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Conserved domains on  [gi|1705325861|ref|WP_142671008|]
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Cna B-type domain-containing protein, partial [Staphylococcus aureus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cna_B pfam05738
Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding ...
 63-130 4.10e-25

Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.


:

Pssm-ID: 461726 [Multi-domain]  Cd Length: 88  Bit Score: 90.77  E-value: 4.10e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705325861  63 ISGEKVWDDKDNQDGKRPEKVSVNLLANGEKV-ETVDVTSETNWKYEFKNLPKYDE-GKKIEYTVTEDHV 130
Cdd:pfam05738   1 VSVTKVWDDNNNQDGIRPESITVQLLANGQKVgVTKELTAANNWTYTFTDLPKYDEnGKEITYTVEEDAV 70
Cna_B super family cl47933
Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding ...
 2-55 1.92e-08

Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.


The actual alignment was detected with superfamily member pfam05738:

Pssm-ID: 461726 [Multi-domain]  Cd Length: 88  Bit Score: 48.40  E-value: 1.92e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1705325861   2 TLNESNNWTHTWAGLDEKAK-GQQVKYTVEElTKVKGYTTHVDNNDmgNLIVTNK 55
Cdd:pfam05738  37 ELTAANNWTYTFTDLPKYDEnGKEITYTVEE-DAVPGYTTTVDAKD--GFTITNT 88
 
Name Accession Description Interval E-value
Cna_B pfam05738
Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding ...
 63-130 4.10e-25

Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.


Pssm-ID: 461726 [Multi-domain]  Cd Length: 88  Bit Score: 90.77  E-value: 4.10e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705325861  63 ISGEKVWDDKDNQDGKRPEKVSVNLLANGEKV-ETVDVTSETNWKYEFKNLPKYDE-GKKIEYTVTEDHV 130
Cdd:pfam05738   1 VSVTKVWDDNNNQDGIRPESITVQLLANGQKVgVTKELTAANNWTYTFTDLPKYDEnGKEITYTVEEDAV 70
CollagenBindB cd00222
Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates ...
 61-130 6.00e-24

Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates bacterial adherence to collagen; the primary sequence has a non-repetitive, collagen-binding A region, followed by instances of this B region repetitive unit. The B region has one to four 23 kDa repeat units (B1-B4), which have been suggested to serve as 'stalks' that project the A region from the bacterial surface and thus facilitate bacterial adherence to collagen. Each B repeat unit has two highly similar domains (D1 and D2) placed side-by-side; both D1 and D2 are included in this model. They exhibit a unique inverse IgG-like domain fold.


Pssm-ID: 212461 [Multi-domain]  Cd Length: 92  Bit Score: 88.12  E-value: 6.00e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1705325861  61 TSISGEKVWDDKDNQDGKRPEKVSVNLLANGEK-VETVDVTSETNWKYEFKNLPKYDE-GKKIEYTVTEDHV 130
Cdd:cd00222     1 TDITVTKTWDDDDNQDGKRPESITVQLLANGKEtGDTVTLTASNDWTYTFTNLPKYDEnGKEITYTVKEVPV 72
Cna_B pfam05738
Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding ...
 2-55 1.92e-08

Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.


Pssm-ID: 461726 [Multi-domain]  Cd Length: 88  Bit Score: 48.40  E-value: 1.92e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1705325861   2 TLNESNNWTHTWAGLDEKAK-GQQVKYTVEElTKVKGYTTHVDNNDmgNLIVTNK 55
Cdd:pfam05738  37 ELTAANNWTYTFTDLPKYDEnGKEITYTVEE-DAVPGYTTTVDAKD--GFTITNT 88
CollagenBindB cd00222
Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates ...
 1-56 6.90e-08

Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates bacterial adherence to collagen; the primary sequence has a non-repetitive, collagen-binding A region, followed by instances of this B region repetitive unit. The B region has one to four 23 kDa repeat units (B1-B4), which have been suggested to serve as 'stalks' that project the A region from the bacterial surface and thus facilitate bacterial adherence to collagen. Each B repeat unit has two highly similar domains (D1 and D2) placed side-by-side; both D1 and D2 are included in this model. They exhibit a unique inverse IgG-like domain fold.


