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Conserved domains on  [gi|1767039313|ref|WP_151881261|]
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glycoside hydrolase family 2 TIM barrel-domain containing protein, partial [Bacteroides uniformis]

Protein Classification

beta-galactosidase( domain architecture ID 1000405)

beta-galactosidase catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides

CATH:  2.60.120.260|2.60.40.10|3.20.20.80|2.70.98.10
EC:  3.2.1.23

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Bgal_small_N super family cl46900
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 31-900 0e+00

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


The actual alignment was detected with superfamily member PRK09525:

Pssm-ID: 481240 [Multi-domain]  Cd Length: 1027  Bit Score: 704.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313   31 NPKLTSINREPARSTFTSYVTEADAVINdrKNGTFRLSLNGKWKFHYVETFADRPTDFMmdRVDASRWPDINVPGNWELQ 110
Cdd:PRK09525    19 NPGVTQLNRLPAHPPFASWRNSEAARDD--RPSQQRQSLNGEWRFSYFPAPEAVPESWL--ECDLPDADTIPVPSNWQLH 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  111 GFGTPIYVNQPYEFcssgyppywdkP-NPPYVPQEwNPTGTYRREFTLPGDW--DDKE--IFlsaDGVrGAAFY-YLNGK 184
Cdd:PRK09525    95 GYDAPIYTNVTYPI-----------PvNPPFVPEE-NPTGCYSLTFTVDESWlqSGQTriIF---DGV-NSAFHlWCNGR 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  185 FVGMSKDAKTPARFNVSAIAKKGKNVIAIQIHRFSDANYLECQDFWRISGIERDIYLYAQPQIHLTDFKVESPLDENYRN 264
Cdd:PRK09525   159 WVGYSQDSRLPAEFDLSPFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQLSDFHITTELDDDFRR 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  265 GILKVKVQFTNESGQNSpfLVGYRLLDkNDQQIAQSSTQVSG----------DQTEVEFTkktIQEPLQWTAETPNLYTL 334
Cdd:PRK09525   239 AVLEVEAQVNGELRDEL--RVTVQLWD-GETLVASGTAPFGTeiidergayaDRVTLRLN---VENPKLWSAETPNLYRA 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  335 VISLKRPNGDVIEATSCKVGFRTVEIKDKQLLVNGQPILVKGVNYHEHNENTGHYVSEELMKKDFELWKRYNVNTVRTCH 414
Cdd:PRK09525   313 VVSLLDADGTLIEAEAYDVGFRKVEIENGLLKLNGKPLLIRGVNRHEHHPEHGQVMDEETMVQDILLMKQHNFNAVRCSH 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  415 YPQQERFYELCDEYGIYVIDEANIESHGMGYDLRvggtLGNNPLFMNAHLDRTMNMYERDKNHPSVIIWSLGNEAGNGLN 494
Cdd:PRK09525   393 YPNHPLWYELCDRYGLYVVDEANIETHGMVPMNR----LSDDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGAN 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  495 FYVTYNTLKTLD-SRPIQYE------RAllewnTDIYCPMYAS----------PSY-LEKYARNKEMTRPLILCEYAHAM 556
Cdd:PRK09525   469 HDALYRWIKSNDpSRPVQYEgggadtAA-----TDIICPMYARvdedqpfpavPKWsIKKWISLPGETRPLILCEYAHAM 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  557 GNSLGNFQEYWDIIEKYPILQGGCVWDWVDQGFAAKTDDGRKYWTYGGDYGEngTPSDGNFCINGVVYPDRSVKPQTEEM 636
Cdd:PRK09525   544 GNSLGGFAKYWQAFRQYPRLQGGFIWDWVDQGLTKYDENGNPWWAYGGDFGD--TPNDRQFCMNGLVFPDRTPHPALYEA 621

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  637 GKVYQNIKFLDFDKQTSTVKIRNDFSFTNLDKYDFYYIIRDHGKEVYRGKIeNIHAAPG--KTVTTGFLNGIPKEKQTTG 714
Cdd:PRK09525   622 KHAQQFFQFSLLSTTPLTIEVTSEYLFRHSDNELLHWSVALDGKPLASGEV-PLDLAPQgsQRITLPELPQPESAGQLWL 700

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  715 DVRIEfyaaIKTAEPFLPAGTVIAREQtyvHTFYKKEATAQQPATS-----KEEGNLVAFSGPDFKATFDKQSGLLTSYL 789
Cdd:PRK09525   701 NVEVV----QPNATAWSEAGHRSAWQQ---WRLPEPLSLPLPTASHaapqlTQDEQDFCIELGNQRWQFNRQSGLLSQWW 773

