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Concise Results
Standard Results
Full Results
MULTISPECIES: malate synthase A [Proteus]
Protein Classification
malate synthase ( domain architecture ID 10006197 )
malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA, in the glyoxylate cycle
List of domain hits
Name
Accession
Description
Interval
E-value
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
3-530
0e+00
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 1019.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 3 QSL T KEELNF T QSF G KQEK EIL NHDVKL FL TD L LNH F SD RR HT LLA E R DNWKN R V D N GELP N F IS E SD SI INSE WKV N PI 82
Cdd:COG2225 1 TQT T PSGVEI T GPL G PRYE EIL TPEALA FL AE L HRR F AP RR QE LLA A R AERQA R I D A GELP D F LP E TA SI REGD WKV A PI 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 83 P K DLQDRRVEITGPVDRKMVINALN ANV KVFMADFED SLA PTWD K VI D GQINLRDAV K GTIS Y T NEQ GK C Y Q L KAS PA V L 162
Cdd:COG2225 81 P P DLQDRRVEITGPVDRKMVINALN SGA KVFMADFED ANS PTWD N VI E GQINLRDAV R GTIS F T SPE GK E Y R L NDK PA T L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 163 I A R V RG L HLPEKHVL WK GEPI A G G LFDF A LYF Y HN H KALL EK GSGPYFY I PKL QTWQ EA KW W S DVF H F TEKRF G LAT GTI 242
Cdd:COG2225 161 I V R P RG W HLPEKHVL VD GEPI S G S LFDF G LYF F HN A KALL AR GSGPYFY L PKL ESHL EA RL W N DVF V F AQDEL G IPR GTI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 243 KATVLIET L PA V F Q M E EIL FHMKE H IV GLNCGRWDYIFSYIKT LK N Y PD R VLPDR QGI TMT Q PF LS AYS R LL IQ TCH K RG 322
Cdd:COG2225 241 KATVLIET I PA A F E M D EIL YELRD H SA GLNCGRWDYIFSYIKT FR N H PD F VLPDR AQV TMT V PF MR AYS E LL VK TCH R RG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 323 A F A M GGM S AFIP SR - DPE Q N GII L K KV FD DKE L EA TN GHDGTW I AHPGL AETVLSA FDAVLG A R S NQLD VQ R NE - KI TA E 400
Cdd:COG2225 321 A H A I GGM A AFIP IK n DPE A N EAA L A KV RA DKE R EA ND GHDGTW V AHPGL VPVAMEV FDAVLG D R P NQLD RL R ED v SV TA A 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 401 M LL APCT G ER TE K G M R A NI R V AV QY I EAW IS GNG C VPIY G LMEDAATAEISR TSI WQWI R H QK TL S DG QI VT KD L F R NM L 480
Cdd:COG2225 401 D LL DVPE G TI TE A G L R N NI S V GI QY L EAW LR GNG A VPIY N LMEDAATAEISR SQV WQWI H H GA TL D DG RK VT AE L V R QL L 480
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1803202057 481 K EEL EVI R Q EVG DT RFE E GRF K EAA S L MDKITTQ DE LV DFLTLP G Y QL L N 530
Cdd:COG2225 481 A EEL AKL R A EVG EE RFE A GRF D EAA E L FEELVLS DE FP DFLTLP A Y ER L D 530
Name
Accession
Description
Interval
E-value
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
3-530
0e+00
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 1019.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 3 QSL T KEELNF T QSF G KQEK EIL NHDVKL FL TD L LNH F SD RR HT LLA E R DNWKN R V D N GELP N F IS E SD SI INSE WKV N PI 82
Cdd:COG2225 1 TQT T PSGVEI T GPL G PRYE EIL TPEALA FL AE L HRR F AP RR QE LLA A R AERQA R I D A GELP D F LP E TA SI REGD WKV A PI 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 83 P K DLQDRRVEITGPVDRKMVINALN ANV KVFMADFED SLA PTWD K VI D GQINLRDAV K GTIS Y T NEQ GK C Y Q L KAS PA V L 162
Cdd:COG2225 81 P P DLQDRRVEITGPVDRKMVINALN SGA KVFMADFED ANS PTWD N VI E GQINLRDAV R GTIS F T SPE GK E Y R L NDK PA T L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 163 I A R V RG L HLPEKHVL WK GEPI A G G LFDF A LYF Y HN H KALL EK GSGPYFY I PKL QTWQ EA KW W S DVF H F TEKRF G LAT GTI 242
