NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1468633221|ref|WP_117508930|]
View 

MULTISPECIES: AAA family ATPase [Lachnospiraceae]

Protein Classification

AAA family ATPase( domain architecture ID 11437845)

AAA family ATPase similar to (d)CMP kinase, which catalyzes the phosphorylation of cytidine monophosphate (CMP) or dCMP to produce cytidine diphosphate (CDP) or dCDP, using ATP as the preferred phosphoryl donor

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
4-204 1.06e-75

Cytidylate kinase [Nucleotide transport and metabolism];


:

Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 225.86  E-value: 1.06e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221   4 IITIGRQYGSAGHSIGKILADDLGIKYYDKELLERAAKDSGLCQELFENHDEKPTNSFLyslvmdsysfgygstmMDMPL 83
Cdd:COG1102     2 VITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKAPSLLY----------------RDTAE 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221  84 NQKVFLAQFDAIKKISQDGPCVIVGRCADYALEENPNVLSIFIKADMQDRIRRIAKLYDLSDAKAKDKITKIDKQRASYY 163
Cdd:COG1102    66 EDEIDRALDKVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYY 145
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1468633221 164 NYYTSKRWGEVDSYDLCLNSSVFGIDGTVDMIKQAIEVKEA 204
Cdd:COG1102   146 KYYYGIDWGDPSNYDLVINTSRLGIEEAVDLILAAIEAREK 186
 
Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
4-204 1.06e-75

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 225.86  E-value: 1.06e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221   4 IITIGRQYGSAGHSIGKILADDLGIKYYDKELLERAAKDSGLCQELFENHDEKPTNSFLyslvmdsysfgygstmMDMPL 83
Cdd:COG1102     2 VITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKAPSLLY----------------RDTAE 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221  84 NQKVFLAQFDAIKKISQDGPCVIVGRCADYALEENPNVLSIFIKADMQDRIRRIAKLYDLSDAKAKDKITKIDKQRASYY 163
Cdd:COG1102    66 EDEIDRALDKVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYY 145
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1468633221 164 NYYTSKRWGEVDSYDLCLNSSVFGIDGTVDMIKQAIEVKEA 204
Cdd:COG1102   146 KYYYGIDWGDPSNYDLVINTSRLGIEEAVDLILAAIEAREK 186
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
4-184 1.70e-70

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 212.49  E-value: 1.70e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221   4 IITIGRQYGSAGHSIGKILADDLGIKYYDKELLERAAKDSGLCQELFENHDEKPT-NSFLYSLVMdsysfgyGSTMMDMP 82
Cdd:pfam13189   1 VITISRQYGSGGTTIAKKLAEKLGYPFYDREILDEIAKELGISEEEFELFDEKSRlSSFLYSLAG-------GRVRGDAL 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221  83 LNQKVFLAQFDAIKKISQDGPCVIVGRCADYALEENPNVLSIFIKADMQDRIRRIAKLYDLSDAKAKDKITKIDKQRASY 162
Cdd:pfam13189  74 SDDRLFDAQSKVIRELAAEDNCVIVGRGADYILKDIPNVLRVFLTAPLEDRVKRVMEREGLSEEEARELIKETDKRRAKY 153
                         170       180
                  ....*....|....*....|..
gi 1468633221 163 YNYYTSKRWGEVDSYDLCLNSS 184
Cdd:pfam13189 154 YKYYTGKDWGDAENYDLVINTS 175
PRK04182 PRK04182
cytidylate kinase; Provisional
4-202 9.54e-09