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  790 YKKHEYILngQGPRPFFWRAPTDNDYGANLPVRL------KAWKEAS-YQ-EPKAESFQVTPGSNATTVKVTYRF----- 856
Cdd:PRK09525   774 VGGKEQLL--TPLRDQFTRAPLDNDIGVSEATRIdpnawvERWKAAGlYQlEARLLQCDADTLADAVLITTEHAYqhqgk 851

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....
gi 1767039313  857 PQTEARWniTYKIYASGVIKVDNRFMAEGDQAPMiPRVGLRMQL 900
Cdd:PRK09525   852 TLFISRK--TYRIDGQGEMTIDVDVEVASDLPPP-ARIGLTCQL 892
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
31-900 0e+00

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 704.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313   31 NPKLTSINREPARSTFTSYVTEADAVINdrKNGTFRLSLNGKWKFHYVETFADRPTDFMmdRVDASRWPDINVPGNWELQ 110
Cdd:PRK09525    19 NPGVTQLNRLPAHPPFASWRNSEAARDD--RPSQQRQSLNGEWRFSYFPAPEAVPESWL--ECDLPDADTIPVPSNWQLH 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  111 GFGTPIYVNQPYEFcssgyppywdkP-NPPYVPQEwNPTGTYRREFTLPGDW--DDKE--IFlsaDGVrGAAFY-YLNGK 184
Cdd:PRK09525    95 GYDAPIYTNVTYPI-----------PvNPPFVPEE-NPTGCYSLTFTVDESWlqSGQTriIF---DGV-NSAFHlWCNGR 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  185 FVGMSKDAKTPARFNVSAIAKKGKNVIAIQIHRFSDANYLECQDFWRISGIERDIYLYAQPQIHLTDFKVESPLDENYRN 264
Cdd:PRK09525   159 WVGYSQDSRLPAEFDLSPFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQLSDFHITTELDDDFRR 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  265 GILKVKVQFTNESGQNSpfLVGYRLLDkNDQQIAQSSTQVSG----------DQTEVEFTkktIQEPLQWTAETPNLYTL 334
Cdd:PRK09525   239 AVLEVEAQVNGELRDEL--RVTVQLWD-GETLVASGTAPFGTeiidergayaDRVTLRLN---VENPKLWSAETPNLYRA 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  335 VISLKRPNGDVIEATSCKVGFRTVEIKDKQLLVNGQPILVKGVNYHEHNENTGHYVSEELMKKDFELWKRYNVNTVRTCH 414
Cdd:PRK09525   313 VVSLLDADGTLIEAEAYDVGFRKVEIENGLLKLNGKPLLIRGVNRHEHHPEHGQVMDEETMVQDILLMKQHNFNAVRCSH 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  415 YPQQERFYELCDEYGIYVIDEANIESHGMGYDLRvggtLGNNPLFMNAHLDRTMNMYERDKNHPSVIIWSLGNEAGNGLN 494
Cdd:PRK09525   393 YPNHPLWYELCDRYGLYVVDEANIETHGMVPMNR----LSDDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGAN 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  495 FYVTYNTLKTLD-SRPIQYE------RAllewnTDIYCPMYAS----------PSY-LEKYARNKEMTRPLILCEYAHAM 556
Cdd:PRK09525   469 HDALYRWIKSNDpSRPVQYEgggadtAA-----TDIICPMYARvdedqpfpavPKWsIKKWISLPGETRPLILCEYAHAM 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  557 GNSLGNFQEYWDIIEKYPILQGGCVWDWVDQGFAAKTDDGRKYWTYGGDYGEngTPSDGNFCINGVVYPDRSVKPQTEEM 636
Cdd:PRK09525   544 GNSLGGFAKYWQAFRQYPRLQGGFIWDWVDQGLTKYDENGNPWWAYGGDFGD--TPNDRQFCMNGLVFPDRTPHPALYEA 621

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  637 GKVYQNIKFLDFDKQTSTVKIRNDFSFTNLDKYDFYYIIRDHGKEVYRGKIeNIHAAPG--KTVTTGFLNGIPKEKQTTG 714
Cdd:PRK09525   622 KHAQQFFQFSLLSTTPLTIEVTSEYLFRHSDNELLHWSVALDGKPLASGEV-PLDLAPQgsQRITLPELPQPESAGQLWL 700

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  715 DVRIEfyaaIKTAEPFLPAGTVIAREQtyvHTFYKKEATAQQPATS-----KEEGNLVAFSGPDFKATFDKQSGLLTSYL 789
Cdd:PRK09525   701 NVEVV----QPNATAWSEAGHRSAWQQ---WRLPEPLSLPLPTASHaapqlTQDEQDFCIELGNQRWQFNRQSGLLSQWW 773

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  790 YKKHEYILngQGPRPFFWRAPTDNDYGANLPVRL------KAWKEAS-YQ-EPKAESFQVTPGSNATTVKVTYRF----- 856
Cdd:PRK09525   774 VGGKEQLL--TPLRDQFTRAPLDNDIGVSEATRIdpnawvERWKAAGlYQlEARLLQCDADTLADAVLITTEHAYqhqgk 851

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....
gi 1767039313  857 PQTEARWniTYKIYASGVIKVDNRFMAEGDQAPMiPRVGLRMQL 900
Cdd:PRK09525   852 TLFISRK--TYRIDGQGEMTIDVDVEVASDLPPP-ARIGLTCQL 892
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
71-647 2.29e-173

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 517.01  E-value: 2.29e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  71 GKWKFHYVETFADRPTDFmmdrvDASRWPDINVPGNWELQGFGTPiyvnqpyefcssgyppywdkpnPPYVPQE--WNPT 148
Cdd:COG3250     1 GGWKFRLGDAPEGAKPDF-----DDSGWDPITVPGDWELDLYGLP----------------------DPFVGPWylYNGV 53

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 149 GTYRREFTLPGDWDDKEIFLSADGVRGAAFYYLNGKFVGMSKDAKTPARFNVSAIAKKGKNVIAIQIHRFSDANYLECQD 228
Cdd:COG3250    54 GWYRRTFTVPASWKGKRVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLKPGENVLAVRVDNPSDGSYLEGQD 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 229 FWRISGIERDIYLYAQPQIHLTDFKVESPLDEnyRNGILKVKVQFTNESGQnsPFLVGYRLLDKNDQQIAQSSTQVS--- 305
Cdd:COG3250   134 WWRTSGIYRDVWLEATPKVHIEDVFVTPDLDD--GSATLTVEVELENESDA--GVTVEVTLLDADGKVVATATAKVTlaa 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 306 GDQTEVEFTkKTIQEPLQWTAETPNLYTLVISLKRpNGDVIEATSCKVGFRTVEIKD-KQLLVNGQPILVKGVNYHEHNE 384
Cdd:COG3250   210 GEENTVTLT-LTVPNPKLWSPEDPNLYTLVVTLKD-DGKVVDTVSTRFGFRTIEIDGdGGFLLNGKPVFLKGVNRHEDWP 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 385 NTGHYVSEELMKKDFELWKRYNVNTVRTCHYPQQERFYELCDEYGIYVIDEANIESHGMgydlrvggtLGNNPLFMNAHL 464
Cdd:COG3250   288 DDGRAVTDEAMRRDLELMKEAGFNAVRTSHYPEDPEFYDLCDELGLLVWDEAPFEWHGM---------LGDDPEFLEAVE 358

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 465 DRTMNMYERDKNHPSVIIWSLGNEAGNGLNFYVTYNTLKTLD-SRPIqyerallewntdiycpmyaspsylekyarnkem 543
Cdd:COG3250   359 AELREMVRRDRNHPSIILWSGGNESGGGPNFAALYEWVKELDpTRPV--------------------------------- 405

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 544 trpLILCEYAHAMGNSLGN----------------FQEYWDIIEKYPILQGGCVWDWVDqgfaaktddgrkYWTYggdyg 607
Cdd:COG3250   406 ---RFLSEYGHAMPNSLGGgyhqpsdfeeyqalqaLEEYWEAFRRRPRLAGGFIWQLND------------YWPE----- 465

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 1767039313 608 enGTPSDGNFCINGVV-YPDRSVKPQTEEMGKVYQNIKFLD 647
Cdd:COG3250   466 --PRDNDGNFCSWGLVdYYDRTPKPAYYEVKSAWQPVLVSD 504
Glyco_hydro_2_C pfam02836
Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, ...
 358-645 3.76e-100

Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 397119 [Multi-domain]  Cd Length: 302  Bit Score: 314.39  E-value: 3.76e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 358 VEIKDKQLLVNGQPILVKGVNYHEHNENTGHYVSEELMKKDFELWKRYNVNTVRTCHYPQQERFYELCDEYGIYVIDEAN 437
Cdd:pfam02836   1 VEVKDGLFLINGKPFYFRGVNRHEDHDRRGRGFDMDLMVKDIQLMKQNNINAVRTSHYPNHPEWYQLCDEYGIYVIDEAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 438 IESHGMGYDLRVGGTLGN----NPLFMNAHLDRTMNMYERDKNHPSVIIWSLGNEAGNGLNFYVTYNTLKTLD-SRPIQY 512
Cdd:pfam02836  81 LETHGLWQKFGEIEPSYSeltdNPEWLPAHLERAEELVQRDKNHPSVIIWSLGNESGAGENIAAMYAATKSLDpTRPVHY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 513 ERALLEWN-TDIYCPMYAS-------PSYLEKY--ARNKEMTRPLILCEYAHAMGNSLGNFQEYWDIIEKYPILQGGCVW 582
Cdd:pfam02836 161 EGVGIDPEvDDIILDIYSRmyedyghPEVIEKYleDWYKKPQKPIIICEYGHAMGNSPGGLQEYQDLFYKYPEYQGGFIW 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1767039313 583 DWVDQGFAAKTD--DGRKYWtYGGDYGENgtPSDGNFCINGVVYPDRSVKPQTEEMGKVYQNIKF 645
Cdd:pfam02836 241 DWHDQGIQKRDPnvGGEWYW-YGGDFGDR--PSDYRFCGNGLFFADRTPKPALFELKKRYWPIKI 302
Bgal_small_N smart01038
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 770-900 2.39e-36

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 214988 [Multi-domain]  Cd Length: 272  Bit Score: 138.49  E-value: 2.39e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  770 SGPDFKATFDKQSGLLTSYLYKKHEYILngQGPRPFFWRAPTDNDYGANLPVRLKAWKEASYQ--EPKAESFQVTPGSNA 847
Cdd:smart01038   1 SGGGFSYTFDKATGALTSWTYNGKELLL--RGPKPNFWRAPTDNDRGNGPNAWAARWKAAGLDrlTTRVRSVEVEQDSDV 78

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1767039313  848 tTVKVTYRFP---QTEARWNITYKIYASGVIKVDNRFMAEGDQAPMIPRVGLRMQL 900
Cdd:smart01038  79 -VVTVEYLLAapsGWGFTVTVTYTIDGDGEVKVDVTFTPGGGALPDLPRIGLRFRL 133
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
31-900 0e+00

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 704.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313   31 NPKLTSINREPARSTFTSYVTEADAVINdrKNGTFRLSLNGKWKFHYVETFADRPTDFMmdRVDASRWPDINVPGNWELQ 110
Cdd:PRK09525    19 NPGVTQLNRLPAHPPFASWRNSEAARDD--RPSQQRQSLNGEWRFSYFPAPEAVPESWL--ECDLPDADTIPVPSNWQLH 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  111 GFGTPIYVNQPYEFcssgyppywdkP-NPPYVPQEwNPTGTYRREFTLPGDW--DDKE--IFlsaDGVrGAAFY-YLNGK 184
Cdd:PRK09525    95 GYDAPIYTNVTYPI-----------PvNPPFVPEE-NPTGCYSLTFTVDESWlqSGQTriIF---DGV-NSAFHlWCNGR 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  185 FVGMSKDAKTPARFNVSAIAKKGKNVIAIQIHRFSDANYLECQDFWRISGIERDIYLYAQPQIHLTDFKVESPLDENYRN 264
Cdd:PRK09525   159 WVGYSQDSRLPAEFDLSPFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQLSDFHITTELDDDFRR 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  265 GILKVKVQFTNESGQNSpfLVGYRLLDkNDQQIAQSSTQVSG----------DQTEVEFTkktIQEPLQWTAETPNLYTL 334
Cdd:PRK09525   239 AVLEVEAQVNGELRDEL--RVTVQLWD-GETLVASGTAPFGTeiidergayaDRVTLRLN---VENPKLWSAETPNLYRA 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  335 VISLKRPNGDVIEATSCKVGFRTVEIKDKQLLVNGQPILVKGVNYHEHNENTGHYVSEELMKKDFELWKRYNVNTVRTCH 414
Cdd:PRK09525   313 VVSLLDADGTLIEAEAYDVGFRKVEIENGLLKLNGKPLLIRGVNRHEHHPEHGQVMDEETMVQDILLMKQHNFNAVRCSH 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  415 YPQQERFYELCDEYGIYVIDEANIESHGMGYDLRvggtLGNNPLFMNAHLDRTMNMYERDKNHPSVIIWSLGNEAGNGLN 494
Cdd:PRK09525   393 YPNHPLWYELCDRYGLYVVDEANIETHGMVPMNR----LSDDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGAN 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  495 FYVTYNTLKTLD-SRPIQYE------RAllewnTDIYCPMYAS----------PSY-LEKYARNKEMTRPLILCEYAHAM 556
Cdd:PRK09525   469 HDALYRWIKSNDpSRPVQYEgggadtAA-----TDIICPMYARvdedqpfpavPKWsIKKWISLPGETRPLILCEYAHAM 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  557 GNSLGNFQEYWDIIEKYPILQGGCVWDWVDQGFAAKTDDGRKYWTYGGDYGEngTPSDGNFCINGVVYPDRSVKPQTEEM 636
Cdd:PRK09525   544 GNSLGGFAKYWQAFRQYPRLQGGFIWDWVDQGLTKYDENGNPWWAYGGDFGD--TPNDRQFCMNGLVFPDRTPHPALYEA 621

