|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
65-725 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 563.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 65 YFLALVKDEPVKNNTalkkSLYEMTQSTTVYFGTGETLGTLnADVQREVIKYNKMSPHVIDALIATEDENFYKHNGIVPK 144
Cdd:COG0744 33 LVALYVADLPDPEEL----EDLALPQTSTIYDRDGTLIATL-GDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 145 AFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEMMLSFKVEKSLSKKEIIEAYLNVVSFGRNtngqnIA 224
Cdd:COG0744 108 GIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG-----AY 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 225 GVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgefkkdKDLKFGFERQQYVLMRMYQEKKITKAQYEQAKK 304
Cdd:COG0744 183 GIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPY---------RNPEAAKERRNLVLDRMVEQGYITQAEADAAKA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 305 FNLKKSFTKDfEVPNEKYPFLTQEVESRAIDIlkyiFAEKDnisrqeldetpvlqekyvgianraIRNNGYIIDTTIHKK 384
Cdd:COG0744 254 EPLTLVPPPN-GAAAGKYPYFVDYVRRELEEL----LGEDD------------------------LYRGGLKIYTTLDPK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 385 IFDTMDQIkdnpnyysyARNANVNGKTKaiNMEVGVLLKENDSGKILSFIGGRNHNDSQNNHATKTKRSPGSTIKPLlTY 464
Cdd:COG0744 305 LQKAAEKA---------VKNVLPEGKPG--GLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPF-VY 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 465 APAIEYGITaPEAALLDKQFNYNG--YSPENYARMEYNVVTTRYALENSLNLSTLRLYSGIQDRKPWELLQKMNfnIPKS 542
Cdd:COG0744 373 AAALEQGYT-PATTVDDEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLG--ITSP 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 543 EQENLSLALGATDITLENNVDGFSTLANKGNYQESYMIESIKTRDGKVIYQHNARPVRIYSPETAYITTDMLRGVLDTGS 622
Cdd:COG0744 450 LDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGT 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 623 GYQLKgtfMYNQDWAGKTGTAQEGKDSLFIGYNPKVTMGIWMGYD--VPTSFDEENHYQLRLWRDIINQIttqdqLQMGV 700
Cdd:COG0744 530 GRAAR---LPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDdnSPMGYVTGGSLPAPIWRDFMEAA-----LEGLP 601
|
650 660
....*....|....*....|....*
gi 1409089500 701 GERFNQPDDVKKIemCQYSMSQKGS 725
Cdd:COG0744 602 VEDFPKPSGVVRI--DEPSPTPSGT 624
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
110-691 |
7.50e-147 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 441.31 E-value: 7.50e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 110 QREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEM 189
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 190 MLSFKVEKSLSKKEIIEAYLNVVSFGRNTNGqniagVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgefk 269
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYG-----IEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPF------- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 270 kdKDLKFGFERQQYVLMRMYQEKKITKAQYEQAKK--FNLKKSFTKDFEVpneKYPFLTQEVesraidilkyifaekdni 347
Cdd:TIGR02074 149 --KNPERAKDRRNLVLSNMVENGYITAEEAEEAINepIQLYLQTKKSEQY---KAPYFVDYV------------------ 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 348 sRQELDEtpvlqekyvgIANRAIRNNGYIIDTTIhkkifdtmdqikdNPNYYSYARNANVNGKTKAINM-----EVGVLL 422
Cdd:TIGR02074 206 -IQELEE----------EYGEELYTGGLKIYTTL-------------DLDAQKAAEKVLNTGLRVAGRRdgddlQAALVA 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 423 KENDSGKILSFIGGRNHNDSQNNHATKTKRSPGSTIKPLLtYAPAIEYGITaPEAALLDKQFNYNG---YSPENYARMEY 499
Cdd:TIGR02074 262 IDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFV-YAAALEKGLT-PATIVNDEPITYNGngpWSPKNYGGGYR 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 500 NVVTTRYALENSLNLSTLRLYSGIQDRKPWELLQKMNFNIPKseQENLSLALGATDITLENNVDGFSTLANKGNYQESYM 579
Cdd:TIGR02074 340 GNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPL--DPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHG 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 580 IESIKTRDGKVIYQHNARPVRIYSPETAYITTDMLRGVLDTGSGY--QLKGTFMynqdwAGKTGTAQEGKDSLFIGYNPK 657
Cdd:TIGR02074 418 IRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRsaRLPGRPV-----AGKTGTTQNWRDAWFVGYTPY 492
|
570 580 590
....*....|....*....|....*....|....*..
