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Conserved domains on  [gi|1480993443|ref|WP_119629988|]
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translation elongation factor Ts [Methylocaldum marinum]

Protein Classification

translation elongation factor Ts( domain architecture ID 11415728)

translation elongation factor Ts associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP

CATH:  3.30.479.20
Gene Ontology:  GO:0003746|GO:0006414

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Tsf COG0264
Translation elongation factor EF-Ts [Translation, ribosomal structure and biogenesis]; ...
1-293 4.34e-163

Translation elongation factor EF-Ts [Translation, ribosomal structure and biogenesis]; Translation elongation factor EF-Ts is part of the Pathway/BioSystem: Translation factors


:

Pssm-ID: 440034 [Multi-domain]  Cd Length: 290  Bit Score: 454.53  E-value: 4.34e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   1 MNISAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTsaDGKRAVILEINCE 80
Cdd:COG0264     1 AAITAALVKELRERTGAGMMDCKKALTEADGDIEKAIEILRKKGLAKAAKKAGRVAAEGLVAVAV--DGKKGAIVEVNCE 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  81 TDFVAKGDDFTDFADKVVETALDSTAGSLEDLFATMIPstGSSVEETRRAMIAKIGENINVRRFESITSErGIVASYLH- 159
Cdd:COG0264    79 TDFVAKNEDFQAFANEVAEAALAAKPADVEALLAAPLD--GKTVEEAITELIAKIGENISLRRFARLEVG-GVVGSYVHn 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 160 GTRIGVLVELIG-GDQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEV 238
Cdd:COG0264   156 GGKIGVLVALEGdADEELAKDIAMHIAAMNPKYLSREDVPAEVVEKEREIATEQAREEGKPENIIEKIVEGRLNKFLKEV 235
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1480993443 239 TLLGQPFVKDPDQTVGKLLSSRGASVGRFVRFEVGEGIEKAESNFAEEVMAQVRN 293
Cdd:COG0264   236 TLLEQPFVKDPKKTVGQLLKEAGAKVVGFVRFEVGEGIEKKEEDFAAEVAAQAKG 290
 
Name Accession Description Interval E-value
Tsf COG0264
Translation elongation factor EF-Ts [Translation, ribosomal structure and biogenesis]; ...
1-293 4.34e-163

Translation elongation factor EF-Ts [Translation, ribosomal structure and biogenesis]; Translation elongation factor EF-Ts is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440034 [Multi-domain]  Cd Length: 290  Bit Score: 454.53  E-value: 4.34e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   1 MNISAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTsaDGKRAVILEINCE 80
Cdd:COG0264     1 AAITAALVKELRERTGAGMMDCKKALTEADGDIEKAIEILRKKGLAKAAKKAGRVAAEGLVAVAV--DGKKGAIVEVNCE 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  81 TDFVAKGDDFTDFADKVVETALDSTAGSLEDLFATMIPstGSSVEETRRAMIAKIGENINVRRFESITSErGIVASYLH- 159
Cdd:COG0264    79 TDFVAKNEDFQAFANEVAEAALAAKPADVEALLAAPLD--GKTVEEAITELIAKIGENISLRRFARLEVG-GVVGSYVHn 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 160 GTRIGVLVELIG-GDQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEV 238
Cdd:COG0264   156 GGKIGVLVALEGdADEELAKDIAMHIAAMNPKYLSREDVPAEVVEKEREIATEQAREEGKPENIIEKIVEGRLNKFLKEV 235
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1480993443 239 TLLGQPFVKDPDQTVGKLLSSRGASVGRFVRFEVGEGIEKAESNFAEEVMAQVRN 293
Cdd:COG0264   236 TLLEQPFVKDPKKTVGQLLKEAGAKVVGFVRFEVGEGIEKKEEDFAAEVAAQAKG 290
tsf TIGR00116
translation elongation factor Ts; Translational elongation factor Ts (EF-Ts) catalyzes the ...
1-292 4.11e-110

translation elongation factor Ts; Translational elongation factor Ts (EF-Ts) catalyzes the exchange of GTP for the GDP of the EF-Tu.GDP complex as part of the cycle of translation elongation. This protein is found in Bacteria, mitochondria, and chloroplasts. [Protein synthesis, Translation factors]