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  637 GKVYQNIKFLDFDKQTSTVKIRNDFSFTNLDKYDFYYIIRDHGKEVYRGKIeNIHAAPG--KTVTTGFLNGIPKEKQTTG 714
Cdd:PRK09525   622 KHAQQFFQFSLLSTTPLTIEVTSEYLFRHSDNELLHWSVALDGKPLASGEV-PLDLAPQgsQRITLPELPQPESAGQLWL 700

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  715 DVRIEfyaaIKTAEPFLPAGTVIAREQtyvHTFYKKEATAQQPATS-----KEEGNLVAFSGPDFKATFDKQSGLLTSYL 789
Cdd:PRK09525   701 NVEVV----QPNATAWSEAGHRSAWQQ---WRLPEPLSLPLPTASHaapqlTQDEQDFCIELGNQRWQFNRQSGLLSQWW 773

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  790 YKKHEYILngQGPRPFFWRAPTDNDYGANLPVRL------KAWKEAS-YQ-EPKAESFQVTPGSNATTVKVTYRF----- 856
Cdd:PRK09525   774 VGGKEQLL--TPLRDQFTRAPLDNDIGVSEATRIdpnawvERWKAAGlYQlEARLLQCDADTLADAVLITTEHAYqhqgk 851

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....
gi 1767039313  857 PQTEARWniTYKIYASGVIKVDNRFMAEGDQAPMiPRVGLRMQL 900
Cdd:PRK09525   852 TLFISRK--TYRIDGQGEMTIDVDVEVASDLPPP-ARIGLTCQL 892
ebgA PRK10340
cryptic beta-D-galactosidase subunit alpha; Reviewed
 31-900 0e+00

cryptic beta-D-galactosidase subunit alpha; Reviewed


Pssm-ID: 236673 [Multi-domain]  Cd Length: 1021  Bit Score: 674.85  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313   31 NPKLTSINREPARSTFTSYVTEADAVINDRKNGTFRLSLNGKWKFHYVETFADRPTDFMmdRVDASRWPDINVPGNWELQ 110
Cdd:PRK10340     6 NIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLLLSGQWNFHFFDHPLYVPEAFT--SELMSDWGHITVPAMWQME 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  111 GFGTPIYVNQPYEFcssgyppywdkP-NPPYVPQEwNPTGTYRREFTLPGDWDDKEIFLSADGVRGAAFYYLNGKFVGMS 189
Cdd:PRK10340    84 GHGKLQYTDEGFPF-----------PiDVPFVPSD-NPTGAYQRTFTLSDGWQGKQTIIKFDGVETYFEVYVNGQYVGFS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  190 KDAKTPARFNVSAIAKKGKNVIAIQIHRFSDANYLECQDFWRISGIERDIYLYAQPQIHLTDFKVESPLDENYRNGILKV 269
Cdd:PRK10340   152 KGSRLTAEFDISAMVKTGDNLLCVRVMQWADSTYLEDQDMWWLAGIFRDVYLVGKPLTHINDFTVRTDFDEDYCDATLSC 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  270 KVQFTNESGQNSPFLVGYRLLDKNDQQIAQSSTQVSGD-QTEVEFTKkTIQEPLQWTAETPNLYTLVISLKRPNGDVIEA 348
Cdd:PRK10340   232 EVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEkLTSASFAF-TVEQPQQWSAESPYLYHLVMTLKDANGNVLEV 310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  349 TSCKVGFRTVEIKDKQLLVNGQPILVKGVNYHEHNENTGHYVSEELMKKDFELWKRYNVNTVRTCHYPQQERFYELCDEY 428
Cdd:PRK10340   311 VPQRVGFRDIKVRDGLFWINNRYVKLHGVNRHDNDHRKGRAVGMDRVEKDIQLMKQHNINSVRTAHYPNDPRFYELCDIY 390

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  429 GIYVIDEANIESHGMG----YDlrvggTLGNNPLFMNAHLDRTMNMYERDKNHPSVIIWSLGNEAGNGLNFYVTYNTLKT 504
Cdd:PRK10340   391 GLFVMAETDVESHGFAnvgdIS-----RITDDPQWEKVYVDRIVRHIHAQKNHPSIIIWSLGNESGYGCNIRAMYHAAKA 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  505 LD-SRPIQYERALLEWNTDIYCPMYASPSYLEKYARNkEMTRPLILCEYAHAMGNSLGNFQEYWDIIEKYPILQGGCVWD 583
Cdd:PRK10340   466 LDdTRLVHYEEDRDAEVVDVISTMYTRVELMNEFGEY-PHPKPRILCEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWE 544

