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Conserved domains on  [gi|1440955433|ref|WP_114710568|]
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IS21-like element ISRel16 family helper ATPase IstB [Rhizobium grahamii]

Protein Classification

ATP-binding protein( domain architecture ID 11445237)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain, similar to the ATPase region of Aquifex aeolicus DnaC helicase loader and to Mycobacterium tuberculosis putative ATP-binding protein Rv3427c in insertion sequence

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-242 1.36e-108

DNA replication protein DnaC [Replication, recombination and repair];


:

Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 312.87  E-value: 1.36e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433   1 MLAHPTLDKLNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDR 80
Cdd:COG1484     1 MLMEELKELLKALKLPGMAEALDELLAQAACDELSYEEFLALLLEAEVAEREQRRIERRLKAARFPAAKTLEDFDFDAQP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  81 GLDRALFMKLIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGH 160
Cdd:COG1484    81 GLDRRQILELATLDFIERGENLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 161 VQLLILDDWGLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRN 240
Cdd:COG1484   161 VDLLILDELGYLPLDAEGAELLFELISDRYERRSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLK 240


                  ..
gi 1440955433 241 QR 242
Cdd:COG1484   241 EA 242
 
Name Accession Description Interval E-value
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-242 1.36e-108

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 312.87  E-value: 1.36e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433   1 MLAHPTLDKLNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDR 80
Cdd:COG1484     1 MLMEELKELLKALKLPGMAEALDELLAQAACDELSYEEFLALLLEAEVAEREQRRIERRLKAARFPAAKTLEDFDFDAQP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  81 GLDRALFMKLIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGH 160
Cdd:COG1484    81 GLDRRQILELATLDFIERGENLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 161 VQLLILDDWGLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRN 240
Cdd:COG1484   161 VDLLILDELGYLPLDAEGAELLFELISDRYERRSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLK 240


                  ..
gi 1440955433 241 QR 242
Cdd:COG1484   241 EA 242
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 10-241 5.66e-101

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 293.22  E-value: 5.66e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  10 LNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDRGLDRALFMK 89
Cdd:NF038214    1 LRQLKLPGMARALEELAEQAAREELSFEEFLALLLEAELAERENRRIERRLKRARFPAAKTLEDFDFTAAPGLDKAQIRE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  90 LIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDDW 169
Cdd:NF038214   81 LATLDFIERAENVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDEL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1440955433 170 GLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRNQ 241
Cdd:NF038214  161 GYLPFSREGANLLFELIADRYERGSTIITSNLPFSEWGEVFGDPTLAAAILDRLVHHAHILELKGESYRLKE 232
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 10-245 4.10e-76

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 230.41  E-value: 4.10e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  10 LNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDRGLDRALFMK 89
Cdd:pfam01695   3 LKQLKLPGMAEAWEELSQQAASTSLSYEEFLEHLLEEELAWRDTRRLERLLRMAKLPPHKTLEDFDFTFAPGLDQRIVAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  90 LIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDDW 169
Cdd:pfam01695  83 LASLSFIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEW 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1440955433 170 GLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRNQRRKS 245
Cdd:pfam01695 163 GYLPLDQAEANLLFQVISKRYEHRSIILTSNLPFGEWGQVFGDAVLATAILDRLLHHCHIVPIKGESYRLKTKSEA 238
PRK06526 PRK06526
transposase; Provisional
 18-242 5.58e-38

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 133.07  E-value: 5.58e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  18 MAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDRGLDRALFMKLIGGDWID 97
Cdd:PRK06526   17 LAGAVERLAERARAESWSHEEFLAACLQREVAARESHGGEGRIRAARFPARKSLEEFDFDHQRSLKRDTIAHLGTLDFVT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  98 AHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDDWGLEPLNEQ 177
Cdd:PRK06526   97 GKENVVFLGPPGTGKTHLAIGLGIRACQAGHRVLFATAAQWVARLAAAHHAGRLQAELVKLGRYPLLIVDEVGYIPFEPE 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1440955433 178 ARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRNQR 242
Cdd:PRK06526  177 AANLFFQLVSSRYERASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHHAEVISLKGDSYRLKDR 241
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 81-202 3.47e-10

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 56.77  E-value: 3.47e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  81 GLDRALfMKLIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRT--- 157
Cdd:cd00009     2 GQEEAI-EALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFela 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1440955433 158 -LGHVQLLILDDWGLEPLNEQARhdLLEILED------RYGRRSTIITSQLP 202
Cdd:cd00009    81 eKAKPGVLFIDEIDSLSRGAQNA--LLRVLETlndlriDRENVRVIGATNRP 130
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 99-202 4.69e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.28  E-value: 4.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433   99 HDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQ---------------L 163
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELrlrlalalarklkpdV 81

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1440955433  164 LILD------DWGLEPLNEQARHDLLEILEDRYGRRSTIITSQLP 202
Cdd:smart00382  82 LILDeitsllDAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDE 126
 
Name Accession Description Interval E-value
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-242 1.36e-108

