEILAIIGGSGSGKSVL----LKLIIgllrpDSGEILVDG 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 347 KQLDSLTQQQVRPLRREMQVVFQDP--FGSLSprmcvsqiVGE----GLRIHKMGTEAEQEQAIIAALKEVGLdPETRHR 420
Cdd:COG1127    67 QDITGLSEKELYELRRRIGMLFQGGalFDSLT--------VFEnvafPLREHTDLSEAEIRELVLEKLELVGL-PGAADK 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 421 YPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQ 500
Cdd:COG1127   138 MPSELSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLAD 217

                         250       260
                  ....*....|....*....|....*
gi 1834229548 501 GQVVEQGDAQSIFAAPqHPYTQQLL 525
Cdd:COG1127   218 GKIIAEGTPEELLASD-DPWVRQFL 241
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 1-262 2.33e-61

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 204.94  E-value: 2.33e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDN--LIEVRDLAVEFVVGERCQ---------RVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarHPS 69
Cdd:PRK15079    1 VTEGKkvLLEVADLKVHFDIKDGKQwfwqppktlKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVK-----ATD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  70 GTIEYSGQNLLNLKEKTIRHIRgNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATK-RTLELLEMVGI-PEP 147
Cdd:PRK15079   76 GEVAWLGKDLLGMKDDEWRAVR-SDIQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKLSRQEVKdRVKAMMLKVGLlPNL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 148 EKRLkalPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHR 227
Cdd:PRK15079  155 INRY---PHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDR 231

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1834229548 228 VCVMQRGCIVEQASCEQLFRAPQHPYTRELLAAEP 262
Cdd:PRK15079  232 VLVMYLGHAVELGTYDEVYHNPLHPYTKALMSAVP 266
PhnK COG4107
ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ...
 269-524 8.25e-60

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];


Pssm-ID: 443283 [Multi-domain]  Cd Length: 262  Bit Score: 198.50  E-value: 8.25e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 269 NVVGPPMLTVEDLKVWFpikkgllKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAI-LRLIGSKGGIRF--- 344
Cdd:COG4107     2 TNEEQPLLSVRGLSKRY-------GPGCGTVVACRDVSFDLYPGEVLGIVGESGSGKSTLLKCLyFDLAPTSGSVYYrdr 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 345 EGKQLD--SLTQQQVRPLRR-EMQVVFQDPFGSLspRMCVSQI--VGEGL------RIHKMGTEAEQeqaiiaALKEVGL 413
Cdd:COG4107    75 DGGPRDlfALSEAERRRLRRtDWGMVYQNPRDGL--RMDVSAGgnIAERLmaagerHYGDIRARALE------WLERVEI 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 414 DPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSH 493
Cdd:COG4107   147 PLERIDDLPRTFSGGMQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLAD 226

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1834229548 494 QLMVVKQGQVVEQGDAQSIFAAPQHPYTQQL 524
Cdd:COG4107   227 RTMVMKNGRVVESGLTDQVLEDPQHPYTQLL 257
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 303-523 1.85e-58

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 193.87  E-value: 1.85e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDP--FGSL 375
Cdd:cd03261    17 KGVDLDVRRGEILAIIGPSGSGKSTL----LRLIVgllrpDSGEVLIDGEDISGLSEAELYRLRRRMGMLFQSGalFDSL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SprmcVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLdPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:cd03261    93 T----VFENVAFPLREHTRLSEEEIREIVLEKLEAVGL-RGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGL 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAApQHPYTQQ 523
Cdd:cd03261   168 DPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRAS-DDPLVRQ 234
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 6-267 2.82e-58

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 204.32  E-value: 2.82e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVG----ERCQR---VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQN 78
Cdd:PRK10261  313 ILQVRNLVTRFPLRsgllNRVTRevhAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLV-----ESQGGEIIFNGQR 387

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 LLNLKEKTIRHIRGNrIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIpEPEKRLKaLPHEL 158
Cdd:PRK10261  388 IDTLSPGKLQALRRD-IQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGL-LPEHAWR-YPHEF 464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVE 238
Cdd:PRK10261  465 SGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVE 544

                         250       260
                  ....*....|....*....|....*....
gi 1834229548 239 QASCEQLFRAPQHPYTRELLAAEPSGTPA 267
Cdd:PRK10261  545 IGPRRAVFENPQHPYTRKLMAAVPVADPS 573
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
275-525 1.41e-57

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 195.30  E-value: 1.41e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGLlkktvdyVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQL 349
Cdd:COG1135     1 MIELENLSKTFPTKGGP-------VTALDDVSLTIEKGEIFGIIGYSGAGKSTL----IRCINllerpTSGSVLVDGVDL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQQQVRPLRREMQVVFQDpFGSLSPRMcVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQ 429
Cdd:COG1135    70 TALSERELRAARRKIGMIFQH-FNLLSSRT-VAENVALPLEIAGV-PKAEIRKRVAELLELVGLS-DKADAYPSQLSGGQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:COG1135   146 KQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPV 225

                         250
                  ....*....|....*.
gi 1834229548 510 QSIFAAPQHPYTQQLL 525
Cdd:COG1135   226 LDVFANPQSELTRRFL 241
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 275-517 3.15e-57

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 190.87  E-value: 3.15e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQL 349
Cdd:cd03258     1 MIELKNVSKVFGDTGG-------KVTALKDVSLSVPKGEIFGIIGRSGAGKSTL----IRCINglerpTSGSVLVDGTDL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQQQVRPLRREMQVVFQDpFGSLSPRMcVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQ 429
Cdd:cd03258    70 TLLSGKELRKARRRIGMIFQH-FNLLSSRT-VFENVALPLEIAGVP-KAEIEERVLELLELVGLE-DKADAYPAQLSGGQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:cd03258   146 KQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTV 225


                  ....*...
gi 1834229548 510 QSIFAAPQ 517
Cdd:cd03258   226 EEVFANPQ 233
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 7-514 4.66e-56

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 196.18  E-value: 4.66e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHsILRLLP----------YPLARHPS------- 69
Cdd:TIGR03269   1 IEVKNLTKKF----DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMH-VLRGMDqyeptsgriiYHVALCEKcgyverp 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  70 -----------GTIEYSGQNLLNLKEKTIRHIRgNRIAMIFQEPMTslnpLHSIEKQINEVL-GIHK-GLIGKVATKRTL 136
Cdd:TIGR03269  76 skvgepcpvcgGTLEPEEVDFWNLSDKLRRRIR-KRIAIMLQRTFA----LYGDDTVLDNVLeALEEiGYEGKEAVGRAV 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 137 ELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISH 216
Cdd:TIGR03269 151 DLIEMVQL---SHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSH 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 217 DLNLVKRIAHRVCVMQRGCIVEQASCEQLfrapqhpyTRELLAAEPSGTPATNV-VGPPMLTVEDL-KVWFPIKKGLlkk 294
Cdd:TIGR03269 228 WPEVIEDLSDKAIWLENGEIKEEGTPDEV--------VAVFMEGVSEVEKECEVeVGEPIIKVRNVsKRYISVDRGV--- 296

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 295 tvdyVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFE-GKQLDSLTQQqvRPL-----RREMQVV 367
Cdd:TIGR03269 297 ----VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLePTSGEVNVRvGDEWVDMTKP--GPDgrgraKRYIGIL 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 368 FQDPfgSLSPRMCVSQIVGEGLRIhKMGTEAEQEQAIIaALKEVGLDPETR----HRYPHEFSGGQRQRIAIARALVLKP 443
Cdd:TIGR03269 371 HQEY--DLYPHRTVLDNLTEAIGL-ELPDELARMKAVI-TLKMVGFDEEKAeeilDKYPDELSEGERHRVALAQVLIKEP 446

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 444 ALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:TIGR03269 447 RIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIVE 517
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 26-260 4.95e-56

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 188.37  E-value: 4.95e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhpSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEPMTS 105
Cdd:PRK10418   19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILP-------AGVRQTAGRVLLDGKPVAPCALRGRKIATIMQNPRSA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LNPLHSIEKQINEVLGIhkglIGKVATKRTL-ELLEMVGIPEPEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEP 184
Cdd:PRK10418   92 FNPLHTMHTHARETCLA----LGKPADDATLtAALEAVGLENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEP 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 185 TTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELLAA 260
Cdd:PRK10418  168 TTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA 243
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 273-520 4.39e-55

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 189.15  E-value: 4.39e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKvwfpikkgllkKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGK 347
Cdd:COG3842     3 MPALELENVS-----------KRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTL----LRMIAgfetpDSGRILLDGR 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 348 QLDSltqqqVRPLRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSG 427
Cdd:COG3842    68 DVTG-----LPPEKRNVGMVFQDY--ALFPHLTVAENVAFGLRMRGVP-KAEIRARVAELLELVGLE-GLADRYPHQLSG 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 428 GQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:COG3842   139 GQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVG 218

                         250
                  ....*....|...
gi 1834229548 508 DAQSIFAAPQHPY 520
Cdd:COG3842   219 TPEEIYERPATRF 231
PhnK COG4107
ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ...
 6-260 8.24e-55

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];


Pssm-ID: 443283 [Multi-domain]  Cd Length: 262  Bit Score: 185.40  E-value: 8.24e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvGERCQRVV--EGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLARHpSGTIEYSG-----QN 78
Cdd:COG4107     8 LLSVRGLSKRY--GPGCGTVVacRDVSFDLYPGEVLGIVGESGSGKS----TLLKCLYFDLAPT-SGSVYYRDrdggpRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 LLNLKEKTIRHIRGNRIAMIFQEPMTSLNPLHS-----IEKQIneVLGI-HKGLIgkvaTKRTLELLEMVGIPEpeKRLK 152
Cdd:COG4107    81 LFALSEAERRRLRRTDWGMVYQNPRDGLRMDVSaggniAERLM--AAGErHYGDI----RARALEWLERVEIPL--ERID 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 153 ALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:COG4107   153 DLPRTFSGGMQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLADRTMVMK 232

                         250       260
                  ....*....|....*....|....*...
gi 1834229548 233 RGCIVEQASCEQLFRAPQHPYTRELLAA 260
Cdd:COG4107   233 NGRVVESGLTDQVLEDPQHPYTQLLVSS 260
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
275-535 1.38e-53

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 182.30  E-value: 1.38e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGLLKKtvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLD--- 350
Cdd:PRK15112    4 LLEVRNLSKTFRYRTGWFRR--QTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEpTSGELLIDDHPLHfgd 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 351 -SLTQQQVRplrremqVVFQDPFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQ 429
Cdd:PRK15112   82 ySYRSQRIR-------MIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQ 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:PRK15112  155 KQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGST 234

                         250       260
                  ....*....|....*....|....*.
gi 1834229548 510 QSIFAAPQHPYTQQLLEAAFLVPATA 535
Cdd:PRK15112  235 ADVLASPLHELTKRLIAGHFGEALTA 260
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
7-271 1.42e-53

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 184.51  E-value: 1.42e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:COG1135     2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKS----TLIRCINL-LERPTSGSVLVDGVDLTALSERE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGnRIAMIFQEP--MTSLN-------PLhsiekqinEVLGIHKGLIgkvaTKRTLELLEMVGIpepEKRLKALPHE 157
Cdd:COG1135    77 LRAARR-KIGMIFQHFnlLSSRTvaenvalPL--------EIAGVPKAEI----RKRVAELLELVGL---SDKADAYPSQ 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALD-------------VtvqlkilellkelQARLGMALLLISHDLNLVKRI 224
Cdd:COG1135   141 LSGGQKQRVGIARALANNPKVLLCDEATSALDpettrsildllkdI-------------NRELGLTIVLITHEMDVVRRI 207

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 225 AHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELLAAEPSGTPATNVV 271
Cdd:COG1135   208 CDRVAVLENGRIVEQGPVLDVFANPQSELTRRFLPTVLNDELPEELL 254
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
6-262 4.24e-53

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 183.08  E-value: 4.24e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLaRHPSGTIEYSGQNLLNLKEK 85
Cdd:PRK15093    3 LLDIRNLTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNW-RVTADRMRFDDIDLLRLSPR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLG--IHKGLIGKV---ATKRTLELLEMVGIPEPEKRLKALPHELSG 160
Cdd:PRK15093   82 ERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPgwTYKGRWWQRfgwRKRRAIELLHRVGIKDHKDAMRSFPYELTE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 161 GQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQA 240
Cdd:PRK15093  162 GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETA 241

                         250       260
                  ....*....|....*....|..
gi 1834229548 241 SCEQLFRAPQHPYTRELLAAEP 262
Cdd:PRK15093  242 PSKELVTTPHHPYTQALIRAIP 263
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
302-527 3.02e-52

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 178.73  E-value: 3.02e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMC 380
Cdd:PRK10419   28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESpSQGNVSWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAVNPRKT 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRiHKMG-TEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTV 459
Cdd:PRK10419  108 VREIIREPLR-HLLSlDKAERLARASEMLRAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVL 186

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 460 QRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQ---GDAQSIfaapQHPYTQQLLEA 527
Cdd:PRK10419  187 QAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETqpvGDKLTF----SSPAGRVLQNA 253
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 299-517 9.35e-52

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 175.98  E-value: 9.35e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDPFgslsp 377
Cdd:COG1122    14 TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLkPTSGEVLVDGK---DITKKNLRELRRKVGLVFQNPD----- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 rmcvSQIVGE--------GLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:COG1122    86 ----DQLFAPtveedvafGPENLGL-PREEIRERVEEALELVGLE-HLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:COG1122   160 EPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYE 226
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 6-250 2.23e-51

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 175.46  E-value: 2.23e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNLLNLKEK 85
Cdd:cd03258     1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKS----TLIRCING-LERPTSGSVLVDGTDLTLLSGK 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRgNRIAMIFQE--PMTSLNPLHSIEKQInEVLGIHKgligKVATKRTLELLEMVGIpepEKRLKALPHELSGGQR 163
Cdd:cd03258    76 ELRKAR-RRIGMIFQHfnLLSSRTVFENVALPL-EIAGVPK----AEIEERVLELLELVGL---EDKADAYPAQLSGGQK 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCE 243
Cdd:cd03258   147 QRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVE 226


                  ....*..
gi 1834229548 244 QLFRAPQ 250
Cdd:cd03258   227 EVFANPQ 233
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 6-259 4.87e-51

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 174.41  E-value: 4.87e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNLlNLKEK 85
Cdd:COG1126     1 MIEIENLHKSF--GD--LEVLKGISLDVEKGEVVVIIGPSGSGKS----TLLRCINL-LEEPDSGTITVDGEDL-TDSKK 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGnRIAMIFQE----P-MTSL-N----PLHsiekqineVLGIHKgligKVATKRTLELLEMVGIPEpekRLKALP 155
Cdd:COG1126    71 DINKLRR-KVGMVFQQfnlfPhLTVLeNvtlaPIK--------VKKMSK----AEAEERAMELLERVGLAD---KADAYP 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 HELSGGQRQRVMIAMALANEPELLIADEPTTALD---------VTVQLkilellkelqARLGMALLLISHDLNLVKRIAH 226
Cdd:COG1126   135 AQLSGGQQQRVAIARALAMEPKVMLFDEPTSALDpelvgevldVMRDL----------AKEGMTMVVVTHEMGFAREVAD 204

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1834229548 227 RVCVMQRGCIVEQASCEQLFRAPQHPYTRELLA 259
Cdd:COG1126   205 RVVFMDGGRIVEEGPPEEFFENPQHERTRAFLS 237
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 275-526 2.34e-50

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 172.87  E-value: 2.34e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFpikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQL 349
Cdd:COG1126     1 MIEIENLHKSF-----------GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTL----LRCINlleepDSGTITVDGEDL 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DsLTQQQVRPLRREMQVVFQDpFgSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLdPETRHRYPHEFSGGQ 429
Cdd:COG1126    66 T-DSKKDINKLRRKVGMVFQQ-F-NLFPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGL-ADKADAYPAQLSGGQ 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALD-RTVQrQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGD 508
Cdd:COG1126   142 QQRVAIARALAMEPKVMLFDEPTSALDpELVG-EVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGP 219

                         250
                  ....*....|....*...
gi 1834229548 509 AQSIFAAPQHPYTQQLLE 526
Cdd:COG1126   220 PEEFFENPQHERTRAFLS 237
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
5-260 2.79e-50

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 173.48  E-value: 2.79e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFVVGERCQR-----VVEGVSFDIKRGETLALVGESGSGKSVtahsilrllpypLARHPSGTIE-YSGQN 78
Cdd:COG4167     3 ALLEVRNLSKTFKYRTGLFRrqqfeAVKPVSFTLEAGQTLAIIGENGSGKST------------LAKMLAGIIEpTSGEI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 LLN---LKEKTIRHiRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGI-PEpekrlKAL 154
Cdd:COG4167    71 LINghkLEYGDYKY-RCKHIRMIFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLlPE-----HAN 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 --PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:COG4167   145 fyPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMH 224

                         250       260
                  ....*....|....*....|....*...
gi 1834229548 233 RGCIVEQASCEQLFRAPQHPYTRELLAA 260
Cdd:COG4167   225 QGEVVEYGKTAEVFANPQHEVTKRLIES 252
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
273-506 3.54e-50

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 171.76  E-value: 3.54e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGK 347
Cdd:COG1136     2 SPLLELRNLTKSYGTGEG-------EVTALRGVSLSIEAGEFVAIVGPSGSGKSTL----LNILGgldrpTSGEVLIDGQ 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 348 QLDSLTQQQVRPLRRE-MQVVFQDPFgsLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLDpETRHRYPHEFS 426
Cdd:COG1136    71 DISSLSERELARLRRRhIGFVFQFFN--LLPELTALENVALPLLLAGVSRKERRERAR-ELLERVGLG-DRLDHRPSQLS 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 427 GGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLmVVKQGQVVEQ 506
Cdd:COG1136   147 GGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAARADRVI-RLRDGRIVSD 225
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 299-529 5.85e-50

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 174.99  E-value: 5.85e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDpFG 373
Cdd:PRK11153   18 IHALNNVSLHIPAGEIFGVIGASGAGKSTL----IRCINllerpTSGRVLVDGQDLTALSEKELRKARRQIGMIFQH-FN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SLSPRMcVSQIVGEGLRIhkMGTEAEQEQAIIAALKE-VGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPT 452
Cdd:PRK11153   93 LLSSRT-VFDNVALPLEL--AGTPKAEIKARVTELLElVGLS-DKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEAT 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 453 SALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAF 529
Cdd:PRK11153  169 SALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTREFIQSTL 245
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 3-258 7.65e-50

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 171.32  E-value: 7.65e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   3 QDNLIEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLN 81
Cdd:COG1127     2 SEPMIEVRNLTKSF--GDRV--VLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLR------PdSGEILVDGQDITG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHIRgNRIAMIFQEP--MTSLN-------PLhsIEkqinevlgiHKGLIGKVATKRTLELLEMVGIPEPEKRLk 152
Cdd:COG1127    72 LSEKELYELR-RRIGMLFQGGalFDSLTvfenvafPL--RE---------HTDLSEAEIRELVLEKLELVGLPGAADKM- 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 153 alPHELSGGQRQRVMIAMALANEPELLIADEPTTALD-----VTVQlkileLLKELQARLGMALLLISHDLNLVKRIAHR 227
Cdd:COG1127   139 --PSELSGGMRKRVALARALALDPEILLYDEPTAGLDpitsaVIDE-----LIRELRDELGLTSVVVTHDLDSAFAIADR 211

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1834229548 228 VCVMQRGCIVEQASCEQLfRAPQHPYTRELL 258
Cdd:COG1127   212 VAVLADGKIIAEGTPEEL-LASDDPWVRQFL 241
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 292-507 7.96e-50

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 170.39  E-value: 7.96e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTqqqvrPLRREMQV 366
Cdd:cd03259     6 LSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTL----LRLIAglerpDSGEILIDGRDVTGVP-----PERRNIGM 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDPEtRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03259    77 VFQDY--ALFPHLTVAENIAFGLKLRGVP-KAEIRARVRELLELVGLEGL-LNRYPHELSGGQQQRVALARALAREPSLL 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03259   153 LLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 274-524 2.24e-49

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 170.88  E-value: 2.24e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKvwfpikkgllkKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAI-LRLIGSKGGIRF---EGKQL 349
Cdd:PRK11701    5 PLLSVRGLT-----------KLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALsARLAPDAGEVHYrmrDGQLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 D--SLTQQQVRPL-RREMQVVFQDPFGSLspRMCVSQ--IVGEGLrihkMGTEAEQEQAIIAA----LKEVGLDPETRHR 420
Cdd:PRK11701   74 DlyALSEAERRRLlRTEWGFVHQHPRDGL--RMQVSAggNIGERL----MAVGARHYGDIRATagdwLERVEIDAARIDD 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 421 YPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQ 500
Cdd:PRK11701  148 LPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQ 227

                         250       260
                  ....*....|....*....|....
gi 1834229548 501 GQVVEQGDAQSIFAAPQHPYTQQL 524
Cdd:PRK11701  228 GRVVESGLTDQVLDDPQHPYTQLL 251
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 292-536 3.84e-49

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 173.02  E-value: 3.84e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSltqqQVRPLRREMQV 366
Cdd:COG1118     8 ISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTL----LRIIAgletpDSGRIVLNGRDLFT----NLPPRERRVGF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:COG1118    80 VFQHY--ALFPHMTVAENIAFGLRVRPPS-KAEIRARVEELLELVQLE-GLADRYPSQLSGGQRQRVALARALAVEPEVL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLE 526
Cdd:COG1118   156 LLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLG 235

                         250
                  ....*....|
gi 1834229548 527 AAFLVPATAQ 536
Cdd:COG1118   236 CVNVLRGRVI 245
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 299-503 4.26e-48

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 166.13  E-value: 4.26e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRPLRRE-MQVVFQDPf 372
Cdd:cd03255    17 VQALKGVSLSIEKGEFVAIVGPSGSGKSTL----LNILGgldrpTSGEVRVDGTDISKLSEKELAAFRRRhIGFVFQSF- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 gSLSPRMCVSQIVGEGLRIHKMGTeAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPT 452
Cdd:cd03255    92 -NLLPDLTALENVELPLLLAGVPK-KERRERAEELLERVGLG-DRLNHYPSELSGGQQQRVAIARALANDPKIILADEPT 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 453 SALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKaLSHQLMVVKQGQV 503
Cdd:cd03255   169 GNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 273-505 4.80e-48

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 167.19  E-value: 4.80e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGK 347
Cdd:COG1116     5 APALELRGVSKRFPTGGG-------GVTALDDVSLTVAAGEFVALVGPSGCGKSTL----LRLIAglekpTSGEVLVDGK 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 348 QldsltqqqVRPLRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHKMGTeAEQEQAIIAALKEVGLDpETRHRYPHEFSG 427
Cdd:COG1116    74 P--------VTGPGPDRGVVFQEP--ALLPWLTVLDNVALGLELRGVPK-AERRERARELLELVGLA-GFEDAYPHQLSG 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 428 GQRQRIAIARALVLKPALILLDEPTSALD----RTVQrqvvELLRSLQSKYNLTYLFISHDL--AVvkALSHQLMVVKQ- 500
Cdd:COG1116   142 GMRQRVAIARALANDPEVLLMDEPFGALDaltrERLQ----DELLRLWQETGKTVLFVTHDVdeAV--FLADRVVVLSAr 215


                  ....*.
gi 1834229548 501 -GQVVE 505
Cdd:COG1116   216 pGRIVE 221
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
4-239 9.58e-48

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 165.60  E-value: 9.58e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLpyplaRHP-SGTIEYSGQNLLNL 82
Cdd:COG1136     2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKS-TLLNILGGL-----DRPtSGEVLIDGQDISSL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 KEKTIRHIRGNRIAMIFQEPmtSLNPLHSIEKQINEVLGIhKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQ 162
Cdd:COG1136    76 SERELARLRRRHIGFVFQFF--NLLPELTALENVALPLLL-AGVSRKERRERARELLERVGL---GDRLDHRPSQLSGGQ 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 163 RQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQ 239
Cdd:COG1136   150 QQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAAR-ADRVIRLRDGRIVSD 225
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 7-234 1.47e-47

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 164.59  E-value: 1.47e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:cd03255     1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKS----TLLNIL-GGLDRPTSGEVRVDGTDISKLSEKE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGNRIAMIFQEPmtSLNPLHSIEKQInEVLGIHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRV 166
Cdd:cd03255    76 LAAFRRRHIGFVFQSF--NLLPDLTALENV-ELPLLLAGVPKKERRERAEELLERVGL---GDRLNHYPSELSGGQQQRV 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 167 MIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRG 234
Cdd:cd03255   150 AIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDG 216
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 300-502 1.49e-47

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 164.56  E-value: 1.49e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTqqqVRPLRREMQVVFQDPFgslspr 378
Cdd:cd03225    15 PALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGpTSGEVLVDGKDLTKLS---LKELRRKVGLVFQNPD------ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 mcvSQIVGE--------GLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:cd03225    86 ---DQFFGPtveeevafGLENLGL-PEEEIEERVEEALELVGLE-GLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDE 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:cd03225   161 PTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 273-528 8.50e-47

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 163.85  E-value: 8.50e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKvwfpikkgllkKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAIL-RLIGSKGGIRFEGK---- 347
Cdd:TIGR02323   1 KPLLQVSGLS-----------KSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAgRLAPDHGTATYIMRsgae 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 348 -QLDSLTQQQVRPL-RREMQVVFQDPFGSLspRMCVSQIVGEGLRIHKMGTE--AEQEQAIIAALKEVGLDPETRHRYPH 423
Cdd:TIGR02323  70 lELYQLSEAERRRLmRTEWGFVHQNPRDGL--RMRVSAGANIGERLMAIGARhyGNIRATAQDWLEEVEIDPTRIDDLPR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 424 EFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:TIGR02323 148 AFSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRV 227

                         250       260
                  ....*....|....*....|....*
gi 1834229548 504 VEQGDAQSIFAAPQHPYTQQLLEAA 528
Cdd:TIGR02323 228 VESGLTDQVLDDPQHPYTQLLVSSI 252
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 276-506 1.57e-46

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 161.87  E-value: 1.57e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 276 LTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGkqld 350
Cdd:cd03293     1 LEVRNVSKTYGGGGG-------AVTALEDISLSVEEGEFVALVGPSGCGKSTL----LRIIAglerpTSGEVLVDG---- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 351 sltqQQVRPLRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLDpETRHRYPHEFSGGQR 430
Cdd:cd03293    66 ----EPVTGPGPDRGYVFQQD--ALLPWLTVLDNVALGLELQGVPKAEARERAE-ELLELVGLS-GFENAYPHQLSGGMR 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 431 QRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDL--AVvkALSHQLMVVKQ--GQVVEQ 506
Cdd:cd03293   138 QRVALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIdeAV--FLADRVVVLSArpGRIVAE 215
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 7-256 2.52e-46

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 161.90  E-value: 2.52e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLLNLKEKT 86
Cdd:cd03261     1 IELRGLTKSF--GGR--TVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLR-PD----SGEVLIDGEDISGLSEAE 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgNRIAMIFQEP--MTSLNPLHSIEKQINEvlgiHKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQ 164
Cdd:cd03261    72 LYRLR-RRMGMLFQSGalFDSLTVFENVAFPLRE----HTRLSEEEIREIVLEKLEAVGLRGAEDLY---PAELSGGMKK 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQ 244
Cdd:cd03261   144 RVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEE 223

                         250
                  ....*....|..
gi 1834229548 245 LFRApQHPYTRE 256
Cdd:cd03261   224 LRAS-DDPLVRQ 234
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 275-534 9.71e-46

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 160.98  E-value: 9.71e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVwfpikkGLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLT 353
Cdd:COG1120     1 MLEAENLSV------GYGGRPV-----LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGeVLLDGRDLASLS 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQvrpLRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHK--MGTEAEQEQAIIA-ALKEVGLDpETRHRYPHEFSGGQR 430
Cdd:COG1120    70 RRE---LARRIAYVPQEP--PAPFGLTVRELVALGRYPHLglFGRPSAEDREAVEeALERTGLE-HLADRPVDELSGGER 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 431 QRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQ 510
Cdd:COG1120   144 QRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPE 223

                         250       260
                  ....*....|....*....|....
gi 1834229548 511 SIFaapqhpyTQQLLEAAFLVPAT 534
Cdd:COG1120   224 EVL-------TPELLEEVYGVEAR 240
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
299-505 3.65e-45

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 158.29  E-value: 3.65e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDpFG 373
Cdd:COG2884    15 REALSDVSLEIEKGEFVFLTGPSGAGKSTL----LKLLYgeerpTSGQVLVNGQDLSRLKRREIPYLRRRIGVVFQD-FR 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 sLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:COG2884    90 -LLPDRTVYENVALPLRVTGK-SRKEIRRRVREVLDLVGLS-DKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTG 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 454 ALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVE 505
Cdd:COG2884   167 NLDPETSWEIMELLEEI-NRRGTTVLIATHDLELVDRMPKRVLELEDGRLVR 217
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
299-528 9.69e-45

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 160.84  E-value: 9.69e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGI-----RFEGKQLDSLTQQQVRPL-RREMQVVFQDPF 372
Cdd:COG4170    20 VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWHVtadrfRWNGIDLLKLSPRERRKIiGREIAMIFQEPS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 GSLSPrmcvSQIVGEGL---------RIHKMGTEAEQEQAIIAALKEVGL-DPETRHR-YPHEFSGGQRQRIAIARALVL 441
Cdd:COG4170   100 SCLDP----SAKIGDQLieaipswtfKGKWWQRFKWRKKRAIELLHRVGIkDHKDIMNsYPHELTEGECQKVMIAMAIAN 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 442 KPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYT 521
Cdd:COG4170   176 QPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSPHHPYT 255


                  ....*..
gi 1834229548 522 QQLLEAA 528
Cdd:COG4170   256 KALLRSM 262
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
23-272 1.27e-44

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 158.31  E-value: 1.27e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAhsilRLLpYPLARHPSGTIEYSGQNLLNLKEKTIRHIRGNrIAMIFQEP 102
Cdd:PRK10419   25 QTVLNNVSLSLKSGETVALLGRSGCGKSTLA----RLL-VGLESPSQGNVSWRGEPLAKLNRAQRKAFRRD-IQMVFQDS 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:PRK10419   99 ISAVNPRKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLDD--SVLDKRPPQLSGGQLQRVCLARALAVEPKLLILD 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRApQHPYTRELLAAEP 262
Cdd:PRK10419  177 EAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVGDKLTF-SSPAGRVLQNAVL 255

                         250
                  ....*....|
gi 1834229548 263 SGTPATNVVG 272
Cdd:PRK10419  256 PAFPVRRRTT 265
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 274-504 1.70e-44

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 157.53  E-value: 1.70e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQ 348
Cdd:COG3638     1 PMLELRNLSKRYP----------GGTPALDDVSLEIERGEFVALIGPSGAGKSTL----LRCLNglvepTSGEILVDGQD 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDSLTQQQVRPLRREMQVVFQDPfgSLSPRMCVSQIVGEGlRIHKMGT---------EAEQEQAIiAALKEVGLDPETRH 419
Cdd:COG3638    67 VTALRGRALRRLRRRIGMIFQQF--NLVPRLSVLTNVLAG-RLGRTSTwrsllglfpPEDRERAL-EALERVGLADKAYQ 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 420 RyPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVK 499
Cdd:COG3638   143 R-ADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLR 221


                  ....*
gi 1834229548 500 QGQVV 504
Cdd:COG3638   222 DGRVV 226
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 288-520 2.08e-44

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 157.81  E-value: 2.08e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 288 KKGLLKKTvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRPLRRE-MQ 365
Cdd:cd03294    27 KEEILKKT-GQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEpTSGKVLIDGQDIAAMSRKELRELRRKkIS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 366 VVFQDpFGsLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDPEtRHRYPHEFSGGQRQRIAIARALVLKPAL 445
Cdd:cd03294   106 MVFQS-FA-LLPHRTVLENVAFGLEVQGVP-RAEREERAAEALELVGLEGW-EHKYPDELSGGMQQRVGLARALAVDPDI 181

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPY 520
Cdd:cd03294   182 LLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDY 256
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 292-517 8.02e-44

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 155.09  E-value: 8.02e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLdsltqQQVRPLRREMQV 366
Cdd:cd03300     6 VSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTL----LRLIAgfetpTSGEILLDGKDI-----TNLPPHKRPVNT 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03300    77 VFQNY--ALFPHLTVFENIAFGLRLKKLP-KAEIKERVAEALDLVQLE-GYANRKPSQLSGGQQQRVAIARALVNEPKVL 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:cd03300   153 LLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPA 223
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 7-245 1.33e-42

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 151.56  E-value: 1.33e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:cd03260     1 IELRDLNVYY--GDKH--ALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGAPDEGEVLLDGKDIYDLDVDV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgnRIAMIFQEPmtslNPLH-SIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRlKALPHELSGGQRQR 165
Cdd:cd03260    77 LELRR--RVGMVFQKP----NPFPgSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKD-RLHALGLSGGQQQR 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTvqLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:cd03260   150 LCLARALANEPEVLLLDEPTSALDPI--STAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 276-512 1.63e-42

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 151.56  E-value: 1.63e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 276 LTVEDLKVWFpikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG------SKGGIRFEGKQL 349
Cdd:cd03260     1 IELRDLNVYY-----------GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgapDEGEVLLDGKDI 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLtQQQVRPLRREMQVVFQ--DPFgslspRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPET-RHRYPHEFS 426
Cdd:cd03260    70 YDL-DVDVLELRRRVGMVFQkpNPF-----PGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVkDRLHALGLS 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 427 GGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYnlTYLFISHDLAVVKALSHQLMVVKQGQVVEQ 506
Cdd:cd03260   144 GGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKEY--TIVIVTHNMQQAARVADRTAFLLNGRLVEF 221


                  ....*.
gi 1834229548 507 GDAQSI 512
Cdd:cd03260   222 GPTEQI 227
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 300-536 1.92e-42

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 152.99  E-value: 1.92e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDP--- 371
Cdd:TIGR04521  19 KALDDVSLTIEDGEFVAIIGHTGSGKSTLiqhlnGL----LKPTSGTVTIDGRDITAKKKKKLKDLRKKVGLVFQFPehq 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 -----------FGslsPRMcvsqivgeglrihkMG-TEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARAL 439
Cdd:TIGR04521  95 lfeetvykdiaFG---PKN--------------LGlSEEEAEERVKEALELVGLDEEYLERSPFELSGGQMRRVAIAGVL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 440 VLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPqhp 519
Cdd:TIGR04521 158 AMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV--- 234

                         250
                  ....*....|....*...
gi 1834229548 520 ytqQLLEAAFL-VPATAQ 536
Cdd:TIGR04521 235 ---DELEKIGLdVPEITE 249
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 300-525 4.42e-42

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 150.91  E-value: 4.42e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDPfgSLSPR 378
Cdd:cd03295    15 KAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEpTSGEIFIDGE---DIREQDPVELRRKIGYVIQQI--GLFPH 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLDPET-RHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:cd03295    90 MTVEENIALVPKLLKWPKEKIRERAD-ELLALVGLDPAEfADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDP 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 458 TVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLL 525
Cdd:cd03295   169 ITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFV 236
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 7-250 5.61e-42

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 150.18  E-value: 5.61e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLlnlKEKT 86
Cdd:COG1122     1 IELENLSFSYP-GGT--PALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLL-----KPTSGEVLVDGKDI---TKKN 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgNRIAMIFQEPmtslnplhsiEKQI------NEV-LG-IHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHEL 158
Cdd:COG1122    70 LRELR-RKVGLVFQNP----------DDQLfaptveEDVaFGpENLGLPREEIRERVEEALELVGL---EHLADRPPHEL 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDvtvqlkilellKELQARL----------GMALLLISHDLNLVKRIAHRV 228
Cdd:COG1122   136 SGGQKQRVAIAGVLAMEPEVLVLDEPTAGLD-----------PRGRRELlellkrlnkeGKTVIIVTHDLDLVAELADRV 204

                         250       260
                  ....*....|....*....|..
gi 1834229548 229 CVMQRGCIVEQASCEQLFRAPQ 250
Cdd:COG1122   205 IVLDDGRIVADGTPREVFSDYE 226
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 7-260 7.40e-42

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 153.03  E-value: 7.40e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:PRK11153    2 IELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKS----TLIRCINL-LERPTSGRVLVDGQDLTALSEKE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgNRIAMIFQEpmtsLNPLHSIEKQIN-----EVLGIHKGLIgkvaTKRTLELLEMVGIPEpeKRlKALPHELSGG 161
Cdd:PRK11153   77 LRKAR-RQIGMIFQH----FNLLSSRTVFDNvalplELAGTPKAEI----KARVTELLELVGLSD--KA-DRYPAQLSGG 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQAS 241
Cdd:PRK11153  145 QKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGT 224

                         250
                  ....*....|....*....
gi 1834229548 242 CEQLFRAPQHPYTRELLAA 260
Cdd:PRK11153  225 VSEVFSHPKHPLTREFIQS 243
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4-504 7.92e-42

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 156.72  E-value: 7.92e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEF--VvgercqRVVEGVSFDIKRGETLALVGESGSGKSvTAHSILrllpyplA---RHPSGTIEYSGQN 78
Cdd:COG1129     2 EPLLEMRGISKSFggV------KALDGVSLELRPGEVHALLGENGAGKS-TLMKIL-------SgvyQPDSGEILLDGEP 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 LlnlKEKTIRHIRGNRIAMIFQEPmtSLNPLHSIEKQIneVLG---IHKGLIGKVAT-KRTLELLEMVGIPE-PEKRLKa 153
Cdd:COG1129    68 V---RFRSPRDAQAAGIAIIHQEL--NLVPNLSVAENI--FLGrepRRGGLIDWRAMrRRARELLARLGLDIdPDTPVG- 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 154 lphELSGGQRQRVMIAMALANEPELLIADEPTTALDVT-VQlkilellkelqaRL----------GMALLLISHDLNLVK 222
Cdd:COG1129   140 ---DLSVAQQQLVEIARALSRDARVLILDEPTASLTEReVE------------RLfriirrlkaqGVAIIYISHRLDEVF 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 223 RIAHRVCVMQRGCIVEQASCEQLfrapqhpyT----------RELLAAEPSGTPATnvvGPPMLTVEDLKVWfpikkgll 292
Cdd:COG1129   205 EIADRVTVLRDGRLVGTGPVAEL--------TedelvrlmvgRELEDLFPKRAAAP---GEVVLEVEGLSVG-------- 265

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 293 kktvdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDsltqqqvrpLRremqvvfqdp 371
Cdd:COG1129   266 -------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGeIRLDGKPVR---------IR---------- 319

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 fgslSPRMCVSQ-IV-------GEGL----------------RIHKMG--TEAEQEQAIIAALKEVGLDPETRHRYPHEF 425
Cdd:COG1129   320 ----SPRDAIRAgIAyvpedrkGEGLvldlsirenitlasldRLSRGGllDRRRERALAEEYIKRLRIKTPSPEQPVGNL 395

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 426 SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:COG1129   396 SGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDRILVMREGRIV 473
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 275-530 1.17e-41

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 149.62  E-value: 1.17e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKvwfpikkgllkKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-----GSKGGIRFEGKQL 349
Cdd:COG4555     1 MIEVENLS-----------KKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTL----LRMLagllkPDSGSILIDGEDV 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 dsltQQQVRPLRREMQVVFQDPFgsLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQ 429
Cdd:COG4555    66 ----RKEPREARRQIGVLPDERG--LYDRLTVRENIRYFAELYGL-FDEELKKRIEELIELLGLE-EFLDRRVGELSTGM 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:COG4555   138 KKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSL 216

                         250       260
                  ....*....|....*....|.
gi 1834229548 510 QSIFAApqhpYTQQLLEAAFL 530
Cdd:COG4555   217 DELREE----IGEENLEDAFV 233
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 299-502 1.64e-41

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 146.95  E-value: 1.64e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQqVRPLRREMQVVFQDPfg 373
Cdd:cd03229    13 KTVLNDVSLNIEAGEIVALLGPSGSGKSTL----LRCIAgleepDSGSILIDGEDLTDLEDE-LPPLRRRIGMVFQDF-- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SLSPRMCVSQIVGEGLrihkmgteaeqeqaiiaalkevgldpetrhryphefSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:cd03229    86 ALFPHLTVLENIALGL------------------------------------SGGQQQRVALARALAMDPDVLLLDEPTS 129

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1834229548 454 ALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:cd03229   130 ALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
292-530 2.51e-41

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 148.67  E-value: 2.51e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-G----SKGGIRFEGKQLDSLTQQqvrpLRREMQV 366
Cdd:COG1131     6 LTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTT----IRMLlGllrpTSGEVRVLGEDVARDPAE----VRRRIGY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:COG1131    78 VPQEP--ALYPDLTVRENLRFFARLYGL-PRKEARERIDELLELFGLT-DAADRKVGTLSGGMKQRLGLALALLHDPELL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIfaapqhpyTQQLLE 526
Cdd:COG1131   154 ILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL--------KARLLE 224


                  ....
gi 1834229548 527 AAFL 530
Cdd:COG1131   225 DVFL 228
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
303-503 4.67e-41

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 146.88  E-value: 4.67e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDP--FGslsprm 379
Cdd:COG4619    17 SPVSLTLEAGECVAITGPSGSGKSTLLRALADLDpPTSGEIYLDGKPLSAMPPPE---WRRQVAYVPQEPalWG------ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 cvsQIVGEGL-RIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:COG4619    88 ---GTVRDNLpFPFQLRERKFDRERALELLERLGLPPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPE 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 459 VQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:COG4619   165 NTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 299-514 5.34e-41

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 148.73  E-value: 5.34e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGkqLDSLTQQQVRPLRREMQVVFQDP-- 371
Cdd:TIGR04520  15 KPALKNVSLSIEKGEFVAIIGHNGSGKSTLakllnGL----LLPTSGKVTVDG--LDTLDEENLWEIRKKVGMVFQNPdn 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 -FgslsprmcVSQIVGE----GLriHKMGTEAEQEQAIIA-ALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPAL 445
Cdd:TIGR04520  89 qF--------VGATVEDdvafGL--ENLGVPREEMRKRVDeALKLVGME-DFRDREPHLLSGGQKQRVAIAGVLAMRPDI 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:TIGR04520 158 IILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIFS 225
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 26-256 6.04e-41

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 148.56  E-value: 6.04e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQE--P 102
Cdd:cd03294    40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIE------PtSGKVLIDGQDIAAMSRKELRELRRKKISMVFQSfaL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNPLHSIEKQInEVLGIHKgligKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03294   114 LPHRTVLENVAFGL-EVQGVPR----AEREERAAEALELVGL---EGWEHKYPDELSGGMQQRVGLARALAVDPDILLMD 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRE 256
Cdd:cd03294   186 EAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVRE 259
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 292-518 1.14e-40

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 150.22  E-value: 1.14e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-G----SKGGIRFEGKQLDSLtqqqvRPLRREMQV 366
Cdd:COG3839     9 VSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTL----LRMIaGledpTSGEILIGGRDVTDL-----PPKDRNIAM 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:COG3839    80 VFQSY--ALYPHMTVYENIAFPLKLRKV-PKAEIDRRVREAAELLGLED-LLDRKPKQLSGGQRQRVALGRALVREPKVF 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQH 518
Cdd:COG3839   156 LLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPAN 227
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
25-238 2.07e-40

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 145.58  E-value: 2.07e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYpLARHP-SGTIEYSGQNLLNLKEKTIRHIRgNRIAMIFQE-- 101
Cdd:COG2884    17 ALSDVSLEIEKGEFVFLTGPSGAGKS----TLLKLL-Y-GEERPtSGQVLVNGQDLSRLKRREIPYLR-RRIGVVFQDfr 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 -------------PMtslnplhsiekqinEVLGIHKGLIGkvatKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMI 168
Cdd:COG2884    90 llpdrtvyenvalPL--------------RVTGKSRKEIR----RRVREVLDLVGL---SDKAKALPHELSGGEQQRVAI 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 169 AMALANEPELLIADEPTTALDvtvqlkilellkELQA-----------RLGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:COG2884   149 ARALVNRPELLLADEPTGNLD------------PETSweimelleeinRRGTTVLIATHDLELVDRMPKRVLELEDGRLV 216


                  .
gi 1834229548 238 E 238
Cdd:COG2884   217 R 217
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
305-525 2.38e-40

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 145.67  E-value: 2.38e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLtqqqvRPLRREMQVVFQDpfGSLSPRM 379
Cdd:COG3840    18 FDLTIAAGERVAILGPSGAGKSTL----LNLIAgflppDSGRILWNGQDLTAL-----PPAERPVSMLFQE--NNLFPHL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 CVSQIVGEGLRiHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTV 459
Cdd:COG3840    87 TVAQNIGLGLR-PGLKLTAEQRAQVEQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPAL 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 460 QRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLL 525
Cdd:COG3840   165 RQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYL 230
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 301-520 3.32e-40

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 154.99  E-value: 3.32e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPF---GSLS 376
Cdd:COG2274   490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYePTSGRILIDGIDLRQIDPAS---LRRQIGVVLQDVFlfsGTIR 566

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prmcvsqivgEGLRIHKmgTEAEQEQaIIAALKEVGLDPETRHRyPH-----------EFSGGQRQRIAIARALVLKPAL 445
Cdd:COG2274   567 ----------ENITLGD--PDATDEE-IIEAARLAGLHDFIEAL-PMgydtvvgeggsNLSGGQRQRLAIARALLRNPRI 632

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLqsKYNLTYLFISHDLAVVKaLSHQLMVVKQGQVVEQGDAQSIFAAPQHPY 520
Cdd:COG2274   633 LILDEATSALDAETEAIILENLRRL--LKGRTVIIIAHRLSTIR-LADRIIVLDKGRIVEDGTHEELLARKGLYA 704
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 302-517 5.37e-40

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 144.79  E-value: 5.37e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTqqqvrPLRREMQVVFQDPfgSLSPRMC 380
Cdd:cd03299    15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGkILLNGKDITNLP-----PEKRDISYVPQNY--ALFPHMT 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRiHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQ 460
Cdd:cd03299    88 VYKNIAYGLK-KRKVDKKEIERKVLEIAEMLGID-HLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTK 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 461 RQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:cd03299   166 EKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPK 222
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 303-505 6.01e-40

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 144.42  E-value: 6.01e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRPLR-REMQVVFQdpFGSLS 376
Cdd:TIGR02211  22 KGVSLSIGKGEIVAIVGSSGSGKSTL----LHLLGgldnpTSGEVLFNGQSLSKLSSNERAKLRnKKLGFIYQ--FHHLL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 PRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:TIGR02211  96 PDFTALENVAMPLLIGKK-SVKEAKERAYEMLEKVGLEHRINHR-PSELSGGERQRVAIARALVNQPSLVLADEPTGNLD 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1834229548 457 RTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALShQLMVVKQGQVVE 505
Cdd:TIGR02211 174 NNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKLD-RVLEMKDGQLFN 221
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 302-453 1.42e-39

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 140.86  E-value: 1.42e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLdslTQQQVRPLRREMQVVFQDPFgsLSPRMC 380
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLsPTEGTILLDGQDL---TDDERKSLRKEIGYVFQDPQ--LFPRLT 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 381 VSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGL--DPETR-HRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:pfam00005  76 VRENLRLGLLLKGLSKREKDARAE-EALEKLGLgdLADRPvGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 239-510 1.67e-39

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 151.45  E-value: 1.67e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 239 QASCEQLFRAPQHPytrelLAAEPSGTPATNVVGPPMLTVEDLKVWFPikkgllkktvDYVKAVDGINFSLPQGQTLGIV 318
Cdd:COG4988   305 IAAAEKIFALLDAP-----EPAAPAGTAPLPAAGPPSIELEDVSFSYP----------GGRPALDGLSLTIPPGERVALV 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 319 GESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPF---GSLSprmcvsqivgEGLRihkM 394
Cdd:COG4988   370 GPSGAGKSTLLNLLLGFLPpYSGSILINGVDLSDLDPAS---WRRQIAWVPQNPYlfaGTIR----------ENLR---L 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 395 GTEAEQEQAIIAALKEVGLDPETRhRYPHEF-----------SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQV 463
Cdd:COG4988   434 GRPDASDEELEAALEAAGLDEFVA-ALPDGLdtplgeggrglSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEI 512

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 464 VELLRSLqSKyNLTYLFISHDLAVVKALSHQLmVVKQGQVVEQGDAQ 510
Cdd:COG4988   513 LQALRRL-AK-GRTVILITHRLALLAQADRIL-VLDDGRIVEQGTHE 556
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 28-504 1.70e-39

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 150.18  E-value: 1.70e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSvTAHSILrllpYPLARHPSGTIEYSGqnllnlKEKTI---RHIRGNRIAMIFQEPMt 104
Cdd:COG3845    23 DVSLTVRPGEIHALLGENGAGKS-TLMKIL----YGLYQPDSGEILIDG------KPVRIrspRDAIALGIGMVHQHFM- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 sLNPLHS-IEkqiNEVLGIHKGLIG----KVATKRTLELLEMVGIP-EPEkrlkALPHELSGGQRQRVMIAMALANEPEL 178
Cdd:COG3845    91 -LVPNLTvAE---NIVLGLEPTKGGrldrKAARARIRELSERYGLDvDPD----AKVEDLSVGEQQRVEILKALYRGARI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 179 LIADEPTTALdvTVQLKILELLKELQ-ARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLfrapqhpyTREL 257
Cdd:COG3845   163 LILDEPTAVL--TPQEADELFEILRRlAAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAET--------SEEE 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 258 LAA-------EPSGTPATNVVGPPMLTVEDLKVwfpikkgllkKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGL 330
Cdd:COG3845   233 LAElmvgrevLLRVEKAPAEPGEVVLEVENLSV----------RDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAE 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 331 AI--LRLIgSKGGIRFEGKQLDSLTQQQvrplRREMQVVF--QDPFGS-LSPRMCVSQ--IVGEG----------LRIHK 393
Cdd:COG3845   303 ALagLRPP-ASGSIRLDGEDITGLSPRE----RRRLGVAYipEDRLGRgLVPDMSVAEnlILGRYrrppfsrggfLDRKA 377

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 394 MGTEAEQeqaIIAALKEVGLDPETRHRyphEFSGGQRQRIAIARALVLKPALILLDEPTSALD----RTVQRQVVELLRS 469
Cdd:COG3845   378 IRAFAEE---LIEEFDVRTPGPDTPAR---SLSGGNQQKVILARELSRDPKLLIAAQPTRGLDvgaiEFIHQRLLELRDA 451

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 1834229548 470 lqskyNLTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:COG3845   452 -----GAAVLLISEDLDEILALSDRIAVMYEGRIV 481
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 6-245 4.30e-39

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 142.89  E-value: 4.30e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLKE 84
Cdd:COG3638     2 MLELRNLSKRYPGG---TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVE------PtSGEILVDGQDVTALRG 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KTIRHIRGnRIAMIFQEPmtslnPLhsIEKQ--INEVL-------GIHKGLIGKVATK---RTLELLEMVGIPEpekrlK 152
Cdd:COG3638    73 RALRRLRR-RIGMIFQQF-----NL--VPRLsvLTNVLagrlgrtSTWRSLLGLFPPEdreRALEALERVGLAD-----K 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 153 AL--PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCV 230
Cdd:COG3638   140 AYqrADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIG 219

                         250
                  ....*....|....*
gi 1834229548 231 MQRGCIVEQASCEQL 245
Cdd:COG3638   220 LRDGRVVFDGPPAEL 234
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 289-512 4.39e-39

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 142.71  E-value: 4.39e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 289 KGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLDSLTQQQVRPLRREMQVV 367
Cdd:cd03256     4 ENLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVePTSGSVLIDGTDINKLKGKALRQLRRQIGMI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 368 FQDPfgSLSPRMCVSQIVGEG-------LR-IHKMGTEAEQEQAIiAALKEVGLDPETRHRyPHEFSGGQRQRIAIARAL 439
Cdd:cd03256    84 FQQF--NLIERLSVLENVLSGrlgrrstWRsLFGLFPKEEKQRAL-AALERVGLLDKAYQR-ADQLSGGQQQRVAIARAL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 440 VLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:cd03256   160 MQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
7-245 8.11e-39

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 141.74  E-value: 8.11e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLKEK 85
Cdd:COG1131     1 IEVRGLTKRY--GDK--TALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLR------PtSGEVRVLGEDVARDPAE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRhirgnRIAMIFQEPmtSLNPLHSIEKQINEVLGIHkGLIGKVATKRTLELLEMVGIPEpekRLKALPHELSGGQRQR 165
Cdd:COG1131    71 VRR-----RIGYVPQEP--ALYPDLTVRENLRFFARLY-GLPRKEARERIDELLELFGLTD---AADRKVGTLSGGMKQR 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVtVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:COG1131   140 LGLALALLHDPELLILDEPTSGLDP-EARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 7-240 1.12e-38

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 140.73  E-value: 1.12e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKekt 86
Cdd:cd03259     1 LELKGLSKTY--GS--VRALDDLSLTVEPGEFLALLGPSGCGKT----TLLRLIA-GLERPDSGEILIDGRDVTGVP--- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 irhIRGNRIAMIFQEPmtSLNPLHSIEKQIneVLGIHKGLIGK-VATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQR 165
Cdd:cd03259    69 ---PERRNIGMVFQDY--ALFPHLTVAENI--AFGLKLRGVPKaEIRARVRELLELVGLEGLLNRY---PHELSGGQQQR 138

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQA 240
Cdd:cd03259   139 VALARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 23-261 1.18e-38

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 141.67  E-value: 1.18e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLKEKTIRHirgnRIAMIFQEp 102
Cdd:cd03295    14 KKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLI-----EPTSGEIFIDGEDIREQDPVELRR----KIGYVIQQ- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 mTSLNPLHSIEKQINEVLGIHKGLIGKVAtKRTLELLEMVGIPePEKRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03295    84 -IGLFPHMTVEENIALVPKLLKWPKEKIR-ERADELLALVGLD-PAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELLAAE 261
Cdd:cd03295   161 EPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVGAD 239
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 292-503 2.05e-38

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 139.97  E-value: 2.05e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSlTQQQVRPLRREMQV 366
Cdd:cd03262     6 LHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTL----LRCINlleepDSGTIIIDGLKLTD-DKKNINELRQKVGM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDpFgSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03262    81 VFQQ-F-NLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLA-DKADAYPAQLSGGQQQRVAIARALAMNPKVM 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:cd03262   158 LFDEPTSALDPELVGEVLDVMKDL-AEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 300-525 2.16e-38

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 140.55  E-value: 2.16e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQvrplrREMQVVFQDPfgS 374
Cdd:cd03296    16 VALDDVSLDIPSGELVALLGPSGSGKTTL----LRLIAglerpDSGTILFGGEDATDVPVQE-----RNVGFVFQHY--A 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 LSPRMCVSQIVGEGLRIHKMGT---EAEQEQAIIAALKEVGLDPETRhRYPHEFSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:cd03296    85 LFRHMTVFDNVAFGLRVKPRSErppEAEIRAKVHELLKLVQLDWLAD-RYPAQLSGGQRQRVALARALAVEPKVLLLDEP 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 452 TSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLL 525
Cdd:cd03296   164 FGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFL 237
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 273-529 2.79e-38

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 140.61  E-value: 2.79e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLkvwfpikkgllkkTVDY--VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKql 349
Cdd:COG1121     4 MPAIELENL-------------TVSYggRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPpTSGTVRLFGK-- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 dSLTQQQVR----PLRREMQVVFqdPfgslsprMCVSQIVGEGlRIHKMG----TEAEQEQAIIAALKEVGLDpETRHRY 421
Cdd:COG1121    69 -PPRRARRRigyvPQRAEVDWDF--P-------ITVRDVVLMG-RYGRRGlfrrPSRADREAVDEALERVGLE-DLADRP 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 422 PHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQsKYNLTYLFISHDLAVVKALSHQLMVVKQG 501
Cdd:COG1121   137 IGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELR-REGKTILVVTHDLGAVREYFDRVLLLNRG 215

                         250       260
                  ....*....|....*....|....*...
gi 1834229548 502 qVVEQGDAQSIFaapqhpyTQQLLEAAF 529
Cdd:COG1121   216 -LVAHGPPEEVL-------TPENLSRAY 235
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 275-512 3.60e-38

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 140.13  E-value: 3.60e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKgllkktvdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLT 353
Cdd:TIGR02315   1 MLEVENLSKVYPNGK----------QALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEpSSGSILLEGTDITKLR 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQVRPLRREMQVVFQDpfGSLSPRMCVSQIVGEGlRIHKMGT---------EAEQEQAIiAALKEVGLDpETRHRYPHE 424
Cdd:TIGR02315  71 GKKLRKLRRRIGMIFQH--YNLIERLTVLENVLHG-RLGYKPTwrsllgrfsEEDKERAL-SALERVGLA-DKAYQRADQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 425 FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:TIGR02315 146 LSGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIV 225


                  ....*...
gi 1834229548 505 EQGDAQSI 512
Cdd:TIGR02315 226 FDGAPSEL 233
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
305-517 4.46e-38

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 140.15  E-value: 4.46e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLgLAILRL--IGSKGGIRFEGKQLD---SLTQQQVRPLRREMQVVFQDPfgSLSPRM 379
Cdd:COG4161    21 INLECPSGETLVLLGPSGAGKSSL-LRVLNLleTPDSGQLNIAGHQFDfsqKPSEKAIRLLRQKVGMVFQQY--NLWPHL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 CVSQIVGEG-LRIHKMGTEAEQEQAIiAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:COG4161    98 TVMENLIEApCKVLGLSKEQAREKAM-KLLARLRLT-DKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 459 VQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAqSIFAAPQ 517
Cdd:COG4161   176 ITAQVVEIIREL-SQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDA-SHFTQPQ 232
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 300-526 7.10e-38

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 143.07  E-value: 7.10e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRPLRR-EMQVVFQDpFGsLSP 377
Cdd:TIGR01186   7 KGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEpTAGQIFIDGENIMKQSPVELREVRRkKIGMVFQQ-FA-LFP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLdPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:TIGR01186  85 HMTILQNTSLGPELLGWPEQERKEKAL-ELLKLVGL-EEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDP 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 458 TVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLE 526
Cdd:TIGR01186 163 LIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIG 231
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-234 9.52e-38

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 139.45  E-value: 9.52e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQ-DNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNL 79
Cdd:COG1116     1 MSAaAPALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKS----TLLRLI-AGLEKPTSGEVLVDGKPV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  80 lnlkektirHIRGNRIAMIFQEPmtSLNPLHSIEKqiNEVLGI-HKGLIGKVATKRTLELLEMVGIpepEKRLKALPHEL 158
Cdd:COG1116    76 ---------TGPGPDRGVVFQEP--ALLPWLTVLD--NVALGLeLRGVPKAERRERARELLELVGL---AGFEDAYPHQL 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDV----TVQlkilELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:COG1116   140 SGGMRQRVAIARALANDPEVLLMDEPFGALDAltreRLQ----DELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSAR 215
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 6-260 9.59e-38

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 139.41  E-value: 9.59e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLLNLKEK 85
Cdd:COG1120     1 MLEAENLSVGY--GGR--PVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLK-PS----SGEVLLDGRDLASLSRR 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TirhiRGNRIAMIFQEPMTSLnPLhSIEkqinEVLGI----HKGLIGKVATK---RTLELLEMVGIPEpeKRLKALpHEL 158
Cdd:COG1120    72 E----LARRIAYVPQEPPAPF-GL-TVR----ELVALgrypHLGLFGRPSAEdreAVEEALERTGLEH--LADRPV-DEL 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVE 238
Cdd:COG1120   139 SGGERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVA 218

