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Conserved domains on  [gi|1604899012|ref|WP_134688735|]
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IS66 family transposase, partial [Escherichia coli]

Protein Classification

IS66 family transposase( domain architecture ID 1750062)

IS66 family transposase insertion sequence element encodes a DDE transposase TnpC, and two accessory proteins, TnpA and TnpB.

PubMed:  20079432

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
transpos_IS66 NF033517
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
1-187 7.80e-79

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


:

Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 239.79  E-value: 7.80e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012   1 ACCRCDHIVQAPVPSKPIARSYAGAGLLAHIVTGKYADHLPLYRQSEIYRRQ-GVELSRATLGRWTGAVAELLEPLYDVL 79
Cdd:NF033517   65 ACRHCGTVVQAPAPARVIPKGQAGPRLLAHVAVLKYADHLPLYRQQQILARLfGIELSRGTLANWVGRAAELLEPLYDAL 144
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012  80 RQYVLMPGKVHADDIPVPVQEPGSGKtrTARLWVYVRDdrnagsqmPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYG 159
Cdd:NF033517  145 KEELLAAPVLHADETGVPVLEPGRGK--TGWLWVYASA--------PPAVLFDYAPSRGGEVPEALLEGFNGVLQSDGYA 214
                         170       180
                  ....*....|....*....|....*...
gi 1604899012 160 GYRALYesgRITEAACMAHARRKIHDVH 187
Cdd:NF033517  215 GYNKLA---AVTHAGCWAHLRRKFQEAA 239
 
Name Accession Description Interval E-value
transpos_IS66 NF033517
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
1-187 7.80e-79

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 239.79  E-value: 7.80e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012   1 ACCRCDHIVQAPVPSKPIARSYAGAGLLAHIVTGKYADHLPLYRQSEIYRRQ-GVELSRATLGRWTGAVAELLEPLYDVL 79
Cdd:NF033517   65 ACRHCGTVVQAPAPARVIPKGQAGPRLLAHVAVLKYADHLPLYRQQQILARLfGIELSRGTLANWVGRAAELLEPLYDAL 144
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012  80 RQYVLMPGKVHADDIPVPVQEPGSGKtrTARLWVYVRDdrnagsqmPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYG 159
Cdd:NF033517  145 KEELLAAPVLHADETGVPVLEPGRGK--TGWLWVYASA--------PPAVLFDYAPSRGGEVPEALLEGFNGVLQSDGYA 214
                         170       180
                  ....*....|....*....|....*...
gi 1604899012 160 GYRALYesgRITEAACMAHARRKIHDVH 187
Cdd:NF033517  215 GYNKLA---AVTHAGCWAHLRRKFQEAA 239
DDE_Tnp_IS66 pfam03050
Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. ...
20-187 6.82e-78

Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.


Pssm-ID: 427113 [Multi-domain]  Cd Length: 281  Bit Score: 234.07  E-value: 6.82e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012  20 RSYAGAGLLAHIVTGKYADHLPLYRQSEIYRRQGVELSRATLGRWTGAVAELLEPLYDVLRQYVLMPGKVHADDIPVPVQ 99
Cdd:pfam03050   1 KSLAGPSLLALILVLKYADHLPLYRQEDILARLGVELSRGTLANWVGRAAELLEPLVDALRAALLESPVIHADETPLRVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012 100 EPGSGKTRTARLWVYVRDDRNagsqmPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYGGYRALYEsGRITEAACMAHA 179
Cdd:pfam03050  81 KPGRGKGKKGWLWVYVTDDRP-----PPAVLFHYHPSRGGEHPQALLGGFRGVLQTDGYAGYNKLAR-GQVTHAGCWAHA 154

                  ....*...
gi 1604899012 180 RRKIHDVH 187
Cdd:pfam03050 155 RRKFFDAH 162
COG3436 COG3436
Transposase [Mobilome: prophages, transposons];
2-188 3.35e-59

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442662 [Multi-domain]  Cd Length: 416  Bit Score: 190.24  E-value: 3.35e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012   2 CCRCDHIVQAPVPSKPIARSYAGAGLLAHIVTGKYADHLPLYRQSEIYRRQGVELSRATLGRWTGAVAELLEPLYDVLRQ 81
Cdd:COG3436   124 YCDGTGLVYAPAPAKRLEKGLAGPGLLAHILVSKFVDHLPLYRQEEIFARLGVELSRSTLLNWVGRAAELLEPLLEGLDE 203
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012  82 YVLMPGKVHADDIPVPVQEPGSGKTRTARLWVYVRDDRNAGSQMPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYGGY 161
Cdd:COG3436   204 RLLAAPVLHADETPVQVLDEGKGKTVTASYWWVYRDGRPSRGPVVYDAYRSRRGARAGLVLDGGLGGGLGDDYADGYAAL 283
                         170       180
                  ....*....|....*....|....*..
gi 1604899012 162 RALYESGRITEAACMAHARRKIHDVHA 188
Cdd:COG3436   284 LRLAELGCAAAARRRRKAAAAALKKLA 310
 
Name Accession Description Interval E-value
transpos_IS66 NF033517
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
1-187 7.80e-79

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 239.79  E-value: 7.80e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012   1 ACCRCDHIVQAPVPSKPIARSYAGAGLLAHIVTGKYADHLPLYRQSEIYRRQ-GVELSRATLGRWTGAVAELLEPLYDVL 79
Cdd:NF033517   65 ACRHCGTVVQAPAPARVIPKGQAGPRLLAHVAVLKYADHLPLYRQQQILARLfGIELSRGTLANWVGRAAELLEPLYDAL 144
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012  80 RQYVLMPGKVHADDIPVPVQEPGSGKtrTARLWVYVRDdrnagsqmPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYG 159
Cdd:NF033517  145 KEELLAAPVLHADETGVPVLEPGRGK--TGWLWVYASA--------PPAVLFDYAPSRGGEVPEALLEGFNGVLQSDGYA 214
                         170       180
                  ....*....|....*....|....*...
gi 1604899012 160 GYRALYesgRITEAACMAHARRKIHDVH 187
Cdd:NF033517  215 GYNKLA---AVTHAGCWAHLRRKFQEAA 239
DDE_Tnp_IS66 pfam03050
Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. ...
20-187 6.82e-78

Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.


Pssm-ID: 427113 [Multi-domain]  Cd Length: 281  Bit Score: 234.07  E-value: 6.82e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012  20 RSYAGAGLLAHIVTGKYADHLPLYRQSEIYRRQGVELSRATLGRWTGAVAELLEPLYDVLRQYVLMPGKVHADDIPVPVQ 99
Cdd:pfam03050   1 KSLAGPSLLALILVLKYADHLPLYRQEDILARLGVELSRGTLANWVGRAAELLEPLVDALRAALLESPVIHADETPLRVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012 100 EPGSGKTRTARLWVYVRDDRNagsqmPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYGGYRALYEsGRITEAACMAHA 179
Cdd:pfam03050  81 KPGRGKGKKGWLWVYVTDDRP-----PPAVLFHYHPSRGGEHPQALLGGFRGVLQTDGYAGYNKLAR-GQVTHAGCWAHA 154

                  ....*...
gi 1604899012 180 RRKIHDVH 187
Cdd:pfam03050 155 RRKFFDAH 162
COG3436 COG3436
Transposase [Mobilome: prophages, transposons];
2-188 3.35e-59

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442662 [Multi-domain]  Cd Length: 416  Bit Score: 190.24  E-value: 3.35e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012   2 CCRCDHIVQAPVPSKPIARSYAGAGLLAHIVTGKYADHLPLYRQSEIYRRQGVELSRATLGRWTGAVAELLEPLYDVLRQ 81
Cdd:COG3436   124 YCDGTGLVYAPAPAKRLEKGLAGPGLLAHILVSKFVDHLPLYRQEEIFARLGVELSRSTLLNWVGRAAELLEPLLEGLDE 203
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604899012  82 YVLMPGKVHADDIPVPVQEPGSGKTRTARLWVYVRDDRNAGSQMPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYGGY 161
Cdd:COG3436   204 RLLAAPVLHADETPVQVLDEGKGKTVTASYWWVYRDGRPSRGPVVYDAYRSRRGARAGLVLDGGLGGGLGDDYADGYAAL 283
                         170       180
                  ....*....|....*....|....*..
gi 1604899012 162 RALYESGRITEAACMAHARRKIHDVHA 188
Cdd:COG3436   284 LRLAELGCAAAARRRRKAAAAALKKLA 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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