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 312.87  E-value: 1.36e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433   1 MLAHPTLDKLNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDR 80
Cdd:COG1484     1 MLMEELKELLKALKLPGMAEALDELLAQAACDELSYEEFLALLLEAEVAEREQRRIERRLKAARFPAAKTLEDFDFDAQP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  81 GLDRALFMKLIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGH 160
Cdd:COG1484    81 GLDRRQILELATLDFIERGENLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 161 VQLLILDDWGLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRN 240
Cdd:COG1484   161 VDLLILDELGYLPLDAEGAELLFELISDRYERRSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLK 240


                  ..
gi 1440955433 241 QR 242
Cdd:COG1484   241 EA 242
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 10-241 5.66e-101

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 293.22  E-value: 5.66e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  10 LNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDRGLDRALFMK 89
Cdd:NF038214    1 LRQLKLPGMARALEELAEQAAREELSFEEFLALLLEAELAERENRRIERRLKRARFPAAKTLEDFDFTAAPGLDKAQIRE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  90 LIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDDW 169
Cdd:NF038214   81 LATLDFIERAENVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDEL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1440955433 170 GLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRNQ 241
Cdd:NF038214  161 GYLPFSREGANLLFELIADRYERGSTIITSNLPFSEWGEVFGDPTLAAAILDRLVHHAHILELKGESYRLKE 232
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 10-245 4.10e-76

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 230.41  E-value: 4.10e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  10 LNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDRGLDRALFMK 89
Cdd:pfam01695   3 LKQLKLPGMAEAWEELSQQAASTSLSYEEFLEHLLEEELAWRDTRRLERLLRMAKLPPHKTLEDFDFTFAPGLDQRIVAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  90 LIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDDW 169
Cdd:pfam01695  83 LASLSFIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEW 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1440955433 170 GLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRNQRRKS 245
Cdd:pfam01695 163 GYLPLDQAEANLLFQVISKRYEHRSIILTSNLPFGEWGQVFGDAVLATAILDRLLHHCHIVPIKGESYRLKTKSEA 238
PRK06526 PRK06526
transposase; Provisional
 18-242 5.58e-38

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 133.07  E-value: 5.58e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  18 MAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDRGLDRALFMKLIGGDWID 97
Cdd:PRK06526   17 LAGAVERLAERARAESWSHEEFLAACLQREVAARESHGGEGRIRAARFPARKSLEEFDFDHQRSLKRDTIAHLGTLDFVT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  98 AHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDDWGLEPLNEQ 177
Cdd:PRK06526   97 GKENVVFLGPPGTGKTHLAIGLGIRACQAGHRVLFATAAQWVARLAAAHHAGRLQAELVKLGRYPLLIVDEVGYIPFEPE 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1440955433 178 ARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRRNQR 242
Cdd:PRK06526  177 AANLFFQLVSSRYERASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHHAEVISLKGDSYRLKDR 241
PRK09183 PRK09183
transposase/IS protein; Provisional
 2-245 3.12e-35

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 125.97  E-value: 3.12e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433   2 LAHPTLDKL-NAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDR 80
Cdd:PRK09183    4 LQHQRLMALcGQLQLESLISAAPALAQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFAT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  81 GLDRALFMKLIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYAR-LQRTLG 159
Cdd:PRK09183   84 GAPQKQLQSLRSLSFIERNENIVLLGPSGVGKTHLAIALGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTtLQRGVM 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 160 HVQLLILDDWGLEPLN-EQARHdLLEILEDRYGRRSTIITSQLPVSAWHEII-GNPTYADAILDRLVHNAHRIDLSGESL 237
Cdd:PRK09183  164 APRLLIIDEIGYLPFSqEEANL-FFQVIAKRYEKGSMILTSNLPFGQWDQTFaGDAALTSAMLDRLLHHSHVVQIKGESY 242


                  ....*...
gi 1440955433 238 RRNQRRKS 245
Cdd:PRK09183  243 RLKQKRKA 250
PRK08181 PRK08181
transposase; Validated
 10-239 9.13e-24

transposase; Validated


Pssm-ID: 136670 [Multi-domain]  Cd Length: 269  Bit Score: 96.15  E-value: 9.13e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  10 LNAMGLTGMAKAFNELISNGESEQLSHAEWLGLLLEREWSSRHDRKLAARLRFAKLRHHAVPEDVDYRSDRGLDRALFMK 89
Cdd:PRK08181   16 LNELRLPTIKTLWPQFAEQADKEGWPAARFLAAIAEHELAERARRRIERHLAEAHLPPGKTLDSFDFEAVPMVSKAQVMA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  90 LIGGD-WIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDD 168
Cdd:PRK08181   96 IAAGDsWLAKGANLLLFGPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLQVARRELQLESAIAKLDKFDLLILDD 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1440955433 169 WGLEPLNEQARHDLLEILEDRYGRRSTIITSQLPVSAWHEIIGNPTYADAILDRLVHNAHRIDLSGESLRR 239
Cdd:PRK08181  176 LAYVTKDQAETSVLFELISARYERRSILITANQPFGEWNRVFPDPAMTLAAVDRLVHHATIFEMNVESYRR 246
PRK08116 PRK08116
hypothetical protein; Validated
 102-239 2.31e-11

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 61.96  E-value: 2.31e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 102 LAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGD-GRYARLQ--RTLGHVQLLILDDWGLEPLNEQA 178
Cdd:PRK08116  117 LLLWGSVGTGKTYLAACIANELIEKGVPVIFVNFPQLLNRIKSTYKSsGKEDENEiiRSLVNADLLILDDLGAERDTEWA 196

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1440955433 179 RHDLLEILEDRY-GRRSTIITSQLPVSAWHEIIGNPTYadailDRLVHNAHRIDLSGESLRR 239
Cdd:PRK08116  197 REKVYNIIDSRYrKGLPTIVTTNLSLEELKNQYGKRIY-----DRILEMCTPVENEGKSYRK 253
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 81-202 3.47e-10

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 56.77  E-value: 3.47e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  81 GLDRALfMKLIGGDWIDAHDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRT--- 157
Cdd:cd00009     2 GQEEAI-EALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFela 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1440955433 158 -LGHVQLLILDDWGLEPLNEQARhdLLEILED------RYGRRSTIITSQLP 202
Cdd:cd00009    81 eKAKPGVLFIDEIDSLSRGAQNA--LLRVLETlndlriDRENVRVIGATNRP 130
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 99-242 5.36e-10

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 58.37  E-value: 5.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  99 HDNLAICGPSGVGKSWLACALGhKACRDD-RSVLYQRVPRLFANLalahgdgRYARLQR---------TLGHVQLLILDD 168
Cdd:PRK06835  183 NENLLFYGNTGTGKTFLSNCIA-KELLDRgKSVIYRTADELIEIL-------REIRFNNdkeleevydLLINCDLLIIDD 254

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1440955433 169 WGLEPLNEQARHDLLEILEDRYGRR-STIITSQLPVSawhEIIGnpTYADAILDRLVHNAHRIDLSGESLRRNQR 242
Cdd:PRK06835  255 LGTEKITEFSKSELFNLINKRLLRQkKMIISTNLSLE---ELLK--TYSERISSRLLGNFTLLKFYGEDIRIKKN 324
PRK12377 PRK12377
putative replication protein; Provisional
 37-243 9.89e-08

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 51.37  E-value: 9.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  37 AEWlgllleREWSSRHDRKLAARLRfaKLRHHAVPEDVDYRS-----------------DRGLDRALFM-KLIGGDWIDA 98
Cdd:PRK12377   29 DEW------REWQLAEGRKRSEEIN--RQNQQLRVEKILNRSgiqplhrkcsfanyqvqNDGQRYALSQaKSIADELMTG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433  99 HDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRY-ARLQRTLGHVQLLILDDWGL--EPLN 175
Cdd:PRK12377  101 CTNFVFSGKPGTGKNHLAAAIGNRLLAKGRSVIVVTVPDVMSRLHESYDNGQSgEKFLQELCKVDLLVLDEIGIqrETKN 180

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 176 EQARhdLLEILEDRYGR-RSTIITSQLPVSAWHEIIGnptyaDAILDRLVHNAHR-IDLSGESLRRNQRR 243
Cdd:PRK12377  181 EQVV--LNQIIDRRTASmRSVGMLTNLNHEAMSTLLG-----ERVMDRMTMNGGRwVNFNWESWRPNVSH 243
PRK08939 PRK08939
primosomal protein DnaI; Reviewed
 106-189 1.34e-04

primosomal protein DnaI; Reviewed


Pssm-ID: 236353 [Multi-domain]  Cd Length: 306  Bit Score: 42.16  E-value: 1.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 106 GPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQLLILDDWGLEPLNEQARHDLLE- 184
Cdd:PRK08939  163 GDFGVGKSYLLAAIANELAKKGVSSTLLHFPEFIRELKNSISDGSVKEKIDAVKEAPVLMLDDIGAEQMSSWVRDEVLGv 242


                  ....*
gi 1440955433 185 ILEDR 189
Cdd:PRK08939  243 ILQYR 247
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 99-202 4.69e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.28  E-value: 4.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433   99 HDNLAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGDGRYARLQRTLGHVQ---------------L 163
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELrlrlalalarklkpdV 81

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1440955433  164 LILD------DWGLEPLNEQARHDLLEILEDRYGRRSTIITSQLP 202
Cdd:smart00382  82 LILDeitsllDAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDE 126
AAA_22 pfam13401
AAA domain;
102-197 2.41e-03

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 36.94  E-value: 2.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440955433 102 LAICGPSGVGKSWLACALGHKACRDDRSVLYQRVPRLFANLALAHGdgryarlqrtlghvqllILDDWGLEPLNEQARHD 181
Cdd:pfam13401   8 LVLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSPKDLLRA-----------------LLRALGLPLSGRLSKEE 70

                          90
                  ....*....|....*....
gi 1440955433 182 LLEILED---RYGRRSTII 197
Cdd:pfam13401  71 LLAALQQlllALAVAVVLI 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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