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Conserved domains on  [gi|1474085439|ref|WP_118500097|]
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leucine-rich repeat domain-containing protein [Clostridium sp. AF34-13]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 12134568)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
SCOP:  4003523

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
123-252 1.30e-34

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


:

Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 128.05  E-value: 1.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 123 KTISQYAFKKSrKLTEIVIPDSVSNIGEGAFYGCRSLTNITLPKKVTKIHPYTFYNClSLKNIKLNSSIKRLGYKAFKKC 202
Cdd:pfam13306   1 TSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNC 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1474085439 203 KSLESLTIPKNITKIESETFKECeNLKKVVLPSTLETIAYKAFSNCNSLN 252
Cdd:pfam13306  79 SNLKSITLPSNLTSIGSYAFSNC-SLKSITIPSSVTTIGSYAFSNCSNLK 127
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
215-341 4.62e-32

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


:

Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 121.11  E-value: 4.62e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 215 TKIESETFKECeNLKKVVLPSTLETIAYKAFSNCNSLNTLKLPNGLELIDDYAFYACNsLKSIKLPDNIDKIYDHTFADC 294
Cdd:pfam13306   1 TSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCS-LTSITIPSSLTSIGEYAFSNC 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1474085439 295 KNLSSVYMGKNTTIIGYMAFSGCtSLKNITIPANVESISNTAFDNSI 341
Cdd:pfam13306  79 SNLKSITLPSNLTSIGSYAFSNC-SLKSITIPSSVTTIGSYAFSNCS 124
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
285-433 4.05e-15

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


:

Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 72.58  E-value: 4.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 285 KIYDHTFADCkNLSSVYMGKNTTIIGYMAFSGCTSLKNITIPANVESISNTAFDNSIetfkvssdstkfsasdgilynkn 364
Cdd:pfam13306   2 SIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCS----------------------- 57
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1474085439 365 kttIKKFpclksgnyKMPNTVKKIASNAFTNSESLKNITFSDNIAILYLDDFRNSGINTMHLPAKLEYV 433
Cdd:pfam13306  58 ---LTSI--------TIPSSLTSIGEYAFSNCSNLKSITLPSNLTSIGSYAFSNCSLKSITIPSSVTTI 115
 
Name Accession Description Interval E-value
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
123-252 1.30e-34

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 128.05  E-value: 1.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 123 KTISQYAFKKSrKLTEIVIPDSVSNIGEGAFYGCRSLTNITLPKKVTKIHPYTFYNClSLKNIKLNSSIKRLGYKAFKKC 202
Cdd:pfam13306   1 TSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNC 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1474085439 203 KSLESLTIPKNITKIESETFKECeNLKKVVLPSTLETIAYKAFSNCNSLN 252
Cdd:pfam13306  79 SNLKSITLPSNLTSIGSYAFSNC-SLKSITIPSSVTTIGSYAFSNCSNLK 127
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
215-341 4.62e-32

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 121.11  E-value: 4.62e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 215 TKIESETFKECeNLKKVVLPSTLETIAYKAFSNCNSLNTLKLPNGLELIDDYAFYACNsLKSIKLPDNIDKIYDHTFADC 294
Cdd:pfam13306   1 TSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCS-LTSITIPSSLTSIGEYAFSNC 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1474085439 295 KNLSSVYMGKNTTIIGYMAFSGCtSLKNITIPANVESISNTAFDNSI 341
Cdd:pfam13306  79 SNLKSITLPSNLTSIGSYAFSNC-SLKSITIPSSVTTIGSYAFSNCS 124
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
285-433 4.05e-15

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 72.58  E-value: 4.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 285 KIYDHTFADCkNLSSVYMGKNTTIIGYMAFSGCTSLKNITIPANVESISNTAFDNSIetfkvssdstkfsasdgilynkn 364
Cdd:pfam13306   2 SIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCS----------------------- 57
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1474085439 365 kttIKKFpclksgnyKMPNTVKKIASNAFTNSESLKNITFSDNIAILYLDDFRNSGINTMHLPAKLEYV 433
Cdd:pfam13306  58 ---LTSI--------TIPSSLTSIGEYAFSNCSNLKSITLPSNLTSIGSYAFSNCSLKSITIPSSVTTI 115
 
