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Conserved domains on  [gi|1374313122|ref|WP_107282595|]
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MULTISPECIES: phasin family protein [Photobacterium]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Phasin super family cl07863
Poly(hydroxyalcanoate) granule associated protein (phasin); Polyhydroxyalkanoates (PHAs) are ...
 8-117 8.83e-08

Poly(hydroxyalcanoate) granule associated protein (phasin); Polyhydroxyalkanoates (PHAs) are storage polyesters synthesized by various bacteria as intracellular carbon and energy reserve material. PHAs are accumulated as water-insoluble inclusions within the cells. This family consists of the phasins PhaF and PhaI which act as a transcriptional regulator of PHA biosynthesis genes. PhaF has been proposed to repress expression of the phaC1 gene and the phaIF operon.


The actual alignment was detected with superfamily member pfam05597:

Pssm-ID: 447545  Cd Length: 126  Bit Score: 46.86  E-value: 8.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374313122   8 KAAKNVVESGEGVARNIWLAGLGLYSRTLEEAQQLnektstaFDELVERGKEVETQAKECIGQNAEKASDEVEAGMNDLF 87
Cdd:pfam05597   2 KQAEQLAGEVKDSARQIWLAGLGAFAKAQEEGGKL-------FEALVKEGEELEKRTRKVAEEQLEEVRERVESMVEDVK 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1374313122  88 YRLSG----------------------VDREKLERMDEKIDKLTLAVEKLAE 117
Cdd:pfam05597  75 ARATGqwdkleqafdervaralnrlgvPSRKDVEALSARVDELTAELERLTG 126
 
Name Accession Description Interval E-value
Phasin pfam05597
Poly(hydroxyalcanoate) granule associated protein (phasin); Polyhydroxyalkanoates (PHAs) are ...
 8-117 8.83e-08

Poly(hydroxyalcanoate) granule associated protein (phasin); Polyhydroxyalkanoates (PHAs) are storage polyesters synthesized by various bacteria as intracellular carbon and energy reserve material. PHAs are accumulated as water-insoluble inclusions within the cells. This family consists of the phasins PhaF and PhaI which act as a transcriptional regulator of PHA biosynthesis genes. PhaF has been proposed to repress expression of the phaC1 gene and the phaIF operon.


Pssm-ID: 428533  Cd Length: 126  Bit Score: 46.86  E-value: 8.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374313122   8 KAAKNVVESGEGVARNIWLAGLGLYSRTLEEAQQLnektstaFDELVERGKEVETQAKECIGQNAEKASDEVEAGMNDLF 87
Cdd:pfam05597   2 KQAEQLAGEVKDSARQIWLAGLGAFAKAQEEGGKL-------FEALVKEGEELEKRTRKVAEEQLEEVRERVESMVEDVK 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1374313122  88 YRLSG----------------------VDREKLERMDEKIDKLTLAVEKLAE 117
Cdd:pfam05597  75 ARATGqwdkleqafdervaralnrlgvPSRKDVEALSARVDELTAELERLTG 126
PHA_granule_1 TIGR01837
poly(hydroxyalkanoate) granule-associated protein; This model describes a domain found in some ...
 18-116 6.16e-07

poly(hydroxyalkanoate) granule-associated protein; This model describes a domain found in some proteins associated with polyhydroxyalkanoate (PHA) granules in a subset of species that have PHA inclusion granules. Included are two tandem proteins of Pseudomonas oleovorans, PhaI and PhaF, and their homologs in related species. PhaF proteins have a low-complexity C-terminal region with repeats similar to AAAKP. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 130896  Cd Length: 118  Bit Score: 44.75  E-value: 6.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374313122  18 EGVARNIWLAGLGLYSRTLEEAQQLnektstaFDELVERGKEVETQAKECIGQNAEKASDEVE----------------- 80
Cdd:TIGR01837   3 GESARKVWLAGIGALARVQEEGSKF-------FNRLVKEGELAEKRGQKRFDESVDAAREEVKtaleqtrdqvqrnwdkl 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1374313122  81 -----AGMNDLFYRLSGVDREKLERMDEKIDKLTLAVEKLA 116
Cdd:TIGR01837  76 ekafdERVEQALNRLNIPSREEIEALSAKIEQLAVQVEELR 116
PhaF COG3937
Polyhydroxyalkanoate synthesis regulator phasin [Secondary metabolites biosynthesis, transport ...
 21-119 4.00e-06

Polyhydroxyalkanoate synthesis regulator phasin [Secondary metabolites biosynthesis, transport and catabolism, Signal transduction mechanisms];