Pssm-ID: 272914 [Multi-domain]  Cd Length: 291  Bit Score: 320.57  E-value: 4.11e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   1 MNISAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTsaDGKRAVILEINCE 80
Cdd:TIGR00116   2 MAITAQLVKELRERTGAGMMDCKKALVEANGDFEKAIKWLREKGIAKAAKKADRVAAEGVIVLKS--DNHKAVIVEVNSE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  81 TDFVAKGDDFTDFADKVVETALDSTAGSLEDLFAtmIPSTGSSVEETRRAMIAKIGENINVRRFESITSERGIVASYLH- 159
Cdd:TIGR00116  80 TDFVAKNEGFKEFANKLLDELKANPITTLEELQK--QELENKEKVEYLASLAAKIGENIVLRRVAVLEGQSNVIFSYLHa 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 160 GTRIGVLVELIGG-DQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEV 238
Cdd:TIGR00116 158 NARIGVLVELKGKaDEELAKHLAMHVAANKPQFIDQDDVSQEWVKKERQIITDQAELSGKPKEILEKMVEGRMKKFLAEI 237
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1480993443 239 TLLGQPFVKDPDQTVGKLLSSRGASVGRFVRFEVGEGIEKAESNFAEEVMAQVR 292
Cdd:TIGR00116 238 SLLGQKFVMDPSKTVGQFLKEKNAKVTEFVRFEVGEGIEKKAEDFAEEVAAQMK 291
EF_TS pfam00889
Elongation factor TS;
72-274 6.09e-100

Elongation factor TS;


Pssm-ID: 459984  Cd Length: 204  Bit Score: 291.36  E-value: 6.09e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  72 AVILEINCETDFVAKGDDFTDFADKVVETALDSTAGSLEDLFATMIPStGSSVEETRRAMIAKIGENINVRRFESITSER 151
Cdd:pfam00889   1 AVIVEVNSETDFVAKNEDFQEFVNKIAEAALAAKPADVEELLALKLEG-GETVEDALTELIAKIGENIVLRRFATLEGDG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 152 GIVASYLHGT-RIGVLVELIGG-DQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEG 229
Cdd:pfam00889  80 GVVGSYIHGNgRIGVLVALEGDdDEELAKDIAMHIAAMNPQYLSRDDVPAEVLEKEREILKAQAKEEGKPENIIEKIVEG 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1480993443 230 KIKKFLGEVTLLGQPFVKDPDQTVGKLLSSRGASVGRFVRFEVGE 274
Cdd:pfam00889 160 RLNKFLKEVCLLEQPFVKDPKKTVEQYLKEAGKKVVSFVRFEVGE 204
tsf PRK12332
elongation factor Ts; Reviewed
1-275 2.56e-81

elongation factor Ts; Reviewed


Pssm-ID: 183447 [Multi-domain]  Cd Length: 198  Bit Score: 244.04  E-value: 2.56e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   1 MNISAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTSADGKRAVILEINCE 80
Cdd:PRK12332    1 MAITAKLVKELREKTGAGMMDCKKALEEANGDMEKAIEWLREKGLAKAAKKAGRVAAEGLVGSYIHTGGRIGVLVELNCE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  81 TDFVAKGDDFtdfadkvvetaldstagsledlfatmipstgssveetrramiakigeninvrrfesitsergivasylhg 160
Cdd:PRK12332   81 TDFVARTEEF---------------------------------------------------------------------- 90
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 161 trigvlveliggdQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEVTL 240
Cdd:PRK12332   91 -------------KELAKDIAMQIAAANPEYVSREDVPAEVIEKEKEIYRAQALNEGKPENIVEKIVEGRIEKFYKEVCL 157
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1480993443 241 LGQPFVKDPDQTVGKLLSSRGA------SVGRFVRFEVGEG 275
Cdd:PRK12332  158 LEQPFIKDPSKTVEDLIKEAIAkigeniVVRRFARFELGEG 198
UBA_EF-Ts cd14275
UBA domain found in elongation factor Ts (EF-Ts) from bacteria, chloroplasts and mitochondria ...
6-42 8.50e-15

UBA domain found in elongation factor Ts (EF-Ts) from bacteria, chloroplasts and mitochondria of eukaryotes; EF-Ts functions as a nucleotide exchange factor in the functional cycle of EF-Tu, another translation elongation factor that facilitates the binding of aminoacylated transfer RNAs (aminoacyl-tRNA) to the ribosomal A site as a ternary complex with guanosine triphosphate during the elongation cycle of protein biosynthesis, and then catalyzes the hydrolysis of GTP and release itself in GDP-bound form. EF-Ts forms complex with EF-Tu and catalyzes the nucleotide exchange reaction promoting the formation of EF-Tu in GTP-bound form from EF-Tu in GDP-bound form. EF-Ts from Thermus thermophiles is shorter than EF-Ts from Escherichia coli, but it has higher thermostability. The mitochondrial translational EF-Ts from chloroplasts and mitochondria display high similarity to the bacterial EF-Ts. The majority of family members contain one ubiquitin-associated (UBA) domain, but some family members from plants harbor two tandem UBA domains.