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  584 WVDQGFAAKTDDGRKYWTYGGDYGENgtPSDGNFCINGVVYPDRSVKPQTEEMGKVYQNIKFLDFDKQTSTVKIRNDFSF 663
Cdd:PRK10340   545 WCDHGIQAQDDNGNVWYKYGGDYGDY--PNNYNFCIDGLIYPDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWF 622

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  664 TNLDKYDFYYIIRDHGKEVYRGKIENIHAAPGKTVTTgflnGIPKEKQTTGDVRIEFYAAIKTAEPFLPAGTVIAREQty 743
Cdd:PRK10340   623 TNLDDYTLHAEVRAEGETLASGQIKLRDVAPNSEAPL----QITLPQLDAREAFLNITVTKDSRTRYSEAGHSIATYQ-- 696

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  744 vhtFYKKEATAQ------QPATS---KEEGNLVAFSGPDFKATFDKQSGLLTSYLYKKHEYILNgqGPRPFFWRAPTDND 814
Cdd:PRK10340   697 ---FPLKENTAQpvpfapNNARPltlEEDRLSCTVRGYNFAITFSKVSGKLTSWQVNGESLLTR--EPKINFFKPMIDNH 771

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  815 Y----GANLPVRLKAWKEasyqepKAESFQVTPGSNATTVKVTYRFPQTEARW--NIT--YKIYASGVIKVDNRFMAEGD 886
Cdd:PRK10340   772 KqeyeGLWQPNHLQIMQE------HLRDFAVEQSDGEVLIISRTVIAPPVFDFgmRCTyiYRIAADGQVNVALSGERYGD 845

                          890
                   ....*....|....
gi 1767039313  887 QAPMIPRVGLRMQL 900
Cdd:PRK10340   846 YPHMIPCIGFTMGI 859
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
71-647 2.29e-173

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 517.01  E-value: 2.29e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  71 GKWKFHYVETFADRPTDFmmdrvDASRWPDINVPGNWELQGFGTPiyvnqpyefcssgyppywdkpnPPYVPQE--WNPT 148
Cdd:COG3250     1 GGWKFRLGDAPEGAKPDF-----DDSGWDPITVPGDWELDLYGLP----------------------DPFVGPWylYNGV 53

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 149 GTYRREFTLPGDWDDKEIFLSADGVRGAAFYYLNGKFVGMSKDAKTPARFNVSAIAKKGKNVIAIQIHRFSDANYLECQD 228
Cdd:COG3250    54 GWYRRTFTVPASWKGKRVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLKPGENVLAVRVDNPSDGSYLEGQD 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 229 FWRISGIERDIYLYAQPQIHLTDFKVESPLDEnyRNGILKVKVQFTNESGQnsPFLVGYRLLDKNDQQIAQSSTQVS--- 305
Cdd:COG3250   134 WWRTSGIYRDVWLEATPKVHIEDVFVTPDLDD--GSATLTVEVELENESDA--GVTVEVTLLDADGKVVATATAKVTlaa 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 306 GDQTEVEFTkKTIQEPLQWTAETPNLYTLVISLKRpNGDVIEATSCKVGFRTVEIKD-KQLLVNGQPILVKGVNYHEHNE 384
Cdd:COG3250   210 GEENTVTLT-LTVPNPKLWSPEDPNLYTLVVTLKD-DGKVVDTVSTRFGFRTIEIDGdGGFLLNGKPVFLKGVNRHEDWP 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 385 NTGHYVSEELMKKDFELWKRYNVNTVRTCHYPQQERFYELCDEYGIYVIDEANIESHGMgydlrvggtLGNNPLFMNAHL 464
Cdd:COG3250   288 DDGRAVTDEAMRRDLELMKEAGFNAVRTSHYPEDPEFYDLCDELGLLVWDEAPFEWHGM---------LGDDPEFLEAVE 358

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 465 DRTMNMYERDKNHPSVIIWSLGNEAGNGLNFYVTYNTLKTLD-SRPIqyerallewntdiycpmyaspsylekyarnkem 543
Cdd:COG3250   359 AELREMVRRDRNHPSIILWSGGNESGGGPNFAALYEWVKELDpTRPV--------------------------------- 405

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 544 trpLILCEYAHAMGNSLGN----------------FQEYWDIIEKYPILQGGCVWDWVDqgfaaktddgrkYWTYggdyg 607
Cdd:COG3250   406 ---RFLSEYGHAMPNSLGGgyhqpsdfeeyqalqaLEEYWEAFRRRPRLAGGFIWQLND------------YWPE----- 465