gi 1409089500 658 VTMGIWMGYDVPTSFD---EENHYQLRLWRDIINQIT 691
Cdd:TIGR02074 493 YVTAVWVGYDDKKTLGksgTGGGLAAPIWRDFMAEAL 529
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
99-289 |
6.82e-71 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 230.10 E-value: 6.82e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 99 GETLGTLnADVQREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTN 178
Cdd:pfam00912 2 GTLLAEL-GEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 179 ETSFKRKAKEMMLSFKVEKSLSKKEIIEAYLNVVSFGRntngqNIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYT 258
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGR-----GAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSR 155
|
170 180 190
....*....|....*....|....*....|.
gi 1409089500 259 YTPFlqtgefkkdKDLKFGFERQQYVLMRMY 289
Cdd:pfam00912 156 YNPL---------RNPERAKRRRNLVLDRMV 177
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
110-667 |
5.09e-50 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 188.52 E-value: 5.09e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 110 QREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEM 189
Cdd:PRK14850 156 KRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEI 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 190 MLSFKVEKSLSKKEIIEAYLNVVSFGRNTNGQnIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgefk 269
Cdd:PRK14850 236 YMALILDRFYSKDRILELYLNEVYLGQDGNEQ-IRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPW------- 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 270 kdKDLKFGFERQQYVLMRMYQEKKITKAQYEQAKkfnlkksftkdfevpnekypfltqeveSRAIDIlkyifAEKDNISR 349
Cdd:PRK14850 308 --TNPNLTLKRRNLVLFLLYKQKVITRKLYKDLC---------------------------SRPLNV-----QSKGNIIS 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 350 QELDETPVLQEKYVGIANRAIRNNGYIidttihkKIFDTMDQIKDNPnyysyARNANVNG------KTKAINMEVGVLLK 423
Cdd:PRK14850 354 SHPAFIQLVCEEFHKKIHYPFKNFSGT-------KIFTTLDYISQNA-----AEQAVKIGipilkrKKRLKDLEVAMVII 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 424 ENDSGKILSFIGGRNHNDSQNNHATKTKRSPGSTIKPlLTYAPAI----EYGITA--PEAALLDKQFNYNGYSPENYARM 497
Cdd:PRK14850 422 DRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKP-ITYLTALsqpeKYHLNTwiSDTPISIKLDNGQYWTPKNNNFS 500
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 498 EYNVVTTRYALENSLNLSTLRLYSGIQDRK---PWELL---QKMNFNIPkseqenlSLALGATDITLENNVDGFSTLANK 571
Cdd:PRK14850 501 FSGKVMLIDALIHSINIPTVHLSINLGLKKlvdSWILLgisSNYITPLP-------SISLGAINLTPMEVAQVFQIIGSG 573
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 572 GNYQESYMIESIKTRDGKVIYQHNARPVRIYSPETAYITTDMLRGVLDTGSGYQLkGTFMYNQDWAGKTGTAQEGKDSLF 651
Cdd:PRK14850 574 GYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKSL-GTIFKEFSLAGKTGTTNNLVDSWF 652
|
570
....*....|....*.