                         250       260
                  ....*....|....*....|..
gi 1834229548 239 QASCEQLFrapqhpyTRELLAA 260
Cdd:COG1120   219 QGPPEEVL-------TPELLEE 233
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 7-236 1.29e-37

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 137.66  E-value: 1.29e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNLlNLKEKT 86
Cdd:cd03262     1 IEIKNLHKSF--GD--FHVLKGIDLTVKKGEVVVIIGPSGSGKS----TLLRCINL-LEEPDSGTIIIDGLKL-TDDKKN 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgNRIAMIFQ-----EPMTSLNPLhsIEKQInEVLGIHKgligKVATKRTLELLEMVGIPEpekRLKALPHELSGG 161
Cdd:cd03262    71 INELR-QKVGMVFQqfnlfPHLTVLENI--TLAPI-KVKGMSK----AEAEERALELLEKVGLAD---KADAYPAQLSGG 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALD---------VTVQLkilellkelqARLGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:cd03262   140 QQQRVAIARALAMNPKVMLFDEPTSALDpelvgevldVMKDL----------AEEGMTMVVVTHEMGFAREVADRVIFMD 209


                  ....
gi 1834229548 233 RGCI 236
Cdd:cd03262   210 DGRI 213
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
287-536 1.42e-37

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 141.78  E-value: 1.42e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 287 IKKGLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTlglaILRLIG-----SKGGIRFEGKQL-DSLTQQqvrpl 360
Cdd:PRK11432   12 ITKRFGSNTV-----IDNLNLTIKQGTMVTLLGPSGCGKTT----VLRLVAglekpTEGQIFIDGEDVtHRSIQQ----- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 361 rREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHKMGTEaEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALV 440
Cdd:PRK11432   78 -RDICMVFQSY--ALFPHMSLGENVGYGLKMLGVPKE-ERKQRVKEALELVDLA-GFEDRYVDQISGGQQQRVALARALI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 441 LKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPY 520
Cdd:PRK11432  153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRF 232

                         250
                  ....*....|....*.
gi 1834229548 521 TQQLLEAAFLVPATAQ 536
Cdd:PRK11432  233 MASFMGDANIFPATLS 248
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 304-526 2.71e-37

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 137.96  E-value: 2.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLD---SLTQQQ--VRPLRREMQVVFQDpFg 373
Cdd:PRK11264   21 GIDLEVKPGEVVAIIGPSGSGKTTL----LRCINlleqpEAGTIRVGDITIDtarSLSQQKglIRQLRQHVGFVFQN-F- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPEtRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:PRK11264   95 NLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGK-ETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTS 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 454 ALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLE 526
Cdd:PRK11264  174 ALDPELVGEVLNTIRQL-AQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRTRQFLE 245
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 299-502 4.33e-37

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 134.82  E-value: 4.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPF---GS 374
Cdd:cd03228    15 KPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYdPTSGEILIDGVDLRDLDLES---LRKNIAYVPQDPFlfsGT 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 LsprmcvsqivgeglrihkmgteaeqeqaiiaalKEVGLdpetrhryphefSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:cd03228    92 I---------------------------------RENIL------------SGGQRQRIAIARALLRDPPILILDEATSA 126

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1834229548 455 LDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKaLSHQLMVVKQGQ 502
Cdd:cd03228   127 LDPETEALILEALRALAK--GKTVIVIAHRLSTIR-DADRIIVLDDGR 171
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 7-231 4.42e-37

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 136.45  E-value: 4.42e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLlnlkekt 86
Cdd:cd03293     1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKS----TLLRIIA-GLERPTSGEVLVDGEPV------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 irHIRGNRIAMIFQEPmtSLNPLHSIEKqiNEVLGI-HKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQR 165
Cdd:cd03293    69 --TGPGPDRGYVFQQD--ALLPWLTVLD--NVALGLeLQGVPKAEARERAEELLELVGL---SGFENAYPHQLSGGMRQR 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVM 231
Cdd:cd03293   140 VALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 8-234 4.46e-37

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 136.06  E-value: 4.46e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYSGQNLlnl 82
Cdd:cd03225     1 ELKN--LSFSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKS----TLLRLLngllgPT------SGEVLVDGKDL--- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 KEKTIRHIRGnRIAMIFQEPMTSL-NPlhSIEKQINEVLGiHKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGG 161
Cdd:cd03225    66 TKLSLKELRR-KVGLVFQNPDDQFfGP--TVEEEVAFGLE-NLGLPEEEIEERVEEALELVGLEGLRDRS---PFTLSGG 138

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd03225   139 QKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDG 210
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 301-525 6.41e-37

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 136.85  E-value: 6.41e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLdsltqQQVRPLRREMQVVFQDPfgSL 375
Cdd:TIGR00968  15 ALDDVNLEVPTGSLVALLGPSGSGKSTL----LRIIAgleqpDSGRIRLNGQDA-----TRVHARDRKIGFVFQHY--AL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:TIGR00968  84 FKHLTVRDNIAFGLEIRKH-PKAKIKARVEELLELVQLE-GLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPFGAL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLL 525
Cdd:TIGR00968 162 DAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFL 231
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 26-186 8.32e-37

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 133.54  E-value: 8.32e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLnlkeKTIRHIRGNRIAMIFQEPmtS 105
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPT-----EGTILLDGQDLT----DDERKSLRKEIGYVFQDP--Q 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LNPLHSIEKQINEVLGIhKGLIGKVATKRTLELLEMVGIPEPEKR-LKALPHELSGGQRQRVMIAMALANEPELLIADEP 184
Cdd:pfam00005  70 LFPRLTVRENLRLGLLL-KGLSKREKDARAEEALEKLGLGDLADRpVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148


                  ..
gi 1834229548 185 TT 186
Cdd:pfam00005 149 TA 150
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 297-525 9.33e-37

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 138.30  E-value: 9.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDp 371
Cdd:COG1125    13 DGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTT----LRMINrliepTSGRILIDGE---DIRDLDPVELRRRIGYVIQQ- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 fGSLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDPET-RHRYPHEFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:COG1125    85 -IGLFPHMTVAENIATVPRLLGW-DKERIRARVDELLELVGLDPEEyRDRYPHELSGGQQQRVGVARALAADPPILLMDE 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDL--AVvkALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLL 525
Cdd:COG1125   163 PFGALDPITREQLQDELLRLQRELGKTIVFVTHDIdeAL--KLGDRIAVMREGRIVQYDTPEEILANPANDFVADFV 237
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 6-253 9.49e-37

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 139.46  E-value: 9.49e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLpYPLARHPSGTIEYSGQNLLNLK-E 84
Cdd:COG3842     5 ALELENVSKRY--GD--VTALDDVSLSIEPGEFVALLGPSGCGKTTL----LRMI-AGFETPDSGRILLDGRDVTGLPpE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KtirhiRGnrIAMIFQEP-----MTSL-N---PLHsiekqinevlgiHKGLIGKVATKRTLELLEMVGIPEPEKRLkalP 155
Cdd:COG3842    76 K-----RN--VGMVFQDYalfphLTVAeNvafGLR------------MRGVPKAEIRARVAELLELVGLEGLADRY---P 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLN--LVkrIAHRVCVMQR 233
Cdd:COG3842   134 HQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEeaLA--LADRIAVMND 211

                         250       260
                  ....*....|....*....|
gi 1834229548 234 GCIVEQASCEQLFRAPQHPY 253
Cdd:COG3842   212 GRIEQVGTPEEIYERPATRF 231
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 305-507 1.79e-36

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 134.73  E-value: 1.79e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPqGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSlTQQQVR--PLRREMQVVFQDpfGSLSP 377
Cdd:cd03297    17 IDFDLN-EEVTGIFGASGAGKSTL----LRCIAglekpDGGTIVLNGTVLFD-SRKKINlpPQQRKIGLVFQQ--YALFP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEGLRIHKMGTEAEQEQAIIAALkevGLDPETRhRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:cd03297    89 HLNVRENLAFGLKRKRNREDRISVDELLDLL---GLDHLLN-RYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDR 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1834229548 458 TVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03297   165 ALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
300-507 2.15e-36

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 142.61  E-value: 2.15e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPF---GSl 375
Cdd:COG1132   354 PVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYdPTSGRILIDGVDIRDLTLES---LRRQIGVVPQDTFlfsGT- 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 sprmcvsqiVGEGLRIHKMG-TEAEqeqaIIAALKEVGLDPETRhRYPH-----------EFSGGQRQRIAIARALVLKP 443
Cdd:COG1132   430 ---------IRENIRYGRPDaTDEE----VEEAAKAAQAHEFIE-ALPDgydtvvgergvNLSGGQRQRIAIARALLKDP 495

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 444 ALILLDEPTSALD----RTVQRQVVELLRslqskyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:COG1132   496 PILILDEATSALDteteALIQEALERLMK------GRTTIVIAHRLSTIRN-ADRILVLDDGRIVEQG 556
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 272-517 2.84e-36

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 135.55  E-value: 2.84e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 272 GPPMLTVEDLKVWFpikKGLlkktvdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEG 346
Cdd:COG0411     1 SDPLLEVRGLTKRF---GGL--------VAVDDVSLEVERGEIVGLIGPNGAGKTTL----FNLITgfyrpTSGRILFDG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 347 KQLDSLTQQQV--RPLRRemqvVFQDP--FGSLSPRMCV---------SQIVGEGLRIHKMG-TEAEQEQAIIAALKEVG 412
Cdd:COG0411    66 RDITGLPPHRIarLGIAR----TFQNPrlFPELTVLENVlvaaharlgRGLLAALLRLPRARrEEREARERAEELLERVG 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 413 LDPEtRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALS 492
Cdd:COG0411   142 LADR-ADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLA 220

                         250       260
                  ....*....|....*....|....*
gi 1834229548 493 HQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:COG0411   221 DRIVVLDFGRVIAEGTPAEVRADPR 245
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 7-258 3.23e-36

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 137.97  E-value: 3.23e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLlnlkeKT 86
Cdd:COG1118     3 IEVRNISKRF--GSF--TLLDDVSLEIASGELVALLGPSGSGKT----TLLRII-AGLETPDSGRIVLNGRDL-----FT 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGNRIAMIFQEP-----MTslnplhsiekqineVL-----GIHKGLIGKVATK-RTLELLEMVGIPEPEKRLkalP 155
Cdd:COG1118    69 NLPPRERRVGFVFQHYalfphMT--------------VAeniafGLRVRPPSKAEIRaRVEELLELVQLEGLADRY---P 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGC 235
Cdd:COG1118   132 SQLSGGQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGR 211

                         250       260
                  ....*....|....*....|...
gi 1834229548 236 IVEQASCEQLFRAPQHPYTRELL 258
Cdd:COG1118   212 IEQVGTPDEVYDRPATPFVARFL 234
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 305-517 4.09e-36

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 134.76  E-value: 4.09e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLgLAILRL--IGSKGGIRFEGKQLD---SLTQQQVRPLRREMQVVFQDPfgSLSPRM 379
Cdd:PRK11124   21 ITLDCPQGETLVLLGPSGAGKSSL-LRVLNLleMPRSGTLNIAGNHFDfskTPSDKAIRELRRNVGMVFQQY--NLWPHL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 CVSQIVGEG-LRIHKMGTEAEQEQAIiAALKEVGLDPETrHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:PRK11124   98 TVQQNLIEApCRVLGLSKDQALARAE-KLLERLRLKPYA-DRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 459 VQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSiFAAPQ 517
Cdd:PRK11124  176 ITAQIVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC-FTQPQ 232
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 1-260 4.95e-36

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 135.05  E-value: 4.95e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVVGERCQrvveGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLArhPS-GTIEYSGQ-- 77
Cdd:PRK11701    1 MMDQPLLSVRGLTKLYGPRKGCR----DVSFDLYPGEVLGIVGESGSGKT----TLLNALSARLA--PDaGEVHYRMRdg 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  78 ---NLLNLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVL-GI---HKGLIGKVATkrtlELLEMVGIPEpeKR 150
Cdd:PRK11701   71 qlrDLYALSEAERRRLLRTEWGFVHQHPRDGLRMQVSAGGNIGERLmAVgarHYGDIRATAG----DWLERVEIDA--AR 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 151 LKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCV 230
Cdd:PRK11701  145 IDDLPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLV 224

                         250       260       270
                  ....*....|....*....|....*....|
gi 1834229548 231 MQRGCIVEQASCEQLFRAPQHPYTRELLAA 260
Cdd:PRK11701  225 MKQGRVVESGLTDQVLDDPQHPYTQLLVSS 254
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 295-501 7.75e-36

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 133.04  E-value: 7.75e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 295 TVDY--VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKqldSLTQQQVR----PLRREMQVV 367
Cdd:cd03235     6 TVSYggHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLkPTSGSIRVFGK---PLEKERKRigyvPQRRSIDRD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 368 FqdpfgslspRMCVSQIVGEGLRIHK---MGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPA 444
Cdd:cd03235    83 F---------PISVRDVVLMGLYGHKglfRRLSKADKAKVDEALERVGLS-ELADRQIGELSGGQQQRVLLARALVQDPD 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 445 LILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQG 501
Cdd:cd03235   153 LLLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLLNRT 208
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 3-240 8.00e-36

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 133.33  E-value: 8.00e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   3 QDNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNL 82
Cdd:COG4181     5 SAPIIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKS----TLLGLLA-GLDRPTSGTVRLAGQDLFAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 KEKTIRHIRGNRIAMIFQE----P-MTSL-N---PLhsiekqinEVLGihkgliGKVATKRTLELLEMVGIpepEKRLKA 153
Cdd:COG4181    80 DEDARARLRARHVGFVFQSfqllPtLTALeNvmlPL--------ELAG------RRDARARARALLERVGL---GHRLDH 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 154 LPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQR 233
Cdd:COG4181   143 YPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRA 221


                  ....*..
gi 1834229548 234 GCIVEQA 240
Cdd:COG4181   222 GRLVEDT 228
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
303-526 8.09e-36

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 133.68  E-value: 8.09e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSlTQQQVRPLRREMQVVFQDpFgSLSP 377
Cdd:PRK09493   18 HNIDLNIDQGEVVVIIGPSGSGKSTL----LRCINkleeiTSGDLIVDGLKVND-PKVDERLIRQEAGMVFQQ-F-YLFP 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEG-LRIHKMGTEAEQEQAIiAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PRK09493   91 HLTALENVMFGpLRVRGASKEEAEKQAR-ELLAKVGLA-ERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALD 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 457 RTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLE 526
Cdd:PRK09493  169 PELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFLQ 237
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-236 9.37e-36

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 133.68  E-value: 9.37e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLl 80
Cdd:COG1121     1 MMMMPAIELENLTVSY--GGR--PVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLP-PT----SGTVRLFGKPP- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 nlkektirHIRGNRIAMIFQE-------PMTSLnplhsiekqinEV--LGI--HKGL---IGKVATKRTLELLEMVGIPE 146
Cdd:COG1121    71 --------RRARRRIGYVPQRaevdwdfPITVR-----------DVvlMGRygRRGLfrrPSRADREAVDEALERVGLED 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 147 PEKRlkalP-HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIA 225
Cdd:COG1121   132 LADR----PiGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYF 206

                         250
                  ....*....|.
gi 1834229548 226 HRVCVMQRGCI 236
Cdd:COG1121   207 DRVLLLNRGLV 217
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 273-529 1.29e-35

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 133.62  E-value: 1.29e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWFpikkGllKKtvdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLR-------LIGS---KGGI 342
Cdd:COG1117     9 EPKIEVRNLNVYY----G--DK-----QALKDINLDIPENKVTALIGPSGCGKSTL----LRclnrmndLIPGarvEGEI 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 343 RFEGKQLDSLTQQQVRpLRREMQVVFQ--DPFgslsPrMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHR 420
Cdd:COG1117    74 LLDGEDIYDPDVDVVE-LRRRVGMVFQkpNPF----P-KSIYDNVAYGLRLHGIKSKSELDEIVEESLRKAALWDEVKDR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 421 ---YPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYnlTYLFISHDLAVVKALSHQLMV 497
Cdd:COG1117   148 lkkSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDY--TIVIVTHNMQQAARVSDYTAF 225

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1834229548 498 VKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAF 529
Cdd:COG1117   226 FYLGELVEFGPTEQIFTNPKDKRTEDYITGRF 257
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
274-527 1.35e-35

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 135.70  E-value: 1.35e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAI-------LRLIGSKggIRFEG 346
Cdd:PRK15093    2 PLLDIRNLTIEFKTSDG-------WVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAIcgvtkdnWRVTADR--MRFDD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 347 KQLDSLTQQQVRPL-RREMQVVFQDPFGSLSP-----RMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGL-DP-ETR 418
Cdd:PRK15093   73 IDLLRLSPRERRKLvGHNVSMIFQEPQSCLDPservgRQLMQNIPGWTYKGRWWQRFGWRKRRAIELLHRVGIkDHkDAM 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 419 HRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVV 498
Cdd:PRK15093  153 RSFPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVL 232

                         250       260
                  ....*....|....*....|....*....
gi 1834229548 499 KQGQVVEQGDAQSIFAAPQHPYTQQLLEA 527
Cdd:PRK15093  233 YCGQTVETAPSKELVTTPHHPYTQALIRA 261
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 7-234 1.44e-35

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 131.16  E-value: 1.44e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLlNLKEKT 86
Cdd:cd03229     1 LELKNVSKRY--GQK--TVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLE-----EPDSGSILIDGEDL-TDLEDE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgNRIAMIFQEPmtSLNPlhsiekqinevlgihkgligkvatkrTLELLEMVGIPepekrlkalpheLSGGQRQRV 166
Cdd:cd03229    71 LPPLR-RRIGMVFQDF--ALFP--------------------------HLTVLENIALG------------LSGGQQQRV 109

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 167 MIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd03229   110 ALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDG 177
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 302-507 1.58e-35

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 131.02  E-value: 1.58e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQvrpLRREMQVVFQdpfgslsprmc 380
Cdd:cd03214    15 LDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGeILLDGKDLASLSPKE---LARKIAYVPQ----------- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 vsqivgeglrihkmgteaeqeqaiiaALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQ 460
Cdd:cd03214    81 --------------------------ALELLGLA-HLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQ 133

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 461 RQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03214   134 IELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 305-534 1.74e-35

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 136.00  E-value: 1.74e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQL-DSLTQQQVRPLRREMQVVFQDPfgSLSPR 378
Cdd:COG4148    18 VDFTLPGRGVTALFGPSGSGKTTL----LRAIAglerpDSGRIRLGGEVLqDSARGIFLPPHRRRIGYVFQEA--RLFPH 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSQIVGEGLRIHKMGTEAEQEQAIIAALkevGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:COG4148    92 LSVRGNLLYGRKRAPRAERRISFDEVVELL---GIGH-LLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 459 VQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAFLVPAT 534
Cdd:COG4148   168 RKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPLAGGEEAGSVLEAT 243
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 299-517 2.58e-35

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 132.18  E-value: 2.58e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRplRREMQVVFQDP-- 371
Cdd:cd03219    13 LVALDDVSFSVRPGEIHGLIGPNGAGKTTL----FNLISgflrpTSGSVLFDGEDITGLPPHEIA--RLGIGRTFQIPrl 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 FGSLSPR--MCVSQIVGEGLRIH---KMGTEAEQEQAIIAALKEVGLDPEtRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03219    87 FPELTVLenVMVAAQARTGSGLLlarARREEREARERAEELLERVGLADL-ADRPAGELSYGQQRRLEIARALATDPKLL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:cd03219   166 LLDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPR 235
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 294-507 2.91e-35

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 131.22  E-value: 2.91e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 294 KTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDsltqqQVRPLRREMQVVF 368
Cdd:cd03301     8 KRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTT----LRMIAgleepTSGRIYIGGRDVT-----DLPPKDRDIAMVF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILL 448
Cdd:cd03301    79 QNY--ALYPHMTVYDNIAFGLKLRKVP-KDEIDERVREVAELLQIE-HLLDRKPKQLSGGQRQRVALGRAIVREPKVFLM 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 449 DEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03301   155 DEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 302-527 3.08e-35

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 132.52  E-value: 3.08e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIgsKGGIRFEGKQLdSLTQQQVRP--LR-REMQVVFQDPFGSLSPr 378
Cdd:PRK10418   19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGIL--PAGVRQTAGRV-LLDGKPVAPcaLRgRKIATIMQNPRSAFNP- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 mcvsqivgeglrIHKMGTEAEQ----------EQAIIAALKEVGLDPETR--HRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:PRK10418   95 ------------LHTMHTHAREtclalgkpadDATLTAALEAVGLENAARvlKLYPFEMSGGMLQRMMIALALLCEAPFI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLE 526
Cdd:PRK10418  163 IADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVS 242


                  .
gi 1834229548 527 A 527
Cdd:PRK10418  243 A 243
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 255-526 4.09e-35

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 138.75  E-value: 4.09e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 255 RELLAAEPSGT-PATNVVGP--PMLTVEDLkvwfpikkgllkkTVDY----VKAVDGINFSLPQGQTLGIVGESGSGKST 327
Cdd:COG4987   310 NELLDAPPAVTePAEPAPAPggPSLELEDV-------------SFRYpgagRPVLDGLSLTLPPGERVAIVGPSGSGKST 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 328 LGLAILRLIGSKGG-IRFEGKQLDSLTQQQvrpLRREMQVVFQDP--FgslsprmcvSQIVGEGLRIhkmGTEAEQEQAI 404
Cdd:COG4987   377 LLALLLRFLDPQSGsITLGGVDLRDLDEDD---LRRRIAVVPQRPhlF---------DTTLRENLRL---ARPDATDEEL 441

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 405 IAALKEVGLDPETRhRYPH-----------EFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRS-LQS 472
Cdd:COG4987   442 WAALERVGLGDWLA-ALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEaLAG 520

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 473 KynlTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAapQHPYTQQLLE 526
Cdd:COG4987   521 R---TVLLITHRLAGL-ERMDRILVLEDGRIVEQGTHEELLA--QNGRYRQLYQ 568
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 23-250 4.94e-35

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 132.58  E-value: 4.94e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYSGQNLLNLKEKTIRHIRgNRIAM 97
Cdd:TIGR04521  18 KKALDDVSLTIEDGEFVAIIGHTGSGKS----TLIQHLngllkPT------SGTVTIDGRDITAKKKKKLKDLR-KKVGL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  98 IFQEPmtslnplhsiEKQINEVLgIHK---------GLIGKVATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQRVMI 168
Cdd:TIGR04521  87 VFQFP----------EHQLFEET-VYKdiafgpknlGLSEEEAEERVKEALELVGLDE--EYLERSPFELSGGQMRRVAI 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 169 AMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRA 248
Cdd:TIGR04521 154 AGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSD 233


                  ..
gi 1834229548 249 PQ 250
Cdd:TIGR04521 234 VD 235
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 317-520 1.44e-34

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 132.62  E-value: 1.44e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 317 IVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLdsltqQQVRPLRREMQVVFQDPfgSLSPRMCVSQIVGEGLRI 391
Cdd:TIGR01187   1 LLGPSGCGKTTL----LRLLAgfeqpDSGSIMLDGEDV-----TNVPPHLRHINMVFQSY--ALFPHMTVEENVAFGLKM 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 392 HKMGTEaEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQ 471
Cdd:TIGR01187  70 RKVPRA-EIKPRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQ 147

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1834229548 472 SKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPY 520
Cdd:TIGR01187 148 EQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLF 196
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 302-535 1.55e-34

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 133.58  E-value: 1.55e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI---GSKGGIRFEGKQLDSLTqqqvrPLRREMQVVFQDPfgSLSPR 378
Cdd:TIGR03258  21 LDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVkaaGLTGRIAIADRDLTHAP-----PHKRGLALLFQNY--ALFPH 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:TIGR03258  94 LKVEDNVAFGLRAQKM-PKADIAERVADALKLVGLG-DAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEPLSALDAN 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 459 VQRQVVELLRSLQSKY-NLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAFLVPATA 535
Cdd:TIGR03258 172 IRANMREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFLGAANILPAIA 249
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
4-260 1.59e-34

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 131.07  E-value: 1.59e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGE---RCQRV--VEGVSFDIKRGETLALVGESGSGKSVtahsilrllpypLARHPSGTIEYSGQN 78
Cdd:PRK15112    2 ETLLEVRNLSKTFRYRTgwfRRQTVeaVKPLSFTLREGQTLAIIGENGSGKST------------LAKMLAGMIEPTSGE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 LLnLKEKTIR----HIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGI-PEpekRLKA 153
Cdd:PRK15112   70 LL-IDDHPLHfgdySYRSQRIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLlPD---HASY 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 154 LPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQR 233
Cdd:PRK15112  146 YPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQ 225

                         250       260
                  ....*....|....*....|....*..
gi 1834229548 234 GCIVEQASCEQLFRAPQHPYTRELLAA 260
Cdd:PRK15112  226 GEVVERGSTADVLASPLHELTKRLIAG 252
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 6-238 2.05e-34

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 129.39  E-value: 2.05e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHsILRLLPYPlarhPSGTIEYSGQNLLNLKEK 85
Cdd:TIGR02211   1 LLKCENLGKRYQEGKLDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLH-LLGGLDNP----TSGEVLFNGQSLSKLSSN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQ--EPMTSLNPLHSIEKQInevlgihkgLIGKV----ATKRTLELLEMVGIpepEKRLKALPHELS 159
Cdd:TIGR02211  76 ERAKLRNKKLGFIYQfhHLLPDFTALENVAMPL---------LIGKKsvkeAKERAYEMLEKVGL---EHRINHRPSELS 143

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAhRVCVMQRGCIVE 238
Cdd:TIGR02211 144 GGERQRVAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKLD-RVLEMKDGQLFN 221
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
292-516 2.21e-34

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 133.53  E-value: 2.21e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTlglaILRLIG-----SKGGIRFEGKQLDsltqqQVRPLRREMQV 366
Cdd:PRK09452   20 ISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTT----VLRLIAgfetpDSGRIMLDGQDIT-----HVPAENRHVNT 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:PRK09452   91 VFQSY--ALFPHMTVFENVAFGLRMQKTP-AAEITPRVMEALRMVQLE-EFAQRKPHQLSGGQQQRVAIARAVVNKPKVL 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:PRK09452  167 LLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEP 236
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 8-239 3.24e-34

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 127.17  E-value: 3.24e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLLNLKEKTI 87
Cdd:cd03214     1 EVENLSVGY--GGR--TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLK-PS----SGEILLDGKDLASLSPKEL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  88 RhirgNRIAMIFQEpMTSLNPLHSIEKQINEvlgihkgligkvatkrtlellemvgipepekrlkalpheLSGGQRQRVM 167
Cdd:cd03214    72 A----RKIAYVPQA-LELLGLAHLADRPFNE---------------------------------------LSGGERQRVL 107

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 168 IAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ 239
Cdd:cd03214   108 LARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQ 179
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 7-245 3.34e-34

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 129.22  E-value: 3.34e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERcqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLKEK 85
Cdd:cd03256     1 IEVENLSKTYPNGKK---ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVE------PtSGSVLIDGTDINKLKGK 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGnRIAMIFQ-----EPMTSL-NPLHSIEKQINEVLGIhKGLIGKVATKRTLELLEMVGIPE-PEKRLKalphEL 158
Cdd:cd03256    72 ALRQLRR-QIGMIFQqfnliERLSVLeNVLSGRLGRRSTWRSL-FGLFPKEEKQRALAALERVGLLDkAYQRAD----QL 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVE 238
Cdd:cd03256   146 SGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVF 225


                  ....*..
gi 1834229548 239 QASCEQL 245
Cdd:cd03256   226 DGPPAEL 232
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
304-525 6.31e-34

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 129.15  E-value: 6.31e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLT----------QQQVRPLRREMQVVF 368
Cdd:COG4598    26 GVSLTARKGDVISIIGSSGSGKSTF----LRCINlletpDSGEIRVGGEEIRLKPdrdgelvpadRRQLQRIRTRLGMVF 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDpFgSLSPRMCVSQIVGEG-LRIHKMGTEAEQEQAIiAALKEVGLdPETRHRYPHEFSGGQRQRIAIARALVLKPALIL 447
Cdd:COG4598   102 QS-F-NLWSHMTVLENVIEApVHVLGRPKAEAIERAE-ALLAKVGL-ADKRDAYPAHLSGGQQQRAAIARALAMEPEVML 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 448 LDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLL 525
Cdd:COG4598   178 FDEPTSALDPELVGEVLKVMRDLAEEGR-TMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNPKSERLRQFL 254
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
301-527 9.36e-34

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 129.36  E-value: 9.36e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLdslTQQQVRPLRREMQVVFQDPfgslsprm 379
Cdd:PRK13635   22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLpEAGTITVGGMVL---SEETVWDVRRQVGMVFQNP-------- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 cVSQIVGE--------GLRIHKMGTEAEQEQaIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:PRK13635   91 -DNQFVGAtvqddvafGLENIGVPREEMVER-VDQALRQVGME-DFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 452 TSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAAPQH--------PYTQQ 523
Cdd:PRK13635  168 TSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEILEEGTPEEIFKSGHMlqeigldvPFSVK 246


                  ....
gi 1834229548 524 LLEA 527
Cdd:PRK13635  247 LKEL 250
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 24-528 1.01e-33

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 133.80  E-value: 1.01e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyplARHPSGTieYSGQNLLNLKEKTIRHIRGNR---IAMIFQ 100
Cdd:TIGR02633  15 KALDGIDLEVRPGECVGLCGENGAGKS----TLMKILS---GVYPHGT--WDGEIYWSGSPLKASNIRDTEragIVIIHQ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 101 EPMtsLNPLHSIEKQI---NEVlgIHKGLIGKVA--TKRTLELLEMVGIPE-PEKRLKAlphELSGGQRQRVMIAMALAN 174
Cdd:TIGR02633  86 ELT--LVPELSVAENIflgNEI--TLPGGRMAYNamYLRAKNLLRELQLDAdNVTRPVG---DYGGGQQQLVEIAKALNK 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 175 EPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIV--EQASCEQLFRAPQHP 252
Cdd:TIGR02633 159 QARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHVatKDMSTMSEDDIITMM 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 253 YTRELLAAEPSgTPATnvVGPPMLTVEDLKVWFPIKKgllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaI 332
Cdd:TIGR02633 238 VGREITSLYPH-EPHE--IGDVILEARNLTCWDVINP--------HRKRVDDVSFSLRRGEILGVAGLVGAGRTEL---V 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 333 LRLIGS-----KGGIRFEGKQLDSLTQQQVrpLRREMQVVFQD-PFGSLSPRMCVSQ-IVGEGL-RIHKMGT--EAEQEQ 402
Cdd:TIGR02633 304 QALFGAypgkfEGNVFINGKPVDIRNPAQA--IRAGIAMVPEDrKRHGIVPILGVGKnITLSVLkSFCFKMRidAAAELQ 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 403 AIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFIS 482
Cdd:TIGR02633 382 IIGSAIQRLKVKTASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVS 460

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 483 HDLAVVKALSHQLMVVKQGQVveQGDAQSifaapqHPYTQ-QLLEAA 528
Cdd:TIGR02633 461 SELAEVLGLSDRVLVIGEGKL--KGDFVN------HALTQeQVLAAA 499
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 24-528 1.57e-33

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 133.52  E-value: 1.57e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSVtahsilrLLPYPLARHPSGTieYSGQNLLNLKEKTIRHIRGNR---IAMIFQ 100
Cdd:PRK13549   19 KALDNVSLKVRAGEIVSLCGENGAGKST-------LMKVLSGVYPHGT--YEGEIIFEGEELQASNIRDTEragIAIIHQ 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 101 EPMtsLNPLHSIEKQI---NEVLgiHKGLIGKVA-TKRTLELLEMVGIP-EPEKRLKalphELSGGQRQRVMIAMALANE 175
Cdd:PRK13549   90 ELA--LVKELSVLENIflgNEIT--PGGIMDYDAmYLRAQKLLAQLKLDiNPATPVG----NLGLGQQQLVEIAKALNKQ 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 176 PELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLfrapqhpyT- 254
Cdd:PRK13549  162 ARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGM--------Te 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 255 ---------RELLAAEPSgtpATNVVGPPMLTVEDLKVWFPIKKGllkktvdyVKAVDGINFSLPQGQTLGIVGESGSGK 325
Cdd:PRK13549  233 ddiitmmvgRELTALYPR---EPHTIGEVILEVRNLTAWDPVNPH--------IKRVDDVSFSLRRGEILGIAGLVGAGR 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 326 STLGLAILrliG-----SKGGIRFEGKQLDSLTQQQVrpLRREMQVVFQD--PFGsLSPRMCVSQ-IVGEGL-RIHKMGT 396
Cdd:PRK13549  302 TELVQCLF---GaypgrWEGEIFIDGKPVKIRNPQQA--IAQGIAMVPEDrkRDG-IVPVMGVGKnITLAALdRFTGGSR 375

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 397 --EAEQEQAIIAALKEVgldpetRHRYPHEF------SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLR 468
Cdd:PRK13549  376 idDAAELKTILESIQRL------KVKTASPElaiarlSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLIN 449

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 469 SLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVveQGDaqsifaAPQHPYTQ-QLLEAA 528
Cdd:PRK13549  450 QL-VQQGVAIIVISSELPEVLGLSDRVLVMHEGKL--KGD------LINHNLTQeQVMEAA 501
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 274-511 2.81e-33

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 126.39  E-value: 2.81e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPIKKGLLKktvdyvkAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQ 348
Cdd:COG4181     7 PIIELRGLTKTVGTGAGELT-------ILKGISLEVEAGESVAIVGASGSGKSTL----LGLLAgldrpTSGTVRLAGQD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDSLTQQQVRPLRRE-MQVVFQDpFgSLSPRMCVSQIVG---EgLRIHKmgtEAEQEQAiiAALKEVGLDPETRHrYPHE 424
Cdd:COG4181    76 LFALDEDARARLRARhVGFVFQS-F-QLLPTLTALENVMlplE-LAGRR---DARARAR--ALLERVGLGHRLDH-YPAQ 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 425 FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVkALSHQLMVVKQGQVV 504
Cdd:COG4181   147 LSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALA-ARCDRVLRLRAGRLV 225


                  ....*..
gi 1834229548 505 EQGDAQS 511
Cdd:COG4181   226 EDTAATA 232
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
7-236 3.26e-33

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 125.70  E-value: 3.26e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKT 86
Cdd:COG4619     1 LELEGLSFRV----GGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPT-----SGEIYLDGKPLSAMPPPE 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHirgnRIAMIFQEPmtslnPL--HSIEKQINEVLGIHKGligKVATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQ 164
Cdd:COG4619    72 WRR----QVAYVPQEP-----ALwgGTVRDNLPFPFQLRER---KFDRERALELLERLGLPP--DILDKPVERLSGGERQ 137

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCI 236
Cdd:COG4619   138 RLALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 274-529 5.96e-33

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 126.43  E-value: 5.96e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPIKKgllkktvdyvkAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRL------IGSKGGIRFEGK 347
Cdd:PRK14239    4 PILQVSDLSVYYNKKK-----------ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpeVTITGSIVYNGH 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 348 QLDSLTQQQVRpLRREMQVVFQDPfgslSP-RMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYpHE-- 424
Cdd:PRK14239   73 NIYSPRTDTVD-LRKEIGMVFQQP----NPfPMSIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASIWDEVKDRL-HDsa 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 425 --FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYnlTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:PRK14239  147 lgLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGD 224

                         250       260
                  ....*....|....*....|....*..
gi 1834229548 503 VVEQGDAQSIFAAPQHPYTQQLLEAAF 529
Cdd:PRK14239  225 LIEYNDTKQMFMNPKHKETEDYISGKF 251
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 5-258 9.34e-33

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 125.63  E-value: 9.34e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlRLLPYPLA-RHPSGTIEYSGQNLLNLK 83
Cdd:PRK11264    2 SAIEVKNLVKKF----HGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCI-NLLEQPEAgTIRVGDITIDTARSLSQQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRgNRIAMIFQEpmTSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKrlkALPHELSGGQR 163
Cdd:PRK11264   77 KGLIRQLR-QHVGFVFQN--FNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKET---SYPRRLSGGQQ 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVT-VQLKILELLKELQARLGMalLLISHDLNLVKRIAHRVCVMQRGCIVEQASC 242
Cdd:PRK11264  151 QRVAIARALAMRPEVILFDEPTSALDPElVGEVLNTIRQLAQEKRTM--VIVTHEMSFARDVADRAIFMDQGRIVEQGPA 228

                         250
                  ....*....|....*.
gi 1834229548 243 EQLFRAPQHPYTRELL 258
Cdd:PRK11264  229 KALFADPQQPRTRQFL 244
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 292-503 9.55e-33

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 122.89  E-value: 9.55e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSltqqQVRPLRREMQV 366
Cdd:cd03230     6 LSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTL----IKIILgllkpDSGEIKVLGKDIKK----EPEEVKRRIGY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVgeglrihkmgteaeqeqaiiaalkevgldpetrhryphEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03230    78 LPEEP--SLYENLTVRENL--------------------------------------KLSGGMKQRLALAQALLHDPELL 117

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:cd03230   118 ILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 292-502 9.69e-33

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 122.74  E-value: 9.69e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKqldSLTQQQVRPLRREMQVVFQd 370
Cdd:cd00267     5 LSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGeILIDGK---DIAKLPLEELRRRIGYVPQ- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 371 pfgslsprmcvsqivgeglrihkmgteaeqeqaiiaalkevgldpetrhrypheFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:cd00267    81 ------------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDE 106

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:cd00267   107 PTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 274-529 1.00e-32

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 125.65  E-value: 1.00e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVwfpiKKGllKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-----GSKGGIRFEGKQ 348
Cdd:PRK13548    1 AMLEARNLSV----RLG--GRTL-----LDDVSLTLRPGEVVAILGPNGAGKSTL----LRALsgelsPDSGEVRLNGRP 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDSLTQQQvRPLRREM-----QVVFqdPFGslsprmcVSQIVGEGLRIHKmGTEAEQEQAIIAALKEVGLDpETRHRYPH 423
Cdd:PRK13548   66 LADWSPAE-LARRRAVlpqhsSLSF--PFT-------VEEVVAMGRAPHG-LSRAEDDALVAAALAQVDLA-HLAGRDYP 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 424 EFSGGQRQRIAIARALV------LKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMV 497
Cdd:PRK13548  134 QLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVL 213

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1834229548 498 VKQGQVVEQGdaqsifaAPQHPYTQQLLEAAF 529
Cdd:PRK13548  214 LHQGRLVADG-------TPAEVLTPETLRRVY 238
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 7-246 1.48e-32

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 125.62  E-value: 1.48e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERcqRVVEGVSFDIKRGETLALVGESGSGKSvTahsilrllpypLARH------P-SGTIEYSGQNL 79
Cdd:TIGR04520   1 IEVENVSFSYPESEK--PALKNVSLSIEKGEFVAIIGHNGSGKS-T-----------LAKLlnglllPtSGKVTVDGLDT 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  80 LNlkEKTIRHIRgNRIAMIFQepmtslNPlhsiEKQI------NEV------LGIHKGLIGKvatkRTLELLEMVGIpep 147
Cdd:TIGR04520  67 LD--EENLWEIR-KKVGMVFQ------NP----DNQFvgatveDDVafglenLGVPREEMRK----RVDEALKLVGM--- 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 148 EKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLN-LVKriAH 226
Cdd:TIGR04520 127 EDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEeAVL--AD 204

                         250       260
                  ....*....|....*....|
gi 1834229548 227 RVCVMQRGCIVEQASCEQLF 246
Cdd:TIGR04520 205 RVIVMNKGKIVAEGTPREIF 224
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 305-520 1.64e-32

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 127.54  E-value: 1.64e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQL-DSLTQQQVRPLRREMQVVFQDpfGSLSPRMCVS 382
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGeIVLNGRTLfDSRKGIFLPPEKRRIGYVFQE--ARLFPHLSVR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 383 QIVGEGLRihkmGTEAEQEQAIIAALKEV-GLDPETRhRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQR 461
Cdd:TIGR02142  94 GNLRYGMK----RARPSERRISFERVIELlGIGHLLG-RLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKY 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 462 QVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPY 520
Cdd:TIGR02142 169 EILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW 227
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 301-513 2.25e-32

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 125.25  E-value: 2.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLG-LAILRLIGSKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDP----FGSL 375
Cdd:PRK13648   24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAkLMIGIEKVKSGEIFYNNQ---AITDDNFEKLRKHIGIVFQNPdnqfVGSI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 sprmcVSQIVGEGLRIHKMGTEAEQEQaIIAALKEVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:PRK13648  101 -----VKYDVAFGLENHAVPYDEMHRR-VSEALKQVDMLERADYE-PNALSGGQKQRVAIAGVLALNPSVIILDEATSML 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAvvKAL-SHQLMVVKQGQVVEQGDAQSIF 513
Cdd:PRK13648  174 DPDARQNLLDLVRKVKSEHNITIISITHDLS--EAMeADHVIVMNKGTVYKEGTPTEIF 230
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 283-507 2.81e-32

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 123.49  E-value: 2.81e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 283 VWFPIKKGllkktvdyVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQvrpLR 361
Cdd:cd03254     8 VNFSYDEK--------KPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDpQKGQILIDGIDIRDISRKS---LR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 362 REMQVVFQDPFgsLSPRMCVSQIvgeglrihKMGTEAEQEQAIIAALKEVGLDPETRHR---YPHE-------FSGGQRQ 431
Cdd:cd03254    77 SMIGVVLQDTF--LFSGTIMENI--------RLGRPNATDEEVIEAAKEAGAHDFIMKLpngYDTVlgenggnLSQGERQ 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 432 RIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:cd03254   147 LLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEG 219
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 300-507 2.91e-32

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 123.88  E-value: 2.91e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTlglaILRLI-----GSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDpfgs 374
Cdd:cd03253    15 PVLKDVSFTIPAGKKVAIVGPSGSGKST----ILRLLfrfydVSSGSILIDGQDIREVTLDS---LRRAIGVVPQD---- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 lsprmCV--SQIVGEGLRihkMGTEAEQEQAIIAALKEVGLDPETRhRYPHEF-----------SGGQRQRIAIARALVL 441
Cdd:cd03253    84 -----TVlfNDTIGYNIR---YGRPDATDEEVIEAAKAAQIHDKIM-RFPDGYdtivgerglklSGGEKQRVAIARAILK 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 442 KPALILLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:cd03253   155 NPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERG 217
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 299-503 3.97e-32

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 122.90  E-value: 3.97e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDpfGSLSP 377
Cdd:cd03292    14 TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEElPTSGTIRVNGQDVSDLRGRAIPYLRRKIGVVFQD--FRLLP 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEGLRIHKMGTEAEQEQaIIAALKEVGLdpETRHR-YPHEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:cd03292    92 DRNVYENVAFALEVTGVPPREIRKR-VPAALELVGL--SHKHRaLPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLD 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 457 RTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:cd03292   169 PDTTWEIMNLLKKI-NKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
305-495 6.97e-32

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 122.62  E-value: 6.97e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRPLR-REMQVVFQdpFGSLSPR 378
Cdd:PRK11629   28 VSFSIGEGEMMAIVGSSGSGKSTL----LHLLGgldtpTSGDVIFNGQPMSKLSSAAKAELRnQKLGFIYQ--FHHLLPD 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:PRK11629  102 FTALENVAMPLLIGKKKPAEINSRAL-EMLAAVGLEHRANHR-PSELSGGERQRVAIARALVNNPRLVLADEPTGNLDAR 179

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1834229548 459 VQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQL 495
Cdd:PRK11629  180 NADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQL 216
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 9-505 7.92e-32

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 128.64  E-value: 7.92e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   9 VRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplarhpSGTIE-YSGqnllnlkekTI 87
Cdd:COG0488     1 LENLSKSF--GGR--PLLDDVSLSINPGDRIGLVGRNGAGKS----TLLKIL--------AGELEpDSG---------EV 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  88 RHIRGNRIAMIFQEP------------MTSLNPLHSIEKQINEV---LGIHKGLIGKVATK--------------RTLEL 138
Cdd:COG0488    56 SIPKGLRIGYLPQEPpldddltvldtvLDGDAELRALEAELEELeakLAEPDEDLERLAELqeefealggweaeaRAEEI 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 139 LEMVGIPEPEkrLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDV-TVqlkilellkelQ------ARLGMAL 211
Cdd:COG0488   136 LSGLGFPEED--LDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLeSI-----------EwleeflKNYPGTV 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 212 LLISHD---LNlvkRIAHRVCVMQRGCI-------------------VEQASCEQL-------------FRAPQHPYTR- 255
Cdd:COG0488   203 LVVSHDryfLD---RVATRILELDRGKLtlypgnysayleqraerleQEAAAYAKQqkkiakeeefirrFRAKARKAKQa 279

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 256 -----------ELLAAEPSGT-----PATNVVGPPMLTVEDLKVWFPikkgllKKTVdyvkaVDGINFSLPQGQTLGIVG 319
Cdd:COG0488   280 qsrikalekleREEPPRRDKTveirfPPPERLGKKVLELEGLSKSYG------DKTL-----LDDLSLRIDRGDRIGLIG 348

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 320 ESGSGKSTLglaiLRLIGSK----GGIRFEGKQLD--SLTQQQvrplrremqvvfqdpfGSLSPRMCVSQIVGEGLrihk 393
Cdd:COG0488   349 PNGAGKSTL----LKLLAGElepdSGTVKLGETVKigYFDQHQ----------------EELDPDKTVLDELRDGA---- 404

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 394 mgtEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDrtvqrqvVELLRSLQ-- 471
Cdd:COG0488   405 ---PGGTEQEVRGYLGRFLFSGDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLD-------IETLEALEea 474

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 1834229548 472 -SKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVE 505
Cdd:COG0488   475 lDDFPGTVLLVSHDRYFLDRVATRILEFEDGGVRE 509
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 6-237 8.92e-32

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 122.79  E-value: 8.92e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLKEK 85
Cdd:TIGR02315   1 MLEVENLSKVYPNG---KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLV-----EPSSGSILLEGTDITKLRGK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRgNRIAMIFQEpMTSLNPLHSIEKQINEVLGIHK------GLIGKVATKRTLELLEMVGIPE-PEKRLKalphEL 158
Cdd:TIGR02315  73 KLRKLR-RRIGMIFQH-YNLIERLTVLENVLHGRLGYKPtwrsllGRFSEEDKERALSALERVGLADkAYQRAD----QL 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:TIGR02315 147 SGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIV 225
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 29-260 1.09e-31

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 122.63  E-value: 1.09e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSVTAHSIL-RLLPyplarhPSGTIEY---SGQ--NLLNLKEKTIRHIRGNRIAMIFQEP 102
Cdd:TIGR02323  22 VSFDLYPGEVLGIVGESGSGKSTLLGCLAgRLAP------DHGTATYimrSGAelELYQLSEAERRRLMRTEWGFVHQNP 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNPLHSIEKQINEVL----GIHKGLIGKVATKrtleLLEMVGIPEpeKRLKALPHELSGGQRQRVMIAMALANEPEL 178
Cdd:TIGR02323  96 RDGLRMRVSAGANIGERLmaigARHYGNIRATAQD----WLEEVEIDP--TRIDDLPRAFSGGMQQRLQIARNLVTRPRL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 179 LIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELL 258
Cdd:TIGR02323 170 VFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTDQVLDDPQHPYTQLLV 249


                  ..
gi 1834229548 259 AA 260
Cdd:TIGR02323 250 SS 251
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 2-256 1.41e-31

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 122.45  E-value: 1.41e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYPLARHpSGTIEYSG 76
Cdd:COG1117     7 TLEPKIEVRNLNVYY--GDKQ--ALKDINLDIPENKVTALIGPSGCGKS----TLLRCLnrmndLIPGARV-EGEILLDG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  77 QNLLNLKEKTIRHIRgnRIAMIFQEPmtslNPL-HSIEKqiNEVLG--IHKgligkVATKRTL-----ELLEMVGIPEPE 148
Cdd:COG1117    78 EDIYDPDVDVVELRR--RVGMVFQKP----NPFpKSIYD--NVAYGlrLHG-----IKSKSELdeiveESLRKAALWDEV 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 149 K-RLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALD-----------------VTVqlkilellkelqarlgma 210
Cdd:COG1117   145 KdRLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDpistakieelilelkkdYTI------------------ 206

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1834229548 211 lLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRE 256
Cdd:COG1117   207 -VIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTNPKDKRTED 251
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 7-234 1.60e-31

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 119.80  E-value: 1.60e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLL-PYplarhpSGTIEYSGQNLLNLKEK 85
Cdd:cd03228     1 IEFKN--VSFSYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYdPT------SGEILIDGVDLRDLDLE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRhirgNRIAMIFQEPMtslnpLH--SIEKQInevlgihkgligkvatkrtlellemvgipepekrlkalpheLSGGQR 163
Cdd:cd03228    73 SLR----KNIAYVPQDPF-----LFsgTIRENI-----------------------------------------LSGGQR 102

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQlkILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRG 234
Cdd:cd03228   103 QRIAIARALLRDPPILILDEATSALDPETE--ALILEALRALAKGKTVIVIAHRLSTIRD-ADRIIVLDDG 170
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 300-504 1.80e-31

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 120.82  E-value: 1.80e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSltqqqvRPLRREMQVVFQDP---FGSL 375
Cdd:cd03226    14 EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGsILLNGKPIKA------KERRKSIGYVMQDVdyqLFTD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SprmcvsqiVGEGLRIHKMGTEAEQEQaIIAALKEVGL-DPETRHryPHEFSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:cd03226    88 S--------VREELLLGLKELDAGNEQ-AETVLKDLDLyALKERH--PLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSG 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1834229548 455 LDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:cd03226   157 LDYKNMERVGELIRELAAQGK-AVIVITHDYEFLAKVCDRVLLLANGAIV 205
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
304-529 1.94e-31

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 122.38  E-value: 1.94e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGK----------QLDSLTQQQVRPLRREMQVVF 368
Cdd:PRK10619   23 GVSLQANAGDVISIIGSSGSGKSTF----LRCINflekpSEGSIVVNGQtinlvrdkdgQLKVADKNQLRLLRTRLTMVF 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDpfGSLSPRMCVSQIVGEGlRIHKMG-TEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALIL 447
Cdd:PRK10619   99 QH--FNLWSHMTVLENVMEA-PIQVLGlSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARALAMEPEVLL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 448 LDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEA 527
Cdd:PRK10619  176 FDEPTSALDPELVGEVLRIMQQL-AEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKG 254


                  ..
gi 1834229548 528 AF 529
Cdd:PRK10619  255 SL 256
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 300-529 2.48e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 122.82  E-value: 2.48e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQLDSLT-QQQVRPLRREMQVVFQDPFG 373
Cdd:PRK13634   21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLlqhlnGL----LQPTSGTVTIGERVITAGKkNKKLKPLRKKVGIVFQFPEH 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SLsprmcVSQIVGEGLRIHKMG---TEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:PRK13634   97 QL-----FEETVEKDICFGPMNfgvSEEDAKQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDE 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQH--------PYT- 521
Cdd:PRK13634  172 PTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPDEleaigldlPETv 251

                         250
                  ....*....|
gi 1834229548 522 --QQLLEAAF 529
Cdd:PRK13634  252 kfKRALEEKF 261
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 8-234 4.50e-31

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 119.95  E-value: 4.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLLNlkekti 87
Cdd:cd03235     1 EVEDLTVSY--GGH--PVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLK-PT----SGSIRVFGKPLEK------ 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  88 rhiRGNRIAMIFQepmtslnpLHSIEKQ----INEVLGI----HKGLIGKVATK---RTLELLEMVGIPEPEKRLKAlph 156
Cdd:cd03235    66 ---ERKRIGYVPQ--------RRSIDRDfpisVRDVVLMglygHKGLFRRLSKAdkaKVDEALERVGLSELADRQIG--- 131

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 157 ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd03235   132 ELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLLNRT 208
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 28-234 6.88e-31

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 119.28  E-value: 6.88e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKTIRHIRgNRIAMIFQEpmTSLN 107
Cdd:TIGR02673  20 DVSLHIRKGEFLFLTGPSGAGKT----TLLKLL-YGALTPSRGQVRIAGEDVNRLRGRQLPLLR-RRIGVVFQD--FRLL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 108 PLHSIEKQIN---EVLGIHKGLIGKvatkRTLELLEMVGIPEpekRLKALPHELSGGQRQRVMIAMALANEPELLIADEP 184
Cdd:TIGR02673  92 PDRTVYENVAlplEVRGKKEREIQR----RVGAALRQVGLEH---KADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEP 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1834229548 185 TTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:TIGR02673 165 TGNLDPDLSERILDLLKRLNKR-GTTVIVATHDLSLVDRVAHRVIILDDG 213
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 297-515 1.03e-30

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 119.64  E-value: 1.03e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPFgsl 375
Cdd:cd03251    13 DGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDvDSGRILIDGHDVRDYTLAS---LRRQIGLVSQDVF--- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 sprmCVSQIVGEGLRIhkmGTEAEQEQAIIAALKEVGLdpetrhrypHEF-------------------SGGQRQRIAIA 436
Cdd:cd03251    87 ----LFNDTVAENIAY---GRPGATREEVEEAARAANA---------HEFimelpegydtvigergvklSGGQRQRIAIA 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 437 RALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:cd03251   151 RALLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTIEN-ADRIVVLEDGKIVERGTHEELLAQ 226
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 302-528 1.41e-30

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 119.56  E-value: 1.41e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQL---DSLTQQQVRPL--RREMQVVFQ--DPFgs 374
Cdd:PRK14267   20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNEEARVEGEVRlfgRNIYSPDVDPIevRREVGMVFQypNPF-- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 lsPRMCVSQIVGEGLRIHKM-GTEAEQEQAIIAALKEVGLDPETRHR---YPHEFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:PRK14267   98 --PHLTIYDNVAIGVKLNGLvKSKKELDERVEWALKKAALWDEVKDRlndYPSNLSGGQRQRLVIARALAMKPKILLMDE 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKYnlTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAA 528
Cdd:PRK14267  176 PTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELTEKYVTGA 251
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 28-234 1.56e-30

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 118.28  E-value: 1.56e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKTIRHIRgNRIAMIFQEpmTSLN 107
Cdd:cd03292    19 GINISISAGEFVFLVGPSGAGKS----TLLKLI-YKEELPTSGTIRVNGQDVSDLRGRAIPYLR-RKIGVVFQD--FRLL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 108 PLHSIEKQINEVLGIhKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTA 187
Cdd:cd03292    91 PDRNVYENVAFALEV-TGVPPREIRKRVPAALELVGL---SHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGN 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 188 LDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd03292   167 LDPDTTWEIMNLLKKINKA-GTTVVVATHAKELVDTTRHRVIALERG 212
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 301-507 1.90e-30

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 118.36  E-value: 1.90e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDPF---GSLs 376
Cdd:cd03244    19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVeLSSGSILIDGV---DISKIGLHDLRSRISIIPQDPVlfsGTI- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 pRmcvsqivgEGLRIHKMGTEAEqeqaIIAALKEVGLD-----PETRHRYPHE-----FSGGQRQRIAIARALVLKPALI 446
Cdd:cd03244    95 -R--------SNLDPFGEYSDEE----LWQALERVGLKefvesLPGGLDTVVEeggenLSVGQRQLLCLARALLRKSKIL 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:cd03244   162 VLDEATASVDPETDALIQKTIREAFK--DCTVLTIAHRLDTIID-SDRILVLDKGRVVEFD 219
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 7-236 2.35e-30

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 116.34  E-value: 2.35e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLL-PYplarhpSGTIEYSGQNLLNLKEK 85
Cdd:cd03230     1 IEVRNLSKRY--GKK--TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLkPD------SGEIKVLGKDIKKEPEE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRhirgnRIAMIFQEPMtslnplhsiekqinevlgIHKGLIGKvatkrtlELLEmvgipepekrlkalpheLSGGQRQR 165
Cdd:cd03230    71 VKR-----RIGYLPEEPS------------------LYENLTVR-------ENLK-----------------LSGGMKQR 103

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCI 236
Cdd:cd03230   104 LALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
cbiO PRK13637
energy-coupling factor transporter ATPase;
300-525 2.57e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 119.77  E-value: 2.57e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQldsLTQQQV--RPLRREMQVVFQDPF 372
Cdd:PRK13637   21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLiqhlnGL----LKPTSGKIIIDGVD---ITDKKVklSDIRKKVGLVFQYPE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 GSLSPRMcVSQIVGEGLRihKMG-TEAEQEQAIIAALKEVGLDPET-RHRYPHEFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:PRK13637   94 YQLFEET-IEKDIAFGPI--NLGlSEEEIENRVKRAMNIVGLDYEDyKDKSPFELSGGQKRRVAIAGVVAMEPKILILDE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIF-----------AAPQHP 519
Cdd:PRK13637  171 PTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFkevetlesiglAVPQVT 250


                  ....*.
gi 1834229548 520 YTQQLL 525
Cdd:PRK13637  251 YLVRKL 256
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
274-506 3.20e-30

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 118.81  E-value: 3.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFPikkgllkKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGkq 348
Cdd:COG4525     2 SMLTVRHVSVRYP-------GGGQPQPALQDVSLTIESGEFVVALGASGCGKTTL----LNLIAgflapSSGEITLDG-- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 ldsltqQQVRPLRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGG 428
Cdd:COG4525    69 ------VPVTGPGADRGVVFQKD--ALLPWLNVLDNVAFGLRLRGVP-KAERRARAEELLALVGLA-DFARRRIWQLSGG 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 429 QRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDL--AVVKALSHQLMVVKQGQVVEQ 506
Cdd:COG4525   139 MRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVeeALFLATRLVVMSPGPGRIVER 218
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 23-250 4.89e-30

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 117.34  E-value: 4.89e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEktirHIRGnrIAMIFQEp 102
Cdd:cd03300    13 FVALDGVSLDIKEGEFFTLLGPSGCGKT----TLLRLIA-GFETPTSGEILLDGKDITNLPP----HKRP--VNTVFQN- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 mTSLNPLHSIEKQINEVLGIhKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03300    81 -YALFPHLTVFENIAFGLRL-KKLPKAEIKERVAEALDLVQLEGYANRK---PSQLSGGQQQRVAIARALVNEPKVLLLD 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQ 250
Cdd:cd03300   156 EPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPA 223
cbiO PRK13650
energy-coupling factor transporter ATPase;
302-536 5.10e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 118.68  E-value: 5.10e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTlglaILRLIG-----SKGGIRFEGkqlDSLTQQQVRPLRREMQVVFQDPfgsls 376
Cdd:PRK13650   23 LNDVSFHVKQGEWLSIIGHNGSGKST----TVRLIDglleaESGQIIIDG---DLLTEENVWDIRHKIGMVFQNP----- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prmcVSQIVG-------------EGLRIHKMGTEAEQeqaiiaALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKP 443
Cdd:PRK13650   91 ----DNQFVGatveddvafglenKGIPHEEMKERVNE------ALELVGMQ-DFKEREPARLSGGQKQRVAIAGAVAMRP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 444 ALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAApqhpyTQQ 523
Cdd:PRK13650  160 KIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFSR-----GND 233

                         250
                  ....*....|...
gi 1834229548 524 LLEAAFLVPATAQ 536
Cdd:PRK13650  234 LLQLGLDIPFTTS 246
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
275-529 5.62e-30

