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Conserved domains on  [gi|1532594780|ref|WP_125124556|]
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MULTISPECIES: EAL domain-containing protein [Phytobacter]

Protein Classification

EAL domain-containing protein( domain architecture ID 11471819)

EAL domain-containing protein may act as a cyclic diguanylate phosphodiesterase, similar to Escherichia coli putative cyclic-di-GMP phosphodiesterases YjcC and YlaB

Gene Ontology:  GO:0007165

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 1-525 5.13e-173

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


:

Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 498.67  E-value: 5.13e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780   1 MPLQILRTLHHRIGIYALSIVLTFGALYGAGLGVYYIYAHEKLEDYAESILARSNSLISQVKLIdgLRQEFAV-YEPCSA 79
Cdd:COG4943     1 MRMRRRRLLSLATLLALLAALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSA--LDELNALpGDPCSP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  80 QYQQALRKRLWPYPLIKDIAYVEDEKIVCSAlWGKLNAPLSLNMFRNKVNRGSYTWVF-DAQIEENITADVFYTSNFAIT 158
Cdd:COG4943    79 AHLAALRRLVFSSRYVRDIGYVRDGRLLCSS-LGKLSKPVPLPPPDYVTADGYRLWLNvDNPLDPGRPMLIVGRGNYVVV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 159 VSPFAFQRFWEEANkmDFDAIIGDFKHENHFFMIGKNTHLLESIEHNKAHSWL----YFTEHACNNTNDICVIAGTSLPL 234
Cdd:COG4943   158 IDPAAFIDVLSPQP--GISLALLATNGGHLFASSGNPDPALLSRLLRGPSSWFiqgdRLYASACSPQYPICVVAAAPLAG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 235 FFKNNLYILISLFSASLIIGLLIGALYVNNVSHKESLLSRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIG 314
Cdd:COG4943   236 LLALWRQLLLLLLPLGLLLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDPDGS 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 315 RIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPILL-NSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEI 393
Cdd:COG4943   316 VISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDLLAaDPDFHISINLSASDLLSPRFLDDLERLLARTGVAPQQIVLEI 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 394 TERQSSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPK 473
Cdd:COG4943   396 TERGFIDPAKARAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAKTLNL 475

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1532594780 474 IVVFEGVETDIQYQFLKDNVPgGCAQGWYFAKAVPLSELRSVLTDPCGSLPA 525
Cdd:COG4943   476 DVVAEGVETEEQADYLRARGV-QYGQGWLFAKPLPAEEFIAWLAAQRAPASA 526
 
Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 1-525 5.13e-173

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 498.67  E-value: 5.13e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780   1 MPLQILRTLHHRIGIYALSIVLTFGALYGAGLGVYYIYAHEKLEDYAESILARSNSLISQVKLIdgLRQEFAV-YEPCSA 79
Cdd:COG4943     1 MRMRRRRLLSLATLLALLAALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSA--LDELNALpGDPCSP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  80 QYQQALRKRLWPYPLIKDIAYVEDEKIVCSAlWGKLNAPLSLNMFRNKVNRGSYTWVF-DAQIEENITADVFYTSNFAIT 158
Cdd:COG4943    79 AHLAALRRLVFSSRYVRDIGYVRDGRLLCSS-LGKLSKPVPLPPPDYVTADGYRLWLNvDNPLDPGRPMLIVGRGNYVVV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 159 VSPFAFQRFWEEANkmDFDAIIGDFKHENHFFMIGKNTHLLESIEHNKAHSWL----YFTEHACNNTNDICVIAGTSLPL 234
Cdd:COG4943   158 IDPAAFIDVLSPQP--GISLALLATNGGHLFASSGNPDPALLSRLLRGPSSWFiqgdRLYASACSPQYPICVVAAAPLAG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 235 FFKNNLYILISLFSASLIIGLLIGALYVNNVSHKESLLSRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIG 314
Cdd:COG4943   236 LLALWRQLLLLLLPLGLLLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDPDGS 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 315 RIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPILL-NSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEI 393
Cdd:COG4943   316 VISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDLLAaDPDFHISINLSASDLLSPRFLDDLERLLARTGVAPQQIVLEI 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 394 TERQSSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPK 473
Cdd:COG4943   396 TERGFIDPAKARAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAKTLNL 475

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1532594780 474 IVVFEGVETDIQYQFLKDNVPgGCAQGWYFAKAVPLSELRSVLTDPCGSLPA 525
Cdd:COG4943   476 DVVAEGVETEEQADYLRARGV-QYGQGWLFAKPLPAEEFIAWLAAQRAPASA 526
EAL cd01948
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 273-511 7.08e-76

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.