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 52.89  E-value: 9.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221   4 IITIGRQYGSAGHSIGKILADDLGIKYYDK-ELLERAAKDSGLC----QELFENHDEkptnsflyslvmdsysfgygstm 78
Cdd:PRK04182    2 IITISGPPGSGKTTVARLLAEKLGLKHVSAgEIFRELAKERGMSleefNKYAEEDPE----------------------- 58
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221  79 MDMPLNQKvflaQFDAIKKisqDGPCVIVGRCADYALEENPNvLSIFIKADMQDRIRRIAKLYDLSDAKAKDKIT---KI 155
Cdd:PRK04182   59 IDKEIDRR----QLEIAEK---EDNVVLEGRLAGWMAKDYAD-LKIWLKAPLEVRAERIAEREGISVEEALEETIereES 130
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1468633221 156 DKQRasYYNYYtskrwgEVD-----SYDLCLNSSVFGIDGTVDMIKQAIEVK 202
Cdd:PRK04182  131 EAKR--YKEYY------GIDiddlsIYDLVINTSRWDPEGVFDIILTAIDKL 174
 
Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
4-204 1.06e-75

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 225.86  E-value: 1.06e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221   4 IITIGRQYGSAGHSIGKILADDLGIKYYDKELLERAAKDSGLCQELFENHDEKPTNSFLyslvmdsysfgygstmMDMPL 83
Cdd:COG1102     2 VITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKAPSLLY----------------RDTAE 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221  84 NQKVFLAQFDAIKKISQDGPCVIVGRCADYALEENPNVLSIFIKADMQDRIRRIAKLYDLSDAKAKDKITKIDKQRASYY 163
Cdd:COG1102    66 EDEIDRALDKVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYY 145
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1468633221 164 NYYTSKRWGEVDSYDLCLNSSVFGIDGTVDMIKQAIEVKEA 204
Cdd:COG1102   146 KYYYGIDWGDPSNYDLVINTSRLGIEEAVDLILAAIEAREK 186
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
4-184 1.70e-70

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 212.49  E-value: 1.70e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221   4 IITIGRQYGSAGHSIGKILADDLGIKYYDKELLERAAKDSGLCQELFENHDEKPT-NSFLYSLVMdsysfgyGSTMMDMP 82
Cdd:pfam13189   1 VITISRQYGSGGTTIAKKLAEKLGYPFYDREILDEIAKELGISEEEFELFDEKSRlSSFLYSLAG-------GRVRGDAL 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221  83 LNQKVFLAQFDAIKKISQDGPCVIVGRCADYALEENPNVLSIFIKADMQDRIRRIAKLYDLSDAKAKDKITKIDKQRASY 162
Cdd:pfam13189  74 SDDRLFDAQSKVIRELAAEDNCVIVGRGADYILKDIPNVLRVFLTAPLEDRVKRVMEREGLSEEEARELIKETDKRRAKY 153
                         170       180
                  ....*....|....*....|..
gi 1468633221 163 YNYYTSKRWGEVDSYDLCLNSS 184
Cdd:pfam13189 154 YKYYTGKDWGDAENYDLVINTS 175
PRK04182 PRK04182
cytidylate kinase; Provisional
4-202 9.54e-09

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 52.89  E-value: 9.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221   4 IITIGRQYGSAGHSIGKILADDLGIKYYDK-ELLERAAKDSGLC----QELFENHDEkptnsflyslvmdsysfgygstm 78
Cdd:PRK04182    2 IITISGPPGSGKTTVARLLAEKLGLKHVSAgEIFRELAKERGMSleefNKYAEEDPE----------------------- 58
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468633221  79 MDMPLNQKvflaQFDAIKKisqDGPCVIVGRCADYALEENPNvLSIFIKADMQDRIRRIAKLYDLSDAKAKDKIT---KI 155
Cdd:PRK04182   59 IDKEIDRR----QLEIAEK---EDNVVLEGRLAGWMAKDYAD-LKIWLKAPLEVRAERIAEREGISVEEALEETIereES 130
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1468633221 156 DKQRasYYNYYtskrwgEVD-----SYDLCLNSSVFGIDGTVDMIKQAIEVK 202
Cdd:PRK04182  131 EAKR--YKEYY------GIDiddlsIYDLVINTSRWDPEGVFDIILTAIDKL 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH