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Conserved domains on  [gi|1391255445|ref|WP_109396065|]
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AraC family transcriptional regulator [Proteus faecis]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 13307529)

AraC family transcriptional regulator controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
184-266 8.30e-28

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 102.63  E-value: 8.30e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  184 KWHLEDVAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTP 262
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 1391255445  263 SQFR 266
Cdd:smart00342  81 SEYR 84
PRK15186 super family cl33102
AraC family transcriptional regulator; Provisional
 19-265 1.79e-16

AraC family transcriptional regulator; Provisional


The actual alignment was detected with superfamily member PRK15186:

Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 77.80  E-value: 1.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  19 IENPMIAMVSGAKGTICINGQSIDVSSHLTLIIPKYSQVScdIVNQFTHKSIELHTLVLCETELQSVFSL-LKPLIKSSS 97
Cdd:PRK15186   37 LQSVLIKLTTGKISITTSSGEYITASGPMLIFLAKDQTIH--ITMEETHEQLNYNLIELDSASIKNAYNFfLYEHADFSA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  98 PLTSHLPAYHLSTPEViksnfGILKqCLPLPHGSPSQETMFM--QQCLFFILMAVYQEGIDILNIFRFNYDEPKNQAITH 175
Cdd:PRK15186  115 PLTKPTTKHLLAPIET-----GVAR-VFNLLHSSNKSQKLSQdkKEYLIRFLLSEFIYEPEAFALFRELSQNTLAENIYN 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 176 LITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFK 255
Cdd:PRK15186  189 IIISDISRKWALKDISDSLYMSCSTLKRKLKQENTSFSEVYLNARMNKATKLLRNSEYNITRVAYMCGYDSASYFTCVFK 268

                         250
                  ....*....|
gi 1391255445 256 RKYGMTPSQF 265
Cdd:PRK15186  269 KHFKTTPSEF 278
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
184-266 8.30e-28

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 102.63  E-value: 8.30e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  184 KWHLEDVAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTP 262
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 1391255445  263 SQFR 266
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
187-273 3.57e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.92  E-value: 3.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 187 LEDVAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQF 265
Cdd:COG2207   171 LEELARELGLSPRTLSRLFKEEtGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEY 250


                  ....*...
gi 1391255445 266 RTQSRQSN 273
Cdd:COG2207   251 RKRLRARA 258
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 173-265 1.56e-18

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 83.89  E-value: 1.56e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 173 ITHLITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCD 252
Cdd:PRK15185  211 VYNIISSSPSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDSTSYFIQ 290

                          90
                  ....*....|...
gi 1391255445 253 AFKRKYGMTPSQF 265
Cdd:PRK15185  291 CFKKYFKTTPSTF 303
HTH_18 pfam12833
Helix-turn-helix domain;
190-268 4.55e-18

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 76.86  E-value: 4.55e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 190 VAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLT-FSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRT 267
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLeDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 1391255445 268 Q 268
Cdd:pfam12833  81 R 81
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 19-265 1.79e-16

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 77.80  E-value: 1.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  19 IENPMIAMVSGAKGTICINGQSIDVSSHLTLIIPKYSQVScdIVNQFTHKSIELHTLVLCETELQSVFSL-LKPLIKSSS 97
Cdd:PRK15186   37 LQSVLIKLTTGKISITTSSGEYITASGPMLIFLAKDQTIH--ITMEETHEQLNYNLIELDSASIKNAYNFfLYEHADFSA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  98 PLTSHLPAYHLSTPEViksnfGILKqCLPLPHGSPSQETMFM--QQCLFFILMAVYQEGIDILNIFRFNYDEPKNQAITH 175
Cdd:PRK15186  115 PLTKPTTKHLLAPIET-----GVAR-VFNLLHSSNKSQKLSQdkKEYLIRFLLSEFIYEPEAFALFRELSQNTLAENIYN 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 176 LITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFK 255
Cdd:PRK15186  189 IIISDISRKWALKDISDSLYMSCSTLKRKLKQENTSFSEVYLNARMNKATKLLRNSEYNITRVAYMCGYDSASYFTCVFK 268

                         250
                  ....*....|
gi 1391255445 256 RKYGMTPSQF 265
Cdd:PRK15186  269 KHFKTTPSEF 278
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
184-266 8.30e-28

