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Conserved domains on  [gi|1341788698|ref|WP_103877088|]
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MULTISPECIES: DNA polymerase III subunit gamma/tau [Petrotoga]

Protein Classification

DnaX/STICHEL family protein( domain architecture ID 11494202)

DnaX/STICHEL family protein similar to Arabidopsis thaliana STICHEL that acts as a key regulator of trichome branching through an endoreduplication-independent pathway and to bacterial DNA polymerase III subunit gamma/tau

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
4-329 4.07e-149

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 428.91  E-value: 4.07e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   4 NLYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINN 83
Cdd:TIGR02397   3 VLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEINS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  84 NSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPD 163
Cdd:TIGR02397  83 GSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 164 TIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLF 243
Cdd:TIGR02397 163 TILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLV 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 244 DENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLI------------------------NEKRSN 299
Cdd:TIGR02397 243 DDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLikktpsnllavleseqeflkelalKLSLEF 322
                         330       340       350
                  ....*....|....*....|....*....|
gi 1341788698 300 LIHLMGIFNNILKDLKYSENKRLIFDVEIL 329
Cdd:TIGR02397 323 LLRLLDILLEALKDLRFSNDPRIWLEMTLL 352
 
Name Accession Description Interval E-value
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
4-329 4.07e-149

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 428.91  E-value: 4.07e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   4 NLYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINN 83
Cdd:TIGR02397   3 VLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEINS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  84 NSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPD 163
Cdd:TIGR02397  83 GSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 164 TIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLF 243
Cdd:TIGR02397 163 TILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLV 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 244 DENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLI------------------------NEKRSN 299
Cdd:TIGR02397 243 DDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLikktpsnllavleseqeflkelalKLSLEF 322
                         330       340       350
                  ....*....|....*....|....*....|
gi 1341788698 300 LIHLMGIFNNILKDLKYSENKRLIFDVEIL 329
Cdd:TIGR02397 323 LLRLLDILLEALKDLRFSNDPRIWLEMTLL 352
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
5-427 1.09e-148

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 432.27  E-value: 1.09e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14962    4 LYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14962   84 TFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPT 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK14962  164 IISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGLIP 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 245 ENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSNLIHLMGIFNNILKDLKYSENKRLIF 324
Cdd:PRK14962  244 IEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLVEDLERERANDIIQVSRQLLNILREIKFAEEKRLVC 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 325 DVEILDFMHKYSTTSVPLLHENEKTPNRNQVTTESVIKETQ-----------HPIMKKILDYFsdphEKKSNMAIYFALL 393
Cdd:PRK14962  324 KLGSASIATRFSSPNVQENDVEEKNDNSNVQQKEKKKEESKakeekqediefEKRFKELMEEL----KEKGDLSIFVALS 399
                         410       420       430
                  ....*....|....*....|....*....|....
gi 1341788698 394 FSNPEIENNKIHFKFSSGQKLEYEILKKYVDELK 427
Cdd:PRK14962  400 LSEVEEDGDKVKISFDSSKAMHYELMKEKLPELE 433
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
11-333 2.42e-140

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 406.11  E-value: 2.42e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  11 PLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDVI 90
Cdd:COG2812     6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVI 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  91 EMDA-ASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRS 169
Cdd:COG2812    86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 170 QIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGemkithqdTLDIlglfdENFIV 249
Cdd:COG2812   166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFG--------LLDR-----RELLL 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 250 QFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFD-----------SLINEKR-------------SNLIHLMG 305
Cdd:COG2812   233 DLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDllllklgpdaeLLVNEDErerlqelarrlspERLLRAIQ 312
                         330       340
                  ....*....|....*....|....*...
gi 1341788698 306 IFNNILKDLKYSENKRLIFDVEILDFMH 333
Cdd:COG2812   313 ILLEARRELERNVNPRLALEMLLLRLAR 340
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
19-177 1.53e-53

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 177.02  E-value: 1.53e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  19 GQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDV--IEMDAAS 96
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLviIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  97 NRgIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKN 176
Cdd:pfam13177  81 IK-IDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  .
gi 1341788698 177 L 177
Cdd:pfam13177 160 L 160
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
179-241 8.56e-19