gi 1409089500 652 IGYNPKVTMGIWMGYD 667
Cdd:PRK14850 653 VGIDGKQVVITWIGRD 668
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
65-725 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 563.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 65 YFLALVKDEPVKNNTalkkSLYEMTQSTTVYFGTGETLGTLnADVQREVIKYNKMSPHVIDALIATEDENFYKHNGIVPK 144
Cdd:COG0744 33 LVALYVADLPDPEEL----EDLALPQTSTIYDRDGTLIATL-GDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 145 AFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEMMLSFKVEKSLSKKEIIEAYLNVVSFGRNtngqnIA 224
Cdd:COG0744 108 GIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG-----AY 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 225 GVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgefkkdKDLKFGFERQQYVLMRMYQEKKITKAQYEQAKK 304
Cdd:COG0744 183 GIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPY---------RNPEAAKERRNLVLDRMVEQGYITQAEADAAKA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 305 FNLKKSFTKDfEVPNEKYPFLTQEVESRAIDIlkyiFAEKDnisrqeldetpvlqekyvgianraIRNNGYIIDTTIHKK 384
Cdd:COG0744 254 EPLTLVPPPN-GAAAGKYPYFVDYVRRELEEL----LGEDD------------------------LYRGGLKIYTTLDPK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 385 IFDTMDQIkdnpnyysyARNANVNGKTKaiNMEVGVLLKENDSGKILSFIGGRNHNDSQNNHATKTKRSPGSTIKPLlTY 464
Cdd:COG0744 305 LQKAAEKA---------VKNVLPEGKPG--GLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPF-VY 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 465 APAIEYGITaPEAALLDKQFNYNG--YSPENYARMEYNVVTTRYALENSLNLSTLRLYSGIQDRKPWELLQKMNfnIPKS 542
Cdd:COG0744 373 AAALEQGYT-PATTVDDEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLG--ITSP 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 543 EQENLSLALGATDITLENNVDGFSTLANKGNYQESYMIESIKTRDGKVIYQHNARPVRIYSPETAYITTDMLRGVLDTGS 622
Cdd:COG0744 450 LDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGT 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 623 GYQLKgtfMYNQDWAGKTGTAQEGKDSLFIGYNPKVTMGIWMGYD--VPTSFDEENHYQLRLWRDIINQIttqdqLQMGV 700
Cdd:COG0744 530 GRAAR---LPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDdnSPMGYVTGGSLPAPIWRDFMEAA-----LEGLP 601
|
650 660
....*....|....*....|....*
gi 1409089500 701 GERFNQPDDVKKIemCQYSMSQKGS 725
Cdd:COG0744 602 VEDFPKPSGVVRI--DEPSPTPSGT 624
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
110-691 |
7.50e-147 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 441.31 E-value: 7.50e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 110 QREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEM 189
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 190 MLSFKVEKSLSKKEIIEAYLNVVSFGRNTNGqniagVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgefk 269
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYG-----IEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPF------- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 270 kdKDLKFGFERQQYVLMRMYQEKKITKAQYEQAKK--FNLKKSFTKDFEVpneKYPFLTQEVesraidilkyifaekdni 347
Cdd:TIGR02074 149 --KNPERAKDRRNLVLSNMVENGYITAEEAEEAINepIQLYLQTKKSEQY---KAPYFVDYV------------------ 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 348 sRQELDEtpvlqekyvgIANRAIRNNGYIIDTTIhkkifdtmdqikdNPNYYSYARNANVNGKTKAINM-----EVGVLL 422
Cdd:TIGR02074 206 -IQELEE----------EYGEELYTGGLKIYTTL-------------DLDAQKAAEKVLNTGLRVAGRRdgddlQAALVA 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 423 KENDSGKILSFIGGRNHNDSQNNHATKTKRSPGSTIKPLLtYAPAIEYGITaPEAALLDKQFNYNG---YSPENYARMEY 499
Cdd:TIGR02074 262 IDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFV-YAAALEKGLT-PATIVNDEPITYNGngpWSPKNYGGGYR 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 500 NVVTTRYALENSLNLSTLRLYSGIQDRKPWELLQKMNFNIPKseQENLSLALGATDITLENNVDGFSTLANKGNYQESYM 579
Cdd:TIGR02074 340 GNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPL--DPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHG 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 580 IESIKTRDGKVIYQHNARPVRIYSPETAYITTDMLRGVLDTGSGY--QLKGTFMynqdwAGKTGTAQEGKDSLFIGYNPK 657
Cdd:TIGR02074 418 IRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRsaRLPGRPV-----AGKTGTTQNWRDAWFVGYTPY 492
|
570 580 590
....*....|....*....|....*....|....*..