Pssm-ID: 238923 [Multi-domain]  Cd Length: 240  Bit Score: 239.37  E-value: 7.08e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 273 SRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPIL-L 351
Cdd:cd01948     1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQaG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 352 NSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQS-SGTEDIKRSMDLFKGTGIMFALDDFGTGYSNL 430
Cdd:cd01948    81 GPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALiDDLEEALATLRRLRALGVRIALDDFGTGYSSL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 431 NWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQGWYFAKAVP 508
Cdd:cd01948   161 SYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLREL---GCdyVQGYLFSRPLP 237


                  ...
gi 1532594780 509 LSE 511
Cdd:cd01948   238 AEE 240
EAL pfam00563
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 274-506 9.57e-63

EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.


Pssm-ID: 425752 [Multi-domain]  Cd Length: 235  Bit Score: 204.86  E-value: 9.57e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 274 RLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPILLNS 353
Cdd:pfam00563   3 ALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQLGP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 354 DITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQ-SSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNW 432
Cdd:pfam00563  83 DIKLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDlLARLEALREVLKRLRALGIRIALDDFGTGYSSLSY 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1532594780 433 LSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQGWYFAKA 506
Cdd:pfam00563 163 LLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALREL---GCdlVQGYYFSKP 235
EAL smart00052
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ...
 274-509 3.44e-60

Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.


Pssm-ID: 214491 [Multi-domain]  Cd Length: 242  Bit Score: 198.60  E-value: 3.44e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  274 RLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPI--LL 351
Cdd:smart00052   3 ELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWqaQG 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  352 NSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQSSGTEDIKRSM-DLFKGTGIMFALDDFGTGYSNL 430
Cdd:smart00052  83 PPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATlQRLRELGVRIALDDFGTGYSSL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  431 NWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQGWYFAKAVP 508
Cdd:smart00052 163 SYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSL---GCdyGQGYLFSRPLP 239


                   .
gi 1532594780  509 L 509
Cdd:smart00052 240 L 240
PRK11359 PRK11359
cyclic-di-GMP phosphodiesterase; Provisional
 264-512 5.57e-40

cyclic-di-GMP phosphodiesterase; Provisional


Pssm-ID: 183097 [Multi-domain]  Cd Length: 799  Bit Score: 154.54  E-value: 5.57e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 264 NVSHKESLL--SRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEH 341
Cdd:PRK11359  535 NEMVKERLVlgAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAE 614

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 342 SIRECAPI-LLNSDI-TLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQS-SGTEDIKRSMDLFKGTGIMF 418
Cdd:PRK11359  615 ACRQLAEWrSQNIHIpALSVNLSALHFRSNQLPNQVSDAMQAWGIDGHQLTVEITESMMmEHDTEIFKRIQILRDMGVGL 694

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 419 ALDDFGTGYSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC- 497
Cdd:PRK11359  695 SVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKI---HCr 771

