NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1553404610|ref|WP_127801384|]
View 

MULTISPECIES: AraC family transcriptional regulator [Acinetobacter]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11454391)

helix-turn-helix (HTH) domain-containing protein with an AraC family HTH domain, binds DNA and may function as a transcriptional regulator

CATH:  1.10.10.60
Gene Ontology:  GO:0003700|GO:0003677
PubMed:  10473770|15808743|8831795

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
93-347 1.14e-17

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


:

Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 81.75  E-value: 1.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610  93 YMASRSNSVAEALQYIAQFSRLVIDANEAVPMQIQQQDDLLIVSWPNPQDQSTLIHEITFACMLQLARQMFAAEHFPLRR 172
Cdd:COG2207     1 LRLLILLLLLLLLLALLLLLLLLLLLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 173 VHFAHAPQTALYQYQKFYGCEVLFDQPDYQLVLSIDSLQLQPQQPDPTLIGILKKQAEEAMAAKPLLEGLDQKLRHLIAD 252
Cdd:COG2207    81 LLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 253 YLRLQQQAPKLDELAVELCMSSRTLQRQLS-ELGTSFKQLLDMERIKR-CELLLPQKLSLTEIASQLGYSDQSALARAYK 330
Cdd:COG2207   161 LLLLLLLLLTLEELARELGLSPRTLSRLFKeETGTSPKQYLRELRLERaKRLLAETDLSISEIAYELGFSSQSHFSRAFK 240

                         250
                  ....*....|....*..
gi 1553404610 331 AHCGQTLTERRRVLRQQ 347
Cdd:COG2207   241 KRFGVTPSEYRKRLRAR 257
 
Name Accession Description Interval E-value
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
93-347 1.14e-17

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 81.75  E-value: 1.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610  93 YMASRSNSVAEALQYIAQFSRLVIDANEAVPMQIQQQDDLLIVSWPNPQDQSTLIHEITFACMLQLARQMFAAEHFPLRR 172
Cdd:COG2207     1 LRLLILLLLLLLLLALLLLLLLLLLLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 173 VHFAHAPQTALYQYQKFYGCEVLFDQPDYQLVLSIDSLQLQPQQPDPTLIGILKKQAEEAMAAKPLLEGLDQKLRHLIAD 252
Cdd:COG2207    81 LLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 253 YLRLQQQAPKLDELAVELCMSSRTLQRQLS-ELGTSFKQLLDMERIKR-CELLLPQKLSLTEIASQLGYSDQSALARAYK 330
Cdd:COG2207   161 LLLLLLLLLTLEELARELGLSPRTLSRLFKeETGTSPKQYLRELRLERaKRLLAETDLSISEIAYELGFSSQSHFSRAFK 240

                         250
                  ....*....|....*..
gi 1553404610 331 AHCGQTLTERRRVLRQQ 347
Cdd:COG2207   241 KRFGVTPSEYRKRLRAR 257
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 57-212 2.82e-17

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


Pssm-ID: 432679  Cd Length: 185  Bit Score: 78.84  E-value: 2.82e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610  57 QAFIALLEQTRQQLNTAYLVFELARFIRPEHFGVLGYMASRSNSVAEALQYIAQFSRLVIDAneAVPMQIQQQDDLLIVS 136
Cdd:pfam12625  28 DQYLRLWEAAARELGDPALGLRLGRRLRPGSLGLLGYAALSSPTLGEALDRLLRYLRLLSDA--LELRLEEGEGGLARLR 105

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1553404610 137 W---PNPQDQSTLIHEITFACMLQLARQMfAAEHFPLRRVHFAHAPQTALYQYQKFYGCEVLFDQPDYQLVLSIDSLQL 212
Cdd:pfam12625 106 LdvrPIPGRRRDFLLELALAALLRLARWL-LGRRLPPLRVEFPHPAPADAAEYERLFGCPVRFGAPRNALVFDAADLDR 183
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
261-336 9.64e-17

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 74.13  E-value: 9.64e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1553404610  261 PKLDELAVELCMSSRTLQRQL-SELGTSFKQLLDMERIKRC-ELLLPQKLSLTEIASQLGYSDQSALARAYKAHCGQT 336
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFkKETGTTPKQYLRDRRLERArRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVT 79
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 221-345 5.22e-07

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 50.80  E-value: 5.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 221 LIGILKKQAEEAMAAKPLLEGLDQKLRHLIADYLRLQQQAPklDELAVELCMSSRTLQRQLSELGTSFKQLLDMERIKRC 300
Cdd:PRK09685  177 LIALLRPALHQRESVQPRRERQFQKVVALIDQSIQEEILRP--EWIAGELGISVRSLYRLFAEQGLVVAQYIRNRRLDRC 254