Pssm-ID: 270461 [Multi-domain]  Cd Length: 37  Bit Score: 67.03  E-value: 8.50e-15
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1480993443   6 AMVKELRERTGSGMMECKKALQEASGDMEAAVELMRK 42
Cdd:cd14275     1 ELIKELREKTGAGIMDCKKALEEANGDLEKAIEWLRK 37
 
Name Accession Description Interval E-value
Tsf COG0264
Translation elongation factor EF-Ts [Translation, ribosomal structure and biogenesis]; ...
1-293 4.34e-163

Translation elongation factor EF-Ts [Translation, ribosomal structure and biogenesis]; Translation elongation factor EF-Ts is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440034 [Multi-domain]  Cd Length: 290  Bit Score: 454.53  E-value: 4.34e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   1 MNISAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTsaDGKRAVILEINCE 80
Cdd:COG0264     1 AAITAALVKELRERTGAGMMDCKKALTEADGDIEKAIEILRKKGLAKAAKKAGRVAAEGLVAVAV--DGKKGAIVEVNCE 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  81 TDFVAKGDDFTDFADKVVETALDSTAGSLEDLFATMIPstGSSVEETRRAMIAKIGENINVRRFESITSErGIVASYLH- 159
Cdd:COG0264    79 TDFVAKNEDFQAFANEVAEAALAAKPADVEALLAAPLD--GKTVEEAITELIAKIGENISLRRFARLEVG-GVVGSYVHn 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 160 GTRIGVLVELIG-GDQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEV 238
Cdd:COG0264   156 GGKIGVLVALEGdADEELAKDIAMHIAAMNPKYLSREDVPAEVVEKEREIATEQAREEGKPENIIEKIVEGRLNKFLKEV 235
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1480993443 239 TLLGQPFVKDPDQTVGKLLSSRGASVGRFVRFEVGEGIEKAESNFAEEVMAQVRN 293
Cdd:COG0264   236 TLLEQPFVKDPKKTVGQLLKEAGAKVVGFVRFEVGEGIEKKEEDFAAEVAAQAKG 290
tsf TIGR00116
translation elongation factor Ts; Translational elongation factor Ts (EF-Ts) catalyzes the ...
1-292 4.11e-110

translation elongation factor Ts; Translational elongation factor Ts (EF-Ts) catalyzes the exchange of GTP for the GDP of the EF-Tu.GDP complex as part of the cycle of translation elongation. This protein is found in Bacteria, mitochondria, and chloroplasts. [Protein synthesis, Translation factors]


Pssm-ID: 272914 [Multi-domain]  Cd Length: 291  Bit Score: 320.57  E-value: 4.11e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   1 MNISAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTsaDGKRAVILEINCE 80
Cdd:TIGR00116   2 MAITAQLVKELRERTGAGMMDCKKALVEANGDFEKAIKWLREKGIAKAAKKADRVAAEGVIVLKS--DNHKAVIVEVNSE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  81 TDFVAKGDDFTDFADKVVETALDSTAGSLEDLFAtmIPSTGSSVEETRRAMIAKIGENINVRRFESITSERGIVASYLH- 159
Cdd:TIGR00116  80 TDFVAKNEGFKEFANKLLDELKANPITTLEELQK--QELENKEKVEYLASLAAKIGENIVLRRVAVLEGQSNVIFSYLHa 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 160 GTRIGVLVELIGG-DQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEV 238
Cdd:TIGR00116 158 NARIGVLVELKGKaDEELAKHLAMHVAANKPQFIDQDDVSQEWVKKERQIITDQAELSGKPKEILEKMVEGRMKKFLAEI 237
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1480993443 239 TLLGQPFVKDPDQTVGKLLSSRGASVGRFVRFEVGEGIEKAESNFAEEVMAQVR 292
Cdd:TIGR00116 238 SLLGQKFVMDPSKTVGQFLKEKNAKVTEFVRFEVGEGIEKKAEDFAEEVAAQMK 291
EF_TS pfam00889
Elongation factor TS;
72-274 6.09e-100

Elongation factor TS;


Pssm-ID: 459984  Cd Length: 204  Bit Score: 291.36  E-value: 6.09e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  72 AVILEINCETDFVAKGDDFTDFADKVVETALDSTAGSLEDLFATMIPStGSSVEETRRAMIAKIGENINVRRFESITSER 151
Cdd:pfam00889   1 AVIVEVNSETDFVAKNEDFQEFVNKIAEAALAAKPADVEELLALKLEG-GETVEDALTELIAKIGENIVLRRFATLEGDG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 152 GIVASYLHGT-RIGVLVELIGG-DQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEG 229
Cdd:pfam00889  80 GVVGSYIHGNgRIGVLVALEGDdDEELAKDIAMHIAAMNPQYLSRDDVPAEVLEKEREILKAQAKEEGKPENIIEKIVEG 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1480993443 230 KIKKFLGEVTLLGQPFVKDPDQTVGKLLSSRGASVGRFVRFEVGE 274
Cdd:pfam00889 160 RLNKFLKEVCLLEQPFVKDPKKTVEQYLKEAGKKVVSFVRFEVGE 204
tsf PRK12332
elongation factor Ts; Reviewed
1-275 2.56e-81

