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Conserved domains on  [gi|1750418682|ref|WP_150014964|]
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MULTISPECIES: EAL domain-containing protein [Pantoea]

Protein Classification

EAL domain-containing protein( domain architecture ID 11471819)

EAL domain-containing protein may act as a cyclic diguanylate phosphodiesterase, similar to Escherichia coli putative cyclic-di-GMP phosphodiesterases YjcC and YlaB

Gene Ontology:  GO:0007165

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 10-520 2.67e-151

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


:

Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 442.82  E-value: 2.67e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  10 QFRRKRL-----LIALSIATVVLILTLAFRYIEEKSRIEQQAMDFADKAIMRFDRMFSPLEVSASNTLGLVGAPCQDV-R 83
Cdd:COG4943     2 RMRRRRLlslatLLALLAALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSALDELNALPGDPCSPAhL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  84 FPLIEKISSLQTVRAILLVENDMLYCSSIyGPRNIPFSQTYPD-LAFNSQRMTLATDEYLLKGSPILLLWtpksldnRSG 162
Cdd:COG4943    82 AALRRLVFSSRYVRDIGYVRDGRLLCSSL-GKLSKPVPLPPPDyVTADGYRLWLNVDNPLDPGRPMLIVG-------RGN 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 163 ILQVINIEMMSNYLLEPqlPWVERAVFNVNGESLEYGNPLIEPTV------------PSDDEVSYEQGSLRYPFTLTLYG 230
Cdd:COG4943   154 YVVVIDPAAFIDVLSPQ--PGISLALLATNGGHLFASSGNPDPALlsrllrgpsswfIQGDRLYASACSPQYPICVVAAA 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 231 PSPTRLALATLPSQLPLAL--LLSLLMGYIIWLATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHN 308
Cdd:COG4943   232 PLAGLLALWRQLLLLLLPLglLLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRD 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 309 ARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQ-LPDDSAFHIAINVAASHFRDRAILEDLQNLWWPAS-PVPQL 386
Cdd:COG4943   312 PDGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDlLAADPDFHISINLSASDLLSPRFLDDLERLLARTGvAPQQI 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 387 VVELTERDALPVVD-QSVIAQLHEIGVRLAIDDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQ 465
Cdd:COG4943   392 VLEITERGFIDPAKaRAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAK 471

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1750418682 466 RLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLEDFPAWLTRHQADARR 520
Cdd:COG4943   472 TLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAKPLPAEEFIAWLAAQRAPASA 526
 
Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 10-520 2.67e-151

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 442.82  E-value: 2.67e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  10 QFRRKRL-----LIALSIATVVLILTLAFRYIEEKSRIEQQAMDFADKAIMRFDRMFSPLEVSASNTLGLVGAPCQDV-R 83
Cdd:COG4943     2 RMRRRRLlslatLLALLAALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSALDELNALPGDPCSPAhL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  84 FPLIEKISSLQTVRAILLVENDMLYCSSIyGPRNIPFSQTYPD-LAFNSQRMTLATDEYLLKGSPILLLWtpksldnRSG 162
Cdd:COG4943    82 AALRRLVFSSRYVRDIGYVRDGRLLCSSL-GKLSKPVPLPPPDyVTADGYRLWLNVDNPLDPGRPMLIVG-------RGN 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 163 ILQVINIEMMSNYLLEPqlPWVERAVFNVNGESLEYGNPLIEPTV------------PSDDEVSYEQGSLRYPFTLTLYG 230
Cdd:COG4943   154 YVVVIDPAAFIDVLSPQ--PGISLALLATNGGHLFASSGNPDPALlsrllrgpsswfIQGDRLYASACSPQYPICVVAAA 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 231 PSPTRLALATLPSQLPLAL--LLSLLMGYIIWLATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHN 308
Cdd:COG4943   232 PLAGLLALWRQLLLLLLPLglLLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRD 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 309 ARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQ-LPDDSAFHIAINVAASHFRDRAILEDLQNLWWPAS-PVPQL 386
Cdd:COG4943   312 PDGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDlLAADPDFHISINLSASDLLSPRFLDDLERLLARTGvAPQQI 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 387 VVELTERDALPVVD-QSVIAQLHEIGVRLAIDDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQ 465
Cdd:COG4943   392 VLEITERGFIDPAKaRAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAK 471