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1553404610 301 ELLL---PQKLSLTEIASQLGYSDQSALARAYKAHCGQTLTERRRVLR 345
Cdd:PRK09685  255 ADDLrpaADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRKFR 302
 
Name Accession Description Interval E-value
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
93-347 1.14e-17

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 81.75  E-value: 1.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610  93 YMASRSNSVAEALQYIAQFSRLVIDANEAVPMQIQQQDDLLIVSWPNPQDQSTLIHEITFACMLQLARQMFAAEHFPLRR 172
Cdd:COG2207     1 LRLLILLLLLLLLLALLLLLLLLLLLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 173 VHFAHAPQTALYQYQKFYGCEVLFDQPDYQLVLSIDSLQLQPQQPDPTLIGILKKQAEEAMAAKPLLEGLDQKLRHLIAD 252
Cdd:COG2207    81 LLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 253 YLRLQQQAPKLDELAVELCMSSRTLQRQLS-ELGTSFKQLLDMERIKR-CELLLPQKLSLTEIASQLGYSDQSALARAYK 330
Cdd:COG2207   161 LLLLLLLLLTLEELARELGLSPRTLSRLFKeETGTSPKQYLRELRLERaKRLLAETDLSISEIAYELGFSSQSHFSRAFK 240

                         250
                  ....*....|....*..
gi 1553404610 331 AHCGQTLTERRRVLRQQ 347
Cdd:COG2207   241 KRFGVTPSEYRKRLRAR 257
Arabinose_bd pfam12625
Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial ...
 57-212 2.82e-17

Arabinose-binding domain of AraC transcription regulator, N-term; AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].


Pssm-ID: 432679  Cd Length: 185  Bit Score: 78.84  E-value: 2.82e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610  57 QAFIALLEQTRQQLNTAYLVFELARFIRPEHFGVLGYMASRSNSVAEALQYIAQFSRLVIDAneAVPMQIQQQDDLLIVS 136
Cdd:pfam12625  28 DQYLRLWEAAARELGDPALGLRLGRRLRPGSLGLLGYAALSSPTLGEALDRLLRYLRLLSDA--LELRLEEGEGGLARLR 105

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1553404610 137 W---PNPQDQSTLIHEITFACMLQLARQMfAAEHFPLRRVHFAHAPQTALYQYQKFYGCEVLFDQPDYQLVLSIDSLQL 212
Cdd:pfam12625 106 LdvrPIPGRRRDFLLELALAALLRLARWL-LGRRLPPLRVEFPHPAPADAAEYERLFGCPVRFGAPRNALVFDAADLDR 183
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
261-336 9.64e-17

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 74.13  E-value: 9.64e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1553404610  261 PKLDELAVELCMSSRTLQRQL-SELGTSFKQLLDMERIKRC-ELLLPQKLSLTEIASQLGYSDQSALARAYKAHCGQT 336
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFkKETGTTPKQYLRDRRLERArRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVT 79
HTH_18 pfam12833
Helix-turn-helix domain;
266-342 3.24e-16

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 72.62  E-value: 3.24e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 266 LAVELCMSSRTLQRQL-SELGTSFKQLLDMERIKRCELLLPQK--LSLTEIASQLGYSDQSALARAYKAHCGQTLTE-RR 341
Cdd:pfam12833   1 LAAALGMSPRTLSRLFkRELGLSPKEYLRRLRLERARRLLLEDtgLSVAEIALALGFSDASHFSRAFRRLFGLTPSEyRR 80


                  .
gi 1553404610 342 R 342
Cdd:pfam12833  81 R 81
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 244-342 2.54e-13

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 69.80  E-value: 2.54e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 244 QKLRHLIADYLrlqQQAPKLDELAVELCMSSRTLQRQ-LSELGTSFKQLLDMERIKR-CELLLPQKLSLTEIASQLGYSD 321
Cdd:COG4977   213 ARAQAWMEANL---EEPLSVDELARRAGMSPRTLERRfRAATGTTPARYLQRLRLERaRRLLETTDLSIEEIAAACGFGS 289

                          90       100
                  ....*....|....*....|.
gi 1553404610 322 QSALARAYKAHCGQTLTERRR 342
Cdd:COG4977   290 ASHFRRAFRRRFGVSPSAYRR 310
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 229-342 7.63e-12

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 65.85  E-value: 7.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 229 AEEAMAA--------KPLLEGLDQKLRHLIADYLRL----QQQAPKLDELAVELCMSSRTLQRQL-SELGTSFKQLLDME 295
Cdd:COG2169    57 AAAAEAAgfrpckrcRPDLAPGSPPRADLVARACRLieagAEDRPSLEDLAARLGLSPRHLRRLFkAHTGVTPKAYARAR 136