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 117.91  E-value: 5.62e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPikkgllKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-----GSKGGIRFEGKQL 349
Cdd:COG4559     1 MLEAENLSVRLG------GRTL-----LDDVSLTLRPGELTAIIGPNGAGKSTL----LKLLtgeltPSSGEVRLNGRPL 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQQQvrpLRREMQVVFQD-----PFGslsprmcVSQIVGEGLRIHkmGTEAEQEQAII-AALKEVGLDPeTRHRYPH 423
Cdd:COG4559    66 AAWSPWE---LARRRAVLPQHsslafPFT-------VEEVVALGRAPH--GSSAAQDRQIVrEALALVGLAH-LAGRSYQ 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 424 EFSGGQRQRIAIARALV-------LKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLM 496
Cdd:COG4559   133 TLSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARR-GGGVVAVLHDLNLAAQYADRIL 211

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1834229548 497 VVKQGQVVEQGDAQSIFaapqhpyTQQLLEAAF 529
Cdd:COG4559   212 LLHQGRLVAQGTPEEVL-------TDELLERVY 237
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 299-502 5.76e-30

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 117.15  E-value: 5.76e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-----GSKGGIRF--EGKQLD--SLTQQQVRPLRR-EMQVVF 368
Cdd:COG4778    24 LPVLDGVSFSVAAGECVALTGPSGAGKSTL----LKCIygnylPDSGSILVrhDGGWVDlaQASPREILALRRrTIGYVS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QdpFGSLSPRMCVSQIVGEGLRihKMGTEAEQEQAIIAA-LKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALIL 447
Cdd:COG4778   100 Q--FLRVIPRVSALDVVAEPLL--ERGVDREEARARARElLARLNLPERLWDLPPATFSGGEQQRVNIARGFIADPPLLL 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 448 LDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:COG4778   176 LDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVTPFS 229
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
6-234 6.00e-30

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 117.22  E-value: 6.00e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHsILRLLPYPlarhPSGTIEYSGQNLLNLKEK 85
Cdd:PRK11629    5 LLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLH-LLGGLDTP----TSGDVIFNGQPMSKLSSA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQ--EPMTSLNPLHSIEKQInevlgihkgLIGKV----ATKRTLELLEMVGIpepEKRLKALPHELS 159
Cdd:PRK11629   80 AKAELRNQKLGFIYQfhHLLPDFTALENVAMPL---------LIGKKkpaeINSRALEMLAAVGL---EHRANHRPSELS 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIaHRVCVMQRG 234
Cdd:PRK11629  148 GGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRM-SRQLEMRDG 221
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 308-507 1.28e-29

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 115.67  E-value: 1.28e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 308 SLPQGQTLGIVGESGSGKSTLglaiLRLIGSkggirFEGKQLDSLTQQQV-----RPLRREMQVVFQDpfGSLSPRMCVS 382
Cdd:cd03298    20 TFAQGEITAIVGPSGSGKSTL----LNLIAG-----FETPQSGRVLINGVdvtaaPPADRPVSMLFQE--NNLFAHLTVE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 383 QIVGEGlRIHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQ 462
Cdd:cd03298    89 QNVGLG-LSPGLKLTAEDRQAIEVALARVGLA-GLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAE 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 463 VVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03298   167 MLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 301-513 1.39e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 117.40  E-value: 1.39e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLG---LAILRliGSKGGIRFEGKQLDSLTqqqVRPLRREMQVVFQDPfgslsp 377
Cdd:PRK13632   24 ALKNVSFEINEGEYVAILGHNGSGKSTISkilTGLLK--PQSGEIKIDGITISKEN---LKEIRKKIGIIFQNP------ 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 rmcVSQIVGE--------GLRiHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:PRK13632   93 ---DNQFIGAtveddiafGLE-NKKVPPKKMKDIIDDLAKKVGME-DYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFD 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDL-AVVKAlsHQLMVVKQGQVVEQGDAQSIF 513
Cdd:PRK13632  168 ESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMdEAILA--DKVIVFSEGKLIAQGKPKEIL 230
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 263-523 2.39e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 116.73  E-value: 2.39e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 263 SGTPATNVVGPPMLTVEdlkvwfpIKKGLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGI 342
Cdd:PRK14271   10 SGAADVDAAAPAMAAVN-------LTLGFAGKTV-----LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 343 RFEGKQL----DSLTQQQVRPLRREMQVVFQDPfgslSP-RMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPET 417
Cdd:PRK14271   78 RYSGDVLlggrSIFNYRDVLEFRRRVGMLFQRP----NPfPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAV 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 418 RHRY---PHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKynLTYLFISHDLAVVKALSHQ 494
Cdd:PRK14271  154 KDRLsdsPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDR 231

                         250       260
                  ....*....|....*....|....*....
gi 1834229548 495 LMVVKQGQVVEQGDAQSIFAAPQHPYTQQ 523
Cdd:PRK14271  232 AALFFDGRLVEEGPTEQLFSSPKHAETAR 260
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 7-245 2.97e-29

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 122.25  E-value: 2.97e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYSGQNLLN 81
Cdd:COG2274   474 IELEN--VSFRYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKS----TLLKLLlglyePT------SGRILIDGIDLRQ 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRhirgNRIAMIFQEPM----------TSLNPLHSIEkQINEVLgihkgligkvatkrtlellEMVGIpepEKRL 151
Cdd:COG2274   542 IDPASLR----RQIGVVLQDVFlfsgtireniTLGDPDATDE-EIIEAA-------------------RLAGL---HDFI 594

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 152 KALPH-----------ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQlkILELLKELQARLGMALLLISHDLNL 220
Cdd:COG2274   595 EALPMgydtvvgeggsNLSGGQRQRLAIARALLRNPRILILDEATSALDAETE--AIILENLRRLLKGRTVIIIAHRLST 672

                         250       260
                  ....*....|....*....|....*
gi 1834229548 221 VkRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:COG2274   673 I-RLADRIIVLDKGRIVEDGTHEEL 696
cbiO PRK13646
energy-coupling factor transporter ATPase;
300-514 3.19e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 116.80  E-value: 3.19e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQ-QQVRPLRREMQVVFQDPFGSLSP 377
Cdd:PRK13646   21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKpTTGTVTVDDITITHKTKdKYIRPVRKRIGMVFQFPESQLFE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGeGLRIHKMGTEAEQEQAIiAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:PRK13646  101 DTVEREIIF-GPKNFKMNLDEVKNYAH-RLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDP 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 458 TVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:PRK13646  179 QSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK 235
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 274-468 3.25e-29

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 114.50  E-value: 3.25e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFpikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQ 348
Cdd:COG4133     1 MMLEAENLSCRR-----------GERLLFSGLSFTLAAGEALALTGPNGSGKTTL----LRILAgllppSAGEVLWNGEP 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDsltqQQVRPLRREMQVVFQDP--FGSLSPRmcvsqivgEGLRIH-KMGTEAEQEQAIIAALKEVGLDPEtRHRYPHEF 425
Cdd:COG4133    66 IR----DAREDYRRRLAYLGHADglKPELTVR--------ENLRFWaALYGLRADREAIDEALEAVGLAGL-ADLPVRQL 132

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1834229548 426 SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLR 468
Cdd:COG4133   133 SAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIA 175
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
2-247 3.46e-29

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 116.65  E-value: 3.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLavEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLln 81
Cdd:PRK13635    1 MKEEIIRVEHI--SFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLL-----LPEAGTITVGGMVL-- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 lKEKTIRHIRgNRIAMIFQEPMtslnplhsiekqiNEVLGIhkgligkvatkrTLE-----LLEMVGIPEPE--KRLK-A 153
Cdd:PRK13635   72 -SEETVWDVR-RQVGMVFQNPD-------------NQFVGA------------TVQddvafGLENIGVPREEmvERVDqA 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 154 L------------PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLV 221
Cdd:PRK13635  125 LrqvgmedflnrePHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEA 204

                         250       260
                  ....*....|....*....|....*.
gi 1834229548 222 KRiAHRVCVMQRGCIVEQASCEQLFR 247
Cdd:PRK13635  205 AQ-ADRVIVMNKGEILEEGTPEEIFK 229
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 299-514 4.19e-29

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 114.94  E-value: 4.19e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLtqqQVRPLRREMQVVFQDP---FGS 374
Cdd:cd03249    16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGeILLDGVDIRDL---NLRWLRSQIGLVSQEPvlfDGT 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 lsprmcvsqiVGEGLRIHKmgTEAEQEQaIIAALKEVGLdpetrhrypHEF-------------------SGGQRQRIAI 435
Cdd:cd03249    93 ----------IAENIRYGK--PDATDEE-VEEAAKKANI---------HDFimslpdgydtlvgergsqlSGGQKQRIAI 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 436 ARALVLKPALILLDEPTSALDRTVQRQVVELLRslQSKYNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:cd03249   151 ARALLRNPKILLLDEATSALDAESEKLVQEALD--RAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDELMA 226
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
287-525 4.89e-29

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 118.98  E-value: 4.89e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 287 IKKGLLKKTV----DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRPLR 361
Cdd:PRK10070   25 IEQGLSKEQIlektGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEpTRGQVLIDGVDIAKISDAELREVR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 362 RE-MQVVFQDpfGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALV 440
Cdd:PRK10070  105 RKkIAMVFQS--FALMPHMTVLDNTAFGMELAGINAEERREKAL-DALRQVGLE-NYAHSYPDELSGGMRQRVGLARALA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 441 LKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPY 520
Cdd:PRK10070  181 INPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDY 260


                  ....*
gi 1834229548 521 TQQLL 525
Cdd:PRK10070  261 VRTFF 265
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 297-523 5.17e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 115.52  E-value: 5.17e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQL---DSLTQQQVR--PLRREMQVVFQDP 371
Cdd:PRK14258   18 DTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVRVEGRVEffnQNIYERRVNlnRLRRQVSMVHPKP 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 fgSLSPrMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETR---HRYPHEFSGGQRQRIAIARALVLKPALILL 448
Cdd:PRK14258   98 --NLFP-MSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDEIKhkiHKSALDLSGGQQQRLCIARALAVKPKVLLM 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 449 DEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQ-----GQVVEQGDAQSIFAAPQHPYTQQ 523
Cdd:PRK14258  175 DEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIFNSPHDSRTRE 254
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
301-513 5.95e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 115.96  E-value: 5.95e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAI-LRLIGSKGGIRFEGkqLDSLTQQQVRPLRREMQVVFQDPFGSLsprm 379
Cdd:PRK13633   25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMnALLIPSEGKVYVDG--LDTSDEENLWDIRNKAGMVFQNPDNQI---- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 cVSQIVGEGLRI--HKMGTEAEQ-EQAIIAALKEVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PRK13633   99 -VATIVEEDVAFgpENLGIPPEEiRERVDESLKKVGMYEYRRHA-PHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLD 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 457 RTVQRQVVELLRSLQSKYNLTYLFISHDL-AVVKAlsHQLMVVKQGQVVEQGDAQSIF 513
Cdd:PRK13633  177 PSGRREVVNTIKELNKKYGITIILITHYMeEAVEA--DRIIVMDSGKVVMEGTPKEIF 232
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 8-234 7.13e-29

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 111.95  E-value: 7.13e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKTI 87
Cdd:cd00267     1 EIENLSFRY--GGR--TALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPT-----SGEILIDGKDIAKLPLEEL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  88 RhirgNRIAMIFQepmtslnplhsiekqinevlgihkgligkvatkrtlellemvgipepekrlkalpheLSGGQRQRVM 167
Cdd:cd00267    72 R----RRIGYVPQ---------------------------------------------------------LSGGQRQRVA 90

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 168 IAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd00267    91 LARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDG 156
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
23-250 7.51e-29

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 114.34  E-value: 7.51e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPypLARHP-SGTIEYSGQNL---LNLKEKTIRHIRGNrIAMI 98
Cdd:COG4161    15 HQALFDINLECPSGETLVLLGPSGAGKS----SLLRVLN--LLETPdSGQLNIAGHQFdfsQKPSEKAIRLLRQK-VGMV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  99 FQE----P-MTSLNPLhsIEKQINeVLGIHKgligKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALA 173
Cdd:COG4161    88 FQQynlwPhLTVMENL--IEAPCK-VLGLSK----EQAREKAMKLLARLRL---TDKADRFPLHLSGGQQQRVAIARALM 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 174 NEPELLIADEPTTALD--VTVQLKILELLKelqARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEqLFRAPQ 250
Cdd:COG4161   158 MEPQVLLFDEPTAALDpeITAQVVEIIREL---SQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDAS-HFTQPQ 232
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
 303-516 9.24e-29

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 120.83  E-value: 9.24e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLglaiLR-LIG----SKGGIRFEGKQLDSLTQQQVRplrREMQVVFQDpfGSLSP 377
Cdd:TIGR03797 470 DDVSLQIEPGEFVAIVGPSGSGKSTL----LRlLLGfetpESGSVFYDGQDLAGLDVQAVR---RQLGVVLQN--GRLMS 540

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGeglrihkmGTEAEQEQAIiAALKEVGLDPETR------HRYPHE----FSGGQRQRIAIARALVLKPALIL 447
Cdd:TIGR03797 541 GSIFENIAG--------GAPLTLDEAW-EAARMAGLAEDIRampmgmHTVISEgggtLSGGQRQRLLIARALVRKPRILL 611

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 448 LDEPTSALDRTVQRQVVELLRSLqskyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:TIGR03797 612 FDEATSALDNRTQAIVSESLERL----KVTRIVIAHRLSTIRN-ADRIYVLDAGRVVQQGTYDELMARE 675
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 297-514 1.39e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 114.94  E-value: 1.39e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGL---AILRliGSKGGIRFEGKQLDsLTQQQVRPLRREMQVVFQDPFG 373
Cdd:PRK13636   17 DGTHALKGININIKKGEVTAILGGNGAGKSTLFQnlnGILK--PSSGRILFDGKPID-YSRKGLMKLRESVGMVFQDPDN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SLSpRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:PRK13636   94 QLF-SASVYQDVSFGAVNLKL-PEDEVRKRVDNALKRTGIEH-LKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTA 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 454 ALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:PRK13636  171 GLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFA 231
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 302-510 1.46e-28

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 112.58  E-value: 1.46e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAIL----RLIGSKGGIRFEGKQLDSLTqqqvrPLRREMQVVFQDPFgsLSP 377
Cdd:COG4136    17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAgtlsPAFSASGEVLLNGRRLTALP-----AEQRRIGILFQDDL--LFP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEGL--RIHKmgteAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:COG4136    90 HLSVGENLAFALppTIGR----AQRRARVEQALEEAGLA-GFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKAlshqlmvvkQGQVVEQGDAQ 510
Cdd:COG4136   165 DAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPA---------AGRVLDLGNWQ 210
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 29-250 1.61e-28

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 113.57  E-value: 1.61e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPlarhPSGTIEYSGQNL---LNLKEKTIRHIRGNrIAMIFQE---- 101
Cdd:PRK11124   21 ITLDCPQGETLVLLGPSGAGKS-SLLRVLNLLEMP----RSGTLNIAGNHFdfsKTPSDKAIRELRRN-VGMVFQQynlw 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 P-MTSLNPLhsIEKQINeVLGIHKgligKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLI 180
Cdd:PRK11124   95 PhLTVQQNL--IEAPCR-VLGLSK----DQALARAEKLLERLRLKPYADRF---PLHLSGGQQQRVAIARALMMEPQVLL 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 181 ADEPTTALD--VTVQLKILELLKelqARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ--ASCeqlFRAPQ 250
Cdd:PRK11124  165 FDEPTAALDpeITAQIVSIIREL---AETGITQVIVTHEVEVARKTASRVVYMENGHIVEQgdASC---FTQPQ 232
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 292-523 2.63e-28

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 113.08  E-value: 2.63e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQL---DSLTQQQVRPLRREMQVVF 368
Cdd:PRK14247    9 LKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYPEARVSGEVYldgQDIFKMDVIELRRRVQMVF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDPfgSLSPRMCVSQIVGEGLRIHKM-GTEAEQEQAIIAALKEVGLDPETRHRY---PHEFSGGQRQRIAIARALVLKPA 444
Cdd:PRK14247   89 QIP--NPIPNLSIFENVALGLKLNRLvKSKKELQERVRWALEKAQLWDEVKDRLdapAGKLSGGQQQRLCIARALAFQPE 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 445 LILLDEPTSALDRTVQRQVVELLrsLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQ 523
Cdd:PRK14247  167 VLLADEPTANLDPENTAKIESLF--LELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHELTEK 243
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 24-245 3.46e-28

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 112.08  E-value: 3.46e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLnlkeKTIRHIRgNRIAMIFQEP 102
Cdd:cd03265    14 EAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLK------PtSGRATVAGHDVV----REPREVR-RRIGIVFQDL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 mtslnplhSIEKQIN--EVLGIHK---GLIGKVATKRTLELLEMVGIPEPEKRLKAlphELSGGQRQRVMIAMALANEPE 177
Cdd:cd03265    83 --------SVDDELTgwENLYIHArlyGVPGAERRERIDELLDFVGLLEAADRLVK---TYSGGMRRRLEIARSLVHRPE 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 178 LLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:cd03265   152 VLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 6-503 6.00e-28

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 117.07  E-value: 6.00e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarHPSGTIEYSGQNLLNLKeK 85
Cdd:PRK15439   11 LLCARSISKQY----SGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVP-----PDSGTLEIGGNPCARLT-P 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGnrIAMIFQEPMtsLNPLHSIEKQIneVLGIHKGligKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQR 165
Cdd:PRK15439   81 AKAHQLG--IYLVPQEPL--LFPNLSVKENI--LFGLPKR---QASMQKMKQLLAALGC---QLDLDSSAGSLEVADRQI 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQArLGMALLLISHDLNLVKRIAHRVCVMQRGCIV-----EQA 240
Cdd:PRK15439  149 VEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLA-QGVGIVFISHKLPEIRQLADRISVMRDGTIAlsgktADL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 241 SCEQLFRApQHPYTREL-------LAAEPSGTPATNVVGPPMLTVEDLKvwfpiKKGLLKktvdyvkavdgINFSLPQGQ 313
Cdd:PRK15439  228 STDDIIQA-ITPAAREKslsasqkLWLELPGNRRQQAAGAPVLTVEDLT-----GEGFRN-----------ISLEVRAGE 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 314 TLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSL-TQQQVR------PLRREMQVVFQDpfGSLSPRMCvsqiv 385
Cdd:PRK15439  291 ILGLAGVVGAGRTELAETLYGLRPARGGrIMLNGKEINALsTAQRLArglvylPEDRQSSGLYLD--APLAWNVC----- 363

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 386 geGLRIHKMG--TEAEQEQAII----AAL--KEVGLDPETRhryphEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:PRK15439  364 --ALTHNRRGfwIKPARENAVLeryrRALniKFNHAEQAAR-----TLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDV 436

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 1834229548 458 TVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:PRK15439  437 SARNDIYQLIRSI-AAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 299-507 6.17e-28

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 111.14  E-value: 6.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRL-IGSKGGIRFEG---KQLDsltqqqVRPLRREMQVVFQDP--- 371
Cdd:cd03245    17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLyKPTSGSVLLDGtdiRQLD------PADLRRNIGYVPQDVtlf 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 FGSLSPRMCvsqivgeglrihkMGTEAEQEQAIIAALKEVGLDPETRhRYPHEF-----------SGGQRQRIAIARALV 440
Cdd:cd03245    91 YGTLRDNIT-------------LGAPLADDERILRAAELAGVTDFVN-KHPNGLdlqigergrglSGGQRQAVALARALL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 441 LKPALILLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQG 507
Cdd:cd03245   157 NDPPILLLDEPTSAMDMNSEERLKERLRQLLG--DKTLIIITHRPSLL-DLVDRIIVMDSGRIVADG 220
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
7-260 6.56e-28

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 112.20  E-value: 6.56e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILR---LLPYPlarhPSGTIEYSGQnLLNLK 83
Cdd:COG4598     9 LEVRDLHKSF--GD--LEVLKGVSLTARKGDVISIIGSSGSGKS----TFLRcinLLETP----DSGEIRVGGE-EIRLK 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 -----------EKTIRHIRGnRIAMIFQE-----PMTSLN-----PLHsiekqineVLGIHKgligKVATKRTLELLEMV 142
Cdd:COG4598    76 pdrdgelvpadRRQLQRIRT-RLGMVFQSfnlwsHMTVLEnvieaPVH--------VLGRPK----AEAIERAEALLAKV 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 143 GIPEpekRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALD-------VTVQLKIlellkelqARLGMALLLIS 215
Cdd:COG4598   143 GLAD---KRDAYPAHLSGGQQQRAAIARALAMEPEVMLFDEPTSALDpelvgevLKVMRDL--------AEEGRTMLVVT 211

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 216 HDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELLAA 260
Cdd:COG4598   212 HEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNPKSERLRQFLSS 256
cbiO PRK13642
energy-coupling factor transporter ATPase;
299-535 7.04e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 112.88  E-value: 7.04e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGS-KGGIRFEGKQLdslTQQQVRPLRREMQVVFQDPFGSLSP 377
Cdd:PRK13642   20 VNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEfEGKVKIDGELL---TAENVWNLRRKIGMVFQNPDNQFVG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 rMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHryPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:PRK13642   97 -ATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTRE--PARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDP 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 458 TVQRQVVELLRSLQSKYNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAApqhpyTQQLLEAAFLVPATA 535
Cdd:PRK13642  174 TGRQEIMRVIHEIKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEIIKEAAPSELFAT-----SEDMVEIGLDVPFSS 245
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 6-245 7.96e-28

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 111.49  E-value: 7.96e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLpYPLARHPSGTIEYSGQNLLNLKEK 85
Cdd:COG4555     1 MIEVENLSKKY--GKV--PALKDVSFTAKDGEITGLLGPNGAGKTTL----LRML-AGLLKPDSGSILIDGEDVRKEPRE 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIrgnriAMIFQEpmtslNPLH---SIEKQINEVLGIHkGLIGKVATKRTLELLEMVGIPEPEKRLKalpHELSGGQ 162
Cdd:COG4555    72 ARRQI-----GVLPDE-----RGLYdrlTVRENIRYFAELY-GLFDEELKKRIEELIELLGLEEFLDRRV---GELSTGM 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 163 RQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASC 242
Cdd:COG4555   138 KKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSL 216


                  ...
gi 1834229548 243 EQL 245
Cdd:COG4555   217 DEL 219
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 29-234 8.17e-28

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 110.85  E-value: 8.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKrGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEpmTSLNP 108
Cdd:cd03297    17 IDFDLN-EEVTGIFGASGAGKS----TLLRCIA-GLEKPDGGTIVLNGTVLFDSRKKINLPPQQRKIGLVFQQ--YALFP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 LHSIEKQINEVLgihKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTAL 188
Cdd:cd03297    89 HLNVRENLAFGL---KRKRNREDRISVDELLDLLGL---DHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1834229548 189 DVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd03297   163 DRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDG 208
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 297-507 1.16e-27

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 116.74  E-value: 1.16e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTqqqVRPLRREMQVVFQDPfgsl 375
Cdd:TIGR02203 343 RDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEpDSGQILLDGHDLADYT---LASLRRQVALVSQDV---- 415

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 sprMCVSQIVGEGLRIHKMGT--EAEQEQAIIAA-LKEV------GLDPETRHRyPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:TIGR02203 416 ---VLFNDTIANNIAYGRTEQadRAEIERALAAAyAQDFvdklplGLDTPIGEN-GVLLSGGQRQRLAIARALLKDAPIL 491

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:TIGR02203 492 ILDEATSALDNESERLVQAALERLMQ--GRTTLVIAHRLSTIEK-ADRIVVMDDGRIVERG 549
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
292-516 2.27e-27

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 113.25  E-value: 2.27e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQqqvrplrREMQV 366
Cdd:PRK10851    8 IKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL----LRIIAglehqTSGHIRFHGTDVSRLHA-------RDRKV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 --VFQDPfgSLSPRMCVSQIVGEGLRI---HKMGTEAEQEQAIIAALKEVGLdPETRHRYPHEFSGGQRQRIAIARALVL 441
Cdd:PRK10851   77 gfVFQHY--ALFRHMTVFDNIAFGLTVlprRERPNAAAIKAKVTQLLEMVQL-AHLADRYPAQLSGGQKQRVALARALAV 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 442 KPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:PRK10851  154 EPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREP 228
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
292-522 2.37e-27

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 113.39  E-value: 2.37e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLdsltqQQVRPLRREMQV 366
Cdd:PRK11607   25 LTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTL----LRMLAgfeqpTAGQIMLDGVDL-----SHVPPYQRPINM 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:PRK11607   96 MFQSY--ALFPHMTVEQNIAFGLKQDKL-PKAEIASRVNEMLGLVHMQ-EFAKRKPHQLSGGQRQRVALARSLAKRPKLL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 447 LLDEPTSALDRTV----QRQVVELLRslqsKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFaapQHPYTQ 522
Cdd:PRK11607  172 LLDEPMGALDKKLrdrmQLEVVDILE----RVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIY---EHPTTR 244
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 24-228 2.60e-27

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 109.24  E-value: 2.60e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPlarhPSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEpm 103
Cdd:TIGR03608  12 VILDDLNLTIEKGKMYAIIGESGSGKS-TLLNIIGLLEKF----DSGQVYLNGQETPPLNSKKASKFRREKLGYLFQN-- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 TSLNPLHSIEKQINEVLgIHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADE 183
Cdd:TIGR03608  85 FALIENETVEENLDLGL-KYKKLSKKEKREKKKEALEKVGL---NLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 184 PTTALDvTVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRV 228
Cdd:TIGR03608 161 PTGSLD-PKNRDEVLDLLLELNDEGKTIIIVTHDPEVAKQ-ADRV 203
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 278-536 2.68e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 110.98  E-value: 2.68e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 278 VEDLKVWFPikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaILRLIG----SKGGIRFEGKQLDSLT 353
Cdd:PRK13647    7 VEDLHFRYK----------DGTKALKGLSLSIPEGSKTALLGPNGAGKSTL---LLHLNGiylpQRGRVKVMGREVNAEN 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQVRplrREMQVVFQDPFGSLSPrMCVSQIVGEGLRihKMG-TEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQR 432
Cdd:PRK13647   74 EKWVR---SKVGLVFQDPDDQVFS-STVWDDVAFGPV--NMGlDKDEVERRVEEALKAVRMW-DFRDKPPYHLSYGQKKR 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 433 IAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDaQSI 512
Cdd:PRK13647  147 VAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRL-HNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGD-KSL 224

                         250       260
                  ....*....|....*....|....*
gi 1834229548 513 FAAPqhpytqQLLEAAFL-VPATAQ 536
Cdd:PRK13647  225 LTDE------DIVEQAGLrLPLVAQ 243
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
292-506 2.98e-27

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 112.63  E-value: 2.98e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVD-YVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDsltqqQVRPLRREMQ 365
Cdd:PRK11650    9 VRKSYDgKTQVIKGIDLDVADGEFIVLVGPSGCGKSTL----LRMVAgleriTSGEIWIGGRVVN-----ELEPADRDIA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 366 VVFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPAL 445
Cdd:PRK11650   80 MVFQNY--ALYPHMSVRENMAYGLKIRGMP-KAEIEERVAEAARILELEP-LLDRKPRELSGGQRQRVAMGRAIVREPAV 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 446 ILLDEPTSALDRTVQRQV-VElLRSLQSKYNLTYLFISHDLavVKA--LSHQLMVVKQGqVVEQ 506
Cdd:PRK11650  156 FLFDEPLSNLDAKLRVQMrLE-IQRLHRRLKTTSLYVTHDQ--VEAmtLADRVVVMNGG-VAEQ 215
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 299-516 3.07e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 111.05  E-value: 3.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQLdslTQQQVRPLRREMQVVFQDPFG 373
Cdd:PRK13652   17 KEALNNINFIAPRNSRIAVIGPNGAGKSTLfrhfnGI----LKPTSGSVLIRGEPI---TKENIREVRKFVGLVFQNPDD 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SL-SPrmCVSQIVGEGLRihKMGTEAEQ-EQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:PRK13652   90 QIfSP--TVEQDIAFGPI--NLGLDEETvAHRVSSALHMLGLE-ELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEP 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 452 TSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:PRK13652  165 TAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 306-508 3.14e-27

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 109.18  E-value: 3.14e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 306 NFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTqqqvrPLRREMQVVFQDpfGSLSPRMC 380
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTL----LNLIAgfiepASGSIKVNDQSHTGLA-----PYQRPVSMLFQE--NNLFAHLT 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRiHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQ 460
Cdd:TIGR01277  87 VRQNIGLGLH-PGLKLNAEQQEKVVDAAQQVGIA-DYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLR 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1834229548 461 RQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGD 508
Cdd:TIGR01277 165 EEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSD 212
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 301-512 4.47e-27

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 109.06  E-value: 4.47e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQVrpLRREMQVVFQDP--FGSLSp 377
Cdd:cd03224    15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGsIRFDGRDITGLPPHER--ARAGIGYVPEGRriFPELT- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 rmcvsqiVGEGLRihkMGTEAEQEQAIIAALKEV-GLDP---ETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:cd03224    92 -------VEENLL---LGAYARRRAKRKARLERVyELFPrlkERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSE 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 454 ALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:cd03224   162 GLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 7-237 4.55e-27

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 109.45  E-value: 4.55e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLKEk 85
Cdd:cd03219     1 LEVRGLTKRF--GG--LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLR------PtSGSVLFDGEDITGLPP- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 tirHIRGNR-IAMIFQEP-----MTSLN----PLHSIEKQINEVLGIHKGLigKVATKRTLELLEMVGIPEpekRLKALP 155
Cdd:cd03219    70 ---HEIARLgIGRTFQIPrlfpeLTVLEnvmvAAQARTGSGLLLARARREE--REARERAEELLERVGLAD---LADRPA 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTvQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGC 235
Cdd:cd03219   142 GELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPE-ETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGR 220


                  ..
gi 1834229548 236 IV 237
Cdd:cd03219   221 VI 222
cbiO PRK13640
energy-coupling factor transporter ATPase;
301-517 5.24e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 110.27  E-value: 5.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTlglaILRLIG--------SKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDP- 371
Cdd:PRK13640   22 ALNDISFSIPRGSWTALIGHNGSGKST----ISKLINglllpddnPNSKITVDGI---TLTAKTVWDIREKVGIVFQNPd 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 ---FGSlsprmCVSQIVGEGLRihKMGTEAEQEQAIIA-ALKEVGL----DPEtrhryPHEFSGGQRQRIAIARALVLKP 443
Cdd:PRK13640   95 nqfVGA-----TVGDDVAFGLE--NRAVPRPEMIKIVRdVLADVGMldyiDSE-----PANLSGGQKQRVAIAGILAVEP 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 444 ALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:PRK13640  163 KIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKVE 235
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 25-245 5.66e-27

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 108.68  E-value: 5.66e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplARhpSGTIEYSGQNLLNLK-EKTIRhiRGnrIAMIFQEPM 103
Cdd:cd03224    15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLP---PR--SGSIRFDGRDITGLPpHERAR--AG--IGYVPEGRR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 tsLNPLHSIEKqiNEVLGIHKGLIGKVatKRTLE-LLEMVgiPEPEKRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03224    86 --IFPELTVEE--NLLLGAYARRRAKR--KARLErVYELF--PRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLD 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 183 EPTTALD-VTVQLKILELLKElqARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:cd03224   158 EPSEGLApKIVEEIFEAIREL--RDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 7-245 5.80e-27

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 114.47  E-value: 5.80e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLL-PYplarhpSGTIEYSGQNLLNLKEK 85
Cdd:COG4988   337 IELEDVSFSYPGG---RPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLpPY------SGSILINGVDLSDLDPA 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRhirgNRIAMIFQEPM---TSL-------NPLHSiEKQINEVLgihkgligkvatkRTLELLEMVgipepekrlKALP 155
Cdd:COG4988   408 SWR----RQIAWVPQNPYlfaGTIrenlrlgRPDAS-DEELEAAL-------------EAAGLDEFV---------AALP 460

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 HE-----------LSGGQRQRVMIAMALANEPELLIADEPTTALDvtVQLKILELLKELQARLGMALLLISHDLNLVKRi 224
Cdd:COG4988   461 DGldtplgeggrgLSGGQAQRLALARALLRDAPLLLLDEPTAHLD--AETEAEILQALRRLAKGRTVILITHRLALLAQ- 537

                         250       260
                  ....*....|....*....|.
gi 1834229548 225 AHRVCVMQRGCIVEQASCEQL 245
Cdd:COG4988   538 ADRILVLDDGRIVEQGTHEEL 558
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 7-259 6.12e-27

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 114.48  E-value: 6.12e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKT 86
Cdd:COG4987   334 LELEDVSFRYPGAGRP--VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQ-----SGSITLGGVDLRDLDEDD 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRhirgNRIAMIFQEP----MTSLNPLhsiekqinevlgihkgLIGKV-ATKRTL-ELLEMVGIpepEKRLKALPH---- 156
Cdd:COG4987   407 LR----RRIAVVPQRPhlfdTTLRENL----------------RLARPdATDEELwAALERVGL---GDWLAALPDgldt 463

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 -------ELSGGQRQRVMIAMALANEPELLIADEPTTALD-VTVQLKILELLKELQARlgmALLLISHDLNLVKRiAHRV 228
Cdd:COG4987   464 wlgeggrRLSGGERRRLALARALLRDAPILLLDEPTEGLDaATEQALLADLLEALAGR---TVLLITHRLAGLER-MDRI 539

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1834229548 229 CVMQRGCIVEQASCEQLfrAPQHPYTRELLA 259
Cdd:COG4987   540 LVLEDGRIVEQGTHEEL--LAQNGRYRQLYQ 568
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
6-255 7.68e-27

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 111.85  E-value: 7.68e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEK 85
Cdd:PRK11607   19 LLEIRNLTKSF----DGQHAVDDVSLTIYKGEIFALLGASGCGKS----TLLRMLA-GFEQPTAGQIMLDGVDLSHVPPY 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TirhirgNRIAMIFQEpmTSLNPLHSIEKQIneVLGIHKGLIGKVA-TKRTLELLEMVGIPEPEKRLkalPHELSGGQRQ 164
Cdd:PRK11607   90 Q------RPINMMFQS--YALFPHMTVEQNI--AFGLKQDKLPKAEiASRVNEMLGLVHMQEFAKRK---PHQLSGGQRQ 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQ 244
Cdd:PRK11607  157 RVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEE 236

                         250
                  ....*....|.
gi 1834229548 245 LFrapQHPYTR 255
Cdd:PRK11607  237 IY---EHPTTR 244
cbiO PRK13637
energy-coupling factor transporter ATPase;
29-247 7.99e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 110.14  E-value: 7.99e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLKEKtIRHIRgNRIAMIFQEPMTSLNP 108
Cdd:PRK13637   26 VNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLL-----KPTSGKIIIDGVDITDKKVK-LSDIR-KKVGLVFQYPEYQLFE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 lHSIEKQI-----NevLGIHKGLIgkvaTKRTLELLEMVGIPEPEKRLKAlPHELSGGQRQRVMIAMALANEPELLIADE 183
Cdd:PRK13637   99 -ETIEKDIafgpiN--LGLSEEEI----ENRVKRAMNIVGLDYEDYKDKS-PFELSGGQKRRVAIAGVVAMEPKILILDE 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 184 PTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFR 247
Cdd:PRK13637  171 PTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFK 234
cbiO PRK13641
energy-coupling factor transporter ATPase;
294-517 8.90e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 109.92  E-value: 8.90e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 294 KTVDYV---------KAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQLDSLT-QQQVR 358
Cdd:PRK13641    6 ENVDYIyspgtpmekKGLDNISFELEEGSFVALVGHTGSGKSTLmqhfnAL----LKPSSGTITIAGYHITPETgNKNLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 359 PLRREMQVVFQDPFGSLSPRMCVSQIvgeglrihKMG------TEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQR 432
Cdd:PRK13641   82 KLRKKVSLVFQFPEAQLFENTVLKDV--------EFGpknfgfSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 433 IAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQsKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:PRK13641  154 VAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQ-KAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEI 232


                  ....*
gi 1834229548 513 FAAPQ 517
Cdd:PRK13641  233 FSDKE 237
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 25-261 1.55e-26

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 107.81  E-value: 1.55e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLK-EKtirhirgNRIAMIFQEp 102
Cdd:cd03299    14 KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIK------PdSGKILLNGKDITNLPpEK-------RDISYVPQN- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 mTSLNPLHSIEKQIneVLGIHKGLIGKVAT-KRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIA 181
Cdd:cd03299    80 -YALFPHMTVYKNI--AYGLKKRKVDKKEIeRKVLEIAEMLGI---DHLLNRKPETLSGGEQQRVAIARALVVNPKILLL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 182 DEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELLAAE 261
Cdd:cd03299   154 DEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLGFN 233
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 5-254 2.37e-26

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 107.69  E-value: 2.37e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFVVGErcqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLP-YPLARhPSGTIEYSGQNLLNLK 83
Cdd:PRK14247    2 NKIEIRDLKVSFGQVE----VLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElYPEAR-VSGEVYLDGQDIFKMD 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHirgnRIAMIFQEPmtslNPLHSIEKQINEVLGIHKGLIGKVATK---RTLELLEMVGIPEPEK-RLKALPHELS 159
Cdd:PRK14247   77 VIELRR----RVQMVFQIP----NPIPNLSIFENVALGLKLNRLVKSKKElqeRVRWALEKAQLWDEVKdRLDAPAGKLS 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALDvtVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ 239
Cdd:PRK14247  149 GGQQQRLCIARALAFQPEVLLADEPTANLD--PENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEW 226

                         250
                  ....*....|....*
gi 1834229548 240 ASCEQLFRAPQHPYT 254
Cdd:PRK14247  227 GPTREVFTNPRHELT 241
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 305-523 2.43e-26

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 107.83  E-value: 2.43e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQL---DSLTQQQVRPLRREMQVVFQDPfgSLSPRMC 380
Cdd:PRK14246   29 ITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiYDSKIKVDGKVLyfgKDIFQIDAIKLRKEVGMVFQQP--NPFPHLS 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRY---PHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:PRK14246  107 IYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLnspASQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDI 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 458 TVQRQVVELLRSLqsKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQ 523
Cdd:PRK14246  187 VNSQAIEKLITEL--KNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEK 250
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 7-253 2.63e-26

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 107.43  E-value: 2.63e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIeysgqnLLNLKEKT 86
Cdd:cd03296     3 IEVRNVSKRF--GDF--VALDDVSLDIPSGELVALLGPSGSGKT----TLLRLIA-GLERPDSGTI------LFGGEDAT 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGNRIAMIFQEpmTSLNPLHSIEKQINEVLGIHKGLIGKVAT---KRTLELLEMVGIPEPEKRLkalPHELSGGQR 163
Cdd:cd03296    68 DVPVQERNVGFVFQH--YALFRHMTVFDNVAFGLRVKPRSERPPEAeirAKVHELLKLVQLDWLADRY---PAQLSGGQR 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCE 243
Cdd:cd03296   143 QRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPD 222

                         250
                  ....*....|
gi 1834229548 244 QLFRAPQHPY 253
Cdd:cd03296   223 EVYDHPASPF 232
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
25-258 3.46e-26

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 107.10  E-value: 3.46e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEKtIRHIRgNRIAMIFQE--- 101
Cdd:PRK09493   16 VLHNIDLNIDQGEVVVIIGPSGSGKS----TLLRCIN-KLEEITSGDLIVDGLKVNDPKVD-ERLIR-QEAGMVFQQfyl 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 -P-MTSLNplhsiekqiNEVLG-IH-KGLIGKVATKRTLELLEMVGIPEpekRLKALPHELSGGQRQRVMIAMALANEPE 177
Cdd:PRK09493   89 fPhLTALE---------NVMFGpLRvRGASKEEAEKQARELLAKVGLAE---RAHHYPSELSGGQQQRVAIARALAVKPK 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 178 LLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTREL 257
Cdd:PRK09493  157 LMLFDEPTSALDPELRHEVLKVMQDL-AEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEF 235


                  .
gi 1834229548 258 L 258
Cdd:PRK09493  236 L 236
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 275-517 3.50e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 107.86  E-value: 3.50e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGL---AILRliGSKGGIRFEGKQLDs 351
Cdd:PRK13639    1 ILETRDLKYSYP----------DGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLhfnGILK--PTSGEVLIKGEPIK- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 352 LTQQQVRPLRREMQVVFQDPFGSL-SPRmcVSQIVGEGLRihKMG-TEAEQEQAIIAALKEVGLDPETRhRYPHEFSGGQ 429
Cdd:PRK13639   68 YDKKSLLEVRKTVGIVFQNPDDQLfAPT--VEEDVAFGPL--NLGlSKEEVEKRVKEALKAVGMEGFEN-KPPHHLSGGQ 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:PRK13639  143 KKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDL-NKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTP 221


                  ....*...
gi 1834229548 510 QSIFAAPQ 517
Cdd:PRK13639  222 KEVFSDIE 229
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 24-239 3.55e-26

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 106.21  E-value: 3.55e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhpsgtiEYSGQNLLNLKEKTIRHirGNRIAMIFQEpm 103
Cdd:cd03269    14 TALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIIL-----------PDSGEVLFDGKPLDIAA--RNRIGYLPEE-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 TSLNPLHSIEKQINeVLGIHKGLIGKVATKRTLELLEMVGIPE-PEKRLKalphELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03269    79 RGLYPKMKVIDQLV-YLAQLKGLKKEEARRRIDEWLERLELSEyANKRVE----ELSKGNQQKVQFIAAVIHDPELLILD 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 183 EPTTALDVtVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ 239
Cdd:cd03269   154 EPFSGLDP-VNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLY 209
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
24-505 3.59e-26

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 111.80  E-value: 3.59e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPlarhPSGTIEYSGQNLLNLKEKTIRHirgNRIAMIFQEpM 103
Cdd:PRK09700   19 HALKSVNLTVYPGEIHALLGENGAGKS-TLMKVLSGIHEP----TKGTITINNINYNKLDHKLAAQ---LGIGIIYQE-L 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 TSLNPLhsiekQINEVLGIHKGLIGKV----------ATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALA 173
Cdd:PRK09700   90 SVIDEL-----TVLENLYIGRHLTKKVcgvniidwreMRVRAAMMLLRVGL---KVDLDEKVANLSISHKQMLEIAKTLM 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 174 NEPELLIADEPTTALdvTVQLKILELLKELQARL-GMALLLISHDLNLVKRIAHRVCVMQRGC-----IVEQASCEQLFR 247
Cdd:PRK09700  162 LDAKVIIMDEPTSSL--TNKEVDYLFLIMNQLRKeGTAIVYISHKLAEIRRICDRYTVMKDGSsvcsgMVSDVSNDDIVR 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 248 ApqhPYTRELLAAEPSGTPAT-NVVGPPMLTVEDLkvwfpikkgllkkTVDYVKAVDGINFSLPQGQTLGIVGESGSGKS 326
Cdd:PRK09700  240 L---MVGRELQNRFNAMKENVsNLAHETVFEVRNV-------------TSRDRKKVRDISFSVCRGEILGFAGLVGSGRT 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 327 TLGLAILRLIGSKGG-IRFEGKQ------LDSLTQ--QQVRPLRREMQvvFQDPFgSLSPRMCVSQIVGEGLRIHKMGTE 397
Cdd:PRK09700  304 ELMNCLFGVDKRAGGeIRLNGKDisprspLDAVKKgmAYITESRRDNG--FFPNF-SIAQNMAISRSLKDGGYKGAMGLF 380

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 398 AEQEQAIIA--ALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLqSKYN 475
Cdd:PRK09700  381 HEVDEQRTAenQRELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQL-ADDG 459

                         490       500       510
                  ....*....|....*....|....*....|
gi 1834229548 476 LTYLFISHDLAVVKALSHQLMVVKQGQVVE 505
Cdd:PRK09700  460 KVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
MsbA_rel TIGR02204
ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ...
 299-515 3.71e-26

ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ATP transporter that exports lipid A and to eukaryotic P-glycoproteins.


Pssm-ID: 131259 [Multi-domain]  Cd Length: 576  Bit Score: 112.49  E-value: 3.71e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDP---FGS 374
Cdd:TIGR02204 353 QPALDGLNLTVRPGETVALVGPSGAGKSTLFQLLLRFYDpQSGRILLDGVDLRQLDPAE---LRARMALVPQDPvlfAAS 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 lsprmcvsqiVGEGLRIHKMgtEAEQEQAIIAALKEVGLD-----PETRHRYPHE----FSGGQRQRIAIARALVLKPAL 445
Cdd:TIGR02204 430 ----------VMENIRYGRP--DATDEEVEAAARAAHAHEfisalPEGYDTYLGErgvtLSGGQRQRIAIARAILKDAPI 497

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:TIGR02204 498 LLLDEATSALDAESEQLVQQALETLMK--GRTTLIIAHRLATVLK-ADRIVVMDQGRIVAQGTHAELIAK 564
GguA NF040905
sugar ABC transporter ATP-binding protein;
29-456 4.33e-26

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 111.42  E-value: 4.33e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvTAHSILRllpyplARHPSGTieYSGQNLLNLKEKTIRHIRGNR---IAMIFQEpmTS 105
Cdd:NF040905   20 VNLSVREGEIHALCGENGAGKS-TLMKVLS------GVYPHGS--YEGEILFDGEVCRFKDIRDSEalgIVIIHQE--LA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LNPLHSIEKQI---NEVLgiHKGLIGKVAT-KRTLELLEMVGIPE-PEKRLKalphELSGGQRQRVMIAMALANEPELLI 180
Cdd:NF040905   89 LIPYLSIAENIflgNERA--KRGVIDWNETnRRARELLAKVGLDEsPDTLVT----DIGVGKQQLVEIAKALSKDVKLLI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 181 ADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF----RAPQHPYTRE 256
Cdd:NF040905  163 LDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTIETLDCRADEvtedRIIRGMVGRD 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 257 LLAAEPSGTPAtnvVGPPMLTVEDLKVWFPIKKGLlkktvdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAIL-RL 335
Cdd:NF040905  242 LEDRYPERTPK---IGEVVFEVKNWTVYHPLHPER--------KVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFgRS 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 336 IGSK--GGIRFEGKQLDSLTQQQ--------VRPLRREMQVVFQDP---------FGSLSPRMCVSQI----VGEGLRiH 392
Cdd:NF040905  311 YGRNisGTVFKDGKEVDVSTVSDaidaglayVTEDRKGYGLNLIDDikrnitlanLGKVSRRGVIDENeeikVAEEYR-K 389

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 393 KMGTEAEQEQAIIAALkevgldpetrhryphefSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:NF040905  390 KMNIKTPSVFQKVGNL-----------------SGGNQQKVVLSKWLFTDPDVLILDEPTRGID 436
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
301-536 5.07e-26

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 111.98  E-value: 5.07e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLgLAIL-RLIGSKGG-IRFEGKQLDSLTQQQvrpLRREMQVVFQDPfgslspr 378
Cdd:PRK13657  350 GVEDVSFEAKPGQTVAIVGPTGAGKSTL-INLLqRVFDPQSGrILIDGTDIRTVTRAS---LRRNIAVVFQDA------- 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSQIVGEGLRIHKMG-TEAEQEQAIIAAL-------KEVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:PRK13657  419 GLFNRSIEDNIRVGRPDaTDEEMRAAAERAQahdfierKPDGYDTVVGER-GRQLSGGERQRLAIARALLKDPPILILDE 497

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAAPQHPYtqQLLEAAFL 530
Cdd:PRK13657  498 ATSALDVETEAKVKAALDELMK--GRTTFIIAHRLSTVRN-ADRILVFDNGRVVESGSFDELVARGGRFA--ALLRAQGM 572


                  ....*.
gi 1834229548 531 VPATAQ 536
Cdd:PRK13657  573 LQEDER 578
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 275-507 5.20e-26

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 105.91  E-value: 5.20e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKGllkktvdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGkqL 349
Cdd:cd03266     1 MITADALTKRFRDVKK-------TVQAVDGVSFTVKPGEVTGLLGPNGAGKTTT----LRMLAgllepDAGFATVDG--F 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DslTQQQVRPLRREMQVVFqDPFGsLSPRMCVSQIVGEGLRIHKMgteaeQEQAIIAALKEVG--LD-PETRHRYPHEFS 426
Cdd:cd03266    68 D--VVKEPAEARRRLGFVS-DSTG-LYDRLTARENLEYFAGLYGL-----KGDELTARLEELAdrLGmEELLDRRVGGFS 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 427 GGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQ 506
Cdd:cd03266   139 TGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGRVVYE 217


                  .
gi 1834229548 507 G 507
Cdd:cd03266   218 G 218
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
30-258 6.48e-26

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 105.99  E-value: 6.48e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  30 SFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYSGQNLLNLKEktirhirGNR-IAMIFQEpm 103
Cdd:COG3840    19 DLTIAAGERVAILGPSGAGKS----TLLNLIagflpPD------SGRILWNGQDLTALPP-------AERpVSMLFQE-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 TSLNPLHSIEKQINevLGIHKGL-IGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:COG3840    80 NNLFPHLTVAQNIG--LGLRPGLkLTAEQRAQVEQALERVGLAGLLDRL---PGQLSGGQRQRVALARCLVRKRPILLLD 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELL 258
Cdd:COG3840   155 EPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYL 230
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
303-526 6.78e-26

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 106.77  E-value: 6.78e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDpfGSLSP 377
Cdd:PRK11831   24 DNISLTVPRGKITAIMGPSGIGKTTL----LRLIGgqiapDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQS--GALFT 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETrHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:PRK11831   98 DMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAA-KLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDP 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 458 TVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQhPYTQQLLE 526
Cdd:PRK11831  177 ITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPD-PRVRQFLD 244
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 302-501 7.19e-26

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 105.63  E-value: 7.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDsltqqqvRPLRREMqVVFQDPfgSLS 376
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTL----LNLISglaqpTSGGVILEGKQIT-------EPGPDRM-VVFQNY--SLL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 PRMCVSQIVGEGL-RIHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:TIGR01184  67 PWLTVRENIALAVdRVLPDLSKSERRAIVEEHIALVGLT-EAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGAL 145

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQG 501
Cdd:TIGR01184 146 DALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
25-245 9.47e-26

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 111.02  E-value: 9.47e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLP--YPLArhpSGTIEYSGQNLLNLKEKTIRhirgNRIAMIFQEP 102
Cdd:COG1132   355 VLKDISLTIPPGETVALVGPSGSGKS----TLVNLLLrfYDPT---SGRILIDGVDIRDLTLESLR----RQIGVVPQDT 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 M---TSL-------NPLHSiEKQINEVLgihkgligkvatkRTLELLEMVgipepekrlKALPH-----------ELSGG 161
Cdd:COG1132   424 FlfsGTIrenirygRPDAT-DEEVEEAA-------------KAAQAHEFI---------EALPDgydtvvgergvNLSGG 480

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALDVTVQlkilellKELQARL-----GMALLLISHDLNLVKRiAHRVCVMQRGCI 236
Cdd:COG1132   481 QRQRIAIARALLKDPPILILDEATSALDTETE-------ALIQEALerlmkGRTTIVIAHRLSTIRN-ADRILVLDDGRI 552


                  ....*....
gi 1834229548 237 VEQASCEQL 245
Cdd:COG1132   553 VEQGTHEEL 561
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 1-228 1.02e-25

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 105.25  E-value: 1.02e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRllpyPLARHPSGTIEYSGQNLL 80
Cdd:PRK10584    1 MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKS-TLLAILA----GLDDGSSGEVSLVGQPLH 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRHIRGNRIAMIFQEPM--TSLNPLHSIEkqineVLGIHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHEL 158
Cdd:PRK10584   76 QMDEEARAKLRAKHVGFVFQSFMliPTLNALENVE-----LPALLRGESSRQSRNGAKALLEQLGL---GKRLDHLPAQL 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRV 228
Cdd:PRK10584  148 SGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRL 217
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 297-515 1.10e-25

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 111.50  E-value: 1.10e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEG---KQLDSLTqqqvrpLRREMQVVFQDP- 371
Cdd:TIGR03375 476 QETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQpTEGSVLLDGvdiRQIDPAD------LRRNIGYVPQDPr 549

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 --FGSLSPRMCvsqivgeglrihkMGTEAEQEQAIIAALKEVGLDPETRhRYPHEF-----------SGGQRQRIAIARA 438
Cdd:TIGR03375 550 lfYGTLRDNIA-------------LGAPYADDEEILRAAELAGVTEFVR-RHPDGLdmqigergrslSGGQRQAVALARA 615

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 439 LVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKynLTYLFISHDLAVVKaLSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:TIGR03375 616 LLRDPPILLLDEPTSAMDNRSEERFKDRLKRWLAG--KTLVLVTHRTSLLD-LVDRIIVMDNGRIVADGPKDQVLEA 689
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 302-532 1.11e-25

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 105.55  E-value: 1.11e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG------SKGGIRFEGKQLDSLTqqqVRPLRREMQVVFQDPFGSL 375
Cdd:COG1119    19 LDDISWTVKPGEHWAILGPNGAGKSTL----LSLITgdlpptYGNDVRLFGERRGGED---VWELRKRIGLVSPALQLRF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SPRMCVSQIVGEGL----RIHKMGTEAEQEQAIiAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:COG1119    92 PRDETVLDVVLSGFfdsiGLYREPTDEQRERAR-ELLELLGLA-HLADRPFGTLSQGEQRRVLIARALVKDPELLILDEP 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 452 TSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLA-VVKALSHQLMvVKQGQVVEQGDAQSIFaapqhpyTQQLLEAAFL 530
Cdd:COG1119   170 TAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEeIPPGITHVLL-LKDGRVVAAGPKEEVL-------TSENLSEAFG 241


                  ..
gi 1834229548 531 VP 532
Cdd:COG1119   242 LP 243
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 292-507 1.19e-25

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 104.61  E-value: 1.19e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQldslTQQQVRPLRReMQVVFQD 370
Cdd:cd03268     6 LTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGeITFDGKS----YQKNIEALRR-IGALIEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 371 P--FGSLSPRmcvsqivgEGLRIH---KMGTEAEQEQAiiaaLKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPAL 445
Cdd:cd03268    81 PgfYPNLTAR--------ENLRLLarlLGIRKKRIDEV----LDVVGLK-DSAKKKVKGFSLGMKQRLGIALALLGNPDL 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLQsKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03268   148 LILDEPTNGLDPDGIKELRELILSLR-DQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
type_I_sec_HlyB TIGR01846
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...
 302-507 1.28e-25

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273831 [Multi-domain]  Cd Length: 694  Bit Score: 111.37  E-value: 1.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRL-IGSKGGIRFEGKQLdsltqQQVRP--LRREMQVVFQDPFgslspr 378
Cdd:TIGR01846 473 LSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLyTPQHGQVLVDGVDL-----AIADPawLRRQMGVVLQENV------ 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 mCVSQIVGEGLRIHKMGTEAEQeqaIIAALKEVGLDP---ETRHRYPHE-------FSGGQRQRIAIARALVLKPALILL 448
Cdd:TIGR01846 542 -LFSRSIRDNIALCNPGAPFEH---VIHAAKLAGAHDfisELPQGYNTEvgekganLSGGQRQRIAIARALVGNPRILIF 617

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 449 DEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:TIGR01846 618 DEATSALDYESEALIMRNMREICR--GRTVIIIAHRLSTVRA-CDRIIVLEKGQIAESG 673
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
275-505 1.34e-25

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 105.55  E-value: 1.34e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIKKgllkktvdyvkAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQL 349
Cdd:PRK11248    1 MLQISHLYADYGGKP-----------ALEDINLTLESGELLVVLGPSGCGKTTL----LNLIAgfvpyQHGSITLDGKPV 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQqqvrplrrEMQVVFQDPfgSLSPRMCVSQIVGEGLRIHKMGtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQ 429
Cdd:PRK11248   66 EGPGA--------ERGVVFQNE--GLLPWRNVQDNVAFGLQLAGVE-KMQRLEIAHQMLKKVGLE-GAEKRYIWQLSGGQ 133

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDL--AVVKALSHQLMVVKQGQVVE 505
Cdd:PRK11248  134 RQRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIeeAVFMATELVLLSPGPGRVVE 211
cbiO PRK13650
energy-coupling factor transporter ATPase;
4-246 1.76e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 105.97  E-value: 1.76e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVvGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLlnlK 83
Cdd:PRK13650    2 SNIIEVKNLTFKYK-EDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLL-----EAESGQIIIDGDLL---T 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRgNRIAMIFQEPMtslNPLHSIEKQINEVLGI-HKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQ 162
Cdd:PRK13650   73 EENVWDIR-HKIGMVFQNPD---NQFVGATVEDDVAFGLeNKGIPHEEMKERVNEALELVGMQDFKERE---PARLSGGQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 163 RQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKrIAHRVCVMQRGCIVEQASC 242
Cdd:PRK13650  146 KQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTP 224


                  ....
gi 1834229548 243 EQLF 246
Cdd:PRK13650  225 RELF 228
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
2-259 1.76e-25

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 105.44  E-value: 1.76e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNLLN 81
Cdd:PRK10619    1 MSENKLNVIDLHKRY--GE--HEVLKGVSLQANAGDVISIIGSSGSGKS----TFLRCINF-LEKPSEGSIVVNGQTINL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKE----------KTIRHIRgNRIAMIFQE--PMTSLNPLHSIEKQINEVLGIHKgligKVATKRTLELLEMVGIPEPEK 149
Cdd:PRK10619   72 VRDkdgqlkvadkNQLRLLR-TRLTMVFQHfnLWSHMTVLENVMEAPIQVLGLSK----QEARERAVKYLAKVGIDERAQ 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 150 rlKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVqLKILELLKELQARLGMALLLISHDLNLVKRIAHRVC 229
Cdd:PRK10619  147 --GKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPEL-VGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVI 223

                         250       260       270
                  ....*....|....*....|....*....|
gi 1834229548 230 VMQRGCIVEQASCEQLFRAPQHPYTRELLA 259
Cdd:PRK10619  224 FLHQGKIEEEGAPEQLFGNPQSPRLQQFLK 253
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 287-514 1.88e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 106.32  E-value: 1.88e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 287 IKKGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTL--GLAILrLIGSKGGIRF-------------EGKQLDS 351
Cdd:PRK13651    8 IVKIFNKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFieHLNAL-LLPDTGTIEWifkdeknkkktkeKEKVLEK 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 352 LTQQ--------QVRPLRREMQVVFQDP--------------FGSLSprmcvsqivgeglrihkMGTEAEQEQAIIAA-L 408
Cdd:PRK13651   87 LVIQktrfkkikKIKEIRRRVGVVFQFAeyqlfeqtiekdiiFGPVS-----------------MGVSKEEAKKRAAKyI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 409 KEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVV 488
Cdd:PRK13651  150 ELVGLDESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNV 228

                         250       260
                  ....*....|....*....|....*.
gi 1834229548 489 KALSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:PRK13651  229 LEWTKRTIFFKDGKIIKDGDTYDILS 254
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 300-526 2.34e-25

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 109.91  E-value: 2.34e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQdpfgs 374
Cdd:PRK11160  354 PVLKGLSLQIKAGEKVALLGRTGCGKSTL----LQLLTrawdpQQGEILLNGQPIADYSEAA---LRQAISVVSQ----- 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 lsprmcvsqivgeglRIH----------KMGTEAEQEQAIIAALKEVGLDPETRHRYP---------HEFSGGQRQRIAI 435
Cdd:PRK11160  422 ---------------RVHlfsatlrdnlLLAAPNASDEALIEVLQQVGLEKLLEDDKGlnawlgeggRQLSGGEQRRLGI 486

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 436 ARALvLKPA-LILLDEPTSALDRTVQRQVVELLRSL-QSKynlTYLFISHDLavvKALSH--QLMVVKQGQVVEQGDAQS 511
Cdd:PRK11160  487 ARAL-LHDApLLLLDEPTEGLDAETERQILELLAEHaQNK---TVLMITHRL---TGLEQfdRICVMDNGQIIEQGTHQE 559

                         250
                  ....*....|....*
gi 1834229548 512 IFAapQHPYTQQLLE 526
Cdd:PRK11160  560 LLA--QQGRYYQLKQ 572
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
273-512 2.43e-25

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 109.34  E-value: 2.43e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWFPikkGllkktvdyVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGK 347
Cdd:COG1129     2 EPLLEMRGISKSFG---G--------VKALDGVSLELRPGEVHALLGENGAGKSTL----MKILSgvyqpDSGEILLDGE 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 348 QLDSLTQQQVRplRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHKMGT--EAEQEQAIIAALKEVGL--DPETRHRyph 423
Cdd:COG1129    67 PVRFRSPRDAQ--AAGIAIIHQEL--NLVPNLSVAENIFLGREPRRGGLidWRAMRRRARELLARLGLdiDPDTPVG--- 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 424 EFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:COG1129   140 DLSVAQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLRDGRL 218


                  ....*....
gi 1834229548 504 VEQGDAQSI 512
Cdd:COG1129   219 VGTGPVAEL 227
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 266-513 2.64e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 106.47  E-value: 2.64e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 266 PATNVVGPPMLTVEDLKVWFPikkgllKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKG 340
Cdd:PRK13631   12 VPNPLSDDIILRVKNLYCVFD------EKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLvthfnGL----IKSKYG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 341 GIRFE----------GKQLDSLTQQQVR---PLRREMQVVFQDPFGSLSPRMCVSQIV-GE-GLRIHKmgTEAEQEQAII 405
Cdd:PRK13631   82 TIQVGdiyigdkknnHELITNPYSKKIKnfkELRRRVSMVFQFPEYQLFKDTIEKDIMfGPvALGVKK--SEAKKLAKFY 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 406 aaLKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQsKYNLTYLFISHDL 485
Cdd:PRK13631  160 --LNKMGLDDSYLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAK-ANNKTVFVITHTM 236

                         250       260
                  ....*....|....*....|....*...
gi 1834229548 486 AVVKALSHQLMVVKQGQVVEQGDAQSIF 513
Cdd:PRK13631  237 EHVLEVADEVIVMDKGKILKTGTPYEIF 264
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 300-497 2.65e-25

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 109.30  E-value: 2.65e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQvrpLRREMQVVFQDPFgslspr 378
Cdd:TIGR02857 336 PALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGsIAVNGVPLADADADS---WRDQIAWVPQHPF------ 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 mCVSQIVGEGLRIHKMG-TEAEQEQAIIAA-----LKEVGLDPETR-HRYPHEFSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:TIGR02857 407 -LFAGTIAENIRLARPDaSDAEIREALERAgldefVAALPQGLDTPiGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEP 485

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1834229548 452 TSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKALSHQLMV 497
Cdd:TIGR02857 486 TAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALADRIVVL 529
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 303-503 3.04e-25

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 104.76  E-value: 3.04e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGSkggirfegkqLDSLTQQQVR----PL---RREMQVVFQDpfGSL 375
Cdd:PRK11247   29 NQLDLHIPAGQFVAVVGRSGCGKSTL----LRLLAG----------LETPSAGELLagtaPLaeaREDTRLMFQD--ARL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SPRMCVSQIVGEGLRIHkMGTEAEQeqaiiaALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:PRK11247   93 LPWKKVIDNVGLGLKGQ-WRDAALQ------ALAAVGLA-DRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGAL 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:PRK11247  165 DALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
24-258 3.23e-25

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 106.71  E-value: 3.23e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLkektirHIRGNRIAMIFQ--- 100
Cdd:PRK10851   16 QVLNDISLDIPSGQMVALLGPSGSGKT----TLLRIIA-GLEHQTSGHIRFHGTDVSRL------HARDRKVGFVFQhya 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 101 --EPMTSLNplhSIEKQINeVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPEL 178
Cdd:PRK10851   85 lfRHMTVFD---NIAFGLT-VLPRRERPNAAAIKAKVTQLLEMVQLAHLADRY---PAQLSGGQKQRVALARALAVEPQI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 179 LIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELL 258
Cdd:PRK10851  158 LLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFM 237
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 303-507 3.33e-25

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 109.52  E-value: 3.33e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDP--Fgslsprm 379
Cdd:COG5265   375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDvTSGRILIDGQDIRDVTQAS---LRAAIGIVPQDTvlF------- 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 cvSQIVGEGLRIHKMG-TEAEQEQAI--------IAALKE-----VGldpetrhryphE----FSGGQRQRIAIARALVL 441
Cdd:COG5265   445 --NDTIAYNIAYGRPDaSEEEVEAAAraaqihdfIESLPDgydtrVG-----------ErglkLSGGEKQRVAIARTLLK 511

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 442 KPALILLDEPTSALDRTVQRQVVELLRSLqSKyNLTYLFISHDLA-VVKAlsHQLMVVKQGQVVEQG 507
Cdd:COG5265   512 NPPILIFDEATSALDSRTERAIQAALREV-AR-GRTTLVIAHRLStIVDA--DEILVLEAGRIVERG 574
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 297-507 3.56e-25

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 103.35  E-value: 3.56e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAIL--RLIGSKGGIRFEGKqldSLTQQQVRpLRREMQVVFQDP--F 372
Cdd:cd03263    13 GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTT-LKMLtgELRPTSGTAYINGY---SIRTDRKA-ARQSLGYCPQFDalF 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 GSLSPRmcvsqivgEGLRIHKM--GTEAEQEQAIIAA-LKEVGLDPEtRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:cd03263    88 DELTVR--------EHLRFYARlkGLPKSEIKEEVELlLRVLGLTDK-ANKRARTLSGGMKRKLSLAIALIGGPSVLLLD 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03263   159 EPTSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIG 214
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 301-515 4.69e-25

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 103.72  E-value: 4.69e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRL-IGSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDpfGSLSPRM 379
Cdd:cd03252    17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFyVPENGRVLVDGHDLALADPAW---LRRQVGVVLQE--NVLFNRS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 CVSQIVgeglrihkMGTEAEQEQAIIAALKEVGldpetrhryPHEF-------------------SGGQRQRIAIARALV 440
Cdd:cd03252    92 IRDNIA--------LADPGMSMERVIEAAKLAG---------AHDFiselpegydtivgeqgaglSGGQRQRIAIARALI 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 441 LKPALILLDEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:cd03252   155 HNPRILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAE 226
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
300-510 4.92e-25

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 103.03  E-value: 4.92e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-----GSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDP--- 371
Cdd:PRK10908   16 QALQGVTFHMRPGEMAFLTGHSGAGKSTL----LKLIcgierPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHhll 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 -----FGSLSPRMCVSQIVGEGLRihkmgteaeqeQAIIAALKEVGLDPETRHrYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:PRK10908   92 mdrtvYDNVAIPLIIAGASGDDIR-----------RRVSAALDKVGLLDKAKN-FPIQLSGGEQQRVGIARAVVNKPAVL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQ 510
Cdd:PRK10908  160 LADEPTGNLDDALSEGILRLFEEF-NRVGVTVLMATHDIGLISRRSYRMLTLSDGHLHGGVGGE 222
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 292-507 5.57e-25

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 102.66  E-value: 5.57e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTlGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGkqLDSLTQQQvrPLRREMQV 366
Cdd:cd03264     6 LTKRYGKKRALDGVSLTLGPGMY-GLLGPNGAGKTTL----MRILAtltppSSGTIRIDG--QDVLKQPQ--KLRRRIGY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgSLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03264    77 LPQEF--GVYPNFTVREFLDYIAWLKGI-PSKEVKARVDEVLELVNLG-DRAKKKIGSLSGGMRRRVGIAQALVGDPSIL 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 447 LLDEPTSALDrTVQRQVV-ELLRSLQSkyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03264   153 IVDEPTAGLD-PEERIRFrNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
CP_lyasePhnL TIGR02324
phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ...
 275-499 7.73e-25

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.