Name Accession Description Interval E-value
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
123-252 1.30e-34

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 128.05  E-value: 1.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 123 KTISQYAFKKSrKLTEIVIPDSVSNIGEGAFYGCRSLTNITLPKKVTKIHPYTFYNClSLKNIKLNSSIKRLGYKAFKKC 202
Cdd:pfam13306   1 TSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNC 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1474085439 203 KSLESLTIPKNITKIESETFKECeNLKKVVLPSTLETIAYKAFSNCNSLN 252
Cdd:pfam13306  79 SNLKSITLPSNLTSIGSYAFSNC-SLKSITIPSSVTTIGSYAFSNCSNLK 127
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
146-275 1.08e-33

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 125.74  E-value: 1.08e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 146 SNIGEGAFYGCrSLTNITLPKKVTKIHPYTFYNCLSLKNIKLNSSIKRLGYKAFKKCkSLESLTIPKNITKIESETFKEC 225
Cdd:pfam13306   1 TSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNC 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1474085439 226 ENLKKVVLPSTLETIAYKAFSNCNsLNTLKLPNGLELIDDYAFYACNSLK 275
Cdd:pfam13306  79 SNLKSITLPSNLTSIGSYAFSNCS-LKSITIPSSVTTIGSYAFSNCSNLK 127
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
215-341 4.62e-32

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 121.11  E-value: 4.62e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 215 TKIESETFKECeNLKKVVLPSTLETIAYKAFSNCNSLNTLKLPNGLELIDDYAFYACNsLKSIKLPDNIDKIYDHTFADC 294
Cdd:pfam13306   1 TSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCS-LTSITIPSSLTSIGEYAFSNC 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1474085439 295 KNLSSVYMGKNTTIIGYMAFSGCtSLKNITIPANVESISNTAFDNSI 341
Cdd:pfam13306  79 SNLKSITLPSNLTSIGSYAFSNC-SLKSITIPSSVTTIGSYAFSNCS 124
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
117-229 3.39e-29

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 112.64  E-value: 3.39e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 117 TIPAGVKTISQYAFKKSRKLTEIVIPDSVSNIGEGAFYGCrSLTNITLPKKVTKIHPYTFYNCLSLKNIKLNSSIKRLGY 196
Cdd:pfam13306  17 TIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCSNLKSITLPSNLTSIGS 95
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1474085439 197 KAFKKCkSLESLTIPKNITKIESETFKECENLK 229
Cdd:pfam13306  96 YAFSNC-SLKSITIPSSVTTIGSYAFSNCSNLK 127
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
285-433 4.05e-15

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 72.58  E-value: 4.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 285 KIYDHTFADCkNLSSVYMGKNTTIIGYMAFSGCTSLKNITIPANVESISNTAFDNSIetfkvssdstkfsasdgilynkn 364
Cdd:pfam13306   2 SIGSYAFYNC-SLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCS----------------------- 57
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1474085439 365 kttIKKFpclksgnyKMPNTVKKIASNAFTNSESLKNITFSDNIAILYLDDFRNSGINTMHLPAKLEYV 433
Cdd:pfam13306  58 ---LTSI--------TIPSSLTSIGEYAFSNCSNLKSITLPSNLTSIGSYAFSNCSLKSITIPSSVTTI 115
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
115-183 1.44e-14

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 71.04  E-value: 1.44e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1474085439 115 TYTIPAGVKTISQYAFKKSRKLTEIVIPDSVSNIGEGAFYGCrSLTNITLPKKVTKIHPYTFYNCLSLK 183
Cdd:pfam13306  60 SITIPSSLTSIGEYAFSNCSNLKSITLPSNLTSIGSYAFSNC-SLKSITIPSSVTTIGSYAFSNCSNLK 127
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
380-458 1.36e-06

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 47.92  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1474085439 380 KMPNTVKKIASNAFTNSESLKNITFSDNIAILYLDDFRNSGINTMHLPAKLEYVAGNS-SYLKKLTTITIPETNKRFFTY 458
Cdd:pfam13306  17 TIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGEYAfSNCSNLKSITLPSNLTSIGSY 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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