                         250
                  ....*....|....*.
gi 1532594780 498 -AQGWYFAKAVPLSEL 512
Cdd:PRK11359  772 vIQGYFFSRPLPAEEI 787
 
Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 1-525 5.13e-173

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 498.67  E-value: 5.13e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780   1 MPLQILRTLHHRIGIYALSIVLTFGALYGAGLGVYYIYAHEKLEDYAESILARSNSLISQVKLIdgLRQEFAV-YEPCSA 79
Cdd:COG4943     1 MRMRRRRLLSLATLLALLAALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSA--LDELNALpGDPCSP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  80 QYQQALRKRLWPYPLIKDIAYVEDEKIVCSAlWGKLNAPLSLNMFRNKVNRGSYTWVF-DAQIEENITADVFYTSNFAIT 158
Cdd:COG4943    79 AHLAALRRLVFSSRYVRDIGYVRDGRLLCSS-LGKLSKPVPLPPPDYVTADGYRLWLNvDNPLDPGRPMLIVGRGNYVVV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 159 VSPFAFQRFWEEANkmDFDAIIGDFKHENHFFMIGKNTHLLESIEHNKAHSWL----YFTEHACNNTNDICVIAGTSLPL 234
Cdd:COG4943   158 IDPAAFIDVLSPQP--GISLALLATNGGHLFASSGNPDPALLSRLLRGPSSWFiqgdRLYASACSPQYPICVVAAAPLAG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 235 FFKNNLYILISLFSASLIIGLLIGALYVNNVSHKESLLSRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIG 314
Cdd:COG4943   236 LLALWRQLLLLLLPLGLLLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDPDGS 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 315 RIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPILL-NSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEI 393
Cdd:COG4943   316 VISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDLLAaDPDFHISINLSASDLLSPRFLDDLERLLARTGVAPQQIVLEI 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 394 TERQSSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPK 473
Cdd:COG4943   396 TERGFIDPAKARAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAKTLNL 475

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1532594780 474 IVVFEGVETDIQYQFLKDNVPgGCAQGWYFAKAVPLSELRSVLTDPCGSLPA 525
Cdd:COG4943   476 DVVAEGVETEEQADYLRARGV-QYGQGWLFAKPLPAEEFIAWLAAQRAPASA 526
EAL cd01948
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 273-511 7.08e-76

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.


Pssm-ID: 238923 [Multi-domain]  Cd Length: 240  Bit Score: 239.37  E-value: 7.08e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 273 SRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPIL-L 351
Cdd:cd01948     1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQaG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 352 NSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQS-SGTEDIKRSMDLFKGTGIMFALDDFGTGYSNL 430
Cdd:cd01948    81 GPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALiDDLEEALATLRRLRALGVRIALDDFGTGYSSL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 431 NWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQGWYFAKAVP 508
Cdd:cd01948   161 SYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLREL---GCdyVQGYLFSRPLP 237


                  ...
gi 1532594780 509 LSE 511
Cdd:cd01948   238 AEE 240
EAL COG2200
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ...
 265-516 2.08e-73

EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms];


Pssm-ID: 441802 [Multi-domain]  Cd Length: 576  Bit Score: 243.54  E-value: 2.08e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 265 VSHKESLLSRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIR 344
Cdd:COG2200   323 ARRRLALESELREALEEGELRLYYQPIVDLRTGRVVGYEALLRWRHPDGGLISPAEFIPAAERSGLIVELDRWVLERALR 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 345 ECAPI-LLNSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQS-SGTEDIKRSMDLFKGTGIMFALDD 422
Cdd:COG2200   403 QLARWpERGLDLRLSVNLSARSLLDPDFLERLLELLAEYGLPPERLVLEITESALlEDLEAAIELLARLRALGVRIALDD 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 423 FGTGYSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQG 500
Cdd:COG2200   483 FGTGYSSLSYLKRLPPDYLKIDRSFVRDIARDPRDQAIVRAIVALAHRLGLKVVAEGVETEEQLEALREL---GCdyAQG 559

                         250
                  ....*....|....*.
gi 1532594780 501 WYFAKAVPLSELRSVL 516
Cdd:COG2200   560 YLFGRPLPLEELEALL 575
COG5001 COG5001
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ...
 270-518 1.84e-71

Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];


Pssm-ID: 444025 [Multi-domain]  Cd Length: 678  Bit Score: 240.83  E-value: 1.84e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 270 SLLSRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECA-- 347
Cdd:COG5001   425 ELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRWQHPERGLVSPAEFIPLAEETGLIVPLGEWVLREACRQLAaw 504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 348 PILLNSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQ-SSGTEDIKRSMDLFKGTGIMFALDDFGTG 426
Cdd:COG5001   505 QDAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITESAlLEDPEEALETLRALRALGVRIALDDFGTG 584

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 427 YSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQGWYFA 504
Cdd:COG5001   585 YSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVETEEQLEFLREL---GCdyAQGYLFS 661

                         250
                  ....*....|....
gi 1532594780 505 KAVPLSELRSVLTD 518
Cdd:COG5001   662 RPLPAEELEALLRA 675
EAL pfam00563
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 274-506 9.57e-63

EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.