Pssm-ID: 131377 [Multi-domain]  Cd Length: 224  Bit Score: 102.85  E-value: 7.73e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPI-KKGLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLGLAILR--LIGS-KGGIRFEGKQLD 350
Cdd:TIGR02324   1 LLEVEDLSKTFTLhQQGGVRLPV-----LKNVSLTVNAGECVALSGPSGAGKSTLLKSLYAnyLPDSgRILVRHEGAWVD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 351 --SLTQQQVRPLRR-EMQVVFQdpFGSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLDPETRHRYPHEFSG 427
Cdd:TIGR02324  76 laQASPREVLEVRRkTIGYVSQ--FLRVIPRVSALEVVAEPLLERGVPREAARARAR-ELLARLNIPERLWHLPPATFSG 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 428 GQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVK 499
Cdd:TIGR02324 153 GEQQRVNIARGFIADYPILLLDEPTASLDAANRQVVVELIAEAKAR-GAALIGIFHDEEVRELVADRVMDVT 223
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 7-245 1.30e-24

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 102.23  E-value: 1.30e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQR-VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLlpY-PLarhpSGTIEYSGQNLLNLke 84
Cdd:cd03249     1 IEFKN--VSFRYPSRPDVpILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERF--YdPT----SGEILLDGVDIRDL-- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 kTIRHIRgNRIAMIFQEPMTSLNplhSIEKQInevlgihkgLIGKvaTKRTLELLEMV-GIPEPEKRLKALPH------- 156
Cdd:cd03249    71 -NLRWLR-SQIGLVSQEPVLFDG---TIAENI---------RYGK--PDATDEEVEEAaKKANIHDFIMSLPDgydtlvg 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 ----ELSGGQRQRVMIAMALANEPELLIADEPTTALDvtVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQ 232
Cdd:cd03249   135 ergsQLSGGQKQRIAIARALLRNPKILLLDEATSALD--AESEKLVQEALDRAMKGRTTIVIAHRLSTIRN-ADLIAVLQ 211

                         250
                  ....*....|...
gi 1834229548 233 RGCIVEQASCEQL 245
Cdd:cd03249   212 NGQVVEQGTHDEL 224
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 7-271 1.57e-24

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 104.77  E-value: 1.57e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLpYPLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:COG3839     4 LELENVSKSY--GG--VEALKDIDLDIEDGEFLVLLGPSGCGKSTL----LRMI-AGLEDPTSGEILIGGRDVTDLPPKD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 irhiRGnrIAMIFQEP-----MTSL-N---PLhsiekqinEVLGIHKGLIgkvaTKRTLELLEMVGIpepEKRLKALPHE 157
Cdd:COG3839    75 ----RN--IAMVFQSYalyphMTVYeNiafPL--------KLRKVPKAEI----DRRVREAAELLGL---EDLLDRKPKQ 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:COG3839   134 LSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQ 213

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1834229548 238 EQASCEQLFRAPQHPYTRELLaaepsGTPATNVV 271
Cdd:COG3839   214 QVGTPEELYDRPANLFVAGFI-----GSPPMNLL 242
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 24-261 1.67e-24

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 103.65  E-value: 1.67e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLlnlKEKTIRHI------RGnriam 97
Cdd:COG4152    15 TAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGIL-----APDSGEVLWDGEPL---DPEDRRRIgylpeeRG----- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  98 ifqepmtsLNPLHSIEKQInEVLGIHKGLIGKVATKRTLELLEMVGIPE-PEKRLKalphELSGGQRQRVMIAMALANEP 176
Cdd:COG4152    82 --------LYPKMKVGEQL-VYLARLKGLSKAEAKRRADEWLERLGLGDrANKKVE----ELSKGNQQKVQLIAALLHDP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 177 ELLIADEPTTALD-VTVQlkILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLfRApQHPYTR 255
Cdd:COG4152   149 ELLILDEPFSGLDpVNVE--LLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI-RR-QFGRNT 224


                  ....*.
gi 1834229548 256 ELLAAE 261
Cdd:COG4152   225 LRLEAD 230
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 292-507 2.32e-24

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 101.29  E-value: 2.32e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTL--GLAILrLIGSKGGIRFEGkqLDSLtqQQVRPLRREMQVVFQ 369
Cdd:cd03265     6 LVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTikMLTTL-LKPTSGRATVAG--HDVV--REPREVRRRIGIVFQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 370 DPfgSLSPRMCVSQIVGEGLRIHKMGTeAEQEQAIIAALKEVGLdPETRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:cd03265    81 DL--SVDDELTGWENLYIHARLYGVPG-AERRERIDELLDFVGL-LEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLD 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03265   157 EPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEG 214
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 6-234 2.97e-24

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 100.97  E-value: 2.97e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFV---VGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQ----N 78
Cdd:COG4778     4 LLEVENLSKTFTlhlQGGKRLPVLDGVSFSVAAGECVALTGPSGAGKS----TLLKCI-YGNYLPDSGSILVRHDggwvD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 LLNLKEKTIRHIRGNRIAMIFQEpmtslnpLHSIEKQ-----INEVLgIHKGLIGKVATKRTLELLEMVGIPEpekRLKA 153
Cdd:COG4778    79 LAQASPREILALRRRTIGYVSQF-------LRVIPRVsaldvVAEPL-LERGVDREEARARARELLARLNLPE---RLWD 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 154 L-PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:COG4778   148 LpPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVT 226


                  ..
gi 1834229548 233 RG 234
Cdd:COG4778   227 PF 228
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 8-237 3.84e-24

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 100.02  E-value: 3.84e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRDLAVEFvvgERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplarhpSGTI-EYSGQNLLNlKEKT 86
Cdd:cd03226     1 RIENISFSY---KKGTEILDDLSLDLYAGEIIALTGKNGAGKT----TLAKIL--------AGLIkESSGSILLN-GKPI 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGNRIAMIFQEPMTSLnplhsIEKQINEVLGIHKGLIGKVATKrTLELLEMVGIPEPEKRLkalPHELSGGQRQRV 166
Cdd:cd03226    65 KAKERRKSIGYVMQDVDYQL-----FTDSVREELLLGLKELDAGNEQ-AETVLKDLDLYALKERH---PLSLSGGQKQRL 135

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 167 MIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:cd03226   136 AIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-247 4.58e-24

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 105.65  E-value: 4.58e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGER-CQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPlarhPSGTIEYS-GQNLLN 81
Cdd:TIGR03269 277 EPIIKVRNVSKRYISVDRgVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLE-P----TSGEVNVRvGDEWVD 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHiRGNR---IAMIFQEpmTSLNPLHSIEKQINEVLGIHkgLIGKVATKRTLELLEMVGIPEPEKR--LKALPH 156
Cdd:TIGR03269 352 MTKPGPDG-RGRAkryIGILHQE--YDLYPHRTVLDNLTEAIGLE--LPDELARMKAVITLKMVGFDEEKAEeiLDKYPD 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCI 236
Cdd:TIGR03269 427 ELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKI 506

                         250
                  ....*....|.
gi 1834229548 237 VEQASCEQLFR 247
Cdd:TIGR03269 507 VKIGDPEEIVE 517
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 299-504 5.91e-24

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 98.27  E-value: 5.91e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAIL--RLIGSKGGIRFEGKQLDSLTQQQVRplRREMQVVFQdpfgsls 376
Cdd:cd03216    13 VKALDGVSLSVRRGEVHALLGENGAGKSTL-MKILsgLYKPDSGEILVDGKEVSFASPRDAR--RAGIAMVYQ------- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prmcvsqivgeglrihkmgteaeqeqaiiaalkevgldpetrhrypheFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:cd03216    83 ------------------------------------------------LSVGERQMVEIARALARNARLLILDEPTAALT 114

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1834229548 457 RTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:cd03216   115 PAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 25-239 8.77e-24

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 99.25  E-value: 8.77e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLPyPLARHPSGTIEYSGQNLLNLKEKTirhiRGnrIAMIFQEpmT 104
Cdd:cd03301    15 ALDDLNLDIADGEFVVLLGPSGCGKTTT----LRMIA-GLEEPTSGRIYIGGRDVTDLPPKD----RD--IAMVFQN--Y 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 SLNPLHSIEKQINEVLGIHKGLIGKVAtKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEP 184
Cdd:cd03301    82 ALYPHMTVYDNIAFGLKLRKVPKDEID-ERVREVAELLQI---EHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEP 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 185 TTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGcIVEQ 239
Cdd:cd03301   158 LSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDG-QIQQ 211
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 256-483 1.06e-23

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 104.89  E-value: 1.06e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 256 ELLAAEPSGTPATNVVGPPMLTVEDLKVWFPikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRL 335
Cdd:COG4178   343 EAADALPEAASRIETSEDGALALEDLTLRTP----------DGRPLLEDLSLSLKPGERLLITGPSGSGKSTL----LRA 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 336 I------GSkGGIRfegkqldsltqqqvRPLRREMQVVFQDPF---GSL-----SPRmcvsqivgeglrihkmGTEAEQE 401
Cdd:COG4178   409 IaglwpyGS-GRIA--------------RPAGARVLFLPQRPYlplGTLreallYPA----------------TAEAFSD 457

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 402 QAIIAALKEVGLDP-----ETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRslQSKYNL 476
Cdd:COG4178   458 AELREALEAVGLGHlaerlDEEADWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLR--EELPGT 535


                  ....*..
gi 1834229548 477 TYLFISH 483
Cdd:COG4178   536 TVISVGH 542
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 273-517 1.12e-23

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 99.67  E-value: 1.12e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWfpikkgllkktvdY--VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQL 349
Cdd:COG0410     1 MPMLEVENLHAG-------------YggIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGsIRFDGEDI 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSL-TQQQVR------PLRREMqvvfqdpFGSLSprmcvsqiVGEGLRihkMGTEAEQEQAIIAA-LKEV-GLDP---ET 417
Cdd:COG0410    68 TGLpPHRIARlgigyvPEGRRI-------FPSLT--------VEENLL---LGAYARRDRAEVRAdLERVyELFPrlkER 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 418 RHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMV 497
Cdd:COG0410   130 RRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYV 208

                         250       260
                  ....*....|....*....|
gi 1834229548 498 VKQGQVVEQGDAQSIFAAPQ 517
Cdd:COG0410   209 LERGRIVLEGTAAELLADPE 228
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
306-512 1.13e-23

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 99.66  E-value: 1.13e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 306 NFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKqldslTQQQVRPLRREMQVVFQDpfGSLSPRMC 380
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTL----LNLIAgfltpASGSLTLNGQ-----DHTTTPPSRRPVSMLFQE--NNLFSHLT 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVG----EGLRIhkmgtEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PRK10771   88 VAQNIGlglnPGLKL-----NAAQREKLHAIARQMGIE-DLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALD 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 457 RTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:PRK10771  162 PALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 304-507 1.15e-23

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 105.19  E-value: 1.15e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKqldSLTQQQVRPLRREMQVVFQDPfgsLSPRMCVS 382
Cdd:TIGR00958 499 GLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGqVLLDGV---PLVQYDHHYLHRQVALVGQEP---VLFSGSVR 572

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 383 QIVGEGLrihkmgTEAEQEQaIIAALKEVGLDP---ETRHRYPHE-------FSGGQRQRIAIARALVLKPALILLDEPT 452
Cdd:TIGR00958 573 ENIAYGL------TDTPDEE-IMAAAKAANAHDfimEFPNGYDTEvgekgsqLSGGQKQRIAIARALVRKPRVLILDEAT 645

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 453 SALDRTVQRqvveLLRSLQSKYNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:TIGR00958 646 SALDAECEQ----LLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMG 695
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 41-258 1.80e-23

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 101.42  E-value: 1.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  41 LVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEktirHIRGnrIAMIFQEpmTSLNPLHSIEKQINEVL 120
Cdd:TIGR01187   1 LLGPSGCGKT----TLLRLLA-GFEQPDSGSIMLDGEDVTNVPP----HLRH--INMVFQS--YALFPHMTVEENVAFGL 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 121 GIhKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELL 200
Cdd:TIGR01187  68 KM-RKVPRAEIKPRVLEALRLVQLEEFADRK---PHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLEL 143

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 201 KELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRELL 258
Cdd:TIGR01187 144 KTIQEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFI 201
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 275-504 3.07e-23

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 99.00  E-value: 3.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPikkgllKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQL 349
Cdd:COG1101     1 MLELKNLSKTFN------PGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTL----LNAIAgslppDSGSILIDGKDV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQQqvrplRREMQV--VFQDPFGSLSPRMCVsqivgE-------------GLRIhkmGTEAEQEQAIIAALKEVGLD 414
Cdd:COG1101    71 TKLPEY-----KRAKYIgrVFQDPMMGTAPSMTI-----EenlalayrrgkrrGLRR---GLTKKRRELFRELLATLGLG 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 415 PETRHRYPHEF-SGGQRQRIAIARALVLKPALILLDEPTSALD-RTVQrQVVELLRSLQSKYNLTYLFISHDLAvvKALS 492
Cdd:COG1101   138 LENRLDTKVGLlSGGQRQALSLLMATLTKPKLLLLDEHTAALDpKTAA-LVLELTEKIVEENNLTTLMVTHNME--QALD 214

                         250
                  ....*....|....
gi 1834229548 493 H--QLMVVKQGQVV 504
Cdd:COG1101   215 YgnRLIMMHEGRII 228
cbiO PRK13644
energy-coupling factor transporter ATPase;
297-516 3.72e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 99.29  E-value: 3.72e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 297 DYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGiRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLs 376
Cdd:PRK13644   13 DGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKG-KVLVSGIDTGDFSKLQGIRKLVGIVFQNPETQF- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prmcVSQIVGEGLrihKMGTE------AEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDE 450
Cdd:PRK13644   91 ----VGRTVEEDL---AFGPEnlclppIEIRKRVDRALAEIGLE-KYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDE 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:PRK13644  163 VTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENVLSDV 226
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
 7-249 3.94e-23

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 103.50  E-value: 3.94e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL---PYPLarhpSGTIEYSGQNLLNLK 83
Cdd:TIGR03797 452 IEVDR--VTFRYRPDGPLILDDVSLQIEPGEFVAIVGPSGSGKS----TLLRLLlgfETPE----SGSVFYDGQDLAGLD 521

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRhirgNRIAMIFQ--EPMTSlnplhSIEKQInevlgihkgLIGKVAT-KRTLELLEMVGIpepEKRLKALP---H- 156
Cdd:TIGR03797 522 VQAVR----RQLGVVLQngRLMSG-----SIFENI---------AGGAPLTlDEAWEAARMAGL---AEDIRAMPmgmHt 580

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 -------ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLkelqARLGMALLLISHDLNLVKRiAHRVC 229
Cdd:TIGR03797 581 visegggTLSGGQRQRLLIARALVRKPRILLFDEATSALDNRTQAIVSESL----ERLKVTRIVIAHRLSTIRN-ADRIY 655

                         250       260
                  ....*....|....*....|
gi 1834229548 230 VMQRGCIVEQASCEQLFRAP 249
Cdd:TIGR03797 656 VLDAGRVVQQGTYDELMARE 675
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 256-485 4.07e-23

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 102.82  E-value: 4.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 256 ELLAAEPSG-TPATNVVGPPMLTVEDLKVWFPikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILR 334
Cdd:TIGR02868 314 AGPVAEGSApAAGAVGLGKPTLELRDLSAGYP----------GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAG 383

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 335 LIGSKGG-IRFEGKQLDSLTQQQVRplrREMQVVFQDP--FGSlsprmcvsqIVGEGLRIhkmGTEAEQEQAIIAALKEV 411
Cdd:TIGR02868 384 LLDPLQGeVTLDGVPVSSLDQDEVR---RRVSVCAQDAhlFDT---------TVRENLRL---ARPDATDEELWAALERV 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 412 GLDPETRhRYPH-----------EFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYnlTYLF 480
Cdd:TIGR02868 449 GLADWLR-ALPDgldtvlgeggaRLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSGR--TVVL 525


                  ....*
gi 1834229548 481 ISHDL 485
Cdd:TIGR02868 526 ITHHL 530
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
26-255 4.19e-23

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 101.65  E-value: 4.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplarHPS-GTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEpmT 104
Cdd:PRK10070   44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLI------EPTrGQVLIDGVDIAKISDAELREVRRKKIAMVFQS--F 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 SLNPLHSIEKqiNEVLGIH-KGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADE 183
Cdd:PRK10070  116 ALMPHMTVLD--NTAFGMElAGINAEERREKALDALRQVGL---ENYAHSYPDELSGGMRQRVGLARALAINPDILLMDE 190

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 184 PTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTR 255
Cdd:PRK10070  191 AFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVR 262
cbiO PRK13646
energy-coupling factor transporter ATPase;
29-247 5.97e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 98.70  E-value: 5.97e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLN-LKEKTIRHIRgNRIAMIFQEPMTSLN 107
Cdd:PRK13646   26 VNTEFEQGKYYAIVGQTGSGKSTLIQNINALL-----KPTTGTVTVDDITITHkTKDKYIRPVR-KRIGMVFQFPESQLF 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 108 PlHSIEKQI-----NEVLGIHKgligkvATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:PRK13646  100 E-DTVEREIifgpkNFKMNLDE------VKNYAHRLLMDLGFSR--DVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLD 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFR 247
Cdd:PRK13646  171 EPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK 235
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
275-514 6.04e-23

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 98.54  E-value: 6.04e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLkvWF-----PIKKGLlkkTVDYVKAVdginfslpqgqTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQ 348
Cdd:PRK13638    1 MLATSDL--WFryqdePVLKGL---NLDFSLSP-----------VTGLVGANGCGKSTLFMNLSGLLrPQKGAVLWQGKP 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDsLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQIvgeGLRIHKMGT-EAEQEQAIIAALKEVGLDpETRHRYPHEFSG 427
Cdd:PRK13638   65 LD-YSKRGLLALRQQVATVFQDPEQQIFYTDIDSDI---AFSLRNLGVpEAEITRRVDEALTLVDAQ-HFRHQPIQCLSH 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 428 GQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTyLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:PRK13638  140 GQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGNHV-IISSHDIDLIYEISDAVYVLRQGQILTHG 218


                  ....*..
gi 1834229548 508 DAQSIFA 514
Cdd:PRK13638  219 APGEVFA 225
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
4-246 8.84e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 98.24  E-value: 8.84e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGERCQR--VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhPSGTIEYSgQNLLN 81
Cdd:PRK13633    2 NEMIKCKNVSYKYESNEESTEklALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLI------PSEGKVYV-DGLDT 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHIRgNRIAMIFQepmtslNPLHSIEKQI--------NEVLGIHKGLIgkvaTKRTLELLEMVGIPEPEKRLka 153
Cdd:PRK13633   75 SDEENLWDIR-NKAGMVFQ------NPDNQIVATIveedvafgPENLGIPPEEI----RERVDESLKKVGMYEYRRHA-- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 154 lPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQR 233
Cdd:PRK13633  142 -PHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDS 219

                         250
                  ....*....|...
gi 1834229548 234 GCIVEQASCEQLF 246
Cdd:PRK13633  220 GKVVMEGTPKEIF 232
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 255-515 1.03e-22

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 101.75  E-value: 1.03e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 255 RELLAAEPSGTPATNVVGP-PMLTVEDLKVWFPIKKGLLkktvdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLGlail 333
Cdd:COG4618   309 NELLAAVPAEPERMPLPRPkGRLSVENLTVVPPGSKRPI---------LRGVSFSLEPGEVLGVIGPSGSGKSTLA---- 375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 334 RLI-G----SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDP--F-GSlsprmcvsqiVGEGlrIHKMGtEAEQEqAII 405
Cdd:COG4618   376 RLLvGvwppTAGSVRLDGADLSQWDREE---LGRHIGYLPQDVelFdGT----------IAEN--IARFG-DADPE-KVV 438

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 406 AALKEVGLdpetrhrypHEF-------------------SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVEL 466
Cdd:COG4618   439 AAAKLAGV---------HEMilrlpdgydtrigeggarlSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAA 509

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1834229548 467 LRSLQSKyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:COG4618   510 IRALKAR-GATVVVITHRPSLLAA-VDKLLVLRDGRVQAFGPRDEVLAR 556
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 24-237 1.18e-22

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 94.42  E-value: 1.18e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvTAHSILrllpyplarhpSGTIEY-SGQnllnlkektIRhIRGnriamifqEP 102
Cdd:cd03216    14 KALDGVSLSVRRGEVHALLGENGAGKS-TLMKIL-----------SGLYKPdSGE---------IL-VDG--------KE 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNPLHSIEkqinevLGIhkgligkvatkrtlellEMVgipepekrlkalpHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03216    64 VSFASPRDARR------AGI-----------------AMV-------------YQLSVGERQMVEIARALARNARLLILD 107

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:cd03216   108 EPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 2-246 1.22e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 97.75  E-value: 1.22e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLAveFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPLarhpSGTIEYSGqnlLN 81
Cdd:PRK13632    3 NKSVMIKVENVS--FSYPNSENNALKNVSFEINEGEYVAILGHNGSGKS-TISKILTGLLKPQ----SGEIKIDG---IT 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHIRGNrIAMIFQEPMtslnplhsiekqiNEVLGI-----------HKGLIGKVATKRTLELLEMVGIpepEKR 150
Cdd:PRK13632   73 ISKENLKEIRKK-IGIIFQNPD-------------NQFIGAtveddiafgleNKKVPPKKMKDIIDDLAKKVGM---EDY 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 151 LKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKrIAHRVCV 230
Cdd:PRK13632  136 LDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIV 214

                         250
                  ....*....|....*.
gi 1834229548 231 MQRGCIVEQASCEQLF 246
Cdd:PRK13632  215 FSEGKLIAQGKPKEIL 230
cbiO PRK13641
energy-coupling factor transporter ATPase;
29-250 1.27e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 97.98  E-value: 1.27e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKS-VTAHSILRLLPyplarhPSGTIEYSGQNL-LNLKEKTIRHIRgNRIAMIFQEPMTSL 106
Cdd:PRK13641   26 ISFELEEGSFVALVGHTGSGKStLMQHFNALLKP------SSGTITIAGYHItPETGNKNLKKLR-KKVSLVFQFPEAQL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 107 NPlHSIEKQInEVLGIHKGLIGKVATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTT 186
Cdd:PRK13641   99 FE-NTVLKDV-EFGPKNFGFSEDEAKEKALKWLKKVGLSE--DLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 187 ALDVTVQLKILELLKELQaRLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQ 250
Cdd:PRK13641  175 GLDPEGRKEMMQLFKDYQ-KAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKE 237
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 29-281 1.41e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 97.78  E-value: 1.41e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLN-LKEKTIRHIRgNRIAMIFQEPMTSLN 107
Cdd:PRK13634   26 VNVSIPSGSYVAIIGHTGSGKS----TLLQHLN-GLLQPTSGTVTIGERVITAgKKNKKLKPLR-KKVGIVFQFPEHQLF 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 108 PlHSIEKQIneVLG-IHKGLIGKVATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTT 186
Cdd:PRK13634  100 E-ETVEKDI--CFGpMNFGVSEEDAKQKAREMIELVGLPE--ELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 187 ALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPqhpytrELLAAEPSGTP 266
Cdd:PRK13634  175 GLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP------DELEAIGLDLP 248

                         250       260
                  ....*....|....*....|....*..
gi 1834229548 267 ATN------------VVGPPMLTVEDL 281
Cdd:PRK13634  249 ETVkfkraleekfgiSFPKPCLTLEEL 275
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
 302-518 1.42e-22

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 101.94  E-value: 1.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGlailRLIG-----SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPF---G 373
Cdd:TIGR03796 495 IENFSLTLQPGQRVALVGGSGSGKSTIA----KLVAglyqpWSGEILFDGIPREEIPREV---LANSVAMVDQDIFlfeG 567

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SlsprmcvsqiVGEGLrihKMGTEAEQEQAIIAALKEVGLDPETRHR---YPHE-------FSGGQRQRIAIARALVLKP 443
Cdd:TIGR03796 568 T----------VRDNL---TLWDPTIPDADLVRACKDAAIHDVITSRpggYDAElaegganLSGGQRQRLEIARALVRNP 634

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 444 ALILLDEPTSALDRTVQRQVVELLRslqsKYNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQGDAQSIFAAPQH 518
Cdd:TIGR03796 635 SILILDEATSALDPETEKIIDDNLR----RRGCTCIIVAHRLSTIRD-CDEIIVLERGKVVQRGTHEELWAVGGA 704
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
301-528 1.43e-22

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 101.33  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDPFgslsprm 379
Cdd:PRK10789  330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDvSEGDIRFHDI---PLTKLQLDSWRSRLAVVSQTPF------- 399

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 CVSQIVGEGLRIHKMG-TEAEQEQAiiAALKEV---------GLDPETRHRYPHeFSGGQRQRIAIARALVLKPALILLD 449
Cdd:PRK10789  400 LFSDTVANNIALGRPDaTQQEIEHV--ARLASVhddilrlpqGYDTEVGERGVM-LSGGQKQRISIARALLLNAEILILD 476

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 450 EPTSALDRTVQRQVVELLRslQSKYNLTYLFISHDL-AVVKAlsHQLMVVKQGQVVEQGDAQSIFAAP---QHPYTQQLL 525
Cdd:PRK10789  477 DALSAVDGRTEHQILHNLR--QWGEGRTVIISAHRLsALTEA--SEILVMQHGHIAQRGNHDQLAQQSgwyRDMYRYQQL 552


                  ...
gi 1834229548 526 EAA 528
Cdd:PRK10789  553 EAA 555
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 4-245 1.51e-22

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 96.20  E-value: 1.51e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVefVVGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplARhpSGTIEYSGQNLLNLK 83
Cdd:COG0410     1 MPMLEVENLHA--GYGGI--HVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLP---PR--SGSIRFDGEDITGLP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 -EKTIRhiRGnrIAM------IFqepmtslnPLHSIEKqiNEVLGIHKGLiGKVATKRTLE-LLEMVgiPEPEKRLKALP 155
Cdd:COG0410    72 pHRIAR--LG--IGYvpegrrIF--------PSLTVEE--NLLLGAYARR-DRAEVRADLErVYELF--PRLKERRRQRA 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 HELSGGQRQRVMIAMALANEPELLIADEPTTAL---------DVTVQLkilellkelqARLGMALLLISHDLNLVKRIAH 226
Cdd:COG0410   135 GTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLapliveeifEIIRRL----------NREGVTILLVEQNARFALEIAD 204

                         250
                  ....*....|....*....
gi 1834229548 227 RVCVMQRGCIVEQASCEQL 245
Cdd:COG0410   205 RAYVLERGRIVLEGTAAEL 223
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 7-237 1.80e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 97.85  E-value: 1.80e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCQ-RVVEGVSFDIKRGETLALVGESGSGKSV-TAHSILRLLPyplarhPSGTIEYSGQNLLNLKE 84
Cdd:PRK13651    3 IKVKNIVKIFNKKLPTElKALDNVSVEINQGEFIAIIGQTGSGKTTfIEHLNALLLP------DTGTIEWIFKDEKNKKK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 ---------------------KTIRHIRgNRIAMIFQEPMTSLNPlHSIEKQIneVLG-IHKGLIGKVATKRTLELLEMV 142
Cdd:PRK13651   77 tkekekvleklviqktrfkkiKKIKEIR-RRVGVVFQFAEYQLFE-QTIEKDI--IFGpVSMGVSKEEAKKRAAKYIELV 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 143 GIPEpeKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALD-VTVQLKILELLKELQArlGMALLLISHDLNLV 221
Cdd:PRK13651  153 GLDE--SYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDpQGVKEILEIFDNLNKQ--GKTIILVTHDLDNV 228

                         250
                  ....*....|....*.
gi 1834229548 222 KRIAHRVCVMQRGCIV 237
Cdd:PRK13651  229 LEWTKRTIFFKDGKII 244
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 29-265 1.85e-22

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 98.65  E-value: 1.85e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEpmTSLNP 108
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKT----TLIRLIA-GLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRRIGYVFQE--ARLFP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 LHSIEKqiNEVLGIHKGLiGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTAL 188
Cdd:TIGR02142  89 HLSVRG--NLRYGMKRAR-PSERRISFERVIELLGI---GHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAAL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 189 DVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYtrelLAAEPSGT 265
Cdd:TIGR02142 163 DDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW----LAREDQGS 235
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
 307-528 2.08e-22

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 95.69  E-value: 2.08e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 307 FSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQldsltqqqVRPLRREMQVVFQDPFGSLSPRMCVSQIV 385
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPpAKGTVKVAGAS--------PGKGWRHIGYVPQRHEFAWDFPISVAHTV 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 386 GEGlRIHKMG----TEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQR 461
Cdd:TIGR03771  73 MSG-RTGHIGwlrrPCVADFAAVRDALRRVGLT-ELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQE 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 462 QVVELLRSLQSKYNlTYLFISHDLAVVKALSHQLMVVkQGQVVEQGdaqsifaapqHPytQQLLEAA 528
Cdd:TIGR03771 151 LLTELFIELAGAGT-AILMTTHDLAQAMATCDRVVLL-NGRVIADG----------TP--QQLQDPA 203
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 305-516 2.11e-22

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 100.69  E-value: 2.11e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPfgslsprMCVSQI 384
Cdd:PRK11174  369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQGSLKINGIELRELDPES---WRKHLSWVGQNP-------QLPHGT 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 385 VGEGLRihkMGTEAEQEQAIIAALKEVGLD---PETRHRYPHE-------FSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:PRK11174  439 LRDNVL---LGNPDASDEQLQQALENAWVSeflPLLPQGLDTPigdqaagLSVGQAQRLALARALLQPCQLLLLDEPTAS 515

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 455 LDRTVQRQVVELLRslQSKYNLTYLFISHDLAVVKALShQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:PRK11174  516 LDAHSEQLVMQALN--AASRRQTTLMVTHQLEDLAQWD-QIWVMQDGQIVQQGDYAELSQAG 574
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
6-249 3.07e-22

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 95.95  E-value: 3.07e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVefVVGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYSGQNLL 80
Cdd:COG4559     1 MLEAENLSV--RLGGR--TLLDDVSLTLRPGELTAIIGPNGAGKS----TLLKLLtgeltPS------SGEVRLNGRPLA 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRHIRgnriAMIFQEpmTSLN-PLHsiekqINEV--LG-IHKGLIGKVATKRTLELLEMVGIPEPEKRLKalpH 156
Cdd:COG4559    67 AWSPWELARRR----AVLPQH--SSLAfPFT-----VEEVvaLGrAPHGSSAAQDRQIVREALALVGLAHLAGRSY---Q 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 ELSGGQRQRVMIAMALA-------NEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVC 229
Cdd:COG4559   133 TLSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQL-ARRGGGVVAVLHDLNLAAQYADRIL 211

                         250       260
                  ....*....|....*....|
gi 1834229548 230 VMQRGCIVEQASCEQLFRAP 249
Cdd:COG4559   212 LLHQGRLVAQGTPEEVLTDE 231
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 6-256 3.85e-22

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 95.61  E-value: 3.85e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNLLNLKEK 85
Cdd:PRK14239    5 ILQVSDLSVYY----NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRhIRgNRIAMIFQEPmtslNPL-HSIEKqiNEVLGIH-KGLIGKVATKRTLEL-LEMVGI-PEPEKRLKALPHELSGG 161
Cdd:PRK14239   81 TVD-LR-KEIGMVFQQP----NPFpMSIYE--NVVYGLRlKGIKDKQVLDEAVEKsLKGASIwDEVKDRLHDSALGLSGG 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMalLLISHDLNLVKRIAHRVCVMQRGCIVEQAS 241
Cdd:PRK14239  153 QQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTM--LLVTRSMQQASRISDRTGFFLDGDLIEYND 230

                         250
                  ....*....|....*
gi 1834229548 242 CEQLFRAPQHPYTRE 256
Cdd:PRK14239  231 TKQMFMNPKHKETED 245
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 292-507 3.99e-22

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 94.65  E-value: 3.99e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQV------RPLRREM 364
Cdd:cd03269     6 VTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGeVLFDGKPLDIAARNRIgylpeeRGLYPKM 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 365 QVVFQ-DPFGSLsprmcvsqivgEGLRIHkmgtEAEQEqaIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKP 443
Cdd:cd03269    86 KVIDQlVYLAQL-----------KGLKKE----EARRR--IDEWLERLELS-EYANKRVEELSKGNQQKVQFIAAVIHDP 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 444 ALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03269   148 ELLILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 6-190 5.64e-22

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 94.08  E-value: 5.64e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEK 85
Cdd:COG4133     2 MLEAENLSCRR--GER--LLFSGLSFTLAAGEALALTGPNGSGKT----TLLRIL-AGLLPPSAGEVLWNGEPIRDARED 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIrgnriAMIFQEPM--TSLNPLhsiekqinEVLGIHKGLIGKVATKRTL-ELLEMVGIpepEKRLKALPHELSGGQ 162
Cdd:COG4133    73 YRRRL-----AYLGHADGlkPELTVR--------ENLRFWAALYGLRADREAIdEALEAVGL---AGLADLPVRQLSAGQ 136

                         170       180
                  ....*....|....*....|....*...
gi 1834229548 163 RQRVMIAMALANEPELLIADEPTTALDV 190
Cdd:COG4133   137 KRRVALARLLLSPAPLWLLDEPFTALDA 164
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 304-484 5.75e-22

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 94.46  E-value: 5.75e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLgLAILRLI--GSKGGIRFEGKQLDSLTQQQVRPLR-REMQVVFQDPFgsLSPRMC 380
Cdd:PRK10584   28 GVELVVKRGETIALIGESGSGKSTL-LAILAGLddGSSGEVSLVGQPLHQMDEEARAKLRaKHVGFVFQSFM--LIPTLN 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRIHKMGTEAEQEQAIiAALKEVGLDPETRHrYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQ 460
Cdd:PRK10584  105 ALENVELPALLRGESSRQSRNGAK-ALLEQLGLGKRLDH-LPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTG 182

                         170       180
                  ....*....|....*....|....
gi 1834229548 461 RQVVELLRSLQSKYNLTYLFISHD 484
Cdd:PRK10584  183 DKIADLLFSLNREHGTTLILVTHD 206
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 253-515 6.24e-22

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 99.34  E-value: 6.24e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 253 YTR--ELLAAEPSGTPATNVVGPP-MLTVEDLKVWFPIKKgllkKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLG 329
Cdd:TIGR01842 291 YKRlnELLANYPSRDPAMPLPEPEgHLSVENVTIVPPGGK----KPT-----LRGISFSLQAGEALAIIGPSGSGKSTLA 361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 330 LAILRLIG-SKGGIRFEGKQLDSLTQQQVRP----LRREMQVVfqdpfgslsprmcvSQIVGEGlrIHKMGTEAEQEQaI 404
Cdd:TIGR01842 362 RLIVGIWPpTSGSVRLDGADLKQWDRETFGKhigyLPQDVELF--------------PGTVAEN--IARFGENADPEK-I 424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 405 IAALKEVGLDpETRHRYPHEF-----------SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSK 473
Cdd:TIGR01842 425 IEAAKLAGVH-ELILRLPDGYdtvigpggatlSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKAR 503

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1834229548 474 yNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:TIGR01842 504 -GITVVVITHRPSLL-GCVDKILVLQDGRIARFGERDEVLAK 543
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 3-246 6.86e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 95.68  E-value: 6.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   3 QDNLIEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSV---TAHSILRLLPYPLARHpSGTIEYSGQNL 79
Cdd:PRK13636    2 EDYILKVEELNYNYSDG---THALKGININIKKGEVTAILGGNGAGKSTlfqNLNGILKPSSGRILFD-GKPIDYSRKGL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  80 LNLKEKtirhirgnrIAMIFQEPMtslNPLHSIEKQINEVLG-IHKGLIGKVATKRTLELLEMVGIpepeKRLKALP-HE 157
Cdd:PRK13636   78 MKLRES---------VGMVFQDPD---NQLFSASVYQDVSFGaVNLKLPEDEVRKRVDNALKRTGI----EHLKDKPtHC 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:PRK13636  142 LSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVI 221


                  ....*....
gi 1834229548 238 EQASCEQLF 246
Cdd:PRK13636  222 LQGNPKEVF 230
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 294-512 7.08e-22

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 98.85  E-value: 7.08e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 294 KTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLI---GS-KGGIRFEGKQLdslTQQQVRPLRRE-MQVVF 368
Cdd:PRK13549   13 KTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTL-MKVLSGVyphGTyEGEIIFEGEEL---QASNIRDTERAgIAIIH 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDPfgSLSPRMCVSQIV------GEGLRIH--KMGTEAEQeqaiiaALKEVGLD--PETRHRyphEFSGGQRQRIAIARA 438
Cdd:PRK13549   89 QEL--ALVKELSVLENIflgneiTPGGIMDydAMYLRAQK------LLAQLKLDinPATPVG---NLGLGQQQLVEIAKA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 439 LVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:PRK13549  158 LNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGM 230
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
6-189 7.43e-22

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 99.41  E-value: 7.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPlarhPSGTIEYSGQNLLNLKEK 85
Cdd:PRK10535    4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKS-TLMNILGCLDKP----TSGTYRVAGQDVATLDAD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQE--PMTSLNPLHSIEkqineVLGIHKGLIGKVATKRTLELLEMVGIPEpekRLKALPHELSGGQR 163
Cdd:PRK10535   79 ALAQLRREHFGFIFQRyhLLSHLTAAQNVE-----VPAVYAGLERKQRLLRAQELLQRLGLED---RVEYQPSQLSGGQQ 150

                         170       180
                  ....*....|....*....|....*.
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALD 189
Cdd:PRK10535  151 QRVSIARALMNGGQVILADEPTGALD 176
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 5-249 7.83e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 95.25  E-value: 7.83e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFvvgERCQRVVEGVSFDIKRGETLALVGESGSGKSVtahsilrllpypLARHPSGTIE-YSGQNLLNLK 83
Cdd:PRK13652    2 HLIETRDLCYSY---SGSKEALNNINFIAPRNSRIAVIGPNGAGKST------------LFRHFNGILKpTSGSVLIRGE 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRGNR--IAMIFQEPMTSL-NPlhSIEKQIneVLG-IHKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELS 159
Cdd:PRK13652   67 PITKENIREVRkfVGLVFQNPDDQIfSP--TVEQDI--AFGpINLGLDEETVAHRVSSALHMLGLEELRDRV---PHHLS 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ 239
Cdd:PRK13652  140 GGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAY 219

                         250
                  ....*....|
gi 1834229548 240 ASCEQLFRAP 249
Cdd:PRK13652  220 GTVEEIFLQP 229
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
305-523 7.92e-22

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 96.87  E-value: 7.92e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLP-QGQTlGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQL-DSLTQQQVRPLRREMQVVFQDpfGSLSPRMCV 381
Cdd:PRK11144   17 VNLTLPaQGIT-AIFGRSGAGKTSLINAISGLTRpQKGRIVLNGRVLfDAEKGICLPPEKRRIGYVFQD--ARLFPHYKV 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 382 SQIVGEGLRiHKMgteAEQEQAIIAALkevGLDPETRhRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQR 461
Cdd:PRK11144   94 RGNLRYGMA-KSM---VAQFDKIVALL---GIEPLLD-RYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKR 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 462 QVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQ-HPYTQQ 523
Cdd:PRK11144  166 ELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSAmRPWLPK 228
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 6-248 1.06e-21

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 94.45  E-value: 1.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEfvVGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYSGQNLL 80
Cdd:PRK13548    2 MLEARNLSVR--LGGR--TLLDDVSLTLRPGEVVAILGPNGAGKS----TLLRALsgelsPD------SGEVRLNGRPLA 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKektiRHIRGNRIAMIFQEpmTSLN-PLhsiekQINEV--LGIHKGLIGKVATKRTL-ELLEMVGIPEPEKRLKalpH 156
Cdd:PRK13548   68 DWS----PAELARRRAVLPQH--SSLSfPF-----TVEEVvaMGRAPHGLSRAEDDALVaAALAQVDLAHLAGRDY---P 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 ELSGGQRQRVMIAMALA------NEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCV 230
Cdd:PRK13548  134 QLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVL 213

                         250
                  ....*....|....*...
gi 1834229548 231 MQRGCIVEQASCEQLFRA 248
Cdd:PRK13548  214 LHQGRLVADGTPAEVLTP 231
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 301-529 1.10e-21

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 94.85  E-value: 1.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQL---DSLTQQQVRP--LRREMQVVFQ--DPFg 373
Cdd:PRK14243   25 AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLIPGFRVEGKVTfhgKNLYAPDVDPveVRRRIGMVFQkpNPF- 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 slsPRMCVSQIvGEGLRIHkmGTEAEQEQAIIAALKEVGLDPETRHRYPHE---FSGGQRQRIAIARALVLKPALILLDE 450
Cdd:PRK14243  104 ---PKSIYDNI-AYGARIN--GYKGDMDELVERSLRQAALWDEVKDKLKQSglsLSGGQQQRLCIARAIAVQPEVILMDE 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKYnlTYLFISHDLAVVKALSHQLMVV---------KQGQVVEQGDAQSIFAAPQHPYT 521
Cdd:PRK14243  178 PCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAARVSDMTAFFnveltegggRYGYLVEFDRTEKIFNSPQQQAT 255


                  ....*...
gi 1834229548 522 QQLLEAAF 529
Cdd:PRK14243  256 RDYVSGRF 263
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 13-260 1.51e-21

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 94.78  E-value: 1.51e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  13 AVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNLLNLKEktIRHIRg 92
Cdd:PRK14271   24 AVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFNYRD--VLEFR- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  93 NRIAMIFQEPmtslNPL-HSIEKQINEVLGIHKGLIGK----VATKRTLEllemVGIPEPEK-RLKALPHELSGGQRQRV 166
Cdd:PRK14271  101 RRVGMLFQRP----NPFpMSIMDNVLAGVRAHKLVPRKefrgVAQARLTE----VGLWDAVKdRLSDSPFRLSGGQQQLL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 167 MIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLgmALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF 246
Cdd:PRK14271  173 CLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLF 250

                         250
                  ....*....|....
gi 1834229548 247 RAPQHPYTRELLAA 260
Cdd:PRK14271  251 SSPKHAETARYVAG 264
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 300-507 1.93e-21

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 98.27  E-value: 1.93e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQvrpLRREMQVVFQDPF---GS- 374
Cdd:TIGR01193 488 NILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGeILLNGFSLKDIDRHT---LRQFINYLPQEPYifsGSi 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 -----LSPRMCVSQ-IVGEGLRIHKMGTEAEQEQaiiaalkeVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILL 448
Cdd:TIGR01193 565 lenllLGAKENVSQdEIWAACEIAEIKDDIENMP--------LGYQTELSEE-GSSISGGQKQRIALARALLTDSKVLIL 635

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 449 DEPTSALDRTVQRQVVELLRSLQSKynlTYLFISHDLAVVKaLSHQLMVVKQGQVVEQG 507
Cdd:TIGR01193 636 DESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVAK-QSDKIIVLDHGKIIEQG 690
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 7-245 2.07e-21

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 93.06  E-value: 2.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:cd03253     1 IEFENVTFAYDPG---RPVLKDVSFTIPAGKKVAIVGPSGSGKS----TILRLL-FRFYDVSSGSILIDGQDIREVTLDS 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRhirgNRIAMIFQEpmTSL------------NPLHSIEKQIN--EVLGIH---KGLIGKVATkrtlelleMVGipepEK 149
Cdd:cd03253    73 LR----RAIGVVPQD--TVLfndtigynirygRPDATDEEVIEaaKAAQIHdkiMRFPDGYDT--------IVG----ER 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 150 RLKalpheLSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQlkilellKELQARL-----GMALLLISHDLNLVKRi 224
Cdd:cd03253   135 GLK-----LSGGEKQRVAIARAILKNPPILLLDEATSALDTHTE-------REIQAALrdvskGRTTIVIAHRLSTIVN- 201

                         250       260
                  ....*....|....*....|.
gi 1834229548 225 AHRVCVMQRGCIVEQASCEQL 245
Cdd:cd03253   202 ADKIIVLKDGRIVERGTHEEL 222
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 7-240 2.41e-21

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 92.28  E-value: 2.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLKEKT 86
Cdd:cd03268     1 LKTNDLTKTY--GKK--RVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLI-----KPDSGEITFDGKSYQKNIEAL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 irhirgNRIAMIFQEPmtSLNPLHSIEKQinevLGIHKGLIGkVATKRTLELLEMVGIPEPEKRLKALpheLSGGQRQRV 166
Cdd:cd03268    72 ------RRIGALIEAP--GFYPNLTAREN----LRLLARLLG-IRKKRIDEVLDVVGLKDSAKKKVKG---FSLGMKQRL 135

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 167 MIAMALANEPELLIADEPTTALDvTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQA 240
Cdd:cd03268   136 GIALALLGNPDLLILDEPTNGLD-PDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
275-533 2.59e-21

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 93.54  E-value: 2.59e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVwfpikkGLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLT 353
Cdd:PRK11231    2 TLRTENLTV------GYGTKRI-----LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGtVFLGDKPISMLS 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQvrpLRREMQVVFQDPfgsLSPR-MCVSQIVGEGLRIHK--MGTEAEQEQAIIA-ALKEVGLDpETRHRYPHEFSGGQ 429
Cdd:PRK11231   71 SRQ---LARRLALLPQHH---LTPEgITVRELVAYGRSPWLslWGRLSAEDNARVNqAMEQTRIN-HLADRRLTDLSGGQ 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGda 509
Cdd:PRK11231  144 RQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQG-- 220

                         250       260
                  ....*....|....*....|....
gi 1834229548 510 qsifaAPQHPYTQQLLEAAFLVPA 533
Cdd:PRK11231  221 -----TPEEVMTPGLLRTVFDVEA 239
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 273-515 3.97e-21

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 92.45  E-value: 3.97e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWFPI--------KKGLL---KKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG---- 337
Cdd:COG1134     2 SSMIEVENVSKSYRLyhepsrslKELLLrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTL----LKLIAgile 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 338 -SKGGIRFEGKqldsltqqqVRPLrREMQVVFQdpfGSLSPRmcvsqivgE----GLRIHKMgTEAEQEQAI--IAALKE 410
Cdd:COG1134    78 pTSGRVEVNGR---------VSAL-LELGAGFH---PELTGR--------EniylNGRLLGL-SRKEIDEKFdeIVEFAE 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 411 VG--LDPETRHrypheFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVV 488
Cdd:COG1134   136 LGdfIDQPVKT-----YSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAV 209

                         250       260
                  ....*....|....*....|....*..
gi 1834229548 489 KALSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:COG1134   210 RRLCDRAIWLEKGRLVMDGDPEEVIAA 236
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 300-507 4.00e-21

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 91.70  E-value: 4.00e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEGKQLDSLtqqQVRPLRREMQVVFQDPfgslspr 378
Cdd:cd03369    22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLeAEEGKIEIDGIDISTI---PLEDLRSSLTIIPQDP------- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSQIVGEGLRIHKMGTEAEqeqaIIAALK--EVGLDpetrhrypheFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:cd03369    92 TLFSGTIRSNLDPFDEYSDEE----IYGALRvsEGGLN----------LSQGQRQLLCLARALLKRPRVLVLDEATASID 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 457 RTVQRQVVELLRSLQSkyNLTYLFISHDLAVVkALSHQLMVVKQGQVVEQG 507
Cdd:cd03369   158 YATDALIQKTIREEFT--NSTILTIAHRLRTI-IDYDKILVMDAGEVKEYD 205
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
30-245 4.31e-21

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 92.34  E-value: 4.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  30 SFDIKRGETLALVGESGSGKSvtahSILRLLPYPLARHpsgtieySGQNLLNLKEKTIRHIRGNRIAMIFQEpmTSLNPL 109
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKS----TLLNLIAGFLTPA-------SGSLTLNGQDHTTTPPSRRPVSMLFQE--NNLFSH 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 110 HSIEKQINevLGIHKGLIGKVATKRTLE-LLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTAL 188
Cdd:PRK10771   86 LTVAQNIG--LGLNPGLKLNAAQREKLHaIARQMGI---EDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSAL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 189 DVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:PRK10771  161 DPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 25-246 4.46e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 94.15  E-value: 4.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIE----YSGQNLLNL---------KEKTIRHIR 91
Cdd:PRK13631   41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLI-----KSKYGTIQvgdiYIGDKKNNHelitnpyskKIKNFKELR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  92 gNRIAMIFQEPMTSLNPlHSIEKQIN---EVLGIHKgligKVATKRTLELLEMVGIPEPekRLKALPHELSGGQRQRVMI 168
Cdd:PRK13631  116 -RRVSMVFQFPEYQLFK-DTIEKDIMfgpVALGVKK----SEAKKLAKFYLNKMGLDDS--YLERSPFGLSGGQKRRVAI 187

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 169 AMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF 246
Cdd:PRK13631  188 AGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIF 264
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
1-249 4.86e-21

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 94.40  E-value: 4.86e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLl 80
Cdd:PRK11432    1 MTQKNFVVLKNITKRF--GS--NTVIDNLNLTIKQGTMVTLLGPSGCGKT----TVLRLVA-GLEKPTEGQIFIDGEDV- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 nlkekTIRHIRGNRIAMIFQEpmTSLNPLHSIEKQIN---EVLGIHKGLIgkvaTKRTLELLEMVGIPEPEKRLKalpHE 157
Cdd:PRK11432   71 -----THRSIQQRDICMVFQS--YALFPHMSLGENVGyglKMLGVPKEER----KQRVKEALELVDLAGFEDRYV---DQ 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:PRK11432  137 ISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIM 216

                         250
                  ....*....|..
gi 1834229548 238 EQASCEQLFRAP 249
Cdd:PRK11432  217 QIGSPQELYRQP 228
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 302-512 6.68e-21

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 92.07  E-value: 6.68e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQvrpLRREMQVVFQDPfgSLSPRMC 380
Cdd:COG4604    17 LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGeVLVDGLDVATTPSRE---LAKRLAILRQEN--HINSRLT 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRIHKMG--TeAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:COG4604    92 VRELVAFGRFPYSKGrlT-AEDREIIDEAIAYLDLED-LADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMK 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 459 VQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:COG4604   170 HSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
cbiO PRK13640
energy-coupling factor transporter ATPase;
4-250 6.72e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 92.94  E-value: 6.72e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLARH--PSGTIEYSGqnlLN 81
Cdd:PRK13640    3 DNIVEFKH--VSFTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKS----TISKLINGLLLPDdnPNSKITVDG---IT 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHIRgNRIAMIFQEPMtslnplhsiekqiNEVLGIHKGliGKVATKrtlelLEMVGIPEPEKR----------- 150
Cdd:PRK13640   74 LTAKTVWDIR-EKVGIVFQNPD-------------NQFVGATVG--DDVAFG-----LENRAVPRPEMIkivrdvladvg 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 151 ----LKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKrIAH 226
Cdd:PRK13640  133 mldyIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MAD 211

                         250       260
                  ....*....|....*....|....
gi 1834229548 227 RVCVMQRGCIVEQASCEQLFRAPQ 250
Cdd:PRK13640  212 QVLVLDDGKLLAQGSPVEIFSKVE 235
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
301-507 8.26e-21

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 95.86  E-value: 8.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTqqqVRPLRREMQVV------FQDPFG 373
Cdd:PRK11176  358 ALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDiDEGEILLDGHDLRDYT---LASLRNQVALVsqnvhlFNDTIA 434

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 -----SLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLdpetrhryphEFSGGQRQRIAIARALVLKPALILL 448
Cdd:PRK11176  435 nniayARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGV----------LLSGGQRQRIAIARALLRDSPILIL 504

