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Conserved domains on  [gi|1828237759|ref|WP_167514701|]
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MurR/RpiR family transcriptional regulator [Mesorhizobium intechi]

Protein Classification

MurR/RpiR family transcriptional regulator( domain architecture ID 11448252)

MurR/RpiR family transcriptional regulator similar to Escherichia coli MurR, which represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid

CATH:  1.10.10.10
Gene Ontology:  GO:0006355|GO:0003700|GO:0003677
PubMed:  15808743|8576032
SCOP:  4000148

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RpiR COG1737
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ...
 8-281 1.20e-68

DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];


:

Pssm-ID: 441343 [Multi-domain]  Cd Length: 286  Bit Score: 214.41  E-value: 1.20e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759   8 DFETLRATILDRRESLPKRIAQIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLRERN 87
Cdd:COG1737     3 SAMSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  88 SSYdERLQALRAKAEGGAghraIFDGFVAAASTSLNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALG 167
Cdd:COG1737    83 SSY-ERLRRLSPDDSLED----ILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 168 KLNIRNQLIESAAGLNAEMIAFATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFARVWFEVAEA- 246
Cdd:COG1737   158 RLGKNVVLLDGDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITDSPLSPLAKLADVVLYVPSEe 237

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1828237759 247 ---DFAGFRSLSATMALAMAMTVGVGEKRRDIGRKRKA 281
Cdd:COG1737   238 ptlRSSAFSSRVAQLALIDALAAAVAQRDGDKARERLE 275
 
Name Accession Description Interval E-value
RpiR COG1737
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ...
 8-281 1.20e-68

DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];


Pssm-ID: 441343 [Multi-domain]  Cd Length: 286  Bit Score: 214.41  E-value: 1.20e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759   8 DFETLRATILDRRESLPKRIAQIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLRERN 87
Cdd:COG1737     3 SAMSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  88 SSYdERLQALRAKAEGGAghraIFDGFVAAASTSLNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALG 167
Cdd:COG1737    83 SSY-ERLRRLSPDDSLED----ILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 168 KLNIRNQLIESAAGLNAEMIAFATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFARVWFEVAEA- 246
Cdd:COG1737   158 RLGKNVVLLDGDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITDSPLSPLAKLADVVLYVPSEe 237

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1828237759 247 ---DFAGFRSLSATMALAMAMTVGVGEKRRDIGRKRKA 281
Cdd:COG1737   238 ptlRSSAFSSRVAQLALIDALAAAVAQRDGDKARERLE 275
SIS_RpiR cd05013
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ...
 134-263 4.02e-27

RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.


Pssm-ID: 240144 [Multi-domain]  Cd Length: 139  Bit Score: 102.31  E-value: 4.02e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 134 LEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKLNIRNQLIESAAGLnAEMIAFATPADAVIAISFSPYAPATIEEAR 213
Cdd:cd05013     3 LEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQ-LMSAANLTPGDVVIAISFSGETKETVEAAE 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1828237759 214 TISEHGVPIVAITDSSFSPLAQFARVWFEVAEADF----AGFRSLSATMALAMA 263
Cdd:cd05013    82 IAKERGAKVIAITDSANSPLAKLADIVLLVSSEEGdfrsSAFSSRIAQLALIDA 135
SIS pfam01380
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ...
 140-266 4.26e-21

SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway.


Pssm-ID: 426230 [Multi-domain]  Cd Length: 131  Bit Score: 86.20  E-value: 4.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 140 LLAKAQTIYVLAKRRSYPVASYIAYALGKLNIRNQLIESAAGLNAEMIAFATPADAVIAISFSPYAPATIEEARTISEHG 219
Cdd:pfam01380   1 LLAKAKRIFVIGRGTSYAIALELALKFEEIGYKVVEVELASELRHGVLALVDEDDLVIAISYSGETKDLLAAAELAKARG 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1828237759 220 VPIVAITDSSFSPLAQFARVWF---EVAEADFAGFRSLSATMALAMAMTV 266
Cdd:pfam01380  81 AKIIAITDSPGSPLAREADHVLyinAGPETGVASTKSITAQLAALDALAV 130
PRK15482 PRK15482
HTH-type transcriptional regulator MurR;
29-237 4.56e-09

