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Conserved domains on  [gi|1361084054|ref|WP_106284162|]
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MULTISPECIES: shikimate kinase [Paraburkholderia]

Protein Classification

shikimate kinase( domain architecture ID 11478131)

shikimate kinase catalyzes the specific phosphorylation of the 3-hydroxylgroup of shikimic acid using ATP as a cosubstrate

CATH:  3.40.50.300
EC:  2.7.1.71
Gene Ontology:  GO:0008652|GO:0009073|GO:0004765|GO:0000287|GO:0005524
PubMed:  2279393|7870841
SCOP:  4003925

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
aroK PRK00131
shikimate kinase; Reviewed
 7-176 1.15e-93

shikimate kinase; Reviewed


:

Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 269.75  E-value: 1.15e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   7 HANVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGG 86
Cdd:PRK00131    4 GPNIVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARHNLVISTGGG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  87 AILRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNGLVN 166
Cdd:PRK00131   84 AVLREENRALLRERGTVVYLDASFEELLRRLRRDRNRPLLQTNDPKEKLRDLYEERDPLYEEVADITVETDGRSPEEVVN 163

                         170
                  ....*....|
gi 1361084054 167 MVLMQLEMAG 176
Cdd:PRK00131  164 EILEKLEAAW 173
 
Name Accession Description Interval E-value
aroK PRK00131
shikimate kinase; Reviewed
 7-176 1.15e-93

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 269.75  E-value: 1.15e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   7 HANVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGG 86
Cdd:PRK00131    4 GPNIVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARHNLVISTGGG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  87 AILRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNGLVN 166
Cdd:PRK00131   84 AVLREENRALLRERGTVVYLDASFEELLRRLRRDRNRPLLQTNDPKEKLRDLYEERDPLYEEVADITVETDGRSPEEVVN 163

                         170
                  ....*....|
gi 1361084054 167 MVLMQLEMAG 176
Cdd:PRK00131  164 EILEKLEAAW 173
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 10-173 1.73e-82

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 241.19  E-value: 1.73e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAIL 89
Cdd:COG0703     1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEEENAVIATGGGAVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  90 RPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNGLVNMVL 169
Cdd:COG0703    81 SPENRELLKEHGTVVYLDASPETLLERLRRDDNRPLLQGEDPRERLEELLAEREPLYREVADITVDTDGRSPEEVVDEIL 160


                  ....
gi 1361084054 170 MQLE 173
Cdd:COG0703   161 EALE 164
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 9-161 1.11e-70

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 210.87  E-value: 1.11e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAI 88
Cdd:cd00464     1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEREVLLLLLTKENAVIATGGGAV 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1361084054  89 LRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKaRLEALYEVRDPLYRECAHFVIETGRPSV 161
Cdd:cd00464    81 LREENRRLLLENGIVVWLDASPEELLERLARDKTRPLLQDEDPE-RLRELLEEREPLYREVADLTIDTDELSP 152
SKI pfam01202
Shikimate kinase;
16-173 2.56e-65

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 197.42  E-value: 2.56e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  16 MGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAILRPENRE 95
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEHGLVIATGGGAVLSEENRD 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1361084054  96 ALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDP-KARLEALYEVRDPLYRECAHFVIETGRPSVNGLVNMVLMQLE 173
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKRDKTRPLLQNKDPeEELLELLFEERDPLYEEAADIVIDTDESSPEEVATEILEALE 159
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 9-106 7.85e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 35.43  E-value: 7.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054    9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDsdheieartgaripvIFELEGEAGFREREASVISDLTGRDniVLATGGGAI 88
Cdd:smart00382   4 VILIVGPPGSGKTTLARALARELGPPGGG---------------VIYIDGEDILEEVLDQLLLIIVGGK--KASGSGELR 66

                           90
                   ....*....|....*...
gi 1361084054   89 LRPENREALQNRGVVIYL 106
Cdd:smart00382  67 LRLALALARKLKPDVLIL 84
 
Name Accession Description Interval E-value
aroK PRK00131
shikimate kinase; Reviewed
 7-176 1.15e-93

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 269.75  E-value: 1.15e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   7 HANVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGG 86
Cdd:PRK00131    4 GPNIVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARHNLVISTGGG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  87 AILRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNGLVN 166
Cdd:PRK00131   84 AVLREENRALLRERGTVVYLDASFEELLRRLRRDRNRPLLQTNDPKEKLRDLYEERDPLYEEVADITVETDGRSPEEVVN 163

                         170
                  ....*....|
gi 1361084054 167 MVLMQLEMAG 176
Cdd:PRK00131  164 EILEKLEAAW 173
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 10-173 1.73e-82

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 241.19  E-value: 1.73e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAIL 89
Cdd:COG0703     1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEEENAVIATGGGAVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  90 RPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNGLVNMVL 169
Cdd:COG0703    81 SPENRELLKEHGTVVYLDASPETLLERLRRDDNRPLLQGEDPRERLEELLAEREPLYREVADITVDTDGRSPEEVVDEIL 160


                  ....
gi 1361084054 170 MQLE 173
Cdd:COG0703   161 EALE 164
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 9-161 1.11e-70

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 210.87  E-value: 1.11e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAI 88
Cdd:cd00464     1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEREVLLLLLTKENAVIATGGGAV 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1361084054  89 LRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKaRLEALYEVRDPLYRECAHFVIETGRPSV 161
Cdd:cd00464    81 LREENRRLLLENGIVVWLDASPEELLERLARDKTRPLLQDEDPE-RLRELLEEREPLYREVADLTIDTDELSP 152
aroK PRK05057
shikimate kinase AroK;
9-174 4.06e-70

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 209.95  E-value: 4.06e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAI 88
Cdd:PRK05057    6 NIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADIGWVFDVEGEEGFRDREEKVINELTEKQGIVLATGGGSV 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  89 LRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNGLVNMV 168
Cdd:PRK05057   86 KSRETRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQVDDPREVLEALANERNPLYEEIADVTIRTDDQSAKVVANQI 165


                  ....*.
gi 1361084054 169 LMQLEM 174
Cdd:PRK05057  166 IHMLES 171
SKI pfam01202
Shikimate kinase;
16-173 2.56e-65

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 197.42  E-value: 2.56e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  16 MGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAILRPENRE 95
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEHGLVIATGGGAVLSEENRD 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1361084054  96 ALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDP-KARLEALYEVRDPLYRECAHFVIETGRPSVNGLVNMVLMQLE 173
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKRDKTRPLLQNKDPeEELLELLFEERDPLYEEAADIVIDTDESSPEEVATEILEALE 159
PRK13946 PRK13946
shikimate kinase; Provisional
 7-169 7.81e-53

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 166.64  E-value: 7.81e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   7 HANVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGG 86
Cdd:PRK13946   10 KRTVVLVGLMGAGKSTVGRRLATMLGLPFLDADTEIERAARMTIAEIFAAYGEPEFRDLERRVIARLLKGGPLVLATGGG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  87 AILRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYREcAHFVIETGRPSVNGLVN 166
Cdd:PRK13946   90 AFMNEETRAAIAEKGISVWLKADLDVLWERVSRRDTRPLLRTADPKETLARLMEERYPVYAE-ADLTVASRDVPKEVMAD 168


                  ...
gi 1361084054 167 MVL 169
Cdd:PRK13946  169 EVI 171
PRK13947 PRK13947
shikimate kinase; Provisional
 9-169 2.80e-45

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 147.16  E-value: 2.80e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAI 88
Cdd:PRK13947    3 NIVLIGFMGTGKTTVGKRVATTLSFGFIDTDKEIEKMTGMTVAEIFEKDGEVRFRSEEKLLVKKLARLKNLVIATGGGVV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  89 LRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDPKARLEALYEVRDPLYReCAHFVIETGRPSVNGLVNMV 168
Cdd:PRK13947   83 LNPENVVQLRKNGVVICLKARPEVILRRVGKKKSRPLLMVGDPEERIKELLKEREPFYD-FADYTIDTGDMTIDEVAEEI 161


                  .
gi 1361084054 169 L 169
Cdd:PRK13947  162 I 162
PRK13948 PRK13948
shikimate kinase; Provisional
 10-160 1.87e-40

shikimate kinase; Provisional


Pssm-ID: 184413 [Multi-domain]  Cd Length: 182  Bit Score: 134.92  E-value: 1.87e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAIL 89
Cdd:PRK13948   13 VALAGFMGTGKSRIGWELSRALMLHFIDTDRYIERVTGKSIPEIFRHLGEAYFRRCEAEVVRRLTRLDYAVISLGGGTFM 92

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1361084054  90 RPENREALQNRGVVIYLRANPHDLWLRTRRDKnRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPS 160
Cdd:PRK13948   93 HEENRRKLLSRGPVVVLWASPETIYERTRPGD-RPLLQVEDPLGRIRTLLNEREPVYRQATIHVSTDGRRS 162
aroL PRK03731
shikimate kinase AroL;
10-159 1.64e-37

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 126.98  E-value: 1.64e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTgRDNIVLATGGGAIL 89
Cdd:PRK03731    5 LFLVGARGCGKTTVGMALAQALGYRFVDTDQWLQSTSNMTVAEIVEREGWAGFRARESAALEAVT-APSTVIATGGGIIL 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1361084054  90 RPENREALQNRGVVIYLRANPHDLWLRTRRDKN---RPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRP 159
Cdd:PRK03731   84 TEENRHFMRNNGIVIYLCAPVSVLANRLEANPEedqRPTLTGKPISEEVAEVLAEREALYREVAHHIIDATQP 156
PRK13951 PRK13951
bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;
10-148 4.25e-32

bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;


Pssm-ID: 172457 [Multi-domain]  Cd Length: 488  Bit Score: 120.01  E-value: 4.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAIL 89
Cdd:PRK13951    3 IFLVGMMGSGKSTIGKRVSEVLDLQFIDMDEEIERREGRSVRRIFEEDGEEYFRLKEKELLRELVERDNVVVATGGGVVI 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1361084054  90 RPENREALQNRGvVIYLRANPHDLWLRTRRDkNRPLLQteDPKARLEALYEVRDPLYRE 148
Cdd:PRK13951   83 DPENRELLKKEK-TLFLYAPPEVLMERVTTE-NRPLLR--EGKERIREIWERRKQFYTE 137
PRK13949 PRK13949
shikimate kinase; Provisional
 7-153 3.44e-31

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 110.97  E-value: 3.44e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   7 HANVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGG 86
Cdd:PRK13949    1 MARIFLVGYMGAGKTTLGKALARELGLSFIDLDFFIENRFHKTVGDIFAERGEAVFRELERNMLHEVAEFEDVVISTGGG 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1361084054  87 AILRPENREALQNRGVVIYLRANPHDLWLRTRRDK-NRPLLQTEDPKARL----EALyEVRDPLYRECAHFV 153
Cdd:PRK13949   81 APCFFDNMELMNASGTTVYLKVSPEVLFVRLRLAKqQRPLLKGKSDEELLdfiiEAL-EKRAPFYRQAKIIF 151
PRK14021 PRK14021
bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional
 13-156 1.64e-30

bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional


Pssm-ID: 184458 [Multi-domain]  Cd Length: 542  Bit Score: 116.11  E-value: 1.64e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  13 VGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGAILRPE 92
Cdd:PRK14021   12 IGMMGAGKTRVGKEVAQMMRLPFADADVEIEREIGMSIPSYFEEYGEPAFREVEADVVADMLEDFDGIFSLGGGAPMTPS 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1361084054  93 NREALQNR----GVVIYLRANPHDLWLRTRRDKNRPLLqTEDPKARLEALYEVRDPLYRECAHFVIET 156
Cdd:PRK14021   92 TQHALASYiahgGRVVYLDADPKEAMERANRGGGRPML-NGDANKRWKKLFKQRDPVFRQVANVHVHT 158
PLN02199 PLN02199
shikimate kinase
 9-146 8.71e-23

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 92.45  E-value: 8.71e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIE-ARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGGGA 87
Cdd:PLN02199  104 SMYLVGMMGSGKTTVGKLMSKVLGYTFFDCDTLIEqAMNGTSVAEIFVHHGENFFRGKETDALKKLSSRYQVVVSTGGGA 183

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1361084054  88 ILRPENREALqNRGVVIYLRANPHDLWLRTRR--DKNRPLLQTEDPKA------RLEALYEVRDPLY 146
Cdd:PLN02199  184 VIRPINWKYM-HKGISIWLDVPLEALAHRIAAvgTDSRPLLHDESGDAysvafkRLSAIWDERGEAY 249
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 13-168 1.99e-19

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 83.46  E-value: 1.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  13 VGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEAGFREREASVISDLTGR-DNIVLATGGGAILRP 91
Cdd:PRK08154  139 IGLRGAGKSTLGRMLAARLGVPFVELNREIEREAGLSVSEIFALYGQEGYRRLERRALERLIAEhEEMVLATGGGIVSEP 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  92 ENREALQNRGVVIYLRANPHDLWLRTRRDKN-RPLLQTEDPKARLEALYEVRDPLYREcAHFVIET-GRP---SVNGLVN 166
Cdd:PRK08154  219 ATFDLLLSHCYTVWLKASPEEHMARVRAQGDlRPMADNREAMEDLRRILASREPLYAR-ADAVVDTsGLTvaqSLARLRE 297


                  ..
gi 1361084054 167 MV 168
Cdd:PRK08154  298 LV 299
PRK00625 PRK00625
shikimate kinase; Provisional
 9-106 1.58e-15

shikimate kinase; Provisional


Pssm-ID: 134335 [Multi-domain]  Cd Length: 173  Bit Score: 70.56  E-value: 1.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054   9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIP----VIFELEGEAGFREREASVISDLTgRDNIVLATG 84
Cdd:PRK00625    2 QIFLCGLPTVGKTSFGKALAKFLSLPFFDTDDLIVSNYHGALYsspkEIYQAYGEEGFCREEFLALTSLP-VIPSIVALG 80

                          90       100
                  ....*....|....*....|..
gi 1361084054  85 GGAILRPENREALQNRGVVIYL 106
Cdd:PRK00625   81 GGTLMIEPSYAHIRNRGLLVLL 102
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
10-159 2.01e-08

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 51.07  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPvifELEGEAGFREREASVISDLTGRdniVLATGGGAIL 89
Cdd:COG0645     2 ILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFGAGLA---PLERSPEATARTYARLLALARE---LLAAGRSVIL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  90 -----RPENREAL----QNRGV---VIYLRANPHDLWLR-TRRDKNRPllqteDPKARLEAL----YEVRDPLYRECAHF 152
Cdd:COG0645    76 datflRRAQREAFralaEEAGApfvLIWLDAPEEVLRERlEARNAEGG-----DSDATWEVLerqlAFEEPLTEDEGFLL 150


                  ....*..
gi 1361084054 153 VIETGRP 159
Cdd:COG0645   151 VVDTSGL 157
PRK09169 PRK09169
hypothetical protein; Validated
 3-131 1.38e-06

hypothetical protein; Validated


Pssm-ID: 236394 [Multi-domain]  Cd Length: 2316  Bit Score: 47.79  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054    3 ARDAHANVFFVGLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEGEagFREREASVISDLTgRDNIVLA 82
Cdd:PRK09169  2106 ERLGAQARRIEREVGPLLQALLQKLAGGLRVDKPHSVRKIAKKIGKKIARIQALRGL--SPEQAAARVRDAL-RWEVVLP 2182

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1361084054   83 TGGGAILRPENREALQNRGVVIYLRANPHDLWLRTRRDKNRPLLQTEDP 131
Cdd:PRK09169  2183 AEGFGAAVEQARQALGAKGLRVMRINNGFAAPDTTYAGLNVNLRTAAGL 2231
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 14-39 4.62e-05

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 41.65  E-value: 4.62e-05
                          10        20
                  ....*....|....*....|....*.
gi 1361084054  14 GLMGAGKTTVGRAIARRLDRPFFDSD 39
Cdd:COG3265     8 GVSGSGKSTVGQALAERLGWPFIDGD 33
AAA_18 pfam13238
AAA domain;
10-124 1.92e-04