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 80.24  E-value: 8.56e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341788698 179 QNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILG 241
Cdd:cd18137     3 VEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
40-169 2.15e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.15  E-value: 2.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   40 YIFSGPRGTGKTTTARILAKVLNCMDPQV-YNPCNKCENCVSINNNsfLDVIEMDAASNRGIDEIRNIRDssnyRPVYGK 118
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGViYIDGEDILEEVLDQLL--LIIVGGKKASGSGELRLRLALA----LARKLK 78
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1341788698  119 YKVYIIDEFHMLTREAFNALLKTLEEPPSHV-------VFILATTNLEKVPDTIISRS 169
Cdd:smart00382  79 PDVLILDEITSLLDAEQEALLLLLEELRLLLllkseknLTVILTTNDEKDLGPALLRR 136
 
Name Accession Description Interval E-value
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
4-329 4.07e-149

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 428.91  E-value: 4.07e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   4 NLYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINN 83
Cdd:TIGR02397   3 VLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEINS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  84 NSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPD 163
Cdd:TIGR02397  83 GSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 164 TIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLF 243
Cdd:TIGR02397 163 TILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLV 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 244 DENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLI------------------------NEKRSN 299
Cdd:TIGR02397 243 DDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLikktpsnllavleseqeflkelalKLSLEF 322
                         330       340       350
                  ....*....|....*....|....*....|
gi 1341788698 300 LIHLMGIFNNILKDLKYSENKRLIFDVEIL 329
Cdd:TIGR02397 323 LLRLLDILLEALKDLRFSNDPRIWLEMTLL 352
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
5-427 1.09e-148

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 432.27  E-value: 1.09e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14962    4 LYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14962   84 TFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPT 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK14962  164 IISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGLIP 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 245 ENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSNLIHLMGIFNNILKDLKYSENKRLIF 324
Cdd:PRK14962  244 IEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLVEDLERERANDIIQVSRQLLNILREIKFAEEKRLVC 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 325 DVEILDFMHKYSTTSVPLLHENEKTPNRNQVTTESVIKETQ-----------HPIMKKILDYFsdphEKKSNMAIYFALL 393
Cdd:PRK14962  324 KLGSASIATRFSSPNVQENDVEEKNDNSNVQQKEKKKEESKakeekqediefEKRFKELMEEL----KEKGDLSIFVALS 399
                         410       420       430
                  ....*....|....*....|....*....|....
gi 1341788698 394 FSNPEIENNKIHFKFSSGQKLEYEILKKYVDELK 427
Cdd:PRK14962  400 LSEVEEDGDKVKISFDSSKAMHYELMKEKLPELE 433
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
5-445 1.76e-145

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 426.98  E-value: 1.76e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK05563    6 LYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICKAITNG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK05563   86 SLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHKIPAT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK05563  166 ILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEVTGSVS 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 245 ENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINE-------------------------KRSN 299
Cdd:PRK05563  246 QEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKtspeleildestendelfkelseklDIER 325
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 300 LIHLMGIFNNILKDLKYSENKRLIFDVEILDFMHK------YSTTSVPLLHE-----------------------NEKTP 350
Cdd:PRK05563  326 LYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQaaaspeYDTELEVLLQRveqleqelkqlkaqpvgvapeqkEKKKE 405
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 351 NRNQVTTESVIKETQ-HPIMK---------------KILDYFsdpheKKSNMAIYFALLFSNP-EIENNKIHFKFSSGQK 413
Cdd:PRK05563  406 KKKNKKKKYKVPRGKiYKVLKeatrqdlellknvwgEILESL-----KAQRKSLRALLVNSEPvAASEDTVVLAFEYEIH 480
                         490       500       510
                  ....*....|....*....|....*....|...
gi 1341788698 414 LEYEIL-KKYVDELKVNIFLLIDGSYEITFSLE 445
Cdd:PRK05563  481 FEKAMLdKELNDTIENILSKLLGKSVEIVAVPE 513
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
11-333 2.42e-140