HTH-type transcriptional regulator MurR;


Pssm-ID: 185379 [Multi-domain]  Cd Length: 285  Bit Score: 56.25  E-value: 4.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  29 QIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLRERNSSYDERLQALRAKAEGGAGHR 108
Cdd:PRK15482   20 KIADFLRANVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 109 AIFDGFVAAASTSLNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKLNIRnQLIESAAGLNAEMIA 188
Cdd:PRK15482  100 VIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYR-VACEADTHVQATVSQ 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1828237759 189 FATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFA 237
Cdd:PRK15482  179 ALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLA 227
 
Name Accession Description Interval E-value
RpiR COG1737
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ...
 8-281 1.20e-68

DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];


Pssm-ID: 441343 [Multi-domain]  Cd Length: 286  Bit Score: 214.41  E-value: 1.20e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759   8 DFETLRATILDRRESLPKRIAQIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLRERN 87
Cdd:COG1737     3 SAMSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  88 SSYdERLQALRAKAEGGAghraIFDGFVAAASTSLNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALG 167
Cdd:COG1737    83 SSY-ERLRRLSPDDSLED----ILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 168 KLNIRNQLIESAAGLNAEMIAFATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFARVWFEVAEA- 246
Cdd:COG1737   158 RLGKNVVLLDGDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITDSPLSPLAKLADVVLYVPSEe 237

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1828237759 247 ---DFAGFRSLSATMALAMAMTVGVGEKRRDIGRKRKA 281
Cdd:COG1737   238 ptlRSSAFSSRVAQLALIDALAAAVAQRDGDKARERLE 275
SIS_RpiR cd05013
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ...
 134-263 4.02e-27

RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.


Pssm-ID: 240144 [Multi-domain]  Cd Length: 139  Bit Score: 102.31  E-value: 4.02e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 134 LEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKLNIRNQLIESAAGLnAEMIAFATPADAVIAISFSPYAPATIEEAR 213
Cdd:cd05013     3 LEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQ-LMSAANLTPGDVVIAISFSGETKETVEAAE 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1828237759 214 TISEHGVPIVAITDSSFSPLAQFARVWFEVAEADF----AGFRSLSATMALAMA 263
Cdd:cd05013    82 IAKERGAKVIAITDSANSPLAKLADIVLLVSSEEGdfrsSAFSSRIAQLALIDA 135
SIS pfam01380
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ...
 140-266 4.26e-21

SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway.


Pssm-ID: 426230 [Multi-domain]  Cd Length: 131  Bit Score: 86.20  E-value: 4.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 140 LLAKAQTIYVLAKRRSYPVASYIAYALGKLNIRNQLIESAAGLNAEMIAFATPADAVIAISFSPYAPATIEEARTISEHG 219
Cdd:pfam01380   1 LLAKAKRIFVIGRGTSYAIALELALKFEEIGYKVVEVELASELRHGVLALVDEDDLVIAISYSGETKDLLAAAELAKARG 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1828237759 220 VPIVAITDSSFSPLAQFARVWF---EVAEADFAGFRSLSATMALAMAMTV 266
Cdd:pfam01380  81 AKIIAITDSPGSPLAREADHVLyinAGPETGVASTKSITAQLAALDALAV 130
PRK15482 PRK15482
HTH-type transcriptional regulator MurR;
29-237 4.56e-09

HTH-type transcriptional regulator MurR;


Pssm-ID: 185379 [Multi-domain]  Cd Length: 285  Bit Score: 56.25  E-value: 4.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  29 QIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLRERNSSYDERLQALRAKAEGGAGHR 108
Cdd:PRK15482   20 KIADFLRANVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 109 AIFDGFVAAASTSLNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKLNIRnQLIESAAGLNAEMIA 188
Cdd:PRK15482  100 VIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYR-VACEADTHVQATVSQ 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1828237759 189 FATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFA 237
Cdd:PRK15482  179 ALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLA 227
PRK11337 PRK11337
MurR/RpiR family transcriptional regulator;
49-239 5.71e-09

MurR/RpiR family transcriptional regulator;


Pssm-ID: 183089 [Multi-domain]  Cd Length: 292  Bit Score: 55.92  E-value: 5.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  49 IAASAGVQPSTLIRFAQQLGFDGF----TSLQQVFRERLRERNS--SYDERLQALRAKaeggaghraIFDgfvaaasTSL 122
Cdd:PRK11337   52 IAEALAVSEAMIVKVAKKLGFSGFrnlrSALEDYFSQSEQVLHSelSFDDAPQDVVNK---------VFN-------TSL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 123 NDISRT---LDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKLNIRNQ-------LIESAAGLnaemiafaTP 192
Cdd:PRK11337  116 QAIEETqsiLDVDEFHRAARFFYQARQRDLYGAGGSAAIARDVQHKFLRIGVRCQayddahiMLMSAALL--------QE 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1828237759 193 ADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFARV 239
Cdd:PRK11337  188 GDVVLVVSHSGRTSDVIEAVELAKKNGAKIICITNSYHSPIAKLADY 234
PRK14101 PRK14101
bifunctional transcriptional regulator/glucokinase;
9-243 1.04e-08

bifunctional transcriptional regulator/glucokinase;


Pssm-ID: 184507 [Multi-domain]  Cd Length: 638  Bit Score: 55.69  E-value: 1.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759   9 FETLRAtILDRRESLPKRIAQIAayaLDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLRERNS 88
Cdd:PRK14101  344 FERIRQ-MRDALTPAERRVADLA---LNHPRSIINDPIVDIARKADVSQPTVIRFCRSLGCQGLSDFKLKLATGLTGTIP 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  89 SYDERLQALRAKAEGGAghrAIFDGFVAAastsLNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGK 168
Cdd:PRK14101  420 MSHSQVHLGDTATDFGA---KVLDNTVSA----ILQLREHLNFEHVEQAIDILNNARRIEFYGLGNSNIVAQDAHYKFFR 492

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828237759 169 LNIRNqLIESAAGLNAEMIAFATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITdSSFSPLAQFARVWFEV 243
Cdd:PRK14101  493 FGIPT-IAYGDLYMQAASAALLGKGDVIVAVSKSGRAPELLRVLDVAMQAGAKVIAIT-SSNTPLAKRATVALET 565
PRK11557 PRK11557
MurR/RpiR family transcriptional regulator;
16-264 3.59e-07

MurR/RpiR family transcriptional regulator;


Pssm-ID: 183195 [Multi-domain]  Cd Length: 278  Bit Score: 50.15  E-value: 3.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  16 ILDRRESLPKRIAQIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLRERNSSYDERL- 94
Cdd:PRK11557    3 IRQRYPGLAQSDRKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGYKGFPALKLALSEALASQPEPPSVPVh 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  95 -QALRAKAEGGAGHRAIFDGfVAAASTSLnDISrtlDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKLNIrN 173
Cdd:PRK11557   83 nQIRGDDPLRLVGEKLIKEN-TAAMRATL-DVN---SEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGI-N 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 174 QLIESAAGLNAEMIAFATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFA-RVWFEVAEADF---A 249
Cdd:PRK11557  157 AVAERDMHALLATVQALSPDDLLLAISYSGERRELNLAADEALRVGAKVLAITGFTPNALQQRAsHCLYTIAEEQAtrsA 236

                         250
                  ....*....|....*....
gi 1828237759 250 GFRSLSATMALA----MAM 264
Cdd:PRK11557  237 AISSTHAQGMLTdllfMAL 255
HTH_6 pfam01418
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best ...
 16-75 4.13e-07

Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best characterized member of this family is Swiss:P39266. RpiR is a regulator of the expression of rpiB gene.


Pssm-ID: 334531 [Multi-domain]  Cd Length: 77  Bit Score: 46.55  E-value: 4.13e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  16 ILDRRESLPKRIAQIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSL 75
Cdd:pfam01418   7 IQSRYSKLTKSERKIADYILAHPDLAIHLSISAIAKAAGVSEATIVRFCQKLGFSGFPEL 66
SIS cd04795
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ...
 147-227 2.46e-04

SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.