Cdd:COG2225 161 I V R P RG W HLPEKHVL VD GEPI S G S LFDF G LYF F HN A KALL AR GSGPYFY L PKL ESHL EA RL W N DVF V F AQDEL G IPR GTI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 243 KATVLIET L PA V F Q M E EIL FHMKE H IV GLNCGRWDYIFSYIKT LK N Y PD R VLPDR QGI TMT Q PF LS AYS R LL IQ TCH K RG 322
Cdd:COG2225 241 KATVLIET I PA A F E M D EIL YELRD H SA GLNCGRWDYIFSYIKT FR N H PD F VLPDR AQV TMT V PF MR AYS E LL VK TCH R RG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 323 A F A M GGM S AFIP SR - DPE Q N GII L K KV FD DKE L EA TN GHDGTW I AHPGL AETVLSA FDAVLG A R S NQLD VQ R NE - KI TA E 400
Cdd:COG2225 321 A H A I GGM A AFIP IK n DPE A N EAA L A KV RA DKE R EA ND GHDGTW V AHPGL VPVAMEV FDAVLG D R P NQLD RL R ED v SV TA A 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 401 M LL APCT G ER TE K G M R A NI R V AV QY I EAW IS GNG C VPIY G LMEDAATAEISR TSI WQWI R H QK TL S DG QI VT KD L F R NM L 480
Cdd:COG2225 401 D LL DVPE G TI TE A G L R N NI S V GI QY L EAW LR GNG A VPIY N LMEDAATAEISR SQV WQWI H H GA TL D DG RK VT AE L V R QL L 480
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1803202057 481 K EEL EVI R Q EVG DT RFE E GRF K EAA S L MDKITTQ DE LV DFLTLP G Y QL L N 530
Cdd:COG2225 481 A EEL AKL R A EVG EE RFE A GRF D EAA E L FEELVLS DE FP DFLTLP A Y ER L D 530
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
23-530
0e+00
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 851.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 23 IL NHDVKL FL TD L LNH F SD RR HT LLA E R DNWKN R V D N GELP N F IS E SDS I INSE WKV N P I P K DLQDRRVEITGPVDRKMV 102
Cdd:cd00727 1 IL TPEALD FL AE L HRR F NP RR KE LLA A R KERQA R L D A GELP D F LP E TAH I RDGD WKV A P V P P DLQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 103 INALN ANV KVFMADFED SL APTW DKVID GQINLRDAV K GTIS Y T NEQ GK C Y Q L KAS PA V LI A R V RG L HLPEKHVL WK GEP 182
Cdd:cd00727 81 INALN SGA KVFMADFED AN APTW ENQVE GQINLRDAV R GTIS F T SPE GK E Y K L NDT PA T LI V R P RG W HLPEKHVL VD GEP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 183 IA G G LFDF A LYF Y HN H KALL EK GSGPYFY I PK LQTWQ EA KW W S DVF H F TEKRF GL AT GTIKATVLIETLPA V F Q M E EIL F 262
Cdd:cd00727 161 VS G S LFDF G LYF F HN A KALL AR GSGPYFY L PK MESHL EA RL W N DVF V F AQDYL GL PR GTIKATVLIETLPA A F E M D EIL Y 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 263 HMKE H IV GLNCGRWDYIFS Y IK TLK N Y PD R VLPDR QGI TMT Q PF LS AYS R LLI Q TCH K RGA F AMGGM S A F IP SR - DP EQ N 341
Cdd:cd00727 241 ELRD H SA GLNCGRWDYIFS F IK KFR N H PD F VLPDR AQV TMT V PF MR AYS E LLI K TCH R RGA H AMGGM A A Q IP IK d DP AA N 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 342 GII L K KV FD DK EL EAT N GHDGTW I AHPGL AETVLSA FD AVLG a RS NQLDV Q R NE - K I TA EM LL A - P CT G ER TE K G M R A NI 419
Cdd:cd00727 321 EAA L A KV RA DK LR EAT A GHDGTW V AHPGL VPVAMEV FD KHMP - GP NQLDV L R ED v K V TA AD LL L v P VE G GI TE E G L R Q NI 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 420 R V AV QY IE AW IS GNGCVPIY G LMEDAATAEISR TSI WQWIRH QKT - L S DG QI VT KD L FRNM L K EEL EVIRQ EVG DTR F EE 498
Cdd:cd00727 400 S V GL QY LA AW LR GNGCVPIY N LMEDAATAEISR AQL WQWIRH GVR l L D DG RP VT AE L VEKL L A EEL AKLKA EVG QAG F AT 479
490 500 510
....*....|....*....|....*....|..
gi 1803202057 499 GR FK EAA S L MDKIT T QD E LVD FLTLP G Y QL L N 530
Cdd:cd00727 480 GR LA EAA E L FEELV T AE E FPE FLTLP A Y DD L V 511
malate_syn_A
TIGR01344 malate synthase A; This model represents plant malate synthase and one of two bacterial forms, ...