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 449 DEPTSALDRTVQRQVVELLRSLQSkyNLTYLFISHDLAVVKAlSHQLMVVKQGQVVEQG 507
Cdd:PRK11176  505 DEATSALDTESERAIQAALDELQK--NRTSLVIAHRLSTIEK-ADEILVVEDGEIVERG 560
cbiO PRK13643
energy-coupling factor transporter ATPase;
300-513 9.06e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 92.49  E-value: 9.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQ-QVRPLRREMQVVFQDPFGSLSP 377
Cdd:PRK13643   20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQpTEGKVTVGDIVVSSTSKQkEIKPVRKKVGVVFQFPESQLFE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIvgeGLRIHKMGTEAEQEQAIIA-ALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PRK13643  100 ETVLKDV---AFGPQNFGIPKEKAEKIAAeKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLD 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 457 RTVQRQVVELLRSLQsKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIF 513
Cdd:PRK13643  177 PKARIEMMQLFESIH-QSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 304-503 1.05e-20

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 90.99  E-value: 1.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKqldSLTQQQVRPLRREMQVVFQDPfgSLSPRmCVS 382
Cdd:cd03248    32 DVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGqVLLDGK---PISQYEHKYLHSKVSLVGQEP--VLFAR-SLQ 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 383 QIVGEGLRIHKMGTEAEQEQAIIA----ALKEVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:cd03248   106 DNIAYGLQSCSFECVKEAAQKAHAhsfiSELASGYDTEVGEK-GSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAE 184

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 459 VQRQVVELLRslQSKYNLTYLFISHDLAVVKAlSHQLMVVKQGQV 503
Cdd:cd03248   185 SEQQVQQALY--DWPERRTVLVIAHRLSTVER-ADQILVLDGGRI 226
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 289-507 1.47e-20

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 90.85  E-value: 1.47e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 289 KGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILR--LIGSKGGIRFEGkqLDSLTQQqvRPLRREMQV 366
Cdd:cd03267    24 KSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTT-LKILSglLQPTSGEVRVAG--LVPWKRR--KKFLRRIGV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VF---QDPFGSLSPRmcvsqivgEGLRIHKM-----GTEAEQEQAIIAALKEVG--LDPETRhryphEFSGGQRQRIAIA 436
Cdd:cd03267    99 VFgqkTQLWWDLPVI--------DSFYLLAAiydlpPARFKKRLDELSELLDLEelLDTPVR-----QLSLGQRMRAEIA 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 437 RALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03267   166 AALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 294-512 1.48e-20

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 94.89  E-value: 1.48e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 294 KTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLI---GS-KGGIRFEGKQLDSltqQQVRPLRREMQVVFQ 369
Cdd:TIGR02633   9 KTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTL-MKILSGVyphGTwDGEIYWSGSPLKA---SNIRDTERAGIVIIH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 370 DPFgSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAA---LKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:TIGR02633  85 QEL-TLVPELSVAENIFLGNEITLPGGRMAYNAMYLRAknlLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQARLL 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:TIGR02633 164 ILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTM 228
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 275-512 1.56e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 92.09  E-value: 1.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKvwfpikkgllkKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLT 353
Cdd:COG4152     1 MLELKGLT-----------KRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGeVLWDGEPLDPED 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQV------RPLRREM----QVVFqdpFGSLsprmcvsqivgEGLrihkmgTEAEQEQAIIAALKEVGLdPETRHRYPH 423
Cdd:COG4152    70 RRRIgylpeeRGLYPKMkvgeQLVY---LARL-----------KGL------SKAEAKRRADEWLERLGL-GDRANKKVE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 424 EFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:COG4152   129 ELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRK 207


                  ....*....
gi 1834229548 504 VEQGDAQSI 512
Cdd:COG4152   208 VLSGSVDEI 216
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 29-249 1.58e-20

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 93.24  E-value: 1.58e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNlKEKTIR---HIRgnRIAMIFQEPmtS 105
Cdd:COG4148    18 VDFTLPGRGVTALFGPSGSGKT----TLLRAIA-GLERPDSGRIRLGGEVLQD-SARGIFlppHRR--RIGYVFQEA--R 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LNPLHSIEKqiNEVLGIHKglIGKVATKRTL-ELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEP 184
Cdd:COG4148    88 LFPHLSVRG--NLLYGRKR--APRAERRISFdEVVELLGI---GHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEP 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 185 TTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAP 249
Cdd:COG4148   161 LAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 25-246 1.86e-20

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 90.36  E-value: 1.86e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarHPSGTIEYSGQNLLNLKEKTIRhirgNRIAMIFQEP-- 102
Cdd:cd03254    18 VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYD-----PQKGQILIDGIDIRDISRKSLR----SMIGVVLQDTfl 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 ----------MTSLNPLHSIEKQINEVLGIHKgLIgkvatkRTLE--LLEMVGipepEKrlkalPHELSGGQRQRVMIAM 170
Cdd:cd03254    89 fsgtimenirLGRPNATDEEVIEAAKEAGAHD-FI------MKLPngYDTVLG----EN-----GGNLSQGERQLLAIAR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 171 ALANEPELLIADEPTTALDV----TVQLKILELlkelqaRLGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQASCEQLF 246
Cdd:cd03254   153 AMLRDPKILILDEATSNIDTetekLIQEALEKL------MKGRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTHDELL 225
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
23-234 2.19e-20

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 89.93  E-value: 2.19e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKTIRHIRgNRIAMIFQEP 102
Cdd:PRK10908   15 RQALQGVTFHMRPGEMAFLTGHSGAGKS----TLLKLI-CGIERPSAGKIWFSGHDITRLKNREVPFLR-RQIGMIFQDH 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNplHSIEKQINEVLgIHKGLIGKVATKRTLELLEMVGIPEpekRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:PRK10908   89 HLLMD--RTVYDNVAIPL-IIAGASGDDIRRRVSAALDKVGLLD---KAKNFPIQLSGGEQQRVGIARAVVNKPAVLLAD 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 183 EPTTALDVTVQLKILELLKELQaRLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:PRK10908  163 EPTGNLDDALSEGILRLFEEFN-RVGVTVLMATHDIGLISRRSYRMLTLSDG 213
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 301-512 2.32e-20

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 89.89  E-value: 2.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSL-TQQQVRplrREMQVVFQ--DPFGSLS 376
Cdd:TIGR03410  15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGsIRLDGEDITKLpPHERAR---AGIAYVPQgrEIFPRLT 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prmcvsqiVGEGLRIhKMGTEAEQEQAIIA-------ALKEVgldpetRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:TIGR03410  92 --------VEENLLT-GLAALPRRSRKIPDeiyelfpVLKEM------LGRRGGDLSGGQQQQLAIARALVTRPKLLLLD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:TIGR03410 157 EPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 7-245 2.49e-20

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 89.98  E-value: 2.49e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLP--YPLArhpSGTIEYSGQNLLNLKE 84
Cdd:cd03251     1 VEFKN--VTFRYPGDGPPVLRDISLDIPAGETVALVGPSGSGKS----TLVNLIPrfYDVD---SGRILIDGHDVRDYTL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KTIRhirgNRIAMIFQEPMtslnpLHS--IEKQIN-EVLGIHKGLIGKVAtkRTLELLEMV-GIPE------PEKRLKal 154
Cdd:cd03251    72 ASLR----RQIGLVSQDVF-----LFNdtVAENIAyGRPGATREEVEEAA--RAANAHEFImELPEgydtviGERGVK-- 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 pheLSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQArlGMALLLISHDLNLVKRiAHRVCVMQRG 234
Cdd:cd03251   139 ---LSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTIEN-ADRIVVLEDG 212

                         250
                  ....*....|.
gi 1834229548 235 CIVEQASCEQL 245
Cdd:cd03251   213 KIVERGTHEEL 223
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 276-509 2.65e-20

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 90.13  E-value: 2.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 276 LTVEDLKVwfpikkgllkkTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILrliGS------KGGIRFEGKQL 349
Cdd:COG0396     1 LEIKNLHV-----------SVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLM---GHpkyevtSGSILLDGEDI 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 350 DSLTQQQvRPlRREMQVVFQDP----------FgsLspRMCVSQIVGEGLRIHKMGTEAEQeqaiiaALKEVGLDPETRH 419
Cdd:COG0396    67 LELSPDE-RA-RAGIFLAFQYPveipgvsvsnF--L--RTALNARRGEELSAREFLKLLKE------KMKELGLDEDFLD 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 420 RYPHE-FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHD---LAVVKAlsHQL 495
Cdd:COG0396   135 RYVNEgFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRSP-DRGILIITHYqriLDYIKP--DFV 211

                         250
                  ....*....|....
gi 1834229548 496 MVVKQGQVVEQGDA 509
Cdd:COG0396   212 HVLVDGRIVKSGGK 225
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 302-503 3.08e-20

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 88.04  E-value: 3.08e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDP--FGslspr 378
Cdd:cd03246    18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRpTSGRVRLDGADISQWDPNE---LGDHVGYLPQDDelFS----- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 mcvsqivgeglrihkmGTEAEqeqaIIaalkevgldpetrhrypheFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:cd03246    90 ----------------GSIAE----NI-------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVE 130

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 459 VQRQVVELLRSLQSKyNLTYLFISHDLAVVKALShQLMVVKQGQV 503
Cdd:cd03246   131 GERALNQAIAALKAA-GATRIVIAHRPETLASAD-RILVLEDGRV 173
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 23-260 3.43e-20

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 90.48  E-value: 3.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNLLNlKEKTIRHIRgNRIAMIFQEP 102
Cdd:PRK14258   20 QKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVRVEGRVEFFNQNIYE-RRVNLNRLR-RQVSMVHPKP 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 mtSLNPLhSIEKQIN---EVLGIHKGLIGKVATKRTLELLEMvgIPEPEKRLKALPHELSGGQRQRVMIAMALANEPELL 179
Cdd:PRK14258   98 --NLFPM-SVYDNVAygvKIVGWRPKLEIDDIVESALKDADL--WDEIKHKIHKSALDLSGGQQQRLCIARALAVKPKVL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 180 IADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQR-----GCIVEQASCEQLFRAPQHPYT 254
Cdd:PRK14258  173 LMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIFNSPHDSRT 252


                  ....*.
gi 1834229548 255 RELLAA 260
Cdd:PRK14258  253 REYVLS 258
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 6-250 3.45e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 90.52  E-value: 3.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSVT---AHSILRllpyplarhPSG--------TIEY 74
Cdd:PRK13639    1 ILETRDLKYSYPDG---TEALKGINFKAEKGEMVALLGPNGAGKSTLflhFNGILK---------PTSgevlikgePIKY 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  75 SGQNLLNLKEKtirhirgnrIAMIFQEPMTSL-NPlhSIEKQIneVLG-IHKGLIGKVATKRTLELLEMVGIPEPEKRLk 152
Cdd:PRK13639   69 DKKSLLEVRKT---------VGIVFQNPDDQLfAP--TVEEDV--AFGpLNLGLSKEEVEKRVKEALKAVGMEGFENKP- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 153 alPHELSGGQRQRVMIAMALANEPELLIADEPTTALDvTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:PRK13639  135 --PHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLD-PMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMS 211

                         250
                  ....*....|....*...
gi 1834229548 233 RGCIVEQASCEQLFRAPQ 250
Cdd:PRK13639  212 DGKIIKEGTPKEVFSDIE 229
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 33-239 4.75e-20

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 88.70  E-value: 4.75e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  33 IKRGETLALVGESGSGKSvtahSILRLLP-YPLARhpsgtieySGQNLLNLKEKTIRHIRGNRIAMIFQEpmTSLNPLHS 111
Cdd:cd03298    21 FAQGEITAIVGPSGSGKS----TLLNLIAgFETPQ--------SGRVLINGVDVTAAPPADRPVSMLFQE--NNLFAHLT 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 112 IEKQINevLGIHKGL-IGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLIADEPTTALDV 190
Cdd:cd03298    87 VEQNVG--LGLSPGLkLTAEDRQAIEVALARVGLAGLEKRL---PGELSGGERQRVALARVLVRDKPVLLLDEPFAALDP 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1834229548 191 TVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ 239
Cdd:cd03298   162 ALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQ 210
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 7-234 6.05e-20

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 88.33  E-value: 6.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERCQRVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPlarhPSGTIEYSGQNLLnlkeKT 86
Cdd:cd03263     1 LQIRNLTKTY--KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKT-TTLKMLTGELRP----TSGTAYINGYSIR----TD 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGNrIAMIFQEPM--TSLNPLhsiekqinEVLGIH---KGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGG 161
Cdd:cd03263    70 RKAARQS-LGYCPQFDAlfDELTVR--------EHLRFYarlKGLPKSEIKEEVELLLRVLGLTDKANKR---ARTLSGG 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALDV--------TVQLKilellkelqaRLGMALLLISHDLNLVKRIAHRVCVMQR 233
Cdd:cd03263   138 MKRKLSLAIALIGGPSVLLLDEPTSGLDPasrraiwdLILEV----------RKGRSIILTTHSMDEAEALCDRIAIMSD 207


                  .
gi 1834229548 234 G 234
Cdd:cd03263   208 G 208
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 275-508 6.94e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 90.53  E-value: 6.94e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVWFPIK----------KGLLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSK 339
Cdd:COG4586     1 IIEVENLSKTYRVYekepglkgalKGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTikmltGI----LVPTS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 340 GGIRFEGKqldsltqqqvRPLRREMQ------VVF-------QDpfgsLSPRmcvsqivgEGLRIHK--MGTEAEQEQAI 404
Cdd:COG4586    77 GEVRVLGY----------VPFKRRKEfarrigVVFgqrsqlwWD----LPAI--------DSFRLLKaiYRIPDAEYKKR 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 405 IAALKEV-GLDP--ETRHRyphEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFI 481
Cdd:COG4586   135 LDELVELlDLGEllDTPVR---QLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLT 211

                         250       260
                  ....*....|....*....|....*..
gi 1834229548 482 SHDLAVVKALSHQLMVVKQGQVVEQGD 508
Cdd:COG4586   212 SHDMDDIEALCDRVIVIDHGRIIYDGS 238
cbiO PRK13645
energy-coupling factor transporter ATPase;
293-514 7.99e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 89.68  E-value: 7.99e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 293 KKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEG--KQLDSLTQ-QQVRPLRREMQVVFQ 369
Cdd:PRK13645   18 KKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGdyAIPANLKKiKEVKRLRKEIGLVFQ 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 370 DPFGSLSpRMCVSQIVGEGlRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:PRK13645   98 FPEYQLF-QETIEKDIAFG-PVNLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLD 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:PRK13645  176 EPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS 240
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 25-256 8.36e-20

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 88.95  E-value: 8.36e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLP-YPLARHPSGTIEYSGQNLLNLKEKTIRhirgNRIAMIFQEPm 103
Cdd:PRK14246   25 ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiYDSKIKVDGKVLYFGKDIFQIDAIKLR----KEVGMVFQQP- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 tslNPLH--SIEKQINEVLGIHkGLIGKVATKRTLE-LLEMVGI-PEPEKRLKALPHELSGGQRQRVMIAMALANEPELL 179
Cdd:PRK14246  100 ---NPFPhlSIYDNIAYPLKSH-GIKEKREIKKIVEeCLRKVGLwKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVL 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 180 IADEPTTALDVTvqLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQHPYTRE 256
Cdd:PRK14246  176 LMDEPTSMIDIV--NSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEK 250
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 21-237 8.39e-20

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 88.54  E-value: 8.39e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  21 RCQRVVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLPYPLarHP-SGTIEYSGqnLLNLKEKtIRHIRgnRIAMIF 99
Cdd:cd03267    32 REVEALKGISFTIEKGEIVGFIGPNGAGKTTT----LKILSGLL--QPtSGEVRVAG--LVPWKRR-KKFLR--RIGVVF 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 100 QE---------PMTSLNPLHSIEKqinevlgihkglIGKVATKRTL-ELLEMVGIpepEKRLKALPHELSGGQRQRVMIA 169
Cdd:cd03267   101 GQktqlwwdlpVIDSFYLLAAIYD------------LPPARFKKRLdELSELLDL---EELLDTPVRQLSLGQRMRAEIA 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 170 MALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:cd03267   166 AALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 274-529 8.69e-20

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 91.44  E-value: 8.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFpikkgllkktvDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSL 352
Cdd:PRK09536    2 PMIDVSDLSVEF-----------GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTpTAGTVLVAGDDVEAL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 353 TqqqVRPLRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIH--KMGTEAEQEQAII-AALKEVGLDpETRHRYPHEFSGGQ 429
Cdd:PRK09536   71 S---ARAASRRVASVPQDT--SLSFEFDVRQVVEMGRTPHrsRFDTWTETDRAAVeRAMERTGVA-QFADRPVTSLSGGE 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:PRK09536  145 RQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPP 223

                         250       260
                  ....*....|....*....|
gi 1834229548 510 QSIFAAPQhpytqqlLEAAF 529
Cdd:PRK09536  224 ADVLTADT-------LRAAF 236
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 274-507 9.05e-20

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 88.89  E-value: 9.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVWFpikKGLLkktvdyvkAVDGINFSLPQGQTLGIVGESGSGKSTlglaILRLIG-----SKGGIRFEGKQ 348
Cdd:PRK11300    4 PLLSVSGLMMRF---GGLL--------AVNNVNLEVREQEIVSLIGPNGAGKTT----VFNCLTgfykpTGGTILLRGQH 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDSL------------TQQQVRpLRREMQVVfqdpfgslsPRMCVSQ--IVGEGLRIHKMGT----EAEQEQAIIAA--L 408
Cdd:PRK11300   69 IEGLpghqiarmgvvrTFQHVR-LFREMTVI---------ENLLVAQhqQLKTGLFSGLLKTpafrRAESEALDRAAtwL 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 409 KEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVV 488
Cdd:PRK11300  139 ERVGLL-EHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLV 217

                         250
                  ....*....|....*....
gi 1834229548 489 KALSHQLMVVKQGQVVEQG 507
Cdd:PRK11300  218 MGISDRIYVVNQGTPLANG 236
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 300-507 1.00e-19

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 86.60  E-value: 1.00e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILR--LIGSKGGIRFEGKQLDSLTQQqvrpLRREMQVVFQDPF---GS 374
Cdd:cd03247    16 QVLKNLSLELKQGEKIALLGRSGSGKSTL-LQLLTgdLKPQQGEITLDGVPVSDLEKA----LSSLISVLNQRPYlfdTT 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 375 LsprmcvsqivgeglrihkmgteaeqeqaiiaaLKEVGLdpetrhryphEFSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:cd03247    91 L--------------------------------RNNLGR----------RFSGGERQRLALARILLQDAPIVLLDEPTVG 128

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 455 LDRTVQRQVVELLrsLQSKYNLTYLFISHDLAVVKALShQLMVVKQGQVVEQG 507
Cdd:cd03247   129 LDPITERQLLSLI--FEVLKDKTLIWITHHLTGIEHMD-KILFLENGKIIMQG 178
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
26-245 1.14e-19

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 92.33  E-value: 1.14e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPlarhPSGTIEYSGQNLLNLKEKTIRHirgnRIAMIFQEPMTs 105
Cdd:PRK13657  351 VEDVSFEAKPGQTVAIVGPTGAGKS-TLINLLQRVFDP----QSGRILIDGTDIRTVTRASLRR----NIAVVFQDAGL- 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LNplHSIEKQInevlgihkgLIGKV-ATKRtlELLEMVG-------IPEPEKRLKALPHE----LSGGQRQRVMIAMALA 173
Cdd:PRK13657  421 FN--RSIEDNI---------RVGRPdATDE--EMRAAAEraqahdfIERKPDGYDTVVGErgrqLSGGERQRLAIARALL 487

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 174 NEPELLIADEPTTALDVTVqlkilellkelQARLGMAL---------LLISHDLNLVkRIAHRVCVMQRGCIVEQASCEQ 244
Cdd:PRK13657  488 KDPPILILDEATSALDVET-----------EAKVKAALdelmkgrttFIIAHRLSTV-RNADRILVFDNGRVVESGSFDE 555


                  .
gi 1834229548 245 L 245
Cdd:PRK13657  556 L 556
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 5-258 1.20e-19

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 88.36  E-value: 1.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFVVGErcqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNLLNLKE 84
Cdd:PRK14267    3 FAIETVNLRVYYGSNH----VIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNEEARVEGEVRLFGRNIYSPDV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KTIRHIRgnRIAMIFQEPmtslNPLHSIEKQINEVLGIHkgLIGKVATKRTLE------LLEMVGIPEPEKRLKALPHEL 158
Cdd:PRK14267   79 DPIEVRR--EVGMVFQYP----NPFPHLTIYDNVAIGVK--LNGLVKSKKELDervewaLKKAALWDEVKDRLNDYPSNL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTvqLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVE 238
Cdd:PRK14267  151 SGGQRQRLVIARALAMKPKILLMDEPTANIDPV--GTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIE 228

                         250       260
                  ....*....|....*....|
gi 1834229548 239 QASCEQLFRAPQHPYTRELL 258
Cdd:PRK14267  229 VGPTRKVFENPEHELTEKYV 248
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 25-248 1.43e-19

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 87.93  E-value: 1.43e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLAR-----HPSGTIE---YSGQNLLNLKEKTI--RHIRGNr 94
Cdd:cd03252    17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRvlvdgHDLALADpawLRRQVGVVLQENVLfnRSIRDN- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  95 IAMIFQEPmtslnPLHSIEkQINEVLGIHKGLigkvatkrtLELLE----MVGipepEKRLKalpheLSGGQRQRVMIAM 170
Cdd:cd03252    96 IALADPGM-----SMERVI-EAAKLAGAHDFI---------SELPEgydtIVG----EQGAG-----LSGGQRQRIAIAR 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 171 ALANEPELLIADEPTTALDVTVQLKILELLKELQArlGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQASCEQLFRA 248
Cdd:cd03252   152 ALIHNPRILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAE 226
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
7-234 1.56e-19

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 89.48  E-value: 1.56e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCqrVVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLpYPLARHPSGTIEYSGQNLlnlkEKT 86
Cdd:PRK13537    8 IDFRN--VEKRYGDKL--VVDGLSFHVQRGECFGLLGPNGAGKTTT----LRML-LGLTHPDAGSISLCGEPV----PSR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgNRIAMIFQepMTSLNPLHSIEKQInEVLGIHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRV 166
Cdd:PRK13537   75 ARHAR-QRVGVVPQ--FDNLDPDFTVRENL-LVFGRYFGLSAAAARALVPPLLEFAKL---ENKADAKVGELSGGMKRRL 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 167 MIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:PRK13537  148 TLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEG 214
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 300-484 1.93e-19

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 87.08  E-value: 1.93e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGS-----KGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDP--F 372
Cdd:PRK10247   21 KILNNISFSLRAGEFKLITGPSGCGKSTL----LKIVASlisptSGTLLFEGEDISTLKPEI---YRQQVSYCAQTPtlF 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 GslsprmcvsQIVGEGLRI-HKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:PRK10247   94 G---------DTVYDNLIFpWQIRNQQPDPAIFLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEI 164

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1834229548 452 TSALDRTVQRQVVELLRSLQSKYNLTYLFISHD 484
Cdd:PRK10247  165 TSALDESNKHNVNEIIHRYVREQNIAVLWVTHD 197
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 276-507 2.06e-19

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 87.20  E-value: 2.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 276 LTVEDLKVWFPIKKG---LLKKT--------VDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SK 339
Cdd:cd03220     1 IELENVSKSYPTYKGgssSLKKLgilgrkgeVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTL----LRLLAgiyppDS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 340 GGIRFEGKqldsltqqqVRPLrREMQVVFQdpfGSLSPRMCVsQIVGeglRIHKM-GTEAEQEQAIIAALKEVGLDPETR 418
Cdd:cd03220    77 GTVTVRGR---------VSSL-LGLGGGFN---PELTGRENI-YLNG---RLLGLsRKEIDEKIDEIIEFSELGDFIDLP 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 419 HRyphEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKALSHQLMVV 498
Cdd:cd03220   140 VK---TYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGK-TVILVSHDPSSIKRLCDRALVL 215


                  ....*....
gi 1834229548 499 KQGQVVEQG 507
Cdd:cd03220   216 EKGKIRFDG 224
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 6-237 2.10e-19

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 87.04  E-value: 2.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLpYPLARHPSGTIEYSGQNLLNLKEK 85
Cdd:cd03266     1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTT----LRML-AGLLEPDAGFATVDGFDVVKEPAE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRhirgnRIAMIFQEpmTSLNPLHSIEKQINEVLGIHkGLIGKVATKRTLELLEMVGIPE-PEKRLKalphELSGGQRQ 164
Cdd:cd03266    76 ARR-----RLGFVSDS--TGLYDRLTARENLEYFAGLY-GLKGDELTARLEELADRLGMEElLDRRVG----GFSTGMRQ 143

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALDVTVqLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIV 237
Cdd:cd03266   144 KVAIARALVHDPPVLLLDEPTTGLDVMA-TRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-234 2.43e-19

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 85.56  E-value: 2.43e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLavefvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpYPLARHPSGTIEYSGQNLlnlK 83
Cdd:cd03215     2 EPVLEVRGL--------SVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEAL-----FGLRPPASGEITLDGKPV---T 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRGNRIAMIFQEPM-TSLNPLHSIEKQInevlgihkgligkvatkrtlellemvgipepekrlkALPHELSGGQ 162
Cdd:cd03215    66 RRSPRDAIRAGIAYVPEDRKrEGLVLDLSVAENI------------------------------------ALSSLLSGGN 109

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 163 RQRVMIAMALANEPELLIADEPTTALDV-TVQlkILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd03215   110 QQKVVLARWLARDPRVLILDEPTRGVDVgAKA--EIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEG 180
cbiO PRK13645
energy-coupling factor transporter ATPase;
24-246 3.42e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 88.14  E-value: 3.42e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplarhpsgtIEYSGQNLL-------NLKE-KTIRHIRgNRI 95
Cdd:PRK13645   25 KALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLI-----------ISETGQTIVgdyaipaNLKKiKEVKRLR-KEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  96 AMIFQEPMTSLNPlHSIEKQIneVLG-IHKGLIGKVATKRTLELLEMVGIPEpeKRLKALPHELSGGQRQRVMIAMALAN 174
Cdd:PRK13645   93 GLVFQFPEYQLFQ-ETIEKDI--AFGpVNLGENKQEAYKKVPELLKLVQLPE--DYVKRSPFELSGGQKRRVALAGIIAM 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 175 EPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF 246
Cdd:PRK13645  168 DGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
290-526 4.97e-19

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 86.96  E-value: 4.97e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 290 GLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQVRplrREMQVVF 368
Cdd:PRK10253   16 GYGKYTV-----AENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTpAHGHVWLDGEHIQHYASKEVA---RRIGLLA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDpfGSLSPRMCVSQIVGEGLRIHK-MGTE--AEQEQAIIAALKEVGLDPETRHRYpHEFSGGQRQRIAIARALVLKPAL 445
Cdd:PRK10253   88 QN--ATTPGDITVQELVARGRYPHQpLFTRwrKEDEEAVTKAMQATGITHLADQSV-DTLSGGQRQRAWIAMVLAQETAI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGdaqsifaAPQHPYTQQLL 525
Cdd:PRK10253  165 MLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQG-------APKEIVTAELI 237


                  .
gi 1834229548 526 E 526
Cdd:PRK10253  238 E 238
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 299-509 5.13e-19

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 90.09  E-value: 5.13e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQLDSLTQQQVRPLRREMqvVFQDPfg 373
Cdd:COG3845    18 VVANDDVSLTVRPGEIHALLGENGAGKSTLmkilyGL----YQPDSGEILIDGKPVRIRSPRDAIALGIGM--VHQHF-- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SLSPRMCVSQ--IVG-EGLRIHKMGTEAEQEQaIIAALKEVGL--DPetrHRYPHEFSGGQRQRIAIARALVLKPALILL 448
Cdd:COG3845    90 MLVPNLTVAEniVLGlEPTKGGRLDRKAARAR-IRELSERYGLdvDP---DAKVEDLSVGEQQRVEILKALYRGARILIL 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 449 DEPTSALdrTVQ--RQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDA 509
Cdd:COG3845   166 DEPTAVL--TPQeaDELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDT 225
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
23-266 5.59e-19

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 86.61  E-value: 5.59e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLLNLKEKTIrhirGNRIAMIFQEP 102
Cdd:PRK11231   15 KRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLT-PQ----SGTVFLGDKPISMLSSRQL----ARRLALLPQHH 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNPlhSIEKQINEVLGIHKGLIGKVATK---RTLELLEMVGIPE-PEKRLKalphELSGGQRQRVMIAMALANEPEL 178
Cdd:PRK11231   86 LTPEGI--TVRELVAYGRSPWLSLWGRLSAEdnaRVNQAMEQTRINHlADRRLT----DLSGGQRQRAFLAMVLAQDTPV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 179 LIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFrapqhpyTRELL 258
Cdd:PRK11231  160 VLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVM-------TPGLL 231

                         250
                  ....*....|....*....
gi 1834229548 259 A----------AEP-SGTP 266
Cdd:PRK11231  232 RtvfdveaeihPEPvSGTP 250
cbiO PRK13642
energy-coupling factor transporter ATPase;
4-246 5.76e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 87.07  E-value: 5.76e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVvGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLlnlK 83
Cdd:PRK13642    2 NKILEVENLVFKYE-KESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLF-----EEFEGKVKIDGELL---T 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRgNRIAMIFQEPMtslNPLHSIEKQINEVLGI-HKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQ 162
Cdd:PRK13642   73 AENVWNLR-RKIGMVFQNPD---NQFVGATVEDDVAFGMeNQGIPREEMIKRVDEALLAVNMLDFKTRE---PARLSGGQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 163 RQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQASC 242
Cdd:PRK13642  146 KQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAP 224


                  ....
gi 1834229548 243 EQLF 246
Cdd:PRK13642  225 SELF 228
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-258 6.69e-19

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 86.74  E-value: 6.69e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAveFVVGERCqrVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLaRHPSGTIEYSGQNLL 80
Cdd:PRK11831    2 QSVANLVDMRGVS--FTRGNRC--IFDNISLTVPRGKITAIMGPSGIGKT----TLLRLIGGQI-APDHGEILFDGENIP 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRHIRgNRIAMIFQEP--MTSLNPLHSIEKQINEvlgiHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHEL 158
Cdd:PRK11831   73 AMSRSRLYTVR-KRMSMLFQSGalFTDMNVFDNVAYPLRE----HTQLPAPLLHSTVMMKLEAVGL---RGAAKLMPSEL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVE 238
Cdd:PRK11831  145 SGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVA 224

                         250       260
                  ....*....|....*....|
gi 1834229548 239 QASCEQLfRAPQHPYTRELL 258
Cdd:PRK11831  225 HGSAQAL-QANPDPRVRQFL 243
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 276-507 8.22e-19

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 84.52  E-value: 8.22e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 276 LTVEDLKVWFPIKKGLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLgLAIL--RLIGS--KGGIRFEGKQLDS 351
Cdd:cd03213     4 LSFRNLTVTVKSSPSKSGKQL-----LKNVSGKAKPGELTAIMGPSGAGKSTL-LNALagRRTGLgvSGEVLINGRPLDK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 352 LTqqqvrpLRREMQVVFQDP--FGSLSPRmcvsqivgEGLRIHkmgteaeqeqaiiAALKevGLdpetrhryphefSGGQ 429
Cdd:cd03213    78 RS------FRKIIGYVPQDDilHPTLTVR--------ETLMFA-------------AKLR--GL------------SGGE 116

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 430 RQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDL-AVVKALSHQLMVVKQGQVVEQG 507
Cdd:cd03213   117 RKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRL-ADTGRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
301-496 1.05e-18

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 84.21  E-value: 1.05e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTL--GLA-ILRLIGskGGIRFEGKQLDSLTQQQVR-----PLRremqvvfqdpf 372
Cdd:NF040873    7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLlkVLAgVLRPTS--GTVRRAGGARVAYVPQRSEvpdslPLT----------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 gslsprmcVSQIVGEGLRIHKMGT---EAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:NF040873   74 --------VRDLVAMGRWARRGLWrrlTRDDRAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEADLLLLD 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLM 496
Cdd:NF040873  145 EPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCVL 190
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 7-236 1.16e-18

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 87.97  E-value: 1.16e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLArhpsGTIEYSGQNLLNLKEKT 86
Cdd:PRK09536    4 IDVSDLSVEF--GD--TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLT-PTA----GTVLVAGDDVEALSARA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IrhirGNRIAMIFQEpmTSLNPLHSIEKQINEVLGIHKGLIGKV--ATKRTLE-LLEMVGIPEPEKRLKAlphELSGGQR 163
Cdd:PRK09536   75 A----SRRVASVPQD--TSLSFEFDVRQVVEMGRTPHRSRFDTWteTDRAAVErAMERTGVAQFADRPVT---SLSGGER 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQLKILELLkelqARL---GMALLLISHDLNLVKRIAHRVCVMQRGCI 236
Cdd:PRK09536  146 QRVLLARALAQATPVLLLDEPTASLDINHQVRTLELV----RRLvddGKTAVAAIHDLDLAARYCDELVLLADGRV 217
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
23-228 1.31e-18

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 83.82  E-value: 1.31e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhPSgtieySGqnllnlkekTIRHIRGNRIAMIFQE- 101
Cdd:NF040873    5 RPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLR------PT-----SG---------TVRRAGGARVAYVPQRs 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 ------PMTslnplhsiekqINEVLGI----HKGLIGKV---ATKRTLELLEMVGIPEPEKRlkALpHELSGGQRQRVMI 168
Cdd:NF040873   65 evpdslPLT-----------VRDLVAMgrwaRRGLWRRLtrdDRAAVDDALERVGLADLAGR--QL-GELSGGQRQRALL 130

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 169 AMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRV 228
Cdd:NF040873  131 AQGLAQEADLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189
cbiO PRK13649
energy-coupling factor transporter ATPase;
24-247 1.59e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 85.95  E-value: 1.59e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNL-KEKTIRHIRgNRIAMIFQEP 102
Cdd:PRK13649   21 RALFDVNLTIEDGSYTAFIGHTGSGKS----TIMQLLN-GLHVPTQGSVRVDDTLITSTsKNKDIKQIR-KKVGLVFQFP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNPlhsiEKQINEV------LGIHKgligKVATKRTLELLEMVGIPEP--EKRlkalPHELSGGQRQRVMIAMALAN 174
Cdd:PRK13649   95 ESQLFE----ETVLKDVafgpqnFGVSQ----EEAEALAREKLALVGISESlfEKN----PFELSGGQMRRVAIAGILAM 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 175 EPELLIADEPTTALDVTVQLKILELLKELQaRLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFR 247
Cdd:PRK13649  163 EPKILVLDEPTAGLDPKGRKELMTLFKKLH-QSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQ 234
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
6-248 1.90e-18

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 88.15  E-value: 1.90e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEfvvgercqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpYPLARHPSGTIEYSGqnllnlKEK 85
Cdd:COG1129   256 VLEVEGLSVG--------GVVRDVSFSVRAGEILGIAGLVGAGRTELARAL-----FGADPADSGEIRLDG------KPV 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIR---GNRIAMIfqeP----MTSLNPLHSIEKqiNEVLGI-----HKGLI-GKVATKRTLELLEMVGI--PEPEKR 150
Cdd:COG1129   317 RIRSPRdaiRAGIAYV---PedrkGEGLVLDLSIRE--NITLASldrlsRGGLLdRRRERALAEEYIKRLRIktPSPEQP 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 151 LKalphELSGGQRQRVMIAMALANEPELLIADEPTTALDV--------TVQlkilellkeLQARLGMALLLISHDLNLVK 222
Cdd:COG1129   392 VG----NLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVgakaeiyrLIR---------ELAAEGKAVIVISSELPELL 458

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1834229548 223 RIAHRVCVMQRGCIV-----EQASCEQLFRA 248
Cdd:COG1129   459 GLSDRILVMREGRIVgeldrEEATEEAIMAA 489
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 6-245 2.04e-18

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 88.63  E-value: 2.04e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDlaVEFVVGERC-QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLlpYplarHP-SGTIEYSGQNLLNLK 83
Cdd:TIGR00958 478 LIEFQD--VSFSYPNRPdVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNL--Y----QPtGGQVLLDGVPLVQYD 549

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRhirgNRIAMIFQEPMtslnpLHSIEKQINEVLGIHKGLIGKV-ATKRTLELLEMVGIPEPEKRLKALPH--ELSG 160
Cdd:TIGR00958 550 HHYLH----RQVALVGQEPV-----LFSGSVRENIAYGLTDTPDEEImAAAKAANAHDFIMEFPNGYDTEVGEKgsQLSG 620

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 161 GQRQRVMIAMALANEPELLIADEPTTALDVTVQlkilELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQA 240
Cdd:TIGR00958 621 GQKQRIAIARALVRKPRVLILDEATSALDAECE----QLLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMG 695


                  ....*
gi 1834229548 241 SCEQL 245
Cdd:TIGR00958 696 THKQL 700
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
305-517 2.56e-18

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 86.62  E-value: 2.56e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDsltqqQVRPLRREMQVVFQDPfgSLSPRM 379
Cdd:PRK11000   22 INLDIHEGEFVVFVGPSGCGKSTL----LRMIAglediTSGDLFIGEKRMN-----DVPPAERGVGMVFQSY--ALYPHL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 CVSQIVGEGLRIHKMG-TEAEQEQAIIAALKEVG--LDpetrhRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PRK11000   91 SVAENMSFGLKLAGAKkEEINQRVNQVAEVLQLAhlLD-----RKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLD 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 457 RTVQRQV-VELLRsLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:PRK11000  166 AALRVQMrIEISR-LHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPA 226
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 25-236 3.14e-18

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 83.67  E-value: 3.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLlpYPLARhpsGTIEYSGQNLLNLKEKTIRhirgNRIAMIFQEPMt 104
Cdd:cd03248    29 VLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENF--YQPQG---GQVLLDGKPISQYEHKYLH----SKVSLVGQEPV- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 slnpLHSIEKQINevlgIHKGLiGKVATKRTLELLEMVG----IPEPEKRLKALPHE----LSGGQRQRVMIAMALANEP 176
Cdd:cd03248    99 ----LFARSLQDN----IAYGL-QSCSFECVKEAAQKAHahsfISELASGYDTEVGEkgsqLSGGQKQRVAIARALIRNP 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 177 ELLIADEPTTALDVTVQLKILELLKELQARlgMALLLISHDLNLVKRiAHRVCVMQRGCI 236
Cdd:cd03248   170 QVLILDEATSALDAESEQQVQQALYDWPER--RTVLVIAHRLSTVER-ADQILVLDGGRI 226
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
299-510 4.30e-18

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 87.47  E-value: 4.30e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLIG--SKGGIRFEGKQLDSLTQQQVRPLRRE-MQVVFQDPfgSL 375
Cdd:PRK10535   21 VEVLKGISLDIYAGEMVAIVGASGSGKSTL-MNILGCLDkpTSGTYRVAGQDVATLDADALAQLRREhFGFIFQRY--HL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SPRMCVSQIVgEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:PRK10535   98 LSHLTAAQNV-EVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQ-PSQLSGGQQQRVSIARALMNGGQVILADEPTGAL 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQ 510
Cdd:PRK10535  176 DSHSGEEVMAILHQLRDRGH-TVIIVTHDPQVA-AQAERVIEIRDGEIVRNPPAQ 228
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 6-245 6.36e-18

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 87.08  E-value: 6.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNLLNLKEK 85
Cdd:TIGR02203 330 DVEFRNVTFRY--PGRDRPALDSISLVIEPGETVALVGRSGSGKS----TLVNLIPR-FYEPDSGQILLDGHDLADYTLA 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRhirgNRIAMIFQEpmtslnpLHSIEKQINEvlGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHE-------- 157
Cdd:TIGR02203 403 SLR----RQVALVSQD-------VVLFNDTIAN--NIAYGRTEQADRAEIERALAAAYAQDFVDKLPLGLDTpigengvl 469

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALDvtvqlkiLELLKELQARL-----GMALLLISHDLNLVKRiAHRVCVMQ 232
Cdd:TIGR02203 470 LSGGQRQRLAIARALLKDAPILILDEATSALD-------NESERLVQAALerlmqGRTTLVIAHRLSTIEK-ADRIVVMD 541

                         250
                  ....*....|...
gi 1834229548 233 RGCIVEQASCEQL 245
Cdd:TIGR02203 542 DGRIVERGTHNEL 554
PTZ00243 PTZ00243
ABC transporter; Provisional
 304-513 7.00e-18

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 87.53  E-value: 7.00e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  304 GINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTqqqVRPLRREMQVVFQDPF---GSlsprm 379
Cdd:PTZ00243  1328 GVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGeIRVNGREIGAYG---LRELRRQFSMIPQDPVlfdGT----- 1399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  380 cVSQIVGEGLrihkmgtEAEQEQaIIAALKEVGLdpetRHRYPHE--------------FSGGQRQRIAIARALVLK-PA 444
Cdd:PTZ00243  1400 -VRQNVDPFL-------EASSAE-VWAALELVGL----RERVASEsegidsrvleggsnYSVGQRQLMCMARALLKKgSG 1466

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548  445 LILLDEPTSALDRTVQRQVVELLRSLQSKYnlTYLFISHDLAVVkALSHQLMVVKQGQVVEQG-------DAQSIF 513
Cdd:PTZ00243  1467 FILMDEATANIDPALDRQIQATVMSAFSAY--TVITIAHRLHTV-AQYDKIIVMDHGAVAEMGsprelvmNRQSIF 1539
cbiO PRK13649
energy-coupling factor transporter ATPase;
300-513 7.40e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 84.03  E-value: 7.40e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILR--LIGSKGGIRFEGKQLDSLTQ-QQVRPLRREMQVVFQDPfgsls 376
Cdd:PRK13649   21 RALFDVNLTIEDGSYTAFIGHTGSGKSTI-MQLLNglHVPTQGSVRVDDTLITSTSKnKDIKQIRKKVGLVFQFP----- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prmcVSQIVGEG-LRIHKMG------TEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:PRK13649   95 ----ESQLFEETvLKDVAFGpqnfgvSQEEAEALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLD 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIF 513
Cdd:PRK13649  171 EPTAGLDPKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-237 9.56e-18

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 86.23  E-value: 9.56e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVefvVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarHPSGTIEYSGQNLLNLk 83
Cdd:COG3845   255 EVVLEVENLSV---RDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRP-----PASGSIRLDGEDITGL- 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 ekTIRHIRGNRIAMIFQEPM-TSLNPLHSIEKqiNEVLGIH-------KGLI-GKVATKRTLELLEMVGI--PEPEKRLK 152
Cdd:COG3845   326 --SPRERRRLGVAYIPEDRLgRGLVPDMSVAE--NLILGRYrrppfsrGGFLdRKAIRAFAEELIEEFDVrtPGPDTPAR 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 153 ALphelSGGQRQRVMIAMALANEPELLIADEPTTALDV----TVqlkilellkelQARL------GMALLLISHDLNLVK 222
Cdd:COG3845   402 SL----SGGNQQKVILARELSRDPKLLIAAQPTRGLDVgaieFI-----------HQRLlelrdaGAAVLLISEDLDEIL 466

                         250
                  ....*....|....*
gi 1834229548 223 RIAHRVCVMQRGCIV 237
Cdd:COG3845   467 ALSDRIAVMYEGRIV 481
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 28-515 1.06e-17

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 85.83  E-value: 1.06e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSvtahSILRLLP--YPLarhPSGTIEYSGQNllnlkektiRHIRGNR------IAMIF 99
Cdd:PRK10762   22 GAALNVYPGRVMALVGENGAGKS----TMMKVLTgiYTR---DAGSILYLGKE---------VTFNGPKssqeagIGIIH 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 100 QEpmtsLN--PLHSIEKQIneVLGIH-KGLIGKVATKRTLE----LLEMVGIPEPEKRLKAlphELSGGQRQRVMIAMAL 172
Cdd:PRK10762   86 QE----LNliPQLTIAENI--FLGREfVNRFGRIDWKKMYAeadkLLARLNLRFSSDKLVG---ELSIGEQQMVEIAKVL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 173 ANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRG-----CIVEQASCEQLF- 246
Cdd:PRK10762  157 SFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGqfiaeREVADLTEDSLIe 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 247 ----RAPQHPYTRelLAAEPsgtpatnvvGPPMLTVEDLkvwfpikKGllkktvdyvKAVDGINFSLPQGQTLGIVGESG 322
Cdd:PRK10762  236 mmvgRKLEDQYPR--LDKAP---------GEVRLKVDNL-------SG---------PGVNDVSFTLRKGEILGVSGLMG 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 323 SGKSTLGLAIL-RLIGSKGGIRFEGKQLDSLTQQQvrPLRREMQVVFQDPFG-------SLSPRMCVS---QIVGEGLRI 391
Cdd:PRK10762  289 AGRTELMKVLYgALPRTSGYVTLDGHEVVTRSPQD--GLANGIVYISEDRKRdglvlgmSVKENMSLTalrYFSRAGGSL 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 392 HKmgteAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQ 471
Cdd:PRK10762  367 KH----ADEQQAVSDFIRLFNIKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFK 442

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 1834229548 472 SKyNLTYLFISHDLAVVKALSHQLMVVKQGQV-----VEQGDAQSIFAA 515
Cdd:PRK10762  443 AE-GLSIILVSSEMPEVLGMSDRILVMHEGRIsgeftREQATQEKLMAA 490
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
292-510 1.20e-17

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 82.75  E-value: 1.20e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaILRLIGSKGGIRFEGKQLDSLTQ---------QQVRPLRR 362
Cdd:PRK09984   10 LAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTL---LRHLSGLITGDKSAGSHIELLGRtvqregrlaRDIRKSRA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 363 EMQVVFQDpfGSLSPRMCVSqivgEGLRIHKMGT-----------EAEQEQAIIAALKEVGLdPETRHRYPHEFSGGQRQ 431
Cdd:PRK09984   87 NTGYIFQQ--FNLVNRLSVL----ENVLIGALGStpfwrtcfswfTREQKQRALQALTRVGM-VHFAHQRVSTLSGGQQQ 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 432 RIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQ 510
Cdd:PRK09984  160 RVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQ 238
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
24-504 1.20e-17

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 85.73  E-value: 1.20e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplarhpSGtiEY---SGQNLLNLKEKTIRHIR---GNRIAM 97
Cdd:PRK11288   18 KALDDISFDCRAGQVHALMGENGAGKS----TLLKIL--------SG--NYqpdAGSILIDGQEMRFASTTaalAAGVAI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  98 IFQEpmtslnpLHSI-EKQINEVLGI----HK-GLI-GKVATKRTLELLEMVGIP-EPEKRLKalphELSGGQRQRVMIA 169
Cdd:PRK11288   84 IYQE-------LHLVpEMTVAENLYLgqlpHKgGIVnRRLLNYEAREQLEHLGVDiDPDTPLK----YLSIGQRQMVEIA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 170 MALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQ-ASCEQLfra 248
Cdd:PRK11288  153 KALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVATfDDMAQV--- 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 249 pqhpyTRELLAAEPSGTPATNV-------VGPPMLTVEDLKvwfpiKKGLlkktvdyvkaVDGINFSLPQGQTLGIVGES 321
Cdd:PRK11288  229 -----DRDQLVQAMVGREIGDIygyrprpLGEVRLRLDGLK-----GPGL----------REPISFSVRAGEIVGLFGLV 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 322 GSGKSTLglaiLRLI-----GSKGGIRFEGKQLD-SLTQQQVR------PLRREMQVVFqdPFGSLSPRMCVS---QIVG 386
Cdd:PRK11288  289 GAGRSEL----MKLLygatrRTAGQVYLDGKPIDiRSPRDAIRagimlcPEDRKAEGII--PVHSVADNINISarrHHLR 362

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 387 EGLRIHKmGTEAEQEQAIIAALKEVGLDPETRHRYpheFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVEL 466
Cdd:PRK11288  363 AGCLINN-RWEAENADRFIRSLNIKTPSREQLIMN---LSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNV 438

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1834229548 467 LRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:PRK11288  439 IYEL-AAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
307-529 1.33e-17

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 83.01  E-value: 1.33e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 307 FSLPQGQTLGIVGESGSGKSTLGLAILrligskGGIRFEGKQLDSLTQQQVRPLRREM-QVVFQDPFGSLSPRMCVSQIV 385
Cdd:PRK15056   28 FTVPGGSIAALVGVNGSGKSTLFKALM------GFVRLASGKISILGQPTRQALQKNLvAYVPQSEEVDWSFPVLVEDVV 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 386 GEGlRIHKMG----TEAEQEQAIIAALKEVGLdPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQR 461
Cdd:PRK15056  102 MMG-RYGHMGwlrrAKKRDRQIVTAALARVDM-VEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEA 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 462 QVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKqGQVVEQGDAQSIFAAPQhpytqqlLEAAF 529
Cdd:PRK15056  180 RIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYTVMVK-GTVLASGPTETTFTAEN-------LELAF 238
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
7-217 1.46e-17

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 82.60  E-value: 1.46e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLArhPSgtieySGQNLLNlkEKT 86
Cdd:COG4525     4 LTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKT----TLLNLIAGFLA--PS-----SGEITLD--GVP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGNRiAMIFQEpmTSLNP-LHSIEkqiNEVLGIH-KGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQ 164
Cdd:COG4525    71 VTGPGADR-GVVFQK--DALLPwLNVLD---NVAFGLRlRGVPKAERRARAEELLALVGLADFARRR---IWQLSGGMRQ 141

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHD 217
Cdd:COG4525   142 RVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHS 194
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 302-502 1.87e-17

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 79.89  E-value: 1.87e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIrfegkqldsltqqqVRPLRREMQVVFQDPFgsls 376
Cdd:cd03223    17 LKDLSFEIKPGDRLLITGPSGTGKSSL----FRALAglwpwGSGRI--------------GMPEGEDLLFLPQRPY---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prMCVsqivgeglrihkmGTEAEQeqaIIaalkevgldpetrhrYP--HEFSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:cd03223    75 --LPL-------------GTLREQ---LI---------------YPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSA 121

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1834229548 455 LDRTVQRQVVELLRSLQSkynlTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:cd03223   122 LDEESEDRLYQLLKELGI----TVISVGHRPSLWKFHDRVLDLDGEGG 165
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 25-259 2.42e-17

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 81.03  E-value: 2.42e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEktirHIRGNR-IA------M 97
Cdd:TIGR03410  15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVK-----SGSIRLDGEDITKLPP----HERARAgIAyvpqgrE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  98 IFqepmtslnPLHSIEKQINEVLGihkgLIGKVATKRTLELLEMVGIpepekrLKALPH----ELSGGQRQRVMIAMALA 173
Cdd:TIGR03410  86 IF--------PRLTVEENLLTGLA----ALPRRSRKIPDEIYELFPV------LKEMLGrrggDLSGGQQQQLAIARALV 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 174 NEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLfrapQHPY 253
Cdd:TIGR03410 148 TRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL----DEDK 223


                  ....*.
gi 1834229548 254 TRELLA 259
Cdd:TIGR03410 224 VRRYLA 229
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 30-242 2.56e-17

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 80.68  E-value: 2.56e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  30 SFDIKRGETLALVGESGSGKSvTAHSILRLLPYPLarhpSGTIEYSGQNLLNLKEKTirhirgNRIAMIFQEPmtslNPL 109
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKS-TLLNLIAGFIEPA----SGSIKVNDQSHTGLAPYQ------RPVSMLFQEN----NLF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 110 HSIEKQINEVLGIHKGL-IGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLIADEPTTAL 188
Cdd:TIGR01277  83 AHLTVRQNIGLGLHPGLkLNAEQQEKVVDAAQQVGIADYLDRL---PEQLSGGQRQRVALARCLVRPNPILLLDEPFSAL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 189 DVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASC 242
Cdd:TIGR01277 160 DPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSDC 213
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 7-238 2.65e-17

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 80.26  E-value: 2.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEfvVGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpyplARHPS-----GTIEYSGQNLLN 81
Cdd:cd03217     1 LEIKDLHVS--VGGK--EILKGVNLTIKKGEVHALMGPNGSGKSTLAKTI--------MGHPKyevteGEILFKGEDITD 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LkEKTIRHIRGnrIAMIFQEPMtslnplhsiekqinEVLGIhkgligkvatkRTLELLEMVGIpepekrlkalphELSGG 161
Cdd:cd03217    69 L-PPEERARLG--IFLAFQYPP--------------EIPGV-----------KNADFLRYVNE------------GFSGG 108

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALDVtVQLKILELLKELQARLGMALLLISHDLNLVKRI-AHRVCVMQRGCIVE 238
Cdd:cd03217   109 EKKRNEILQLLLLEPDLAILDEPDSGLDI-DALRLVAEVINKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVK 185
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 2-261 3.17e-17

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 84.90  E-value: 3.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYplarhpSGTIEYSGQNLLN 81
Cdd:PRK11174  345 NDPVTIEAEDLEILSPDG---KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPY------QGSLKINGIELRE 415

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHirgnRIAMIFQEPMTslnPLHSIEKQInevlgihkgLIGKV-ATKRTLE-LLEMVGIPEPEKRL-KALPHE- 157
Cdd:PRK11174  416 LDPESWRK----HLSWVGQNPQL---PHGTLRDNV---------LLGNPdASDEQLQqALENAWVSEFLPLLpQGLDTPi 479

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 ------LSGGQRQRVMIAMALANEPELLIADEPTTALDvtVQLKILELLKELQARLGMALLLISHDLNLVKRIaHRVCVM 231
Cdd:PRK11174  480 gdqaagLSVGQAQRLALARALLQPCQLLLLDEPTASLD--AHSEQLVMQALNAASRRQTTLMVTHQLEDLAQW-DQIWVM 556

                         250       260       270
                  ....*....|....*....|....*....|
gi 1834229548 232 QRGCIVEQASCEQLfrAPQHPYTRELLAAE 261
Cdd:PRK11174  557 QDGQIVQQGDYAEL--SQAGGLFATLLAHR 584
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 25-241 3.20e-17

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 80.62  E-value: 3.20e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYplarhPSGTIEYSGQNLLNLKEKTIRhirgNRIAMIFQEPMT 104
Cdd:cd03244    19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVEL-----SSGSILIDGVDISKIGLHDLR----SRISIIPQDPVL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 -------SLNPL--HSiEKQINEVLgihkgligkvatkRTLELLEMVgipepEKRLKALPHE-------LSGGQRQRVMI 168
Cdd:cd03244    90 fsgtirsNLDPFgeYS-DEELWQAL-------------ERVGLKEFV-----ESLPGGLDTVveeggenLSVGQRQLLCL 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 169 AMALANEPELLIADEPTTALDvtVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQAS 241
Cdd:cd03244   151 ARALLRKSKILVLDEATASVD--PETDALIQKTIREAFKDCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDS 220
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 4-245 3.98e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 81.71  E-value: 3.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSVTahsILRLLPYPLARHpsGTIEYSGQNLlnlK 83
Cdd:PRK13647    2 DNIIEVEDLHFRYKDG---TKALKGLSLSIPEGSKTALLGPNGAGKSTL---LLHLNGIYLPQR--GRVKVMGREV---N 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRgNRIAMIFQEPMtslNPLHSIEKQINEVLG-IHKGLIGKVATKRTLELLEMVGIPEpeKRLKAlPHELSGGQ 162
Cdd:PRK13647   71 AENEKWVR-SKVGLVFQDPD---DQVFSSTVWDDVAFGpVNMGLDKDEVERRVEEALKAVRMWD--FRDKP-PYHLSYGQ 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 163 RQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASC 242
Cdd:PRK13647  144 KKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK 222


                  ...
gi 1834229548 243 EQL 245
Cdd:PRK13647  223 SLL 225
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
302-515 4.23e-17

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 82.16  E-value: 4.23e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKST-----LGLAIlrliGSKGGIRFEGKQLdsltQQQVRPLRREMQVVFQdpFGSLS 376
Cdd:PRK13537   23 VDGLSFHVQRGECFGLLGPNGAGKTTtlrmlLGLTH----PDAGSISLCGEPV----PSRARHARQRVGVVPQ--FDNLD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 PRMCVSqivgEGLRI--HKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:PRK13537   93 PDFTVR----ENLLVfgRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTG 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 455 LDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:PRK13537  169 LDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES 228
cbiO PRK13643
energy-coupling factor transporter ATPase;
24-247 4.98e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 81.70  E-value: 4.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHPSGTIEYSGQNllnlKEKTIRHIRgNRIAMIFQEPM 103
Cdd:PRK13643   20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTS----KQKEIKPVR-KKVGVVFQFPE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 TSLNPlHSIEKQIN---EVLGIHKGLIGKVATKRtlelLEMVGIPEpeKRLKALPHELSGGQRQRVMIAMALANEPELLI 180
Cdd:PRK13643   95 SQLFE-ETVLKDVAfgpQNFGIPKEKAEKIAAEK----LEMVGLAD--EFWEKSPFELSGGQMRRVAIAGILAMEPEVLV 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 181 ADEPTTALDVTVQLKILELLKELQaRLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFR 247
Cdd:PRK13643  168 LDEPTAGLDPKARIEMMQLFESIH-QSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQ 233
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
 25-245 6.30e-17

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 84.22  E-value: 6.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKektiRHIRGNRIAMIFQ---- 100
Cdd:TIGR03796 494 LIENFSLTLQPGQRVALVGGSGSGKS----TIAKLVA-GLYQPWSGEILFDGIPREEIP----REVLANSVAMVDQdifl 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 101 ------EPMTSLNPlhSI-EKQINEVL---GIHkGLIGKVATKRTLELLEMVGipepekrlkalphELSGGQRQRVMIAM 170
Cdd:TIGR03796 565 fegtvrDNLTLWDP--TIpDADLVRACkdaAIH-DVITSRPGGYDAELAEGGA-------------NLSGGQRQRLEIAR 628

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 171 ALANEPELLIADEPTTALDVTVQLKILELLkelqARLGMALLLISHDLNLVkRIAHRVCVMQRGCIVEQASCEQL 245
Cdd:TIGR03796 629 ALVRNPSILILDEATSALDPETEKIIDDNL----RRRGCTCIIVAHRLSTI-RDCDEIIVLERGKVVQRGTHEEL 698
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
302-512 6.71e-17

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 82.19  E-value: 6.71e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSltqqQVRPLRREMQVVFQdpFGSLSPRMC 380
Cdd:PRK13536   57 VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSpDAGKITVLGVPVPA----RARLARARIGVVPQ--FDNLDLEFT 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQ---IVGEGLRIHkmgteAEQEQAIIAALKEVG-LDPETRHRYPhEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PRK13536  131 VREnllVFGRYFGMS-----TREIEAVIPSLLEFArLESKADARVS-DLSGGMKRRLTLARALINDPQLLILDEPTTGLD 204

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 457 RTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:PRK13536  205 PHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
305-515 7.18e-17

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 83.61  E-value: 7.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTlgLAILrLIG----SKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQDPFgSLSPRMC 380
Cdd:PRK10790  360 INLSVPSRGFVALVGHTGSGKST--LASL-LMGyyplTEGEIRLDGRPLSSLSHSV---LRQGVAMVQQDPV-VLADTFL 432

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 VSQIVGEGLRihkmgteaeqEQAIIAALKEVGLD------PETRHRYPHE----FSGGQRQRIAIARALVLKPALILLDE 450
Cdd:PRK10790  433 ANVTLGRDIS----------EEQVWQALETVQLAelarslPDGLYTPLGEqgnnLSVGQKQLLALARVLVQTPQILILDE 502

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 451 PTSALDRTVQRQVVELLRSLQSKynLTYLFISHDLA-VVKAlsHQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:PRK10790  503 ATANIDSGTEQAIQQALAAVREH--TTLVVIAHRLStIVEA--DTILVLHRGQAVEQGTHQQLLAA 564
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 293-470 1.05e-16

