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Conserved domains on  [gi|1676451497|ref|WP_138707302|]
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PspC-related protein choline-binding protein 1 [Streptococcus pseudopneumoniae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 1-1078 0e+00

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


:

Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 941.43  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497    1 MNRKDMKKQYSLRKIGKYVGSVVIGLSFAAVMNSTSTEVQAAqqppsaesfestddeiseegfttivtdlktkeavpfet 80
Cdd:NF033840     1 MEKFNTNKRYALRKLGKIFGSVIVGLTLFLGGILNTSFVHAA-------------------------------------- 42

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497   81 kyiaddtmelntkkevtpgklgakafknkvfykyetgektilkttpekviitepttqvikvgtkptvvtekieSSIKYIK 160
Cdd:NF033840    43 -------------------------------------------------------------------------STIRYIK 49

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  161 DPDRPIGSDVVTESEGEDGIKKITTTYVLDEKTGEVTVKNNTTTIEKKAQDIVYKVGAQDKIQETTINHKTIYEKDDNLE 240
Cdd:NF033840    50 DDTRPVGSNVLTESDGEDGIKKITTTYDLNEKTGEVTVKENTTTIEKKAQDIIYKVAAQDKIQEKTINHKTRFEKDENKE 129

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  241 VRKRKIKTPGEDGKIVTTTSYNVSPINGTPTPNTPIEKRtepktevitigtkptvrveeieseevkfekdlehqkgsnpe 320
Cdd:NF033840   130 RSENPVTIDGEDGKVVTTTTYDVSPETGTVTENVTIEKK----------------------------------------- 168

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  321 tipgengtkeitttykldtntgevselettekiltQPTPTVVKVPAKDKIEHKDIPIEAeyeadptlekgkkvddsnrqg 400
Cdd:NF033840   169 -----------------------------------EPTDTVIKVPAKSKVEREVLPTSV--------------------- 192

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  401 klgvrtitttyriengkavedtstekvttpmekkiikvgtkptvrvgdieskeVKFEKDLEHPRGSNPETIPGENGTKEI 480
Cdd:NF033840   193 -----------------------------------------------------IRFEKDETKDRSENPETIDGEDGYVTT 219

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  481 TTTYKLDTNTGEVSELETTEKilTQPTPTVVKVPAKDKVEKRIAEKStNIRFEKDETRDRNENPVTIdgedgyvttttty 560
Cdd:NF033840   220 TRTYDVDTETGEVTEKVTTDR--TEPTDTVIKVPAKSKVERRVLPTS-VIRFEKDETKDRSENPVTI------------- 283

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  561 dvnpetgkvsekvtvdrkeatdtvikvpakskvdrevlptsviryekdesrdrgasiemvdgedgyvtttttydvnpetg 640
Cdd:NF033840       --------------------------------------------------------------------------------

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  641 kvsetvtvdrkeatdtvikvpakskvdrevlptsviryekdesrdrgasiemvDGEDGYVTTTTTYDVNPETGKVSEKVT 720
Cdd:NF033840   284 -----------------------------------------------------DGEDGYVTTTRTYDVNPETGKVTEKVT 310

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  721 VDRKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDVDGKSGQVTESTLSQKEDSQT 800
Cdd:NF033840   311 VDRKEPTDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDVDGKSGQVTESTLSQKEDSQT 390

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  801 RVVKKGTKPQVLVQEIPIETEYLDDSTLDKGQEIEEAGEIGEITLTTIYTVDERDGTIEETTSRQITKEMVKRRIRRGTR 880
Cdd:NF033840   391 RVVKKGTKPQVLVQVIPIETEYLDDPTLDKGQEVEEAGEIGEITLTTIYTVDERDGTIEETTSRQITKEMVKRRIRRGTR 470

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  881 EPEKVVVPKKSSIPSYPVSVTSNQGTDSAVEPAKPVAATTGWKQENGMWYFYNTNGSMVTGWVqvngswyylnsngsmat 960
Cdd:NF033840   471 EPEKVVVPKKSSIPSYPVSVTSNQGTDAAVEPAKPVAPTTGWKQENGMWYFYNTDGSMATGWV----------------- 533

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  961 gwaQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGSMKA 1040
Cdd:NF033840   534 ---QVNGSWYYLNSNGSMATGWVQVNGSWYYLNSNGSMATGWVQVDGSWYYLNDNGSMETGWLQNNGSWYYLNSNGSMKA 610

                         1050      1060      1070
                   ....*....|....*....|....*....|....*...
gi 1676451497 1041 NQWFQVGSKWYYVNASGELAINTSIDGYRVNDNGEWVR 1078
Cdd:NF033840   611 NQWFQVGSKWYYVNASGELAVNTSIDGYRVNDNGEWVR 648
YabE super family cl34636
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 350-446 1.66e-08

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


The actual alignment was detected with superfamily member COG3583:

Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 57.57  E-value: 1.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  350 TEKILTQPTPTVVKVPAKDKIEHKDIPIEAEYEADPTLEKGK-KVDdsnRQGKLGVRTITTTYRIENGKAVE-DTSTEKV 427
Cdd:COG3583    135 DAPLTDGMTITVTRVTTKTVTEEEPIPFETVRKEDPSLPKGEtKVV---QEGVPGVKEVTYRVTYENGKEVSrEVVSEKV 211

                           90
                   ....*....|....*....
gi 1676451497  428 TTPMEKKIIKVGTKPTVRV 446
Cdd:COG3583    212 TKEPVDEVVAVGTKPRPAP 230
YabE super family cl34636
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 67-149 1.11e-06

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


The actual alignment was detected with superfamily member COG3583:

Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 51.79  E-value: 1.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497   67 VTDLKTKEAVPFETKYIADDTMELNTKKEVTPGKLGAKAFKNKVFYKyetGEKTILKTTPEKVIITEPTTQVIKVGTKPT 146
Cdd:COG3583    151 TKTVTEEEPIPFETVRKEDPSLPKGETKVVQEGVPGVKEVTYRVTYE---NGKEVSREVVSEKVTKEPVDEVVAVGTKPR 227


                   ...
gi 1676451497  147 VVT 149
Cdd:COG3583    228 PAP 230
YabE super family cl34636
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 269-371 3.35e-03

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


The actual alignment was detected with superfamily member COG3583:

Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 41.01  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  269 TPTPNTPIEKRTEpkTEVITIGTKPTVRVEEIESEEVKfEKDLEHQKGSNPETIPGENGTKEITTTYKLdTNTGEVSELE 348
Cdd:COG3583    131 SPALDAPLTDGMT--ITVTRVTTKTVTEEEPIPFETVR-KEDPSLPKGETKVVQEGVPGVKEVTYRVTY-ENGKEVSREV 206

                           90       100
                   ....*....|....*....|...
gi 1676451497  349 TTEKILTQPTPTVVKVPAKDKIE 371
Cdd:COG3583    207 VSEKVTKEPVDEVVAVGTKPRPA 229
 
Name Accession Description Interval E-value
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 1-1078 0e+00

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 941.43  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497    1 MNRKDMKKQYSLRKIGKYVGSVVIGLSFAAVMNSTSTEVQAAqqppsaesfestddeiseegfttivtdlktkeavpfet 80
Cdd:NF033840     1 MEKFNTNKRYALRKLGKIFGSVIVGLTLFLGGILNTSFVHAA-------------------------------------- 42

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497   81 kyiaddtmelntkkevtpgklgakafknkvfykyetgektilkttpekviitepttqvikvgtkptvvtekieSSIKYIK 160
Cdd:NF033840    43 -------------------------------------------------------------------------STIRYIK 49

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  161 DPDRPIGSDVVTESEGEDGIKKITTTYVLDEKTGEVTVKNNTTTIEKKAQDIVYKVGAQDKIQETTINHKTIYEKDDNLE 240
Cdd:NF033840    50 DDTRPVGSNVLTESDGEDGIKKITTTYDLNEKTGEVTVKENTTTIEKKAQDIIYKVAAQDKIQEKTINHKTRFEKDENKE 129

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  241 VRKRKIKTPGEDGKIVTTTSYNVSPINGTPTPNTPIEKRtepktevitigtkptvrveeieseevkfekdlehqkgsnpe 320
Cdd:NF033840   130 RSENPVTIDGEDGKVVTTTTYDVSPETGTVTENVTIEKK----------------------------------------- 168

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  321 tipgengtkeitttykldtntgevselettekiltQPTPTVVKVPAKDKIEHKDIPIEAeyeadptlekgkkvddsnrqg 400
Cdd:NF033840   169 -----------------------------------EPTDTVIKVPAKSKVEREVLPTSV--------------------- 192

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  401 klgvrtitttyriengkavedtstekvttpmekkiikvgtkptvrvgdieskeVKFEKDLEHPRGSNPETIPGENGTKEI 480
Cdd:NF033840   193 -----------------------------------------------------IRFEKDETKDRSENPETIDGEDGYVTT 219

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  481 TTTYKLDTNTGEVSELETTEKilTQPTPTVVKVPAKDKVEKRIAEKStNIRFEKDETRDRNENPVTIdgedgyvttttty 560
Cdd:NF033840   220 TRTYDVDTETGEVTEKVTTDR--TEPTDTVIKVPAKSKVERRVLPTS-VIRFEKDETKDRSENPVTI------------- 283

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  561 dvnpetgkvsekvtvdrkeatdtvikvpakskvdrevlptsviryekdesrdrgasiemvdgedgyvtttttydvnpetg 640
Cdd:NF033840       --------------------------------------------------------------------------------

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  641 kvsetvtvdrkeatdtvikvpakskvdrevlptsviryekdesrdrgasiemvDGEDGYVTTTTTYDVNPETGKVSEKVT 720
Cdd:NF033840   284 -----------------------------------------------------DGEDGYVTTTRTYDVNPETGKVTEKVT 310

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  721 VDRKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDVDGKSGQVTESTLSQKEDSQT 800
Cdd:NF033840   311 VDRKEPTDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDVDGKSGQVTESTLSQKEDSQT 390

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  801 RVVKKGTKPQVLVQEIPIETEYLDDSTLDKGQEIEEAGEIGEITLTTIYTVDERDGTIEETTSRQITKEMVKRRIRRGTR 880
Cdd:NF033840   391 RVVKKGTKPQVLVQVIPIETEYLDDPTLDKGQEVEEAGEIGEITLTTIYTVDERDGTIEETTSRQITKEMVKRRIRRGTR 470

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  881 EPEKVVVPKKSSIPSYPVSVTSNQGTDSAVEPAKPVAATTGWKQENGMWYFYNTNGSMVTGWVqvngswyylnsngsmat 960
Cdd:NF033840   471 EPEKVVVPKKSSIPSYPVSVTSNQGTDAAVEPAKPVAPTTGWKQENGMWYFYNTDGSMATGWV----------------- 533

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  961 gwaQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGSMKA 1040
Cdd:NF033840   534 ---QVNGSWYYLNSNGSMATGWVQVNGSWYYLNSNGSMATGWVQVDGSWYYLNDNGSMETGWLQNNGSWYYLNSNGSMKA 610

                         1050      1060      1070
                   ....*....|....*....|....*....|....*...
gi 1676451497 1041 NQWFQVGSKWYYVNASGELAINTSIDGYRVNDNGEWVR 1078
Cdd:NF033840   611 NQWFQVGSKWYYVNASGELAVNTSIDGYRVNDNGEWVR 648
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 909-1077 7.15e-94