gi 1409089500 658 VTMGIWMGYDVPTSFD---EENHYQLRLWRDIINQIT 691
Cdd:TIGR02074 493 YVTAVWVGYDDKKTLGksgTGGGLAAPIWRDFMAEAL 529
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
86-671 |
6.41e-135 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 419.18 E-value: 6.41e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 86 YEMTQSTTVYFGTGETLGTLnADVQREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGST 165
Cdd:COG5009 42 YQPPTPSRVYSADGKLIAEF-GEERRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGST 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 166 LTQQLIKNQLLTNETSFKRKAKEMMLSFKVEKSLSKKEIIEAYLNVVSFGRNTNgqniaGVQAAAQGIFGVDANKLNVAQ 245
Cdd:COG5009 121 ITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAY-----GVAAAAQTYFGKSLDELTLAE 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 246 AAYIAGMPQNPYTYTPFlqtgefkkdKDLKFGFERQQYVLMRMYQEKKITKAQYEQAKKFNLK-KSFTKDFEVPNekyPF 324
Cdd:COG5009 196 AAMLAGLPKAPSRYNPI---------RNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTaRYHGASAEVDA---PY 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 325 LTQEVESRAIDILKYIFAEKDNIS-RQELDetPVLQEkyvgIANRAIRNNGYIID---------TTIHKKIFDTMDQIKD 394
Cdd:COG5009 264 FAEMVRRELVERYGEDALYTGGLKvYTTLD--PRLQE----AAEKALRDGLLAYDrrhgyrgpeAHLDLAEEDWDEALAE 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 395 NPNYYSY---------ARNANV---NGKTKAINME--------------------VGVLLKEND---------------- 426
Cdd:COG5009 338 VPDVGDLrpavvlevdDKSARVglrDGETGTLPLEglkwarpyindnrrgpapksASDVLKPGDvirvrpvadggwrlrq 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 427 --------------SGKILSFIGGRNHNDSQNNHATKTKRSPGSTIKPLLtYAPAIEYGITaPEAALLDKQFNYNG---- 488
Cdd:COG5009 418 ipevqgalvaldphTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFV-YAAALDNGYT-PATIINDAPIVFDDgggg 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 489 --YSPENYARMEYNVVTTRYALENSLNLSTLRLysgIQD---RKPWELLQKMNF--NIPKseqeNLSLALGATDITLENN 561
Cdd:COG5009 496 gvWRPKNYSGKFYGPTTLREALEKSRNLVTVRL---LQDvgiDYVIDYAERFGIysKLPP----NLSLALGSGEVTPLEM 568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 562 VDGFSTLANKGNYQESYMIESIKTRDGKVIYQHNA---------------------RPVRIYSPETAYITTDMLRGVLDT 620
Cdd:COG5009 569 ARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADParacedcdaaewdgaeprlpdPAEQVIDPRTAYQMTSMLRGVVQR 648
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 1409089500 621 GSGYQLKGTfmyNQDWAGKTGTAQEGKDSLFIGYNPKVTMGIWMGYDVPTS 671
Cdd:COG5009 649 GTGRRARAL---GRDIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPRS 696
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
85-719 |
3.40e-80 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 273.63 E-value: 3.40e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 85 LYEMTQSTTVYFGTGETLG-TLNADVQ-REVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSG 162
Cdd:COG4953 37 LFAVPYSTVVLDRDGTLLRaFLAADGQwRLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 163 GSTLTQQLIKnqLLT-NETSFKRKAKEMMLSFKVEKSLSKKEIIEAYLNVVSFGRntngqNIAGVQAAAQGIFGVDANKL 241
Cdd:COG4953 117 GSTLTMQVAR--LLEpRPRTLSGKLRQILRALQLERRYSKDEILELYLNLAPYGG-----NIEGVEAASLAYFGKPPSRL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 242 NVAQAAYIAGMPQNPYTYTPFLQTGEFKKdkdlkfgfeRQQYVLMRMYQEKKITKAQYEQAKkfnlkksftkdfevpNEK 321
Cdd:COG4953 190 SLAEAALLAVLPQAPSRRRPDRNPERARA---------ARDRVLARLAEAGVIDAEEAALAL---------------LEP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 322 YPFLTQEVESRAIdilkyIFAEKdnisrqeldetpVLQEkyvgianraiRNNGYIIDTTIHKKIFDTM-DQIKDnpnyys 400
Cdd:COG4953 246 VPARRRPLPQLAP-----HLARR------------LLRQ----------LPGGTRIRTTLDAGLQRRLeRLVRR------ 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 401 YARNANVNGKTKAinmevGVLLKENDSGKILSFIGGRNHNDSQNNHA---TKTKRSPGSTIKPLLtYAPAIEYGITAPEA 477