23-529
0e+00
malate synthase A; This model represents plant malate synthase and one of two bacterial forms, designated malate synthase A. The distantly related malate synthase G is described by a separate model. This enzyme and isocitrate lyase are the two characteristic enzymes of the glyoxylate shunt. The shunt enables the cell to use acetyl-CoA to generate increased levels of TCA cycle intermediates for biosynthetic pathways such as gluconeogenesis. [Energy metabolism, TCA cycle]
Pssm-ID: 188132
Cd Length: 511
Bit Score: 796.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 23 I L NHDVKL FL TD L LNH F SD RR HT LLA E R D N WKNRV D N G E LP N F IS E SDS I INSE W KVN PIP K DLQDRRVEITGPVDRKMV 102
Cdd:TIGR01344 1 V L TPEALE FL AL L HRR F NP RR DQ LLA R R S N RQAKI D S G Y LP D F LP E TAQ I REDD W TIA PIP P DLQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 103 INALNA NV KVFMADFEDS LA PTW DK VI D GQINLRDA VK G T I SY T NEQ - GK C Y Q L K A SP AVLI A R V RG L HLPE K H VLWK GE 181
Cdd:TIGR01344 81 INALNA GA KVFMADFEDS SS PTW EN VI Y GQINLRDA IR G Q I DF T DPT s GK E Y A L N A RL AVLI V R P RG W HLPE R H LTID GE 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 182 P I A G G LFDF A LYF Y HN HK ALL E KG S GPYFY I PKL QTW QEA KW W S DVFHF TEKRF GL AT GTIKATVLIETLPA V F Q M E EIL 261
Cdd:TIGR01344 161 A I P G S LFDF G LYF F HN AR ALL K KG K GPYFY L PKL ESH QEA RL W N DVFHF AQDFL GL PR GTIKATVLIETLPA A F E M D EIL 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 262 FHMK EHI V GLNCGRWDYIFS Y IKTL K N Y P DR VLPDR QGI TMT Q PFL S AYS R LLIQTCH K RGA F AMGGM S AFIP SR - DP EQ 340
Cdd:TIGR01344 241 YELR EHI S GLNCGRWDYIFS F IKTL R N L P EF VLPDR DAV TMT K PFL N AYS K LLIQTCH R RGA H AMGGM A AFIP IK g DP AA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 341 N GIILK KV FD DK EL EA T NGHDGTW I AHP G L AETVLSA F DA V L G A r S NQLD VQ R N E -- K ITA EM LLA PCT G E RTE K G M R A N 418
Cdd:TIGR01344 321 N EAAFN KV RA DK IR EA K NGHDGTW V AHP D L VPVAMEV F NN V M G T - P NQLD RV R D E dv S ITA AE LLA VPD G S RTE A G L R H N 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 419 IRV AV QYIEAW IS G N GCVPIY G LMEDAATAEISR TSI WQWI R H QKT L S DG QI VT KD LFR NM L KE E LEVI R Q E V G DTR F EE 498
Cdd:TIGR01344 400 IRV GL QYIEAW LR G S GCVPIY H LMEDAATAEISR AQL WQWI K H GVV L D DG RV VT PE LFR DL L NQ E MGKL R S E S G LEE F AA 479
490 500 510
....*....|....*....|....*....|.
gi 1803202057 499 GRF K EAA S L MDKIT T QD EL V DFLT L P G Y QL L 529
Cdd:TIGR01344 480 GRF E EAA K L FLRLV T SK EL E DFLT I P A Y DE L 510
Malate_synthase
pfam01274 Malate synthase;
12-529
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 727.26
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 12 F TQSFGKQEKE IL NHDVKL F LTD L LNH F SD RR HT LLA E RD NWKN R V D N G E LP N F IS E SDS I INS - E WK VNPIPKD LQDRR 90
Cdd:pfam01274 3 F VGPYVLPGTG IL TKEALS F VAE L HRD F TP RR RE LLA R RD ERQA R I D A G H LP D F LP E TGY I RPD p D WK TATLHPE LQDRR 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 91 VEITGP V DRKM V INALN ANVKVF MADFEDS L APTW DKV I D GQ I NL R DAV K G T I SYTNEQ - GK C Y Q L K --- ASP A V L IA R V 166
Cdd:pfam01274 83 VEITGP A DRKM I INALN SGAITT MADFEDS V APTW NNL I Q GQ L NL Y DAV R G R I DFRDLN a GK S Y K L N dgl HGR A T L FV R P 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 167 RG L HLPEKH V L WK GEPI A GG L FDF A LYF Y HN H K A L LEK G S GPYFY I PK LQTW QEA KW W S DVF HFT E KRF G LAT GTI K ATV 246
Cdd:pfam01274 163 RG W HLPEKH I L VD GEPI P GG I FDF G LYF F HN A K E L NSR G G GPYFY L PK MEHH QEA AL W N DVF NRA E DYL G IPR GTI R ATV 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 247 LIETLPA V FQM E EI LFHMKE H IV GLNCGRWDYIFSYIKTL K N Y PD R VLPDR QGI TMT Q PF LS AY SR LLI Q TCHKRG AF AM 326