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 102.63  E-value: 8.30e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  184 KWHLEDVAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTP 262
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 1391255445  263 SQFR 266
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
187-273 3.57e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.92  E-value: 3.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 187 LEDVAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQF 265
Cdd:COG2207   171 LEELARELGLSPRTLSRLFKEEtGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEY 250


                  ....*...
gi 1391255445 266 RTQSRQSN 273
Cdd:COG2207   251 RKRLRARA 258
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 173-265 1.56e-18

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 83.89  E-value: 1.56e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 173 ITHLITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCD 252
Cdd:PRK15185  211 VYNIISSSPSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDSTSYFIQ 290

                          90
                  ....*....|...
gi 1391255445 253 AFKRKYGMTPSQF 265
Cdd:PRK15185  291 CFKKYFKTTPSTF 303
HTH_18 pfam12833
Helix-turn-helix domain;
190-268 4.55e-18

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 76.86  E-value: 4.55e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 190 VAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLT-FSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRT 267
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLeDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 1391255445 268 Q 268
Cdd:pfam12833  81 R 81
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 19-265 1.79e-16

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 77.80  E-value: 1.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  19 IENPMIAMVSGAKGTICINGQSIDVSSHLTLIIPKYSQVScdIVNQFTHKSIELHTLVLCETELQSVFSL-LKPLIKSSS 97
Cdd:PRK15186   37 LQSVLIKLTTGKISITTSSGEYITASGPMLIFLAKDQTIH--ITMEETHEQLNYNLIELDSASIKNAYNFfLYEHADFSA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  98 PLTSHLPAYHLSTPEViksnfGILKqCLPLPHGSPSQETMFM--QQCLFFILMAVYQEGIDILNIFRFNYDEPKNQAITH 175
Cdd:PRK15186  115 PLTKPTTKHLLAPIET-----GVAR-VFNLLHSSNKSQKLSQdkKEYLIRFLLSEFIYEPEAFALFRELSQNTLAENIYN 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 176 LITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFK 255
Cdd:PRK15186  189 IIISDISRKWALKDISDSLYMSCSTLKRKLKQENTSFSEVYLNARMNKATKLLRNSEYNITRVAYMCGYDSASYFTCVFK 268

                         250
                  ....*....|
gi 1391255445 256 RKYGMTPSQF 265
Cdd:PRK15186  269 KHFKTTPSEF 278
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 83-274 4.07e-16

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 76.50  E-value: 4.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445  83 QSVFSLLKPLIKSSSpLTSHLPAYHlSTPEVIKS--NFGILKQCLPLPHGSP-SQETMFMQQCLFFILMAVYQEGID--- 156
Cdd:PRK09978   56 RDTLSLFLPMLKEEA-LNLHAHKKV-SSLLVHHCsrDIPVFQEVAQLSQNKNlRYAEMLRKRALIFALLSVFLEDEHfip 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 157 -ILNIFRFNYDEPKNQAITHLITQDpqrkWHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNYTV 235
Cdd:PRK09978  134 lLLNVLQPNMRTRVCTVINNNIAHE----WTLARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSI 209

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1391255445 236 FQISHRCGFGSNAYFCDAFKRKYGMTPSQFRTQSRQSND 274
Cdd:PRK09978  210 KRVAVSCGYHSVSYFIYVFRNYYGMTPTEYQERSAQGLP 248
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 171-282 6.80e-16

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 77.02  E-value: 6.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 171 QAITHLITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLTfSNYTVFQISHRCGFGSNAY 249
Cdd:COG2169    87 ARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHtGVTPKAYARARRLLRARQLLQ-TGLSVTDAAYAAGFGSLSR 165

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1391255445 250 FCDAFKRKYGMTPSQFRTQSRQSNDPSAITKLS 282
Cdd:COG2169   166 FYEAFKKLLGMTPSAYRRGGAGAAIRFAPTPCS 198
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 171-270 2.41e-14

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 72.11  E-value: 2.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 171 QAITHLITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAY 249
Cdd:COG4977   213 ARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAAtGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASH 292