Cdd:COG4953 293 YVRRLKQNGIHNA-----AVLVVDNRTGEVLAYVGSADFFDASRQGQvdmVRALRSPGSTLKPFL-YGLALDQGLIHPET 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 478 ALLDKQFNYNGYSPENYARMEYNVVTTRYALENSLNLSTLRLysgIQDRKPWEL---LQKMNFN--IPKSEQENLSLALG 552
Cdd:COG4953 367 LLADVPTSFGGYRPENFDGTFQGPVSAREALARSLNIPAVRL---LEALGPARFyarLRRAGLRllLPPAEHYGLSLILG 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 553 ATDITLENNVDGFSTLANKGNYQESYMiesikTRDGKViyqhnARPVRIYSPETAYITTDMLRGVLDTGSGYqlkGTFMY 632
Cdd:COG4953 444 GAEVTLEELVGLYAALARGGEARPLRL-----LAGEPA-----SPGRRLLSPGAAWLVRDILSDVPRPDGAF---GWRAL 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 633 NQDW--AGKTGTAQEGKDSLFIGYNPKVTMGIWMGydvptSFDEENHYQL-------RLWRDIINQITTQdqlqmGVGER 703
Cdd:COG4953 511 DSPPpiAWKTGTSYGFRDAWAVGFTGRYTVGVWVG-----NPDGTPVPGLtgaeaaaPLLFDIFDLLPAS-----RWPLP 580
|
650
....*....|....*.
gi 1409089500 704 FNQPDDVKKIEMCQYS 719
Cdd:COG4953 581 FPPPAGLLRVEVCAPS 596
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
99-289 |
6.82e-71 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 230.10 E-value: 6.82e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 99 GETLGTLnADVQREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTN 178
Cdd:pfam00912 2 GTLLAEL-GEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 179 ETSFKRKAKEMMLSFKVEKSLSKKEIIEAYLNVVSFGRntngqNIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYT 258
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGR-----GAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSR 155
|
170 180 190
....*....|....*....|....*....|.
gi 1409089500 259 YTPFlqtgefkkdKDLKFGFERQQYVLMRMY 289
Cdd:pfam00912 156 YNPL---------RNPERAKRRRNLVLDRMV 177
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
110-667 |
5.09e-50 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 188.52 E-value: 5.09e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 110 QREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEM 189
Cdd:PRK14850 156 KRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEI 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 190 MLSFKVEKSLSKKEIIEAYLNVVSFGRNTNGQnIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgefk 269
Cdd:PRK14850 236 YMALILDRFYSKDRILELYLNEVYLGQDGNEQ-IRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPW------- 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 270 kdKDLKFGFERQQYVLMRMYQEKKITKAQYEQAKkfnlkksftkdfevpnekypfltqeveSRAIDIlkyifAEKDNISR 349
Cdd:PRK14850 308 --TNPNLTLKRRNLVLFLLYKQKVITRKLYKDLC---------------------------SRPLNV-----QSKGNIIS 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 350 QELDETPVLQEKYVGIANRAIRNNGYIidttihkKIFDTMDQIKDNPnyysyARNANVNG------KTKAINMEVGVLLK 423
Cdd:PRK14850 354 SHPAFIQLVCEEFHKKIHYPFKNFSGT-------KIFTTLDYISQNA-----AEQAVKIGipilkrKKRLKDLEVAMVII 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 424 ENDSGKILSFIGGRNHNDSQNNHATKTKRSPGSTIKPlLTYAPAI----EYGITA--PEAALLDKQFNYNGYSPENYARM 497
Cdd:PRK14850 422 DRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKP-ITYLTALsqpeKYHLNTwiSDTPISIKLDNGQYWTPKNNNFS 500
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 498 EYNVVTTRYALENSLNLSTLRLYSGIQDRK---PWELL---QKMNFNIPkseqenlSLALGATDITLENNVDGFSTLANK 571
Cdd:PRK14850 501 FSGKVMLIDALIHSINIPTVHLSINLGLKKlvdSWILLgisSNYITPLP-------SISLGAINLTPMEVAQVFQIIGSG 573
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 572 GNYQESYMIESIKTRDGKVIYQHNARPVRIYSPETAYITTDMLRGVLDTGSGYQLkGTFMYNQDWAGKTGTAQEGKDSLF 651
Cdd:PRK14850 574 GYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKSL-GTIFKEFSLAGKTGTTNNLVDSWF 652
|
570
....*....|....*.
gi 1409089500 652 IGYNPKVTMGIWMGYD 667
Cdd:PRK14850 653 VGIDGKQVVITWIGRD 668
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
124-667 |
4.53e-48 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 183.43 E-value: 4.53e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 124 IDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEMMLSFKVEKSLSKKE 203
Cdd:PRK09506 224 VDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 204 IIEAYLNVVSFGRNTNGQnIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgefkkdKDLKFGFERQQY 283
Cdd:PRK09506 304 ILELYLNEVYLGQSGDDQ-IRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPW---------RNPKLALERRNL 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 284 VLMRMYQEKKITKAQYEQAKKFNLKKSFTKDFEVPNekyPFLTQEVesraidilkyifaekdnisRQEldetpvLQEKyv 363
Cdd:PRK09506 374 VLRLLQQQQIIDQELYDMLSARPLGVQPKGGVISPQ---PAFMQMV-------------------RQE------LQAK-- 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 364 gIANRAIRNNGYiidttihkKIFDTMDQIKDNPnyysyARNANVNG-----KTKAIN-MEVGVLLKENDSGKILSFIGGR 437
Cdd:PRK09506 424 -LGDKVKDLSGV--------KIFTTLDPVSQDA-----AEKAVEEGipalkKQRKLSdLETAMVVVDRFSGEVRAMVGGS 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 438 NHNDSQNNHATKTKRSPGSTIKPlLTYAPAI----EYGITA--PEAALLDKQFNYNGYSPENYARMEYNVVTTRYALENS 511
Cdd:PRK09506 490 EPQFAGYNRAMQARRSIGSLAKP-ATYLTALsqpdKYRLNTwiADAPISLRQPNGQVWSPQNDDRRFSGRVMLVDALTRS 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 512 LNLSTLRLYSGIQDRKPWELLQKMnfNIPKSE-QENLSLALGATDITLENNVDGFSTLANKGNYQESYMIESIKTRDGKV 590
Cdd:PRK09506 569 MNVPTVNLGMALGLPAVTDTWIKL--GVPKDQlNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKV 646
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1409089500 591 IYQHNARPVRIYSPETAYITTDMLRGVLDTGSGYQLKGTFMyNQDWAGKTGTAQEGKDSLFIGYNPKVTMGIWMGYD 667
Cdd:PRK09506 647 LYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKYP-NLHLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRD 722
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
114-667 |
6.31e-45 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 173.78 E-value: 6.31e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 114 IKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSFKRKAKEMMLSF 193
Cdd:PRK11636 69 LTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAI 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 194 KVEKSLSKKEIIEAYLNVVSFgrntnGQNIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTPFlqtgeFKKDKD 273
Cdd:PRK11636 149 RIEQLLTKDEILELYLNKIYL-----GYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPL-----YSMDRA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 274 LKfgfeRQQYVLMRMYQEKKITKAQYEQAKKFNLkksfTKDFEVPNEKY--PFLTQEVESRAIDilKYifaeKDNISRQE 351
Cdd:PRK11636 219 VA----RRNVVLSRMLDEGYITQAQYDQARSEPI----VANYHAPEIAFsaPYLSEMVRQEMYN--RY----GENAYEDG 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 352 LDETPVLQEKYVGIANRAIRNN--------GYIIDTTI----------HKKIFDTMdqiKDNPNY---------YSYARN 404
Cdd:PRK11636 285 YRVYTTITRKVQQAAQQAVRNNvldydmrhGYRGPANVlwkvgesawdNKKITDTL---KALPTYgpllpavvtSANPQE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 405 ANV---NGKTKAINMEvGV------------------------------LLKENDS--------------------GKIL 431
Cdd:PRK11636 362 ATAmlaDGSSVALPME-GVrwarpyrsdtqqgptprkvtdvvqtgqqiwVRQVDDAwwlaqvpdvnsalvsinpqnGAVM 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 432 SFIGGRNHNDSQNNHATKTKRSPGSTIKPLLtYAPAIEYGITApeAALLD---------------KQFNyngySPENYAr 496
Cdd:PRK11636 441 ALVGGFDFNQSKFNRATQALRQVGSNIKPFL-YTAAMDKGLTL--ASMLNdvpisrwdagagsdwRPKN----SPPQYA- 512
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 497 meyNVVTTRYALENSLNLSTLRLYSGIQDRKPWELLQKMNF---NIPKSEqenlSLALGATDITLENNVDGFSTLANKGN 573
Cdd:PRK11636 513 ---GPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFpaqNIVHTE----SLALGSASFTPMQVARGYAVMANGGF 585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 574 YQESYMIESIKTRDGKVIYQHNAR--------PVrIY--SPETAYITTD------------------------------- 612
Cdd:PRK11636 586 LVDPYFISKIENDQGGVIFEAKPKvacpecdiPV-IYgdTQKSNVLENDdvenvatsqeqqnssvpmpqleqanqalvaq 664
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 613 -----------------MLRGVLDT---------GSGYQlKGTFMYNQDWAGKTGTAQEGKDSLFIGYNPKVTMGIWMGY 666
Cdd:PRK11636 665 ngaqeyaphvintplafLIKSALNTnifgepgwmGTGWR-AGRDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGF 743
|
.