Pssm-ID: 240112 [Multi-domain]  Cd Length: 87  Bit Score: 39.28  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 147 IYVLAKRRSYPVASYIAYALGKLNIRNQLIESAAGL-NAEMIAFATPADAVIAISFSPYAPATIEEARTISEHGVPIVAI 225
Cdd:cd04795     1 IFVIGIGGSGAIAAYFALELLELTGIEVVALIATELeHASLLSLLRKGDVVIALSYSGRTEELLAALEIAKELGIPVIAI 80


                  ..
gi 1828237759 226 TD 227
Cdd:cd04795    81 TD 82
SIS_PHI cd05005
Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) ...
 122-237 7.47e-04

Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with formadelhyde to become hexulose-6-phosphate, which is then isomerized to fructose-6-phosphate by PHI.


Pssm-ID: 240138 [Multi-domain]  Cd Length: 179  Bit Score: 39.48  E-value: 7.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759 122 LNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKLnirnqliesaaGLNA----EMIafaTPA---- 193
Cdd:cd05005    11 IENVADKIDEEELDKLISAILNAKRIFVYGAGRSGLVAKAFAMRLMHL-----------GLNVyvvgETT---TPAigpg 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1828237759 194 DAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFA 237
Cdd:cd05005    77 DLLIAISGSGETSSVVNAAEKAKKAGAKVVLITSNPDSPLAKLA 120
PRK11302 PRK11302
DNA-binding transcriptional regulator HexR; Provisional
 16-237 2.18e-03

DNA-binding transcriptional regulator HexR; Provisional


Pssm-ID: 183082 [Multi-domain]  Cd Length: 284  Bit Score: 38.82  E-value: 2.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  16 ILDRRESLPKRIAQIAAYALDNPDDIAFGTAASIAASAGVQPSTLIRFAQQLGFDGFTSLQQVFRERLR------ERNSS 89
Cdd:PRK11302    7 IQSRLEHLSKSERKVAEVILASPQTAIHSSIATLAKMANVSEPTVNRFCRSLDTKGFPDFKLHLAQSLAngtpyvNRNVE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828237759  90 YDERLQALRAKaeggaghraIFDGFVAaastSLNDISRTLDDAHLEDAISLLAKAQTIYVLAKRRSYPVASYIAYALGKL 169
Cdd:PRK11302   87 EDDSVEAYTGK---------IFESAMA----SLDHARQSLDPSAINRAVDLLTQAKKISFFGLGASAAVAHDAQNKFFRF 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1828237759 170 NIrnQLIESAAGLNAEMIAF-ATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITdSSFSPLAQFA 237
Cdd:PRK11302  154 NV--PVVYFDDIVMQRMSCMnSSDGDVVVLISHTGRTKSLVELAQLARENGATVIAIT-SAGSPLAREA 219
SIS_Kpsf cd05014
KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ...
 191-267 9.91e-03

KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose 5-phosphate to arabinose 5-phosphate. This is the second step in the CMP-Kdo biosynthesis pathway.


Pssm-ID: 240145 [Multi-domain]  Cd Length: 128  Bit Score: 35.60  E-value: 9.91e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1828237759 191 TPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFARVWFEVAEADFAGFRSLSATMALAMAMTVG 267
Cdd:cd05014    46 TPGDVVIAISNSGETDELLNLLPHLKRRGAPIIAITGNPNSTLAKLSDVVLDLPVEEEACPLGLAPTTSTTAMLALG 122
PRK13938 PRK13938
phosphoheptose isomerase; Provisional
 190-247 9.94e-03

phosphoheptose isomerase; Provisional


Pssm-ID: 139997 [Multi-domain]  Cd Length: 196  Bit Score: 36.25  E-value: 9.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1828237759 190 ATPADAVIAISFSPYAPATIEEARTISEHGVPIVAITDSSFSPLAQFARVWFEVAEAD 247
Cdd:PRK13938  111 ARPGDTLFAISTSGNSMSVLRAAKTARELGVTVVAMTGESGGQLAEFADFLINVPSRD 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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