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 1767039313 608 enGTPSDGNFCINGVV-YPDRSVKPQTEEMGKVYQNIKFLD 647
Cdd:COG3250   466 --PRDNDGNFCSWGLVdYYDRTPKPAYYEVKSAWQPVLVSD 504
Glyco_hydro_2_C pfam02836
Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, ...
 358-645 3.76e-100

Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 397119 [Multi-domain]  Cd Length: 302  Bit Score: 314.39  E-value: 3.76e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 358 VEIKDKQLLVNGQPILVKGVNYHEHNENTGHYVSEELMKKDFELWKRYNVNTVRTCHYPQQERFYELCDEYGIYVIDEAN 437
Cdd:pfam02836   1 VEVKDGLFLINGKPFYFRGVNRHEDHDRRGRGFDMDLMVKDIQLMKQNNINAVRTSHYPNHPEWYQLCDEYGIYVIDEAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 438 IESHGMGYDLRVGGTLGN----NPLFMNAHLDRTMNMYERDKNHPSVIIWSLGNEAGNGLNFYVTYNTLKTLD-SRPIQY 512
Cdd:pfam02836  81 LETHGLWQKFGEIEPSYSeltdNPEWLPAHLERAEELVQRDKNHPSVIIWSLGNESGAGENIAAMYAATKSLDpTRPVHY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 513 ERALLEWN-TDIYCPMYAS-------PSYLEKY--ARNKEMTRPLILCEYAHAMGNSLGNFQEYWDIIEKYPILQGGCVW 582
Cdd:pfam02836 161 EGVGIDPEvDDIILDIYSRmyedyghPEVIEKYleDWYKKPQKPIIICEYGHAMGNSPGGLQEYQDLFYKYPEYQGGFIW 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1767039313 583 DWVDQGFAAKTD--DGRKYWtYGGDYGENgtPSDGNFCINGVVYPDRSVKPQTEEMGKVYQNIKF 645
Cdd:pfam02836 241 DWHDQGIQKRDPnvGGEWYW-YGGDFGDR--PSDYRFCGNGLFFADRTPKPALFELKKRYWPIKI 302
PRK10150 PRK10150
beta-D-glucuronidase; Provisional
 151-489 1.30e-46

beta-D-glucuronidase; Provisional


Pssm-ID: 236657 [Multi-domain]  Cd Length: 604  Bit Score: 176.73  E-value: 1.30e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 151 YRREFTLPGDWDDKEIFLSADGVRGAAFYYLNGKFVGMSKDAKTPARFNVSAIAKKGKNVIAI----------------- 213
Cdd:PRK10150   69 YQREVFIPKGWAGQRIVLRFGSVTHYAKVWVNGQEVMEHKGGYTPFEADITPYVYAGKSVRITvcvnnelnwqtlppgnv 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 214 ----QIHRFSDANYlecqDFWRISGIERDIYLYAQPQIHLTDFKVESPLDENYRNGILKVKVQftnESGQNSPFLVgyRL 289
Cdd:PRK10150  149 iedgNGKKKQKYNF----DFFNYAGIHRPVMLYTTPKTHIDDITVVTELAQDLNHASVDWSVE---TNGDVDSVSV--TL 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 290 LDKnDQQIAQSSTQVSGdqteveftKKTIQEPLQWTAETPNLYTLVISLKRpNGDVIEATSCKVGFRTVEIKDKQLLVNG 369
Cdd:PRK10150  220 RDA-DGQVVATGQGTSG--------TLQVVNPHLWQPGEGYLYTLCVELAK-SGTECDTYPLRFGIRSVAVKGGQFLING 289

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 370 QPILVKGVNYHEHNENTGHYVSEELMKKDFELWKRYNVNTVRTCHYPQQERFYELCDEYGIYVIDEANieshGMGYDLRV 449
Cdd:PRK10150  290 KPFYFKGFGKHEDADIRGKGLDEVLNVHDHNLMKWIGANSFRTSHYPYSEEMLDLADRHGIVVIDETP----AVGLNLSF 365

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1767039313 450 GGTLG----NNPLF---------MNAHLDRTMNMYERDKNHPSVIIWSLGNEA 489
Cdd:PRK10150  366 GAGLEagnkPKETYseeavngetQQAHLQAIRELIARDKNHPSVVMWSIANEP 418
Bgal_small_N smart01038
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 770-900 2.39e-36

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 214988 [Multi-domain]  Cd Length: 272  Bit Score: 138.49  E-value: 2.39e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  770 SGPDFKATFDKQSGLLTSYLYKKHEYILngQGPRPFFWRAPTDNDYGANLPVRLKAWKEASYQ--EPKAESFQVTPGSNA 847
Cdd:smart01038   1 SGGGFSYTFDKATGALTSWTYNGKELLL--RGPKPNFWRAPTDNDRGNGPNAWAARWKAAGLDrlTTRVRSVEVEQDSDV 78

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1767039313  848 tTVKVTYRFP---QTEARWNITYKIYASGVIKVDNRFMAEGDQAPMIPRVGLRMQL 900
Cdd:smart01038  79 -VVTVEYLLAapsGWGFTVTVTYTIDGDGEVKVDVTFTPGGGALPDLPRIGLRFRL 133
Glyco_hydro_2_N pfam02837
Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, ...
 68-245 7.82e-32

Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.