gi 1409089500 667 D 667
Cdd:PRK11636 744 D 744
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
120-665 |
8.15e-29 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 123.27 E-value: 8.15e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 120 SPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKnqLLT-NETSFKRKAKEMMLSFKVEKS 198
Cdd:PRK11240 71 SPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR--LLDpHPRTFGGKIRQLWRALQLEWH 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 199 LSKKEIIEAYLNVVSFgrntnGQNIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTP--FLQTGEFKKDKdlkf 276
Cdd:PRK11240 149 LSKREILTLYLNRAPF-----GGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPdrWPERAEAARNK---- 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 277 gferqqyVLMRMYQEKKITKAQYEQAKKFNLkksftkdFEVPnekypfltqevesraidilkyifaekdnisRQELDETP 356
Cdd:PRK11240 220 -------VLERMAEQGVWSAEQVKESREEPV-------WLAP------------------------------RQMPQLAP 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 357 VLQEKyvgiANRAIRNNgyIIDTTIHKKIFDTMDQIKDNPNYYSYARNAnvngktkainmeVGVLLKENDSGKILSFIGG 436
Cdd:PRK11240 256 LFARM----MLGKSKSD--KIVTTLDAGLQRRLEDLALNWKGRLPPRSS------------LAMIVVDHTDMAVRGWVGS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 437 RNHND-SQNNHA--TKTKRSPGSTIKPLLtYAPAIEYGITAPEAALLDKQFNYNGYSPENYARMEYNVVTTRYALENSLN 513
Cdd:PRK11240 318 VDLNDdSRFGHVdmVNAIRSPGSVLKPFV-YGLALDDGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSEALVRSLN 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 514 LSTLRLYSGIQDRKPWELLQK--MNFNIPKSEQENLSLALGATDITLENNVDGFSTLANKGnyqesymiesiKTRDGKVI 591
Cdd:PRK11240 397 LPAVQVLEAYGPKRFAAKLRNvgLPLYLPAGAEPNLSLILGGAGARLEDMVAAYSAFARHG-----------KAAKLRLQ 465
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1409089500 592 YQHNARPVRIYSPETAYITtdmlRGVLDTGSGYQLKGTFMYNQDWAGKTGTAQEGKDSLFIGYNPKVTMGIWMG 665
Cdd:PRK11240 466 PDDPLLERPLMSPGAAWII----RRIMADEAQPLPDAALPRVVPLAWKTGTSYGYRDAWAIGVNARYVIGIWTG 535
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
103-290 |
2.56e-28 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 113.71 E-value: 2.56e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 103 GTLNADVQREVIKYNKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVTSGGSTLTQQLIKNQLLTNETSF 182
Cdd:TIGR02070 47 GDPTCGIQHRWRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSY 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 183 KRKAKEMMLSFKVEKSLSKKEIIEAYLNVVSFGrntNGqnIAGVQAAAQGIFGVDANKLNVAQAAYIAGMPQNPYTYTpf 262
Cdd:TIGR02070 127 LRKGLEAWATWMLETWWSKQRILEVYLNSVEWG---NG--VFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYD-- 199
|
170 180
....*....|....*....|....*...
