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Conserved domains on  [gi|1789698468|ref|WP_158245464|]
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MULTISPECIES: alpha/beta hydrolase family protein [unclassified Petrotoga]

Protein Classification

alpha/beta hydrolase( domain architecture ID 11427881)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  19508187|12369917|37582413

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FrmB COG0627
S-formylglutathione hydrolase FrmB [Defense mechanisms];
8-272 5.22e-78

S-formylglutathione hydrolase FrmB [Defense mechanisms];


:

Pssm-ID: 440392 [Multi-domain]  Cd Length: 249  Bit Score: 236.65  E-value: 5.22e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468   8 ESLSFYSRALKSDVKYSIYLPPKYDieTRKYPTIYLLHGHGGNETSWLRKGRVDQSLDLmitnneiPPFVAVMPDA-KNS 86
Cdd:COG0627     5 VRVTVPSPALGREMPVSVYLPPGYD--GRPLPVLYLLHGLTGTHENWTRKTGAQRLAAE-------LGVIVVMPDGgQAS 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  87 WYVNSPTGV----NYETALIEDLLQHIETQYKVYNERSSRFIAGLSMGGYGALRLAFKYPELFLSVASLSGGITREVPPE 162
Cdd:COG0627    76 FYVDWTQGPaghyRWETYLTEELPPLIEANFPVSADRERRAIAGLSMGGHGALTLALRHPDLFRAVAAFSGILDPSQPPW 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 163 KevdlygneihvrEDYYHDAFGwPFDPKFWEKENIFNYIEHVKQSgleLPVYLSCGSEDYFYLYlGASELHHELRINGIS 242
Cdd:COG0627   156 G------------EKAFDAYFG-PPDRAAWAANDPLALAEKLRAG---LPLYIDCGTADPFFLE-ANRQLHAALRAAGIP 218

                         250       260       270
                  ....*....|....*....|....*....|
gi 1789698468 243 STLFIKPGDHNWFLWSQEIKDVLRFFAKNM 272
Cdd:COG0627   219 HTYRERPGGHSWYYWASFLEDHLPFLARAL 248
 
Name Accession Description Interval E-value
FrmB COG0627
S-formylglutathione hydrolase FrmB [Defense mechanisms];
8-272 5.22e-78

S-formylglutathione hydrolase FrmB [Defense mechanisms];


Pssm-ID: 440392 [Multi-domain]  Cd Length: 249  Bit Score: 236.65  E-value: 5.22e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468   8 ESLSFYSRALKSDVKYSIYLPPKYDieTRKYPTIYLLHGHGGNETSWLRKGRVDQSLDLmitnneiPPFVAVMPDA-KNS 86
Cdd:COG0627     5 VRVTVPSPALGREMPVSVYLPPGYD--GRPLPVLYLLHGLTGTHENWTRKTGAQRLAAE-------LGVIVVMPDGgQAS 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  87 WYVNSPTGV----NYETALIEDLLQHIETQYKVYNERSSRFIAGLSMGGYGALRLAFKYPELFLSVASLSGGITREVPPE 162
Cdd:COG0627    76 FYVDWTQGPaghyRWETYLTEELPPLIEANFPVSADRERRAIAGLSMGGHGALTLALRHPDLFRAVAAFSGILDPSQPPW 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 163 KevdlygneihvrEDYYHDAFGwPFDPKFWEKENIFNYIEHVKQSgleLPVYLSCGSEDYFYLYlGASELHHELRINGIS 242
Cdd:COG0627   156 G------------EKAFDAYFG-PPDRAAWAANDPLALAEKLRAG---LPLYIDCGTADPFFLE-ANRQLHAALRAAGIP 218

                         250       260       270
                  ....*....|....*....|....*....|
gi 1789698468 243 STLFIKPGDHNWFLWSQEIKDVLRFFAKNM 272
Cdd:COG0627   219 HTYRERPGGHSWYYWASFLEDHLPFLARAL 248
Esterase pfam00756
Putative esterase; This family contains Esterase D. However it is not clear if all members of ...
 14-268 7.00e-27

Putative esterase; This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.