Cdd:pfam01274 243 LIETLPA S FQM D EI IYELRD H SA GLNCGRWDYIFSYIKTL R N A PD M VLPDR KAV TMT A PF MR AY EK LLI K TCHKRG VH AM 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 327 GGM S A F IP SR - D P E Q N GIILK KV FD DK EL E ATN GHDGTW I AHPGLA ETVLSA F DA V LG a R S NQ LDVQ R N E - K ITA EM LL A 404
Cdd:pfam01274 323 GGM A A Q IP IK d D M E A N TAAME KV RA DK LR E VRA GHDGTW V AHPGLA PLAAEV F HQ V MV - R P NQ IELA R E E d S ITA DD LL T 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 405 PCT GE R TE K G M R A NI R V AV QY I EAW IS G N GCVPI YG LMEDAATAEISR TSI WQW I RH QK TL SD G QI VT KD L FRNMLK EE L 484
Cdd:pfam01274 402 IPD GE E TE E G L R N NI Q V GL QY V EAW LR G S GCVPI IH LMEDAATAEISR QQL WQW L RH GV TL DE G VR VT LE L MAKLVD EE N 481
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1803202057 485 EVIRQ E vgdt RF EE G RFKE AA S L MDKIT T QD E LV DFLTL PG Y QL L 529
Cdd:pfam01274 482 ARLAK E ---- RF GD G AYRD AA R L FLQQA T AE E YD DFLTL LA Y DD L 522
PLN02626
PLN02626 malate synthase
22-526
0e+00
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 701.53
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 22 E IL NH D VKL F LT DL LNH F SD RR HT LL AE R DNWKN R V D N G E LP N F ISESDSIINSE W KVN P I P KDLQ DRRVEITGPV D RKM 101
Cdd:PLN02626 24 K IL TR D ALQ F VA DL QRE F RP RR KY LL EC R REAQR R Y D A G A LP G F DPATRAVREGD W RCA P V P PAVA DRRVEITGPV E RKM 103
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 102 VINALN ANV KVFMADFEDSL A PTW DKVID GQ I NLRDAV K GTI SY T NEQ - GK C Y Q L KASP A V L IA R V RG L HLPE K H V L WK G 180
Cdd:PLN02626 104 VINALN SGA KVFMADFEDSL S PTW ENLMR GQ V NLRDAV R GTI TF T DKA r GK V Y K L NDKT A K L FV R P RG W HLPE A H I L VD G 183
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 181 EP IA G G LFDF A LYF Y HN HK A LLE K -- G S GP Y FY I PK LQTWQ EA KW W S DVF HFT EK RF G LAT G T I K ATVLIETLPAVFQME 258
Cdd:PLN02626 184 EP AT G S LFDF G LYF F HN YA A FRA K qg G F GP F FY L PK MEHSR EA RL W N DVF EAA EK MA G IPR G S I R ATVLIETLPAVFQME 263
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 259 EIL FHMKE H IV GLNCGRWDYIFS YI KT LKNY PDR V LPDR QGIT MTQ P F LSA Y SR LLI Q TCHKRG AF AMGGM S A F IP SR - D 337
Cdd:PLN02626 264 EIL YELRD H SA GLNCGRWDYIFS FV KT FRAH PDR L LPDR VQVG MTQ H F MKS Y VD LLI K TCHKRG VH AMGGM A A Q IP IK d D 343
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 338 P EQ N GII L KK V FD DK EL E ATN GHDGTW I AHPGL AETVLSA FD AVLGARS NQ LDVQ R NE -- KI T AEM LL APCT G E RT EK G M 415
Cdd:PLN02626 344 P AA N EAA L AL V RK DK LR E VRA GHDGTW A AHPGL IPLAMEV FD GHMPTPN NQ QLHK R RD dv NV T EAD LL QVPR G V RT LE G L 423
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 416 R A N I RV AV QY IE AW IS G N G C VP I Y G LMEDAATAEISR TSI WQWI RHQKT L SDGQI --- VT KD LF RNMLK EE LEV I RQ EVG 492
Cdd:PLN02626 424 R L N T RV GI QY LA AW LT G T G S VP L Y N LMEDAATAEISR VQN WQWI KYGAE L DGDGV gvr VT AE LF GRVVE EE MAR I ER EVG 503
490 500 510
....*....|....*....|....*....|....
gi 1803202057 493 DT RF EE G RF KEAA S L MDKIT T QD EL V DFLTL PG Y 526
Cdd:PLN02626 504 KE RF KK G KY KEAA K L FARQC T AP EL D DFLTL DA Y 537
Name
Accession
Description
Interval
E-value
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
3-530
0e+00
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 1019.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 3 QSL T KEELNF T QSF G KQEK EIL NHDVKL FL TD L LNH F SD RR HT LLA E R DNWKN R V D N GELP N F IS E SD SI INSE WKV N PI 82
Cdd:COG2225 1 TQT T PSGVEI T GPL G PRYE EIL TPEALA FL AE L HRR F AP RR QE LLA A R AERQA R I D A GELP D F LP E TA SI REGD WKV A PI 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 83 P K DLQDRRVEITGPVDRKMVINALN ANV KVFMADFED SLA PTWD K VI D GQINLRDAV K GTIS Y T NEQ GK C Y Q L KAS PA V L 162
