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Conserved domains on  [gi|1592456265|ref|WP_132355929|]
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amino acid permease [Photorhabdus khanii]

Protein Classification

amino acid permease( domain architecture ID 11438095)

amino acid permease facilitates the transport of amino acids; similar to Mycobacterium tuberculosis L-asparagine permease

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
2-447 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


:

Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 640.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYAS 81
Cdd:COG1113     7 ASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFSDYAR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  82 HYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAI 161
Cdd:COG1113    87 EYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIKVVAI 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 162 IAMIIGGMAIMVYGFGQETDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:COG1113   167 VAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKAINSV 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAP 321
Cdd:COG1113   247 IWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAERGDAP 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 322 KSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLKFPVP 401
Cdd:COG1113   327 KFFGKLSKRGVPVRAILLSAVVLLIGVVLNYLLPEKAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGAAALKFKMP 406
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1592456265 402 MWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFL 447
Cdd:COG1113   407 GFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFL 452
 
Name Accession Description Interval E-value
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
2-447 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 640.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYAS 81
Cdd:COG1113     7 ASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFSDYAR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  82 HYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAI 161
Cdd:COG1113    87 EYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIKVVAI 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 162 IAMIIGGMAIMVYGFGQETDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:COG1113   167 VAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKAINSV 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAP 321
Cdd:COG1113   247 IWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAERGDAP 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 322 KSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLKFPVP 401
Cdd:COG1113   327 KFFGKLSKRGVPVRAILLSAVVLLIGVVLNYLLPEKAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGAAALKFKMP 406
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1592456265 402 MWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFL 447
Cdd:COG1113   407 GFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFL 452
proY PRK10580
putative proline-specific permease; Provisional
2-447 0e+00

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 553.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYAS 81
Cdd:PRK10580    1 MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  82 HYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAI 161
Cdd:PRK10580   81 ENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 162 IAMIIGGMAIMVYGFGQeTDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:PRK10580  161 IIMIVAGIGIIIWGIGN-GGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSV 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAP 321
Cdd:PRK10580  240 PMRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAP 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 322 KSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLKFPVP 401
Cdd:PRK10580  320 KIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVP 399
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1592456265 402 MWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFL 447
Cdd:PRK10580  400 GGVATTIGGLIFLVFIIGLIGYHPDTRISLYVGFAWIVLLLIGWMF 445
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
7-432 5.27e-94

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 291.39  E-value: 5.27e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   7 QLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGP 86
Cdd:TIGR01773   9 KLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAIGR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  87 LAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMII 166
Cdd:TIGR01773  89 WAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAFII 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 167 GGmAIMVYGFGQETDhVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRIL 246
Cdd:TIGR01773 169 LG-AVAIFGFAPGSE-VSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWRII 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 247 LFYVLTLFILMCIYPWNQIG-QEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSFT 325
Cdd:TIGR01773 247 VFYLGSIFIVVALLPWNSPNlLEVGSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPRVFM 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 326 KLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMsKEEVKTLKFPVPMWPI 405
Cdd:TIGR01773 327 KLNKKGVPVQAVLASTFFSFLTVVVNYFAPDKVFLFLVNSSGAIALLVYLVIAVSQLRMRKKL-KANGEAIKIRMWLYPW 405
                         410       420
                  ....*....|....*....|....*..
gi 1592456265 406 APILTIIFMVFIIILLGYFEKTRIALI 432
Cdd:TIGR01773 406 LTWLVIIFICGILVSMLFIPSMRDEVL 432
AA_permease pfam00324
Amino acid permease;
16-456 1.04e-90

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 283.44  E-value: 1.04e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  16 HIRFMALGSAIGTGLFYGSAAAIQQAGPA-VLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGPLAGFLTGW 94
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAgALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  95 NYIFEMLIVCLADVTAFGFYMKLWFPHVE---QWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMIIGGMai 171
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWELVPDipyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGI-- 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 172 mVYGFGQETDHVTGISSLWEYGG---FMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLF 248
Cdd:pfam00324 159 -ILLSGGNPNDGAIFRYLGDNGGknnFPPGFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIF 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 249 YVLTLFILMCIYPWNQIG------QEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPK 322
Cdd:pfam00324 238 YILSLLAIGLLVPWNDPGllndsaSAASPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPK 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 323 SFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLKFPVPM 402
Cdd:pfam00324 318 FLKKVDKRGVPLRAILVSMVISLLALLLASLNPAIVFNFLLAISGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKA 397
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1592456265 403 W--PIAPILTIIFMVFIIILLGYFEKTR-------------IALIVGIAWVALLSITYFLGIKKNTSQN 456
Cdd:pfam00324 398 PlgPLGVILGLAAIIIILIIQFLYAFLPvpggpknwgagsfAAAYLIVLLFLIILIGVKLHVKNWKPQL 466
 
Name Accession Description Interval E-value
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
2-447 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 640.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYAS 81
Cdd:COG1113     7 ASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFSDYAR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  82 HYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAI 161
Cdd:COG1113    87 EYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIKVVAI 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 162 IAMIIGGMAIMVYGFGQETDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:COG1113   167 VAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKAINSV 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAP 321
Cdd:COG1113   247 IWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAERGDAP 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 322 KSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLKFPVP 401
Cdd:COG1113   327 KFFGKLSKRGVPVRAILLSAVVLLIGVVLNYLLPEKAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGAAALKFKMP 406
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1592456265 402 MWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFL 447
Cdd:COG1113   407 GFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFL 452
proY PRK10580
putative proline-specific permease; Provisional
2-447 0e+00

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 553.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYAS 81
Cdd:PRK10580    1 MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  82 HYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAI 161
Cdd:PRK10580   81 ENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 162 IAMIIGGMAIMVYGFGQeTDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:PRK10580  161 IIMIVAGIGIIIWGIGN-GGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSV 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAP 321
Cdd:PRK10580  240 PMRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAP 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 322 KSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLKFPVP 401
Cdd:PRK10580  320 KIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVP 399
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1592456265 402 MWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFL 447
Cdd:PRK10580  400 GGVATTIGGLIFLVFIIGLIGYHPDTRISLYVGFAWIVLLLIGWMF 445
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
2-453 2.27e-143

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 418.04  E-value: 2.27e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGP-AVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYA 80
Cdd:COG0833     4 SEKQNKLKRGLKSRHLSMIALGGVIGTGLFLASGYTISQAGPgGALLAYLLGGLMVYFLMTSLGELAVAMPVSGSFQTYA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  81 SHYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTA 160
Cdd:COG0833    84 TRFIDPAFGFAVGWNYWLNWAITVAAELTAAGIIMQYWFPDVPVWIWSLLFLALIFLLNALSVKAFGESEFWFSLIKVIT 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 161 IIAMIIGGMAIMvygFGQETDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINA 240
Cdd:COG0833   164 VIAFIIVGLLMI---FGIIGGHAPGFSNFTTGDGPFPGGFLAILGVMMIVGFSFQGTELIGIAAGESENPEKTIPKAIRQ 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 241 VPFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQA 320
Cdd:COG0833   241 VFWRILLFYILAIFVIAALIPYTDAGVAESPFTLVFERAGIPYAADIMNAVILTAVLSAGNSGLYASTRMLWSLAKEGMA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 321 PKSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKE--EVKTLKF 398
Cdd:COG0833   321 PKIFAKLNKRGVPLNALLATMAVGLLALLSSFFGAGTVYLWLLSISGLTGFIAWLGIAISHYRFRRAYVAQggDLEDLKY 400
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1592456265 399 PVPMWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFLGIKKNT 453
Cdd:COG0833   401 KAPLFPFGPIFAFILCLIVIIGQAFDPEQRIALYIGIPFFLACYLGYKLKKKTKL 455
PRK10238 PRK10238
aromatic amino acid transporter AroP;
2-451 3.57e-132

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 389.31  E-value: 3.57e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYAS 81
Cdd:PRK10238    4 QQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAY 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  82 HYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAI 161
Cdd:PRK10238   84 KYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAV 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 162 IAMIIGGMAIMVYGFGQETdhvTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:PRK10238  164 VAMIIFGGWLLFSGNGGPQ---ATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAP 321
Cdd:PRK10238  241 IYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAP 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 322 KSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTlKFPVP 401
Cdd:PRK10238  321 KALASVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGVVT-RFPAL 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 1592456265 402 MWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFLGIKK 451
Cdd:PRK10238  400 LYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT 449
PRK10249 PRK10249
phenylalanine transporter; Provisional
3-451 2.68e-128

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 379.72  E-value: 2.68e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   3 NNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASH 82
Cdd:PRK10249   14 NQEPTLHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYK 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  83 YLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAII 162
Cdd:PRK10249   94 YWGPFAGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFALIKVLAII 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 163 AMIIGGMAIMVYGFGQETdhvTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVP 242
Cdd:PRK10249  174 GMIGFGLWLLFSGHGGEK---ASIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEKSIPKAVNQVV 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 243 FRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPK 322
Cdd:PRK10249  251 YRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPK 330
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 323 SFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTlKFPVPM 402
Cdd:PRK10249  331 FLTRVSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRFRAAMRRQGRET-QFKALL 409
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1592456265 403 WPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFLGIKK 451
Cdd:PRK10249  410 YPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFVAFKTLRRK 458
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
5-457 1.21e-127

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 378.31  E-value: 1.21e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   5 ETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYL 84
Cdd:PRK11049   15 EQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLL 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  85 GPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAM 164
Cdd:PRK11049   95 GPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGEMEFWFAMIKIVAIVAL 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 165 IIGGMAIMVYGFGQETDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFR 244
Cdd:PRK11049  175 IVVGLVMVAMHFQSPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIR 254
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 245 ILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSF 324
Cdd:PRK11049  255 IIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAF 334
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 325 TKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPN--EIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTlKFPVPM 402
Cdd:PRK11049  335 AKLSKRAVPAKGLTFSCICLLGGVVLLYVNPSviGAFTLVTTVSAILFMFVWTIILCSYLVYRKQRPHLHEKS-IYKMPL 413
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1592456265 403 WPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFLGIKKNTSQNR 457
Cdd:PRK11049  414 GKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELR 468
PRK10746 PRK10746
putative transport protein YifK; Provisional
1-447 4.91e-120

putative transport protein YifK; Provisional


Pssm-ID: 182694  Cd Length: 461  Bit Score: 358.36  E-value: 4.91e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   1 MQNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYA 80
Cdd:PRK10746    1 MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  81 SHYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTA 160
Cdd:PRK10746   81 HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 161 IIAMIIGGMAIMVYGFGQETdHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINA 240
Cdd:PRK10746  161 IIVMIVIGLGVIFFGFGNGG-QSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGK 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 241 VPFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQA 320
Cdd:PRK10746  240 VLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQL 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 321 PKSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPN--EIFVIIASIATFATVWVWLMILLSQVAMRsKMSKEEVKTLKF 398
Cdd:PRK10746  320 PAAMAKVSRHGVPVAGVAVSILILLVGSCLNYIIPNpqRVFVYVYSASVLPGMVPWFVILISQLRFR-RAHKAAIASHPF 398
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1592456265 399 PVPMWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFL 447
Cdd:PRK10746  399 RSILFPWANYLTMAFLICVLIGMYFNEDTRMSLFVGIIFLLAVTLIYKV 447
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
7-432 5.27e-94

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 291.39  E-value: 5.27e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   7 QLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGP 86
Cdd:TIGR01773   9 KLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAIGR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  87 LAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMII 166
Cdd:TIGR01773  89 WAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAFII 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 167 GGmAIMVYGFGQETDhVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRIL 246
Cdd:TIGR01773 169 LG-AVAIFGFAPGSE-VSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWRII 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 247 LFYVLTLFILMCIYPWNQIG-QEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSFT 325
Cdd:TIGR01773 247 VFYLGSIFIVVALLPWNSPNlLEVGSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPRVFM 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 326 KLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMsKEEVKTLKFPVPMWPI 405
Cdd:TIGR01773 327 KLNKKGVPVQAVLASTFFSFLTVVVNYFAPDKVFLFLVNSSGAIALLVYLVIAVSQLRMRKKL-KANGEAIKIRMWLYPW 405
                         410       420
                  ....*....|....*....|....*..
gi 1592456265 406 APILTIIFMVFIIILLGYFEKTRIALI 432
Cdd:TIGR01773 406 LTWLVIIFICGILVSMLFIPSMRDEVL 432
PRK15049 PRK15049
L-asparagine permease;
1-455 4.86e-91

L-asparagine permease;


Pssm-ID: 185009  Cd Length: 499  Bit Score: 285.36  E-value: 4.86e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   1 MQNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYA 80
Cdd:PRK15049   19 LNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYA 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  81 SHYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLW--FPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKV 158
Cdd:PRK15049   99 REFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWgaFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEFWFALIKV 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 159 TAIIAMIIGGMAIMvyGFGQETD-HVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKA 237
Cdd:PRK15049  179 LAIVTFLVVGTVFL--GSGQPLDgNTTGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKA 256
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 238 INAVPFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQE 317
Cdd:PRK15049  257 INSVIWRIGLFYVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMAMG 336
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 318 GQAPKSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLK 397
Cdd:PRK15049  337 GSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIIVCQMRLRKAIKEGKAADVS 416
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1592456265 398 FPVPMWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFLGIKKNTSQ 455
Cdd:PRK15049  417 FKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIAALPIIGILLVIGWFGVRKRVAE 474
AA_permease pfam00324
Amino acid permease;
16-456 1.04e-90

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 283.44  E-value: 1.04e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  16 HIRFMALGSAIGTGLFYGSAAAIQQAGPA-VLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGPLAGFLTGW 94
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAgALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  95 NYIFEMLIVCLADVTAFGFYMKLWFPHVE---QWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMIIGGMai 171
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWELVPDipyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGI-- 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 172 mVYGFGQETDHVTGISSLWEYGG---FMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLF 248
Cdd:pfam00324 159 -ILLSGGNPNDGAIFRYLGDNGGknnFPPGFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIF 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 249 YVLTLFILMCIYPWNQIG------QEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPK 322
Cdd:pfam00324 238 YILSLLAIGLLVPWNDPGllndsaSAASPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPK 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 323 SFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEVKTLKFPVPM 402
Cdd:pfam00324 318 FLKKVDKRGVPLRAILVSMVISLLALLLASLNPAIVFNFLLAISGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKA 397
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1592456265 403 W--PIAPILTIIFMVFIIILLGYFEKTR-------------IALIVGIAWVALLSITYFLGIKKNTSQN 456
Cdd:pfam00324 398 PlgPLGVILGLAAIIIILIIQFLYAFLPvpggpknwgagsfAAAYLIVLLFLIILIGVKLHVKNWKPQL 466
PRK11387 PRK11387
S-methylmethionine permease;
2-458 1.07e-90

