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Conserved domains on  [gi|1468274477|ref|WP_117239853|]
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MULTISPECIES: entry exclusion protein 1 [Enterobacteriaceae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
rep_pAB02_ORF2 super family cl45742
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 4-116 2.08e-09

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


The actual alignment was detected with superfamily member NF038291:

Pssm-ID: 468456  Cd Length: 172  Bit Score: 52.33  E-value: 2.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468274477   4 VTVRQATELTGKARSSLYRDMAKGRVSyrTEADGgrVVDTSELIRVYGElRQGETHERDGLRLPDETEKTASDALIAEIK 83
Cdd:NF038291    3 LSVSEASKLFNISRSTIYKAIKKGDLS--KDSDG--LIDLSEAIRVFGE-PSKKSTDVNTSQSINSQKSTEVELLKQQVD 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1468274477  84 ALREEV-------AGLRQEMQAM-RLLEHKPETAETPAGTP 116
Cdd:NF038291   78 MLKKQLeqakereSFYQKQIDDLqLLLEYKAPKPNMTTFTD 118
 
Name Accession Description Interval E-value
rep_pAB02_ORF2 NF038291
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 4-116 2.08e-09

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


Pssm-ID: 468456  Cd Length: 172  Bit Score: 52.33  E-value: 2.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468274477   4 VTVRQATELTGKARSSLYRDMAKGRVSyrTEADGgrVVDTSELIRVYGElRQGETHERDGLRLPDETEKTASDALIAEIK 83
Cdd:NF038291    3 LSVSEASKLFNISRSTIYKAIKKGDLS--KDSDG--LIDLSEAIRVFGE-PSKKSTDVNTSQSINSQKSTEVELLKQQVD 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1468274477  84 ALREEV-------AGLRQEMQAM-RLLEHKPETAETPAGTP 116
Cdd:NF038291   78 MLKKQLeqakereSFYQKQIDDLqLLLEYKAPKPNMTTFTD 118
PanE COG1893
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ...
 5-85 2.71e-03

Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 441497 [Multi-domain]  Cd Length: 305  Bit Score: 35.99  E-value: 2.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468274477   5 TVRQATELTGKARSSLYRDMAKGRvsyRTEADG--GRVVdtselirvygelRQGETHerdGLRLPdetektASDALIAEI 82
Cdd:COG1893   242 RVAAVAEATADNRSSMLQDLEAGR---PTEIDAinGAVV------------RLARRL---GVPTP------VNEALYALL 297


                  ...
gi 1468274477  83 KAL 85
Cdd:COG1893   298 KAL 300
 
Name Accession Description Interval E-value
rep_pAB02_ORF2 NF038291
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 4-116 2.08e-09

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


Pssm-ID: 468456  Cd Length: 172  Bit Score: 52.33  E-value: 2.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468274477   4 VTVRQATELTGKARSSLYRDMAKGRVSyrTEADGgrVVDTSELIRVYGElRQGETHERDGLRLPDETEKTASDALIAEIK 83
Cdd:NF038291    3 LSVSEASKLFNISRSTIYKAIKKGDLS--KDSDG--LIDLSEAIRVFGE-PSKKSTDVNTSQSINSQKSTEVELLKQQVD 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1468274477  84 ALREEV-------AGLRQEMQAM-RLLEHKPETAETPAGTP 116
Cdd:NF038291   78 MLKKQLeqakereSFYQKQIDDLqLLLEYKAPKPNMTTFTD 118
PanE COG1893
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ...
 5-85 2.71e-03

Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 441497 [Multi-domain]  Cd Length: 305  Bit Score: 35.99  E-value: 2.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468274477   5 TVRQATELTGKARSSLYRDMAKGRvsyRTEADG--GRVVdtselirvygelRQGETHerdGLRLPdetektASDALIAEI 82
Cdd:COG1893   242 RVAAVAEATADNRSSMLQDLEAGR---PTEIDAinGAVV------------RLARRL---GVPTP------VNEALYALL 297


                  ...
gi 1468274477  83 KAL 85
Cdd:COG1893   298 KAL 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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