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 79.24  E-value: 1.05e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 293 KKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSK----GGIRFEGKQLDsltqqqvrplRREMQ--V 366
Cdd:cd03234    14 KNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttsGQILFNGQPRK----------PDQFQkcV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPFGSLSPRMCVSQIV--GEGLRIHKMGTEAE-QEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKP 443
Cdd:cd03234    84 AYVRQDDILLPGLTVRETLtyTAILRLPRKSSDAIrKKRVEDVLLRDLALTR-IGGNLVKGISGGERRRVSIAVQLLWDP 162

                         170       180
                  ....*....|....*....|....*..
gi 1834229548 444 ALILLDEPTSALDRTVQRQVVELLRSL 470
Cdd:cd03234   163 KVLILDEPTSGLDSFTALNLVSTLSQL 189
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 292-516 1.49e-16

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 79.12  E-value: 1.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTQQQvrplRREMQVVF-- 368
Cdd:cd03218     6 LSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKpDSGKILLDGQDITKLPMHK----RARLGIGYlp 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDPfgSLSPRMCVSQIVGEGLRIHKMgTEAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALILL 448
Cdd:cd03218    82 QEA--SIFRKLTVEENILAVLEIRGL-SKKEREEKLEELLEEFHITH-LRKSKASSLSGGERRRVEIARALATNPKFLLL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 449 DEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:cd03218   158 DEPFAGVDPIAVQDIQKIIKILKDR-GIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANE 224
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 25-231 1.72e-16

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 82.33  E-value: 1.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhP-SGTIEYSGQNLLNLKEKTIRhirgNRIAMIFQEPm 103
Cdd:TIGR02857 337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVD------PtEGSIAVNGVPLADADADSWR----DQIAWVPQHP- 405

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 tslnplHSIEKQINEVLGIHKGLIGKVATKRTLE---LLEMV-GIPEP-EKRLKALPHELSGGQRQRVMIAMALANEPEL 178
Cdd:TIGR02857 406 ------FLFAGTIAENIRLARPDASDAEIREALEragLDEFVaALPQGlDTPIGEGGAGLSGGQAQRLALARAFLRDAPL 479

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 179 LIADEPTTALDvtVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVM 231
Cdd:TIGR02857 480 LLLDEPTAHLD--AETEAEVLEALRALAQGRTVLLVTHRLALAAL-ADRIVVL 529
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-239 2.08e-16

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 81.15  E-value: 2.08e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLL 80
Cdd:PRK09452    9 SSLSPLVELRGISKSF--DGKE--VISNLDLTINNGEFLTLLGPSGCGKT----TVLRLIA-GFETPDSGRIMLDGQDIT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NL-KEKtiRHIRgnriaMIFQEpmTSLNPLHSIEKQINEVLGIHKGLIGKVATkRTLELLEMVGIPEPEKRLkalPHELS 159
Cdd:PRK09452   80 HVpAEN--RHVN-----TVFQS--YALFPHMTVFENVAFGLRMQKTPAAEITP-RVMEALRMVQLEEFAQRK---PHQLS 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIvEQ 239
Cdd:PRK09452  147 GGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRI-EQ 225
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
305-516 2.21e-16

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 79.06  E-value: 2.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSLtqqQVRPLRREMQVVFQdpfgSLSPR- 378
Cdd:PRK10575   30 LSLTFPAGKVTGLIGHNGSGKSTL----LKMLGrhqppSEGEILLDAQPLESW---SSKAFARKVAYLPQ----QLPAAe 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 -MCVSQIVGEGlRIHKMGT----EAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:PRK10575   99 gMTVRELVAIG-RYPWHGAlgrfGAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTS 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 454 ALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:PRK10575  177 ALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGE 239
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 4-190 2.27e-16

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 78.97  E-value: 2.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDlaVEFVVGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpypLARHPSGtieySGQNLLNLK 83
Cdd:COG1119     1 DPLLELRN--VTVRRGGK--TILDDISWTVKPGEHWAILGPNGAGKS----TLLSLI---TGDLPPT----YGNDVRLFG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EK----TIRHIRgNRIAMIFQEPMTSLNPLHSIEkqinEV--------LGIHKGlIGKVATKRTLELLEMVGIpepEKRL 151
Cdd:COG1119    66 ERrggeDVWELR-KRIGLVSPALQLRFPRDETVL----DVvlsgffdsIGLYRE-PTDEQRERARELLELLGL---AHLA 136

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1834229548 152 KALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDV 190
Cdd:COG1119   137 DRPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDL 175
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 7-218 2.27e-16

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 82.02  E-value: 2.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvgERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLLNLKEKT 86
Cdd:TIGR02868 335 LELRDLSAGY---PGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLD-PL----QGEVTLDGVPVSSLDQDE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRhirgNRIAMIFQEPmtslnplHSIEKQINEVLGIHKGligKVATKRTLELLEMVGIPEPekrLKALPH---------- 156
Cdd:TIGR02868 407 VR----RRVSVCAQDA-------HLFDTTVRENLRLARP---DATDEELWAALERVGLADW---LRALPDgldtvlgegg 469

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 157 -ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVqlKILELLKELQARLGMALLLISHDL 218
Cdd:TIGR02868 470 aRLSGGERQRLALARALLADAPILLLDEPTEHLDAET--ADELLEDLLAALSGRTVVLITHHL 530
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 7-247 2.38e-16

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 80.13  E-value: 2.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGERCQ-----------------RVVEGVSFDIKRGETLALVGESGSGKSVTahsiLRLLPYPLarHP- 68
Cdd:COG4586     2 IEVENLSKTYRVYEKEPglkgalkglfrreyrevEAVDDISFTIEPGEIVGFIGPNGAGKSTT----IKMLTGIL--VPt 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  69 SGTIEYSGqnlLNLKEKTIRHIRgnRIAMIF---QEPMTSLNPLHSIEkqineVLG-IHKglIGKVATKRTL-ELLEMVG 143
Cdd:COG4586    76 SGEVRVLG---YVPFKRRKEFAR--RIGVVFgqrSQLWWDLPAIDSFR-----LLKaIYR--IPDAEYKKRLdELVELLD 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 144 IpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKR 223
Cdd:COG4586   144 L---GELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEA 220

                         250       260
                  ....*....|....*....|....
gi 1834229548 224 IAHRVCVMQRGCIVEQASCEQLFR 247
Cdd:COG4586   221 LCDRVIVIDHGRIIYDGSLEELKE 244
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 8-238 2.72e-16

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 78.57  E-value: 2.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRDLAVEfvVGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpyplARHP-----SGTIEYSGQNLLNL 82
Cdd:COG0396     2 EIKNLHVS--VEGK--EILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVL--------MGHPkyevtSGSILLDGEDILEL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 kEKTIRHIRGnrIAMIFQEP-----MTSLNPLHSIEKQINEvlgihKGLIGKVATKRTLELLEMVGIPEpekrlKALPHE 157
Cdd:COG0396    70 -SPDERARAG--IFLAFQYPveipgVSVSNFLRTALNARRG-----EELSAREFLKLLKEKMKELGLDE-----DFLDRY 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 L----SGGQRQRVMIAMALANEPELLIADEPTTALDV--------TVQLKILEllkelqarlGMALLLISHD---LNLVK 222
Cdd:COG0396   137 VnegfSGGEKKRNEILQMLLLEPKLAILDETDSGLDIdalrivaeGVNKLRSP---------DRGILIITHYqriLDYIK 207

                         250
                  ....*....|....*.
gi 1834229548 223 riAHRVCVMQRGCIVE 238
Cdd:COG0396   208 --PDFVHVLVDGRIVK 221
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 23-189 6.65e-16

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 76.46  E-value: 6.65e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGeTLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEKtirhIRGnRIAMIFQEP 102
Cdd:cd03264    13 KRALDGVSLTLGPG-MYGLLGPNGAGKT----TLMRILA-TLTPPSSGTIRIDGQDVLKQPQK----LRR-RIGYLPQEF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSlnPLHSIEKQINeVLGIHKGLIGKVATKRTLELLEMVGIPEpekRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03264    82 GVY--PNFTVREFLD-YIAWLKGIPSKEVKARVDEVLELVNLGD---RAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155


                  ....*..
gi 1834229548 183 EPTTALD 189
Cdd:cd03264   156 EPTAGLD 162
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 7-189 6.71e-16

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 77.82  E-value: 6.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVG---ERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLP--YPLArhpSGTIEYSGQNLLN 81
Cdd:COG1101     2 LELKNLSKTFNPGtvnEK--RALDGLNLTIEEGDFVTVIGSNGAGKS----TLLNAIAgsLPPD---SGSILIDGKDVTK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEktirHIRGNRIAMIFQEPMTSLNPLHSIE------KQINEVLGIHKGLIGKVAT--KRTLELLEMvGIpepEKRLKA 153
Cdd:COG1101    73 LPE----YKRAKYIGRVFQDPMMGTAPSMTIEenlalaYRRGKRRGLRRGLTKKRRElfRELLATLGL-GL---ENRLDT 144

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1834229548 154 LPHELSGGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:COG1101   145 KVGLLSGGQRQALSLLMATLTKPKLLLLDEHTAALD 180
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
299-505 7.27e-16

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 80.34  E-value: 7.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILR--LIGSKGGIRFEGKQL------DSLTqQQVRPLRREMQVVfqd 370
Cdd:PRK11288   17 VKALDDISFDCRAGQVHALMGENGAGKSTL-LKILSgnYQPDAGSILIDGQEMrfasttAALA-AGVAIIYQELHLV--- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 371 pfgslsPRMCVSQIVGEGLRIHKMG--TEAEQEQAIIAALKEVG--LDPETRHRYpheFSGGQRQRIAIARALVLKPALI 446
Cdd:PRK11288   92 ------PEMTVAENLYLGQLPHKGGivNRRLLNYEAREQLEHLGvdIDPDTPLKY---LSIGQRQMVEIAKALARNARVI 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVE 505
Cdd:PRK11288  163 AFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 272-503 7.71e-16

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 75.55  E-value: 7.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 272 GPPMLTVEDLKVWfpikkgllkktvdyvKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLD 350
Cdd:cd03215     1 GEPVLEVRGLSVK---------------GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGeITLDGKPVT 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 351 SLTQQQVRplRREMQVVFQDPFGslsprmcvsqivgEGLrIHKMGTEaeqEQAIIAALkevgldpetrhrypheFSGGQR 430
Cdd:cd03215    66 RRSPRDAI--RAGIAYVPEDRKR-------------EGL-VLDLSVA---ENIALSSL----------------LSGGNQ 110

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 431 QRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:cd03215   111 QKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 276-509 7.79e-16

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 76.03  E-value: 7.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 276 LTVEDLKVwfpikkgllkkTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAIL---RLIGSKGGIRFEGKQLDSL 352
Cdd:cd03217     1 LEIKDLHV-----------SVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMghpKYEVTEGEILFKGEDITDL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 353 TQQQvRPlRREMQVVFQDPfgslsPRMcvsqivgEGLRIHKMgteaeqeqaiiaaLKEVGLDpetrhrypheFSGGQRQR 432
Cdd:cd03217    70 PPEE-RA-RLGIFLAFQYP-----PEI-------PGVKNADF-------------LRYVNEG----------FSGGEKKR 112

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 433 IAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHD---LAVVKALSHQLMVvkQGQVVEQGDA 509
Cdd:cd03217   113 NEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREE-GKSVLIITHYqrlLDYIKPDRVHVLY--DGRIVKSGDK 189
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 303-499 8.19e-16

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 76.54  E-value: 8.19e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLGLAILRLI-GSKGGIRFEgkqldsltqqqvrplrremqvVFQDPFGSLSPrmcv 381
Cdd:COG2401    47 RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkGTPVAGCVD---------------------VPDNQFGREAS---- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 382 sqiVGEGLRIHKMGTEAeqeqaiIAALKEVGL-DPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQ 460
Cdd:COG2401   102 ---LIDAIGRKGDFKDA------VELLNAVGLsDAVLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTA 172

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1834229548 461 RQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVK 499
Cdd:COG2401   173 KRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIFV 211
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
 276-508 8.34e-16

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 76.92  E-value: 8.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 276 LTVEDLKVwfpikkgllkkTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAIL---RLIGSKGGIRFEGKQLDSL 352
Cdd:TIGR01978   1 LKIKDLHV-----------SVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAghpSYEVTSGTILFKGQDLLEL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 353 TQQQvRPlRREMQVVFQDPfgSLSPRMCVSQIVGEGLRIHkmgTEAEQEQAIIA---------ALKEVGLDPETRHRYPH 423
Cdd:TIGR01978  70 EPDE-RA-RAGLFLAFQYP--EEIPGVSNLEFLRSALNAR---RSARGEEPLDLldfekllkeKLALLDMDEEFLNRSVN 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 424 E-FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKALS----HQLMvv 498
Cdd:TIGR01978 143 EgFSGGEKKRNEILQMALLEPKLAILDEIDSGLDIDALKIVAEGINRLREPDR-SFLIITHYQRLLNYIKpdyvHVLL-- 219

                         250
                  ....*....|
gi 1834229548 499 kQGQVVEQGD 508
Cdd:TIGR01978 220 -DGRIVKSGD 228
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 7-236 1.03e-15

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 74.95  E-value: 1.03e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAveFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQnllnlkekt 86
Cdd:cd03246     1 LEVENVS--FRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLR-PT----SGRVRLDGA--------- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 irhirgnriamifqepmtslnPLHSIEkqinevLGIHKGLIGKVAtkRTLELLE---MVGIpepekrlkalpheLSGGQR 163
Cdd:cd03246    65 ---------------------DISQWD------PNELGDHVGYLP--QDDELFSgsiAENI-------------LSGGQR 102

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRiAHRVCVMQRGCI 236
Cdd:cd03246   103 QRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAA-GATRIVIAHRPETLAS-ADRILVLEDGRV 173
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 1-246 1.08e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 77.10  E-value: 1.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLL 80
Cdd:PRK13648    2 EDKNSIIVFKN--VSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVK-----SGEIFYNNQAIT 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRhirgNRIAMIFQEPMTSLnpLHSIEKqINEVLGI------HKGLIGKVatKRTLELLEMVGIPEPEkrlkal 154
Cdd:PRK13648   75 DDNFEKLR----KHIGIVFQNPDNQF--VGSIVK-YDVAFGLenhavpYDEMHRRV--SEALKQVDMLERADYE------ 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHrVCVMQRG 234
Cdd:PRK13648  140 PNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADH-VIVMNKG 218

                         250
                  ....*....|..
gi 1834229548 235 CIVEQASCEQLF 246
Cdd:PRK13648  219 TVYKEGTPTEIF 230
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 304-468 1.12e-15

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 75.68  E-value: 1.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDSltqqqvrPLRREmQVVFQDPFGSLSPR 378
Cdd:PRK13539   20 GLSFTLAAGEALVLTGPNGSGKTTL----LRLIAgllppAAGTIKLDGGDIDD-------PDVAE-ACHYLGHRNAMKPA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSQIVGEGLRIHkmGTEaeqEQAIIAALKEVGLDPETrHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:PRK13539   88 LTVAENLEFWAAFL--GGE---ELDIAAALEAVGLAPLA-HLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAA 161

                         170
                  ....*....|
gi 1834229548 459 VQRQVVELLR 468
Cdd:PRK13539  162 AVALFAELIR 171
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 23-219 1.13e-15

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 75.98  E-value: 1.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVtahsilrLLPYpLARHPSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEP 102
Cdd:COG4136    14 RPLLAPLSLTVAPGEILTLMGPSGSGKST-------LLAA-IAGTLSPAFSASGEVLLNGRRLTALPAEQRRIGILFQDD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MtsLNPLHSIEKqiNEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:COG4136    86 L--LFPHLSVGE--NLAFALPPTIGRAQRRARVEQALEEAGLAGFADRD---PATLSGGQRARVALLRALLAEPRALLLD 158

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1834229548 183 EPTTALDVTVQLKILELLKELQARLGMALLLISHDLN 219
Cdd:COG4136   159 EPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEE 195
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 3-241 1.41e-15

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 75.53  E-value: 1.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   3 QDNLIEVRDLAVEFvvGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYplarhPSGTIEYSGQNLLNL 82
Cdd:cd03369     3 EHGEIEVENLSVRY--APDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEA-----EEGKIEIDGIDISTI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 KEKTIRhirgNRIAMIFQEPM-------TSLNPL-HSIEKQINEVLGIHKGligkvatkrtlellemvgipepekrlkal 154
Cdd:cd03369    76 PLEDLR----SSLTIIPQDPTlfsgtirSNLDPFdEYSDEEIYGALRVSEG----------------------------- 122

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQArlGMALLLISHDLNLVKRIAhRVCVMQRG 234
Cdd:cd03369   123 GLNLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIREEFT--NSTILTIAHRLRTIIDYD-KILVMDAG 199


                  ....*..
gi 1834229548 235 CIVEQAS 241
Cdd:cd03369   200 EVKEYDH 206
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 7-237 1.51e-15

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 75.70  E-value: 1.51e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:cd03245     3 IEFRN--VSFSYPNQEIPALDNVSLTIRAGEKVAIIGRVGSGKS----TLLKLL-AGLYKPTSGSVLLDGTDIRQLDPAD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHirgnRIAMIFQEPM----------TSLNPLHSIEK--QINEVLGIHKgLIGKvaTKRTLELleMVGipepEKrlkal 154
Cdd:cd03245    76 LRR----NIGYVPQDVTlfygtlrdniTLGAPLADDERilRAAELAGVTD-FVNK--HPNGLDL--QIG----ER----- 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 PHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQlkILELLKELQARLGMALLLISHDLNLVKrIAHRVCVMQRG 234
Cdd:cd03245   138 GRGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSE--ERLKERLRQLLGDKTLIIITHRPSLLD-LVDRIIVMDSG 214


                  ...
gi 1834229548 235 CIV 237
Cdd:cd03245   215 RIV 217
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
25-238 1.79e-15

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 77.56  E-value: 1.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLArhpsGTIEYSGQNLlnlkEKTIRHIRGnRIAMIFQepMT 104
Cdd:PRK13536   56 VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTS-PDA----GKITVLGVPV----PARARLARA-RIGVVPQ--FD 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 SLNPLHSIEKQInEVLGIHKGLigkvaTKRTLE-----LLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELL 179
Cdd:PRK13536  124 NLDLEFTVRENL-LVFGRYFGM-----STREIEavipsLLEFARL---ESKADARVSDLSGGMKRRLTLARALINDPQLL 194

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 180 IADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGC-IVE 238
Cdd:PRK13536  195 ILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRkIAE 253
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 7-239 1.84e-15

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 74.27  E-value: 1.84e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLARHpSGTIEYSGQNLLNLkEKT 86
Cdd:cd03247     1 LSINN--VSFSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKS----TLLQLLTGDLKPQ-QGEITLDGVPVSDL-EKA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIrgnrIAMIFQEPmtslnplHSIEKQINEVLGIhkgligkvatkrtlellemvgipepekrlkalphELSGGQRQRV 166
Cdd:cd03247    73 LSSL----ISVLNQRP-------YLFDTTLRNNLGR----------------------------------RFSGGERQRL 107

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 167 MIAMALANEPELLIADEPTTALDVTVQlkILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQ 239
Cdd:cd03247   108 ALARILLQDAPIVLLDEPTVGLDPITE--RQLLSLIFEVLKDKTLIWITHHLTGIEH-MDKILFLENGKIIMQ 177
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
 31-236 1.98e-15

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 75.66  E-value: 1.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  31 FDIKRGETLALVGESGSGKSVTAHSILRLLPyplarHPSGTIEYSGQNllnlKEKTIRHIR--GNRIAMIFQEPMtslnp 108
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIP-----PAKGTVKVAGAS----PGKGWRHIGyvPQRHEFAWDFPI----- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 lhSIEkqiNEVLGIHKGLIG-----KVATKR-TLELLEMVGIPEPEKRLKAlphELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:TIGR03771  67 --SVA---HTVMSGRTGHIGwlrrpCVADFAaVRDALRRVGLTELADRPVG---ELSGGQRQRVLVARALATRPSVLLLD 138

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 183 EPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVCVMQRGCI 236
Cdd:TIGR03771 139 EPFTGLDMPTQELLTELFIEL-AGAGTAILMTTHDLAQAMATCDRVVLLNGRVI 191
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 274-509 1.99e-15

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 76.22  E-value: 1.99e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 274 PMLTVEDLKVwfpikkgllkkTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAI-----LRLIgsKGGIRFEGKQ 348
Cdd:CHL00131    6 PILEIKNLHA-----------SVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIaghpaYKIL--EGDILFKGES 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDSLTQQQvrplRREMQV--VFQDPFgslsprmcvsQIVG----EGLRI-----HKMGTEAEQE-----QAIIAALKEVG 412
Cdd:CHL00131   73 ILDLEPEE----RAHLGIflAFQYPI----------EIPGvsnaDFLRLaynskRKFQGLPELDpleflEIINEKLKLVG 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 413 LDPETRHRYPHE-FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISH-----DLa 486
Cdd:CHL00131  139 MDPSFLSRNVNEgFSGGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSEN-SIILITHyqrllDY- 216

                         250       260
                  ....*....|....*....|...
gi 1834229548 487 VVKALSHqlmVVKQGQVVEQGDA 509
Cdd:CHL00131  217 IKPDYVH---VMQNGKIIKTGDA 236
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 19-236 2.31e-15

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 75.87  E-value: 2.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  19 GERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYplARHPSGTIEYSGQNLLNLKEKTIRhirgnriaMI 98
Cdd:PRK11247   23 GER--TVLNQLDLHIPAGQFVAVVGRSGCGKS----TLLRLLAG--LETPSAGELLAGTAPLAEAREDTR--------LM 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  99 FQEpmTSLNPLHSIekqINEVlGIhkGLIGKVATkRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPEL 178
Cdd:PRK11247   87 FQD--ARLLPWKKV---IDNV-GL--GLKGQWRD-AALQALAAVGL---ADRANEWPAALSGGQKQRVALARALIHRPGL 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 179 LIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCI 236
Cdd:PRK11247  155 LLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 24-238 2.53e-15

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 75.26  E-value: 2.53e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLlpypLAR--HP-SGTIEysgqnllnlkektirhIRGnRIAMIFq 100
Cdd:cd03220    36 WALKDVSFEVPRGERIGLIGRNGAGKS----TLLRL----LAGiyPPdSGTVT----------------VRG-RVSSLL- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 101 EPMTSLNPLHSIEKQINEVLGIHkGLIGKVATKRTLELLEMVGIPEP-EKRLKalphELSGGQRQRVMIAMALANEPELL 179
Cdd:cd03220    90 GLGGGFNPELTGRENIYLNGRLL-GLSRKEIDEKIDEIIEFSELGDFiDLPVK----TYSSGMKARLAFAIATALEPDIL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 180 IADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVE 238
Cdd:cd03220   165 LIDEVLAVGDAAFQEKCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIRF 222
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 312-507 2.80e-15

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 78.55  E-value: 2.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 312 GQTLGIVGESGSGKSTL--GLAILRLIGSKGG--IRFEGKQLDsltqqqvrplRREMQV----VFQDP--FGSLSPRMCV 381
Cdd:TIGR00955  51 GELLAVMGSSGAGKTTLmnALAFRSPKGVKGSgsVLLNGMPID----------AKEMRAisayVQQDDlfIPTLTVREHL 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 382 sqIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDP--ETRHRYPHE---FSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:TIGR00955 121 --MFQAHLRMPRRVTKKEKRERVDEVLQALGLRKcaNTRIGVPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLD 198

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 457 RTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:TIGR00955 199 SFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLG 249
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 5-221 5.83e-15

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 74.77  E-value: 5.83e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarhPSgtieysgqnllnlkE 84
Cdd:PRK09544    3 SLVSLENVSVSF--GQR--RVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVA------PD--------------E 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KTIRHIRGNRIAMIFQE-PMTSLNPLhSIEKQINEVLGIHKGLIGKvATKRTlellemvgipEPEKRLKALPHELSGGQR 163
Cdd:PRK09544   59 GVIKRNGKLRIGYVPQKlYLDTTLPL-TVNRFLRLRPGTKKEDILP-ALKRV----------QAGHLIDAPMQKLSGGET 126

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLV 221
Cdd:PRK09544  127 QRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLV 184
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
23-218 6.10e-15

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 74.74  E-value: 6.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNlkektirhiRGNRIAMIFQEp 102
Cdd:PRK11248   14 KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQ-----HGSITLDGKPVEG---------PGAERGVVFQN- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 mTSLNPLHSIekQINEVLGIHKGLIGKVATK-RTLELLEMVGIPEPEKRLkalPHELSGGQRQRVMIAMALANEPELLIA 181
Cdd:PRK11248   79 -EGLLPWRNV--QDNVAFGLQLAGVEKMQRLeIAHQMLKKVGLEGAEKRY---IWQLSGGQRQRVGIARALAANPQLLLL 152

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1834229548 182 DEPTTALDVTVQLKILELLKELQARLGMALLLISHDL 218
Cdd:PRK11248  153 DEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDI 189
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 263-521 6.63e-15

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 74.56  E-value: 6.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 263 SGTPATNVVG-PPMLTVEDLKVWFpikKGLLKKTVDYVKAVdginfsLPQGQTLGIVGESGSGKSTLGLAILRLIGS-KG 340
Cdd:cd03288     6 SGSSNSGLVGlGGEIKIHDLCVRY---ENNLKPVLKHVKAY------IKPGQKVGICGRTGSGKSSLSLAFFRMVDIfDG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 341 GIRFEGKQLDSLTQQQvrpLRREMQVVFQDPF---GS----LSP-RMCVSQIVGEGLRIhkmgteaEQEQAIIAALKEvG 412
Cdd:cd03288    77 KIVIDGIDISKLPLHT---LRSRLSIILQDPIlfsGSirfnLDPeCKCTDDRLWEALEI-------AQLKNMVKSLPG-G 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 413 LDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLrsLQSKYNLTYLFISHDLAVVKAlS 492
Cdd:cd03288   146 LDAVVTEG-GENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVV--MTAFADRTVVTIAHRVSTILD-A 221

                         250       260
                  ....*....|....*....|....*....
gi 1834229548 493 HQLMVVKQGQVVEQGDAQSIFAAPQHPYT 521
Cdd:cd03288   222 DLVLVLSRGILVECDTPENLLAQEDGVFA 250
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
7-245 9.89e-15

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 76.98  E-value: 9.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLlpYPLArhpSGTIEYSGqnlLNLKEKT 86
Cdd:PRK11176  342 IEFRN--VTFTYPGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRF--YDID---EGEILLDG---HDLRDYT 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRgNRIAMIFQEpmtslnpLHSIEKQI-NEVLGIHKGLIGKVATKRTLELL-EMVGIPEPEKRLKALPHE----LSG 160
Cdd:PRK11176  412 LASLR-NQVALVSQN-------VHLFNDTIaNNIAYARTEQYSREQIEEAARMAyAMDFINKMDNGLDTVIGEngvlLSG 483

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 161 GQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQArlGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQA 240
Cdd:PRK11176  484 GQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQK--NRTSLVIAHRLSTIEK-ADEILVVEDGEIVERG 560


                  ....*
gi 1834229548 241 SCEQL 245
Cdd:PRK11176  561 THAEL 565
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 6-245 1.11e-14

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 76.79  E-value: 1.11e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplARH---PSGTIEYSGQNLLNL 82
Cdd:PRK11160  338 SLTLNN--VSFTYPDQPQPVLKGLSLQIKAGEKVALLGRTGCGKS----TLLQLL----TRAwdpQQGEILLNGQPIADY 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 KEKTIRhirgNRIAMIFQEP---MTSL--NPLHSIEKQINEVLgihkgligkvatkrtLELLEMVGIP---EPEKRLKAL 154
Cdd:PRK11160  408 SEAALR----QAISVVSQRVhlfSATLrdNLLLAAPNASDEAL---------------IEVLQQVGLEkllEDDKGLNAW 468

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 PHE----LSGGQRQRVMIAMALANEPELLIADEPTTALD-VTVQLKILELLKELQarlGMALLLISHDLNLVKRIaHRVC 229
Cdd:PRK11160  469 LGEggrqLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDaETERQILELLAEHAQ---NKTVLMITHRLTGLEQF-DRIC 544

                         250
                  ....*....|....*.
gi 1834229548 230 VMQRGCIVEQASCEQL 245
Cdd:PRK11160  545 VMDNGQIIEQGTHQEL 560
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 7-249 1.39e-14

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 73.58  E-value: 1.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKT 86
Cdd:COG4604     2 IEIKNVSKRY--GG--KVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPD-----SGEVLVDGLDVATTPSRE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHirgnRIAMIFQEPmtSLNPLHSIEkqinEVLGI-----HKGLIGK---VATKRTLELLEmvgipepekrLKALPH-- 156
Cdd:COG4604    73 LAK----RLAILRQEN--HINSRLTVR----ELVAFgrfpySKGRLTAedrEIIDEAIAYLD----------LEDLADry 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 --ELSGGQRQRVMIAMALANEPELLIADEPTTALDVtvqlkilellkeLQARLGMALL------------LISHDLNLVK 222
Cdd:COG4604   133 ldELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDM------------KHSVQMMKLLrrladelgktvvIVLHDINFAS 200

                         250       260
                  ....*....|....*....|....*..
gi 1834229548 223 RIAHRVCVMQRGCIVEQASCEQLFRAP 249
Cdd:COG4604   201 CYADHIVAMKDGRVVAQGTPEEIITPE 227
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 29-250 1.47e-14

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 73.43  E-value: 1.47e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSVTAHSILRLLPYplarhpSGTIEYSGQNLLNLKEKTIRHIRG-----NR--IAM-IFQ 100
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPG------SGSIQFAGQPLEAWSAAELARHRAylsqqQTppFAMpVFQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 101 EPMTSL---NPLHSIEKQINEVLgihkgligkvatkrtlellEMVGIpepEKRLKALPHELSGGQRQRVMIAMAL----- 172
Cdd:PRK03695   89 YLTLHQpdkTRTEAVASALNEVA-------------------EALGL---DDKLGRSVNQLSGGEWQRVRLAAVVlqvwp 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 173 ANEPE--LLIADEPTTALDVTvQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQ 250
Cdd:PRK03695  147 DINPAgqLLLLDEPMNSLDVA-QQAALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPEN 225
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 31-488 1.75e-14

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 76.14  E-value: 1.75e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  31 FDIKRGETLALVGESGSGKS----VTAHSIL---------------RLLPYPlARHPSGTI-EYSGQNLLNLKEKTIRHI 90
Cdd:PRK11147   24 LHIEDNERVCLVGRNGAGKStlmkILNGEVLlddgriiyeqdlivaRLQQDP-PRNVEGTVyDFVAEGIEEQAEYLKRYH 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  91 RGNRIAMifQEPMTS-LNPLhsieKQINEVLGIHKGLIGKVATKRTLELLEMvgipEPEKRLKalphELSGGQRQRVMIA 169
Cdd:PRK11147  103 DISHLVE--TDPSEKnLNEL----AKLQEQLDHHNLWQLENRINEVLAQLGL----DPDAALS----SLSGGWLRKAALG 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 170 MALANEPELLIADEPTTALDVTVQLKILELLKELQArlgmALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF--- 246
Cdd:PRK11147  169 RALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQG----SIIFISHDRSFIRNMATRIVDLDRGKLVSYPGNYDQYlle 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 247 -------RAPQHPYTRELLAAEPS----GTPA----------------------TNVVGPPMLTVEDL----KVWFPIKK 289
Cdd:PRK11147  245 keealrvEELQNAEFDRKLAQEEVwirqGIKArrtrnegrvralkalrrerserREVMGTAKMQVEEAsrsgKIVFEMEN 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 290 glLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTL-GLAILRLIGSKGGIRFeGKQLDSLTQQQVRplrremqvvf 368
Cdd:PRK11147  325 --VNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLlKLMLGQLQADSGRIHC-GTKLEVAYFDQHR---------- 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 qdpfGSLSPRMCVSQIVGEGlrihKMGTEAE-QEQAIIAALKEVgLDPETRHRYP-HEFSGGQRQRIAIARaLVLKPA-L 445
Cdd:PRK11147  392 ----AELDPEKTVMDNLAEG----KQEVMVNgRPRHVLGYLQDF-LFHPKRAMTPvKALSGGERNRLLLAR-LFLKPSnL 461

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 1834229548 446 ILLDEPTSALDrtvqRQVVELLRSLQSKYNLTYLFISHDLAVV 488
Cdd:PRK11147  462 LILDEPTNDLD----VETLELLEELLDSYQGTVLLVSHDRQFV 500
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 7-221 2.27e-14

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 72.01  E-value: 2.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEfvVGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLlnlkeKT 86
Cdd:TIGR01189   1 LAARNLACS--RGER--MLFEGLSFTLNAGEALQVTGPNGIGKT----TLLRILA-GLLRPDSGEVRWNGTPL-----AE 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRGNRIAMIFQEPmtSLNPLHSIEKQINEVLGIHKGligkvATKRTLELLEMVGIPEPEKRLKalpHELSGGQRQRV 166
Cdd:TIGR01189  67 QRDEPHENILYLGHLP--GLKPELSALENLHFWAAIHGG-----AQRTIEDALAAVGLTGFEDLPA---AQLSAGQQRRL 136

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 167 MIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLV 221
Cdd:TIGR01189 137 ALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAHLARGGIVLLTTHQDLGLV 191
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 8-222 2.29e-14

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 72.30  E-value: 2.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRDLAVEFVVGERC--QRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplarhpsgtieysgqnllnlkek 85
Cdd:COG2401    26 RVAIVLEAFGVELRVveRYVLRDLNLEIEPGEIVLIVGASGSGKS----TLLRLL------------------------- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 tIRHIRGNRIAMIFQEPMTSLNPLHSIEKQInevlgihkGLIGKVATKrtLELLEMVGIPEPEKrLKALPHELSGGQRQR 165
Cdd:COG2401    77 -AGALKGTPVAGCVDVPDNQFGREASLIDAI--------GRKGDFKDA--VELLNAVGLSDAVL-WLRRFKELSTGQKFR 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVK 222
Cdd:COG2401   145 FRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVID 201
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
25-239 3.47e-14

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 74.11  E-value: 3.47e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEKTirhiRGnrIAMIFQE--- 101
Cdd:PRK11650   19 VIKGIDLDVADGEFIVLVGPSGCGKS----TLLRMVA-GLERITSGEIWIGGRVVNELEPAD----RD--IAMVFQNyal 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 -P-MTSLN-----------PLHSIEKQINEVlgihkgligkvatKRTLELLEMvgipepekrLKALPHELSGGQRQRVMI 168
Cdd:PRK11650   88 yPhMSVREnmayglkirgmPKAEIEERVAEA-------------ARILELEPL---------LDRKPRELSGGQRQRVAM 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 169 AMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGcIVEQ 239
Cdd:PRK11650  146 GRAIVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGG-VAEQ 215
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 26-256 3.66e-14

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 72.51  E-value: 3.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSvtahSILR-------LLPYPLArhpSGTIEYSGQNLlNLKEKTIRHIRgNRIAMI 98
Cdd:PRK14243   26 VKNVWLDIPKNQITAFIGPSGCGKS----TILRcfnrlndLIPGFRV---EGKVTFHGKNL-YAPDVDPVEVR-RRIGMV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  99 FQEPmtslNPL-HSIEKQIN---EVLGiHKGLIGKVATKrtlELLEMVGIPEPEKRLKALPHELSGGQRQRVMIAMALAN 174
Cdd:PRK14243   97 FQKP----NPFpKSIYDNIAygaRING-YKGDMDELVER---SLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIAV 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 175 EPELLIADEPTTALD--VTVQLKILELLKELQarlgMALLLISHDLNLVKRIAHRVCVM---------QRGCIVEQASCE 243
Cdd:PRK14243  169 QPEVILMDEPCSALDpiSTLRIEELMHELKEQ----YTIIIVTHNMQQAARVSDMTAFFnveltegggRYGYLVEFDRTE 244

                         250
                  ....*....|...
gi 1834229548 244 QLFRAPQHPYTRE 256
Cdd:PRK14243  245 KIFNSPQQQATRD 257
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 289-509 5.74e-14

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 75.33  E-value: 5.74e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  289 KGLLKKTVDYVKAV-DGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQvrpLRREMQVV 367
Cdd:TIGR01271 1221 QGLTAKYTEAGRAVlQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTEGEIQIDGVSWNSVTLQT---WRKAFGVI 1297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  368 FQDPFgslsprmcvsqIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHE-----------FSGGQRQRIAIA 436
Cdd:TIGR01271 1298 PQKVF-----------IFSGTFRKNLDPYEQWSDEEIWKVAEEVGLK-SVIEQFPDKldfvlvdggyvLSNGHKQLMCLA 1365

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548  437 RALVLKPALILLDEPTSALDrTVQRQVVEllRSL-QSKYNLTYLFISHDLAVVkaLSHQLMVVKQGQVVEQGDA 509
Cdd:TIGR01271 1366 RSILSKAKILLLDEPSAHLD-PVTLQIIR--KTLkQSFSNCTVILSEHRVEAL--LECQQFLVIEGSSVKQYDS 1434
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 292-502 6.30e-14

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 69.01  E-value: 6.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIgskggirfegkqldsltqqqvrplrremqvvfqdp 371
Cdd:cd03221     6 LSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTL----LKLI----------------------------------- 46

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 fgslsprmcvsqivgeglrihkMGTEAEQEQAIIaalkevgLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:cd03221    47 ----------------------AGELEPDEGIVT-------WGSTVKIGYFEQLSGGEKMRLALAKLLLENPNLLLLDEP 97

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 452 TSALDRTVQRQVVELLRslqsKYNLTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:cd03221    98 TNHLDLESIEALEEALK----EYPGTVILVSHDRYFLDQVATKIIELEDGK 144
type_I_sec_HlyB TIGR01846
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...
 25-247 8.80e-14

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273831 [Multi-domain]  Cd Length: 694  Bit Score: 74.01  E-value: 8.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLlpYPLARhpsGTIEYSGQNLLNLKEKTIRHirgnRIAMIFQEP-- 102
Cdd:TIGR01846 472 VLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRL--YTPQH---GQVLVDGVDLAIADPAWLRR----QMGVVLQENvl 542

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 --------MTSLNPLHSIEKQIN--EVLGIHKGLIGKVATKRTlELLEMVGipepekrlkalphELSGGQRQRVMIAMAL 172
Cdd:TIGR01846 543 fsrsirdnIALCNPGAPFEHVIHaaKLAGAHDFISELPQGYNT-EVGEKGA-------------NLSGGQRQRIAIARAL 608

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 173 ANEPELLIADEPTTALDVTVQLKILELLKELQArlGMALLLISHDLNLVkRIAHRVCVMQRGCIVEQASCEQLFR 247
Cdd:TIGR01846 609 VGNPRILIFDEATSALDYESEALIMRNMREICR--GRTVIIIAHRLSTV-RACDRIIVLEKGQIAESGRHEELLA 680
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
33-497 8.89e-14

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 74.07  E-value: 8.89e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  33 IKRGETLALVGESGSGKSvTAHSILrllpyplarhpsgtieySGQNLLNL--------KEKTIRHIRGNRIAMIFQEpmt 104
Cdd:PRK13409   96 PKEGKVTGILGPNGIGKT-TAVKIL-----------------SGELIPNLgdyeeepsWDEVLKRFRGTELQNYFKK--- 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 slnpLHSiekqiNEVLGIHK----GLIGKVATKRTLELLEMV---GI-PEPEKRLKALP------HELSGGQRQRVMIAM 170
Cdd:PRK13409  155 ----LYN-----GEIKVVHKpqyvDLIPKVFKGKVRELLKKVderGKlDEVVERLGLENildrdiSELSGGELQRVAIAA 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 171 ALANEPELLIADEPTTALDVtVQlkilellkelqaRLGMA-----------LLLISHDLNLVKRIAHRVCVM--QRGC-- 235
Cdd:PRK13409  226 ALLRDADFYFFDEPTSYLDI-RQ------------RLNVArlirelaegkyVLVVEHDLAVLDYLADNVHIAygEPGAyg 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 236 IVeqasceqlfrapQHPY-TRE--------LLAAE-----------PSGTPATNVVGPPMLTVEDlkvwfpikkglLKKT 295
Cdd:PRK13409  293 VV------------SKPKgVRVgineylkgYLPEEnmrirpepiefEERPPRDESERETLVEYPD-----------LTKK 349

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 296 VDyvkavdgiNFSLP-------QGQTLGIVGESGSGKSTLglaiLRLIGskGGIR-FEGKQLDSLT----QQQVRPlRRE 363
Cdd:PRK13409  350 LG--------DFSLEveggeiyEGEVIGIVGPNGIGKTTF----AKLLA--GVLKpDEGEVDPELKisykPQYIKP-DYD 414

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 364 MQVvfQDPFGSLSPRMCVSQI---VGEGLRIHKMgteaeqeqaiiaalkevgLDpetrhRYPHEFSGGQRQRIAIARALV 440
Cdd:PRK13409  415 GTV--EDLLRSITDDLGSSYYkseIIKPLQLERL------------------LD-----KNVKDLSGGELQRVAIAACLS 469

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 441 LKPALILLDEPTSALDrtV-QR-QVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMV 497
Cdd:PRK13409  470 RDADLYLLDEPSAHLD--VeQRlAVAKAIRRIAEEREATALVVDHDIYMIDYISDRLMV 526
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 28-248 9.85e-14

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 73.70  E-value: 9.85e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKTIRHIrgnrIAMIFQEpmTSL- 106
Cdd:COG5265   376 GVSFEVPAGKTVAIVGPSGAGKS----TLARLL-FRFYDVTSGRILIDGQDIRDVTQASLRAA----IGIVPQD--TVLf 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 107 -----------NPLHSiEKQINEVLG---IH---KGLIGKVATkrtlelleMVGipepEKRLKalpheLSGGQRQRVMIA 169
Cdd:COG5265   445 ndtiayniaygRPDAS-EEEVEAAARaaqIHdfiESLPDGYDT--------RVG----ERGLK-----LSGGEKQRVAIA 506

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 170 MALANEPELLIADEPTTALD-VTVQLKILELLKELQARlgmALLLISHDLNLVKRiAHRVCVMQRGCIVEQASCEQLFRA 248
Cdd:COG5265   507 RTLLKNPPILIFDEATSALDsRTERAIQAALREVARGR---TTLVIAHRLSTIVD-ADEILVLEAGRIVERGTHAELLAQ 582
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 304-495 1.10e-13

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 69.83  E-value: 1.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLDsltqQQVRPLRREMQVVFQDPF--GSLS 376
Cdd:cd03231    18 GLSFTLAAGEALQVTGPNGSGKTTL----LRILAglsppLAGRVLLNGGPLD----FQRDSIARGLLYLGHAPGikTTLS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 PRmcvsqivgEGLRI-HKMGTEAEQEQAiiaaLKEVGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:cd03231    90 VL--------ENLRFwHADHSDEQVEEA----LARVGLNG-FEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTAL 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQL 495
Cdd:cd03231   157 DKAGVARFAEAMAGHCARGGMVVLTTHQDLGLSEAGAREL 196
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 7-249 1.16e-13

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 70.65  E-value: 1.16e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLKekt 86
Cdd:cd03218     1 LRAENLSKRY--GKRK--VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLV-----KPDSGKILLDGQDITKLP--- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 iRHIRGnRIAMIF--QEPmtSLNPLHSIEKQINEVLGIHKgLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQ 164
Cdd:cd03218    69 -MHKRA-RLGIGYlpQEA--SIFRKLTVEENILAVLEIRG-LSKKEREEKLEELLEEFHI---THLRKSKASSLSGGERR 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALD-VTVQLKILELLKELQarLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCE 243
Cdd:cd03218   141 RVEIARALATNPKFLLLDEPFAGVDpIAVQDIQKIIKILKD--RGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPE 218


                  ....*.
gi 1834229548 244 QLFRAP 249
Cdd:cd03218   219 EIAANE 224
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 26-234 1.37e-13

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 70.19  E-value: 1.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNlkektirhiRGNRIAMIFQEpmTS 105
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKS----TLLNLIS-GLAQPTSGGVILEGKQITE---------PGPDRMVVFQN--YS 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LNPLHSIEKQIneVLGIHKGLIGKVATKRTL---ELLEMVGIPEP-EKRlkalPHELSGGQRQRVMIAMALANEPELLIA 181
Cdd:TIGR01184  65 LLPWLTVRENI--ALAVDRVLPDLSKSERRAiveEHIALVGLTEAaDKR----PGQLSGGMKQRVAIARALSIRPKVLLL 138

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 182 DEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:TIGR01184 139 DEPFGALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 158-484 1.69e-13

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 73.05  E-value: 1.69e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALDV-TVQLKILELlkelqARLGMALLLISHDLNLVKRIAHRVCVMQRG-C 235
Cdd:TIGR03719 162 LSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAeSVAWLERHL-----QEYPGTVVAVTHDRYFLDNVAGWILELDRGrG 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 236 I----------------VEQASCEQLFRAP----------QHPYTR------------ELLAAEPSGTPATN-VVGPPML 276
Cdd:TIGR03719 237 IpwegnysswleqkqkrLEQEEKEESARQKtlkrelewvrQSPKGRqakskarlaryeELLSQEFQKRNETAeIYIPPGP 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 277 TVEDLKVWFpikKGLLKKTVDYVkAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGSK-----GGIRF-EGKQLD 350
Cdd:TIGR03719 317 RLGDKVIEA---ENLTKAFGDKL-LIDDLSFKLPPGGIVGVIGPNGAGKSTL----FRMITGQeqpdsGTIEIgETVKLA 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 351 SLTQQqvrplrREmqvvfqdpfgSLSPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRhryPHEFSGGQR 430
Cdd:TIGR03719 389 YVDQS------RD----------ALDPNKTVWEEISGGLDIIKLGKREIPSRAYVGRFNFKGSDQQKK---VGQLSGGER 449

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 431 QRIAIARALVLKPALILLDEPTSALDrtvqrqvVELLRSLQS---KYNLTYLFISHD 484
Cdd:TIGR03719 450 NRVHLAKTLKSGGNVLLLDEPTNDLD-------VETLRALEEallNFAGCAVVISHD 499
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 30-483 2.06e-13

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 72.35  E-value: 2.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  30 SFDIKRGETLALVGESGSGKSVtahsilrllpypLARHPSGT-IEYSGQnllnlkektiRHIRGNRIAMIFQEpmtSLNP 108
Cdd:PRK10938   23 SLTLNAGDSWAFVGANGSGKSA------------LARALAGElPLLSGE----------RQSQFSHITRLSFE---QLQK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 LHSIEKQIN--EVLGIHKGLIGKVA----------TKRTLELLEMVGI-PEPEKRLKalphELSGGQRQRVMIAMALANE 175
Cdd:PRK10938   78 LVSDEWQRNntDMLSPGEDDTGRTTaeiiqdevkdPARCEQLAQQFGItALLDRRFK----YLSTGETRKTLLCQALMSE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 176 PELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVM---------QRGCIVEQASCEQLF 246
Cdd:PRK10938  154 PDLLILDEPFDGLDVASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLadctlaetgEREEILQQALVAQLA 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 247 RAPQHPYTRELLAAEPSGTPATNVVGPPMLtvedlkvwfpikkgLLKKTVDY--VKAVDGINFSLPQGQTLGIVGESGSG 324
Cdd:PRK10938  233 HSEQLEGVQLPEPDEPSARHALPANEPRIV--------------LNNGVVSYndRPILHNLSWQVNPGEHWQIVGPNGAG 298

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 325 KSTLgLAI------------LRLIGSKGG-----------IRFEGKQL--DSLTQQQVRplrremQVVFQDPFGSLSprm 379
Cdd:PRK10938  299 KSTL-LSLitgdhpqgysndLTLFGRRRGsgetiwdikkhIGYVSSSLhlDYRVSTSVR------NVILSGFFDSIG--- 368

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 cVSQIVGEGLRIhkmgtEAEQEQAIIaalkevGLDPETRHRYPHEFSGGQrQRIA-IARALVLKPALILLDEPTSALD-- 456
Cdd:PRK10938  369 -IYQAVSDRQQK-----LAQQWLDIL------GIDKRTADAPFHSLSWGQ-QRLAlIVRALVKHPTLLILDEPLQGLDpl 435

                         490       500
                  ....*....|....*....|....*...
gi 1834229548 457 -RTVQRQVVELLRSlQSKYNLtyLFISH 483
Cdd:PRK10938  436 nRQLVRRFVDVLIS-EGETQL--LFVSH 460
PLN03211 PLN03211
ABC transporter G-25; Provisional
 302-513 2.71e-13

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 72.60  E-value: 2.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGgirFEGKQLDSlTQQQVRPLRREMQVVFQDPFgsLSPRMCV 381
Cdd:PLN03211   84 LNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNN---FTGTILAN-NRKPTKQILKRTGFVTQDDI--LYPHLTV 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 382 SQ--IVGEGLRIHKMGTEAEQEQAIIAALKEVGLDPETRHRYPHEF----SGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:PLN03211  158 REtlVFCSLLRLPKSLTKQEKILVAESVISELGLTKCENTIIGNSFirgiSGGERKRVSIAHEMLINPSLLILDEPTSGL 237

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG---DAQSIF 513
Cdd:PLN03211  238 DATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGkgsDAMAYF 298
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 12-228 3.64e-13

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 68.29  E-value: 3.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  12 LAVEFVVGERCQRVV-EGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKEKTIR-- 88
Cdd:cd03231     1 LEADELTCERDGRALfSGLSFTLAAGEALQVTGPNGSGKT----TLLRILA-GLSPPLAGRVLLNGGPLDFQRDSIARgl 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  89 ----HIRGNRIAMIFQEPMTSLNPLHSiekqinevlgihkgligkvaTKRTLELLEMVGIPEPEKRLKalpHELSGGQRQ 164
Cdd:cd03231    76 lylgHAPGIKTTLSVLENLRFWHADHS--------------------DEQVEEALARVGLNGFEDRPV---AQLSAGQQR 132

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 165 RVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRV 228
Cdd:cd03231   133 RVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGHCARGGMVVLTTHQDLGLSEAGAREL 196
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 23-250 3.66e-13

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 69.15  E-value: 3.66e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARHpsgTIEYSGQNLLNLKEktiRHIRGnrIAMIFQEP 102
Cdd:PRK10895   16 RRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNI---IIDDEDISLLPLHA---RARRG--IGYLPQEA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 mtSLNPLHSIEKQINEVLGIHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:PRK10895   88 --SIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHI---EHLRDSMGQSLSGGERRRVEIARALAANPKFILLD 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 183 EPTTALDvTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQ 250
Cdd:PRK10895  163 EPFAGVD-PISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEH 229
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 7-189 5.08e-13

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 67.96  E-value: 5.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFV--VGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLARHP-SGTIEYSGQNLlnlK 83
Cdd:cd03213     4 LSFRNLTVTVKssPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKS----TLLNALAGRRTGLGvSGEVLINGRPL---D 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRhirgNRIAMIFQEPMtslnpLHSiEKQINEVLGIHKGLIGkvatkrtlellemvgipepekrlkalpheLSGGQR 163
Cdd:cd03213    77 KRSFR----KIIGYVPQDDI-----LHP-TLTVRETLMFAAKLRG-----------------------------LSGGER 117

                         170       180
                  ....*....|....*....|....*.
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALD 189
Cdd:cd03213   118 KRVSIALELVSNPSLLFLDEPTSGLD 143
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 28-250 5.77e-13

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 68.71  E-value: 5.77e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYplarhpSGTIEYSGQNLLNLKEKTIRHIRgnriAMIFQEPMTSLN 107
Cdd:COG4138    14 PISAQVNAGELIHLIGPNGAGKSTLLARMAGLLPG------QGEILLNGRPLSDWSAAELARHR----AYLSQQQSPPFA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 108 -PL-HSIEkqinevLGIHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMAL------AN-EPEL 178
Cdd:COG4138    84 mPVfQYLA------LHQPAGASSEAVEQLLAQLAEALGL---EDKLSRPLTQLSGGEWQRVRLAAVLlqvwptINpEGQL 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 179 LIADEPTTALDVTvQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQ 250
Cdd:COG4138   155 LLLDEPMNSLDVA-QQAALDRLLRELCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPEN 225
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 295-503 6.58e-13

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 69.11  E-value: 6.58e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 295 TVDYVKA----VDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQvrpLRREMQVVFQD 370
Cdd:cd03289     9 TAKYTEGgnavLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGDIQIDGVSWNSVPLQK---WRKAFGVIPQK 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 371 PFgslsprmcvsqIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHE-----------FSGGQRQRIAIARAL 439
Cdd:cd03289    86 VF-----------IFSGTFRKNLDPYGKWSDEEIWKVAEEVGLK-SVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSV 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 440 VLKPALILLDEPTSALDRTVQRQVVELLRslQSKYNLTYLFISHDLAVVKAlSHQLMVVKQGQV 503
Cdd:cd03289   154 LSKAKILLLDEPSAHLDPITYQVIRKTLK--QAFADCTVILSEHRIEAMLE-CQRFLVIEENKV 214
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 305-489 6.70e-13

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 71.60  E-value: 6.70e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG--IRFEGKQLDSLTQQQ-------------------------- 356
Cdd:PTZ00265  1187 LTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKNDhhIVFKNEHTNDMTNEQdyqgdeeqnvgmknvnefsltkeggs 1266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  357 ------------------------VRPLRREMQVVFQDPfgslsprMCVSQIVGEGLrihKMGTEAEQEQAIIAALKEVG 412
Cdd:PTZ00265  1267 gedstvfknsgkilldgvdicdynLKDLRNLFSIVSQEP-------MLFNMSIYENI---KFGKEDATREDVKRACKFAA 1336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  413 LDpETRHRYPHEF-----------SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFI 481
Cdd:PTZ00265  1337 ID-EFIESLPNKYdtnvgpygkslSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITI 1415


                   ....*...
gi 1834229548  482 SHDLAVVK 489
Cdd:PTZ00265  1416 AHRIASIK 1423
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 2-189 6.70e-13

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 70.99  E-value: 6.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILR----LLPYplarhpsgtieYSGq 77
Cdd:COG4178   358 SEDGALALEDLTLRTPDG---RPLLEDLSLSLKPGERLLITGPSGSGKS----TLLRaiagLWPY-----------GSG- 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  78 nllnlkekTIRHIRGNRIAMIFQEPMTslnPLHSIEKQInevlgIHKGLIGKVATKRTLELLEMVGIPEPEKRL---KAL 154
Cdd:COG4178   419 --------RIARPAGARVLFLPQRPYL---PLGTLREAL-----LYPATAEAFSDAELREALEAVGLGHLAERLdeeADW 482

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1834229548 155 PHELSGGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:COG4178   483 DQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALD 517
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 22-189 7.80e-13

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 68.07  E-value: 7.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  22 CQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplarHPSGTIeySGQNLLNLKEKTiRHIRGNRIAMIFQ- 100
Cdd:cd03234    19 YARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRV------EGGGTT--SGQILFNGQPRK-PDQFQKCVAYVRQd 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 101 ----------EPMT----SLNPLHSIEKQINEVlgihkgligkVATKRTLEL-LEMVGipepEKRLKALphelSGGQRQR 165
Cdd:cd03234    90 dillpgltvrETLTytaiLRLPRKSSDAIRKKR----------VEDVLLRDLaLTRIG----GNLVKGI----SGGERRR 151

                         170       180
                  ....*....|....*....|....
gi 1834229548 166 VMIAMALANEPELLIADEPTTALD 189
Cdd:cd03234   152 VSIAVQLLWDPKVLILDEPTSGLD 175
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 305-515 9.60e-13

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 71.13  E-value: 9.60e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIGS-KGGIRFEGKQLDSLTqqqVRPLRREMQVVFQDPF---GSLspRMC 380
Cdd:TIGR00957 1305 INVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESaEGEIIIDGLNIAKIG---LHDLRFKITIIPQDPVlfsGSL--RMN 1379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  381 V---SQIVGEGLRihkMGTEAEQEQAIIAALKEvGLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:TIGR00957 1380 LdpfSQYSDEEVW---WALELAHLKTFVSALPD-KLDHECAEG-GENLSVGQRQLVCLARALLRKTKILVLDEATAAVDL 1454

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548  458 TVQRQVVELLRSLQSkyNLTYLFISHDLAVVKALShQLMVVKQGQVVEQGDAQSIFAA 515
Cdd:TIGR00957 1455 ETDNLIQSTIRTQFE--DCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQ 1509
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 5-220 1.05e-12

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 67.21  E-value: 1.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVefVVGERCqrVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNLLNLKE 84
Cdd:PRK13539    1 MMLEGEDLAC--VRGGRV--LFSGLSFTLAAGEALVLTGPNGSGKT----TLLRLIA-GLLPPAAGTIKLDGGDIDDPDV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KTIRHIRGNRIAMifqepmtslNPLHSIEKQIN---EVLGIHKGLIgkvatkrtLELLEMVGIPepekRLKALP-HELSG 160
Cdd:PRK13539   72 AEACHYLGHRNAM---------KPALTVAENLEfwaAFLGGEELDI--------AAALEAVGLA----PLAHLPfGYLSA 130

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 161 GQRQRVMIA-MALANEPeLLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNL 220
Cdd:PRK13539  131 GQKRRVALArLLVSNRP-IWILDEPTAALDAAAVALFAELIRAHLAQGGIVIAATHIPLGL 190
PLN03232 PLN03232
ABC transporter C family member; Provisional
 304-536 1.45e-12

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 70.78  E-value: 1.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  304 GINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKqldSLTQQQVRPLRREMQVVFQDPfgslsprMCVS 382
Cdd:PLN03232  1254 GLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVElEKGRIMIDDC---DVAKFGLTDLRRVLSIIPQSP-------VLFS 1323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  383 QIVGEGLRIHKMGTEAEQEQAI-IAALKEV------GLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:PLN03232  1324 GTVRFNIDPFSEHNDADLWEALeRAHIKDVidrnpfGLDAEVSEG-GENFSVGQRQLLSLARALLRRSKILVLDEATASV 1402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  456 D-RT---VQRQVVELLRSlqskynLTYLFISHDLAVVKALShQLMVVKQGQVVEQGDAQSIFAAPQHPYTQQLLEAAflv 531
Cdd:PLN03232  1403 DvRTdslIQRTIREEFKS------CTMLVIAHRLNTIIDCD-KILVLSSGQVLEYDSPQELLSRDTSAFFRMVHSTG--- 1472


                   ....*
gi 1834229548  532 PATAQ 536
Cdd:PLN03232  1473 PANAQ 1477
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
36-249 1.60e-12

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 67.89  E-value: 1.60e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  36 GETLALVGESGSGKSvtahSILRLLpyplARH---PSGTIEYSGQNLLNLKEKTIrhirGNRIAMIFQ-----EPMTsln 107
Cdd:PRK10575   37 GKVTGLIGHNGSGKS----TLLKML----GRHqppSEGEILLDAQPLESWSSKAF----ARKVAYLPQqlpaaEGMT--- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 108 plhsiekqINEVLGIHK-------GLIGKVATKRTLELLEMVGipepekrLKALPHEL----SGGQRQRVMIAMALANEP 176
Cdd:PRK10575  102 --------VRELVAIGRypwhgalGRFGAADREKVEEAISLVG-------LKPLAHRLvdslSGGERQRAWIAMLVAQDS 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 177 ELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAP 249
Cdd:PRK10575  167 RCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGE 239
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 7-248 1.66e-12

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 69.89  E-value: 1.66e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDlaVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLLNLKEKT 86
Cdd:TIGR03375 464 IEFRN--VSFAYPGQETPALDNVSLTIRPGEKVAIIGRIGSGKS----TLLKLL-LGLYQPTEGSVLLDGVDIRQIDPAD 536