S-methylmethionine permease;


Pssm-ID: 236904  Cd Length: 471  Bit Score: 283.28  E-value: 1.07e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPA-VLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYA 80
Cdd:PRK11387    6 SQQAGQFKRTMKVRHLVMLSLGGVIGTGLFFNTGYIISTTGAAgTLLAYLIGALVVYLVMQCLGELSVAMPETGAFHVYA 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  81 SHYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTA 160
Cdd:PRK11387   86 ARYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQVPVWPWCLLFCALIFGLNVVSTRFFAEGEFWFSLIKVVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 161 IIAMII-GGMAIMVYGFGQETDHVTGISSLWEYGGFmPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAIN 239
Cdd:PRK11387  166 ILAFIVlGGAAIFGFIPMQDGSPAPGLRNLTAEGWF-PHGGLPILMTMVAVNFAFSGTELIGIAAGETENPAKVIPVAIR 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 240 AVPFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQ 319
Cdd:PRK11387  245 TTIARLVIFFVGTVLVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNEGT 324
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 320 APKSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKE--EVKTLK 397
Cdd:PRK11387  325 LPACFARLTKRGIPLTALSVSMLGGLLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFMFRRRHLRDgkALSELA 404
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1592456265 398 FPVPMWPIAPILTIIFMVFIIILLGYFEKTRIALIVGIAWVALLSITYFLGIKKNTSQNRQ 458
Cdd:PRK11387  405 YRAPWYPLTPILGFVLCLLACVGLAFDPSQRIALWCGIPFVALCYGAYYLTQRLKRNMTQE 465
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
9-423 2.46e-84

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 267.23  E-value: 2.46e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   9 KRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPA-VLLAYLIGGAAVFMVMRALGEMAVHHPV-AGSFSHYASHYLGP 86
Cdd:TIGR00913   1 KKSLKQRHIQMIALGGTIGTGLLVGSGTALATGGPAgLLIGYAIMGSIIYCVMQSLGEMATFYPVvSGSFATYASRFVDP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  87 LAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMII 166
Cdd:TIGR00913  81 AFGFAVGWNYWLQWLIVLPLELVTASMTIQYWTDKVNPAVWIAIFYVFIVIINLFGVKGYGEAEFWFSSIKILAIIGFII 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 167 GGMaIMVYGFGQETDHVTGisSLWEYGGFMPNGIS-----GVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:TIGR00913 161 LSI-ILNCGGGPNHGYIGF--RYWHDPGAFAGGTIggrfkGVCSVFVTAAFSFGGTELVALTAGEAANPRKSIPRAAKRT 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWN---------QIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMY 312
Cdd:TIGR00913 238 FWRILVFYILTLFLIGFLVPYNdprllssssSSDSAASPFVIAIQNHGIKVLPHIFNAVILISVLSAANSSLYASSRTLY 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 313 GMAQEGQAPKSFTKLSRNGVPWMTVVVMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKM---- 388
Cdd:TIGR00913 318 ALAHQGLAPKIFAYVDRRGVPYVAVIVSSLFGLLAFLAVSKKEAEVFTWLLNISGLSGFFTWMCICLSHIRFRKAMkaqg 397
                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1592456265 389 -SKEEvktLKFPVPMWPIAPILTIIFMVFIIILLGY 423
Cdd:TIGR00913 398 rSLDE---LPYKSQTGPYGSYYALFFNILILIAQGY 430
PRK10836 PRK10836
lysine transporter; Provisional
8-422 7.50e-77

lysine transporter; Provisional


Pssm-ID: 182767  Cd Length: 489  Bit Score: 248.20  E-value: 7.50e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   8 LKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPA-VLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGP 86
Cdd:PRK10836   13 LRRELKARHLTMIAIGGSIGTGLFVASGATISQAGPGgALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEE 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  87 LAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMII 166
Cdd:PRK10836   93 GFGFALGWNYWYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFSLIKVTTVIVFII 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 167 GGMaIMVYGFGQETDHvTGISSlWEYG-GFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRI 245
Cdd:PRK10836  173 VGV-LMIIGIFKGAEP-AGWSN-WTIGdAPFAGGFAAMIGVAMIVGFSFQGTELIGIAAGESEDPAKNIPRAVRQVFWRI 249
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 246 LLFYVLTLFILMCIYPW-------NQIGQ-EGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQE 317
Cdd:PRK10836  250 LLFYVFAILIISLIIPYtdpsllrNDVKDiSVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACD 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 318 GQAPKSFTKLSRNGVP----WMTVVVMSAVLLIGVVLNyllpNEIFVIIASIATFATVWVWLMILLSQVAMRSK--MSKE 391
Cdd:PRK10836  330 GKAPRIFAKLSRGGVPrnalYATTVIAGLCFLTSMFGN----QTVYLWLLNTSGMTGFIAWLGIAISHYRFRRGyvLQGH 405
                         410       420       430
                  ....*....|....*....|....*....|.
gi 1592456265 392 EVKTLKFPVPMWPIAPILTiiFMVFIIILLG 422
Cdd:PRK10836  406 DLNDLPYRSGFFPLGPIFA--FVLCLIITLG 434
PRK10197 PRK10197
GABA permease;
20-421 4.71e-72