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 39.33  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRLDRPFFDSD----HEIEARTGARIPVIFELEGEAGFREREASVISDLTGRDNIVLATGG 85
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDlaleNGLVLGDDPETRESKRLDEDKLDRLLDLLEENAALEEGGNLIIDGH 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1361084054  86 GAILRPENREalqnRGVVIYLRANPHDLWLRTR-RDKNRP 124
Cdd:pfam13238  81 LAELEPERAK----DLVGIVLRASPEELLERLEkRGYEEA 116
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 14-39 3.48e-04

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 39.16  E-value: 3.48e-04
                          10        20
                  ....*....|....*....|....*.
gi 1361084054  14 GLMGAGKTTVGRAIARRLDRPFFDSD 39
Cdd:cd02021     6 GVSGSGKSTVGKALAERLGAPFIDGD 31
RecA-like_Lon cd19500
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ...
 12-36 8.06e-04

lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410908 [Multi-domain]  Cd Length: 182  Bit Score: 38.31  E-value: 8.06e-04
                          10        20
                  ....*....|....*....|....*
gi 1361084054  12 FVGLMGAGKTTVGRAIARRLDRPFF 36
Cdd:cd19500    42 LVGPPGVGKTSLGKSIARALGRKFV 66
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 13-89 1.22e-03

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 38.14  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  13 VGLM---GAGKTTVGRAIARrLDRPffDSDheiEARTGARIPVIFELeGeAGFRereasviSDLTGRDNIVLatgGGAIL 89
Cdd:COG1134    55 VGIIgrnGAGKSTLLKLIAG-ILEP--TSG---RVEVNGRVSALLEL-G-AGFH-------PELTGRENIYL---NGRLL 116
APSK cd02027
Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5 ...
 10-31 2.60e-03

Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of inorganic sulfate.


Pssm-ID: 238985 [Multi-domain]  Cd Length: 149  Bit Score: 36.69  E-value: 2.60e-03
                          10        20
                  ....*....|....*....|..
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRL 31
Cdd:cd02027     2 IWLTGLSGSGKSTIARALEEKL 23
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 10-31 3.63e-03

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 36.61  E-value: 3.63e-03
                          10        20
                  ....*....|....*....|..
gi 1361084054  10 VFFVGLMGAGKTTVGRAIARRL 31
Cdd:COG0529    19 VWFTGLSGSGKSTLANALERRL 40
PRK06217 PRK06217
hypothetical protein; Validated
 14-123 4.14e-03

hypothetical protein; Validated


Pssm-ID: 168472  Cd Length: 183  Bit Score: 36.57  E-value: 4.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054  14 GLMGAGKTTVGRAIARRLDRPFFDSDHEIEARTGARIPVIFELEgeagfrEREASVISDLTGRDNIVLAtggGAILR-PE 92
Cdd:PRK06217    8 GASGSGTTTLGAALAERLDIPHLDTDDYFWLPTDPPFTTKRPPE------ERLRLLLEDLRPREGWVLS---GSALGwGD 78

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1361084054  93 NREALQNRGVVIYLranPHDlwLRTRRDKNR 123
Cdd:PRK06217   79 PLEPLFDLVVFLTI---PPE--LRLERLRLR 104
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 14-53 4.80e-03

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 35.93  E-value: 4.80e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1361084054  14 GLMGAGKTTVGRAIARRLDRPFFDS----DHEIE--ARTGARIPVI 53
Cdd:cd02020     6 GPAGSGKSTVAKLLAKKLGLPYLDTggirTEEVGklASEVAAIPEV 51
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 9-106 7.85e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 35.43  E-value: 7.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1361084054    9 NVFFVGLMGAGKTTVGRAIARRLDRPFFDsdheieartgaripvIFELEGEAGFREREASVISDLTGRDniVLATGGGAI 88
Cdd:smart00382   4 VILIVGPPGSGKTTLARALARELGPPGGG---------------VIYIDGEDILEEVLDQLLLIIVGGK--KASGSGELR 66

                           90
                   ....*....|....*...
gi 1361084054   89 LRPENREALQNRGVVIYL 106
Cdd:smart00382  67 LRLALALARKLKPDVLIL 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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