gi 1409089500 263 lqtgEFKKDKDLKFgfeRQQYVLMRMYQ 290
Cdd:TIGR02070 200 ----ENRPGPYVRR---KATWILKQMGY 220
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
117-302 |
1.28e-23 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 100.26 E-value: 1.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 117 NKMSPHVIDALIATEDENFYKHNGIVPKAFIRATAQEFLNMGVtSGGSTLTQQLIKNQLLTNETSFKRKAKEMMLSFKVE 196
Cdd:PRK13481 51 DNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDV-QGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVE 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 197 KSLSKKEIIEAYLNVVSFgrntnGQNIAGVQAAAQGIFGVDANKLN-------VAQAAYIAGMPQNPYTYTPFLQTGEFK 269
Cdd:PRK13481 130 KQYSKNEILSFYLNNIYF-----GDNQYTLEGAANHYFGTTVNKNSttmshitVLQSAILASKVNAPSVYNINDMSENFT 204
|
170 180 190
....*....|....*....|....*....|...
gi 1409089500 270 kdkdlkfgfERQQYVLMRMYQEKKITKAQYEQA 302
Cdd:PRK13481 205 ---------QRVSTNLEKMKQQNYINETQYQQA 228
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
419-662 |
1.02e-16 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 81.69 E-value: 1.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 419 GVLLKENDSGKILSFIGGRNHNDSQ-----NNHATKTKRSPGSTIKPlLTYAPAIEYGITAPeaallDKQFNYNGYSPEN 493
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYDPNGfigplRNRAVTSRYEPGSTFKP-FTALAALDNGVLKP-----DETIFDWPGKQQG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 494 YARME------YNVVTTRYALENSLN---------LSTLRLYSGIQD-----RKPWELLQKMNFNIPKSEQENLSLALGA 553
Cdd:pfam00905 76 GKSIGdwnqdqVGIGTLRQALEYSSNwymqklaqkLGADKLRSYLKKfgygnKTGIGLPGENAGYLTPYWLEGATASFGI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 554 TD-ITLENNVDGFSTLANKGNYQESYMIESIKTRDGKViyQHNARPVriySPETAYITTDMLRGVLDTGSGYQLKGTFMY 632
Cdd:pfam00905 156 GLtITPLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPK--VLNKLPI---SKSTAEKVKDMLRLVVNDGTGTGTAAVPGY 230
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1409089500 633 nqDWAGKTGTAQ-----------EGKDSLFIGY----NPKVTMGI 662
Cdd:pfam00905 231 --KVAGKTGTAQvagpkgggyydGAQIGWFVGYapadNPKYAFAV 273
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
454-660 |
3.77e-16 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 82.56 E-value: 3.77e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 454 PGSTIKPLLTYApAIEYGITAPEAALLDK-QFNYNGYSPENYARMEYNVVTTRYALENSLNLSTLRLYSGIQDRKPWELL 532
Cdd:COG0768 294 PGSTFKPFTAAA-ALEEGVITPDTTFDCPgYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYL 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 533 QKMNF--------------NIPKSEQ----ENLSLALG----ATDITLennVDGFSTLANKGNYQESYMIESIKTRDGKV 590
Cdd:COG0768 373 KKFGLgqktgidlpgeasgLLPSPKRwypgETATMSIGqglsVTPLQL---AQAYAAIANGGVLVKPHLVKEIVDPDGEV 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 591 IYQHNARPVRIYSPETAYITTDMLRGVLD----TGSGYQLKGtfmYNQdwAGKTGTAQ-----EGKD------SLFIGY- 654
Cdd:COG0768 450 VKEEPEVLRRVISPETAETVREGMEGVVNepggTARRAAIPG---YRV--AGKTGTAQvvdigNGGYykgrhiASFVGFa 524
|
....*....
gi 1409089500 655 ---NPKVTM 660
Cdd:COG0768 525 padNPRYAV 533
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
566-659 |
7.08e-05 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 46.36 E-value: 7.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1409089500 566 STLANKGNYQESYMIESIKTRDGKVIYQHNARPVRI--YSPETAYITTDMLRGVLDT--GSGYQLKGTFMYnqDWAGKTG 641
Cdd:TIGR03423 446 AALANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPlpISPENLDVVREGMRDVVNGpgGTARRARLGLPY--KMAGKTG 523
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1409089500 642 TAQ-----------------EGKD-SLFIGY----NPKVT 659
Cdd:TIGR03423 524 TAQvvslkqgekydaeqipeRLRDhALFVAFapydNPKIA 563
|
|
| |