GABA permease;


Pssm-ID: 182297  Cd Length: 446  Bit Score: 234.52  E-value: 4.71e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  20 MALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGPLAGFLTGWNYIFE 99
Cdd:PRK10197    2 LSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWF 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 100 MLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMIIGGmAIMVYGFGQE 179
Cdd:PRK10197   82 WVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLG-AVAISGFYPY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 180 TDhVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLFYVLTLFILMCI 259
Cdd:PRK10197  161 AE-VSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVAL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 260 YPWNQIGQEG-SPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSFTKLSRNGVPWMTVV 338
Cdd:PRK10197  240 IPWNMPGLKAvGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPYVAVL 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 339 VMSAVLLIGVVLNYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRsKMSKEEVKTLKFPVPMWPIAPILTIIFMVFII 418
Cdd:PRK10197  320 LSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMR-KILRAEGSEIRLRMWLYPWLTWLVIGFITFVL 398

                  ...
gi 1592456265 419 ILL 421
Cdd:PRK10197  399 VVM 401
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
2-460 9.84e-62

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 207.06  E-value: 9.84e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   2 QNNETQLKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYAS 81
Cdd:COG0531     3 RGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYAR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  82 HYLGPLAGFLTGWNYIFEMLIVCLADVTAFGFYMKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAI 161
Cdd:COG0531    83 RALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 162 IAMIIGGMaimvygfgqetdhVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAV 241
Cdd:COG0531   163 LLFIVVGL-------------FAFDPANFTPFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILS 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 242 PFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAP 321
Cdd:COG0531   230 LLIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLP 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 322 KSFTKLS-RNGVPWMTVVVMSAVLLIGVvlnyLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMSKEEvKTLKFPv 400
Cdd:COG0531   310 KVFAKVHpRFGTPVNAILLTGVIALLLL----LLGAASFTALASLASVGVLLAYLLVALAVIVLRRRRPDLP-RPFRVP- 383
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 401 pmWPIAPILTIIFMVFIIILLGYfektrIALIVGIAWVALLSITYFLGIKKNTSQNRQIK 460
Cdd:COG0531   384 --LPLIPILGILLCLFLLYLLGP-----GALLIGLVLLAIGLLLYLLYRRRHPKLLKEAE 436
2A0306 TIGR00909
amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
8-447 8.59e-37

amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129987 [Multi-domain]  Cd Length: 429  Bit Score: 139.89  E-value: 8.59e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   8 LKRGLTGRHIRFMALGSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGPL 87
Cdd:TIGR00909   1 LSRELGLFDLTMLGIGAMIGTGIFVVTGIAAGKAGPAVILSFVLAGLTALFIALVYAELAAMLPVAGSPYTYAYEAMGEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  88 AGFLTGWNYIFEMLIVCLADVTAFGFYMK-------LWFPHV---------EQWIWVLSIVCFIGAINLCHVKIFGEMEF 151
Cdd:TIGR00909  81 TAFIIGWSLWLEYGVAVAAVAVGWGGYLQeflpgvgLDLPAVltakpgnggVFNLPALLIVLFLTYILYLGAKESGKVND 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 152 WLSIVKVTAIIAMIIGGMAIMvygfgqetdhvtgisSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNPE 231
Cdd:TIGR00909 161 ILVVLKVAALLLFAALGAIHF---------------ASNNYTPFMPMGFGGVGAATALVFFAFIGFEAISTAAEEVKNPE 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 232 KTIPKAINAVPFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMM 311
Cdd:TIGR00909 226 RDIPKAIILSLIVVTLLYVLVAAVILGAVPWRQLAGSTAPLSLVGYDLGQGIGGLILTAGAVFSIASVMLAGIYGTSRVL 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 312 YGMAQEGQAPKSFTKLS-RNGVPWMTVVVMSavlLIGVVLNYLLPNEIFVIIASIAT---FATVWVWLMIL-LSQVAMRS 386
Cdd:TIGR00909 306 FAMSRDGLLPGSLSKVHpKTGTPHMSIIIFS---LTAALLASLVPLEGLAELTSIGTliaFAAVNVAVIILrRRRPDIQR 382
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1592456265 387 kmskeevktlKFPVPMWPIAPILTIIFMVFIIILLGYfektrIALIVGIAWVALLSITYFL 447
Cdd:TIGR00909 383 ----------AFRCPLVPVLPVLVVSYCIYLLLNLGP-----GTTVWFLVWMLLGSVFYFI 428
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
5-402 3.29e-30