elongation factor Ts; Reviewed


Pssm-ID: 183447 [Multi-domain]  Cd Length: 198  Bit Score: 244.04  E-value: 2.56e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   1 MNISAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTSADGKRAVILEINCE 80
Cdd:PRK12332    1 MAITAKLVKELREKTGAGMMDCKKALEEANGDMEKAIEWLREKGLAKAAKKAGRVAAEGLVGSYIHTGGRIGVLVELNCE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  81 TDFVAKGDDFtdfadkvvetaldstagsledlfatmipstgssveetrramiakigeninvrrfesitsergivasylhg 160
Cdd:PRK12332   81 TDFVARTEEF---------------------------------------------------------------------- 90
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 161 trigvlveliggdQALGRDIAMHVAASKPLCVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEVTL 240
Cdd:PRK12332   91 -------------KELAKDIAMQIAAANPEYVSREDVPAEVIEKEKEIYRAQALNEGKPENIVEKIVEGRIEKFYKEVCL 157
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1480993443 241 LGQPFVKDPDQTVGKLLSSRGA------SVGRFVRFEVGEG 275
Cdd:PRK12332  158 LEQPFIKDPSKTVEDLIKEAIAkigeniVVRRFARFELGEG 198
tsf CHL00098
elongation factor Ts
4-278 2.76e-53

elongation factor Ts


Pssm-ID: 214362  Cd Length: 200  Bit Score: 172.56  E-value: 2.76e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443   4 SAAMVKELRERTGSGMMECKKALQEASGDMEAAVELMRKAGLAKADKKSGRTAAEGLISTRTSADGKRAVILEINCETDF 83
Cdd:CHL00098    1 SAELVKELRDKTGAGMMDCKKALQEANGDFEKALESLRQKGLASANKKSTRITTEGLIESYIHTGGKLGVLVEINCETDF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443  84 VAKGDDFTDFAdkvvetaldstagsledlfatmipstgssveetrramiakigeninvrrfesitsergivasylhgtri 163
Cdd:CHL00098   81 VARREEFQKLA--------------------------------------------------------------------- 91
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1480993443 164 gvlveliggdqalgRDIAMHVAASKPL-CVEDKDVPAETVAKEREIAKAQAEAEGKPANIVEKMVEGKIKKFLGEVTLLG 242
Cdd:CHL00098   92 --------------KNIAMQIAACPNVkYVSLEDIPEEIINLEKKIESEKDDLQNKPEEIKEKIVEGRIKKRLKELSLLD 157
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1480993443 243 QPFVKDPDQTVGKLLSSRGASVG------RFVRFEVGEGIEK 278
Cdd:CHL00098  158 QPFIRDQSITVEELIKQNIAKLGeniqirRFARFTLGEGEEK 199
UBA_EF-Ts cd14275
UBA domain found in elongation factor Ts (EF-Ts) from bacteria, chloroplasts and mitochondria ...
6-42 8.50e-15

UBA domain found in elongation factor Ts (EF-Ts) from bacteria, chloroplasts and mitochondria of eukaryotes; EF-Ts functions as a nucleotide exchange factor in the functional cycle of EF-Tu, another translation elongation factor that facilitates the binding of aminoacylated transfer RNAs (aminoacyl-tRNA) to the ribosomal A site as a ternary complex with guanosine triphosphate during the elongation cycle of protein biosynthesis, and then catalyzes the hydrolysis of GTP and release itself in GDP-bound form. EF-Ts forms complex with EF-Tu and catalyzes the nucleotide exchange reaction promoting the formation of EF-Tu in GTP-bound form from EF-Tu in GDP-bound form. EF-Ts from Thermus thermophiles is shorter than EF-Ts from Escherichia coli, but it has higher thermostability. The mitochondrial translational EF-Ts from chloroplasts and mitochondria display high similarity to the bacterial EF-Ts. The majority of family members contain one ubiquitin-associated (UBA) domain, but some family members from plants harbor two tandem UBA domains.


Pssm-ID: 270461 [Multi-domain]  Cd Length: 37  Bit Score: 67.03  E-value: 8.50e-15
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1480993443   6 AMVKELRERTGSGMMECKKALQEASGDMEAAVELMRK 42
Cdd:cd14275     1 ELIKELREKTGAGIMDCKKALEEANGDLEKAIEWLRK 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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