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 406.11  E-value: 2.42e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  11 PLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDVI 90
Cdd:COG2812     6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVI 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  91 EMDA-ASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRS 169
Cdd:COG2812    86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 170 QIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGemkithqdTLDIlglfdENFIV 249
Cdd:COG2812   166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFG--------LLDR-----RELLL 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 250 QFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFD-----------SLINEKR-------------SNLIHLMG 305
Cdd:COG2812   233 DLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDllllklgpdaeLLVNEDErerlqelarrlspERLLRAIQ 312
                         330       340
                  ....*....|....*....|....*...
gi 1341788698 306 IFNNILKDLKYSENKRLIFDVEILDFMH 333
Cdd:COG2812   313 ILLEARRELERNVNPRLALEMLLLRLAR 340
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
7-422 2.71e-124

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 370.69  E-value: 2.71e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   7 RKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSF 86
Cdd:PRK14953    8 RKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  87 LDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTII 166
Cdd:PRK14953   88 PDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTIL 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 167 SRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFDEN 246
Cdd:PRK14953  168 SRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEFLGIVSQE 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 247 FIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSN--------------------LIHLMGI 306
Cdd:PRK14953  248 SVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNILLNKSLKNpeevfqvedfyrklekpleaLLYLEDV 327
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 307 FNNILKDLKYSENKRlIFDVEILDFMHKYSTTSV-PLLHENEKTPNRNQVTTESVIKETQhpimkkILDYFSDPHEKKSN 385
Cdd:PRK14953  328 INKAFSEARTRDPLR-AYELAILKLLYVKDIVPIsELLKEGSKQETKEQPEKKEEEKEEL------DIDKIILQIIKNEG 400
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 1341788698 386 MAIYFALLFSNPEIENNKIHFKFSSGQ----KLEYEILKKY 422
Cdd:PRK14953  401 KIISAILKNAEIKEEEGKITIKVEKSEedtlDLEIKSIKKY 441
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
7-332 2.01e-103

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 315.94  E-value: 2.01e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   7 RKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDP-QVYNPCNKCENCVSINNNS 85
Cdd:PRK06305    9 RKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPtEDQEPCNQCASCKEISSGT 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  86 FLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTI 165
Cdd:PRK06305   89 SLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTI 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 166 ISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFDE 245
Cdd:PRK06305  169 LSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKALGLLSQ 248
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 246 NFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSNLIHLMgifnnilkdLKYSENKRLifd 325
Cdd:PRK06305  249 DSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLTLFFRNILLKQYNKQLSSVA---------TKYSSEQLL--- 316

                  ....*..
gi 1341788698 326 vEILDFM 332
Cdd:PRK06305  317 -EIIDFL 322
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
5-264 2.48e-99

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 309.43  E-value: 2.48e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQ-VYNPCNKCENCVSINN 83
Cdd:PRK14950    6 LYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDpKGRPCGTCEMCRAIAE 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  84 NSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPD 163
Cdd:PRK14950   86 GSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPA 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 164 TIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLF 243
Cdd:PRK14950  166 TILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQSLLGIS 245
                         250       260
                  ....*....|....*....|.
gi 1341788698 244 DENFIVQFIENVSNSKIDEFL 264
Cdd:PRK14950  246 GDEEVKALAEALLAKDLKAAL 266
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
5-253 2.74e-99

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 307.83  E-value: 2.74e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14969    6 LARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEIDSG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14969   86 RFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK14969  166 VLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAMLGAID 245

                  ....*....
gi 1341788698 245 ENFIVQFIE 253
Cdd:PRK14969  246 QDYLFALLE 254
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
5-316 5.62e-97

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 301.95  E-value: 5.62e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK08451    4 LALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSALEN 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK08451   84 RHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPAT 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK08451  164 ILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGLLD 243
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341788698 245 ENFIVQFIENVSNS---KIDEFLVQSEDLfnlgkDPEILLEQSIEYIFDSLINEKRSNLIHLMGIFNNILKDLKY 316
Cdd:PRK08451  244 PSKLEDFFQAILNQdkeKLFELLKELEDY-----EAEMVLDEMMLFLKEKFLSKDSEFSILLYERFFRILSSAKS 313
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
5-281 3.00e-96

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 302.65  E-value: 3.00e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQV--YNPCNKCENCVSIN 82
Cdd:PRK14948    6 LHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLNSDKptPEPCGKCELCRAIA 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  83 NNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVP 162
Cdd:PRK14948   86 AGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTDPQRVL 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 163 DTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEmKITHQDTLDILGL 242
Cdd:PRK14948  166 PTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQLSLLPG-PITPEAVWDLLGA 244
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1341788698 243 FDENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILL 281
Cdd:PRK14948  245 VPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAIL 283
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
7-276 3.30e-95

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 299.77  E-value: 3.30e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   7 RKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQV-YNPCNKCENCVSINNNS 85
Cdd:PRK14971    9 RKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNLTAdGEACNECESCVAFNEQR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  86 FLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTI 165
Cdd:PRK14971   89 SYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTI 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 166 ISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFDE 245
Cdd:PRK14971  169 LSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIENLNILDY 248
                         250       260       270
                  ....*....|....*....|....*....|.
gi 1341788698 246 NFIVQFIENVSNSKIDEFLVQSEDLFNLGKD 276
Cdd:PRK14971  249 DYYFRLTDALLAGKVSDSLLLFDEILNKGFD 279
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
5-249 6.05e-95

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 297.81  E-value: 6.05e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNC---MDPQvynPCNKCENCVSI 81
Cdd:PRK14965    6 LARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCeqgLTAE---PCNVCPPCVEI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  82 NNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKV 161
Cdd:PRK14965   83 TEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKV 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 162 PDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILG 241
Cdd:PRK14965  163 PITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAELLG 242

                  ....*...
gi 1341788698 242 LFDENFIV 249
Cdd:PRK14965  243 VVDRRLLL 250
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
5-362 3.77e-94

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 299.81  E-value: 3.77e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCM-DPQVYNPCNKCENcvSINN 83
Cdd:PRK07133    8 LYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCShKTDLLEPCQECIE--NVNN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  84 NsfLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPD 163
Cdd:PRK07133   86 S--LDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIPL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 164 TIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLF 243
Cdd:PRK07133  164 TILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEELFGLV 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 244 DENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSNLIHLMGIFNNILKDLKYSenkrli 323
Cdd:PRK07133  244 SNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIFNKTKDNSLLEYYSEEDLEKLKID------ 317
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1341788698 324 fdveiLDFMHKYSTTSVPLLHENEKTPNRNQVTTESVIK 362
Cdd:PRK07133  318 -----DDFAYKFIEILFDLLKDLKISDNPNDTLEILIIK 351
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
5-281 5.01e-92

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 291.03  E-value: 5.01e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQV-----YNPCNKCENCV 79
Cdd:PRK09111   14 LARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGPDGdggptIDLCGVGEHCQ 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  80 SINNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLE 159
Cdd:PRK09111   94 AIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTEIR 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 160 KVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDI 239
Cdd:PRK09111  174 KVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAVRDM 253
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1341788698 240 LGLFDENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILL 281
Cdd:PRK09111  254 LGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVL 295
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
5-253 1.48e-91

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 292.55  E-value: 1.48e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYN-----PCNKCENCV 79
Cdd:PRK12323    6 LARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADGEGgitaqPCGQCRACT 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  80 SINNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLE 159
Cdd:PRK12323   86 EIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQ 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 160 KVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDI 239
Cdd:PRK12323  166 KIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEEAVRGM 245
                         250
                  ....*....|....
gi 1341788698 240 LGLFDENFIVQFIE 253
Cdd:PRK12323  246 LGAIDQSYLVRLLD 259
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
5-270 2.93e-90

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 289.30  E-value: 2.93e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK08691    6 LARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK08691   86 RYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK08691  166 VLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQMIGAVD 245
                         250       260
                  ....*....|....*....|....*.
gi 1341788698 245 ENFIVQFIENVSNSKIDEFLVQSEDL 270
Cdd:PRK08691  246 KQYLYELLTGIINQDGAALLAKAQEM 271
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
5-253 5.69e-90

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 286.23  E-value: 5.69e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQ-----VYNPCNKCENCV 79
Cdd:PRK14951    6 LARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGPDgqggiTATPCGVCQACR 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  80 SINNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLE 159
Cdd:PRK14951   86 DIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQ 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 160 KVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDI 239
Cdd:PRK14951  166 KVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEAAVRQM 245
                         250
                  ....*....|....
gi 1341788698 240 LGLFDENFIVQFIE 253
Cdd:PRK14951  246 LGSVDRSHVFRLID 259
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
5-244 1.40e-89

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 285.99  E-value: 1.40e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK07994    6 LARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCREIEQG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK07994   86 RFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK07994  166 ILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAMLGTLD 245
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
5-242 2.61e-87

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 275.95  E-value: 2.61e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCM--DPQvynPCNKCENCVSIN 82
Cdd:PRK14963    4 LYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCSgeDPK---PCGECESCLAVR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  83 NNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVP 162
Cdd:PRK14963   81 RGAHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMP 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 163 DTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGeMKITHQDTLDILGL 242
Cdd:PRK14963  161 PTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALG-TPVTRKQVEEALGL 239
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-325 2.70e-86

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 276.34  E-value: 2.70e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   1 MNNNLYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVS 80
Cdd:PRK05896    2 SEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCES 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  81 INNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEK 160
Cdd:PRK05896   82 INTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQK 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 161 VPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDIL 240
Cdd:PRK05896  162 IPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKTF 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 241 GLFDENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSNLIHLMGIFNNILKDLKYSENK 320
Cdd:PRK05896  242 GLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVYQKTKNINLLKKLSKEQLKTLNLEKQK 321

                  ....*
gi 1341788698 321 RLIFD 325
Cdd:PRK05896  322 LLSIE 326
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
4-282 2.39e-85

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 270.50  E-value: 2.39e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   4 NLYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINN 83
Cdd:PRK14964    2 NLALKYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  84 NSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPD 163
Cdd:PRK14964   82 SNHPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 164 TIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLF 243
Cdd:PRK14964  162 TIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCV 241
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1341788698 244 DENFIVQFIENVSNSKIDEFLVQSEDLFNLGkDPEILLE 282
Cdd:PRK14964  242 DKHILEDLVEAILLGDAQSALNVFRELCNTS-NPVIILE 279
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
8-287 8.84e-85

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 271.26  E-value: 8.84e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   8 KYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFL 87
Cdd:PRK06647    9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCKSIDNDNSL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  88 DVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIIS 167
Cdd:PRK06647   89 DVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKS 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 168 RSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFDENF 247
Cdd:PRK06647  169 RCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSKMGLTGDEF 248
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1341788698 248 IVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEY 287
Cdd:PRK06647  249 LEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEF 288
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
7-301 1.31e-84

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 272.20  E-value: 1.31e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   7 RKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCM----DPQ----VYNPCNKCENC 78
Cdd:PRK14954    8 RKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQrmidDPVylqeVTEPCGECESC 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  79 VSINNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNL 158
Cdd:PRK14954   88 RDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTEL 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 159 EKVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKF-----GEMKITH 233
Cdd:PRK14954  168 HKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFsvgseAEKVIAY 247
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 234 QDTLDILGLFDENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYI--FDSLINEKRSNLI 301
Cdd:PRK14954  248 QGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFrnFLVLYNLRSTRLI 317
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
7-301 6.59e-83

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 261.37  E-value: 6.59e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   7 RKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCM----DP----QVYNPCNKCENC 78
Cdd:PRK14955    8 RKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQrmidDAdylqEVTEPCGECESC 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  79 VSINNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNL 158
Cdd:PRK14955   88 RDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTEL 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 159 EKVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKF-----GEMKITH 233
Cdd:PRK14955  168 HKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFsveseGEGSIRY 247
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 234 QDTLDILGLFDENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLI--NEKRSNLI 301
Cdd:PRK14955  248 DKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVvhNLRSTRLV 317
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
5-257 3.17e-82

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 258.20  E-value: 3.17e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14961    6 LARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEKG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14961   86 LCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK14961  166 ILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDMLGLLN 245
                         250
                  ....*....|...
gi 1341788698 245 ENFIVQFIENVSN 257
Cdd:PRK14961  246 EKQSFLLTDALLK 258
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
5-302 3.24e-81

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 259.49  E-value: 3.24e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14956    8 LSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKG 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14956   88 ISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPET 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGL-- 242
Cdd:PRK14956  168 ILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMIGYhg 247
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341788698 243 --FDENFIVQFIENVSNSKIDEFLvqsEDLFNLGKDPEILLEQSIEY------IFDSLINEKRSNLIH 302
Cdd:PRK14956  248 ieFLTSFIKSLIDPDNHSKSLEIL---ESLYQEGQDIYKFLWDSIEFthtlnlIRDSLADRESVNFPK 312
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
2-253 1.31e-80

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 261.92  E-value: 1.31e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   2 NNNLYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSI 81
Cdd:PRK14959    3 HASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  82 NNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKV 161
Cdd:PRK14959   83 TQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKF 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 162 PDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILG 241
Cdd:PRK14959  163 PVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGVLG 242
                         250
                  ....*....|..
gi 1341788698 242 LFDENFIVQFIE 253
Cdd:PRK14959  243 LAGQELFLRLME 254
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
5-282 5.46e-80

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 266.59  E-value: 5.46e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14949    6 LARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCVEIAQG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14949   86 RFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKF--GEMKITHQDTLdiLGL 242
Cdd:PRK14949  166 VLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFggGQVMLTQVQTM--LGS 243
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1341788698 243 FDENFIVQFIENVSNSKIdEFLVQS-EDLFNLGKDPE----ILLE 282
Cdd:PRK14949  244 IDEQHVIALLKALTDADI-GVLMQTcAQVLAFGADAQevlrSLLE 287
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
1-266 2.39e-79

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 260.37  E-value: 2.39e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   1 MNNNLYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVS 80
Cdd:PRK14960    1 MYQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  81 INNNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEK 160
Cdd:PRK14960   81 VNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 161 VPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDIL 240
Cdd:PRK14960  161 LPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEML 240
                         250       260
                  ....*....|....*....|....*....
gi 1341788698 241 GLFDENFIVQFIENV---SNSKIDEFLVQ 266
Cdd:PRK14960  241 GLIDRTIIYDLILAVhqnQREKVSQLLLQ 269
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
5-311 5.50e-79

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 255.39  E-value: 5.50e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14957    6 LARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINNN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14957   86 SFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK14957  166 ILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQMLGIID 245
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341788698 245 ENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSNLIHL----MGIFNNIL 311
Cdd:PRK14957  246 SEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVndidVDIINNIL 316
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
5-253 3.23e-78

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 260.17  E-value: 3.23e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK07003    6 LARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK07003   86 RFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PRK07003  166 VLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGMLGALD 245

                  ....*....
gi 1341788698 245 ENFIVQFIE 253
Cdd:PRK07003  246 QTYMVRLLD 254
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
7-363 4.61e-78

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 252.09  E-value: 4.61e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   7 RKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYN----PCNKCENCVSIN 82
Cdd:PRK06645   13 RKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITENttikTCEQCTNCISFN 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  83 NNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVP 162
Cdd:PRK06645   93 NHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIP 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 163 DTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQV----EKFGEMkITHQDTLD 238
Cdd:PRK06645  173 ATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAasmsAKSDNI-ISPQVINQ 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 239 ILGLFDENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYI-------------------FDSLINE---- 295
Cdd:PRK06645  252 MLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESVSDFIaylnkvkmlpnyslpiyesFNDRTKSildk 331
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 296 -KRSNLIHLMGIFNNILKDLKYSENKRLIFDVEILDFMHkysTTSVPLLHE-NEKTPNRNQVTTESVIKE 363
Cdd:PRK06645  332 iSLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIKSIY---STSLPLLTDfDGNNQNLNQSINPEIKKK 398
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
7-276 3.63e-76

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 242.86  E-value: 3.63e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   7 RKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCmdPQVYNPcnkcencvsiNNNSF 86
Cdd:PRK14970    9 RKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQ--PGYDDP----------NEDFS 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  87 LDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTII 166
Cdd:PRK14970   77 FNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTIL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 167 SRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILGLFDEN 246
Cdd:PRK14970  157 SRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYD 236
                         250       260       270
                  ....*....|....*....|....*....|
gi 1341788698 247 FIVQFIENVSNSKIDEFLVQSEDLFNLGKD 276
Cdd:PRK14970  237 TYINVTDLILENKIPELLLAFNEILRKGFD 266
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
5-290 2.81e-72

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 239.01  E-value: 2.81e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSI--N 82
Cdd:PRK14952    3 LYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALapN 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  83 NNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVP 162
Cdd:PRK14952   83 GPGSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 163 DTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYElDALQIIAKRAKGG-MRDAISMLEQ--VEKFGEmKITHQDTLDI 239
Cdd:PRK14952  163 PTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVD-DAVYPLVIRAGGGsPRDTLSVLDQllAGAADT-HVTYQRALGL 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1341788698 240 LGLFDENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFD 290
Cdd:PRK14952  241 LGATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRD 291
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
5-222 1.10e-71

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 242.20  E-value: 1.10e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSI--N 82
Cdd:PRK07764    5 LYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALapG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  83 NNSFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVP 162
Cdd:PRK07764   85 GPGSLDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVI 164
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341788698 163 DTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYElDALQIIAKRAKGG-MRDAISMLEQ 222
Cdd:PRK07764  165 GTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVE-PGVLPLVIRAGGGsVRDSLSVLDQ 224
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
5-413 3.32e-71

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 234.24  E-value: 3.32e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNN 84
Cdd:PRK14958    6 LARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDVIEMDAASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PRK14958   86 RFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKI------THQDTLD 238
Cdd:PRK14958  166 VLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVliadvkTMLGTIE 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 239 ILGLFDenfIVQFIENVSNSK----IDEFLVQSEDLFNLGKD--------------PEILLEQSIEYI--FDSLINEKRS 298
Cdd:PRK14958  246 PLLLFD---ILEALAAKAGDRllgcVTRLVEQGVDFSNALADllsllhqiaiiqtvPEALIENDSEQLrqLAKLLDREDV 322
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 299 NLIHLMGIFNNilKDLKYSENKRLIFDVEILDFMHKY--STTSVPLLHENEKTpnrnqVTTESVIKETQHPIMKKILdyf 376
Cdd:PRK14958  323 QLFYQIGLIGQ--RDLAYSPTPQTGFEMTLLRMLAFYpsAANAIPETESKEAV-----VTPTPKSSETSWPQLLSQL--- 392
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 1341788698 377 sdpheKKSNMAIYFALLFSNPEIENNKIHFKFSSGQK 413
Cdd:PRK14958  393 -----KLTGATLALAQQCSLKELTDNRLYLMLNPKQK 424
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
20-229 7.76e-56

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 187.10  E-value: 7.76e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  20 QPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCEnCVSINNNSFLDVIEM---DAAS 96
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELnpeEKSD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  97 NRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKN 176
Cdd:COG0470    80 QIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1341788698 177 LGQNEIVEGLKniasSEGmeYELDALQIIAKRAKGGMRDAISMLEQVEKFGEM 229
Cdd:COG0470   160 PSEEEALAWLR----EEG--VDEDALEAILRLAGGDPRAAINLLQALAGRKEL 206
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
25-203 5.47e-55

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 181.67  E-value: 5.47e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  25 KYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDVIEMDAASNR-GIDEI 103
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSiKVDQV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 104 RNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKNLGQNEIV 183
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALL 161
                         170       180
                  ....*....|....*....|
gi 1341788698 184 EGLKNIASSEGMEYELDALQ 203
Cdd:TIGR00678 162 QWLIRQGISEEAAELLLALA 181
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
19-177 1.53e-53

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 177.02  E-value: 1.53e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  19 GQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDV--IEMDAAS 96
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLviIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  97 NRgIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKN 176
Cdd:pfam13177  81 IK-IDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  .
gi 1341788698 177 L 177
Cdd:pfam13177 160 L 160
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
20-186 1.04e-40

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 148.54  E-value: 1.04e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  20 QPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDV--IEMDAASN 97
Cdd:PRK08058   11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVhlVAPDGQSI 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  98 RgIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKNL 177
Cdd:PRK08058   91 K-KDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPL 169

                  ....*....
gi 1341788698 178 GQNEIVEGL 186
Cdd:PRK08058  170 PPESLIQRL 178
rfc PRK00440
replication factor C small subunit; Reviewed
8-220 3.25e-31