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1750418682 466 RLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLEDFPAWLTRHQADARR 520
Cdd:COG4943   472 TLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAKPLPAEEFIAWLAAQRAPASA 526
PRK10551 PRK10551
cyclic di-GMP phosphodiesterase;
11-511 8.81e-91

cyclic di-GMP phosphodiesterase;


Pssm-ID: 182541 [Multi-domain]  Cd Length: 518  Bit Score: 287.27  E-value: 8.81e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  11 FRRKRLLIALSIATVVLILTLAFRYIEEKSRIEQQAMDFADKAIMRFDRMFSPLEVSASNTLGLVGAPCQDVRFPLIEKI 90
Cdd:PRK10551    8 SGRKILLTSIVAGVMIALLFSCLQFLLLWHKREVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQVNPELTSRA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  91 SSLQTVRAILLVENDMLYCSSIYGPRNIPFSQTYPDLAFNSQR-MTLATDEYLLKGSPILLLWTPKSLDNRSGILQVINI 169
Cdd:PRK10551   88 AFSLNVRAFLLVKDKKAFCSSATGEMNTPLSELIPAIDINKPVdMAILPGTPMMPNKPAIVIWYRNPLLKNSGVFATLNL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 170 EMMSnYLL----EPQLPWV-----ERAV--FN---VNGESLEyGNPLIEPTVPSddevsyeqgslrYPFTLTLYGPSPT- 234
Cdd:PRK10551  168 NLTP-YLLytsrQEDFDGIaliigNTALstFSsrlMNVNELP-DMPLRETTIPG------------YPLTIRLYADSWTa 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 235 ---RLALatlpsqlPLALLLSLLMGYIIWLATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQ 311
Cdd:PRK10551  234 ndiWYAL-------LLGLLSGILVGLLCYYLLSLRMRPGKEILTGIKRGQFYVEYQPVVDTQTLRVTGLEALLRWRHPTA 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 312 GWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQL----PDDSAFhiAINVAASHFRDRAILEDLQNlWWPASPVP--Q 385
Cdd:PRK10551  307 GEIPPDAFINYAEAQKLIVPLTQHLFELIARDAAELqkvlPVGAKL--GINISPAHLHSDSFKADVQR-LLASLPADhfQ 383

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 386 LVVELTERDalpVVDQSVIAQ----LHEIGVRLAIDDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVI 461
Cdd:PRK10551  384 IVLEITERD---MVQEEEATKlfawLHSQGIEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDAVL 460

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 1750418682 462 SLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLEDFPAWL 511
Cdd:PRK10551  461 TLAKRLNMLTVAEGVETPEQARWLRERGVNFLQGYWISRPLPLEDFVRWL 510
EAL cd01948
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 276-506 5.11e-89

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.


Pssm-ID: 238923 [Multi-domain]  Cd Length: 240  Bit Score: 272.88  E-value: 5.11e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 276 GITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQLPD-DSAFH 354
Cdd:cd01948     6 ALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAgGPDLR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 355 IAINVAASHFRDRAILEDLQNLWwPASPVP--QLVVELTERDALPVVDQS--VIAQLHEIGVRLAIDDFGTGHSSLSYLK 430
Cdd:cd01948    86 LSVNLSARQLRDPDFLDRLLELL-AETGLPprRLVLEITESALIDDLEEAlaTLRRLRALGVRIALDDFGTGYSSLSYLK 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1750418682 431 DLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLED 506
Cdd:cd01948   165 RLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAEE 240
EAL smart00052
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ...
 271-506 2.55e-86

Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.


Pssm-ID: 214491 [Multi-domain]  Cd Length: 242  Bit Score: 266.01  E-value: 2.55e-86
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  271 WQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQLPDD 350
Cdd:smart00052   2 RELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQAQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  351 S--AFHIAINVAASHFRDRAILEDLQNLWWPASPVP-QLVVELTERDALPVVDQSV--IAQLHEIGVRLAIDDFGTGHSS 425
Cdd:smart00052  82 GppPLLISINLSARQLISPDLVPRVLELLEETGLPPqRLELEITESVLLDDDESAVatLQRLRELGVRIALDDFGTGYSS 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  426 LSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLE 505
Cdd:smart00052 162 LSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPLD 241


                   .
gi 1750418682  506 D 506
Cdd:smart00052 242 D 242
EAL pfam00563
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 272-501 2.74e-71

EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.