Cdd:COG2225 81 P P DLQDRRVEITGPVDRKMVINALN SGA KVFMADFED ANS PTWD N VI E GQINLRDAV R GTIS F T SPE GK E Y R L NDK PA T L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 163 I A R V RG L HLPEKHVL WK GEPI A G G LFDF A LYF Y HN H KALL EK GSGPYFY I PKL QTWQ EA KW W S DVF H F TEKRF G LAT GTI 242
Cdd:COG2225 161 I V R P RG W HLPEKHVL VD GEPI S G S LFDF G LYF F HN A KALL AR GSGPYFY L PKL ESHL EA RL W N DVF V F AQDEL G IPR GTI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 243 KATVLIET L PA V F Q M E EIL FHMKE H IV GLNCGRWDYIFSYIKT LK N Y PD R VLPDR QGI TMT Q PF LS AYS R LL IQ TCH K RG 322
Cdd:COG2225 241 KATVLIET I PA A F E M D EIL YELRD H SA GLNCGRWDYIFSYIKT FR N H PD F VLPDR AQV TMT V PF MR AYS E LL VK TCH R RG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 323 A F A M GGM S AFIP SR - DPE Q N GII L K KV FD DKE L EA TN GHDGTW I AHPGL AETVLSA FDAVLG A R S NQLD VQ R NE - KI TA E 400
Cdd:COG2225 321 A H A I GGM A AFIP IK n DPE A N EAA L A KV RA DKE R EA ND GHDGTW V AHPGL VPVAMEV FDAVLG D R P NQLD RL R ED v SV TA A 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 401 M LL APCT G ER TE K G M R A NI R V AV QY I EAW IS GNG C VPIY G LMEDAATAEISR TSI WQWI R H QK TL S DG QI VT KD L F R NM L 480
Cdd:COG2225 401 D LL DVPE G TI TE A G L R N NI S V GI QY L EAW LR GNG A VPIY N LMEDAATAEISR SQV WQWI H H GA TL D DG RK VT AE L V R QL L 480
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1803202057 481 K EEL EVI R Q EVG DT RFE E GRF K EAA S L MDKITTQ DE LV DFLTLP G Y QL L N 530
Cdd:COG2225 481 A EEL AKL R A EVG EE RFE A GRF D EAA E L FEELVLS DE FP DFLTLP A Y ER L D 530
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
23-530
0e+00
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 851.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 23 IL NHDVKL FL TD L LNH F SD RR HT LLA E R DNWKN R V D N GELP N F IS E SDS I INSE WKV N P I P K DLQDRRVEITGPVDRKMV 102
Cdd:cd00727 1 IL TPEALD FL AE L HRR F NP RR KE LLA A R KERQA R L D A GELP D F LP E TAH I RDGD WKV A P V P P DLQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 103 INALN ANV KVFMADFED SL APTW DKVID GQINLRDAV K GTIS Y T NEQ GK C Y Q L KAS PA V LI A R V RG L HLPEKHVL WK GEP 182
Cdd:cd00727 81 INALN SGA KVFMADFED AN APTW ENQVE GQINLRDAV R GTIS F T SPE GK E Y K L NDT PA T LI V R P RG W HLPEKHVL VD GEP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 183 IA G G LFDF A LYF Y HN H KALL EK GSGPYFY I PK LQTWQ EA KW W S DVF H F TEKRF GL AT GTIKATVLIETLPA V F Q M E EIL F 262
Cdd:cd00727 161 VS G S LFDF G LYF F HN A KALL AR GSGPYFY L PK MESHL EA RL W N DVF V F AQDYL GL PR GTIKATVLIETLPA A F E M D EIL Y 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 263 HMKE H IV GLNCGRWDYIFS Y IK TLK N Y PD R VLPDR QGI TMT Q PF LS AYS R LLI Q TCH K RGA F AMGGM S A F IP SR - DP EQ N 341
Cdd:cd00727 241 ELRD H SA GLNCGRWDYIFS F IK KFR N H PD F VLPDR AQV TMT V PF MR AYS E LLI K TCH R RGA H AMGGM A A Q IP IK d DP AA N 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 342 GII L K KV FD DK EL EAT N GHDGTW I AHPGL AETVLSA FD AVLG a RS NQLDV Q R NE - K I TA EM LL A - P CT G ER TE K G M R A NI 419
Cdd:cd00727 321 EAA L A KV RA DK LR EAT A GHDGTW V AHPGL VPVAMEV FD KHMP - GP NQLDV L R ED v K V TA AD LL L v P VE G GI TE E G L R Q NI 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 420 R V AV QY IE AW IS GNGCVPIY G LMEDAATAEISR TSI WQWIRH QKT - L S DG QI VT KD L FRNM L K EEL EVIRQ EVG DTR F EE 498
Cdd:cd00727 400 S V GL QY LA AW LR GNGCVPIY N LMEDAATAEISR AQL WQWIRH GVR l L D DG RP VT AE L VEKL L A EEL AKLKA EVG QAG F AT 479
490 500 510
....*....|....*....|....*....|..
gi 1803202057 499 GR FK EAA S L MDKIT T QD E LVD FLTLP G Y QL L N 530
Cdd:cd00727 480 GR LA EAA E L FEELV T AE E FPE FLTLP A Y DD L V 511
malate_syn_A
TIGR01344 malate synthase A; This model represents plant malate synthase and one of two bacterial forms, ...
23-529
0e+00
malate synthase A; This model represents plant malate synthase and one of two bacterial forms, designated malate synthase A. The distantly related malate synthase G is described by a separate model. This enzyme and isocitrate lyase are the two characteristic enzymes of the glyoxylate shunt. The shunt enables the cell to use acetyl-CoA to generate increased levels of TCA cycle intermediates for biosynthetic pathways such as gluconeogenesis. [Energy metabolism, TCA cycle]
Pssm-ID: 188132
Cd Length: 511
Bit Score: 796.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 23 I L NHDVKL FL TD L LNH F SD RR HT LLA E R D N WKNRV D N G E LP N F IS E SDS I INSE W KVN PIP K DLQDRRVEITGPVDRKMV 102
Cdd:TIGR01344 1 V L TPEALE FL AL L HRR F NP RR DQ LLA R R S N RQAKI D S G Y LP D F LP E TAQ I REDD W TIA PIP P DLQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 103 INALNA NV KVFMADFEDS LA PTW DK VI D GQINLRDA VK G T I SY T NEQ - GK C Y Q L K A SP AVLI A R V RG L HLPE K H VLWK GE 181
Cdd:TIGR01344 81 INALNA GA KVFMADFEDS SS PTW EN VI Y GQINLRDA IR G Q I DF T DPT s GK E Y A L N A RL AVLI V R P RG W HLPE R H LTID GE 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 182 P I A G G LFDF A LYF Y HN HK ALL E KG S GPYFY I PKL QTW QEA KW W S DVFHF TEKRF GL AT GTIKATVLIETLPA V F Q M E EIL 261
Cdd:TIGR01344 161 A I P G S LFDF G LYF F HN AR ALL K KG K GPYFY L PKL ESH QEA RL W N DVFHF AQDFL GL PR GTIKATVLIETLPA A F E M D EIL 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 262 FHMK EHI V GLNCGRWDYIFS Y IKTL K N Y P DR VLPDR QGI TMT Q PFL S AYS R LLIQTCH K RGA F AMGGM S AFIP SR - DP EQ 340
Cdd:TIGR01344 241 YELR EHI S GLNCGRWDYIFS F IKTL R N L P EF VLPDR DAV TMT K PFL N AYS K LLIQTCH R RGA H AMGGM A AFIP IK g DP AA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 341 N GIILK KV FD DK EL EA T NGHDGTW I AHP G L AETVLSA F DA V L G A r S NQLD VQ R N E -- K ITA EM LLA PCT G E RTE K G M R A N 418
Cdd:TIGR01344 321 N EAAFN KV RA DK IR EA K NGHDGTW V AHP D L VPVAMEV F NN V M G T - P NQLD RV R D E dv S ITA AE LLA VPD G S RTE A G L R H N 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 419 IRV AV QYIEAW IS G N GCVPIY G LMEDAATAEISR TSI WQWI R H QKT L S DG QI VT KD LFR NM L KE E LEVI R Q E V G DTR F EE 498
Cdd:TIGR01344 400 IRV GL QYIEAW LR G S GCVPIY H LMEDAATAEISR AQL WQWI K H GVV L D DG RV VT PE LFR DL L NQ E MGKL R S E S G LEE F AA 479
490 500 510
....*....|....*....|....*....|.
gi 1803202057 499 GRF K EAA S L MDKIT T QD EL V DFLT L P G Y QL L 529
Cdd:TIGR01344 480 GRF E EAA K L FLRLV T SK EL E DFLT I P A Y DE L 510
malate_synt
cd00480 Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , ...
31-530
0e+00
Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238267
Cd Length: 511
Bit Score: 759.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 31 F LTD L LNH F SD RR HT LLA E RD NWKN R V D N G E - LP N F IS E SDS I I - NSE WKV N P I P K DL Q DRRVEITGP V DRKMVINALN A 108
Cdd:cd00480 4 F VAE L HRE F NP RR RE LLA A RD ERQA R L D A G H a LP D F LP E TAY I R r DGD WKV A P D P P DL D DRRVEITGP Q DRKMVINALN S 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 109 NVK VFMADFEDS L APTW DKVID GQ I NL R DAV K GTIS Y T NEQ - GK C Y Q L K -- ASP A V L IA R V RG L HL P EKH V L WK GEP IA G 185
Cdd:cd00480 84 GAA VFMADFEDS S APTW ENKVE GQ R NL L DAV R GTIS F T DSK n GK S Y R L N ll DGR A T L FV R P RG W HL T EKH I L VD GEP VP G 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 186 GLFDF A LYF Y HN HK AL LEK GSGPYFY I PK LQTWQ EA KW W S DVF HFT E KRF GL AT GTIKATVLIETLPA V F Q M E EIL FHMK 265
Cdd:cd00480 164 GLFDF G LYF F HN AH AL KAR GSGPYFY L PK MESPL EA RL W N DVF SRA E DYL GL PR GTIKATVLIETLPA A F E M D EIL YELR 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 266 E H IV GLNCGRWDYIFS Y IKT LK N Y PD R VLPDR QGI TMT Q PF LS AY SR LL IQ TCH K RGA F AMGGM S A F IP SR - DP EQ N GII 344
Cdd:cd00480 244 D H SA GLNCGRWDYIFS E IKT FR N H PD F VLPDR AKV TMT S PF MR AY EK LL VK TCH R RGA H AMGGM A A Q IP IK g DP AA N EAA 323
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 345 LK KV FD DK EL EA TN GHDGTW I AHPGLA ETVLSA F DA V LG a RS NQL DVQ R NE - K I TA EM LL A -- PCT G ER TE K G M R A NI R V 421
Cdd:cd00480 324 MA KV RA DK LR EA KA GHDGTW V AHPGLA PLAALV F HK V MP - GP NQL FRK R ED v K V TA DD LL T ip VAE G DI TE E G L R N NI Q V 402
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 422 A VQ Y IE AW IS GNG C VPI YG LMEDAATAEISR TSI WQW I RH QKT L S DG QI VT KD L FRNMLK EE LEVIRQEVGDTR F EEGR F 501
Cdd:cd00480 403 A LG Y VV AW LN GNG A VPI IN LMEDAATAEISR SQL WQW L RH GVC L D DG VP VT LE L VAKLVD EE NARLPAYRPPNF F DSIA F 482
490 500
....*....|....*....|....*....