Pssm-ID: 425752 [Multi-domain]  Cd Length: 235  Bit Score: 204.86  E-value: 9.57e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 274 RLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPILLNS 353
Cdd:pfam00563   3 ALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQLGP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 354 DITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQ-SSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNW 432
Cdd:pfam00563  83 DIKLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDlLARLEALREVLKRLRALGIRIALDDFGTGYSSLSY 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1532594780 433 LSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQGWYFAKA 506
Cdd:pfam00563 163 LLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALREL---GCdlVQGYYFSKP 235
EAL smart00052
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ...
 274-509 3.44e-60

Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.


Pssm-ID: 214491 [Multi-domain]  Cd Length: 242  Bit Score: 198.60  E-value: 3.44e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  274 RLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPI--LL 351
Cdd:smart00052   3 ELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWqaQG 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  352 NSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQSSGTEDIKRSM-DLFKGTGIMFALDDFGTGYSNL 430
Cdd:smart00052  83 PPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATlQRLRELGVRIALDDFGTGYSSL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  431 NWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC--AQGWYFAKAVP 508
Cdd:smart00052 163 SYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSL---GCdyGQGYLFSRPLP 239


                   .
gi 1532594780  509 L 509
Cdd:smart00052 240 L 240
PRK11359 PRK11359
cyclic-di-GMP phosphodiesterase; Provisional
 264-512 5.57e-40

cyclic-di-GMP phosphodiesterase; Provisional


Pssm-ID: 183097 [Multi-domain]  Cd Length: 799  Bit Score: 154.54  E-value: 5.57e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 264 NVSHKESLL--SRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEH 341
Cdd:PRK11359  535 NEMVKERLVlgAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAE 614

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 342 SIRECAPI-LLNSDI-TLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQS-SGTEDIKRSMDLFKGTGIMF 418
Cdd:PRK11359  615 ACRQLAEWrSQNIHIpALSVNLSALHFRSNQLPNQVSDAMQAWGIDGHQLTVEITESMMmEHDTEIFKRIQILRDMGVGL 694

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 419 ALDDFGTGYSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGC- 497
Cdd:PRK11359  695 SVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKI---HCr 771

                         250
                  ....*....|....*.
gi 1532594780 498 -AQGWYFAKAVPLSEL 512
Cdd:PRK11359  772 vIQGYFFSRPLPAEEI 787
PRK10551 PRK10551
cyclic di-GMP phosphodiesterase;
226-519 4.11e-38

cyclic di-GMP phosphodiesterase;


Pssm-ID: 182541 [Multi-domain]  Cd Length: 518  Bit Score: 146.68  E-value: 4.11e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 226 VIAGTSLPLFFKNNLY----ILISLFsASLIIGLLIGAL----YVNNVSHKESLLSrlkhAIENRELHFVYQPIYRLKDR 297
Cdd:PRK10551  216 TIPGYPLTIRLYADSWtandIWYALL-LGLLSGILVGLLcyylLSLRMRPGKEILT----GIKRGQFYVEYQPVVDTQTL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 298 QVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIREcAPILLNS---DITLSINVSCADICSEEFREK 374
Cdd:PRK10551  291 RVTGLEALLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARD-AAELQKVlpvGAKLGINISPAHLHSDSFKAD 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 375 LLSTLKDENVAGESIILEITERQSSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNWLSLLDVGEIKIDKSITDSIGTE 454
Cdd:PRK10551  370 VQRLLASLPADHFQIVLEITERDMVQEEEATKLFAWLHSQGIEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTE 449

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1532594780 455 STNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNvpgGCA--QGWYFAKAVPLSELRSVLTDP 519
Cdd:PRK10551  450 TVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLRER---GVNflQGYWISRPLPLEDFVRWLKEP 513
PRK11829 PRK11829
biofilm formation regulator HmsP; Provisional
 275-512 3.28e-33

biofilm formation regulator HmsP; Provisional


Pssm-ID: 183329 [Multi-domain]  Cd Length: 660  Bit Score: 133.91  E-value: 3.28e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 275 LKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRecapILLN-- 352
Cdd:PRK11829  410 LLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEEEGMMVPLGNWVLEEACR----ILADwk 485

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 353 ---SDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITErqSSGTEDIKRSMDL---FKGTGIMFALDDFGTG 426
Cdd:PRK11829  486 argVSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITE--TAQIQDLDEALRLlreLQGLGLLIALDDFGIG 563