Pssm-ID: 425752 [Multi-domain]  Cd Length: 235  Bit Score: 227.20  E-value: 2.74e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 272 QISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQLPDDS 351
Cdd:pfam00563   3 ALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQLGP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 352 AFHIAINVAASHFRDRAILEDLQNLWWPASPVPQ-LVVELTERDALPVVD--QSVIAQLHEIGVRLAIDDFGTGHSSLSY 428
Cdd:pfam00563  83 DIKLSINLSPASLADPGFLELLRALLKQAGPPPSrLVLEITESDLLARLEalREVLKRLRALGIRIALDDFGTGYSSLSY 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1750418682 429 LKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARP 501
Cdd:pfam00563 163 LLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
 
Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 10-520 2.67e-151

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 442.82  E-value: 2.67e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  10 QFRRKRL-----LIALSIATVVLILTLAFRYIEEKSRIEQQAMDFADKAIMRFDRMFSPLEVSASNTLGLVGAPCQDV-R 83
Cdd:COG4943     2 RMRRRRLlslatLLALLAALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSALDELNALPGDPCSPAhL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  84 FPLIEKISSLQTVRAILLVENDMLYCSSIyGPRNIPFSQTYPD-LAFNSQRMTLATDEYLLKGSPILLLWtpksldnRSG 162
Cdd:COG4943    82 AALRRLVFSSRYVRDIGYVRDGRLLCSSL-GKLSKPVPLPPPDyVTADGYRLWLNVDNPLDPGRPMLIVG-------RGN 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 163 ILQVINIEMMSNYLLEPqlPWVERAVFNVNGESLEYGNPLIEPTV------------PSDDEVSYEQGSLRYPFTLTLYG 230
Cdd:COG4943   154 YVVVIDPAAFIDVLSPQ--PGISLALLATNGGHLFASSGNPDPALlsrllrgpsswfIQGDRLYASACSPQYPICVVAAA 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 231 PSPTRLALATLPSQLPLAL--LLSLLMGYIIWLATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHN 308
Cdd:COG4943   232 PLAGLLALWRQLLLLLLPLglLLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRD 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 309 ARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQ-LPDDSAFHIAINVAASHFRDRAILEDLQNLWWPAS-PVPQL 386
Cdd:COG4943   312 PDGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDlLAADPDFHISINLSASDLLSPRFLDDLERLLARTGvAPQQI 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 387 VVELTERDALPVVD-QSVIAQLHEIGVRLAIDDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQ 465
Cdd:COG4943   392 VLEITERGFIDPAKaRAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAK 471

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1750418682 466 RLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLEDFPAWLTRHQADARR 520
Cdd:COG4943   472 TLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAKPLPAEEFIAWLAAQRAPASA 526
PRK10551 PRK10551
cyclic di-GMP phosphodiesterase;
11-511 8.81e-91

cyclic di-GMP phosphodiesterase;


Pssm-ID: 182541 [Multi-domain]  Cd Length: 518  Bit Score: 287.27  E-value: 8.81e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  11 FRRKRLLIALSIATVVLILTLAFRYIEEKSRIEQQAMDFADKAIMRFDRMFSPLEVSASNTLGLVGAPCQDVRFPLIEKI 90
Cdd:PRK10551    8 SGRKILLTSIVAGVMIALLFSCLQFLLLWHKREVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQVNPELTSRA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  91 SSLQTVRAILLVENDMLYCSSIYGPRNIPFSQTYPDLAFNSQR-MTLATDEYLLKGSPILLLWTPKSLDNRSGILQVINI 169
Cdd:PRK10551   88 AFSLNVRAFLLVKDKKAFCSSATGEMNTPLSELIPAIDINKPVdMAILPGTPMMPNKPAIVIWYRNPLLKNSGVFATLNL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 170 EMMSnYLL----EPQLPWV-----ERAV--FN---VNGESLEyGNPLIEPTVPSddevsyeqgslrYPFTLTLYGPSPT- 234
Cdd:PRK10551  168 NLTP-YLLytsrQEDFDGIaliigNTALstFSsrlMNVNELP-DMPLRETTIPG------------YPLTIRLYADSWTa 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 235 ---RLALatlpsqlPLALLLSLLMGYIIWLATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQ 311
Cdd:PRK10551  234 ndiWYAL-------LLGLLSGILVGLLCYYLLSLRMRPGKEILTGIKRGQFYVEYQPVVDTQTLRVTGLEALLRWRHPTA 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 312 GWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQL----PDDSAFhiAINVAASHFRDRAILEDLQNlWWPASPVP--Q 385
Cdd:PRK10551  307 GEIPPDAFINYAEAQKLIVPLTQHLFELIARDAAELqkvlPVGAKL--GINISPAHLHSDSFKADVQR-LLASLPADhfQ 383

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 386 LVVELTERDalpVVDQSVIAQ----LHEIGVRLAIDDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVI 461
Cdd:PRK10551  384 IVLEITERD---MVQEEEATKlfawLHSQGIEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDAVL 460

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 1750418682 462 SLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLEDFPAWL 511
Cdd:PRK10551  461 TLAKRLNMLTVAEGVETPEQARWLRERGVNFLQGYWISRPLPLEDFVRWL 510
EAL cd01948
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 276-506 5.11e-89

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.


Pssm-ID: 238923 [Multi-domain]  Cd Length: 240  Bit Score: 272.88  E-value: 5.11e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 276 GITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQLPD-DSAFH 354
Cdd:cd01948     6 ALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAgGPDLR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 355 IAINVAASHFRDRAILEDLQNLWwPASPVP--QLVVELTERDALPVVDQS--VIAQLHEIGVRLAIDDFGTGHSSLSYLK 430
Cdd:cd01948    86 LSVNLSARQLRDPDFLDRLLELL-AETGLPprRLVLEITESALIDDLEEAlaTLRRLRALGVRIALDDFGTGYSSLSYLK 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1750418682 431 DLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLED 506
Cdd:cd01948   165 RLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAEE 240
EAL smart00052
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ...
 271-506 2.55e-86

Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.


Pssm-ID: 214491 [Multi-domain]  Cd Length: 242  Bit Score: 266.01  E-value: 2.55e-86
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  271 WQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQLPDD 350
Cdd:smart00052   2 RELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQAQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  351 S--AFHIAINVAASHFRDRAILEDLQNLWWPASPVP-QLVVELTERDALPVVDQSV--IAQLHEIGVRLAIDDFGTGHSS 425
Cdd:smart00052  82 GppPLLISINLSARQLISPDLVPRVLELLEETGLPPqRLELEITESVLLDDDESAVatLQRLRELGVRIALDDFGTGYSS 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  426 LSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLE 505
Cdd:smart00052 162 LSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPLD 241


                   .
gi 1750418682  506 D 506
Cdd:smart00052 242 D 242
COG5001 COG5001
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ...
 262-516 1.18e-84

Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];


Pssm-ID: 444025 [Multi-domain]  Cd Length: 678  Bit Score: 275.50  E-value: 1.18e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 262 ATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVV 341
Cdd:COG5001   419 RARERLELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRWQHPERGLVSPAEFIPLAEETGLIVPLGEWVLREAC 498

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 342 RQLPQLPDD--SAFHIAINVAASHFRDRAILEDLQNLWWpASPVP--QLVVELTERDALPVVDQ--SVIAQLHEIGVRLA 415
Cdd:COG5001   499 RQLAAWQDAglPDLRVAVNLSARQLRDPDLVDRVRRALA-ETGLPpsRLELEITESALLEDPEEalETLRALRALGVRIA 577

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 416 IDDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQG 495
Cdd:COG5001   578 LDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVETEEQLEFLRELGCDYAQG 657

                         250       260
                  ....*....|....*....|.
gi 1750418682 496 YYFARPMPLEDFPAWLTRHQA 516
Cdd:COG5001   658 YLFSRPLPAEELEALLRARAA 678
EAL COG2200
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ...
 262-511 2.51e-82

EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms];


Pssm-ID: 441802 [Multi-domain]  Cd Length: 576  Bit Score: 267.04  E-value: 2.51e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 262 ATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVV 341
Cdd:COG2200   322 RARRRLALESELREALEEGELRLYYQPIVDLRTGRVVGYEALLRWRHPDGGLISPAEFIPAAERSGLIVELDRWVLERAL 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 342 RQLPQLPDDSA-FHIAINVAASHFRDRAILEDLQNLWwPASPVP--QLVVELTERDALPVVDQ--SVIAQLHEIGVRLAI 416
Cdd:COG2200   402 RQLARWPERGLdLRLSVNLSARSLLDPDFLERLLELL-AEYGLPpeRLVLEITESALLEDLEAaiELLARLRALGVRIAL 480

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 417 DDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGY 496
Cdd:COG2200   481 DDFGTGYSSLSYLKRLPPDYLKIDRSFVRDIARDPRDQAIVRAIVALAHRLGLKVVAEGVETEEQLEALRELGCDYAQGY 560

                         250
                  ....*....|....*
gi 1750418682 497 YFARPMPLEDFPAWL 511
Cdd:COG2200   561 LFGRPLPLEELEALL 575
EAL pfam00563
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 272-501 2.74e-71

EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.


