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Conserved domains on  [gi|1539065270|ref|WP_125892187|]
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MULTISPECIES: GntR family transcriptional regulator [Providencia]

Protein Classification

GntR family transcriptional regulator( domain architecture ID 11706244)

GntR family transcriptional regulator binds a specific ligand that modulates DNA binding and the expression of genes encoding fatty acid biosynthetic and degrading enzymes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GntR COG1802
DNA-binding transcriptional regulator, GntR family [Transcription];
97-298 1.77e-27

DNA-binding transcriptional regulator, GntR family [Transcription];


:

Pssm-ID: 441407 [Multi-domain]  Cd Length: 222  Bit Score: 106.16  E-value: 1.77e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270  97 QMIKRKELMPGDTFTELQLAKKSHVSSSVVREFLVEFSRYGLIKNTHRGNWHMMKFSREYAEKLFEFRELLETNALTHFL 176
Cdd:COG1802    22 EAILSGELPPGERLSEAELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAPLSPEEIRELYEVRAALEGLAARLAA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270 177 NLPADDHRwilaKELLLKHRTLRETV-TINYRDFSQLDYELHSLILSGANNPFFSQSLEIITVIFHFqYQWDESDLKERN 255
Cdd:COG1802   102 ERATPADL----ARLRALLEELEAAAaAGDVAAYLELDREFHRALVEAAGNPRLAELLRRLRARLRR-YRRLSLRSPGRL 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1539065270 256 VLAIEEHMTILSALISRNDIVAMNELRHHLDTAKRTMINSIQQ 298
Cdd:COG1802   177 EESLAEHRAILDALEAGDAEAAAAALRAHLERARERLLEALAA 219
HTH_ARSR super family cl46857
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 13-61 7.40e-06

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


The actual alignment was detected with superfamily member cd07377:

Pssm-ID: 481197 [Multi-domain]  Cd Length: 66  Bit Score: 42.82  E-value: 7.40e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1539065270  13 NEFLDAIHKNLLT--SPFPSQSSLAEMFNISRTTVRHTLEYLLEKKIIEKQ 61
Cdd:cd07377     8 DQLREAILSGELKpgDRLPSERELAEELGVSRTTVREALRELEAEGLVERR 58
 
Name Accession Description Interval E-value
GntR COG1802
DNA-binding transcriptional regulator, GntR family [Transcription];
97-298 1.77e-27

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441407 [Multi-domain]  Cd Length: 222  Bit Score: 106.16  E-value: 1.77e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270  97 QMIKRKELMPGDTFTELQLAKKSHVSSSVVREFLVEFSRYGLIKNTHRGNWHMMKFSREYAEKLFEFRELLETNALTHFL 176
Cdd:COG1802    22 EAILSGELPPGERLSEAELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAPLSPEEIRELYEVRAALEGLAARLAA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270 177 NLPADDHRwilaKELLLKHRTLRETV-TINYRDFSQLDYELHSLILSGANNPFFSQSLEIITVIFHFqYQWDESDLKERN 255
Cdd:COG1802   102 ERATPADL----ARLRALLEELEAAAaAGDVAAYLELDREFHRALVEAAGNPRLAELLRRLRARLRR-YRRLSLRSPGRL 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1539065270 256 VLAIEEHMTILSALISRNDIVAMNELRHHLDTAKRTMINSIQQ 298
Cdd:COG1802   177 EESLAEHRAILDALEAGDAEAAAAALRAHLERARERLLEALAA 219
FCD smart00895
This entry represents the C-terminal ligand binding domain of many members of the GntR family; ...
 160-286 1.20e-09

This entry represents the C-terminal ligand binding domain of many members of the GntR family; This domain probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N-terminal DNA-binding domain. This domain is found in and that are regulators of sugar biosynthesis operons. Many bacterial transcription regulation proteins bind DNA through a helix-turn-helix (HTH) motif, which can be classified into subfamilies on the basis of sequence similarities. The HTH GntR family has many members distributed among diverse bacterial groups that regulate various biological processes. It was named GntR after the Bacillus subtilis repressor of the gluconate operon. In general, these proteins contain a DNA-binding HTH domain at the N terminus, and an effector binding or oligomerisation domain at the C terminus. The winged-helix DNA-binding domain is well conserved in structure for the whole of the GntR family, and is similar in structure to other transcriptional regulator families. The C-terminal effector-binding and oligomerisation domains are more variable and are consequently used to define the subfamilies. Based on the sequence and structure of the C-terminal domains, the GtnR family can be divided into four major groups, as represented by FadR, HutC, MocR and YtrA, as well as some minor groups such as those represented by AraR and PlmA.