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1553404610 296 RIKRCELLLPQKLSLTEIASQLGYSDQSALARAYKAHCGQTLTERRR 342
Cdd:COG2169   137 RLLRARQLLQTGLSVTDAAYAAGFGSLSRFYEAFKKLLGMTPSAYRR 183
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 221-345 5.22e-07

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 50.80  E-value: 5.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 221 LIGILKKQAEEAMAAKPLLEGLDQKLRHLIADYLRLQQQAPklDELAVELCMSSRTLQRQLSELGTSFKQLLDMERIKRC 300
Cdd:PRK09685  177 LIALLRPALHQRESVQPRRERQFQKVVALIDQSIQEEILRP--EWIAGELGISVRSLYRLFAEQGLVVAQYIRNRRLDRC 254

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1553404610 301 ELLL---PQKLSLTEIASQLGYSDQSALARAYKAHCGQTLTERRRVLR 345
Cdd:PRK09685  255 ADDLrpaADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRKFR 302
ftrA PRK09393
transcriptional activator FtrA; Provisional
 235-342 6.85e-06

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 47.27  E-value: 6.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 235 AKPLLEGLDQKLRHLIaDYLRLQQQAP-KLDELAVELCMSSRTLQRQLSEL-GTSFKQLLDMERIKRC-ELLLPQKLSLT 311
Cdd:PRK09393  209 PRPVASRESDRLGPLI-DWMRAHLAEPhTVASLAARAAMSPRTFLRRFEAAtGMTPAEWLLRERLARArDLLESSALSID 287

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1553404610 312 EIASQLGYSDQSALARAYKAHCGQTLTERRR 342
Cdd:PRK09393  288 QIAERAGFGSEESLRHHFRRRAATSPAAYRK 318
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
262-342 2.58e-04

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 42.27  E-value: 2.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 262 KLDELAVELCMS-SRT--LQRQlsELGTSFKQLLDMERIKRCELLL-PQKLSLTEIASQLGYSDQSALARAYKAHCGQTL 337
Cdd:PRK10572  201 DIESVAQHVCLSpSRLahLFRQ--QLGISVLRWREDQRISRAKLLLqTTRMPIATIGRNVGYDDQLYFSRVFKKCTGASP 278


                  ....*
gi 1553404610 338 TERRR 342
Cdd:PRK10572  279 SEFRA 283
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 262-330 4.87e-04

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 41.52  E-value: 4.87e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 262 KLDELAVELCMSSRTLQRQLSELGTSFKQLLDMERIKRC-ELLLPQKLSLTEIASQLGYSDQSALARAYK 330
Cdd:PRK15185  224 KLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAaKLLRIGNHNVNAVALKCGYDSTSYFIQCFK 293
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 263-339 6.03e-04

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 41.06  E-value: 6.03e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1553404610 263 LDELAVELCMSSRTLQRQLSELGTSFKQLLDMERIKRC-ELLLPQKLSLTEIASQLGYSDQSALARAYKAHCGQTLTE 339
Cdd:PRK09978  161 LARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRAlQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTE 238
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 262-336 3.01e-03

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 38.91  E-value: 3.01e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1553404610 262 KLDELAVELCMSSRTLQRQLSELGTSFKQLLDMERIKRCELLLPQKLSLTEIASQLGYSDQSALARAYKAHCGQT 336
Cdd:PRK09940  152 KLKDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNS 226
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 306-342 4.65e-03

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 34.44  E-value: 4.65e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1553404610 306 QKLSLTEIASQLGYSdQSALARAYKAHCGQTLTERRR 342
Cdd:pfam00165   7 TNLTIADIADELGFS-RSYFSRLFKKYTGVTPSQYRH 42
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
155-348 9.29e-03

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 37.45  E-value: 9.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 155 MLQLARQMFAAEHFPLRRVHFAHAPQTALYQYQKFYGCEVLFDQPDYQLVLSIDSLQLQPQQPDPTLIGILKKQAEEAMA 234
Cdd:COG2207    16 LLLLLLLLLLLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1553404610 235 AKPLLEGLDQKLRHLIADYLRLQQQAPKLDELAVELCMSSRTLQRQLSELGTSFKQLLDMERIKRCELLLPQKLSLTEIA 314
Cdd:COG2207    96 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELA 175

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1553404610 315 SQLGYSdQSALARAYKAHCGQTLTERRRVLRQQQ 348
Cdd:COG2207   176 RELGLS-PRTLSRLFKEETGTSPKQYLRELRLER 208
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH