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Conserved domains on  [gi|1427749678|ref|WP_113613326|]
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autotransporter outer membrane beta-barrel domain-containing protein [Lawsonia intracellularis]

Protein Classification

autotransporter outer membrane beta-barrel domain-containing protein( domain architecture ID 10510333)

autotransporter outer membrane beta-barrel domain-containing protein similar to Neisseria meningitidis autotransporter NalP, a virulence-related protein which is secreted via the C-terminal translocator domain

CATH:  2.40.128.130
Gene Ontology:  GO:0016020
PubMed:  9778731|23567321
SCOP:  4001769

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
AidA super family cl34620
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
118-549 1.49e-09

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


The actual alignment was detected with superfamily member COG3468:

Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 61.89  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 118 IIGAGISNRGLVTVTGSVNMKLENVSVTRGIYGGVYTQNGHVLGSINMHLKNVQTPLLIGSGVSNGPNRITVNGDINIDV 197
Cdd:COG3468     5 GGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGT 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 198 EDSRIQYVNITGEVDAGIKGNATLTVKKSTvelINSGRGNILGNLKISIADSNIRGLSPVDFGSSVYGDTSINVINSQIN 277
Cdd:COG3468    85 GGNSTGGGGGNSGTGGTGGGGGGGGSGNGG---GGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGT 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 278 DITLIPRAGGMLVGPVTLDITSSTIQNIQCGPVSQNNQLNTLNVTVNTSNITNLNLGSVEGHTISTTATVTDSNITNLNV 357
Cdd:COG3468   162 GSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGG 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 358 GTFNGLGVTENASVIINSGNITNLNVGTNVIAAATTINSSATIHDGLIANLTLGSQGNGRTMIATANVNGGTIGLLTMGS 437
Cdd:COG3468   242 GGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGSN 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 438 ENFIPGTRPITELAILNMSGGLIERIIVGNANSSTINFTPGKRS---IVKTINGPELPYLVNIQKGAMTQWGTKNMPFLL 514
Cdd:COG3468   322 AGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSgggGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTG 401
                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1427749678 515 DTRNLILSGTLITSNIQLAD-LSITNLFVANGGTLV 549
Cdd:COG3468   402 NNGGGGVGGGGGGGLTLTGGtLTVNGNYTGNNGTLV 437
Autotransporter super family cl47844
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
677-870 2.66e-06

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


The actual alignment was detected with superfamily member pfam03797:

Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 49.69  E-value: 2.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 677 LWINVQGGHESLDTSIG-SKAKMPWIMATAGYDYlqqlpRLDMKALYGLAFGASKGKSKWSSVNStKNDAELGMVSGYvG 755
Cdd:pfam03797   1 VWARGFGGRGKQDGDGGaAGYDADTGGLQVGADY-----RLGDNLRLGVAFGYSRSDADVDGRGG-SGDSDSYSLGLY-G 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 756 LIHNKTGLYSTLTLQLASSKLHTNSTGFYRNFKWTETTPTEA------LELGWKYTFNNGIKMNPRGQLIFEQTSKHHFD 829
Cdd:pfam03797  74 TYYGDGGWYLDGGLGYGWHDNDTRRSVDLGGFSETAKGDYDGngfgasLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFT 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1427749678 830 L--GIQNDKAILDKSQLITSSLGITVEYKLPVT-TPINLYAGIE 870
Cdd:pfam03797 154 EsgGAAALSVDSQSYDSLTGRLGLRLSYTFDLGgGTLTPYARLG 197
 
Name Accession Description Interval E-value
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
118-549 1.49e-09

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 61.89  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 118 IIGAGISNRGLVTVTGSVNMKLENVSVTRGIYGGVYTQNGHVLGSINMHLKNVQTPLLIGSGVSNGPNRITVNGDINIDV 197
Cdd:COG3468     5 GGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGT 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 198 EDSRIQYVNITGEVDAGIKGNATLTVKKSTvelINSGRGNILGNLKISIADSNIRGLSPVDFGSSVYGDTSINVINSQIN 277
Cdd:COG3468    85 GGNSTGGGGGNSGTGGTGGGGGGGGSGNGG---GGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGT 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 278 DITLIPRAGGMLVGPVTLDITSSTIQNIQCGPVSQNNQLNTLNVTVNTSNITNLNLGSVEGHTISTTATVTDSNITNLNV 357
Cdd:COG3468   162 GSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGG 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 358 GTFNGLGVTENASVIINSGNITNLNVGTNVIAAATTINSSATIHDGLIANLTLGSQGNGRTMIATANVNGGTIGLLTMGS 437
Cdd:COG3468   242 GGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGSN 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 438 ENFIPGTRPITELAILNMSGGLIERIIVGNANSSTINFTPGKRS---IVKTINGPELPYLVNIQKGAMTQWGTKNMPFLL 514
Cdd:COG3468   322 AGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSgggGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTG 401
                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1427749678 515 DTRNLILSGTLITSNIQLAD-LSITNLFVANGGTLV 549
Cdd:COG3468   402 NNGGGGVGGGGGGGLTLTGGtLTVNGNYTGNNGTLV 437
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
677-870 2.66e-06

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 49.69  E-value: 2.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 677 LWINVQGGHESLDTSIG-SKAKMPWIMATAGYDYlqqlpRLDMKALYGLAFGASKGKSKWSSVNStKNDAELGMVSGYvG 755
Cdd:pfam03797   1 VWARGFGGRGKQDGDGGaAGYDADTGGLQVGADY-----RLGDNLRLGVAFGYSRSDADVDGRGG-SGDSDSYSLGLY-G 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 756 LIHNKTGLYSTLTLQLASSKLHTNSTGFYRNFKWTETTPTEA------LELGWKYTFNNGIKMNPRGQLIFEQTSKHHFD 829
Cdd:pfam03797  74 TYYGDGGWYLDGGLGYGWHDNDTRRSVDLGGFSETAKGDYDGngfgasLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFT 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1427749678 830 L--GIQNDKAILDKSQLITSSLGITVEYKLPVT-TPINLYAGIE 870
Cdd:pfam03797 154 EsgGAAALSVDSQSYDSLTGRLGLRLSYTFDLGgGTLTPYARLG 197
 
Name Accession Description Interval E-value
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
118-549 1.49e-09

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 61.89  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 118 IIGAGISNRGLVTVTGSVNMKLENVSVTRGIYGGVYTQNGHVLGSINMHLKNVQTPLLIGSGVSNGPNRITVNGDINIDV 197
Cdd:COG3468     5 GGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGT 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 198 EDSRIQYVNITGEVDAGIKGNATLTVKKSTvelINSGRGNILGNLKISIADSNIRGLSPVDFGSSVYGDTSINVINSQIN 277
Cdd:COG3468    85 GGNSTGGGGGNSGTGGTGGGGGGGGSGNGG---GGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGT 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 278 DITLIPRAGGMLVGPVTLDITSSTIQNIQCGPVSQNNQLNTLNVTVNTSNITNLNLGSVEGHTISTTATVTDSNITNLNV 357
Cdd:COG3468   162 GSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGG 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 358 GTFNGLGVTENASVIINSGNITNLNVGTNVIAAATTINSSATIHDGLIANLTLGSQGNGRTMIATANVNGGTIGLLTMGS 437
Cdd:COG3468   242 GGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGSN 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 438 ENFIPGTRPITELAILNMSGGLIERIIVGNANSSTINFTPGKRS---IVKTINGPELPYLVNIQKGAMTQWGTKNMPFLL 514
Cdd:COG3468   322 AGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSgggGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTG 401
                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1427749678 515 DTRNLILSGTLITSNIQLAD-LSITNLFVANGGTLV 549
Cdd:COG3468   402 NNGGGGVGGGGGGGLTLTGGtLTVNGNYTGNNGTLV 437
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
677-870 2.66e-06

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 49.69  E-value: 2.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 677 LWINVQGGHESLDTSIG-SKAKMPWIMATAGYDYlqqlpRLDMKALYGLAFGASKGKSKWSSVNStKNDAELGMVSGYvG 755
Cdd:pfam03797   1 VWARGFGGRGKQDGDGGaAGYDADTGGLQVGADY-----RLGDNLRLGVAFGYSRSDADVDGRGG-SGDSDSYSLGLY-G 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 756 LIHNKTGLYSTLTLQLASSKLHTNSTGFYRNFKWTETTPTEA------LELGWKYTFNNGIKMNPRGQLIFEQTSKHHFD 829
Cdd:pfam03797  74 TYYGDGGWYLDGGLGYGWHDNDTRRSVDLGGFSETAKGDYDGngfgasLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFT 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1427749678 830 L--GIQNDKAILDKSQLITSSLGITVEYKLPVT-TPINLYAGIE 870
Cdd:pfam03797 154 EsgGAAALSVDSQSYDSLTGRLGLRLSYTFDLGgGTLTPYARLG 197
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
32-430 6.33e-06

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 50.16  E-value: 6.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678  32 YAADVFFGGRTETLINVNKPFDSFFGGSDSTIGTLETGPTNLTFTTVGAFRNSVFRIIGGGRSSFNNPNTVKGNVTLTVY 111
Cdd:COG4625   128 GAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGG 207
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 112 NTDVERIIGAGISNRGLVTVTGSVNMKLENVSVTRGIYGGVYTQNGHVLGSINMHLKNVQTPLLIGSGVSNGPNRITVNG 191
Cdd:COG4625   208 GGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGS 287
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 192 DINIDVEDSRIQYVNITGEVDAGIKGNATLTVKKSTVELINSGRGNILGNLKISIADSNIRGLSPVDFGSSVYGDTSINV 271
Cdd:COG4625   288 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGG 367
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 272 INSQINDITLIPRAGGMLVGPVTLDITSSTIQNIQCGPVSQNNQLNTLNVTVNTSNITNLNLGSVEGHTISTTATVTDSN 351
Cdd:COG4625   368 GGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATG 447
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 352 ITNLNVGTFNGLGVTENASVIINSGNITNLNVGTNVIAAATTINS--SATIHDGLIANLTLGSQGNGRTMIA-TANVNGG 428
Cdd:COG4625   448 GGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGggNYTQSAGSTLAVEVDAANSDRLVVTgTATLNGG 527

                  ..
gi 1427749678 429 TI 430
Cdd:COG4625   528 TV 529
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
38-406 6.76e-06

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 49.94  E-value: 6.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678  38 FGGRTETLINVNKPFDSFFGGSDSTIGTLETGPTNLTFTTVGAFRNSVFRIIGGGRSSFNNPNTVKGNVTLTVYNTDVER 117
Cdd:COG3468    56 GGGGGGGAGGGGGGAGSGGGLAGAGSGGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGS 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 118 IIGAGISNRGLVTVTGSVNMKLE-----NVSVTRGIYGGVYTQNGHVLGSINMHLKNVQTPLLIGSGVSNGPNRITVNGD 192
Cdd:COG3468   136 AGGGGGGGGGGTGVGGTGAAAAGggtgsGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGG 215
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 193 INIDVEDSRIQYVNITGEVDAGIKGNATLTVKKSTVELINSGRGNILGNLKISIADSNIRGLSPVDFGSSVYGDTSINVI 272
Cdd:COG3468   216 GGGGGAGGATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTG 295
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678 273 NSQINDITLIPRAGGMLVGPVTLDITSSTIQNIQCGPVSQNNQLNTLNVTVNTSNITNLNLGSVEGHTISTTATVTDSNI 352
Cdd:COG3468   296 GGGTASTGGGGGGGGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGG 375
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1427749678 353 TNLNVGTFNGLGVTENASVIINSGNITNLNVGTNVIAAAT--------TINSSATIHDGLIA 406
Cdd:COG3468   376 GGGAGGGGANTGSDGVGTGLTTGGTGNNGGGGVGGGGGGGltltggtlTVNGNYTGNNGTLV 437
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
33-507 3.64e-04

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 44.76  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678   33 AADVFFGGRTETLINVNKPFDSFFGGSDSTIGTLETGPTNLTFTTVGAFRNSVFRIIGGGRSSFNNPNTVKGNVTLTVYN 112
Cdd:COG3210    235 GTGAGVISTGGTDISSLSVAAGAGTGGAGGTGNAGNTTIGTTVTGTNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLGG 314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678  113 TDVERIIGAGISNRGLVTVTGSVNMKLENVSVTRGIYGGVYTQNGHVLGSINmhLKNVQTPLLIGSGVSNGPNRITVNGD 192
Cdd:COG3210    315 GTAAGITTTNTVGGNGDGNNTTANSGAGLVSGGTGGNNGTTGTGAGSGLTGT--GNGGGLTTAGAGTVASTVGTATASTG 392
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678  193 INIDVEDSRIQYVNITGEVDAGIKGNATLTVKKSTVELINSGRGNILGNLKISIADSNIRGLSPVDFGSSVYGDTSINVI 272
Cdd:COG3210    393 NASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTV 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678  273 NSQINDITLIPRAGGMLVGPVTLDITSSTIQNIQCGPVSQNNQLNTLNVTVNTSNITNLNLGSVEGHTISTTATVTDSNI 352
Cdd:COG3210    473 TNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGA 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678  353 TNLNVGTFNGLGVTENASVIINSGNITNLNVGTNVIAAATTINSSATIHDGLIANLTLGSQGNGRTMIAT-----ANVNG 427
Cdd:COG3210    553 SGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGaganaTGGGA 632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1427749678  428 GTIGLLTMGSENFIPGTRPITELAILNMSGGLIERIIVGNANSSTINFTPGKRSIVKTINGPELPYLVNIQKGAMTQWGT 507
Cdd:COG3210    633 GLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGS 712
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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