Pssm-ID: 214892 [Multi-domain]  Cd Length: 123  Bit Score: 55.06  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270  160 LFEFRELLETNALTHFLnLPADDHRWILAKELLLKHRTLRETVTiNYRDFSQLDYELHSLILSGANNPFFSQSLEIITVI 239
Cdd:smart00895   2 LYEVRRALEPLAARLAA-ERATDEDLAALEALLDAMEAAAAAGD-DLEEFAELDREFHRALAEAAGNPVLLELLESLRAR 79

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1539065270  240 FHFQYQWDEsdlkERNVLAIEEHMTILSALISRNDIVAMNELRHHLD 286
Cdd:smart00895  80 LRRLRRLSL----EAARRALDEHRAILDAIRARDAEAARAAMREHLE 122
FCD pfam07729
FCD domain; This domain is the C-terminal ligand binding domain of many members of the GntR ...
 160-273 1.43e-08

FCD domain; This domain is the C-terminal ligand binding domain of many members of the GntR family. This domain binds to a range of effector molecules, including Lactate, Zn(II), Ni(II), Ca(II), Mg(II), citrate, sugar acids, sialic acid and N-acetylglucosamine-6-P, that regulate the transcription of genes through the action of the N-terminal DNA-binding domain pfam00392 (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). This domain is found in Swiss:P45427 and Swiss:P31460 that are regulators of sugar biosynthesis operons. It is also in the known structure of FadR where it binds to acyl-coA, the domain is alpha helical. This family has been named as FCD for (FadR C-terminal Domain).


Pssm-ID: 429623 [Multi-domain]  Cd Length: 121  Bit Score: 51.99  E-value: 1.43e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270 160 LFEFRELLETNAL-THFLNLPADDHRWIlaKELLLKHRTLRETvtINYRDFSQLDYELHSLILSGANNPFFSQSLEIITV 238
Cdd:pfam07729   2 LYELRAALEPLAArLAAERATDEDLAEL--EALLEALEAAADA--GDLEAFAEADREFHLALAEAAGNPVLARMLESLWD 77

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1539065270 239 IFHfQYQWDESDLKERNVLAIEEHMTILSALISRN 273
Cdd:pfam07729  78 RLR-RLRRLLLSSPGRLRASLEEHRAILDAIRARD 111
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 13-61 7.40e-06

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 42.82  E-value: 7.40e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1539065270  13 NEFLDAIHKNLLT--SPFPSQSSLAEMFNISRTTVRHTLEYLLEKKIIEKQ 61
Cdd:cd07377     8 DQLREAILSGELKpgDRLPSERELAEELGVSRTTVREALRELEAEGLVERR 58
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
29-67 2.92e-04

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 38.32  E-value: 2.92e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1539065270   29 PSQSSLAEMFNISRTTVRHTLEYLLEKKIIE-KQGNDYHV 67
Cdd:smart00345  21 PSERELAAQLGVSRTTVREALSRLEAEGLVQrRPGSGTFV 60
MngR COG2188
DNA-binding transcriptional regulator, GntR family [Transcription];
13-61 5.21e-04

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441791 [Multi-domain]  Cd Length: 238  Bit Score: 40.62  E-value: 5.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1539065270  13 NEFLDAIHKNLLT--SPFPSQSSLAEMFNISRTTVRHTLEYLLEKKIIEKQ 61
Cdd:COG2188    12 DALRERIESGELPpgDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERR 62
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 26-63 5.26e-03

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 34.90  E-value: 5.26e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1539065270  26 SPFPSQSSLAEMFNISRTTVRHTLEYLLEKKIIE-KQGN 63
Cdd:pfam00392  22 DKLPSERELAAEFGVSRTTVREALRRLEAEGLVErRQGR 60
PRK09764 PRK09764
GntR family transcriptional regulator;
29-67 6.06e-03