Pssm-ID: 443138 [Multi-domain]  Cd Length: 103  Bit Score: 42.09  E-value: 4.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374313122  21 ARNIWLAGLGLYSRTLEEAQQLnektstaFDELVERGKEVETQAKECI-------GQNAEKASDEVEAGMNDLFYRLSGV 93
Cdd:COG3937     5 LKKLLLAGLGAASLTKEKAEEL-------VDELVEKGELTEEEAKKFVdelvekgEEEKEELEEKIEEQVEEALEKLGLA 77

                          90       100
                  ....*....|....*....|....*.
gi 1374313122  94 DREKLERMDEKIDKLTLAVEKLAEVE 119
Cdd:COG3937    78 TKEEVDELEERIDRLEKQLRELENKK 103
 
Name Accession Description Interval E-value
Phasin pfam05597
Poly(hydroxyalcanoate) granule associated protein (phasin); Polyhydroxyalkanoates (PHAs) are ...
 8-117 8.83e-08

Poly(hydroxyalcanoate) granule associated protein (phasin); Polyhydroxyalkanoates (PHAs) are storage polyesters synthesized by various bacteria as intracellular carbon and energy reserve material. PHAs are accumulated as water-insoluble inclusions within the cells. This family consists of the phasins PhaF and PhaI which act as a transcriptional regulator of PHA biosynthesis genes. PhaF has been proposed to repress expression of the phaC1 gene and the phaIF operon.


Pssm-ID: 428533  Cd Length: 126  Bit Score: 46.86  E-value: 8.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374313122   8 KAAKNVVESGEGVARNIWLAGLGLYSRTLEEAQQLnektstaFDELVERGKEVETQAKECIGQNAEKASDEVEAGMNDLF 87
Cdd:pfam05597   2 KQAEQLAGEVKDSARQIWLAGLGAFAKAQEEGGKL-------FEALVKEGEELEKRTRKVAEEQLEEVRERVESMVEDVK 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1374313122  88 YRLSG----------------------VDREKLERMDEKIDKLTLAVEKLAE 117
Cdd:pfam05597  75 ARATGqwdkleqafdervaralnrlgvPSRKDVEALSARVDELTAELERLTG 126
PHA_granule_1 TIGR01837
poly(hydroxyalkanoate) granule-associated protein; This model describes a domain found in some ...
 18-116 6.16e-07

poly(hydroxyalkanoate) granule-associated protein; This model describes a domain found in some proteins associated with polyhydroxyalkanoate (PHA) granules in a subset of species that have PHA inclusion granules. Included are two tandem proteins of Pseudomonas oleovorans, PhaI and PhaF, and their homologs in related species. PhaF proteins have a low-complexity C-terminal region with repeats similar to AAAKP. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 130896  Cd Length: 118  Bit Score: 44.75  E-value: 6.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374313122  18 EGVARNIWLAGLGLYSRTLEEAQQLnektstaFDELVERGKEVETQAKECIGQNAEKASDEVE----------------- 80
Cdd:TIGR01837   3 GESARKVWLAGIGALARVQEEGSKF-------FNRLVKEGELAEKRGQKRFDESVDAAREEVKtaleqtrdqvqrnwdkl 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1374313122  81 -----AGMNDLFYRLSGVDREKLERMDEKIDKLTLAVEKLA 116
Cdd:TIGR01837  76 ekafdERVEQALNRLNIPSREEIEALSAKIEQLAVQVEELR 116
PhaF COG3937
Polyhydroxyalkanoate synthesis regulator phasin [Secondary metabolites biosynthesis, transport ...
 21-119 4.00e-06

Polyhydroxyalkanoate synthesis regulator phasin [Secondary metabolites biosynthesis, transport and catabolism, Signal transduction mechanisms];


Pssm-ID: 443138 [Multi-domain]  Cd Length: 103  Bit Score: 42.09  E-value: 4.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374313122  21 ARNIWLAGLGLYSRTLEEAQQLnektstaFDELVERGKEVETQAKECI-------GQNAEKASDEVEAGMNDLFYRLSGV 93
Cdd:COG3937     5 LKKLLLAGLGAASLTKEKAEEL-------VDELVEKGELTEEEAKKFVdelvekgEEEKEELEEKIEEQVEEALEKLGLA 77

                          90       100
                  ....*....|....*....|....*.
gi 1374313122  94 DREKLERMDEKIDKLTLAVEKLAEVE 119
Cdd:COG3937    78 TKEEVDELEERIDRLEKQLRELENKK 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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