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 123.00  E-value: 3.29e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   5 ETQLKRGLTGRHIRFMALGSAIGTGLF-YGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHY 83
Cdd:TIGR00906  23 ESKMKRCLTTWDLMALGIGSTIGAGIYvLTGEVARNDSGPAIVLSFLISGLAAVLSGFCYAEFGARVPKAGSAYLYSYVT 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  84 LGPLAGFLTGWNYIFEMLIVCLADVTAF-GFYMKLWFPHVEQWIWV------------LSIVCFIGAINLCHVKIFGEME 150
Cdd:TIGR00906 103 VGELWAFITGWNLILEYVIGTAAVARSWsAYFDELLNKQIGQFRRTyfklnydglaeyPDFFAVCLILLLAVLLSFGVKE 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 151 FwlSIVKVTAIIAMIIGGMAIMVYGFGQETDHVTGISSLWEYGGFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNP 230
Cdd:TIGR00906 183 S--AWVNKIFTAINILVLLFVIIAGFTKADVANWSITEEKGAGGFMPYGFTGVLSGAATCFFAFIGFDAIATTGEEVKNP 260
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 231 EKTIPKAINAVPFRILLFYVLTLFILMCIYPWNQIgQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRM 310
Cdd:TIGR00906 261 QRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLL-DPDAPFPVAFEYVGWDPAKYIVAVGALCGMSTSLLGGMFPLPRV 339
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 311 MYGMAQEGQAPKSFTKL-SRNGVPWMTVVVMSAvllIGVVLNYLLPNEIFVIIASIAT---FATVWVWLMILLSQVAMRS 386
Cdd:TIGR00906 340 IYAMARDGLLFKWLAQInSKTKTPINATVVSGA---IAALMAFLFDLKALVDLLSIGTllaYSLVAACVLILRYQPGLVY 416
                         410
                  ....*....|....*...
gi 1592456265 387 KMSK--EEVKTLKFPVPM 402
Cdd:TIGR00906 417 DQAKdtDEKDTLDSWVPF 434
AA_permease_2 pfam13520
Amino acid permease;
19-420 5.69e-25

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 106.63  E-value: 5.69e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  19 FMALGSAIGTGLFYGSAAAiqQAGPAVLLAYLIG-GAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGPLAGFLTGWNY- 96
Cdd:pfam13520   8 ALVIGSVIGSGIFVAPLVA--SGGPALIVWGWIAaIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNw 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  97 IFEMLIVCLADVTAFGFYMKLWFPHVEQWIW---VLSIVCFIG--AINLCHVKIFGEMEFWLSIVKVTAIIAMIIggmAI 171
Cdd:pfam13520  86 FAYVLGLASSASVAASYLLSALGPDLVPTTWltyGIAIAILIIfaIINIRGVRESAKIQNILGILKLLLPLILII---IL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 172 MVYGFGQetDHVTGISSLWEYggFMPNGISGVIASLAIVMFAFGGIEVIGITASEAKNpeKTIPKAINAVPFRILLFYVL 251
Cdd:pfam13520 163 GLVTADG--GGFNLLSGEWHT--FFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVKK--RNVPKAIFIGVIIVGVLYIL 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 252 TLFILMCIYPWNQI---GQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKS--FTK 326
Cdd:pfam13520 237 VNIAFFGVVPDDEIalsSGLGQVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSrfFAK 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 327 LSRNGVPWMTVVVMSAVLLIGVVLnYLLPNEIFVIIASIATFATVWVWLMILLSQVAMRSKMskeEVKTLKFPVPMWPIA 406
Cdd:pfam13520 317 VNKFGSPIRAIILTAILSLILLLL-FLLSPAAYNALLSLSAYGYLLSYLLPIIGLLILRKKR---PDLGRIPGRWPVAIF 392
                         410
                  ....*....|....
gi 1592456265 407 PILTIIFMVFIIIL 420
Cdd:pfam13520 393 GILFSLFLIVALFF 406
PRK11021 PRK11021
putative transporter; Provisional
24-362 2.54e-12

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 68.40  E-value: 2.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  24 SAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLGPLAGFLTGWnyIFEMLI- 102
Cdd:PRK11021   13 SLLGTGVFAVPALAALVAGNNSLWAWPLLILLIFPIAIVFARLGRHFPHAGGPAHFVGMAFGPRLGRVTGW--LFLSVIp 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 103 --VCLADVTAFGFYMKLW-FPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMIIGGmaimvyGFGQE 179
Cdd:PRK11021   91 vgLPAALQIAAGFGQALFgWSSWQLLLAELLTLALLWLLNLRGASSSANLQTVIALLIVALVVAIWWAG------DIKPA 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 180 TDHVTGISSLweyggfmpnGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLFYVLTLFILMCI 259
Cdd:PRK11021  165 DIPFPAPGSI---------EWSGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALMIGLLLAGLVYWACTVVVLHF 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 260 YPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSFTKLSRNGVPWMTVVV 339
Cdd:PRK11021  236 PAYGDKQAAAASLPGIFVQLFGGYALWVICVIGYLACFASVNIYTQSFARLVWSQAREGRPPSYLARLSARGVPVNALNA 315
                         330       340       350
                  ....*....|....*....|....*....|...
gi 1592456265 340 MSAVLLIGVVLNYLL----------PNEIFVII 362
Cdd:PRK11021  316 VLGCCAVSILLIYALglnlealiayANGIFVLI 348
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
23-449 4.59e-12