GntR family transcriptional regulator;


Pssm-ID: 182065 [Multi-domain]  Cd Length: 240  Bit Score: 37.50  E-value: 6.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1539065270  29 PSQSSLAEMFNISRTTVRHTLEYLLEKKIIEK-QGNDYHV 67
Cdd:PRK09764   30 PTESALQTEFGVSRVTVRQALRQLVEQQILESiQGSGTYV 69
 
Name Accession Description Interval E-value
GntR COG1802
DNA-binding transcriptional regulator, GntR family [Transcription];
97-298 1.77e-27

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441407 [Multi-domain]  Cd Length: 222  Bit Score: 106.16  E-value: 1.77e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270  97 QMIKRKELMPGDTFTELQLAKKSHVSSSVVREFLVEFSRYGLIKNTHRGNWHMMKFSREYAEKLFEFRELLETNALTHFL 176
Cdd:COG1802    22 EAILSGELPPGERLSEAELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAPLSPEEIRELYEVRAALEGLAARLAA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270 177 NLPADDHRwilaKELLLKHRTLRETV-TINYRDFSQLDYELHSLILSGANNPFFSQSLEIITVIFHFqYQWDESDLKERN 255
Cdd:COG1802   102 ERATPADL----ARLRALLEELEAAAaAGDVAAYLELDREFHRALVEAAGNPRLAELLRRLRARLRR-YRRLSLRSPGRL 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1539065270 256 VLAIEEHMTILSALISRNDIVAMNELRHHLDTAKRTMINSIQQ 298
Cdd:COG1802   177 EESLAEHRAILDALEAGDAEAAAAALRAHLERARERLLEALAA 219
FadR COG2186
DNA-binding transcriptional regulator, FadR family [Transcription];
97-292 2.00e-18

DNA-binding transcriptional regulator, FadR family [Transcription];


Pssm-ID: 441789 [Multi-domain]  Cd Length: 232  Bit Score: 82.29  E-value: 2.00e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270  97 QMIKRKELMPGDTF-TELQLAKKSHVSSSVVREFLVEFSRYGLIKnTHRG---------NWHM-------MKFSREYAEK 159
Cdd:COG2186    18 ELILSGELKPGDRLpSERELAEQLGVSRTTVREALRALEALGLVE-VRQGggtfvrepsPWALldplallLALDDASLRD 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270 160 LFEFRELLETNALTH-FLNLPADDHRWIlaKELLlkhrTLRETVTINYRDFSQLDYELHSLILSGANNPFFSQSLEIITV 238
Cdd:COG2186    97 LLEARLALEPEAARLaAERATDEDLARL--EAAL----AEMEAAADDGEAFAEADLAFHRAIAEASGNPLLALLLESLRE 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1539065270 239 IFHfQYQWDESDLKERNVLAIEEHMTILSALISRNDIVAMNELRHHLDTAKRTM 292
Cdd:COG2186   171 LLR-RSVRLTLRSPEARERSLAEHRAILDAIRAGDPEAARAAMRAHLEAVRERL 223
FCD smart00895
This entry represents the C-terminal ligand binding domain of many members of the GntR family; ...
 160-286 1.20e-09

This entry represents the C-terminal ligand binding domain of many members of the GntR family; This domain probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N-terminal DNA-binding domain. This domain is found in and that are regulators of sugar biosynthesis operons. Many bacterial transcription regulation proteins bind DNA through a helix-turn-helix (HTH) motif, which can be classified into subfamilies on the basis of sequence similarities. The HTH GntR family has many members distributed among diverse bacterial groups that regulate various biological processes. It was named GntR after the Bacillus subtilis repressor of the gluconate operon. In general, these proteins contain a DNA-binding HTH domain at the N terminus, and an effector binding or oligomerisation domain at the C terminus. The winged-helix DNA-binding domain is well conserved in structure for the whole of the GntR family, and is similar in structure to other transcriptional regulator families. The C-terminal effector-binding and oligomerisation domains are more variable and are consequently used to define the subfamilies. Based on the sequence and structure of the C-terminal domains, the GtnR family can be divided into four major groups, as represented by FadR, HutC, MocR and YtrA, as well as some minor groups such as those represented by AraR and PlmA.