Pssm-ID: 425752 [Multi-domain]  Cd Length: 235  Bit Score: 227.20  E-value: 2.74e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 272 QISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQLPDDS 351
Cdd:pfam00563   3 ALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQLGP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 352 AFHIAINVAASHFRDRAILEDLQNLWWPASPVPQ-LVVELTERDALPVVD--QSVIAQLHEIGVRLAIDDFGTGHSSLSY 428
Cdd:pfam00563  83 DIKLSINLSPASLADPGFLELLRALLKQAGPPPSrLVLEITESDLLARLEalREVLKRLRALGIRIALDDFGTGYSSLSY 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1750418682 429 LKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARP 501
Cdd:pfam00563 163 LLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
PRK10060 PRK10060
cyclic di-GMP phosphodiesterase;
281-516 1.65e-51

cyclic di-GMP phosphodiesterase;


Pssm-ID: 236645 [Multi-domain]  Cd Length: 663  Bit Score: 186.04  E-value: 1.65e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 281 EFMVYCQPLINSkSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQLPDDS-AFHIAINV 359
Cdd:PRK10060  421 QLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVMLDVVRQVAKWRDKGiNLRVAVNV 499

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 360 AASHFRDRAILEDLQNLWWPASPVPQLV-VELTER-----DALPVvdqSVIAQLHEIGVRLAIDDFGTGHSSLSYLKDLQ 433
Cdd:PRK10060  500 SARQLADQTIFTALKQALQELNFEYCPIdVELTESclienEELAL---SVIQQFSQLGAQVHLDDFGTGYSSLSQLARFP 576

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 434 PDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLEDFPAWLTR 513
Cdd:PRK10060  577 IDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKEDAFLTKNGVNERQGFLFAKPMPAVAFERWYKR 656


                  ...
gi 1750418682 514 HQA 516
Cdd:PRK10060  657 YLK 659
PRK11359 PRK11359
cyclic-di-GMP phosphodiesterase; Provisional
 262-516 3.70e-45

cyclic-di-GMP phosphodiesterase; Provisional


Pssm-ID: 183097 [Multi-domain]  Cd Length: 799  Bit Score: 169.56  E-value: 3.70e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 262 ATANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVV 341
Cdd:PRK11359  537 MVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEAC 616

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 342 RQLPQLpDDSAFHI---AINVAASHFRDRAI---LEDLQNLWwpASPVPQLVVELTERDALPVVDQ--SVIAQLHEIGVR 413
Cdd:PRK11359  617 RQLAEW-RSQNIHIpalSVNLSALHFRSNQLpnqVSDAMQAW--GIDGHQLTVEITESMMMEHDTEifKRIQILRDMGVG 693

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 414 LAIDDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDA-INATVtDMVISLAQRLNISLVAEGVETAEQADYLRERGVDH 492
Cdd:PRK11359  694 LSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKrILALL-EAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRV 772

                         250       260
                  ....*....|....*....|....
gi 1750418682 493 LQGYYFARPMPLEDFPAWLTRHQA 516
Cdd:PRK11359  773 IQGYFFSRPLPAEEIPGWMSSVLP 796
PRK13561 PRK13561
putative diguanylate cyclase; Provisional
 273-512 2.34e-42

putative diguanylate cyclase; Provisional


Pssm-ID: 184143 [Multi-domain]  Cd Length: 651  Bit Score: 160.26  E-value: 2.34e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 273 ISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLP------- 345
Cdd:PRK13561  405 ILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPEGLIDRIESCGLMVTVGHWVLEESCRLLAawqergi 484

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 346 QLPddsafhIAINVAASHFRDRAILEDLQNLWWPASPVP-QLVVELTERDALPVVDQSV--IAQLHEIGVRLAIDDFGTG 422
Cdd:PRK13561  485 MLP------LSVNLSALQLMHPNMVADMLELLTRYRIQPgTLILEVTESRRIDDPHAAVaiLRPLRNAGVRVALDDFGMG 558

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 423 HSSLSYL---KDLQPDVLKIDKIFTAAIGTDAinaTVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFA 499
Cdd:PRK13561  559 YAGLRQLqhmKSLPIDVLKIDKMFVDGLPEDD---SMVAAIIMLAQSLNLQVIAEGVETEAQRDWLLKAGVGIAQGFLFA 635

                         250
                  ....*....|....
gi 1750418682 500 RPMPLEDFPA-WLT 512
Cdd:PRK13561  636 RALPIEIFEErYLE 649
PRK11829 PRK11829
biofilm formation regulator HmsP; Provisional
 263-509 3.29e-36

biofilm formation regulator HmsP; Provisional


Pssm-ID: 183329 [Multi-domain]  Cd Length: 660  Bit Score: 142.77  E-value: 3.29e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 263 TANRMSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVR 342
Cdd:PRK11829  400 THKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEEEGMMVPLGNWVLEEACR 479

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 343 QLPQLPDDS-AFHIAINVAASHFRDRAILEDLQNLWWPASPVPQ-LVVELTERDALPVVDQS--VIAQLHEIGVRLAIDD 418
Cdd:PRK11829  480 ILADWKARGvSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQqLLLEITETAQIQDLDEAlrLLRELQGLGLLIALDD 559

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 419 FGTGHSSLSYL---KDLQPDVLKIDKIFTAAIGTDainATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQG 495
Cdd:PRK11829  560 FGIGYSSLRYLnhlKSLPIHMIKLDKSFVKNLPED---DAIARIISCVSDVLKVRVMAEGVETEEQRQWLLEHGIQCGQG 636

                         250
                  ....*....|....
gi 1750418682 496 YYFARPMPLEDFPA 509
Cdd:PRK11829  637 FLFSPPLPRAEFEA 650
PRK09776 PRK09776
putative diguanylate cyclase; Provisional
 267-507 1.85e-23

putative diguanylate cyclase; Provisional


Pssm-ID: 182070 [Multi-domain]  Cd Length: 1092  Bit Score: 104.75  E-value: 1.85e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  267 MSLSWQISYGITAREFMVYCQPLINSKSGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQLPQ 346
Cdd:PRK09776   840 LSLAEQWRMIKENQLMMLAHGVASPRIPEARNHWLISLRLWDPEGEIIDEGAFRPAAEDPALMHALDRRVIHEFFRQAAK 919

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  347 LPDDSAFHIAINVAASHFRDRAILEDLQNLWwPASPVP--QLVVELTErDAL---PVVDQSVIAQLHEIGVRLAIDDFGT 421
Cdd:PRK09776   920 AVASKGLSIALPLSVAGLSSPTLLPFLLEQL-ENSPLPprLLHLEITE-TALlnhAESASRLVQKLRLAGCRVVLSDFGR 997

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  422 GHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINATVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARP 501
Cdd:PRK09776   998 GLSSFNYLKAFMADYLKLDGELVANLHGNLMDEMLISIIQGHAQRLGMKTIAGPVELPLVLDTLSGIGVDLAYGYAIARP 1077


                   ....*.
gi 1750418682  502 MPLEDF 507
Cdd:PRK09776  1078 QPLDLL 1083
CSS-motif pfam12792
CSS motif domain associated with EAL; This family with its characteriztic highly conserved CSS ...
 43-237 4.16e-17

CSS motif domain associated with EAL; This family with its characteriztic highly conserved CSS sequence motif is found N-terminal to the EAL, pfam00563, domain in many cyclic diguanylate phosphodiesterases.


Pssm-ID: 463709  Cd Length: 209  Bit Score: 79.88  E-value: 4.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682  43 EQQAMDFADKAIMRFDRMFSPLEVSASNTLGLVGAPC-QDVRFPLIEKISSLQTVRAILLVENDMLYCSSIYGPRNIPFS 121
Cdd:pfam12792   2 QEQLDAFAERALRRLESVLDQADQALDRLLPLTGQPCsPAHLAELRRIVAFSPYVRDVGLVKNGRLYCSSLWGELDTPLP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 122 QTYPDL-AFNSQRMTLATDEYLLKGSPILLLWTPKSLD-NRSGILqvINIEMMSNYLLEPQlPWVERAVFNVNGES---- 195
Cdd:pfam12792  82 LLPPDLtTPPGVRLWLLRGTPLVPGRPALVLRRGGYGVvIDPGVF--IDVQYLPGLLAAVS-QPDGRLLALVVGDDallf 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1750418682 196 ---LEYGNPLIEPTVPSDDEVSYEQGSLRYPFTLTLYGPSPTRLA 237
Cdd:pfam12792 159 dgrLHSLAEPAPGTARSGGALYARARSTRYPLTVVVYAPRASLLA 203
YuxH COG3434
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction ...
 382-505 3.43e-14

c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction mechanisms];