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHirgnRIAMIFQEPMTSLNPLHSiekqiNEVLGihKGLIGKVatkRTLELLEMVGIPEPEKRLKA---LP-HE----L 158
Cdd:TIGR03375 537 LRR----NIGYVPQDPRLFYGTLRD-----NIALG--APYADDE---EILRAAELAGVTEFVRRHPDgldMQiGErgrsL 602

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDvtVQLKILELLKELQARLGMALLLISHD---LNLVKRIAhrvcVMQRGC 235
Cdd:TIGR03375 603 SGGQRQAVALARALLRDPPILLLDEPTSAMD--NRSEERFKDRLKRWLAGKTLVLVTHRtslLDLVDRII----VMDNGR 676

                         250
                  ....*....|...
gi 1834229548 236 IVEQASCEQLFRA 248
Cdd:TIGR03375 677 IVADGPKDQVLEA 689
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 304-490 2.26e-12

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 65.84  E-value: 2.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLglaiLRLIG-----SKGGIRFEGKQLdsltqQQVRPLRREmQVVFQDPFGSLSPR 378
Cdd:TIGR01189  18 GLSFTLNAGEALQVTGPNGIGKTTL----LRILAgllrpDSGEVRWNGTPL-----AEQRDEPHE-NILYLGHLPGLKPE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 379 MCVSqivgEGLRIHKMGTEAEQeQAIIAALKEVGLDPETrHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRT 458
Cdd:TIGR01189  88 LSAL----ENLHFWAAIHGGAQ-RTIEDALAAVGLTGFE-DLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKA 161

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1834229548 459 VQRQVVELLRSLQSKYNLTYLFISHDLAVVKA 490
Cdd:TIGR01189 162 GVALLAGLLRAHLARGGIVLLTTHQDLGLVEA 193
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 5-248 2.31e-12

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 67.03  E-value: 2.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFVVGERCQR------------------VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplar 66
Cdd:COG1134     3 SMIEVENVSKSYRLYHEPSRslkelllrrrrtrreefwALKDVSFEVERGESVGIIGRNGAGKS----TLLKLI------ 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  67 hpSGTIE-YSGqnllnlkekTIRhIRGnRIAMIFqEPMTSLNPLHSIEKQInevlgIHKGLIGKVATKRTLELLEMV--- 142
Cdd:COG1134    73 --AGILEpTSG---------RVE-VNG-RVSALL-ELGAGFHPELTGRENI-----YLNGRLLGLSRKEIDEKFDEIvef 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 143 -GIPE----PEKRlkalpheLSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQlkilellKELQARL------GMAL 211
Cdd:COG1134   134 aELGDfidqPVKT-------YSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQ-------KKCLARIrelresGRTV 199

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1834229548 212 LLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRA 248
Cdd:COG1134   200 IFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 1-234 2.59e-12

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 66.94  E-value: 2.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDnLIEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLL 80
Cdd:PRK11300    1 MSQP-LLSVSGLMMRF--GGLL--AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFY-----KPTGGTILLRGQHIE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKE---------KTIRHIRgnriamIFQEpMTSL-NPLHSIEKQINEvlGIHKGLIG--------KVATKRTLELLEMV 142
Cdd:PRK11300   71 GLPGhqiarmgvvRTFQHVR------LFRE-MTVIeNLLVAQHQQLKT--GLFSGLLKtpafrraeSEALDRAATWLERV 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 143 GIPEPEKRLKAlphELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVK 222
Cdd:PRK11300  142 GLLEHANRQAG---NLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVM 218

                         250
                  ....*....|..
gi 1834229548 223 RIAHRVCVMQRG 234
Cdd:PRK11300  219 GISDRIYVVNQG 230
cbiO PRK13644
energy-coupling factor transporter ATPase;
26-249 3.06e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 66.93  E-value: 3.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  26 VEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNL-KEKTIRHIRGnriaMIFQEPMT 104
Cdd:PRK13644   18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLL-----RPQKGKVLVSGIDTGDFsKLQGIRKLVG----IVFQNPET 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 SLnplhsIEKQINEVLGI---HKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIA 181
Cdd:PRK13644   89 QF-----VGRTVEEDLAFgpeNLCLPPIEIRKRVDRALAEIGL---EKYRHRSPKTLSGGQGQCVALAGILTMEPECLIF 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 182 DEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVkRIAHRVCVMQRGCIVEQASCEQLFRAP 249
Cdd:PRK13644  161 DEVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVLSDV 226
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 7-234 3.15e-12

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 64.01  E-value: 3.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplarhpSGTIE-YSGqnllnlkek 85
Cdd:cd03221     1 IELENLSKTY--GGKL--LLKDISLTINPGDRIGLVGRNGAGKS----TLLKLI--------AGELEpDEG--------- 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 TIRHIRGNRIAMIFQepmtslnplhsiekqinevlgihkgligkvatkrtlellemvgipepekrlkalpheLSGGQRQR 165
Cdd:cd03221    56 IVTWGSTVKIGYFEQ---------------------------------------------------------LSGGEKMR 78

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 166 VMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQArlgmALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:cd03221    79 LALAKLLLENPNLLLLDEPTNHLDLESIEALEEALKEYPG----TVILVSHDRYFLDQVATKIIELEDG 143
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
289-512 3.70e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 67.84  E-value: 3.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 289 KGLLKKTVDyVKAVDGINFSLPQGQTLGIVGESGSGKSTlGLAILRLIGSKGGIRfeGKQLDSLTQQQvRPLRREM---Q 365
Cdd:NF000106   17 RGLVKHFGE-VKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGRR--PWRF*TWCANR-RALRRTIg*hR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 366 VVFQDPFGSLSPRMCVsQIVGEGLRIHKMGTEAEQEQAiiaaLKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPAL 445
Cdd:NF000106   92 PVR*GRRESFSGRENL-YMIGR*LDLSRKDARARADEL----LERFSLT-EAAGRAAAKYSGGMRRRLDLAASMIGRPAV 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:NF000106  166 LYLDEPTTGLDPRTRNEVWDEVRSM-VRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 4-238 4.39e-12

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 68.55  E-value: 4.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYsGQN 78
Cdd:COG0488   313 KKVLELEGLSKSY--GDK--TLLDDLSLRIDRGDRIGLIGPNGAGKS----TLLKLLagelePD------SGTVKL-GET 377

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 LlnlkektirhirgnRIAMIFQEpMTSLNPLHSIekqINEVLGIHKGliGKVATKRTLelLEMVGIPePEKRLKALpHEL 158
Cdd:COG0488   378 V--------------KIGYFDQH-QEELDPDKTV---LDELRDGAPG--GTEQEVRGY--LGRFLFS-GDDAFKPV-GVL 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDV-TVQLkilellkelqarLGMAL-------LLISHDLNLVKRIAHRVCV 230
Cdd:COG0488   434 SGGEKARLALAKLLLSPPNVLLLDEPTNHLDIeTLEA------------LEEALddfpgtvLLVSHDRYFLDRVATRILE 501


                  ....*...
gi 1834229548 231 MQRGCIVE 238
Cdd:COG0488   502 FEDGGVRE 509
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
299-509 5.16e-12

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 65.67  E-value: 5.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKST-LGLAILRLIGSKGGIRFEGKqlDSLTQQQVRPLRREMQVVfqdPFGSlsp 377
Cdd:PRK11614   18 IQALHEVSLHINQGEIVTLIGANGAGKTTlLGTLCGDPRATSGRIVFDGK--DITDWQTAKIMREAVAIV---PEGR--- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEGLRIHKMGTEAEQEQAIIAALKEvgLDP---ETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:PRK11614   90 RVFSRMTVEENLAMGGFFAERDQFQERIKWVYE--LFPrlhERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLG 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 455 LDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVV--EQGDA 509
Cdd:PRK11614  168 LAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVleDTGDA 223
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
25-258 6.52e-12

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 66.16  E-value: 6.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLLNLKEKTIrhirGNRIAMIFQEPMT 104
Cdd:PRK10253   22 VAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMT-PA----HGHVWLDGEHIQHYASKEV----ARRIGLLAQNATT 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 SLNPlhSIEKQINEVLGIHKGLIgkvaTKRTLELLEMVGIPEPEKRLKALPHE----LSGGQRQRVMIAMALANEPELLI 180
Cdd:PRK10253   93 PGDI--TVQELVARGRYPHQPLF----TRWRKEDEEAVTKAMQATGITHLADQsvdtLSGGQRQRAWIAMVLAQETAIML 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 181 ADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQAsceqlfrAPQHPYTRELL 258
Cdd:PRK10253  167 LDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQG-------APKEIVTAELI 237
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 305-485 9.65e-12

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 64.66  E-value: 9.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAIL-RLIGSKGGIRFEGKQLDSLTQQQVRPLRR-----------------EMQV 366
Cdd:cd03290    20 INIRIPTGQLTMIVGQVGCGKSSLLLAILgEMQTLEGKVHWSNKNESEPSFEATRSRNRysvayaaqkpwllnatvEENI 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPFGSlsprmcvsqivgeglRIHKMGTEAEQEQAIIAALKeVGLDPETRHRYPHeFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03290   100 TFGSPFNK---------------QRYKAVTDACSLQPDIDLLP-FGDQTEIGERGIN-LSGGQRQRICVARALYQNTNIV 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1834229548 447 LLDEPTSAL-----DRTVQRQVVELLRSLQSkynlTYLFISHDL 485
Cdd:cd03290   163 FLDDPFSALdihlsDHLMQEGILKFLQDDKR----TLVLVTHKL 202
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 4-236 1.05e-11

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 67.26  E-value: 1.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGERcQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLlpYPLArhpsgtieYSGQNLLNLK 83
Cdd:PRK13549  257 EVILEVRNLTAWDPVNPH-IKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGA--YPGR--------WEGEIFIDGK 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRH----IRgNRIAMIFQE-PMTSLNPLHSIEKQIN-EVLG--IHKGLIGKVATKRTL--ELLEM-VGIPEPEKRLK 152
Cdd:PRK13549  326 PVKIRNpqqaIA-QGIAMVPEDrKRDGIVPVMGVGKNITlAALDrfTGGSRIDDAAELKTIleSIQRLkVKTASPELAIA 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 153 alphELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:PRK13549  405 ----RLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQL-VQQGVAIIVISSELPEVLGLSDRVLVMH 479


                  ....
gi 1834229548 233 RGCI 236
Cdd:PRK13549  480 EGKL 483
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 305-500 1.10e-11

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 65.14  E-value: 1.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIgskggirfegkQLDSLTQQQVRPLRREM--QVVFQDPFGSLSprmcvs 382
Cdd:PRK09544   23 VSLELKPGKILTLLGPNGAGKSTLVRVVLGLV-----------APDEGVIKRNGKLRIGYvpQKLYLDTTLPLT------ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 383 qiVGEGLRIHKmgteAEQEQAIIAALKEVglDPETRHRYP-HEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQR 461
Cdd:PRK09544   86 --VNRFLRLRP----GTKKEDILPALKRV--QAGHLIDAPmQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQV 157

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1834229548 462 QVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQ 500
Cdd:PRK09544  158 ALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLNH 196
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
6-245 1.45e-11

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 65.03  E-value: 1.45e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEFvvgeRCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLA--RHPSGTIEYSGqNLLNLK 83
Cdd:PRK09984    4 IIRVEKLAKTF----NQHQALHAVDLNIHHGEMVALLGPSGSGKS----TLLRHLSGLITgdKSAGSHIELLG-RTVQRE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 EKTIRHIRGNR--IAMIFQEpMTSLNPLHSIEKQINEVLGIHK------GLIGKVATKRTLELLEMVGIPE-PEKRLKAL 154
Cdd:PRK09984   75 GRLARDIRKSRanTGYIFQQ-FNLVNRLSVLENVLIGALGSTPfwrtcfSWFTREQKQRALQALTRVGMVHfAHQRVSTL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 155 phelSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:PRK09984  154 ----SGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQG 229

                         250
                  ....*....|.
gi 1834229548 235 CIVEQASCEQL 245
Cdd:PRK09984  230 HVFYDGSSQQF 240
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 273-456 1.72e-11

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 64.28  E-value: 1.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWFPikkgllKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDS 351
Cdd:COG1137     1 MMTLEAENLVKSYG------KRTV-----VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGrIFLDGEDITH 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 352 LtqqqvrPL----RREMQVVFQDP--FGSLSPR---MCVsqivgegLRIHKMgTEAEQEQAIIAALKEVGLDpETRHRYP 422
Cdd:COG1137    70 L------PMhkraRLGIGYLPQEAsiFRKLTVEdniLAV-------LELRKL-SKKEREERLEELLEEFGIT-HLRKSKA 134

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1834229548 423 HEFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:COG1137   135 YSLSGGERRRVEIARALATNPKFILLDEPFAGVD 168
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 7-189 1.72e-11

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 64.28  E-value: 1.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLkekT 86
Cdd:COG1137     4 LEAENLVKSY--GKR--TVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLV-----KPDSGRIFLDGEDITHL---P 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IrHIRGNR-IAMIFQEPmtslnplhSI------EKQINEVLGIHKgLIGKVATKRTLELLEMVGIpepEKRLKALPHELS 159
Cdd:COG1137    72 M-HKRARLgIGYLPQEA--------SIfrkltvEDNILAVLELRK-LSKKEREERLEELLEEFGI---THLRKSKAYSLS 138

                         170       180       190
                  ....*....|....*....|....*....|
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:COG1137   139 GGERRRVEIARALATNPKFILLDEPFAGVD 168
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 304-502 1.87e-11

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 63.26  E-value: 1.87e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GINFSLPQGQTLGIVGESGSGKSTLGLAIL----RLIGS---------------------KGGIRFeGKQLDSLTQQQVR 358
Cdd:cd03250    23 DINLEVPKGELVAIVGPVGSGKSSLLSALLgeleKLSGSvsvpgsiayvsqepwiqngtiRENILF-GKPFDEERYEKVI 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 359 P---LRREMQVVfqdPFGSLSprmcvsqIVGEglrihkmgteaeqeqaiiaalKEVGLdpetrhryphefSGGQRQRIAI 435
Cdd:cd03250   102 KacaLEPDLEIL---PDGDLT-------EIGE---------------------KGINL------------SGGQKQRISL 138

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 436 ARALVLKPALILLDEPTSALDRTVQRQVVE-LLRSLQSKyNLTYLFISHDLAVVKAlSHQLMVVKQGQ 502
Cdd:cd03250   139 ARAVYSDADIYLLDDPLSAVDAHVGRHIFEnCILGLLLN-NKTRILVTHQLQLLPH-ADQIVVLDNGR 204
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
23-246 1.96e-11

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 64.64  E-value: 1.96e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLlNLKEKTIRHIRgNRIAMIFQEP 102
Cdd:PRK13638   14 EPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLL-----RPQKGAVLWQGKPL-DYSKRGLLALR-QQVATVFQDP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 103 MTSLNpLHSIEKQIN---EVLGIHKGLIgkvaTKRTLELLEMVGipepEKRLKALPHE-LSGGQRQRVMIAMALANEPEL 178
Cdd:PRK13638   87 EQQIF-YTDIDSDIAfslRNLGVPEAEI----TRRVDEALTLVD----AQHFRHQPIQcLSHGQKKRVAIAGALVLQARY 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 179 LIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF 246
Cdd:PRK13638  158 LLLDEPTAGLDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 300-517 2.10e-11

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 64.14  E-value: 2.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 300 KAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQQVRPlRREMQVVFQDPfgSLSPRM 379
Cdd:PRK10895   17 RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARA-RRGIGYLPQEA--SIFRRL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 CVSQIVGEGLRIHKMGTEAEQEQAIIAALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTV 459
Cdd:PRK10895   94 SVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIE-HLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPIS 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 460 Q---RQVVELLRSlqskYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFAAPQ 517
Cdd:PRK10895  173 VidiKRIIEHLRD----SGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEH 229
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
294-512 3.86e-11

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 65.19  E-value: 3.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 294 KTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLI--GSKGGIRFEGKQLDSLTQQQVRPLrrEMQVVFQDp 371
Cdd:PRK09700   13 KSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTL-MKVLSGIhePTKGTITINNINYNKLDHKLAAQL--GIGIIYQE- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 fgslsprmcVSQI----VGEGLRIHKMGTE----------AEQEQAIIAALKEVGL--DPETRhryPHEFSGGQRQRIAI 435
Cdd:PRK09700   89 ---------LSVIdeltVLENLYIGRHLTKkvcgvniidwREMRVRAAMMLLRVGLkvDLDEK---VANLSISHKQMLEI 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 436 ARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:PRK09700  157 AKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDV 232
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 305-489 5.59e-11

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 65.44  E-value: 5.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQldSLTQQQVRPLRREMQVVFQDPF----------- 372
Cdd:PTZ00265   404 LNFTLTEGKTYAFVGESGCGKSTILKLIERLYDpTEGDIIINDSH--NLKDINLKWWRSKIGVVSQDPLlfsnsiknnik 481

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  373 -------------------------GSLSPRMCVSQIVGEGLRIHKMGT-----EAEQEQAIIAALKEVGLdpeTRHRYP 422
Cdd:PTZ00265   482 yslyslkdlealsnyynedgndsqeNKNKRNSCRAKCAGDLNDMSNTTDsneliEMRKNYQTIKDSEVVDV---SKKVLI 558

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  423 HEF-------------------SGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISH 483
Cdd:PTZ00265   559 HDFvsalpdkyetlvgsnasklSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAH 638


                   ....*.
gi 1834229548  484 DLAVVK 489
Cdd:PTZ00265   639 RLSTIR 644
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 12-236 6.59e-11

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 64.68  E-value: 6.59e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  12 LAVEFVVG---ERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKTIr 88
Cdd:TIGR01842 317 LSVENVTIvppGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPT-----SGSVRLDGADLKQWDRETF- 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  89 hirGNRIAMIFQEpmtslnplhsIEkqinevlgIHKGLIGKvatkrtlELLEMVGIPEPEKRLKALP----HE------- 157
Cdd:TIGR01842 391 ---GKHIGYLPQD----------VE--------LFPGTVAE-------NIARFGENADPEKIIEAAKlagvHElilrlpd 442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 ------------LSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKrIA 225
Cdd:TIGR01842 443 gydtvigpggatLSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKAR-GITVVVITHRPSLLG-CV 520

                         250
                  ....*....|.
gi 1834229548 226 HRVCVMQRGCI 236
Cdd:TIGR01842 521 DKILVLQDGRI 531
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
6-190 8.74e-11

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 61.36  E-value: 8.74e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   6 LIEVRDLAVEfvVGERcqRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNllnlkek 85
Cdd:PRK13538    1 MLEARNLACE--RDER--ILFSGLSFTLNAGELVQIEGPNGAGKT----SLLRILA-GLARPDAGEVLWQGEP------- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  86 tIRHIRGnriamIFQEPMTSLNPLHSIEKQIN--EVLGIHKGLIGKVATKRTLELLEMVGIpepEKRLKALPHELSGGQR 163
Cdd:PRK13538   65 -IRRQRD-----EYHQDLLYLGHQPGIKTELTalENLRFYQRLHGPGDDEALWEALAQVGL---AGFEDVPVRQLSAGQQ 135

                         170       180
                  ....*....|....*....|....*..
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDV 190
Cdd:PRK13538  136 RRVALARLWLTRAPLWILDEPFTAIDK 162
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 4-234 1.03e-10

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 64.08  E-value: 1.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFVVGERCQRVvEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplARHpSGTIeYSGQNLLNLK 83
Cdd:TIGR02633 255 DVILEARNLTCWDVINPHRKRV-DDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYP---GKF-EGNV-FINGKPVDIR 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  84 --EKTIRHirgnRIAMIfqepmtslnPLHSIEKQINEVLGIHKGLIGKVATK-----RTLELLEMVGIPEPEKRLKA--- 153
Cdd:TIGR02633 329 npAQAIRA----GIAMV---------PEDRKRHGIVPILGVGKNITLSVLKSfcfkmRIDAAAELQIIGSAIQRLKVkta 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 154 ---LP-HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVC 229
Cdd:TIGR02633 396 spfLPiGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQL-AQEGVAIIVVSSELAEVLGLSDRVL 474


                  ....*
gi 1834229548 230 VMQRG 234
Cdd:TIGR02633 475 VIGEG 479
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 34-497 1.29e-10

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 64.04  E-value: 1.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  34 KRGETLALVGESGSGKSvTAHSILrllpyplarhpsgtieySGQ---NLLNL-----KEKTIRHIRGNRIamifQEPMTS 105
Cdd:COG1245    97 KKGKVTGILGPNGIGKS-TALKIL-----------------SGElkpNLGDYdeepsWDEVLKRFRGTEL----QDYFKK 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 LnplhsIEKQINEVlgiHK----GLIGKVATKRTLELLEMVG----IPEPEKRLKaLPH-------ELSGGQRQRVMIAM 170
Cdd:COG1245   155 L-----ANGEIKVA---HKpqyvDLIPKVFKGTVRELLEKVDergkLDELAEKLG-LENildrdisELSGGELQRVAIAA 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 171 ALANEPELLIADEPTTALDVTvQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVM--QRGC--IVeqasceqlf 246
Cdd:COG1245   226 ALLRDADFYFFDEPSSYLDIY-QRLNVARLIRELAEEGKYVLVVEHDLAILDYLADYVHILygEPGVygVV--------- 295

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 247 rapQHPY-TRE--------LLAAE-----------PSGTPATNVVGPPMLTVEDLKVWFPikkgllkktvdyvkavdgiN 306
Cdd:COG1245   296 ---SKPKsVRVginqyldgYLPEEnvrirdepiefEVHAPRREKEEETLVEYPDLTKSYG-------------------G 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 307 FSLP-------QGQTLGIVGESGSGKSTLglaiLRLIGskGGIRFEGKQLD-----SLTQQQVRPlRREMQV------VF 368
Cdd:COG1245   354 FSLEveggeirEGEVLGIVGPNGIGKTTF----AKILA--GVLKPDEGEVDedlkiSYKPQYISP-DYDGTVeeflrsAN 426

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 QDPFGSlspRMCVSQIVgEGLRIHKMgteaeqeqaiiaalkevgLDpetrhRYPHEFSGGQRQRIAIARALvLKPA-LIL 447
Cdd:COG1245   427 TDDFGS---SYYKTEII-KPLGLEKL------------------LD-----KNVKDLSGGELQRVAIAACL-SRDAdLYL 478

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 448 LDEPTSALDrtV-QR-QVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMV 497
Cdd:COG1245   479 LDEPSAHLD--VeQRlAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMV 528
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
7-248 1.58e-10

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 63.58  E-value: 1.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSVTAHsiLRLLPYPLArhpSGTIEYSGQNLLNLKEKT 86
Cdd:PRK10790  341 IDIDNVSFAYRDD---NLVLQNINLSVPSRGFVALVGHTGSGKSTLAS--LLMGYYPLT---EGEIRLDGRPLSSLSHSV 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRhirgNRIAMIFQEPMTSLNPLHSiekqiNEVLGIHkglIGKVATKRTLE---LLEMV-GIPEP-EKRLKALPHELSGG 161
Cdd:PRK10790  413 LR----QGVAMVQQDPVVLADTFLA-----NVTLGRD---ISEEQVWQALEtvqLAELArSLPDGlYTPLGEQGNNLSVG 480

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 162 QRQRVMIAMALANEPELLIADEPTTALDVTVQlkilellkelQArLGMALLLISHDLNLVKrIAHR---------VCVMQ 232
Cdd:PRK10790  481 QKQLLALARVLVQTPQILILDEATANIDSGTE----------QA-IQQALAAVREHTTLVV-IAHRlstiveadtILVLH 548

                         250
                  ....*....|....*.
gi 1834229548 233 RGCIVEQASCEQLFRA 248
Cdd:PRK10790  549 RGQAVEQGTHQQLLAA 564
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 299-507 2.37e-10

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 62.76  E-value: 2.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGG-IRFEGKQLDSLTQQQVRPLrrEMQVVFQDPFgsLSP 377
Cdd:PRK15439   24 VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGtLEIGGNPCARLTPAKAHQL--GIYLVPQEPL--LFP 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIVGEGLRIHkmgteAEQEQAIIAALKEVGLdpetrHRYPHEFSG----GQRQRIAIARALVLKPALILLDEPTS 453
Cdd:PRK15439  100 NLSVKENILFGLPKR-----QASMQKMKQLLAALGC-----QLDLDSSAGslevADRQIVEILRGLMRDSRILILDEPTA 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 454 ALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:PRK15439  170 SLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIALSG 222
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 1-243 2.79e-10

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 60.81  E-value: 2.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEfvVGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpyplARHPS-----GTIEYS 75
Cdd:CHL00131    2 NKNKPILEIKNLHAS--VNEN--EILKGLNLSINKGEIHAIMGPNGSGKSTLSKVI--------AGHPAykileGDILFK 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  76 GQNLLNLkEKTIRHIRGnrIAMIFQEPMtslnplhsiekqinEVLGIHKGLIGKVA--TKRT---------LELLEMvgI 144
Cdd:CHL00131   70 GESILDL-EPEERAHLG--IFLAFQYPI--------------EIPGVSNADFLRLAynSKRKfqglpeldpLEFLEI--I 130

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 145 PEPEKRLKALPHEL--------SGGQRQRVMI-AMALAnEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLIS 215
Cdd:CHL00131  131 NEKLKLVGMDPSFLsrnvnegfSGGEKKRNEIlQMALL-DSELAILDETDSGLDIDALKIIAEGINKL-MTSENSIILIT 208

                         250       260
                  ....*....|....*....|....*....
gi 1834229548 216 HDLNLVKRIA-HRVCVMQRGCIVEQASCE 243
Cdd:CHL00131  209 HYQRLLDYIKpDYVHVMQNGKIIKTGDAE 237
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 298-489 3.80e-10

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 58.87  E-value: 3.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 298 YVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFegkqldsltqqqvRPLRREMQVVFQDpfgslsp 377
Cdd:cd03238     7 NVHNLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGLYASGKARLISF-------------LPKFSRNKLIFID------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 rmcvsqivgeglrihkmgteaeQEQAIIaalkEVGLDPETRHRYPHEFSGGQRQRIAIARALV--LKPALILLDEPTSAL 455
Cdd:cd03238    67 ----------------------QLQFLI----DVGLGYLTLGQKLSTLSGGELQRVKLASELFsePPGTLFILDEPSTGL 120

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1834229548 456 DRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVK 489
Cdd:cd03238   121 HQQDINQLLEVIKGLIDLGN-TVILIEHNLDVLS 153
hmuV PRK13547
heme ABC transporter ATP-binding protein;
302-532 3.96e-10

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 60.61  E-value: 3.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTL---------GLAILRLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPF 372
Cdd:PRK13547   17 LRDLSLRIEPGRVTALLGRNGAGKSTLlkalagdltGGGAPRGARVTGDVTLNGEPLAAIDAPRLARLRAVLPQAAQPAF 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 GslsprMCVSQIVGEGLRIH--KMGTEAEQEQAII-AALKEVGLDPETRhRYPHEFSGGQRQRIAIARAL---------V 440
Cdd:PRK13547   97 A-----FSAREIVLLGRYPHarRAGALTHRDGEIAwQALALAGATALVG-RDVTTLSGGELARVQFARVLaqlwpphdaA 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 441 LKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGdaqsifaAPQHPY 520
Cdd:PRK13547  171 QPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHG-------APADVL 243

                         250
                  ....*....|..
gi 1834229548 521 TQQLLEAAFLVP 532
Cdd:PRK13547  244 TPAHIARCYGFA 255
GguA NF040905
sugar ABC transporter ATP-binding protein;
294-505 3.97e-10

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 62.11  E-value: 3.97e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 294 KTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLI---GS-KGGIRFEGKQldsltqQQVRPLR----REMQ 365
Cdd:NF040905    9 KTFPGVKALDDVNLSVREGEIHALCGENGAGKSTL-MKVLSGVyphGSyEGEILFDGEV------CRFKDIRdseaLGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 366 VVFQDPfgSLSPRMCVSQIVGEGLRIHKMG----TEAEQEQAiiAALKEVGLD--PETRhryPHEFSGGQRQRIAIARAL 439
Cdd:NF040905   82 IIHQEL--ALIPYLSIAENIFLGNERAKRGvidwNETNRRAR--ELLAKVGLDesPDTL---VTDIGVGKQQLVEIAKAL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 440 VLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVE 505
Cdd:NF040905  155 SKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTIE 219
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 305-532 4.56e-10

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 60.33  E-value: 4.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQ-----------QQVRPLrremqvvfqdpfg 373
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPGSGSIQFAGQPLEAWSAaelarhraylsQQQTPP------------- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 slsPRMCVSQIvgegLRIHkmGTEAEQEQAIIAALKEV----GLDPETrHRYPHEFSGGQRQRIAIARAL-----VLKPA 444
Cdd:PRK03695   82 ---FAMPVFQY----LTLH--QPDKTRTEAVASALNEVaealGLDDKL-GRSVNQLSGGEWQRVRLAAVVlqvwpDINPA 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 445 --LILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFaapqhpyTQ 522
Cdd:PRK03695  152 gqLLLLDEPMNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVL-------TP 223

                         250
                  ....*....|
gi 1834229548 523 QLLEAAFLVP 532
Cdd:PRK03695  224 ENLAQVFGVN 233
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
303-470 5.22e-10

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 59.05  E-value: 5.22e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGS-----KGGIRFEGkqldsltqqqvRPLRREMQVVFQDPF----- 372
Cdd:PRK13538   18 SGLSFTLNAGELVQIEGPNGAGKTSL----LRILAGlarpdAGEVLWQG-----------EPIRRQRDEYHQDLLylghq 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 ----GSLSPRmcvsqivgEGLRI-HKMGTEAEQEqAIIAALKEVGLdpETRHRYP-HEFSGGQRQRIAIARALVLKPALI 446
Cdd:PRK13538   83 pgikTELTAL--------ENLRFyQRLHGPGDDE-ALWEALAQVGL--AGFEDVPvRQLSAGQQRRVALARLWLTRAPLW 151

                         170       180
                  ....*....|....*....|....
gi 1834229548 447 LLDEPTSALDrtvqRQVVELLRSL 470
Cdd:PRK13538  152 ILDEPFTAID----KQGVARLEAL 171
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
29-250 5.23e-10

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 61.20  E-value: 5.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIeYSGQNLLNLKEKTIRHIrgnriAMIFQEpmTSLNP 108
Cdd:PRK11000   22 INLDIHEGEFVVFVGPSGCGKS----TLLRMIA-GLEDITSGDL-FIGEKRMNDVPPAERGV-----GMVFQS--YALYP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 LHSIEKqiNEVLGIHKGLIGKVATKRTLEllEMVGIPEPEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTAL 188
Cdd:PRK11000   89 HLSVAE--NMSFGLKLAGAKKEEINQRVN--QVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNL 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 189 DVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQ 250
Cdd:PRK11000  165 DAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPA 226
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1-238 5.53e-10

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 61.72  E-value: 5.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAvefvvgERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpYPLARHPSGTIEYSGQNL- 79
Cdd:PRK09700  260 LAHETVFEVRNVT------SRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCL-----FGVDKRAGGEIRLNGKDIs 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  80 ----LNLKEKTIRHIRGNRIAMIFQePMTSLNPLHSIEKQINevLGIHKGLIGKVATKRTLEllemvgIPEPEKRLKALP 155
Cdd:PRK09700  329 prspLDAVKKGMAYITESRRDNGFF-PNFSIAQNMAISRSLK--DGGYKGAMGLFHEVDEQR------TAENQRELLALK 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 --------HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHR 227
Cdd:PRK09700  400 chsvnqniTELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQL-ADDGKVILMVSSELPEIITVCDR 478

                         250
                  ....*....|.
gi 1834229548 228 VCVMQRGCIVE 238
Cdd:PRK09700  479 IAVFCEGRLTQ 489
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
5-245 5.84e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 60.90  E-value: 5.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFvvGErcQRVVEGVSFDIKRGETLALVGESGSGKSVTAhsilrlLPYPLARHPSGTIEYSGQNLLNLKE 84
Cdd:NF000106   12 NAVEVRGLVKHF--GE--VKAVDGVDLDVREGTVLGVLGP*GAA**RGA------LPAHV*GPDAGRRPWRF*TWCANRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  85 KTIRHIRGNR-IAMIFQEPMTSLNPLHSIEKQINevlgihkgLIGKVATKRTLELLEMVGIPEPEKRLKAlphELSGGQR 163
Cdd:NF000106   82 ALRRTIG*HRpVR*GRRESFSGRENLYMIGR*LD--------LSRKDARARADELLERFSLTEAAGRAAA---KYSGGMR 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 164 QRVMIAMALANEPELLIADEPTTALDVTVQlKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCE 243
Cdd:NF000106  151 RRLDLAASMIGRPAVLYLDEPTTGLDPRTR-NEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVD 229


                  ..
gi 1834229548 244 QL 245
Cdd:NF000106  230 EL 231
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 289-512 6.49e-10

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 61.44  E-value: 6.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 289 KGLLKKTVD--YVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRL-IGSKGGIRFEGKQldsltqqqvrplrrEMQ 365
Cdd:PRK13545   25 KDLFFRSKDgeYHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVtMPNKGTVDIKGSA--------------ALI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 366 VVFQDPFGSLSPrmcVSQIVGEGLRihkMGTEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPAL 445
Cdd:PRK13545   91 AISSGLNGQLTG---IENIELKGLM---MGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDI 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSI 512
Cdd:PRK13545  165 LVIDEALSVGDQTFTKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV 230
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 292-517 7.46e-10

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 59.34  E-value: 7.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTV-DYVKAVDGINFSlpQGQTLGIVGESGSGKSTLglaiLRLIGskGGIR-FEGKQLDSLTQQQVRPlrREMQVVFQ 369
Cdd:cd03237     6 MKKTLgEFTLEVEGGSIS--ESEVIGILGPNGIGKTTF----IKMLA--GVLKpDEGDIEIELDTVSYKP--QYIKADYE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 370 dpfgslsprMCVSQIVGEGLRIHkmGTEAEQEQAIIAALK-EVGLDPETRhryphEFSGGQRQRIAIArALVLKPA-LIL 447
Cdd:cd03237    76 ---------GTVRDLLSSITKDF--YTHPYFKTEIAKPLQiEQILDREVP-----ELSGGELQRVAIA-ACLSKDAdIYL 138

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 448 LDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVkQGQVVEQGDAqsifAAPQ 517
Cdd:cd03237   139 LDEPSAYLDVEQRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIVF-EGEPSVNGVA----NPPQ 203
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 1-248 1.00e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 60.79  E-value: 1.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEV---RDLA-----VEFVVGERCQRV-------VEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLA 65
Cdd:PRK10762  228 LTEDSLIEMmvgRKLEdqyprLDKAPGEVRLKVdnlsgpgVNDVSFTLRKGEILGVSGLMGAGRT----ELMKVLYGALP 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  66 RHpSGTIEYSGQNLLNLKEKT-----IRHIRGNR------IAMIFQEPM--TSLNPLHSIEKQINevlgiHKGLIGKVAt 132
Cdd:PRK10762  304 RT-SGYVTLDGHEVVTRSPQDglangIVYISEDRkrdglvLGMSVKENMslTALRYFSRAGGSLK-----HADEQQAVS- 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 133 krtlELLEMVGI--PEPEKRLKalphELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMA 210
Cdd:PRK10762  377 ----DFIRLFNIktPSMEQAIG----LLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLS 447

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1834229548 211 LLLISHDLNLVKRIAHRVCVMQRGCI-----VEQASCEQLFRA 248
Cdd:PRK10762  448 IILVSSEMPEVLGMSDRILVMHEGRIsgeftREQATQEKLMAA 490
PLN03073 PLN03073
ABC transporter F family; Provisional
 403-483 1.09e-09

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 61.03  E-value: 1.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 403 AIIAALKevgLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDrtvqRQVVELLRSLQSKYNLTYLFIS 482
Cdd:PLN03073  326 SILAGLS---FTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD----LHAVLWLETYLLKWPKTFIVVS 398


                  .
gi 1834229548 483 H 483
Cdd:PLN03073  399 H 399
PLN03130 PLN03130
ABC transporter C family member; Provisional
 304-505 1.24e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 61.29  E-value: 1.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  304 GINFSLPQGQTLGIVGESGSGKSTLGLAILRLIG-SKGGIRFEGKQLDSLTqqqVRPLRREMQVVFQDPfgslsprMCVS 382
Cdd:PLN03130  1257 GLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVElERGRILIDGCDISKFG---LMDLRKVLGIIPQAP-------VLFS 1326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  383 QIVGEGLRIHKMGTEAEQEQAIIAA-LKEV------GLDPETRHRyPHEFSGGQRQRIAIARALVLKPALILLDEPTSAL 455
Cdd:PLN03130  1327 GTVRFNLDPFNEHNDADLWESLERAhLKDVirrnslGLDAEVSEA-GENFSVGQRQLLSLARALLRRSKILVLDEATAAV 1405

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548  456 D-RT---VQRQVVELLRSlqskynLTYLFISHDLAVVKAlSHQLMVVKQGQVVE 505
Cdd:PLN03130  1406 DvRTdalIQKTIREEFKS------CTMLIIAHRLNTIID-CDRILVLDAGRVVE 1452
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 303-504 1.42e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 60.73  E-value: 1.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 303 DGINFSLPQGQTLGIVGESGSGKSTLgLAIL--RLIGSKGGIRFEGKQLDSLTQQQvrPLRREMQVVFQDPFGSLsprmc 380
Cdd:PRK11147   20 DNAELHIEDNERVCLVGRNGAGKSTL-MKILngEVLLDDGRIIYEQDLIVARLQQD--PPRNVEGTVYDFVAEGI----- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 381 vsQIVGEGLRI-----HKMGTEAE----------QEQ-----------AIIAALKEVGLDPETRHRyphEFSGGQRQRIA 434
Cdd:PRK11147   92 --EEQAEYLKRyhdisHLVETDPSeknlnelaklQEQldhhnlwqlenRINEVLAQLGLDPDAALS---SLSGGWLRKAA 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 435 IARALVLKPALILLDEPTSALDRTvqrqVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:PRK11147  167 LGRALVSNPDVLLLDEPTNHLDIE----TIEWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLV 232
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 299-485 1.54e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 60.40  E-value: 1.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLIGSK--GGIRFEGKQ-----------------------LDSLT 353
Cdd:PRK10762   17 VKALSGAALNVYPGRVMALVGENGAGKSTM-MKVLTGIYTRdaGSILYLGKEvtfngpkssqeagigiihqelnlIPQLT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 354 QQQVRPLRREmqvvFQDPFGSLSPRmcvsqivgeglrihKMGTEAEqeqaiiAALKEVGLdPETRHRYPHEFSGGQRQRI 433
Cdd:PRK10762   96 IAENIFLGRE----FVNRFGRIDWK--------------KMYAEAD------KLLARLNL-RFSSDKLVGELSIGEQQMV 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 434 AIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDL 485
Cdd:PRK10762  151 EIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRL 201
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
138-253 1.61e-09

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 59.50  E-value: 1.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 138 LLEMVGIpepEKRLKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHD 217
Cdd:PRK11144  112 IVALLGI---EPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPILYVSHS 188

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1834229548 218 LNLVKRIAHRVCVMQRGCIVEQASCEQLFRAPQ-HPY 253
Cdd:PRK11144  189 LDEILRLADRVVVLEQGKVKAFGPLEEVWASSAmRPW 225
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 29-503 1.75e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 60.13  E-value: 1.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLlnlKEKTIRHIRGNRIAMIFQEpmtsLNP 108
Cdd:PRK10982   17 VNLKVRPHSIHALMGENGAGKS----TLLKCL-FGIYQKDSGSILFQGKEI---DFKSSKEALENGISMVHQE----LNL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 LHSIEKQINEVLGIH--KGLI--GKVATKRTLELLEMVGIP-EPEKRLKalphELSGGQRQRVMIAMALANEPELLIADE 183
Cdd:PRK10982   85 VLQRSVMDNMWLGRYptKGMFvdQDKMYRDTKAIFDELDIDiDPRAKVA----TLSVSQMQMIEIAKAFSYNAKIVIMDE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 184 PTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGciveqasceqlfrapQHPYTRELlaaepS 263
Cdd:PRK10982  161 PTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDG---------------QWIATQPL-----A 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 264 GTPATNVVGppMLTVEDLKVWFPIKKGLLKKTVDYVK--------AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRL 335
Cdd:PRK10982  220 GLTMDKIIA--MMVGRSLTQRFPDKENKPGEVILEVRnltslrqpSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGI 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 336 IGSKGG-IRFEGKQLDSLTQQQ--------VRPLRREMQVV----------------FQDPFGSLSPRMCVS--QIVgeg 388
Cdd:PRK10982  298 REKSAGtITLHGKKINNHNANEainhgfalVTEERRSTGIYayldigfnslisnirnYKNKVGLLDNSRMKSdtQWV--- 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 389 lrIHKMGTEAEQEQAIIAALkevgldpetrhryphefSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLR 468
Cdd:PRK10982  375 --IDSMRVKTPGHRTQIGSL-----------------SGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA 435

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 1834229548 469 SLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:PRK10982  436 ELAKK-DKGIIIISSEMPELLGITDRILVMSNGLV 469
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 25-248 1.86e-09

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 60.15  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyPLarhpSGTIEYSGQNLlnlkektirhirgnriamifqepmT 104
Cdd:COG4618   347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWP-PT----AGSVRLDGADL------------------------S 397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 105 SLNPlhsiekqinEVLGIHkglIGKVAtkRTLELLE--------MVGIPEPEKRLKA------------LP--------- 155
Cdd:COG4618   398 QWDR---------EELGRH---IGYLP--QDVELFDgtiaeniaRFGDADPEKVVAAaklagvhemilrLPdgydtrige 463

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 --HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVkRIAHRVCVMQR 233
Cdd:COG4618   464 ggARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPSLL-AAVDKLLVLRD 541

                         250
                  ....*....|....*
gi 1834229548 234 GCIVEQASCEQLFRA 248
Cdd:COG4618   542 GRVQAFGPRDEVLAR 556
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 273-470 1.88e-09

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 57.25  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 273 PPMLTVEDLKVWFPIKKG---LLKKTVDYVKAvdginfslpqGQTLGIVGESGSGKSTL--GLAILRLIGS-KGGIRFEG 346
Cdd:cd03232     1 GSVLTWKNLNYTVPVKGGkrqLLNNISGYVKP----------GTLTALMGESGAGKTTLldVLAGRKTAGViTGEILING 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 347 KQLDSltqqqvrPLRREMQVVFQDPFgsLSPrmcvSQIVGEGLRIHkmgteaeqeqaiiAALKevGLDPEtrhryphefs 426
Cdd:cd03232    71 RPLDK-------NFQRSTGYVEQQDV--HSP----NLTVREALRFS-------------ALLR--GLSVE---------- 112

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1834229548 427 ggQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSL 470
Cdd:cd03232   113 --QRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKL 154
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 28-189 1.98e-09

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 60.06  E-value: 1.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSvTAHSILrllpypLARHPSGTiEYSGQNLLNLKEKTIRHIRgNRIAMIFQEPM---- 103
Cdd:TIGR00955  43 NVSGVAKPGELLAVMGSSGAGKT-TLMNAL------AFRSPKGV-KGSGSVLLNGMPIDAKEMR-AISAYVQQDDLfipt 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 104 -TSLNPLhsiekQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHE---LSGGQRQRVMIAMALANEPELL 179
Cdd:TIGR00955 114 lTVREHL-----MFQAHLRMPRRVTKKEKRERVDEVLQALGLRKCANTRIGVPGRvkgLSGGERKRLAFASELLTDPPLL 188

                         170
                  ....*....|
gi 1834229548 180 IADEPTTALD 189
Cdd:TIGR00955 189 FCDEPTSGLD 198
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 311-484 2.63e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.84  E-value: 2.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  311 QGQTLGIVGESGSGKSTLGLAILRLIGSKGGirfegkqldsltqqqvrplrremQVVFQDPfgslsprmcvsqivgeglr 390
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGG-----------------------GVIYIDG------------------- 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  391 ihkmgteaeqeqAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRS- 469
Cdd:smart00382  39 ------------EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELr 106

                          170
                   ....*....|....*....
gi 1834229548  470 ----LQSKYNLTYLFISHD 484
Cdd:smart00382 107 llllLKSEKNLTVILTTND 125
PLN03130 PLN03130
ABC transporter C family member; Provisional
 305-528 9.12e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 58.60  E-value: 9.12e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIG--SKGGIRFEGK-----QLDSLTQQQVRPlrremQVVFQDPFGSlsp 377
Cdd:PLN03130   636 INLDVPVGSLVAIVGSTGEGKTSLISAMLGELPprSDASVVIRGTvayvpQVSWIFNATVRD-----NILFGSPFDP--- 707

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  378 rmcvsqivgeglrihkmgteAEQEQAI-IAALK-EVGLDPETRHRYPHE----FSGGQRQRIAIARALVLKPALILLDEP 451
Cdd:PLN03130   708 --------------------ERYERAIdVTALQhDLDLLPGGDLTEIGErgvnISGGQKQRVSMARAVYSNSDVYIFDDP 767

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  452 TSALDRTVQRQVVE--LLRSLQSKynlTYLFISHDLAVvkaLSH--QLMVVKQGQVVEQGDAQSIFAapQHPYTQQLLEA 527
Cdd:PLN03130   768 LSALDAHVGRQVFDkcIKDELRGK---TRVLVTNQLHF---LSQvdRIILVHEGMIKEEGTYEELSN--NGPLFQKLMEN 839


                   .
gi 1834229548  528 A 528
Cdd:PLN03130   840 A 840
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
 305-507 1.06e-08

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 56.08  E-value: 1.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAIL------RLIGSKG----GIRFEG-KQLDSLTqqqvrplrremqVVFQDPFG 373
Cdd:cd03271    14 IDVDIPLGVLTCVTGVSGSGKSSLINDTLypalarRLHLKKEqpgnHDRIEGlEHIDKVI------------VIDQSPIG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 374 SlSPRMC---------------------------VSQIVGEGLRIH---KMGTEAEQE--------QAIIAALKEVGLDP 415
Cdd:cd03271    82 R-TPRSNpatytgvfdeirelfcevckgkrynreTLEVRYKGKSIAdvlDMTVEEALEffenipkiARKLQTLCDVGLGY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 416 ETRHRYPHEFSGGQRQRIAIARALvLKPA----LILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKAL 491
Cdd:cd03271   161 IKLGQPATTLSGGEAQRIKLAKEL-SKRStgktLYILDEPTTGLHFHDVKKLLEVLQRLVDKGN-TVVVIEHNLDVIKCA 238

                         250       260
                  ....*....|....*....|.
gi 1834229548 492 SHQLMV-----VKQGQVVEQG 507
Cdd:cd03271   239 DWIIDLgpeggDGGGQVVASG 259
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 312-484 1.28e-08

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 57.49  E-value: 1.28e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 312 GQTLGIVGESGSGKSTLgLAILR--LIGSKGGIRFEGKQLDSLTQQQVRPLRR---EMQVVFQDPFGSLSPRMCVSQIVG 386
Cdd:PRK10636   27 GQKVGLVGKNGCGKSTL-LALLKneISADGGSYTFPGNWQLAWVNQETPALPQpalEYVIDGDREYRQLEAQLHDANERN 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 387 EGlriHKMGTEAEQEQAIIA---------ALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDR 457
Cdd:PRK10636  106 DG---HAIATIHGKLDAIDAwtirsraasLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDL 182

                         170       180
                  ....*....|....*....|....*..
gi 1834229548 458 TVqrqVVELLRSLQSkYNLTYLFISHD 484
Cdd:PRK10636  183 DA---VIWLEKWLKS-YQGTLILISHD 205
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 292-484 1.49e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 57.25  E-value: 1.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAV-DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGskgGI--RFEGKqldsltqqqVRPlRREMQVVF 368
Cdd:TIGR03719  10 VSKVVPPKKEIlKDISLSFFPGAKIGVLGLNGAGKSTL----LRIMA---GVdkDFNGE---------ARP-QPGIKVGY 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 369 --QDPfgSLSPRMCVSQIVGEGLR----------------------IHKMGTEAEQEQAIIAALK--------EVGLDPe 416
Cdd:TIGR03719  73 lpQEP--QLDPTKTVRENVEEGVAeikdaldrfneisakyaepdadFDKLAAEQAELQEIIDAADawdldsqlEIAMDA- 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 417 trHRYP------HEFSGGQRQRIAIARALVLKPALILLDEPTSALDrtvQRQVVELLRSLQsKYNLTYLFISHD 484
Cdd:TIGR03719 150 --LRCPpwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD---AESVAWLERHLQ-EYPGTVVAVTHD 217
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 305-465 1.56e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 57.61  E-value: 1.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  305 INFSLPQGQTLGIVGESGSGKSTLGLAIL-RLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQ 383
Cdd:TIGR01271  445 ISFKLEKGQLLAVAGSTGSGKSSLLMMIMgELEPSEGKIKHSGRISFSPQTSWIMPGTIKDNIIFGLSYDEYRYTSVIKA 524

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  384 IVGEglriHKMGTEAEQEQAIiaaLKEVGLdpetrhryphEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQV 463
Cdd:TIGR01271  525 CQLE----EDIALFPEKDKTV---LGEGGI----------TLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTEKEI 587


                   ..
gi 1834229548  464 VE 465
Cdd:TIGR01271  588 FE 589
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 25-234 1.67e-08

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 54.78  E-value: 1.67e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarHPSGTIEYSG------QN--LLNlkektiRHIRGNria 96
Cdd:cd03250    20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELE-----KLSGSVSVPGsiayvsQEpwIQN------GTIREN--- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  97 MIFQEPMtslnplhsIEKQINEVLgihkgligKV-ATKRTLELLE-----MVGipepEKRLKalpheLSGGQRQRVMIAM 170
Cdd:cd03250    86 ILFGKPF--------DEERYEKVI--------KAcALEPDLEILPdgdltEIG----EKGIN-----LSGGQKQRISLAR 140

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 171 ALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRG 234
Cdd:cd03250   141 AVYSDADIYLLDDPLSAVDAHVGRHIFENCILGLLLNNKTRILVTHQLQLLPH-ADQIVVLDNG 203
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 302-483 1.83e-08

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 57.07  E-value: 1.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGS----KGGIRFegkqldsltqqqvRPLRREMQVVFQDPFGSLsp 377
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSL----FRILGElwpvYGGRLT-------------KPAKGKLFYVPQRPYMTL-- 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 378 RMCVSQIvgeglrIHKMGTEAEQ-----EQAIIAALKEVGLDP--------ETRHRYPHEFSGGQRQRIAIARALVLKPA 444
Cdd:TIGR00954 529 GTLRDQI------IYPDSSEDMKrrglsDKDLEQILDNVQLTHilereggwSAVQDWMDVLSGGEKQRIAMARLFYHKPQ 602

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1834229548 445 LILLDEPTSALDRTVQRQVVELLRslqsKYNLTYLFISH 483
Cdd:TIGR00954 603 FAILDECTSAVSVDVEGYMYRLCR----EFGITLFSVSH 637
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 301-507 1.96e-08

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 57.33  E-value: 1.96e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  301 AVDGINFSLPQGQTLGIVGESGSGKSTLgLAILR--LIGSKGGIRFEGKQLDSltqqQVRPLRREMQVVFQDP--FGSLS 376
Cdd:TIGR01257  945 AVDRLNITFYENQITAFLGHNGAGKTTT-LSILTglLPPTSGTVLVGGKDIET----NLDAVRQSLGMCPQHNilFHHLT 1019

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  377 prmcvsqiVGEGLRIHKMGTEAEQEQAII---AALKEVGLDpETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTS 453
Cdd:TIGR01257 1020 --------VAEHILFYAQLKGRSWEEAQLemeAMLEDTGLH-HKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTS 1090

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548  454 ALDRTVQRQVVELLrsLQSKYNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQG 507
Cdd:TIGR01257 1091 GVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSG 1142
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 302-484 1.96e-08

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 57.05  E-value: 1.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 302 VDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGSK-----GGIRF-EGKQLDSLTQQqvrplrREmqvvfqdpfgSL 375
Cdd:PRK11819  340 IDDLSFSLPPGGIVGIIGPNGAGKSTL----FKMITGQeqpdsGTIKIgETVKLAYVDQS------RD----------AL 399

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SPRMCVSQIVGEGLRIHKMGTEAEQEQAIIAAL--------KEVGldpetrhryphEFSGGQRQRIAIARALVLKPALIL 447
Cdd:PRK11819  400 DPNKTVWEEISGGLDIIKVGNREIPSRAYVGRFnfkggdqqKKVG-----------VLSGGERNRLHLAKTLKQGGNVLL 468

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1834229548 448 LDEPTSALDrtvqrqvVELLRSLQS---KYNLTYLFISHD 484
Cdd:PRK11819  469 LDEPTNDLD-------VETLRALEEallEFPGCAVVISHD 501
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 305-465 3.18e-08

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 55.25  E-value: 3.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLAIL-RLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLSPRMCVSQ 383
Cdd:cd03291    56 INLKIEKGEMLAITGSTGSGKTSLLMLILgELEPSEGKIKHSGRISFSSQFSWIMPGTIKENIIFGVSYDEYRYKSVVKA 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 384 IVGEglriHKMGTEAEQEQAIIAalkEVGLDpetrhrypheFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQV 463
Cdd:cd03291   136 CQLE----EDITKFPEKDNTVLG---EGGIT----------LSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEI 198


                  ..
gi 1834229548 464 VE 465
Cdd:cd03291   199 FE 200
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 299-504 4.02e-08

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 55.89  E-value: 4.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLgLAILRLIGSK--GGIRFEGKQLDSLTQQQ-----VRPLRREMQVVFQDp 371
Cdd:PRK10982   11 VKALDNVNLKVRPHSIHALMGENGAGKSTL-LKCLFGIYQKdsGSILFQGKEIDFKSSKEalengISMVHQELNLVLQR- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 372 fgSLSPRMCVSQIVGEGLRI--HKMGTEAEqeqaiiAALKEVGLDPETRHRYPhEFSGGQRQRIAIARALVLKPALILLD 449
Cdd:PRK10982   89 --SVMDNMWLGRYPTKGMFVdqDKMYRDTK------AIFDELDIDIDPRAKVA-TLSVSQMQMIEIAKAFSYNAKIVIMD 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 450 EPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVV 504
Cdd:PRK10982  160 EPTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQWI 213
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 25-231 4.45e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 56.19  E-value: 4.45e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYpLARHPSGTIEYSGQNllNLKEKTIRHIRgNRIAMIFQEPMT 104
Cdd:PTZ00265   400 IYKDLNFTLTEGKTYAFVGESGCGKS----TILKLIER-LYDPTEGDIIINDSH--NLKDINLKWWR-SKIGVVSQDPLL 471

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  105 --------------SLNPLHSIEKQINE------------------VLGIHKGLI------GKVATKRTLELLEMVGIPE 146
Cdd:PTZ00265   472 fsnsiknnikyslySLKDLEALSNYYNEdgndsqenknkrnscrakCAGDLNDMSnttdsnELIEMRKNYQTIKDSEVVD 551

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  147 PEKRL------KALP-----------HELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARLGM 209
Cdd:PTZ00265   552 VSKKVlihdfvSALPdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENR 631

                          250       260
                   ....*....|....*....|..
gi 1834229548  210 ALLLISHDLNLVkRIAHRVCVM 231
Cdd:PTZ00265   632 ITIIIAHRLSTI-RYANTIFVL 652
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
307-498 4.55e-08

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 55.59  E-value: 4.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 307 FSLP---QGQTLGIVGESGSGKSTLgLAIL--RLI---------GSKGGI--RFEGKQL----DSLTQQQVRPLRReMQV 366
Cdd:PRK13409   91 YGLPipkEGKVTGILGPNGIGKTTA-VKILsgELIpnlgdyeeePSWDEVlkRFRGTELqnyfKKLYNGEIKVVHK-PQY 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgslsprMCVSQIVGEGLRihkmgtEAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALvLKPALI 446
Cdd:PRK13409  169 VDLIP-------KVFKGKVRELLK------KVDERGKLDEVVERLGLEN-ILDRDISELSGGELQRVAIAAAL-LRDADF 233

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1834229548 447 -LLDEPTSALDrTVQR-QVVELLRSLQSKYNLtyLFISHDLAVVKALSHQLMVV 498
Cdd:PRK13409  234 yFFDEPTSYLD-IRQRlNVARLIRELAEGKYV--LVVEHDLAVLDYLADNVHIA 284
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 291-507 5.02e-08

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 53.42  E-value: 5.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 291 LLKKTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSK----GGIRFEGKQLDSLTQQQVRplrremQV 366
Cdd:cd03233    12 TTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsveGDIHYNGIPYKEFAEKYPG------EI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFqdpfgslsprmcVSQivgEGLRIHKMGTEaeqeQAIIAALKEVGldpetrHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03233    86 IY------------VSE---EDVHFPTLTVR----ETLDFALRCKG------NEFVRGISGGERKRVSIAEALVSRASVL 140

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNLTyLFISHDLAVVKALS--HQLMVVKQGQVVEQG 507
Cdd:cd03233   141 CWDNSTRGLDSSTALEILKCIRTMADVLKTT-TFVSLYQASDEIYDlfDKVLVLYEGRQIYYG 202
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 1-189 5.03e-08

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 53.56  E-value: 5.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDlaVEFVVGERcqRVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPYPlarhPSGTIEYSGQNLL 80
Cdd:PRK10247    2 QENSPLLQLQN--VGYLAGDA--KILNNISFSLRAGEFKLITGPSGCGKS-TLLKIVASLISP----TSGTLLFEGEDIS 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 NLKEKTIRHirgnRIAMIFQEPM----TSLNPL---HSIEKQinevlgihkgligKVATKRTLELLEMVGIPEP--EKRL 151
Cdd:PRK10247   73 TLKPEIYRQ----QVSYCAQTPTlfgdTVYDNLifpWQIRNQ-------------QPDPAIFLDDLERFALPDTilTKNI 135

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1834229548 152 kalpHELSGGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:PRK10247  136 ----AELSGGEKQRISLIRNLQFMPKVLLLDEITSALD 169
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 302-514 5.08e-08

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 56.11  E-value: 5.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  302 VDGINFSLPQGQTLGIVGESGSGKSTLGLAIL-RLIGSKGGIRFEGKQLDSLTQQQVRPLRREMQVVFQDPfgsLSPRMC 380
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLaEMDKVEGHVHMKGSVAYVPQQAWIQNDSLRENILFGKA---LNEKYY 730

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  381 VSQIVG----EGLRIHKMGTEAEqeqaiiaaLKEVGLDpetrhrypheFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:TIGR00957  731 QQVLEAcallPDLEILPSGDRTE--------IGEKGVN----------LSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 792

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548  457 RTVQRQVVE-LLRSLQSKYNLTYLFISHDLAVVKALSHqLMVVKQGQVVEQGDAQSIFA 514
Cdd:TIGR00957  793 AHVGKHIFEhVIGPEGVLKNKTRILVTHGISYLPQVDV-IIVMSGGKISEMGSYQELLQ 850
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 307-492 6.47e-08

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 53.91  E-value: 6.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 307 FSLP---QGQTLGIVGESGSGKSTlGLAIL--RLIGSKGGIR-----------FEGKQL----DSLTQQQVRPLRREmQV 366
Cdd:cd03236    18 HRLPvprEGQVLGLVGPNGIGKST-ALKILagKLKPNLGKFDdppdwdeildeFRGSELqnyfTKLLEGDVKVIVKP-QY 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 367 VFQDPfgslsprmcvSQIVGEGLRIHKMGTEAEQEQAIIAALkevGLDPeTRHRYPHEFSGGQRQRIAIARALVLKPALI 446
Cdd:cd03236    96 VDLIP----------KAVKGKVGELLKKKDERGKLDELVDQL---ELRH-VLDRNIDQLSGGELQRVAIAAALARDADFY 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1834229548 447 LLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKALS 492
Cdd:cd03236   162 FFDEPSSYLDIKQRLNAARLIRELAEDDN-YVLVVEHDLAVLDYLS 206
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
158-456 6.80e-08

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 55.52  E-value: 6.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALANEPELLIADEPTTALD-----------VTVQlkilellkelQARLGMALLLISHDLNLVKRIAH 226
Cdd:NF033858  137 LSGGMKQKLGLCCALIHDPDLLILDEPTTGVDplsrrqfweliDRIR----------AERPGMSVLVATAYMEEAERFDW 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 227 RVcVMQRGCIVEQASCEQLFRAPQHP-----YTReLLAAEPSGTPATNVVGPPMLTVEDLKVwfpIK-KGLLKKTVDYVk 300
Cdd:NF033858  207 LV-AMDAGRVLATGTPAELLARTGADtleaaFIA-LLPEEKRRGHQPVVIPPRPADDDDEPA---IEaRGLTMRFGDFT- 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTL-----GLailrLIGSKGGIRFEGKQLDSltqqqvrplrremqvvfqdpfGSL 375
Cdd:NF033858  281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTmkmltGL----LPASEGEAWLFGQPVDA---------------------GDI 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 376 SPRMCV---SQ--------IVGEGLRIH----KMGtEAEQEQAIIAALKEVGLDPETRHRyPHEFSGGQRQRIAIARALV 440
Cdd:NF033858  336 ATRRRVgymSQafslygelTVRQNLELHarlfHLP-AAEIAARVAEMLERFDLADVADAL-PDSLPLGIRQRLSLAVAVI 413

                         330
                  ....*....|....*.
gi 1834229548 441 LKPALILLDEPTSALD 456
Cdd:NF033858  414 HKPELLILDEPTSGVD 429
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 426-502 9.50e-08

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 52.61  E-value: 9.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 426 SGGQRQ------RIAIARALVLKPALILLDEPTSALDR-TVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVV 498
Cdd:cd03240   117 SGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEeNIEESLAEIIEERKSQKNFQLIVITHDEELVDAADHIYRVE 196


                  ....
gi 1834229548 499 KQGQ 502
Cdd:cd03240   197 KDGR 200
PLN03073 PLN03073
ABC transporter F family; Provisional
 147-503 1.06e-07

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 54.87  E-value: 1.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 147 PEKRLKAlPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVtvqlKILELLKELQARLGMALLLISHDLNLVKRIAH 226
Cdd:PLN03073  335 PEMQVKA-TKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL----HAVLWLETYLLKWPKTFIVVSHAREFLNTVVT 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 227 RVCVMQRGCIV---------EQASCEQLF----------RAPQHPYT----------------RELLAAEPSG------- 264
Cdd:PLN03073  410 DILHLHGQKLVtykgdydtfERTREEQLKnqqkafesneRSRSHMQAfidkfrynakraslvqSRIKALDRLGhvdavvn 489

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 265 ---------TPaTNVVGPPMLTVEDLKVWFPIKKGLLKKtvdyvkavdgINFSLPQGQTLGIVGESGSGKSTlglaILRL 335
Cdd:PLN03073  490 dpdykfefpTP-DDRPGPPIISFSDASFGYPGGPLLFKN----------LNFGIDLDSRIAMVGPNGIGKST----ILKL 554

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 336 IGSkggirfegkqldsltqqqvrplrrEMQVVFQDPFGSLSPRMCV-SQIVGEGLRIHKMGT-------EAEQEQAIIAA 407
Cdd:PLN03073  555 ISG------------------------ELQPSSGTVFRSAKVRMAVfSQHHVDGLDLSSNPLlymmrcfPGVPEQKLRAH 610

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 408 LKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKynltYLFISHDLAV 487
Cdd:PLN03073  611 LGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGLVLFQGG----VLMVSHDEHL 686

                         410
                  ....*....|....*.
gi 1834229548 488 VKALSHQLMVVKQGQV 503
Cdd:PLN03073  687 ISGSVDELWVVSEGKV 702
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
1-248 1.22e-07

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 53.35  E-value: 1.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   1 MNQDNLIEVRDLAVEFVVGERCQRvveGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQnll 80
Cdd:PRK15056    1 MMQQAGIVVNDVTVTWRNGHTALR---DASFTVPGGSIAALVGVNGSGKSTLFKALMGFV-----RLASGKISILGQ--- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  81 nlkeKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIgKVATKRTLEL----LEMVGIPEPEKRLKAlph 156
Cdd:PRK15056   70 ----PTRQALQKNLVAYVPQSEEVDWSFPVLVEDVVMMGRYGHMGWL-RRAKKRDRQIvtaaLARVDMVEFRHRQIG--- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 157 ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVcVMQRGCI 236
Cdd:PRK15056  142 ELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYT-VMVKGTV 219

                         250
                  ....*....|..
gi 1834229548 237 VEQASCEQLFRA 248
Cdd:PRK15056  220 LASGPTETTFTA 231
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 304-498 1.86e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 53.63  E-value: 1.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 304 GIN----FSLP---QGQTLGIVGESGSGKSTLgLAIL--RLI---------GSKGGI--RFEGKQL----DSLTQQQVRP 359
Cdd:COG1245    84 GENgfrlYGLPvpkKGKVTGILGPNGIGKSTA-LKILsgELKpnlgdydeePSWDEVlkRFRGTELqdyfKKLANGEIKV 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 360 LRREMQVvfqdpfgSLSPRMcVSQIVGEGLRihkmgtEAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARAL 439
Cdd:COG1245   163 AHKPQYV-------DLIPKV-FKGTVRELLE------KVDERGKLDELAEKLGLEN-ILDRDISELSGGELQRVAIAAAL 227

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 440 VLKPALILLDEPTSALDrTVQR-QVVELLRSLqSKYNLTYLFISHDLAVVKALSHQLMVV 498
Cdd:COG1245   228 LRDADFYFFDEPSSYLD-IYQRlNVARLIREL-AEEGKYVLVVEHDLAILDYLADYVHIL 285
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 105-495 1.86e-07

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 54.06  E-value: 1.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  105 SLNPLHSIEKQINE-VLGIHKGLIGkvaTKRTLELLEMVGIP--EPEKRLKALphelSGGQRQRVMIAMALANEPE--LL 179
Cdd:PRK00635   428 SLQELFIFLSQLPSkSLSIEEVLQG---LKSRLSILIDLGLPylTPERALATL----SGGEQERTALAKHLGAELIgiTY 500

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  180 IADEPTTALDV--TVQLKILELLKELQarlGMALLLISHDLNLVKrIAHRVCVMQRGCIVEQAscEQLFrapqhpytrel 257
Cdd:PRK00635   501 ILDEPSIGLHPqdTHKLINVIKKLRDQ---GNTVLLVEHDEQMIS-LADRIIDIGPGAGIFGG--EVLF----------- 563

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  258 laaepSGTPATNVVGPPMLTVE----DLKVWFPIKKGLLKKTVDYVKA----VDGINFSLPQGQTLGIVGESGSGKS--- 326
Cdd:PRK00635   564 -----NGSPREFLAKSDSLTAKylrqELTIPIPEKRTNSLGTLTLSKAtkhnLKDLTISLPLGRLTVVTGVSGSGKSsli 638

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  327 --TLGLAILRLI--GSKGGIRFEG--------------------------KQLDSLTQ---QQVRPLRREM---QVVFQD 370
Cdd:PRK00635   639 ndTLVPAVEEFIeqGFCSNLSIQWgaisrlvhitrdlpgrsqrsipltyiKAFDDLRElfaEQPRSKRLGLtksHFSFNT 718

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  371 PFGSLS---------------PRMCVS----QIVGEGLRIHKMGT-----------EAEQ----EQAI---IAALKEVGL 413
Cdd:PRK00635   719 PLGACAecqglgsitttdnrtSIPCPSclgkRFLPQVLEVRYKGKniadilemtayEAEKffldEPSIhekIHALCSLGL 798

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  414 DPETRHRYPHEFSGGQRQRIAIARAL---VLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKA 490
Cdd:PRK00635   799 DYLPLGRPLSSLSGGEIQRLKLAYELlapSKKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGH-TVVIIEHNMHVVKV 877


                   ....*
gi 1834229548  491 LSHQL 495
Cdd:PRK00635   878 ADYVL 882
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
25-249 2.02e-07

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 53.56  E-value: 2.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpyplARH---PSGTIEYSGQNLLNLKektIRHIRGnRIAMIFQE 101
Cdd:PRK10789  330 ALENVNFTLKPGQMLGICGPTGSGKS----TLLSLI----QRHfdvSEGDIRFHDIPLTKLQ---LDSWRS-RLAVVSQT 397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 PMtslnpLHSIEKQINEVLGIHKgligkvATKRTLEllEMVGIPEPEKRLKALPH-----------ELSGGQRQRVMIAM 170
Cdd:PRK10789  398 PF-----LFSDTVANNIALGRPD------ATQQEIE--HVARLASVHDDILRLPQgydtevgergvMLSGGQKQRISIAR 464

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 171 ALANEPELLIADEPTTALDvtVQLKILELLKELQARLGMALLLISHDLNLVKRiAHRVCVMQRGCIVEQASCEQLFRAP 249
Cdd:PRK10789  465 ALLLNAEILILDDALSAVD--GRTEHQILHNLRQWGEGRTVIISAHRLSALTE-ASEILVMQHGHIAQRGNHDQLAQQS 540
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 424-498 2.08e-07

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 51.03  E-value: 2.08e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 424 EFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVVKALSHQLMVV 498
Cdd:cd03222    71 DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVF 145
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 7-216 2.27e-07

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 50.62  E-value: 2.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVefvVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL----PYplarhpsgtieYSGqnllnl 82
Cdd:cd03223     1 IELENLSL---ATPDGRVLLKDLSFEIKPGDRLLITGPSGTGKS----SLFRALaglwPW-----------GSG------ 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 kekTIRHIRGNRIAMIFQEPMTslnPLHSIEKQInevlgihkgligkvatkrtlellemvgipepekrlkALP--HELSG 160
Cdd:cd03223    57 ---RIGMPEGEDLLFLPQRPYL---PLGTLREQL------------------------------------IYPwdDVLSG 94

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 161 GQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKelqaRLGMALLLISH 216
Cdd:cd03223    95 GEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLK----ELGITVISVGH 146
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 159-503 2.57e-07

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 53.25  E-value: 2.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQArlgmALLLISHDLNLVKRIAHRVCVMQRGCIVE 238
Cdd:PRK10636  151 SGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQG----TLILISHDRDFLDPIVDKIIHIEQQSLFE 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 239 --------------------------QASCEQL------FRA----PQHPYTR-------ELLAAEPSGTP------ATN 269
Cdd:PRK10636  227 ytgnyssfevqratrlaqqqamyesqQERVAHLqsyidrFRAkatkAKQAQSRikmlermELIAPAHVDNPfhfsfrAPE 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 270 VVGPPMLTVEDlkvwfpIKKGLLKKTVdyvkaVDGINFSLPQGQTLGIVGESGSGKSTLglaILRLIGS----KGGIRF- 344
Cdd:PRK10636  307 SLPNPLLKMEK------VSAGYGDRII-----LDSIKLNLVPGSRIGLLGRNGAGKSTL---IKLLAGElapvSGEIGLa 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 345 EGKQLDSLTQQQVRPLRREmqvvfQDPFGSLSprmcvsqivgeglRIhkmgTEAEQEQAIIAALKEVGLDPETRHRYPHE 424
Cdd:PRK10636  373 KGIKLGYFAQHQLEFLRAD-----ESPLQHLA-------------RL----APQELEQKLRDYLGGFGFQGDKVTEETRR 430

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 425 FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSkynlTYLFISHDLAVVKALSHQLMVVKQGQV 503
Cdd:PRK10636  431 FSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEG----ALVVVSHDRHLLRSTTDDLYLVHDGKV 505
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 286-470 2.76e-07

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 53.57  E-value: 2.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  286 PIKKG---LLKKTVDYVKAvdginfslpqGQTLGIVGESGSGKSTLgLAIL--RLIGS--KGGIRF-EGKQLDS------ 351
Cdd:TIGR00956  770 KIKKEkrvILNNVDGWVKP----------GTLTALMGASGAGKTTL-LNVLaeRVTTGviTGGDRLvNGRPLDSsfqrsi 838

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  352 -LTQQQ--------VRP-------LRREMQVvfqdpfgSLSPRMcvsQIVGEGLRIHKMGTEAEqeqAIIAALKEvGLDP 415
Cdd:TIGR00956  839 gYVQQQdlhlptstVREslrfsayLRQPKSV-------SKSEKM---EYVEEVIKLLEMESYAD---AVVGVPGE-GLNV 904

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548  416 EtrhryphefsggQRQRIAIARALVLKPALIL-LDEPTSALDRTVQRQVVELLRSL 470
Cdd:TIGR00956  905 E------------QRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL 948
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 32-190 3.84e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 52.86  E-value: 3.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  32 DIKRGETLALVGESGSGKSvTAHSIL--RLLPYPLARHPSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEPMtslnpl 109
Cdd:COG1245   362 EIREGEVLGIVGPNGIGKT-TFAKILagVLKPDEGEVDEDLKISYKPQYISPDYDGTVEEFLRSANTDDFGSSY------ 434

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 110 hsIEKQINEVLGIHKgligkvatkrtleLLEmvgipepeKRLKalphELSGGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:COG1245   435 --YKTEIIKPLGLEK-------------LLD--------KNVK----DLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 487


                  .
gi 1834229548 190 V 190
Cdd:COG1245   488 V 488
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 34-231 5.32e-07

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 51.21  E-value: 5.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  34 KRGETLALVGESGSGKSvTAHSILrllpyplarhpsgtieySGQNLLNLKEKT--------IRHIRGNRIAMIFqepmts 105
Cdd:cd03236    24 REGQVLGLVGPNGIGKS-TALKIL-----------------AGKLKPNLGKFDdppdwdeiLDEFRGSELQNYF------ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 lnplhsiEKQIN-EVLGIHK----GLIGKVATKRTLELL----------EMVGIPEPEKRLKALPHELSGGQRQRVMIAM 170
Cdd:cd03236    80 -------TKLLEgDVKVIVKpqyvDLIPKAVKGKVGELLkkkdergkldELVDQLELRHVLDRNIDQLSGGELQRVAIAA 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 171 ALANEPELLIADEPTTALDVTvQLKILELLKELQARLGMALLLISHDLNLVKRIAHRVCVM 231
Cdd:cd03236   153 ALARDADFYFFDEPSSYLDIK-QRLNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCL 212
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
8-245 6.02e-07

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 52.22  E-value: 6.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   8 EVRdLAVEFVVGercQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLpYPLARHPSGTIEYSGQNLlnlkekti 87
Cdd:PRK11288  255 EVR-LRLDGLKG---PGLREPISFSVRAGEIVGLFGLVGAGRS----ELMKLL-YGATRRTAGQVYLDGKPI-------- 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  88 rHIRGNRIA-----MIFQEPMTSLN--PLHSIEKQIN---EVLGIHKGLI--GKVATKRTLELLEMVGIPEPEKRLKALp 155
Cdd:PRK11288  318 -DIRSPRDAiragiMLCPEDRKAEGiiPVHSVADNINisaRRHHLRAGCLinNRWEAENADRFIRSLNIKTPSREQLIM- 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 156 hELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGC 235
Cdd:PRK11288  396 -NLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVLGVADRIVVMREGR 473

                         250
                  ....*....|....*
gi 1834229548 236 IV-----EQASCEQL 245
Cdd:PRK11288  474 IAgelarEQATERQA 488
PLN03232 PLN03232
ABC transporter C family member; Provisional
 305-536 1.28e-06

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 51.52  E-value: 1.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIgskggirfegkqldsltqqqvrPLRREMQVVFQdpfGSLSPRMCVSQI 384
Cdd:PLN03232   636 INLEIPVGSLVAIVGGTGEGKTSLISAMLGEL----------------------SHAETSSVVIR---GSVAYVPQVSWI 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  385 VGEGLRIHKM-GTEAEQE---QAIIAALKEVGLDPETRHRYPH------EFSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:PLN03232   691 FNATVRENILfGSDFESErywRAIDVTALQHDLDLLPGRDLTEigergvNISGGQKQRVSMARAVYSNSDIYIFDDPLSA 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  455 LDRTVQRQVVE--LLRSLQSKynlTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAAPQhpYTQQLLEAAFLVP 532
Cdd:PLN03232   771 LDAHVAHQVFDscMKDELKGK---TRVLVTNQLHFL-PLMDRIILVSEGMIKEEGTFAELSKSGS--LFKKLMENAGKMD 844


                   ....
gi 1834229548  533 ATAQ 536
Cdd:PLN03232   845 ATQE 848
PLN03211 PLN03211
ABC transporter G-25; Provisional
 25-191 1.65e-06

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 51.03  E-value: 1.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpyplarhpSGTIE---YSGQNLLNLKEKTIRHIRgnRIAMIFQE 101
Cdd:PLN03211   83 ILNGVTGMASPGEILAVLGPSGSGKSTLLNAL------------AGRIQgnnFTGTILANNRKPTKQILK--RTGFVTQD 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 102 PMtsLNPLHSIEKQI--NEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRL--KALPHELSGGQRQRVMIAMALANEPE 177
Cdd:PLN03211  149 DI--LYPHLTVRETLvfCSLLRLPKSLTKQEKILVAESVISELGLTKCENTIigNSFIRGISGGERKRVSIAHEMLINPS 226

                         170
                  ....*....|....
gi 1834229548 178 LLIADEPTTALDVT 191
Cdd:PLN03211  227 LLILDEPTSGLDAT 240
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 305-507 1.68e-06

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 49.18  E-value: 1.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLGLailRLIGSKGGIRFegkqLDSLTQQqVRPLRREMQVVFQDPFGSLSPRMCVSQ- 383
Cdd:cd03270    14 VDVDIPRNKLVVITGVSGSGKSSLAF---DTIYAEGQRRY----VESLSAY-ARQFLGQMDKPDVDSIEGLSPAIAIDQk 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 384 --------IVGEGLRIH--------KMGTEAEqeqaiIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARAL--VLKPAL 445
Cdd:cd03270    86 ttsrnprsTVGTVTEIYdylrllfaRVGIRER-----LGFLVDVGLGYLTLSRSAPTLSGGEAQRIRLATQIgsGLTGVL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 446 ILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKALSHQLMV-----VKQGQVVEQG 507
Cdd:cd03270   161 YVLDEPSIGLHPRDNDRLIETLKRLRDLGN-TVLVVEHDEDTIRAADHVIDIgpgagVHGGEIVAQG 226
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 301-484 1.93e-06

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 50.36  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 301 AVDGINFSLPQGQTLGIVGESGSGKSTlgLAILrLIG----SKGGIRFEGKQLDSLTQQQVRPLrreMQVVFQD------ 370
Cdd:PRK10522  338 SVGPINLTIKRGELLFLIGGNGSGKST--LAML-LTGlyqpQSGEILLDGKPVTAEQPEDYRKL---FSAVFTDfhlfdq 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 371 ---PFGSLSPrmcvSQIVGEGLRIHKMGTEAEQEQAIIAALKevgldpetrhrypheFSGGQRQRIAIARALVLKPALIL 447
Cdd:PRK10522  412 llgPEGKPAN----PALVEKWLERLKMAHKLELEDGRISNLK---------------LSKGQKKRLALLLALAEERDILL 472

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1834229548 448 LDEptSALDRTVQ-RQVV--ELLRSLQSKyNLTYLFISHD 484
Cdd:PRK10522  473 LDE--WAADQDPHfRREFyqVLLPLLQEM-GKTIFAISHD 509
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 7-254 2.17e-06

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 49.14  E-value: 2.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFvvGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKT 86
Cdd:cd03288    20 IKIHDLCVRY--ENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIF-----DGKIVIDGIDISKLPLHT 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRhirgNRIAMIFQEPMtslnpLHSIEKQINevLGIHKgligKVATKRTLELLEmvgIPEPEKRLKALPHEL-------- 158
Cdd:cd03288    93 LR----SRLSIILQDPI-----LFSGSIRFN--LDPEC----KCTDDRLWEALE---IAQLKNMVKSLPGGLdavvtegg 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 159 ---SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQArlGMALLLISHDLNLVKRiAHRVCVMQRGC 235
Cdd:cd03288   155 enfSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFA--DRTVVTIAHRVSTILD-ADLVLVLSRGI 231

                         250
                  ....*....|....*....
gi 1834229548 236 IVEQASCEQLFRAPQHPYT 254
Cdd:cd03288   232 LVECDTPENLLAQEDGVFA 250
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 25-223 2.21e-06

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 50.80  E-value: 2.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPLARH------------------------------------- 67
Cdd:PTZ00265  1183 IYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKNDHHivfknehtndmtneqdyqgdeeqnvgmknvnefsltk 1262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   68 ------PSGTIEYSGQNLL---NLKEKTIRHIRgNRIAMIFQEPMTslnplhsIEKQINEVLGIHKGLIGKVATKRTLEL 138
Cdd:PTZ00265  1263 eggsgeDSTVFKNSGKILLdgvDICDYNLKDLR-NLFSIVSQEPML-------FNMSIYENIKFGKEDATREDVKRACKF 1334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  139 LEMvgipepEKRLKALPHE-----------LSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARL 207
Cdd:PTZ00265  1335 AAI------DEFIESLPNKydtnvgpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKA 1408

                          250
                   ....*....|....*.
gi 1834229548  208 GMALLLISHDLNLVKR 223
Cdd:PTZ00265  1409 DKTIITIAHRIASIKR 1424
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-248 2.45e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 50.17  E-value: 2.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEF-VVGERcqRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIL-RllPYplARHPSGTIeysgqnLLN 81
Cdd:NF040905  255 EVVFEVKNWTVYHpLHPER--KVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFgR--SY--GRNISGTV------FKD 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  82 LKEKTIRHIR---GNRIA----------MIFQEPM---TSLNPLHSIEKQ--INEVLGIhkgligKVATK-------RTL 136
Cdd:NF040905  323 GKEVDVSTVSdaiDAGLAyvtedrkgygLNLIDDIkrnITLANLGKVSRRgvIDENEEI------KVAEEyrkkmniKTP 396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 137 ELLEMVGipepekrlkalphELSGGQRQRVMIAMALANEPELLIADEPTTALDV-------TVqlkilellKELQARLGM 209
Cdd:NF040905  397 SVFQKVG-------------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVgakyeiyTI--------INELAAEGK 455

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1834229548 210 ALLLISHDLNLVKRIAHRVCVMQRGCIV-----EQASCEQLFRA 248
Cdd:NF040905  456 GVIVISSELPELLGMCDRIYVMNEGRITgelprEEASQERIMRL 499
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 32-190 2.96e-06

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 48.56  E-value: 2.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  32 DIKRGETLALVGESGSGKSvtahSILRLLpyplarhpSGTIEYSGQNLLnlkektirhIRGNRIAMIFQE-----PMTSL 106
Cdd:cd03237    21 SISESEVIGILGPNGIGKT----TFIKML--------AGVLKPDEGDIE---------IELDTVSYKPQYikadyEGTVR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 107 NPLHSIEKQinevLGIHKGLIGKVATKrtlelLEMVGIPEPEKRlkalphELSGGQRQRVMIAMALANEPELLIADEPTT 186
Cdd:cd03237    80 DLLSSITKD----FYTHPYFKTEIAKP-----LQIEQILDREVP------ELSGGELQRVAIAACLSKDADIYLLDEPSA 144


                  ....
gi 1834229548 187 ALDV 190
Cdd:cd03237   145 YLDV 148
hmuV PRK13547
heme ABC transporter ATP-binding protein;
158-251 3.46e-06

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 48.67  E-value: 3.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 158 LSGGQRQRVMIAMALAN---------EPELLIADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVKRIAHRV 228
Cdd:PRK13547  146 LSGGELARVQFARVLAQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRI 225

                          90       100
                  ....*....|....*....|...
gi 1834229548 229 CVMQRGCIVEQASCEQLFRaPQH 251
Cdd:PRK13547  226 AMLADGAIVAHGAPADVLT-PAH 247
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 7-248 4.26e-06

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 49.94  E-value: 4.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548    7 IEVRDLAVEFvvGERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLKEKT 86
Cdd:TIGR00957 1285 VEFRNYCLRY--REDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRIN-----ESAEGEIIIDGLNIAKIGLHD 1357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   87 IRhirgNRIAMIFQEPM-------TSLNPLHSIEKQinevlgihkgligKVATKRTLELLEMVGIPEPEKrlkaLPHE-- 157
Cdd:TIGR00957 1358 LR----FKITIIPQDPVlfsgslrMNLDPFSQYSDE-------------EVWWALELAHLKTFVSALPDK----LDHEca 1416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  158 -----LSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQlkilellKELQARL-----GMALLLISHDLNLVKRIAhR 227
Cdd:TIGR00957 1417 eggenLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETD-------NLIQSTIrtqfeDCTVLTIAHRLNTIMDYT-R 1488

                          250       260
                   ....*....|....*....|.
gi 1834229548  228 VCVMQRGCIVEQASCEQLFRA 248
Cdd:TIGR00957 1489 VIVLDKGEVAEFGAPSNLLQQ 1509
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 275-508 7.51e-06

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 47.48  E-value: 7.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 275 MLTVEDLKVwfpikkgllkkTVDYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAilrLIGSK------GGIRFEGKQ 348
Cdd:PRK09580    1 MLSIKDLHV-----------SVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSAT---LAGREdyevtgGTVEFKGKD 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 349 LDSLTqqqvrPLRREMQVVF---QDP--FGSLSPRMCVSQIVGEgLRIHKMGTEAEQ---EQAIIAALKEVGLDPETRHR 420
Cdd:PRK09580   67 LLELS-----PEDRAGEGIFmafQYPveIPGVSNQFFLQTALNA-VRSYRGQEPLDRfdfQDLMEEKIALLKMPEDLLTR 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 421 YPHE-FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLM-VV 498
Cdd:PRK09580  141 SVNVgFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDG-KRSFIIVTHYQRILDYIKPDYVhVL 219

                         250
                  ....*....|
gi 1834229548 499 KQGQVVEQGD 508
Cdd:PRK09580  220 YQGRIVKSGD 229
oligo_HPY pfam08352
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...
 504-527 7.69e-06

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.


Pssm-ID: 400588 [Multi-domain]  Cd Length: 65  Bit Score: 43.54  E-value: 7.69e-06
                          10        20
                  ....*....|....*....|....
gi 1834229548 504 VEQGDAQSIFAAPQHPYTQQLLEA 527
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNS 24
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 306-514 7.77e-06

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 48.47  E-value: 7.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 306 NFSLPQGQTLGIVGESGSGKSTLGLAIL-RLIGSKG--------GIRFEGKQLDSLTQQQVRPLRREMQVVFQDPFGSLs 376
Cdd:PRK10938   23 SLTLNAGDSWAFVGANGSGKSALARALAgELPLLSGerqsqfshITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRT- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 377 prmcVSQIVGEGlriHKMGTEAEQ--EQAIIAALkevgLDpeTRHRYpheFSGGQRQRIAIARALVLKPALILLDEPTSA 454
Cdd:PRK10938  102 ----TAEIIQDE---VKDPARCEQlaQQFGITAL----LD--RRFKY---LSTGETRKTLLCQALMSEPDLLILDEPFDG 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 455 LDRTVQRQVVELLRSLQSKyNLTYLFISHDLAVVKALSHQLMVVKQGQVVEQGDAQSIFA 514
Cdd:PRK10938  166 LDVASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQ 224
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 426-500 1.05e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 45.81  E-value: 1.05e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548 426 SGGQRQRIAIARALVL---KPA-LILLDEPTSALDRTVQRQVVELLRSlQSKYNLTYLFISHDLAVVKALSHQLMVVKQ 500
Cdd:cd03227    79 SGGEKELSALALILALaslKPRpLYILDEIDRGLDPRDGQALAEAILE-HLVKGAQVIVITHLPELAELADKLIHIKKV 156
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 4-225 1.54e-05

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 47.62  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   4 DNLIEVRDLAVEFvvGERCqrVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLL-----PYplarhpSGTIEYSgqn 78
Cdd:TIGR03719 320 DKVIEAENLTKAF--GDKL--LIDDLSFKLPPGGIVGVIGPNGAGKS----TLFRMItgqeqPD------SGTIEIG--- 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  79 llnlkeKTIRhirgnrIAMIFQEpMTSLNPLHSIEKQINEVLGIHKglIGK--VATKRTLELLEMVGiPEPEKRLKalph 156
Cdd:TIGR03719 383 ------ETVK------LAYVDQS-RDALDPNKTVWEEISGGLDIIK--LGKreIPSRAYVGRFNFKG-SDQQKKVG---- 442

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 157 ELSGGQRQRVMIAMALANEPELLIADEPTTALDV-TVQlkilellKELQARLGMA--LLLISHDLNLVKRIA 225
Cdd:TIGR03719 443 QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVeTLR-------ALEEALLNFAgcAVVISHDRWFLDRIA 507
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 23-222 1.54e-05

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 46.10  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPyPLARHPSGTIEYSGQNllnlkektirhIRGNRIA----MI 98
Cdd:PRK13540   14 QPLLQQISFHLPAGGLLHLKGSNGAGKT----TLLKLIA-GLLNPEKGEILFERQS-----------IKKDLCTyqkqLC 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  99 FQEPMTSLNPLHSIEKqiNEVLGIHkgligkvATKRTLELLEMVGIPEPEKRLKALPHELSGGQRQRVMIAMALANEPEL 178
Cdd:PRK13540   78 FVGHRSGINPYLTLRE--NCLYDIH-------FSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKL 148

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1834229548 179 LIADEPTTALDVTVQLKILELLKELQARlGMALLLISH-DLNLVK 222
Cdd:PRK13540  149 WLLDEPLVALDELSLLTIITKIQEHRAK-GGAVLLTSHqDLPLNK 192
PTZ00243 PTZ00243
ABC transporter; Provisional
 305-516 1.87e-05

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 47.85  E-value: 1.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  305 INFSLPQGQTLGIVGESGSGKSTLGLAILRLIGSKGGIRFEGKQLDSLTQQ------QVRPlrremQVVFQDP--FGSLS 376
Cdd:PTZ00243   679 VSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAERSIAYVPQQawimnaTVRG-----NILFFDEedAARLA 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  377 PRMCVSQIVGEgLRIHKMGTEAEqeqaiiaaLKEVGLDpetrhrypheFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PTZ00243   754 DAVRVSQLEAD-LAQLGGGLETE--------IGEKGVN----------LSGGQKARVSLARAVYANRDVYLLDDPLSALD 814

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834229548  457 RTVQRQVVE--LLRSLQSKynlTYLFISHDLAVVkALSHQLMVVKQGQVVEQGDAQSIFAAP 516
Cdd:PTZ00243   815 AHVGERVVEecFLGALAGK---TRVLATHQVHVV-PRADYVVALGDGRVEFSGSSADFMRTS 872
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 292-456 1.90e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 47.42  E-value: 1.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 292 LKKTVDYVKAV-DGINFSLPQGQTLGIVGESGSGKSTLglaiLRLIGskgGI--RFEGKqldsltqqqVRP--------L 360
Cdd:PRK11819   12 VSKVVPPKKQIlKDISLSFFPGAKIGVLGLNGAGKSTL----LRIMA---GVdkEFEGE---------ARPapgikvgyL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 361 RREMQvvfqdpfgsLSPRMCVSQIVGEGLR-----------IH-KMGTE--------AEQE--QAIIAALKevGLDPETR 418
Cdd:PRK11819   76 PQEPQ---------LDPEKTVRENVEEGVAevkaaldrfneIYaAYAEPdadfdalaAEQGelQEIIDAAD--AWDLDSQ 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 419 -------HRYPH------EFSGGQRQRIAIARALVLKPALILLDEPTSALD 456
Cdd:PRK11819  145 leiamdaLRCPPwdakvtKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 23-244 1.94e-05

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 47.03  E-value: 1.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  23 QRVVEGVSFDIKRGETLALVGESGSGKSVTAHSIlrllpYPLARHPSGTIEYSGQNLLNLK-EKTIRH-----IRGNRIA 96
Cdd:PRK10982  261 QPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETL-----FGIREKSAGTITLHGKKINNHNaNEAINHgfalvTEERRST 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  97 MIFQEPMTSLNPLHSIEKQinevlgiHKGLIGKVATKR----TLELLEMVGIPEPEKrlKALPHELSGGQRQRVMIAMAL 172
Cdd:PRK10982  336 GIYAYLDIGFNSLISNIRN-------YKNKVGLLDNSRmksdTQWVIDSMRVKTPGH--RTQIGSLSGGNQQKVIIGRWL 406

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834229548 173 ANEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVCVMQRG---CIVEQASCEQ 244
Cdd:PRK10982  407 LTQPEILMLDEPTRGIDVGAKFEIYQLIAEL-AKKDKGIIIISSEMPELLGITDRILVMSNGlvaGIVDTKTTTQ 480
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
24-246 2.46e-05

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 45.64  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  24 RVVEGVSFDIKRGETLALVGESGSGKSvTAHSILRLLPyplaRHPSGTIEYSGQNLLNLKekTIRHIR--------GNRI 95
Cdd:PRK11614   19 QALHEVSLHINQGEIVTLIGANGAGKT-TLLGTLCGDP----RATSGRIVFDGKDITDWQ--TAKIMReavaivpeGRRV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  96 --AMIFQEPMtSLNPLHSIEKQINEVLgihkgligkvatKRTLELLemvgiPEPEKRLKALPHELSGGQRQRVMIAMALA 173
Cdd:PRK11614   92 fsRMTVEENL-AMGGFFAERDQFQERI------------KWVYELF-----PRLHERRIQRAGTMSGGEQQMLAIGRALM 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 174 NEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIAHRVCVMQRGCIVEQASCEQLF 246
Cdd:PRK11614  154 SQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALL 225
oligo_HPY pfam08352
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...
 237-266 3.26e-05

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.


Pssm-ID: 400588 [Multi-domain]  Cd Length: 65  Bit Score: 42.00  E-value: 3.26e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 1834229548 237 VEQASCEQLFRAPQHPYTRELLAAEPSGTP 266
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDP 30
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 25-193 4.31e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 46.44  E-value: 4.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   25 VVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLArhPS-GTIEYSGqnllnlkektirhirgnRIAMifqEPM 103
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKS----SLLMMIMGELE--PSeGKIKHSG-----------------RISF---SPQ 494

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  104 TSLNPLHSIEKQIneVLGIHKGLIGKVATKRTLELLEMVGIpEPEKRLKALPH---ELSGGQRQRVMIAMALANEPELLI 180
Cdd:TIGR01271  495 TSWIMPGTIKDNI--IFGLSYDEYRYTSVIKACQLEEDIAL-FPEKDKTVLGEggiTLSGGQRARISLARAVYKDADLYL 571

                          170
                   ....*....|...
gi 1834229548  181 ADEPTTALDVTVQ 193
Cdd:TIGR01271  572 LDSPFTHLDVVTE 584
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 426-507 4.87e-05

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 46.16  E-value: 4.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 426 SGGQRQRIAIARALVLK---PALILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKALSHQLMV----- 497
Cdd:TIGR00630 831 SGGEAQRIKLAKELSKRstgRTLYILDEPTTGLHFDDIKKLLEVLQRLVDKGN-TVVVIEHNLDVIKTADYIIDLgpegg 909

                          90
                  ....*....|
gi 1834229548 498 VKQGQVVEQG 507
Cdd:TIGR00630 910 DGGGTVVASG 919
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 2-222 5.49e-05

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 45.90  E-value: 5.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   2 NQDNLIEVRDLAVefvVGERCQRVVEGVSFDIKRGETLALVGESGSGKSvtahSILRLLP--YPLarhpsgtieYSGqnL 79
Cdd:TIGR00954 447 YQDNGIKFENIPL---VTPNGDVLIESLSFEVPSGNNLLICGPNGCGKS----SLFRILGelWPV---------YGG--R 508

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  80 LNLKEKtirhirgNRIAMIFQEPMTSLNPLH-------SIEKQINevlgihKGLIGKVaTKRTLELLEMVGIPEPEKRLK 152
Cdd:TIGR00954 509 LTKPAK-------GKLFYVPQRPYMTLGTLRdqiiypdSSEDMKR------RGLSDKD-LEQILDNVQLTHILEREGGWS 574

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 153 ALPH---ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKelqaRLGMALLLISHDLNLVK 222
Cdd:TIGR00954 575 AVQDwmdVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGYMYRLCR----EFGITLFSVSHRKSLWK 643
oligo_HPY TIGR01727
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...
 236-263 7.41e-05

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 213647 [Multi-domain]  Cd Length: 87  Bit Score: 41.58  E-value: 7.41e-05
                          10        20
                  ....*....|....*....|....*...
gi 1834229548 236 IVEQASCEQLFRAPQHPYTRELLAAEPS 263
Cdd:TIGR01727   2 IVETGPAEEIFKNPLHPYTKALLSAIPT 29
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 305-370 8.21e-05

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 45.17  E-value: 8.21e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834229548 305 INFSLPQGQTLGIVGESGSGKSTLglaiLRLI-G----SKGGIRFEGKQLDSLTQQQVRPLrreMQVVFQD 370
Cdd:COG4615   351 IDLTIRRGELVFIVGGNGSGKSTL----AKLLtGlyrpESGEILLDGQPVTADNREAYRQL---FSAVFSD 414
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 426-504 9.33e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 45.27  E-value: 9.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 426 SGGQRQRIAIARALVLKPALILLDEPTSALDrtvqrqvVELLRSLQS---KYNLTYLFISHDLAVVKALSHQLMVVKQGQ 502
Cdd:PRK15064  440 SGGEKGRMLFGKLMMQKPNVLVMDEPTNHMD-------MESIESLNMaleKYEGTLIFVSHDREFVSSLATRIIEITPDG 512


                  ..
gi 1834229548 503 VV 504
Cdd:PRK15064  513 VV 514
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 35-225 1.07e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 42.75  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   35 RGETLALVGESGSGKSVTAHSILRLLPYPLArhpsGTIEYSGQNLLNLKEKTIRHIRGNRIamifqepmtslnplhsiek 114
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGG----GVIYIDGEDILEEVLDQLLLIIVGGK------------------- 57

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  115 qinevlgihkgligkvatkrtlellemvgipepekrlkalPHELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQ- 193
Cdd:smart00382  58 ----------------------------------------KASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEa 97

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1834229548  194 ----LKILELLKELQARLGMALLLISHDLNLVKRIA 225
Cdd:smart00382  98 llllLEELRLLLLLKSEKNLTVILTTNDEKDLGPAL 133
oligo_HPY TIGR01727
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...
 502-527 1.16e-04

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 213647 [Multi-domain]  Cd Length: 87  Bit Score: 40.81  E-value: 1.16e-04
                          10        20
                  ....*....|....*....|....*.
gi 1834229548 502 QVVEQGDAQSIFAAPQHPYTQQLLEA 527
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSA 26
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 150-338 1.33e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 44.82  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  150 RLKALP-----HELSGGQRQRVMIAMALAN---EPELLIADEPTTALDvTVQLKILELLKELQARLGMALLLISHDLNLV 221
Cdd:PRK00635   797 GLDYLPlgrplSSLSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLH-THDIKALIYVLQSLTHQGHTVVIIEHNMHVV 875

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  222 KrIAHRVCVM------QRGCIVEQASCEQLFrapqHPYTRELLAAEP--SGTPATnvvgpPMLTVEDLKVwfPIKKGLLK 293
Cdd:PRK00635   876 K-VADYVLELgpeggnLGGYLLASCSPEELI----HLHTPTAKALRPylSSPQEL-----PYLPDPSPKP--PVPADITI 943

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1834229548  294 KTVdYVKAVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIGS 338
Cdd:PRK00635   944 KNA-YQHNLKHIDLSLPRNALTAVTGPSASGKHSLVFDILYAAGN 987
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 10-189 1.40e-04

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 44.71  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   10 RDLAVEFVVGERCQRVVEGVSFDIKRGETLALVGESGSGKS--------------VTAHSIL---RLLPYPLARhpsgTI 72
Cdd:TIGR00956  763 RNLTYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTtllnvlaervttgvITGGDRLvngRPLDSSFQR----SI 838

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   73 EYSGQNLLNLKEKTIRHirgnriAMIFQEPMTSLNPLHSIEKQ--INEVLgihkgligkvatkrtlELLEMVGIPEPekr 150
Cdd:TIGR00956  839 GYVQQQDLHLPTSTVRE------SLRFSAYLRQPKSVSKSEKMeyVEEVI----------------KLLEMESYADA--- 893

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1834229548  151 LKALPHE-LSGGQRQRVMIAMALANEPELLI-ADEPTTALD 189
Cdd:TIGR00956  894 VVGVPGEgLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLD 934
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 7-193 1.43e-04

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 43.69  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   7 IEVRDLAVEFVvgERCQRVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplarHPSGTIEYSGQNLLNLKEKT 86
Cdd:cd03289     3 MTVKDLTAKYT--EGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLL------NTEGDIQIDGVSWNSVPLQK 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  87 IRHIRG--NRIAMIFQEPM-TSLNPL--HSIEK--QINEVLGIhKGLIGKVATKRTLELLEMVGIpepekrlkalpheLS 159
Cdd:cd03289    75 WRKAFGviPQKVFIFSGTFrKNLDPYgkWSDEEiwKVAEEVGL-KSVIEQFPGQLDFVLVDGGCV-------------LS 140

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1834229548 160 GGQRQRVMIAMALANEPELLIADEPTTALD-VTVQ 193
Cdd:cd03289   141 HGHKQLMCLARSVLSKAKILLLDEPSAHLDpITYQ 175
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 425-501 1.50e-04

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 45.00  E-value: 1.50e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548  425 FSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLRSLQSKYNLTYLfISHDLAVVKALSHQLMVVKQG 501
Cdd:TIGR01257 2071 YSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVL-TSHSMEECEALCTRLAIMVKG 2146
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 20-234 1.55e-04

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 44.62  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   20 ERCQR-VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPyplarHPSGTIEYSGQNLlnlkEKTIRHIRGNriami 98
Cdd:TIGR01257  939 EPSGRpAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLP-----PTSGTVLVGGKDI----ETNLDAVRQS----- 1004

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   99 fqepmTSLNPLHSI---EKQINEVLGIHKGLIGKVATKRTLELLEMVGIPEPEKRLKALPHELSGGQRQRVMIAMALANE 175
Cdd:TIGR01257 1005 -----LGMCPQHNIlfhHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGD 1079

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834229548  176 PELLIADEPTTALDVTVQlkILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:TIGR01257 1080 AKVVVLDEPTSGVDPYSR--RSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQG 1136
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
153-189 1.56e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 44.73  E-value: 1.56e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1834229548 153 ALPHELSGGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:NF033858  393 ALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 125-232 1.78e-04

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 42.56  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 125 GLIGKVATKRTLELLEMVGIPEPEKRLKALPH----------ELSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQL 194
Cdd:cd03222    29 GIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGitpvykpqyiDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRL 108

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1834229548 195 KILELLKELQARLGMALLLISHDLNLVKRIAHRVCVMQ 232
Cdd:cd03222   109 NAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFE 146
PLN03232 PLN03232
ABC transporter C family member; Provisional
 25-263 2.06e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 44.20  E-value: 2.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKTIRHIrgnrIAMIFQEPMT 104
Cdd:PLN03232  1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELE-----KGRIMIDDCDVAKFGLTDLRRV----LSIIPQSPVL 1321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  105 -------SLNPLhSIEKQINEVLGIHKGLIGKVATKRTLELlemvgipepEKRLKALPHELSGGQRQRVMIAMALANEPE 177
Cdd:PLN03232  1322 fsgtvrfNIDPF-SEHNDADLWEALERAHIKDVIDRNPFGL---------DAEVSEGGENFSVGQRQLLSLARALLRRSK 1391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  178 LLIADEPTTALDVTVQLKILELLKELQARLGMalLLISHDLNLVKRiAHRVCVMQRGCIVEQASCEQLFRAPQHPYTREL 257
Cdd:PLN03232  1392 ILVLDEATASVDVRTDSLIQRTIREEFKSCTM--LVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRDTSAFFRMV 1468


                   ....*.
gi 1834229548  258 LAAEPS 263
Cdd:PLN03232  1469 HSTGPA 1474
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 7-193 2.23e-04

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 44.13  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548    7 IEVRDLAVEFVVGERCqrVVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplarHPSGTIEYSGQNLLNLKEKT 86
Cdd:TIGR01271 1218 MDVQGLTAKYTEAGRA--VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLL------STEGEIQIDGVSWNSVTLQT 1289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   87 IRHIRGNRIAMIFQEPMT---SLNPLHSIEKQ----INEVLGIhKGLIGKVATKRTLELLEMVGIpepekrlkalpheLS 159
Cdd:TIGR01271 1290 WRKAFGVIPQKVFIFSGTfrkNLDPYEQWSDEeiwkVAEEVGL-KSVIEQFPDKLDFVLVDGGYV-------------LS 1355

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1834229548  160 GGQRQRVMIAMALANEPELLIADEPTTALD-VTVQ 193
Cdd:TIGR01271 1356 NGHKQLMCLARSILSKAKILLLDEPSAHLDpVTLQ 1390
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 28-189 2.51e-04

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 42.25  E-value: 2.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  28 GVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLARH--PSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEPMTs 105
Cdd:cd03233    25 DFSGVVKPGEMVLVLGRPGSGCS----TLLKALANRTEGNvsVEGDIHYNGIPYKEFAEKYPGEIIYVSEEDVHFPTLT- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 106 lnplhsiekqinevlgihkgligkvaTKRTLELlemvgipepekRLKALPHE----LSGGQRQRVMIAMALANEPELLIA 181
Cdd:cd03233   100 --------------------------VRETLDF-----------ALRCKGNEfvrgISGGERKRVSIAEALVSRASVLCW 142


                  ....*...
gi 1834229548 182 DEPTTALD 189
Cdd:cd03233   143 DNSTRGLD 150
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 5-189 3.03e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 43.46  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   5 NLIEVRDLAVEFvvGERcqRVVEGVSFDIKRGETLALVGESGSGKSVtahsilrLLPYPLARHPSGtieYSgqNLLNL-- 82
Cdd:PRK10938  259 PRIVLNNGVVSY--NDR--PILHNLSWQVNPGEHWQIVGPNGAGKST-------LLSLITGDHPQG---YS--NDLTLfg 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  83 ----KEKTI----RHIrGNRIAMIFQEPMTSLNPLHSIEKQINEVLGIHKGLIGKvATKRTLELLEMVGIPepeKRLKAL 154
Cdd:PRK10938  323 rrrgSGETIwdikKHI-GYVSSSLHLDYRVSTSVRNVILSGFFDSIGIYQAVSDR-QQKLAQQWLDILGID---KRTADA 397

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1834229548 155 P-HELSGGQRQRVMIAMALANEPELLIADEPTTALD 189
Cdd:PRK10938  398 PfHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLD 433
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 21-230 3.44e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 41.82  E-value: 3.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  21 RCQRVVEGVSFDikRGETLaLVGESGSGKSvtahSILRLLPYPLARH--PSGTIEYSGQNLLNLKEK------TIRHIRG 92
Cdd:cd03240    10 RSFHERSEIEFF--SPLTL-IVGQNGAGKT----TIIEALKYALTGElpPNSKGGAHDPKLIREGEVraqvklAFENANG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  93 NRIAMIfqepmTSLNplhsiekQINEVLGIHKGLIGKVatkrtleLLEMVGipepekrlkalphELSGGQRQ------RV 166
Cdd:cd03240    83 KKYTIT-----RSLA-------ILENVIFCHQGESNWP-------LLDMRG-------------RCSGGEKVlasliiRL 130

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548 167 MIAMALANEPELLIADEPTTALD---VTVQLKILELLKELQArlGMALLLISHDLNLVKRIAHRVCV 230
Cdd:cd03240   131 ALAETFGSNCGILALDEPTTNLDeenIEESLAEIIEERKSQK--NFQLIVITHDEELVDAADHIYRV 195
PLN03232 PLN03232
ABC transporter C family member; Provisional
 158-248 3.49e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 43.43  E-value: 3.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  158 LSGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELQARlGMALLLISHDLNLVKRIaHRVCVMQRGCIV 237
Cdd:PLN03232   741 ISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDSCMKDELK-GKTRVLVTNQLHFLPLM-DRIILVSEGMIK 818

                           90
                   ....*....|.
gi 1834229548  238 EQASCEQLFRA 248
Cdd:PLN03232   819 EEGTFAELSKS 829
ATP-synt_ab pfam00006
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP ...
 299-340 4.20e-04

ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.


Pssm-ID: 425417 [Multi-domain]  Cd Length: 212  Bit Score: 41.96  E-value: 4.20e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1834229548 299 VKAVDGInFSLPQGQTLGIVGESGSGKSTLGLAILR----------LIGSKG 340
Cdd:pfam00006   2 IRAIDGL-LPIGRGQRIGIFGGSGVGKTVLAGMIARqasadvvvyaLIGERG 52
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 159-234 4.73e-04

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 43.08  E-value: 4.73e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548  159 SGGQRQRVMIAMALANEPELLIADEPTTALDVTVQLKILELLKELqARLGMALLLISHDLNLVKRIAHRVCVMQRG 234
Cdd:TIGR01257 2072 SGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSI-IREGRAVVLTSHSMEECEALCTRLAIMVKG 2146
PLN03140 PLN03140
ABC transporter G family member; Provisional
 426-463 5.95e-04

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 42.91  E-value: 5.95e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1834229548  426 SGGQRQRIAIARALVLKPALILLDEPTSALD--------RTVQRQV 463
Cdd:PLN03140  1021 STEQRKRLTIAVELVANPSIIFMDEPTSGLDaraaaivmRTVRNTV 1066
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 29-190 9.31e-04

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 40.78  E-value: 9.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSVTAHSILRLLpyplaRHPSGTIEYSGQNLLNLKEKTIRHIRGNRIAMIFQEPMTsLNP 108
Cdd:cd03290    20 INIRIPTGQLTMIVGQVGCGKSSLLLAILGEM-----QTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWL-LNA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 109 lhSIEKQIneVLGI------HKGLIGKVATKRTLELLEMVGIPEPEKRlkalPHELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:cd03290    94 --TVEENI--TFGSpfnkqrYKAVTDACSLQPDIDLLPFGDQTEIGER----GINLSGGQRQRICVARALYQNTNIVFLD 165


                  ....*...
gi 1834229548 183 EPTTALDV 190
Cdd:cd03290   166 DPFSALDI 173
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
299-472 9.60e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 42.03  E-value: 9.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 299 VKAVDGINFSLPQGQTLGIVGESGSGKSTLglaiLRLI-GSK----GGIR-FEGKQLDSLTQQQVRPlrremQVVFQdPF 372
Cdd:NF033858   14 TVALDDVSLDIPAGCMVGLIGPDGVGKSSL----LSLIaGARkiqqGRVEvLGGDMADARHRRAVCP-----RIAYM-PQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 373 G-------SLSprmcvsqiVGEGLRIHkmGT-----EAEQEQAIIAALKEVGLDPeTRHRYPHEFSGGQRQRIAIARALV 440
Cdd:NF033858   84 GlgknlypTLS--------VFENLDFF--GRlfgqdAAERRRRIDELLRATGLAP-FADRPAGKLSGGMKQKLGLCCALI 152

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1834229548 441 LKPALILLDEPTSALDRTVQRQVVELLRSLQS 472
Cdd:NF033858  153 HDPDLLILDEPTTGVDPLSRRQFWELIDRIRA 184
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 128-190 1.36e-03

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 41.42  E-value: 1.36e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834229548 128 GKVATKRTLELLEMVGIPEPEKrlKALPHELSGGQRQRVMIAMALANEPELLIADEPTTALDV 190
Cdd:PRK15064  128 GYTAEARAGELLLGVGIPEEQH--YGLMSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDI 188
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
422-499 1.39e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 422 PHEFSGGQRQ------RIAIARALVLK-------PALILlDEPTSALDRTVQRQVVELLRSLQSKYNLTYLFISHDLAVV 488
Cdd:PRK02224  779 PEQLSGGERAlfnlslRCAIYRLLAEGiegdaplPPLIL-DEPTVFLDSGHVSQLVDLVESMRRLGVEQIVVVSHDDELV 857

                          90
                  ....*....|.
gi 1834229548 489 KALSHQLMVVK 499
Cdd:PRK02224  858 GAADDLVRVEK 868
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
317-485 1.60e-03

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 39.99  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 317 IVGESGSGKSTLGLAILRLIGSKGGIRfegkqlDSLTQQQVRPLRREMQVVF-----------------QDPFGSLSPRM 379
Cdd:COG0419    28 IVGPNGAGKSTILEAIRYALYGKARSR------SKLRSDLINVGSEEASVELefehggkryrierrqgeFAEFLEAKPSE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 380 cVSQIVGEGLRIHKMG-------------TEAEQEQAIIAALKEVGLDPETRHRYPHEFSGGQRQRIAIARALVLkpali 446
Cdd:COG0419   102 -RKEALKRLLGLEIYEelkerlkeleealESALEELAELQKLKQEILAQLSGLDPIETLSGGERLRLALADLLSL----- 175

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1834229548 447 LLDepTSALDRTVQRQVVELLRSLQskynltylFISHDL 485
Cdd:COG0419   176 ILD--FGSLDEERLERLLDALEELA--------IITHVI 204
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 399-484 1.68e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 41.15  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548 399 EQEQAIIA-ALKE----------VGLDPETRHRYPHEFSGGQRQRIAIARAL--VLKPALILLDEPTSALDRTVQRQVVE 465
Cdd:TIGR00630 452 PEEKKIAEeVLKEirerlgflidVGLDYLSLSRAAGTLSGGEAQRIRLATQIgsGLTGVLYVLDEPSIGLHQRDNRRLIN 531

                          90
                  ....*....|....*....
gi 1834229548 466 LLRSLQSKYNlTYLFISHD 484
Cdd:TIGR00630 532 TLKRLRDLGN-TLIVVEHD 549
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 28-294 1.94e-03

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 41.08  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   28 GVSFDIKRGETLALVGESGSGKSvtahSILRLLPYPLAR-----HPSGTIEYSGQNLLnLKEKTIRHirgnriAMIFQEP 102
Cdd:TIGR00957  656 GITFSIPEGALVAVVGQVGCGKS----SLLSALLAEMDKveghvHMKGSVAYVPQQAW-IQNDSLRE------NILFGKA 724

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  103 mtsLNPLHsiekqinevlgiHKGLIGKVATKRTLELLEmvGIPEPEKRLKALphELSGGQRQRVMIAMALANEPELLIAD 182
Cdd:TIGR00957  725 ---LNEKY------------YQQVLEACALLPDLEILP--SGDRTEIGEKGV--NLSGGQKQRVSLARAVYSNADIYLFD 785

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  183 EPTTALDVTVQLKILELLKELQARL-GMALLLISHDLNLVKRIaHRVCVMQRGCIVEQASCEQLFRAP--------QHPY 253
Cdd:TIGR00957  786 DPLSAVDAHVGKHIFEHVIGPEGVLkNKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDgafaeflrTYAP 864

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1834229548  254 TRELLAAEPSGTPATNVVGPPMLTVED-LKVWFPIKKGLLKK 294
Cdd:TIGR00957  865 DEQQGHLEDSWTALVSGEGKEAKLIENgMLVTDVVGKQLQRQ 906
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 426-526 2.23e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 40.97  E-value: 2.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  426 SGGQRQRIAIARALVL---KPALILLDEPTSALDRTVQRQVVELLRSLQSKYNlTYLFISHDLAVVKalsHQLMVVKQGQ 502
Cdd:PRK00635  1701 SLSEKIAIKIAKFLYLppkHPTLFLLDEIATSLDNQQKSALLVQLRTLVSLGH-SVIYIDHDPALLK---QADYLIEMGP 1776

                           90       100
                   ....*....|....*....|....*
gi 1834229548  503 VVEQGDAQSIFAA-PQHPYTQQLLE 526
Cdd:PRK00635  1777 GSGKTGGKILFSGpPKDISASKDSL 1801
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 408-484 2.68e-03

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 40.26  E-value: 2.68e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834229548 408 LKEVGLdPETRHRYP-HEFSGGQRQRIAIARALVLKPALILLDEPTSALDRTVQRQVVELLrslqSKYNLTYLFISHD 484
Cdd:PRK15064  139 LLGVGI-PEEQHYGLmSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDVL----NERNSTMIIISHD 211
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 157-190 2.76e-03

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 40.49  E-value: 2.76e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1834229548 157 ELSGGQRQRVMIAMALANEPELLIADEPTTALDV 190
Cdd:PRK11819  445 VLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDV 478
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 29-183 6.13e-03

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 39.18  E-value: 6.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  29 VSFDIKRGETLALVGESGSGKSVTAhsilRLLPyPLARHPSGTIEYSGQNLlnlKEKTIRHIRgNRIAMIFQEpmtslnp 108
Cdd:PRK10522  342 INLTIKRGELLFLIGGNGSGKSTLA----MLLT-GLYQPQSGEILLDGKPV---TAEQPEDYR-KLFSAVFTD------- 405

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834229548 109 LHSIEKqineVLGIHKGLIGKVATKRTLELLEMVG-IPEPEKRLKALphELSGGQRQRVMIAMALANEPELLIADE 183
Cdd:PRK10522  406 FHLFDQ----LLGPEGKPANPALVEKWLERLKMAHkLELEDGRISNL--KLSKGQKKRLALLLALAEERDILLLDE 475
PLN03130 PLN03130
ABC transporter C family member; Provisional
 25-245 6.67e-03

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 39.34  E-value: 6.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548   25 VVEGVSFDIKRGETLALVGESGSGKSVTAHSILRLLPYPlarhpSGTIEYSGQNLLNLKEKTIRhirgNRIAMIFQEPMT 104
Cdd:PLN03130  1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELE-----RGRILIDGCDISKFGLMDLR----KVLGIIPQAPVL 1324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834229548  105 -------SLNPLhsiekqiNEvlgiHKgligkvaTKRTLELLEMVGIPEPEKR----LKALPHE----LSGGQRQRVMIA 169
Cdd:PLN03130  1325 fsgtvrfNLDPF-------NE----HN-------DADLWESLERAHLKDVIRRnslgLDAEVSEagenFSVGQRQLLSLA 1386

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834229548  170 MALANEPELLIADEPTTALDVTVQLKILELLKELQARLGMalLLISHDLNLVkrI-AHRVCVMQRGCIVEQASCEQL 245
Cdd:PLN03130  1387 RALLRRSKILVLDEATAAVDVRTDALIQKTIREEFKSCTM--LIIAHRLNTI--IdCDRILVLDAGRVVEFDTPENL 1459
PLN03130 PLN03130
ABC transporter C family member; Provisional
 158-192 6.84e-03

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 39.34  E-value: 6.84e-03
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 1834229548  158 LSGGQRQRVMIAMALANEPELLIADEPTTALDVTV 192
Cdd:PLN03130   741 ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHV 775
AAA_29 pfam13555
P-loop containing region of AAA domain;
310-344 9.24e-03

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 34.88  E-value: 9.24e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1834229548 310 PQGQTLgIVGESGSGKSTLGLAILRLIGSKGGIRF 344
Cdd:pfam13555  21 PRGNTL-LTGPSGSGKSTLLDAIQTLLVPAKRARF 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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