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 427 YSNLNWL---SLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKnipKIVVFEGVETDIQYQFLKDNvpgG--CAQGW 501
Cdd:PRK11829  564 YSSLRYLnhlKSLPIHMIKLDKSFVKNLPEDDAIARIISCVSDVLK---VRVMAEGVETEEQRQWLLEH---GiqCGQGF 637

                         250
                  ....*....|.
gi 1532594780 502 YFAKAVPLSEL 512
Cdd:PRK11829  638 LFSPPLPRAEF 648
PRK13561 PRK13561
putative diguanylate cyclase; Provisional
 273-511 4.54e-30

putative diguanylate cyclase; Provisional


Pssm-ID: 184143 [Multi-domain]  Cd Length: 651  Bit Score: 124.44  E-value: 4.54e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 273 SRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAP---- 348
Cdd:PRK13561  403 SDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPEGLIDRIESCGLMVTVGHWVLEESCRLLAAwqer 482

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 349 -ILLnsdiTLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQSSGteDIKRSMDLFKG---TGIMFALDDFG 424
Cdd:PRK13561  483 gIML----PLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRID--DPHAAVAILRPlrnAGVRVALDDFG 556

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 425 TGYSNLNWLS---LLDVGEIKIDKSITDSIGTESTnkdILPGLIEMFKNIPKIVVFEGVETDIQYQFLKdNVPGGCAQGW 501
Cdd:PRK13561  557 MGYAGLRQLQhmkSLPIDVLKIDKMFVDGLPEDDS---MVAAIIMLAQSLNLQVIAEGVETEAQRDWLL-KAGVGIAQGF 632

                         250
                  ....*....|
gi 1532594780 502 YFAKAVPLSE 511
Cdd:PRK13561  633 LFARALPIEI 642
PRK10060 PRK10060
cyclic di-GMP phosphodiesterase;
275-508 1.94e-25

cyclic di-GMP phosphodiesterase;


Pssm-ID: 236645 [Multi-domain]  Cd Length: 663  Bit Score: 110.54  E-value: 1.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 275 LKHAIENRELHFVYQPIYRLKDRqVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAP-----I 349
Cdd:PRK10060  413 LRKALENDQLVIHYQPKITWRGE-VRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVMLDVVRQVAKwrdkgI 491

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 350 llnsDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITErqSSGTEDIKRSMDL---FKGTGIMFALDDFGTG 426
Cdd:PRK10060  492 ----NLRVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTE--SCLIENEELALSViqqFSQLGAQVHLDDFGTG 565

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 427 YSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNVPGGcAQGWYFAKA 506
Cdd:PRK10060  566 YSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKEDAFLTKNGVNE-RQGFLFAKP 644


                  ..
gi 1532594780 507 VP 508
Cdd:PRK10060  645 MP 646
CSS-motif pfam12792
CSS motif domain associated with EAL; This family with its characteriztic highly conserved CSS ...
 41-243 1.93e-16

CSS motif domain associated with EAL; This family with its characteriztic highly conserved CSS sequence motif is found N-terminal to the EAL, pfam00563, domain in many cyclic diguanylate phosphodiesterases.


Pssm-ID: 463709  Cd Length: 209  Bit Score: 77.95  E-value: 1.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  41 EKLEDYAESILARSNSLISQVKLIDGLRQEFAVyEPCSAQYQQALRKRLWPYPLIKDIAYVEDEKIVCSALWGKLNAPLS 120
Cdd:pfam12792   3 EQLDAFAERALRRLESVLDQADQALDRLLPLTG-QPCSPAHLAELRRIVAFSPYVRDVGLVKNGRLYCSSLWGELDTPLP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 121 LNMFRNKVNRGSYTWVF-DAQIEENITADVFYTSNFAITVSPFAFqrfweeankMDFDAIIG-----DFKHENHFFMIGK 194
Cdd:pfam12792  82 LLPPDLTTPPGVRLWLLrGTPLVPGRPALVLRRGGYGVVIDPGVF---------IDVQYLPGllaavSQPDGRLLALVVG 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1532594780 195 NTHL-----LESIEHNKAHSWL---YFTEHACNNTNDICVIAGTSLPLFFKNNLYIL 243
Cdd:pfam12792 153 DDALlfdgrLHSLAEPAPGTARsggALYARARSTRYPLTVVVYAPRASLLANWRQLL 209
PRK09776 PRK09776
putative diguanylate cyclase; Provisional
 266-446 1.04e-11

putative diguanylate cyclase; Provisional


Pssm-ID: 182070 [Multi-domain]  Cd Length: 1092  Bit Score: 67.78  E-value: 1.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  266 SHKE-SLLSRLKHAIENRELHFVYQPIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIR 344
Cdd:PRK09776   836 EHRAlSLAEQWRMIKENQLMMLAHGVASPRIPEARNHWLISLRLWDPEGEIIDEGAFRPAAEDPALMHALDRRVIHEFFR 915

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780  345 ECAPILLNSDITLSINVSCADICSEEFREKLLSTLKDENVAGESIILEITERQ-SSGTEDIKRSMDLFKGTGIMFALDDF 423
Cdd:PRK09776   916 QAAKAVASKGLSIALPLSVAGLSSPTLLPFLLEQLENSPLPPRLLHLEITETAlLNHAESASRLVQKLRLAGCRVVLSDF 995

                          170       180
                   ....*....|....*....|...
gi 1532594780  424 GTGYSNLNWLSLLDVGEIKIDKS 446
Cdd:PRK09776   996 GRGLSSFNYLKAFMADYLKLDGE 1018
PRK11059 PRK11059
regulatory protein CsrD; Provisional
 275-509 1.08e-07

regulatory protein CsrD; Provisional


Pssm-ID: 236833 [Multi-domain]  Cd Length: 640  Bit Score: 54.48  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 275 LKHAIENRELHFVYQPIYrLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIrecAPILLNSD 354
Cdd:PRK11059  408 LEQTLVRGGPRLYQQPAV-TRDGKVHHRELFCRIRDGQGELLSAELFMPMVQQLGLSEQYDRQVIERVL---PLLRYWPE 483

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 355 ITLSINVSCADICSEEF----REKLLSTLKDENvagESIILEITERQ-SSGTEDIKRSMDLFKGTGIMFALDDFG----- 424
Cdd:PRK11059  484 ENLSINLSVDSLLSRAFqrwlRDTLLQCPRSQR---KRLIFELAEADvCQHISRLRPVLRMLRGLGCRLAVDQAGltvvs 560

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 425 TGYsnlnwLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDN-VPGGcaQGWYF 503
Cdd:PRK11059  561 TSY-----IKELNVELIKLHPSLVRNIHKRTENQLFVRSLVGACAGTETQVFATGVESREEWQTLQELgVSGG--QGDFF 633


                  ....*.
gi 1532594780 504 AKAVPL 509
Cdd:PRK11059  634 AESQPL 639
PRK11596 PRK11596
cyclic-di-GMP phosphodiesterase; Provisional
 420-515 1.20e-07

cyclic-di-GMP phosphodiesterase; Provisional


Pssm-ID: 183222 [Multi-domain]  Cd Length: 255  Bit Score: 53.08  E-value: 1.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 420 LDDFGTGYSNLNWLSLLDVGEIKIDKSITDSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKdNVPGGCAQ 499
Cdd:PRK11596  157 LDDFGTGMANFSALSEVRYDYIKVARELFIMLRQSEEGRNLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQ-RSPAFAAQ 235

                          90
                  ....*....|....*.
gi 1532594780 500 GWYFAKAVPLSELRSV 515
Cdd:PRK11596  236 GYFLSRPAPFETLETL 251
YuxH COG3434
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction ...
 387-510 7.08e-07

c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction mechanisms];


Pssm-ID: 442660 [Multi-domain]  Cd Length: 407  Bit Score: 51.73  E-value: 7.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1532594780 387 ESIILEITERqSSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNWLSLLDVgeIKIDksitdsigTESTNKDILPGLIE 466
Cdd:COG3434    84 ERVVLEILED-VEPDEELLEALKELKEKGYRIALDDFVLDPEWDPLLPLADI--IKID--------VLALDLEELAELVA 152

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1532594780 467 MFKNIPKIVVFEGVETDIQYQFLKDNvpgGCA--QGWYFAKAVPLS 510
Cdd:COG3434   153 RLKRYGIKLLAEKVETREEFELCKEL---GFDlfQGYFFSKPEILK 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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