gi 1803202057 502 KEAA S L MDKIT T QD E LVD FLT L P G Y Q LL N 530
Cdd:cd00480 483 KEAA D L FFEGV T AE E FPE FLT E P L Y H LL R 511
Malate_synthase
pfam01274 Malate synthase;
12-529
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 727.26
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 12 F TQSFGKQEKE IL NHDVKL F LTD L LNH F SD RR HT LLA E RD NWKN R V D N G E LP N F IS E SDS I INS - E WK VNPIPKD LQDRR 90
Cdd:pfam01274 3 F VGPYVLPGTG IL TKEALS F VAE L HRD F TP RR RE LLA R RD ERQA R I D A G H LP D F LP E TGY I RPD p D WK TATLHPE LQDRR 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 91 VEITGP V DRKM V INALN ANVKVF MADFEDS L APTW DKV I D GQ I NL R DAV K G T I SYTNEQ - GK C Y Q L K --- ASP A V L IA R V 166
Cdd:pfam01274 83 VEITGP A DRKM I INALN SGAITT MADFEDS V APTW NNL I Q GQ L NL Y DAV R G R I DFRDLN a GK S Y K L N dgl HGR A T L FV R P 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 167 RG L HLPEKH V L WK GEPI A GG L FDF A LYF Y HN H K A L LEK G S GPYFY I PK LQTW QEA KW W S DVF HFT E KRF G LAT GTI K ATV 246
Cdd:pfam01274 163 RG W HLPEKH I L VD GEPI P GG I FDF G LYF F HN A K E L NSR G G GPYFY L PK MEHH QEA AL W N DVF NRA E DYL G IPR GTI R ATV 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 247 LIETLPA V FQM E EI LFHMKE H IV GLNCGRWDYIFSYIKTL K N Y PD R VLPDR QGI TMT Q PF LS AY SR LLI Q TCHKRG AF AM 326
Cdd:pfam01274 243 LIETLPA S FQM D EI IYELRD H SA GLNCGRWDYIFSYIKTL R N A PD M VLPDR KAV TMT A PF MR AY EK LLI K TCHKRG VH AM 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 327 GGM S A F IP SR - D P E Q N GIILK KV FD DK EL E ATN GHDGTW I AHPGLA ETVLSA F DA V LG a R S NQ LDVQ R N E - K ITA EM LL A 404
Cdd:pfam01274 323 GGM A A Q IP IK d D M E A N TAAME KV RA DK LR E VRA GHDGTW V AHPGLA PLAAEV F HQ V MV - R P NQ IELA R E E d S ITA DD LL T 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 405 PCT GE R TE K G M R A NI R V AV QY I EAW IS G N GCVPI YG LMEDAATAEISR TSI WQW I RH QK TL SD G QI VT KD L FRNMLK EE L 484
Cdd:pfam01274 402 IPD GE E TE E G L R N NI Q V GL QY V EAW LR G S GCVPI IH LMEDAATAEISR QQL WQW L RH GV TL DE G VR VT LE L MAKLVD EE N 481
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1803202057 485 EVIRQ E vgdt RF EE G RFKE AA S L MDKIT T QD E LV DFLTL PG Y QL L 529
Cdd:pfam01274 482 ARLAK E ---- RF GD G AYRD AA R L FLQQA T AE E YD DFLTL LA Y DD L 522
PLN02626
PLN02626 malate synthase
22-526
0e+00
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 701.53
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 22 E IL NH D VKL F LT DL LNH F SD RR HT LL AE R DNWKN R V D N G E LP N F ISESDSIINSE W KVN P I P KDLQ DRRVEITGPV D RKM 101
Cdd:PLN02626 24 K IL TR D ALQ F VA DL QRE F RP RR KY LL EC R REAQR R Y D A G A LP G F DPATRAVREGD W RCA P V P PAVA DRRVEITGPV E RKM 103
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 102 VINALN ANV KVFMADFEDSL A PTW DKVID GQ I NLRDAV K GTI SY T NEQ - GK C Y Q L KASP A V L IA R V RG L HLPE K H V L WK G 180
Cdd:PLN02626 104 VINALN SGA KVFMADFEDSL S PTW ENLMR GQ V NLRDAV R GTI TF T DKA r GK V Y K L NDKT A K L FV R P RG W HLPE A H I L VD G 183
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 181 EP IA G G LFDF A LYF Y HN HK A LLE K -- G S GP Y FY I PK LQTWQ EA KW W S DVF HFT EK RF G LAT G T I K ATVLIETLPAVFQME 258
Cdd:PLN02626 184 EP AT G S LFDF G LYF F HN YA A FRA K qg G F GP F FY L PK MEHSR EA RL W N DVF EAA EK MA G IPR G S I R ATVLIETLPAVFQME 263
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 259 EIL FHMKE H IV GLNCGRWDYIFS YI KT LKNY PDR V LPDR QGIT MTQ P F LSA Y SR LLI Q TCHKRG AF AMGGM S A F IP SR - D 337