Pssm-ID: 395613 [Multi-domain]  Cd Length: 246  Bit Score: 104.85  E-value: 7.00e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  14 SRALKSDVKYSIYLPPKYDiETRKYPTIYLLHGhggneTSWLRKGRVDQSLDLMITNNEIPPFVAV-MPDA-KNSWYVNS 91
Cdd:pfam00756   1 SNSLGREMKVQVYLPEDYP-PGRKYPVLYLLDG-----TGWFQNGPAKEGLDRLAASGEIPPVIIVgSPRGgEVSFYSDW 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  92 PTGVN---------YETALIEDLLQHIETQYKVYneRSSRFIAGLSMGGYGALRLAFKYPELFLSVASLSGGITREVPPe 162
Cdd:pfam00756  75 DRGLNategpgayaYETFLTQELPPLLDANFPTA--PDGRALAGQSMGGLGALYLALKYPDLFGSVSSFSPILNPSNSM- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 163 kevdlygneihvredyyhdaFGWPFDPKFWE---KENIFNYIEHVKQsgleLPVYLSCGSEDYFYLYL----------GA 229
Cdd:pfam00756 152 --------------------WGPEDDPAWQEgdpVLLAVALSANNTR----LRIYLDVGTREDFLGDQlpveileelaPN 207

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1789698468 230 SELHHELRINGISSTLFIKPGDHNWFLWSQEIKDVLRFF 268
Cdd:pfam00756 208 RELAEQLAYRGVGGYDHEYYGGHDWAYWRAQLIAALIDL 246
esterase_phb TIGR01840
esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ...
 76-154 3.21e-04

esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation]


Pssm-ID: 273828 [Multi-domain]  Cd Length: 212  Bit Score: 40.93  E-value: 3.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  76 FVAVMPDAKNswYVNSPTGVNY-----------ETALIEDLLQHIETQYKVYNERssRFIAGLSMGGYGALRLAFKYPEL 144
Cdd:TIGR01840  44 FVLVAPEQTS--YNSSNNCWDWffthhrargtgEVESLHQLIDAVKANYSIDPNR--VYVTGLSAGGGMTAVLGCTYPDV 119

                          90
                  ....*....|
gi 1789698468 145 FLSVASLSGG 154
Cdd:TIGR01840 120 FAGGASNAGL 129
 
Name Accession Description Interval E-value
FrmB COG0627
S-formylglutathione hydrolase FrmB [Defense mechanisms];
8-272 5.22e-78

S-formylglutathione hydrolase FrmB [Defense mechanisms];


Pssm-ID: 440392 [Multi-domain]  Cd Length: 249  Bit Score: 236.65  E-value: 5.22e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468   8 ESLSFYSRALKSDVKYSIYLPPKYDieTRKYPTIYLLHGHGGNETSWLRKGRVDQSLDLmitnneiPPFVAVMPDA-KNS 86
Cdd:COG0627     5 VRVTVPSPALGREMPVSVYLPPGYD--GRPLPVLYLLHGLTGTHENWTRKTGAQRLAAE-------LGVIVVMPDGgQAS 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  87 WYVNSPTGV----NYETALIEDLLQHIETQYKVYNERSSRFIAGLSMGGYGALRLAFKYPELFLSVASLSGGITREVPPE 162
Cdd:COG0627    76 FYVDWTQGPaghyRWETYLTEELPPLIEANFPVSADRERRAIAGLSMGGHGALTLALRHPDLFRAVAAFSGILDPSQPPW 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 163 KevdlygneihvrEDYYHDAFGwPFDPKFWEKENIFNYIEHVKQSgleLPVYLSCGSEDYFYLYlGASELHHELRINGIS 242
Cdd:COG0627   156 G------------EKAFDAYFG-PPDRAAWAANDPLALAEKLRAG---LPLYIDCGTADPFFLE-ANRQLHAALRAAGIP 218

                         250       260       270
                  ....*....|....*....|....*....|
gi 1789698468 243 STLFIKPGDHNWFLWSQEIKDVLRFFAKNM 272
Cdd:COG0627   219 HTYRERPGGHSWYYWASFLEDHLPFLARAL 248
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
3-271 5.88e-67

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 210.86  E-value: 5.88e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468   3 HGKVyESLSFYSRALKSDVKYSIYLPPKYDIETRKYPTIYLLHGHGGNETSWLRKGRVDQSLDLMITNNEIPPFVAVMPD 82
Cdd:COG2382    78 HGTV-ETVTYPSKALGRTRRVWVYLPPGYDNPGKKYPVLYLLDGGGGDEQDWFDQGRLPTILDNLIAAGKIPPMIVVMPD 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  83 AKNS--WYVNSPTGVNYETALIEDLLQHIETQYKVYNERSSRFIAGLSMGGYGALRLAFKYPELFLSVASLSGgitrevp 160
Cdd:COG2382   157 GGDGgdRGTEGPGNDAFERFLAEELIPFVEKNYRVSADPEHRAIAGLSMGGLAALYAALRHPDLFGYVGSFSG------- 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 161 pekevdlygneihvredyyhdAFGWPFDPkfwekENIFNYIEHVKQSGLE--LPVYLSCGSEDYFylYLGASELHHELRI 238
Cdd:COG2382   230 ---------------------SFWWPPGD-----ADRGGWAELLAAGAPKkpLRFYLDVGTEDDL--LEANRALAAALKA 281

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1789698468 239 NGISSTLFIKPGDHNWFLWSQEIKDVLRFFAKN 271
Cdd:COG2382   282 KGYDVEYREFPGGHDWAVWRAALPDFLPWLFKD 314
Esterase pfam00756
Putative esterase; This family contains Esterase D. However it is not clear if all members of ...
 14-268 7.00e-27

Putative esterase; This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.


Pssm-ID: 395613 [Multi-domain]  Cd Length: 246  Bit Score: 104.85  E-value: 7.00e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  14 SRALKSDVKYSIYLPPKYDiETRKYPTIYLLHGhggneTSWLRKGRVDQSLDLMITNNEIPPFVAV-MPDA-KNSWYVNS 91
Cdd:pfam00756   1 SNSLGREMKVQVYLPEDYP-PGRKYPVLYLLDG-----TGWFQNGPAKEGLDRLAASGEIPPVIIVgSPRGgEVSFYSDW 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  92 PTGVN---------YETALIEDLLQHIETQYKVYneRSSRFIAGLSMGGYGALRLAFKYPELFLSVASLSGGITREVPPe 162
Cdd:pfam00756  75 DRGLNategpgayaYETFLTQELPPLLDANFPTA--PDGRALAGQSMGGLGALYLALKYPDLFGSVSSFSPILNPSNSM- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 163 kevdlygneihvredyyhdaFGWPFDPKFWE---KENIFNYIEHVKQsgleLPVYLSCGSEDYFYLYL----------GA 229
Cdd:pfam00756 152 --------------------WGPEDDPAWQEgdpVLLAVALSANNTR----LRIYLDVGTREDFLGDQlpveileelaPN 207

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1789698468 230 SELHHELRINGISSTLFIKPGDHNWFLWSQEIKDVLRFF 268
Cdd:pfam00756 208 RELAEQLAYRGVGGYDHEYYGGHDWAYWRAQLIAALIDL 246
COG4099 COG4099
Predicted peptidase [General function prediction only];
7-154 6.77e-21

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 88.49  E-value: 6.77e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468   7 YESLSFYSRALKSDVKYSIYLPPKYDiETRKYPTIYLLHGHGGNETSW---LRKGrvdqsLDLMITNNEIP--PFVAVMP 81
Cdd:COG4099    19 FEARTFTDPSDGDTLPYRLYLPKGYD-PGKKYPLVLFLHGAGERGTDNekqLTHG-----APKFINPENQAkfPAIVLAP 92

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1789698468  82 DA-KNSWYVNSPtgvnyETALIEDLLQHIETQYKVYNERssRFIAGLSMGGYGALRLAFKYPELFLSVASLSGG 154
Cdd:COG4099    93 QCpEDDYWSDTK-----ALDAVLALLDDLIAEYRIDPDR--IYLTGLSMGGYGTWDLAARYPDLFAAAVPICGG 159
YbbA COG2819
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
8-268 4.87e-15

Predicted hydrolase of the alpha/beta superfamily [General function prediction only];


Pssm-ID: 442067 [Multi-domain]  Cd Length: 250  Bit Score: 72.71  E-value: 4.87e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468   8 ESLSFYSRALKSDVKYSIYLPPKYDIETRKYPTIYLLHGHggnetsWLRKGRVDQSLDLMITNNEIPPFVAV-------- 79
Cdd:COG2819     8 EYFTLESPILGEDRRIRVYLPPGYDAPEKRYPVLYMLDGQ------NLFDALAGAVGTLSRLEGGIPPAIVVgigngddg 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  80 -------MPDAKNSWYVNSPT---GVNYETALIEDLLQHIETQYKVYNERssRFIAGLSMGGYGALRLAFKYPELFLSVA 149
Cdd:COG2819    82 errlrdyTPPPAPGYPGPGGPgggADAFLRFLEEELKPYIDKRYRTDPER--TGLIGHSLGGLFSLYALLKYPDLFGRYI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 150 SLSGGItrevppekevdlygneihvredyyhdafgWpfdpkfWEKENIFNYIE-HVKQSGLELPVYLSCGS---EDYFYL 225
Cdd:COG2819   160 AISPSL-----------------------------W------WDDGALLDEAEaLLKRSPLPKRLYLSVGTlegDSMDGM 204

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1789698468 226 YLGASELHHELR---INGISSTLFIKPG-DHNWFLWsQEIKDVLRFF 268
Cdd:COG2819   205 VDDARRLAEALKakgYPGLNVKFEVFPGeTHGSVAW-AALPRALRFL 250
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 23-153 2.35e-14

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 71.19  E-value: 2.35e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  23 YSIYLPPKYDiETRKYPTIYLLHGHGGNETSWLRKGRVDQSLDlmiTNNeippFVAVMPDA-----KNSWYVNSPT---- 93
Cdd:COG3509    39 YRLYVPAGYD-GGAPLPLVVALHGCGGSAADFAAGTGLNALAD---REG----FIVVYPEGtgrapGRCWNWFDGRdqrr 110

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  94 GVNyETALIEDLLQHIETQYKVynERSSRFIAGLSMGGYGALRLAFKYPELFLSVASLSG 153
Cdd:COG3509   111 GRD-DVAFIAALVDDLAARYGI--DPKRVYVTGLSAGGAMAYRLACEYPDVFAAVAPVAG 167
YpfH COG0400
Predicted esterase [General function prediction only];
34-270 1.00e-12

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 65.31  E-value: 1.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  34 ETRKYPTIYLLHGHGGNETSWLRKGRvdqSLDLmitnneiPPFVAVMPDAK-------NSWY-------VNSPTGVNYET 99
Cdd:COG0400     1 GGPAAPLVVLLHGYGGDEEDLLPLAP---ELAL-------PGAAVLAPRAPvpegpggRAWFdlsflegREDEEGLAAAA 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 100 ALIEDLLQHIETQYKVYNERssRFIAGLSMGGYGALRLAFKYPELFLSVASLSGGI-TREVPPEKEVDLYGneihvredy 178
Cdd:COG0400    71 EALAAFIDELEARYGIDPER--IVLAGFSQGAAMALSLALRRPELLAGVVALSGYLpGEEALPAPEAALAG--------- 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 179 yhdafgwpfdpkfwekenifnyiehvkqsgleLPVYLSCGSEDYFYLYLGASELHHELRINGISSTLFIKPGDHNWFlwS 258
Cdd:COG0400   140 --------------------------------TPVFLAHGTQDPVIPVERAREAAEALEAAGADVTYREYPGGHEIS--P 185