Pssm-ID: 214892 [Multi-domain]  Cd Length: 123  Bit Score: 55.06  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270  160 LFEFRELLETNALTHFLnLPADDHRWILAKELLLKHRTLRETVTiNYRDFSQLDYELHSLILSGANNPFFSQSLEIITVI 239
Cdd:smart00895   2 LYEVRRALEPLAARLAA-ERATDEDLAALEALLDAMEAAAAAGD-DLEEFAELDREFHRALAEAAGNPVLLELLESLRAR 79

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1539065270  240 FHFQYQWDEsdlkERNVLAIEEHMTILSALISRNDIVAMNELRHHLD 286
Cdd:smart00895  80 LRRLRRLSL----EAARRALDEHRAILDAIRARDAEAARAAMREHLE 122
FCD pfam07729
FCD domain; This domain is the C-terminal ligand binding domain of many members of the GntR ...
 160-273 1.43e-08

FCD domain; This domain is the C-terminal ligand binding domain of many members of the GntR family. This domain binds to a range of effector molecules, including Lactate, Zn(II), Ni(II), Ca(II), Mg(II), citrate, sugar acids, sialic acid and N-acetylglucosamine-6-P, that regulate the transcription of genes through the action of the N-terminal DNA-binding domain pfam00392 (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). This domain is found in Swiss:P45427 and Swiss:P31460 that are regulators of sugar biosynthesis operons. It is also in the known structure of FadR where it binds to acyl-coA, the domain is alpha helical. This family has been named as FCD for (FadR C-terminal Domain).


Pssm-ID: 429623 [Multi-domain]  Cd Length: 121  Bit Score: 51.99  E-value: 1.43e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539065270 160 LFEFRELLETNAL-THFLNLPADDHRWIlaKELLLKHRTLRETvtINYRDFSQLDYELHSLILSGANNPFFSQSLEIITV 238
Cdd:pfam07729   2 LYELRAALEPLAArLAAERATDEDLAEL--EALLEALEAAADA--GDLEAFAEADREFHLALAEAAGNPVLARMLESLWD 77

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1539065270 239 IFHfQYQWDESDLKERNVLAIEEHMTILSALISRN 273
Cdd:pfam07729  78 RLR-RLRRLLLSSPGRLRASLEEHRAILDAIRARD 111
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 13-61 7.40e-06

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 42.82  E-value: 7.40e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1539065270  13 NEFLDAIHKNLLT--SPFPSQSSLAEMFNISRTTVRHTLEYLLEKKIIEKQ 61
Cdd:cd07377     8 DQLREAILSGELKpgDRLPSERELAEELGVSRTTVREALRELEAEGLVERR 58
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
29-67 2.92e-04

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 38.32  E-value: 2.92e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1539065270   29 PSQSSLAEMFNISRTTVRHTLEYLLEKKIIE-KQGNDYHV 67
Cdd:smart00345  21 PSERELAAQLGVSRTTVREALSRLEAEGLVQrRPGSGTFV 60
MngR COG2188
DNA-binding transcriptional regulator, GntR family [Transcription];
13-61 5.21e-04

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441791 [Multi-domain]  Cd Length: 238  Bit Score: 40.62  E-value: 5.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1539065270  13 NEFLDAIHKNLLT--SPFPSQSSLAEMFNISRTTVRHTLEYLLEKKIIEKQ 61
Cdd:COG2188    12 DALRERIESGELPpgDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERR 62
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 26-63 5.26e-03

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 34.90  E-value: 5.26e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1539065270  26 SPFPSQSSLAEMFNISRTTVRHTLEYLLEKKIIE-KQGN 63
Cdd:pfam00392  22 DKLPSERELAAEFGVSRTTVREALRRLEAEGLVErRQGR 60
PRK09764 PRK09764
GntR family transcriptional regulator;
29-67 6.06e-03

GntR family transcriptional regulator;


Pssm-ID: 182065 [Multi-domain]  Cd Length: 240  Bit Score: 37.50  E-value: 6.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1539065270  29 PSQSSLAEMFNISRTTVRHTLEYLLEKKIIEK-QGNDYHV 67
Cdd:PRK09764   30 PTESALQTEFGVSRVTVRQALRQLVEQQILESiQGSGTYV 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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