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 67.85  E-value: 4.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  23 GSAIGTGLFYGSAAAIQQAGPAVLLAYLIGGAAVFMVMRAL--GEMAVHHPVAGSFSHYASHYLGPLAGFLTGWnyiFEM 100
Cdd:TIGR00911  55 GTIIGSGIFVSPKGVLKNAGSVGLALIMWAVCGIFSIVGALvyAELGTTIPKSGGEYNYILEVFGPLLAFLRLW---IEL 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 101 LIV----CLADVTAFGFY-MKLWFPHVEQWIWVLSIVCFIG-----AINLCHVKIFGEMEFWLSIVKVTAIIAMIIGGMa 170
Cdd:TIGR00911 132 LVIrpgsQAVNALNFAIYiLTPVFPDCEVPEWAIRLVAVLCvllltLVNCLSVKWATRVQDIFTACKLLALLLIIITGW- 210
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 171 imVYGFGQETDHVTGISSlweYGGFMPNgISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLFYV 250
Cdd:TIGR00911 211 --VQLGKGGVESLNPKNA---FEGTETS-AGGIVLAFYSGIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVTFIYV 284
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 251 LTLFILMCIYPWNQIGQEGSPFVQiFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSFTKLSR- 329
Cdd:TIGR00911 285 LTNIAYFTVLSPEELLASLAVAVD-FGERLLGVMSWAMPALVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVk 363
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 330 --NGVPWMTVVVMSAVLligvvlnYLLPNEIFVIIASIATFATVWVWlMILLSQVAMRSKmSKEEVKTLKFPVpmwpIAP 407
Cdd:TIGR00911 364 rlTPLPSLLIVCTLTLL-------MLFSGDIYSLINLISFANWLFNA-LAVAGLLWLRYK-RPEMNRPIKVPL----FFP 430
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 1592456265 408 ILTIIFMVFIIILLGYFEKTrialIVGIAWVALLSI--TYFLGI 449
Cdd:TIGR00911 431 VFFLLSCLFLIILSLYSPPV----GCGVGFIIMLTGvpVYFFGV 470
frlA PRK11357
amino acid permease;
1-346 5.59e-12

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 67.57  E-value: 5.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265   1 MQNNETQLKRGLTGrhIRFMALGSAIGTGLFYGSAAAIQQAGPAVL--LAYLIGGAAVFMVMRALGEMAVHHPVAGSFSH 78
Cdd:PRK11357    1 MGSQELQRKLGFWA--VLAIAVGTTVGSGIFVSVGEVAKAAGTPWLtvLAFVIGGLIVIPQMCVYAELSTAYPENGADYV 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  79 YASHYLGPLAGFLTGWNYIF-----EMLIVCLADVTAFGFYMKlWFPHVEQWIWVLSIVCFIgAINLCHVKIFGEMEFWL 153
Cdd:PRK11357   79 YLKNAGSRPLAFLSGWASFWandapSLSIMALAIVSNLGFLTP-IDPLLGKFIAAGLIIAFM-LLHLRSVEGGAAFQTLI 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 154 SIVKVTAIIAMI-IGGMAIMVYGFGQETDHVTGISslweyGGFMpngisGVIASLAIVMFAFGGIEVIGITASEAKNPEK 232
Cdd:PRK11357  157 TIAKIIPFTIVIgLGIFWFKAENFAAPTTTAIGAT-----GSFM-----ALLAGISATSWSYTGMASICYMTGEIKNPGK 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 233 TIPKAINAVPFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSL-GINSAAN----ILNIVVITAAVSainSDIFGA 307
Cdd:PRK11357  227 TMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWIpALGSTAGifvaITAMIVILGSLS---SCVMYQ 303
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1592456265 308 GRMMYGMAQEGQAPKSFTKLS-RNGVPWMTVVVMSAVLLI 346
Cdd:PRK11357  304 PRLEYAMAKDNLFFKCFGHVHpKYNTPDVSIILQGALGIF 343
PRK10644 PRK10644
arginine/agmatine antiporter;
19-371 8.91e-10

arginine/agmatine antiporter;


Pssm-ID: 182613 [Multi-domain]  Cd Length: 445  Bit Score: 60.57  E-value: 8.91e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  19 FMALGSAIGTGLFYGSAAAIQQAGPAVL--LAYLIGGAAVFMVMRALGEMAvhhPVAGSFSHYASHYLGPLAGFLTGWNY 96
Cdd:PRK10644   17 LMVAGNIMGSGVFLLPANLASTGGIAIYgwLVTIIGALGLSMVYAKMSSLD---PSPGGSYAYARRCFGPFLGYQTNVLY 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  97 IFEMLIVCLADVTAFGFYMKLWFPHVEQWIwVLSIVCFIGAINLCHVKIFGEmEFWLSIVKVTAIIAMI-IGGMAIMVYG 175
Cdd:PRK10644   94 WLACWIGNIAMVVIGVGYLSYFFPILKDPL-VLTITCVVVLWIFVLLNIVGP-KMITRVQAVATVLALIpIVGIAVFGWF 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 176 FGQETDHVTGisslWEYGGFmpNGISGVIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLFYVLTLFI 255
Cdd:PRK10644  172 WFRGETYMAA----WNVSGL--GTFGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCYVLSSTA 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 256 LMCIYPWNQIGQEGSPFVQIFSSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSFTKLSRNGVPWM 335
Cdd:PRK10644  246 IMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVA 325
                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1592456265 336 TVVVMsAVLLIGVVLNYLLPN--EIFVIIASIATFATV 371
Cdd:PRK10644  326 GLLIV-GVLMTIFQLSSISPNasKEFGLVSSVSVIFTL 362
cadB PRK10435
cadaverine/lysine antiporter;
203-351 9.71e-05

cadaverine/lysine antiporter;


Pssm-ID: 182458  Cd Length: 435  Bit Score: 44.74  E-value: 9.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 203 VIASLAIVMFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLFYVLTLFILMCIYPWNQIGQEGSPFVQIFSSLGIN 282
Cdd:PRK10435  189 IIKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLGTGLAGIIYIAATQVISGMFPASVMAASGAPFAISASTILGN 268
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1592456265 283 SAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKSFTKLSRNGVP----WMTVVVMSAVLLIGVVLN 351
Cdd:PRK10435  269 WAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDKNGIPkkglLLAAVKMTALMILITLMN 341
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
43-372 1.69e-04

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 43.97  E-value: 1.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265  43 PAVLLAYLIGGAAVFMVMRALGEMAVHHPVAGSFSHYASHYLG----PLAGFLTGW-NYIFEMLIVC---LADVTAFGFY 114
Cdd:TIGR00907  47 MSIVWGWIIAGAGSICIALSLAELSSAYPTSGGQYFWSAKLAPprqmPFASWMTGWfNLAGQVAGTAstdLSVAQLILGI 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 115 MKLWFPHVEQWIWVLSIVCFIGAINLCHVKIFGEMEFWLSIVKVTAIIAMIIGGMAIMVYGFGQE-TDHVTGISSLWEY- 192
Cdd:TIGR00907 127 VSLTTPGREYIPTRWHIFGIMIGIHLIHALINSLPTKWLPRITSSAAYWSLLGFLTICITLLACKsPKFNDGKFVFTNFn 206
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 193 ---GGFMPNGISGVIASLAiVMFAFGGIEVIGITASEAKNPEKTIPKAI-NAVPFRILLFYVLTLFILMCIYPWNQIGQE 268
Cdd:TIGR00907 207 nstGGWKPGGFAFLLGLLN-PAWSMTGYDGTAHMAEEIENPEVVGPRAIiGAVAIGIVTGFCFNIVLFFSMGDIDSLISS 285
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 269 --GSPFVQIF-SSLGINSAANILNIVVITAAVSAINSDIFGAGRMMYGMAQEGQAPKS--FTKLS-RNGVPwMTVVVMSA 342
Cdd:TIGR00907 286 ttGQPIAQIFyNALGNKAGAIFLLCLILVTSFFCAITCMTANSRMIYAFSRDGGLPFSplWSRVNpRTQVP-LNAVWLSA 364
                         330       340       350
                  ....*....|....*....|....*....|
gi 1592456265 343 VLLIGVVLNYLLPNEIFVIIASIATFATVW 372
Cdd:TIGR00907 365 VWIILIGLLGLGSSTAFQAIFSVCTVALDV 394
PRK15238 PRK15238
inner membrane transporter YjeM; Provisional
124-265 1.05e-03

inner membrane transporter YjeM; Provisional


Pssm-ID: 237929 [Multi-domain]  Cd Length: 496  Bit Score: 41.46  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1592456265 124 QWIWVLSIvCFIGAINLCHVKIFGemefwlSIVKVTAI---------IAMIIGGMAIMVYGFGQETDHVTGISslweygg 194
Cdd:PRK15238  133 QVVGILAV-IWMILVTFVASKGIN------KIAKVTSIggiavmllnIVLLLVSIIILILNGGHFAQPIGVSS------- 198
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1592456265 195 FM--PN-GISGVIASLAIV---MFAFGGIEVIGITASEAKNPEKTIPKAINAVPFRILLFYVLTLFILMCIYPWNQI 265
Cdd:PRK15238  199 FVtsPNpAYQSPIAVLSFVvfaIFAYGGIEAVGGLVDKTENPEKNFPKGIIIAAIVISIGYSLAIFLWGVSTNWQQV 275
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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