                         250
                  ....*....|..
gi 1789698468 259 QEIKDVLRFFAK 270
Cdd:COG0400   186 EELADARAWLAE 197
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
25-272 9.85e-12

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 63.11  E-value: 9.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  25 IYLPPKydieTRKYPTIYLLHGHGGNETS--------WLRKGrvdqsldlmitnneippFVAVMPDAKNSWYvnspTGVN 96
Cdd:COG1506    14 LYLPAD----GKKYPVVVYVHGGPGSRDDsflplaqaLASRG-----------------YAVLAPDYRGYGE----SAGD 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  97 YETALIEDL---LQHIETQYKVYNERssRFIAGLSMGGYGALRLAFKYPELFLSVASLSGGITREvppekevDLYGNEIH 173
Cdd:COG1506    69 WGGDEVDDVlaaIDYLAARPYVDPDR--IGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLR-------SYYGTTRE 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468 174 VREDYYhdaFGWPFDPKFWEKENIFNYIEHVKQsglelPVYLSCGSEDYFYLYLGASELHHELRINGISSTLFIKPG-DH 252
Cdd:COG1506   140 YTERLM---GGPWEDPEAYAARSPLAYADKLKT-----PLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGeGH 211

                         250       260
                  ....*....|....*....|...
gi 1789698468 253 nWFLWSQE---IKDVLRFFAKNM 272
Cdd:COG1506   212 -GFSGAGApdyLERILDFLDRHL 233
Esterase_PHB pfam10503
Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), ...
 23-153 1.48e-07

Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), feruloyl esterases (FAE), and poly(3-hydroxybutyrate) (PHB) depolymerases.


Pssm-ID: 431322 [Multi-domain]  Cd Length: 222  Bit Score: 50.83  E-value: 1.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  23 YSIYLPPKYDIETRKYPTIYLLHGHGGNETSWLRKGRVDQSLDLMitnneipPFVAVMPD------AKNSWYVNSPTGVN 96
Cdd:pfam10503   3 YALYLPPEAAGDGAPMPLVVMLHGCKQHADDFAAGTRINALADEL-------GFAVLYPEqskhahAHKCWNWFDEQGAA 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  97 Y---ETALIEDLLQHIETQYKVYNERSsrFIAGLSMGGYGALRLAFKYPELFLSVASLSG 153
Cdd:pfam10503  76 RgggEAASIAALAKAIAAAHRLDGARV--YLAGLSAGAALAALLAHCYPDVFAAVGLHSG 133
esterase_phb TIGR01840
esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ...
 76-154 3.21e-04

esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation]


Pssm-ID: 273828 [Multi-domain]  Cd Length: 212  Bit Score: 40.93  E-value: 3.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789698468  76 FVAVMPDAKNswYVNSPTGVNY-----------ETALIEDLLQHIETQYKVYNERssRFIAGLSMGGYGALRLAFKYPEL 144
Cdd:TIGR01840  44 FVLVAPEQTS--YNSSNNCWDWffthhrargtgEVESLHQLIDAVKANYSIDPNR--VYVTGLSAGGGMTAVLGCTYPDV 119

                          90
                  ....*....|
gi 1789698468 145 FLSVASLSGG 154
Cdd:TIGR01840 120 FAGGASNAGL 129
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
103-144 4.85e-03

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 37.61  E-value: 4.85e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1789698468 103 EDLLQHIETQYKVYNERSSR-FIAGLSMGGYGALRLAFKYPEL 144
Cdd:COG1647    66 EDWLEDVEEAYEILKAGYDKvIVIGLSMGGLLALLLAARYPDV 108
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 101-145 9.28e-03

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 36.81  E-value: 9.28e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1789698468 101 LIEDLLQHIETQYKVYnERSSRFIAGLSMGGYGALRLAFKYPELF 145
Cdd:pfam12146  58 YVDDLDTFVDKIREEH-PGLPLFLLGHSMGGLIAALYALRYPDKV 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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