Pssm-ID: 212461 [Multi-domain]  Cd Length: 92  Bit Score: 46.90  E-value: 6.90e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1705325861   1 ATLNESNNWTHTWAGLDE-KAKGQQVKYTVEElTKVKGYTTHVDNNDMGNlIVTNKY 56
Cdd:cd00222    38 VTLTASNDWTYTFTNLPKyDENGKEITYTVKE-VPVPGYTTTVTGDDGGF-TITNTH 92
 
Name Accession Description Interval E-value
Cna_B pfam05738
Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding ...
 63-130 4.10e-25

Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.


Pssm-ID: 461726 [Multi-domain]  Cd Length: 88  Bit Score: 90.77  E-value: 4.10e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705325861  63 ISGEKVWDDKDNQDGKRPEKVSVNLLANGEKV-ETVDVTSETNWKYEFKNLPKYDE-GKKIEYTVTEDHV 130
Cdd:pfam05738   1 VSVTKVWDDNNNQDGIRPESITVQLLANGQKVgVTKELTAANNWTYTFTDLPKYDEnGKEITYTVEEDAV 70
CollagenBindB cd00222
Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates ...
 61-130 6.00e-24

Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates bacterial adherence to collagen; the primary sequence has a non-repetitive, collagen-binding A region, followed by instances of this B region repetitive unit. The B region has one to four 23 kDa repeat units (B1-B4), which have been suggested to serve as 'stalks' that project the A region from the bacterial surface and thus facilitate bacterial adherence to collagen. Each B repeat unit has two highly similar domains (D1 and D2) placed side-by-side; both D1 and D2 are included in this model. They exhibit a unique inverse IgG-like domain fold.


Pssm-ID: 212461 [Multi-domain]  Cd Length: 92  Bit Score: 88.12  E-value: 6.00e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1705325861  61 TSISGEKVWDDKDNQDGKRPEKVSVNLLANGEK-VETVDVTSETNWKYEFKNLPKYDE-GKKIEYTVTEDHV 130
Cdd:cd00222     1 TDITVTKTWDDDDNQDGKRPESITVQLLANGKEtGDTVTLTASNDWTYTFTNLPKYDEnGKEITYTVKEVPV 72
Cna_B pfam05738
Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding ...
 2-55 1.92e-08

Cna protein B-type domain; This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.


Pssm-ID: 461726 [Multi-domain]  Cd Length: 88  Bit Score: 48.40  E-value: 1.92e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1705325861   2 TLNESNNWTHTWAGLDEKAK-GQQVKYTVEElTKVKGYTTHVDNNDmgNLIVTNK 55
Cdd:pfam05738  37 ELTAANNWTYTFTDLPKYDEnGKEITYTVEE-DAVPGYTTTVDAKD--GFTITNT 88
CollagenBindB cd00222
Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates ...
 1-56 6.90e-08

Repeat unit of collagen-binding protein domain B; The collagen-binding protein mediates bacterial adherence to collagen; the primary sequence has a non-repetitive, collagen-binding A region, followed by instances of this B region repetitive unit. The B region has one to four 23 kDa repeat units (B1-B4), which have been suggested to serve as 'stalks' that project the A region from the bacterial surface and thus facilitate bacterial adherence to collagen. Each B repeat unit has two highly similar domains (D1 and D2) placed side-by-side; both D1 and D2 are included in this model. They exhibit a unique inverse IgG-like domain fold.


Pssm-ID: 212461 [Multi-domain]  Cd Length: 92  Bit Score: 46.90  E-value: 6.90e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1705325861   1 ATLNESNNWTHTWAGLDE-KAKGQQVKYTVEElTKVKGYTTHVDNNDMGNlIVTNKY 56
Cdd:cd00222    38 VTLTASNDWTYTFTNLPKyDENGKEITYTVKE-VPVPGYTTTVTGDDGGF-TITNTH 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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