Pssm-ID: 397120 [Multi-domain]  Cd Length: 169  Bit Score: 121.97  E-value: 7.82e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313  68 SLNGKWKFHYVETFADRPTDFMMDRVDASRwpDINVPGNWELQgfgtPIYVNQPYefcssgyPPYWDKPNPPYVpqewNP 147
Cdd:pfam02837   3 SLNGEWAFALFDAPCGAPQSWWESALQESR--TIAVPSSWNDQ----PIYTNVEY-------PIDFADPFIPTY----NG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 148 TGTYRREFTLPGDWDDKEIFLSADGVRGAAFYYLNGKFVGMSKDAKTPARFNVSAIAKKGKNVIAIQIHRFSDANYLECQ 227
Cdd:pfam02837  66 TGWYQRTFFIPSKWAGQRIRLRFDGVTHYGEVWVNGQWVGEHQGGYTPFEFDLTPYVIAGKNRIAVKVLNWSDG*YIEDQ 145

                         170       180
                  ....*....|....*....|....
gi 1767039313 228 ------DFWRISGIERDIYLYAQP 245
Cdd:pfam02837 146 ngkyfhDFWNYSGIYRDVSLLTTP 169
Bgal_small_N pfam02929
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 770-900 3.54e-21

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 460751  Cd Length: 223  Bit Score: 92.94  E-value: 3.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 770 SGPDFKATFDKQSGLLTSYLYKKHEYILNGQGPRPFFWRAPTDNDYganlpvrlkawkeasyqepkaesfqvtpgsnatt 849
Cdd:pfam02929   1 SGGDFSYTFDKATGTLTSYKYDGKELLTEPLTGRPNFWRAPTDNDV---------------------------------- 46

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1767039313 850 vkvtyrfpqtearwNITYKIYASGVIKVDNRFMAEGDQA-PMIPRVGLRMQL 900
Cdd:pfam02929  47 --------------TVTYTIYGDGTIKVDVTLKPDGLKGlPELPRFGLRLQL 84
Glyco_hydro_2 pfam00703
Glycosyl hydrolases family 2; This family contains beta-galactosidase, beta-mannosidase and ...
 247-356 9.53e-17

Glycosyl hydrolases family 2; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 395572 [Multi-domain]  Cd Length: 106  Bit Score: 76.75  E-value: 9.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 247 IHLTDFKVESPLDENyRNGILKVKVQFTNESGQNSPFLVGYRLLDKNDQQIAQSSTQVSgdQTEVEFTKKTIQEPLQWTA 326
Cdd:pfam00703   1 VHIEDVFITPDLDDD-KTAKVTVEVELENDGDASVEVTLETEIKDADGKTVAAAAKVLV--LGAGETTELEVKNPKLWSP 77

                          90       100       110
                  ....*....|....*....|....*....|
gi 1767039313 327 ETPNLYTLVISLKRpNGDVIEATSCKVGFR 356
Cdd:pfam00703  78 ETPNLYTLTVELDK-DGKVIDEVSTRFGFR 106
LacZ_4 pfam16353
Beta-galactosidase, domain 4; This entry represents domain 4 found in beta-galactosidase and ...
 655-741 1.58e-15

Beta-galactosidase, domain 4; This entry represents domain 4 found in beta-galactosidase and it is organized in a jelly-roll type barrel (Rutkiewicz-Krotewicz M. et al. Crystals 2018, 8(1), 13, https://doi.org/10.3390/cryst8010013).


Pssm-ID: 465101 [Multi-domain]  Cd Length: 88  Bit Score: 72.60  E-value: 1.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1767039313 655 VKIRNDFSFTNLDKYDFYYIIRDHGKEVYRGKIENIHAAPGKTVTTgflnGIP-KEKQTTGDVRIEFYAAIKTAEPFLPA 733
Cdd:pfam16353   1 VTITNRYDFTDLDDYDLSWELLADGKVVASGTLELPDVAPGESATV----TLPlPLPGLAGEYFLTVSFRLKEDTPWAPA 76


                  ....*...
gi 1767039313 734 GTVIAREQ 741
Cdd:pfam16353  77 GHEVAWEQ 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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