Cdd:PLN02626 264 EIL YELRD H SA GLNCGRWDYIFS FV KT FRAH PDR L LPDR VQVG MTQ H F MKS Y VD LLI K TCHKRG VH AMGGM A A Q IP IK d D 343
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 338 P EQ N GII L KK V FD DK EL E ATN GHDGTW I AHPGL AETVLSA FD AVLGARS NQ LDVQ R NE -- KI T AEM LL APCT G E RT EK G M 415
Cdd:PLN02626 344 P AA N EAA L AL V RK DK LR E VRA GHDGTW A AHPGL IPLAMEV FD GHMPTPN NQ QLHK R RD dv NV T EAD LL QVPR G V RT LE G L 423
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 416 R A N I RV AV QY IE AW IS G N G C VP I Y G LMEDAATAEISR TSI WQWI RHQKT L SDGQI --- VT KD LF RNMLK EE LEV I RQ EVG 492
Cdd:PLN02626 424 R L N T RV GI QY LA AW LT G T G S VP L Y N LMEDAATAEISR VQN WQWI KYGAE L DGDGV gvr VT AE LF GRVVE EE MAR I ER EVG 503
490 500 510
....*....|....*....|....*....|....
gi 1803202057 493 DT RF EE G RF KEAA S L MDKIT T QD EL V DFLTL PG Y 526
Cdd:PLN02626 504 KE RF KK G KY KEAA K L FARQC T AP EL D DFLTL DA Y 537
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
116-493
2.48e-05
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 47.02
E-value: 2.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 116 D F EDS L A PT -- W DKV I d GQI N LRDAV KG TI ------------------- S YT NEQ G KCYQ L KASPAVLIAR V R gl HL PEK 174
Cdd:cd00728 264 D C EDS V A AV da E DKV L - VYR N WLGLM KG DL aeevekngrtftrklnadr N YT TPD G GEIT L PGRSLMFVRN V G -- HL MTN 340
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 175 HVLW -- K G EPIAG G LF D --- FA L YFY H N hkall E KG SGPY ------- F YI -- PK LQTWQ E AKWWSDV F HFT E KRF GL ATG 240
Cdd:cd00728 341 DAIL ds D G NEVPE G IM D avi TS L IAL H D ----- L KG NSAF gnsrtgs I YI vk PK MHGPE E VAFANEL F SRV E DLL GL PQN 415
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 241 TIK ATVLI E TLPAVFQME E ILFHMKEHI V GL N C G RW D YIFSY I K T LKNYPDRV lpd R QGITMTQ P FLS AY SRLLIQT --- 317
Cdd:cd00728 416 TIK MGIMD E ERRTSVNLK E CIRAARDRV V FI N T G FL D RTGDE I H T SMEAGPMA --- R KADMKSS P WIG AY EDNNVDI gla 492
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 318 CHKR G AFAM G - GM S A F ipsrd P EQ ngii LKKVFDD K ELEATN G HDGT W IAH P GL A ET - V L SAFDAVLG A RSNQ L DVQ R NE 395
Cdd:cd00728 493 AGLS G KAQI G k GM W A M ----- P DL ---- MADMMEQ K IAHPKA G ANTA W VPS P TA A TL h A L HYHQVNVF A VQKE L AKR R PA 563
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 396 KIT a EM L LA P C ------ TGERTEKGMRA N IRVAVQ Y IEA W IS - G N GC -- VP - I Y -- GLMED A AT AE IS RTS I WQ W I RH qk 463
Cdd:cd00728 564 DLD - DL L TI P L aenanw SPQEIQSELDN N VQGILG Y VVR W VD q G I GC sk VP d I N nv GLMED R AT LR IS SQH I AN W L RH -- 640
410 420 430
....*....|....*....|....*....|.
gi 1803202057 464 tlsdg Q I V TK DLFRNM L KEELE V I - R Q EV GD 493
Cdd:cd00728 641 ----- G I C TK EQVQES L ERMAK V V d Q Q NA GD 666
PRK02999
PRK02999 malate synthase G; Provisional
425-514
6.07e-03
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 39.38
E-value: 6.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1803202057 425 Y IEA W I - S G N GC -- VP - I Y -- GLMED A AT AE IS RTS I WQ W I RH qktlsdg QI VT KDLFRNM LK EELE V I - R Q EV GD ---- 493
Cdd:PRK02999 607 Y VVR W V d Q G V GC sk VP d I H dv GLMED R AT LR IS SQH I AN W L RH ------- GV VT EEQVMES LK RMAA V V d Q Q NA GD payr 679
90 100
....*....|....*....|....*
gi 1803202057 494 --- TR F EEG - R F KE A AS L MD K ITT Q 514
Cdd:PRK02999 680 pma PD F DNS i A F QA A CD L VF K GRE Q 704
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