                          90       100
                  ....*....|....*....|.
gi 1391255445 250 FCDAFKRKYGMTPSQFRTQSR 270
Cdd:COG4977   293 FRRAFRRRFGVSPSAYRRRFR 313
PRK15044 PRK15044
transcriptional regulator SirC; Provisional
 171-265 7.02e-13

transcriptional regulator SirC; Provisional


Pssm-ID: 185004 [Multi-domain]  Cd Length: 295  Bit Score: 67.75  E-value: 7.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 171 QAITHLITQDPQRKWHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYF 250
Cdd:PRK15044  195 EKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAGNISQVATMCGYDTPSYF 274

                          90
                  ....*....|....*
gi 1391255445 251 CDAFKRKYGMTPSQF 265
Cdd:PRK15044  275 IAIFKRHFKITPLSF 289
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 185-270 1.05e-10

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 60.87  E-value: 1.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 185 WHLEDVAKTLFTTPSTLRRHLSKEGVSFCQLLLDVRMGIALNYLTFSNyTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQ 264
Cdd:PRK09940  151 WKLKDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEG-SVNKIAEQCGYASTSYFIYAFRKHFGNSPKR 229


                  ....*.
gi 1391255445 265 FRTQSR 270
Cdd:PRK09940  230 VSKEYR 235
ftrA PRK09393
transcriptional activator FtrA; Provisional
 177-270 3.15e-07

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 50.73  E-value: 3.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 177 ITQDPQRKWHLEDVAKTLFTTPSTLRRHLSK-EGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFK 255
Cdd:PRK09393  227 MRAHLAEPHTVASLAARAAMSPRTFLRRFEAaTGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGSEESLRHHFR 306

                          90
                  ....*....|....*
gi 1391255445 256 RKYGMTPSQFRTQSR 270
Cdd:PRK09393  307 RRAATSPAAYRKRFG 321
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
187-274 6.24e-07

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 49.97  E-value: 6.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 187 LEDVAKTLFTTPSTLRrHLSKE--GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQ 264
Cdd:PRK10572  202 IESVAQHVCLSPSRLA-HLFRQqlGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFKKCTGASPSE 280

                          90
                  ....*....|
gi 1391255445 265 FRTQSRQSND 274
Cdd:PRK10572  281 FRARCEEKNN 290
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
201-272 6.46e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 49.67  E-value: 6.46e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1391255445 201 LRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRTQSRQS 272
Cdd:PRK13502  209 LRQQFRAQtGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTPSQWRHLSNQS 281
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 231-267 4.74e-06

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 42.91  E-value: 4.74e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1391255445 231 SNYTVFQISHRCGFGSNaYFCDAFKRKYGMTPSQFRT 267
Cdd:pfam00165   7 TNLTIADIADELGFSRS-YFSRLFKKYTGVTPSQYRH 42
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
201-273 2.12e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 45.48  E-value: 2.12e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1391255445 201 LRRHLSKE-GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRTQSRQSN 273
Cdd:PRK13500  239 LRQQFRQQtGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD 312
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 201-270 4.31e-05

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 44.25  E-value: 4.31e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1391255445 201 LRRHLSKEGVSFCQLLLDVRMGIALNYLT--FSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRTQSR 270
Cdd:PRK09685  231 LYRLFAEQGLVVAQYIRNRRLDRCADDLRpaADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRKFR 302
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
209-272 9.31e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 43.35  E-value: 9.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1391255445 209 GVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRTQSRQS 272
Cdd:PRK13501  218 GMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQRFIRS 281
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
200-268 1.07e-03

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 40.05  E-value: 1.07e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 200 TLRRHL-SKEGVSFCQLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRTQ 268
Cdd:PRK13503  203 TLHRQLkQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSPRDIRQG 272
PRK10296 PRK10296
DNA-binding transcriptional regulator ChbR; Provisional
 214-273 1.00e-02

DNA-binding transcriptional regulator ChbR; Provisional


Pssm-ID: 182362 [Multi-domain]  Cd Length: 278  Bit Score: 37.04  E-value: 1.00e-02
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391255445 214 QLLLDVRMGIALNYLTFSNYTVFQISHRCGFGSNAYFCDAFKRKYGMTPSQFRTQSRQSN 273
Cdd:PRK10296  219 QIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPGSYRKKLTEFN 278
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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