Pssm-ID: 442660 [Multi-domain]  Cd Length: 407  Bit Score: 74.45  E-value: 3.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 382 PVPQLVVELTERDAlpvVDQSVIA---QLHEIGVRLAIDDFgtghsslSYLKDLQP-----DVLKIDkifTAAIGTDAIN 453
Cdd:COG3434    82 PPERVVLEILEDVE---PDEELLEalkELKEKGYRIALDDF-------VLDPEWDPllplaDIIKID---VLALDLEELA 148

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1750418682 454 AtvtdmVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLE 505
Cdd:COG3434   149 E-----LVARLKRYGIKLLAEKVETREEFELCKELGFDLFQGYFFSKPEILK 195
PRK11596 PRK11596
cyclic-di-GMP phosphodiesterase; Provisional
 287-509 4.97e-11

cyclic-di-GMP phosphodiesterase; Provisional


Pssm-ID: 183222 [Multi-domain]  Cd Length: 255  Bit Score: 63.10  E-value: 4.97e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 287 QPlINSKSGECDGIELLLR-WH-NARQGWITPDVF---IPLAERqnlikpltrfvLNEVVRQLPQLPDDSAFHIAINVAA 361
Cdd:PRK11596   35 QP-IYRTSGRLMAIELLTAvTHpSNPSQRLSPERYfaeITVSHR-----------LDVVKEQLDLLAQWADFFVRHGLLA 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 362 SHFRDRAILEDLQNLwwPA-----SPVPQLVVELTERDALPvvDQSVIAQLHEIGvRLAIDDFGTGHSSLSYLKDLQPDV 436
Cdd:PRK11596  103 SVNIDGPTLIALRQQ--PAilrliERLPWLRFELVEHIRLP--KDSPFASMCEFG-PLWLDDFGTGMANFSALSEVRYDY 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1750418682 437 LKIDK-IFTAAIGTDAINaTVTDMVISLAQRLNISLVAEGVETAEQADYLRERGVDHLQGYYFARPMPLEDFPA 509
Cdd:PRK11596  178 IKVAReLFIMLRQSEEGR-NLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFAAQGYFLSRPAPFETLET 250
PRK11059 PRK11059
regulatory protein CsrD; Provisional
 266-504 9.70e-09

regulatory protein CsrD; Provisional


Pssm-ID: 236833 [Multi-domain]  Cd Length: 640  Bit Score: 57.95  E-value: 9.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 266 RMSLSWQ--ISYGITAREFMVYCQPLINSKsGECDGIELLLRWHNARQGWITPDVFIPLAERQNLIKPLTRFVLNEVVRQ 343
Cdd:PRK11059  399 RGSVRWRtlLEQTLVRGGPRLYQQPAVTRD-GKVHHRELFCRIRDGQGELLSAELFMPMVQQLGLSEQYDRQVIERVLPL 477

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 344 LPQLPDDSafhIAINVAASHFRDRAILEDLQN--LWWPASPVPQLVVELTERDalpVVD-----QSVIAQLHEIGVRLAI 416
Cdd:PRK11059  478 LRYWPEEN---LSINLSVDSLLSRAFQRWLRDtlLQCPRSQRKRLIFELAEAD---VCQhisrlRPVLRMLRGLGCRLAV 551

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750418682 417 DDFGTGHSSLSYLKDLQPDVLKIDKIFTAAIGTDAINAT-VTDMVISLAqRLNISLVAEGVETAEQADYLRERGVDHLQG 495
Cdd:PRK11059  552 DQAGLTVVSTSYIKELNVELIKLHPSLVRNIHKRTENQLfVRSLVGACA-GTETQVFATGVESREEWQTLQELGVSGGQG 630


                  ....*....
gi 1750418682 496 YYFARPMPL 504
Cdd:PRK11059  631 DFFAESQPL 639
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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