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 313.39  E-value: 7.15e-94
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  909 AVEPAKPVAA-TTGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNG 987
Cdd:NF033930   431 APKPEQPAPApKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNG 510

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  988 SWYYLNSNGSMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGS------------------------------ 1037
Cdd:NF033930   511 SWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWLKYNGSWYYLNANGAmatgwlqyngswyylnangamatgwakvng 590

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497 1038 ------------------------------MKANQWFQVGSKWYYVNASGELAINTSIDGYRVNDNGEWV 1077
Cdd:NF033930   591 swyylnangsmatgwvkdgdtwyyleasgaMKASQWFKVSDKWYYVNGLGALAVNTTVDGYTVNANGEWV 660
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 912-1077 7.39e-93

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 311.56  E-value: 7.39e-93
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  912 PAKPVAATTGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNGSWYY 991
Cdd:NF033838   478 PAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYY 557

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  992 LNSNGSMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGS---------------------------------- 1037
Cdd:NF033838   558 LNANGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDmatgwlqyngswyylnangsmatgwvkdgdtwyy 637

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1676451497 1038 ------MKANQWFQVGSKWYYVNASGELAINTSIDGYRVNDNGEWV 1077
Cdd:NF033838   638 leasgaMKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWV 683
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
920-1078 1.32e-71

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 246.71  E-value: 1.32e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  920 TGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMA 999
Cdd:COG5263    326 TGWQKINGKWYYFDEDGAMATGWVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYYFDSSGAMA 405

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497 1000 TGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGSMKANqWFQVGSKWYYVNASGELAINT-SIDG--YRVNDNGEW 1076
Cdd:COG5263    406 TGWLKIDGKWYYFDSDGAMATGWQKIGGKWYYFDSNGAMATG-WVKVDGKWYYFDSDGAMATGWqTIDGktYYFDSNGAW 484


                   ..
gi 1676451497 1077 VR 1078
Cdd:COG5263    485 VG 486
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 939-980 3.13e-11

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 59.09  E-value: 3.13e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1676451497  939 VTGWVQVNGSWYYLNSNGSMATGW-AQVNGSWYYLN-SNGSMAT 980
Cdd:pfam19127    1 VTGWQTINGQTLYFDSDGKQVKGWvVTIDGKWYYFDaDSGEMVT 44
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 350-446 1.66e-08

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 57.57  E-value: 1.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  350 TEKILTQPTPTVVKVPAKDKIEHKDIPIEAEYEADPTLEKGK-KVDdsnRQGKLGVRTITTTYRIENGKAVE-DTSTEKV 427
Cdd:COG3583    135 DAPLTDGMTITVTRVTTKTVTEEEPIPFETVRKEDPSLPKGEtKVV---QEGVPGVKEVTYRVTYENGKEVSrEVVSEKV 211

                           90
                   ....*....|....*....
gi 1676451497  428 TTPMEKKIIKVGTKPTVRV 446
Cdd:COG3583    212 TKEPVDEVVAVGTKPRPAP 230
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 67-149 1.11e-06

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 51.79  E-value: 1.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497   67 VTDLKTKEAVPFETKYIADDTMELNTKKEVTPGKLGAKAFKNKVFYKyetGEKTILKTTPEKVIITEPTTQVIKVGTKPT 146
Cdd:COG3583    151 TKTVTEEEPIPFETVRKEDPSLPKGETKVVQEGVPGVKEVTYRVTYE---NGKEVSREVVSEKVTKEPVDEVVAVGTKPR 227


                   ...
gi 1676451497  147 VVT 149
Cdd:COG3583    228 PAP 230
G5 pfam07501
G5 domain; This domain is found in a wide range of extracellular proteins. It is found ...
 67-144 1.20e-05

G5 domain; This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.


Pssm-ID: 462185 [Multi-domain]  Cd Length: 75  Bit Score: 44.08  E-value: 1.20e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1676451497   67 VTDLKTKEAVPFETKYIADDTMELNTKKEVTPGKLGAKAFKNKVfyKYETGeKTILKTTPEKVIITEPTTQVIKVGTK 144
Cdd:pfam07501    1 EKTVTEEEEIPFETVTKEDPSLPKGEEKVVQEGKPGEKEVTYKV--TYVNG-KEVSREVVSEEVTKEPVDEVVAVGTK 75
G5 pfam07501
G5 domain; This domain is found in a wide range of extracellular proteins. It is found ...
 367-441 1.23e-05

G5 domain; This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.


Pssm-ID: 462185 [Multi-domain]  Cd Length: 75  Bit Score: 44.08  E-value: 1.23e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1676451497  367 KDKIEHKDIPIEAEYEADPTLEKGKKVDDsnRQGKLGVRTITTTYRIENGKAVE-DTSTEKVTTPMEKKIIKVGTK 441
Cdd:pfam07501    2 KTVTEEEEIPFETVTKEDPSLPKGEEKVV--QEGKPGEKEVTYKVTYVNGKEVSrEVVSEEVTKEPVDEVVAVGTK 75
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 950-1000 3.42e-05

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 42.51  E-value: 3.42e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1676451497  950 YYLNSNGSMATGWAQVNGSWYYLNSNGSMATG-WAQVNGSWYYLNSN-GSMAT 1000
Cdd:TIGR04035    1 YYFDADGKAVTGAQTIDGVTYYFDENGKQVKGdFVTNGGGTYYYDKDsGALVT 53
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 269-371 3.35e-03

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 41.01  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  269 TPTPNTPIEKRTEpkTEVITIGTKPTVRVEEIESEEVKfEKDLEHQKGSNPETIPGENGTKEITTTYKLdTNTGEVSELE 348
Cdd:COG3583    131 SPALDAPLTDGMT--ITVTRVTTKTVTEEEPIPFETVR-KEDPSLPKGETKVVQEGVPGVKEVTYRVTY-ENGKEVSREV 206

                           90       100
                   ....*....|....*....|...
gi 1676451497  349 TTEKILTQPTPTVVKVPAKDKIE 371
Cdd:COG3583    207 VSEKVTKEPVDEVVAVGTKPRPA 229
 
Name Accession Description Interval E-value
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 1-1078 0e+00

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 941.43  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497    1 MNRKDMKKQYSLRKIGKYVGSVVIGLSFAAVMNSTSTEVQAAqqppsaesfestddeiseegfttivtdlktkeavpfet 80
Cdd:NF033840     1 MEKFNTNKRYALRKLGKIFGSVIVGLTLFLGGILNTSFVHAA-------------------------------------- 42

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497   81 kyiaddtmelntkkevtpgklgakafknkvfykyetgektilkttpekviitepttqvikvgtkptvvtekieSSIKYIK 160
Cdd:NF033840    43 -------------------------------------------------------------------------STIRYIK 49

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  161 DPDRPIGSDVVTESEGEDGIKKITTTYVLDEKTGEVTVKNNTTTIEKKAQDIVYKVGAQDKIQETTINHKTIYEKDDNLE 240
Cdd:NF033840    50 DDTRPVGSNVLTESDGEDGIKKITTTYDLNEKTGEVTVKENTTTIEKKAQDIIYKVAAQDKIQEKTINHKTRFEKDENKE 129

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  241 VRKRKIKTPGEDGKIVTTTSYNVSPINGTPTPNTPIEKRtepktevitigtkptvrveeieseevkfekdlehqkgsnpe 320
Cdd:NF033840   130 RSENPVTIDGEDGKVVTTTTYDVSPETGTVTENVTIEKK----------------------------------------- 168

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  321 tipgengtkeitttykldtntgevselettekiltQPTPTVVKVPAKDKIEHKDIPIEAeyeadptlekgkkvddsnrqg 400
Cdd:NF033840   169 -----------------------------------EPTDTVIKVPAKSKVEREVLPTSV--------------------- 192

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  401 klgvrtitttyriengkavedtstekvttpmekkiikvgtkptvrvgdieskeVKFEKDLEHPRGSNPETIPGENGTKEI 480
Cdd:NF033840   193 -----------------------------------------------------IRFEKDETKDRSENPETIDGEDGYVTT 219

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  481 TTTYKLDTNTGEVSELETTEKilTQPTPTVVKVPAKDKVEKRIAEKStNIRFEKDETRDRNENPVTIdgedgyvttttty 560
Cdd:NF033840   220 TRTYDVDTETGEVTEKVTTDR--TEPTDTVIKVPAKSKVERRVLPTS-VIRFEKDETKDRSENPVTI------------- 283

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  561 dvnpetgkvsekvtvdrkeatdtvikvpakskvdrevlptsviryekdesrdrgasiemvdgedgyvtttttydvnpetg 640
Cdd:NF033840       --------------------------------------------------------------------------------

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  641 kvsetvtvdrkeatdtvikvpakskvdrevlptsviryekdesrdrgasiemvDGEDGYVTTTTTYDVNPETGKVSEKVT 720
Cdd:NF033840   284 -----------------------------------------------------DGEDGYVTTTRTYDVNPETGKVTEKVT 310

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  721 VDRKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDVDGKSGQVTESTLSQKEDSQT 800
Cdd:NF033840   311 VDRKEPTDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDVDGKSGQVTESTLSQKEDSQT 390

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  801 RVVKKGTKPQVLVQEIPIETEYLDDSTLDKGQEIEEAGEIGEITLTTIYTVDERDGTIEETTSRQITKEMVKRRIRRGTR 880
Cdd:NF033840   391 RVVKKGTKPQVLVQVIPIETEYLDDPTLDKGQEVEEAGEIGEITLTTIYTVDERDGTIEETTSRQITKEMVKRRIRRGTR 470

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  881 EPEKVVVPKKSSIPSYPVSVTSNQGTDSAVEPAKPVAATTGWKQENGMWYFYNTNGSMVTGWVqvngswyylnsngsmat 960
Cdd:NF033840   471 EPEKVVVPKKSSIPSYPVSVTSNQGTDAAVEPAKPVAPTTGWKQENGMWYFYNTDGSMATGWV----------------- 533

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  961 gwaQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGSMKA 1040
Cdd:NF033840   534 ---QVNGSWYYLNSNGSMATGWVQVNGSWYYLNSNGSMATGWVQVDGSWYYLNDNGSMETGWLQNNGSWYYLNSNGSMKA 610

                         1050      1060      1070
                   ....*....|....*....|....*....|....*...
gi 1676451497 1041 NQWFQVGSKWYYVNASGELAINTSIDGYRVNDNGEWVR 1078
Cdd:NF033840   611 NQWFQVGSKWYYVNASGELAVNTSIDGYRVNDNGEWVR 648
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 909-1077 7.15e-94

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 313.39  E-value: 7.15e-94
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  909 AVEPAKPVAA-TTGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNG 987
Cdd:NF033930   431 APKPEQPAPApKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNG 510

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  988 SWYYLNSNGSMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGS------------------------------ 1037
Cdd:NF033930   511 SWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWLKYNGSWYYLNANGAmatgwlqyngswyylnangamatgwakvng 590

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497 1038 ------------------------------MKANQWFQVGSKWYYVNASGELAINTSIDGYRVNDNGEWV 1077
Cdd:NF033930   591 swyylnangsmatgwvkdgdtwyyleasgaMKASQWFKVSDKWYYVNGLGALAVNTTVDGYTVNANGEWV 660
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 912-1077 7.39e-93

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 311.56  E-value: 7.39e-93
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  912 PAKPVAATTGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNGSWYY 991
Cdd:NF033838   478 PAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYY 557

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  992 LNSNGSMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGS---------------------------------- 1037
Cdd:NF033838   558 LNANGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDmatgwlqyngswyylnangsmatgwvkdgdtwyy 637

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1676451497 1038 ------MKANQWFQVGSKWYYVNASGELAINTSIDGYRVNDNGEWV 1077
Cdd:NF033838   638 leasgaMKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWV 683
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
920-1078 1.32e-71

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 246.71  E-value: 1.32e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  920 TGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMA 999
Cdd:COG5263    326 TGWQKINGKWYYFDEDGAMATGWVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYYFDSSGAMA 405

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497 1000 TGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGSMKANqWFQVGSKWYYVNASGELAINT-SIDG--YRVNDNGEW 1076
Cdd:COG5263    406 TGWLKIDGKWYYFDSDGAMATGWQKIGGKWYYFDSNGAMATG-WVKVDGKWYYFDSDGAMATGWqTIDGktYYFDSNGAW 484


                   ..
gi 1676451497 1077 VR 1078
Cdd:COG5263    485 VG 486
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
917-1078 4.70e-66

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 231.30  E-value: 4.70e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  917 AATTGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNG 996
Cdd:COG5263    303 KMVTGWQTINGKWYYFDSDGAMATGWQKINGKWYYFDEDGAMATGWVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNG 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  997 SMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGSMkANQWFQVGSKWYYVNASGELAIN-TSIDG--YRVNDN 1073
Cdd:COG5263    383 AMATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYYFDSDGAM-ATGWQKIGGKWYYFDSNGAMATGwVKVDGkwYYFDSD 461


                   ....*
gi 1676451497 1074 GEWVR 1078
Cdd:COG5263    462 GAMAT 466
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
917-1059 1.26e-62

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 221.67  E-value: 1.26e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  917 AATTGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNGSWYYLNSNG 996
Cdd:COG5263    343 AMATGWVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYYFDSDG 422

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1676451497  997 SMATGWEQVDGSWYYLNDNGSMEIGWLQNNGSWYYLNSNGSMKANqWFQVGSKWYYVNASGEL 1059
Cdd:COG5263    423 AMATGWQKIGGKWYYFDSNGAMATGWVKVDGKWYYFDSDGAMATG-WQTIDGKTYYFDSNGAW 484
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 939-980 3.13e-11

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 59.09  E-value: 3.13e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1676451497  939 VTGWVQVNGSWYYLNSNGSMATGW-AQVNGSWYYLN-SNGSMAT 980
Cdd:pfam19127    1 VTGWQTINGQTLYFDSDGKQVKGWvVTIDGKWYYFDaDSGEMVT 44
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 959-1000 1.36e-10

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 57.17  E-value: 1.36e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1676451497  959 ATGWAQVNGSWYYLNSNGSMATGW-AQVNGSWYYLN-SNGSMAT 1000
Cdd:pfam19127    1 VTGWQTINGQTLYFDSDGKQVKGWvVTIDGKWYYFDaDSGEMVT 44
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 979-1018 1.50e-10

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 57.17  E-value: 1.50e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1676451497  979 ATGWAQVNGSWYYLNSNGSMATGW-EQVDGSWYYLN-DNGSM 1018
Cdd:pfam19127    1 VTGWQTINGQTLYFDSDGKQVKGWvVTIDGKWYYFDaDSGEM 42
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 999-1043 2.99e-10

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 56.40  E-value: 2.99e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1676451497  999 ATGWEQVDGSWYYLNDNGSMEIGWL-QNNGSWYYLN-SNGSMKANQW 1043
Cdd:pfam19127    1 VTGWQTINGQTLYFDSDGKQVKGWVvTIDGKWYYFDaDSGEMVTNRF 47
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 920-960 1.85e-09

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 54.08  E-value: 1.85e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1676451497  920 TGWKQENGMWYFYNTNGSMVTGW-VQVNGSWYYLN-SNGSMAT 960
Cdd:pfam19127    2 TGWQTINGQTLYFDSDGKQVKGWvVTIDGKWYYFDaDSGEMVT 44
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 350-446 1.66e-08

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 57.57  E-value: 1.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  350 TEKILTQPTPTVVKVPAKDKIEHKDIPIEAEYEADPTLEKGK-KVDdsnRQGKLGVRTITTTYRIENGKAVE-DTSTEKV 427
Cdd:COG3583    135 DAPLTDGMTITVTRVTTKTVTEEEPIPFETVRKEDPSLPKGEtKVV---QEGVPGVKEVTYRVTYENGKEVSrEVVSEKV 211

                           90
                   ....*....|....*....
gi 1676451497  428 TTPMEKKIIKVGTKPTVRV 446
Cdd:COG3583    212 TKEPVDEVVAVGTKPRPAP 230
Choline_bind_1 pfam01473
Putative cell wall binding repeat; These repeats are characterized by conserved aromatic ...
 940-958 4.28e-07

Putative cell wall binding repeat; These repeats are characterized by conserved aromatic residues and glycines are found in multiple tandem copies in a number of proteins. The CW repeat is 20 amino acid residues long. The exact domain boundaries may not be correct. It has been suggested that these repeats in Swiss:P15057 might be responsible for the specific recognition of choline-containing cell walls. Similar but longer repeats are found in the glucosyltransferases and glucan-binding proteins of oral streptococci and shown to be involved in glucan binding as well as in the related dextransucrases of Leuconostoc mesenteroides. Repeats also occur in toxins of Clostridium difficile and other clostridia, though the ligands are not always known.


Pssm-ID: 366661 [Multi-domain]  Cd Length: 19  Bit Score: 47.00  E-value: 4.28e-07
                           10
                   ....*....|....*....
gi 1676451497  940 TGWVQVNGSWYYLNSNGSM 958
Cdd:pfam01473    1 TGWVKINGNWYYFDSNGVM 19
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 1021-1063 8.76e-07

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 46.38  E-value: 8.76e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1676451497 1021 GWLQNNGSWYYLNSNGSMKANQWFQVGSKWYYVNA-SGELAINT 1063
Cdd:pfam19127    3 GWQTINGQTLYFDSDGKQVKGWVVTIDGKWYYFDAdSGEMVTNR 46
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 67-149 1.11e-06

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 51.79  E-value: 1.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497   67 VTDLKTKEAVPFETKYIADDTMELNTKKEVTPGKLGAKAFKNKVFYKyetGEKTILKTTPEKVIITEPTTQVIKVGTKPT 146
Cdd:COG3583    151 TKTVTEEEPIPFETVRKEDPSLPKGETKVVQEGVPGVKEVTYRVTYE---NGKEVSREVVSEKVTKEPVDEVVAVGTKPR 227


                   ...
gi 1676451497  147 VVT 149
Cdd:COG3583    228 PAP 230
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 213-297 1.87e-06

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 51.41  E-value: 1.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  213 VYKVGAQDKIQETTINHKTIYEKDDNLEVRKRKIKTPGEDGKIVTTtsYNVSPINGTPTPNTPIEKR--TEPKTEVITIG 290
Cdd:COG3583    146 VTRVTTKTVTEEEPIPFETVRKEDPSLPKGETKVVQEGVPGVKEVT--YRVTYENGKEVSREVVSEKvtKEPVDEVVAVG 223


                   ....*..
gi 1676451497  291 TKPTVRV 297
Cdd:COG3583    224 TKPRPAP 230
Choline_bind_1 pfam01473
Putative cell wall binding repeat; These repeats are characterized by conserved aromatic ...
 960-978 3.27e-06

Putative cell wall binding repeat; These repeats are characterized by conserved aromatic residues and glycines are found in multiple tandem copies in a number of proteins. The CW repeat is 20 amino acid residues long. The exact domain boundaries may not be correct. It has been suggested that these repeats in Swiss:P15057 might be responsible for the specific recognition of choline-containing cell walls. Similar but longer repeats are found in the glucosyltransferases and glucan-binding proteins of oral streptococci and shown to be involved in glucan binding as well as in the related dextransucrases of Leuconostoc mesenteroides. Repeats also occur in toxins of Clostridium difficile and other clostridia, though the ligands are not always known.


Pssm-ID: 366661 [Multi-domain]  Cd Length: 19  Bit Score: 44.30  E-value: 3.27e-06
                           10
                   ....*....|....*....
gi 1676451497  960 TGWAQVNGSWYYLNSNGSM 978
Cdd:pfam01473    1 TGWVKINGNWYYFDSNGVM 19
Choline_bind_1 pfam01473
Putative cell wall binding repeat; These repeats are characterized by conserved aromatic ...
 980-998 3.27e-06

Putative cell wall binding repeat; These repeats are characterized by conserved aromatic residues and glycines are found in multiple tandem copies in a number of proteins. The CW repeat is 20 amino acid residues long. The exact domain boundaries may not be correct. It has been suggested that these repeats in Swiss:P15057 might be responsible for the specific recognition of choline-containing cell walls. Similar but longer repeats are found in the glucosyltransferases and glucan-binding proteins of oral streptococci and shown to be involved in glucan binding as well as in the related dextransucrases of Leuconostoc mesenteroides. Repeats also occur in toxins of Clostridium difficile and other clostridia, though the ligands are not always known.


Pssm-ID: 366661 [Multi-domain]  Cd Length: 19  Bit Score: 44.30  E-value: 3.27e-06
                           10
                   ....*....|....*....
gi 1676451497  980 TGWAQVNGSWYYLNSNGSM 998
Cdd:pfam01473    1 TGWVKINGNWYYFDSNGVM 19
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 795-989 4.85e-06

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 49.87  E-value: 4.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  795 KEDSQTRVVKKGTKPQVLVQEIPIETEYLDDSTLDKGQEIEEAGEIGEiTLTTIYTVDERDGTIEETT--SRQITKEMVK 872
Cdd:COG3583    139 TDGMTITVTRVTTKTVTEEEPIPFETVRKEDPSLPKGETKVVQEGVPG-VKEVTYRVTYENGKEVSREvvSEKVTKEPVD 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  873 RRIRRGTREPEKVVVPKKSSIPSYPVSVTSNQGTDSAVEPAKPVAATTGWKQENGMWYFYNTNGSMVTGWVQVNGSWYYL 952
Cdd:COG3583    218 EVVAVGTKPRPAPAPVPAGSGSGGGGSSTGSGGYGGLAASSATTAASGGGTGAPGGGGAARPTAGAVAGVVVVGGGGGGG 297

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1676451497  953 NSNGSMATGWAQVNGSWYYLNSNGSMATGWAQVNGSW 989
Cdd:COG3583    298 PGGGGGGGAAAGGGGGGGGGGAIDGAEGGSSAAAGGG 334
Choline_bind_1 pfam01473
Putative cell wall binding repeat; These repeats are characterized by conserved aromatic ...
 1000-1018 6.54e-06

Putative cell wall binding repeat; These repeats are characterized by conserved aromatic residues and glycines are found in multiple tandem copies in a number of proteins. The CW repeat is 20 amino acid residues long. The exact domain boundaries may not be correct. It has been suggested that these repeats in Swiss:P15057 might be responsible for the specific recognition of choline-containing cell walls. Similar but longer repeats are found in the glucosyltransferases and glucan-binding proteins of oral streptococci and shown to be involved in glucan binding as well as in the related dextransucrases of Leuconostoc mesenteroides. Repeats also occur in toxins of Clostridium difficile and other clostridia, though the ligands are not always known.


Pssm-ID: 366661 [Multi-domain]  Cd Length: 19  Bit Score: 43.53  E-value: 6.54e-06
                           10
                   ....*....|....*....
gi 1676451497 1000 TGWEQVDGSWYYLNDNGSM 1018
Cdd:pfam01473    1 TGWVKINGNWYYFDSNGVM 19
G5 pfam07501
G5 domain; This domain is found in a wide range of extracellular proteins. It is found ...
 67-144 1.20e-05

G5 domain; This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.


Pssm-ID: 462185 [Multi-domain]  Cd Length: 75  Bit Score: 44.08  E-value: 1.20e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1676451497   67 VTDLKTKEAVPFETKYIADDTMELNTKKEVTPGKLGAKAFKNKVfyKYETGeKTILKTTPEKVIITEPTTQVIKVGTK 144
Cdd:pfam07501    1 EKTVTEEEEIPFETVTKEDPSLPKGEEKVVQEGKPGEKEVTYKV--TYVNG-KEVSREVVSEEVTKEPVDEVVAVGTK 75
G5 pfam07501
G5 domain; This domain is found in a wide range of extracellular proteins. It is found ...
 367-441 1.23e-05

G5 domain; This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.


Pssm-ID: 462185 [Multi-domain]  Cd Length: 75  Bit Score: 44.08  E-value: 1.23e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1676451497  367 KDKIEHKDIPIEAEYEADPTLEKGKKVDDsnRQGKLGVRTITTTYRIENGKAVE-DTSTEKVTTPMEKKIIKVGTK 441
Cdd:pfam07501    2 KTVTEEEEIPFETVTKEDPSLPKGEEKVV--QEGKPGEKEVTYKVTYVNGKEVSrEVVSEEVTKEPVDEVVAVGTK 75
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 950-1000 3.42e-05

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 42.51  E-value: 3.42e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1676451497  950 YYLNSNGSMATGWAQVNGSWYYLNSNGSMATG-WAQVNGSWYYLNSN-GSMAT 1000
Cdd:TIGR04035    1 YYFDADGKAVTGAQTIDGVTYYFDENGKQVKGdFVTNGGGTYYYDKDsGALVT 53
Choline_bind_1 pfam01473
Putative cell wall binding repeat; These repeats are characterized by conserved aromatic ...
 1021-1038 4.67e-05

Putative cell wall binding repeat; These repeats are characterized by conserved aromatic residues and glycines are found in multiple tandem copies in a number of proteins. The CW repeat is 20 amino acid residues long. The exact domain boundaries may not be correct. It has been suggested that these repeats in Swiss:P15057 might be responsible for the specific recognition of choline-containing cell walls. Similar but longer repeats are found in the glucosyltransferases and glucan-binding proteins of oral streptococci and shown to be involved in glucan binding as well as in the related dextransucrases of Leuconostoc mesenteroides. Repeats also occur in toxins of Clostridium difficile and other clostridia, though the ligands are not always known.


Pssm-ID: 366661 [Multi-domain]  Cd Length: 19  Bit Score: 41.22  E-value: 4.67e-05
                           10
                   ....*....|....*...
gi 1676451497 1021 GWLQNNGSWYYLNSNGSM 1038
Cdd:pfam01473    2 GWVKINGNWYYFDSNGVM 19
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 930-980 6.05e-05

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 41.74  E-value: 6.05e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1676451497  930 YFYNTNGSMVTGWVQVNGSWYYLNSNGSMATG-WAQVNGSWYYLNSN-GSMAT 980
Cdd:TIGR04035    1 YYFDADGKAVTGAQTIDGVTYYFDENGKQVKGdFVTNGGGTYYYDKDsGALVT 53
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 970-1048 1.18e-04

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 40.97  E-value: 1.18e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1676451497  970 YYLNSNGSMATGWAQVNGSWYYLNSNGSmatgweQVDGSWyyLNDNGsmeigwlqnnGSWYYLNSNGSMKANQWFQVGS 1048
Cdd:TIGR04035    1 YYFDADGKAVTGAQTIDGVTYYFDENGK------QVKGDF--VTNGG----------GTYYYDKDSGALVTNRFVTIKD 61
RpoC COG0086
DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; DNA-directed RNA ...
 147-563 2.13e-04

DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; DNA-directed RNA polymerase, beta' subunit/160 kD subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 439856 [Multi-domain]  Cd Length: 1165  Bit Score: 45.54  E-value: 2.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  147 VVTEKIESSIKYIKDPDRPIGSDVVtESEGEDGIKKITTTYVLDEKTGEVTVKNNTTTIEKKAQDIVYKVGAQDKIQETT 226
Cdd:COG0086    774 IVTEEDCGTDRGITVTAIKEGGEVI-EPLKERILGRVAAEDVVDPGTGEVLVPAGTLIDEEVAEIIEEAGIDSVKVRSVL 852

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  227 INHKT-----IYEKDDNLEVRKRKIktpGEDGKIVTTTSynvspingTPTPNTPIEKRTepkteviTIGTKPTVRVEEIE 301
Cdd:COG0086    853 TCETRggvcaKCYGRDLARGHLVNI---GEAVGVIAAQS--------IGEPGTQLTMRT-------FHIGGAASRAAEES 914

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  302 SEEVKFEKDLEHqkgSNPETIPGENGTKEITTtykldTNTGEVSELETTEKILTQPTPTVVKVPAKDKIEHKDIPIEAEY 381
Cdd:COG0086    915 SIEAKAGGIVRL---NNLKVVVNEEGKGVVVS-----RNSELVIVDDGGRREEEYKVPYGGVLVVVGGGVVVGGGIVAEW 986

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  382 EaDPTLEKGKKVDDSNRQGKLGVRTITTTYRIEngkavEDTSTEKVTTPMEKKIIKVGTKPTVRVGDIESKEVKFEKDLE 461
Cdd:COG0086    987 D-PHTPPIIEEVGGGVVFDDIVEGGVIVEKTDE-----ETGGLSIVVEDDKARRGGGKLLIRALKLLDAVGLSLLLGGTD 1060

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  462 HPRGSNPETIPGENGTKEITTTYKLDTNTGEVSELETTEKILTQPTPTVVKVPAKDKVEKRIAEKSTNIRFEKDETRDRN 541
Cdd:COG0086   1061 AAAAGVIIGGLDVVLGDGVAIGVGAAIARIPGLSGGTRDGTGGLARVAAAAEAKEAKEIAAGAEIIGGVGFGKKTKKKRR 1140

                          410       420
                   ....*....|....*....|..
gi 1676451497  542 ENPVTIDGEDGYVTTTTTYDVN 563
Cdd:COG0086   1141 LVITEEDGSPIEEEVVKKKRIL 1162
G5 pfam07501
G5 domain; This domain is found in a wide range of extracellular proteins. It is found ...
 223-292 2.38e-04

G5 domain; This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.


Pssm-ID: 462185 [Multi-domain]  Cd Length: 75  Bit Score: 40.61  E-value: 2.38e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1676451497  223 QETTINHKTIYEKDDNLEVRKRKIKTPGEDGKIVTTtsYNVSPINGTPTPNTPIEKR--TEPKTEVITIGTK 292
Cdd:pfam07501    6 EEEEIPFETVTKEDPSLPKGEEKVVQEGKPGEKEVT--YKVTYVNGKEVSREVVSEEvtKEPVDEVVAVGTK 75
Choline_bind_1 pfam01473
Putative cell wall binding repeat; These repeats are characterized by conserved aromatic ...
 920-938 6.13e-04

Putative cell wall binding repeat; These repeats are characterized by conserved aromatic residues and glycines are found in multiple tandem copies in a number of proteins. The CW repeat is 20 amino acid residues long. The exact domain boundaries may not be correct. It has been suggested that these repeats in Swiss:P15057 might be responsible for the specific recognition of choline-containing cell walls. Similar but longer repeats are found in the glucosyltransferases and glucan-binding proteins of oral streptococci and shown to be involved in glucan binding as well as in the related dextransucrases of Leuconostoc mesenteroides. Repeats also occur in toxins of Clostridium difficile and other clostridia, though the ligands are not always known.


Pssm-ID: 366661 [Multi-domain]  Cd Length: 19  Bit Score: 37.75  E-value: 6.13e-04
                           10
                   ....*....|....*....
gi 1676451497  920 TGWKQENGMWYFYNTNGSM 938
Cdd:pfam01473    1 TGWVKINGNWYYFDSNGVM 19
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 424-520 1.40e-03

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 42.16  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  424 TEKVTTPMEKKIIKVGTKPTVRVGDIEsKEVKFEKDLEHPRGSNPETIPGENGTKEITTTYKLdTNTGEVSELETTEKIL 503
Cdd:COG3583    135 DAPLTDGMTITVTRVTTKTVTEEEPIP-FETVRKEDPSLPKGETKVVQEGVPGVKEVTYRVTY-ENGKEVSREVVSEKVT 212

                           90
                   ....*....|....*..
gi 1676451497  504 TQPTPTVVKVPAKDKVE 520
Cdd:COG3583    213 KEPVDEVVAVGTKPRPA 229
G5 pfam07501
G5 domain; This domain is found in a wide range of extracellular proteins. It is found ...
 736-808 1.84e-03

G5 domain; This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.


Pssm-ID: 462185 [Multi-domain]  Cd Length: 75  Bit Score: 37.92  E-value: 1.84e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1676451497  736 KSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNG-KTVTTITYDVDGKsgQVTESTLSQKEDSQ--TRVVKKGTK 808
Cdd:pfam07501    2 KTVTEEEEIPFETVTKEDPSLPKGEEKVVQEGKPGeKEVTYKVTYVNGK--EVSREVVSEEVTKEpvDEVVAVGTK 75
YabE COG3583
Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function ...
 269-371 3.35e-03

Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown];


Pssm-ID: 442802 [Multi-domain]  Cd Length: 335  Bit Score: 41.01  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676451497  269 TPTPNTPIEKRTEpkTEVITIGTKPTVRVEEIESEEVKfEKDLEHQKGSNPETIPGENGTKEITTTYKLdTNTGEVSELE 348
Cdd:COG3583    131 SPALDAPLTDGMT--ITVTRVTTKTVTEEEPIPFETVR-KEDPSLPKGETKVVQEGVPGVKEVTYRVTY-ENGKEVSREV 206

                           90       100
                   ....*....|....*....|...
gi 1676451497  349 TTEKILTQPTPTVVKVPAKDKIE 371
Cdd:COG3583    207 VSEKVTKEPVDEVVAVGTKPRPA 229
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 1010-1066 3.38e-03

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 36.73  E-value: 3.38e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1676451497 1010 YYLNDNGSMEIGWlQN-NGSWYYLNSNGSMKANQWFQVGSKWYYVNA-SGELAINTSID 1066
Cdd:TIGR04035    1 YYFDADGKAVTGA-QTiDGVTYYFDENGKQVKGDFVTNGGGTYYYDKdSGALVTNRFVT 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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