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 122.29  E-value: 3.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   8 KYRPLDFDEILGQPHVVKYFKNALNKQEVSHaYIFSGPRGTGKTTTARILAKVLNCMDPQvynpcnkcENcvsinnnsFL 87
Cdd:PRK00440   10 KYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALARELYGEDWR--------EN--------FL 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  88 dviEMDAASNRGIDEIRN-IRDSSNYRPVYG-KYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTI 165
Cdd:PRK00440   73 ---ELNASDERGIDVIRNkIKEFARTAPVGGaPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPI 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1341788698 166 ISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISML 220
Cdd:PRK00440  150 QSRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL 204
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
12-242 7.79e-31

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 121.16  E-value: 7.79e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  12 LDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMdpqvyNPCNKCENCVSINNN--SFLDV 89
Cdd:PRK07399    1 NLFANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLSQ-----GSPSKNIRRRLEEGNhpDLLWV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  90 ----------IEMDAASNRG----------IDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEpPSHV 149
Cdd:PRK07399   76 eptyqhqgklITASEAEEAGlkrkappqirLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNG 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 150 VFILATTNLEKVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQV--EKFG 227
Cdd:PRK07399  155 TLILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPGAAIANIEQLQSIppELLQ 234
                         250
                  ....*....|....*
gi 1341788698 228 EMKITHQDTLDILGL 242
Cdd:PRK07399  235 KLEQPPKSPLEALEL 249
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
8-241 1.20e-28

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 115.47  E-value: 1.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   8 KYRPLDFDEILGQPHVVKYFKNALNKQEVSHaYIFSGPRGTGKTTTARILAKVLncmdpqvYNPCNKcENCVSINNNSFL 87
Cdd:PRK12402    8 KYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALAREL-------YGDPWE-NNFTEFNVADFF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  88 D--------------------VIEMDAASNrgIDEIrnIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPS 147
Cdd:PRK12402   79 DqgkkylvedprfahflgtdkRIRSSKIDN--FKHV--LKEYASYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSR 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 148 HVVFILATTNLEKVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLeQVEKFG 227
Cdd:PRK12402  155 TCRFIIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTL-QTAALA 233
                         250
                  ....*....|....
gi 1341788698 228 EMKITHQDTLDILG 241
Cdd:PRK12402  234 AGEITMEAAYEALG 247
PRK04195 PRK04195
replication factor C large subunit; Provisional
8-221 1.69e-23

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 102.69  E-value: 1.69e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   8 KYRPLDFDEILGQPHVVKYFKNALN---KQEVSHAYIFSGPRGTGKTTTARILAKVLNcmdpqvynpcnkcencvsinnn 84
Cdd:PRK04195    7 KYRPKTLSDVVGNEKAKEQLREWIEswlKGKPKKALLLYGPPGVGKTSLAHALANDYG---------------------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 sfLDVIEMDAASNRGIDEIRNI-RDSSNYRPVYG-KYKVYIIDEFHMLT----REAFNALLKTLEEPPSHVVFIlATTNL 158
Cdd:PRK04195   65 --WEVIELNASDQRTADVIERVaGEAATSGSLFGaRRKLILLDEVDGIHgnedRGGARAILELIKKAKQPIILT-ANDPY 141
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341788698 159 EKVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLE 221
Cdd:PRK04195  142 DPSLRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQ 204
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
14-173 2.27e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 101.53  E-value: 2.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  14 FDEILGQPHVVKYFKNA---------LNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVyNPCNKCENCVSINNN 84
Cdd:PRK07940    4 WDDLVGQEAVVAELRAAaraaradvaAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQCTDPDE-PGCGECRACRTVLAG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 SFLDV--IEMDAASnRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVP 162
Cdd:PRK07940   83 THPDVrvVAPEGLS-IGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVL 161
                         170
                  ....*....|.
gi 1341788698 163 DTIISRSQIIN 173
Cdd:PRK07940  162 PTIRSRCRHVA 172
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
8-241 3.47e-23

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 101.31  E-value: 3.47e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   8 KYRPLDFDEILGQPHVV---KYFKNALNKQEVSHAyIFSGPRGTGKTTTARILAKVLNcmdpqvynpcnkcencvsinnn 84
Cdd:PRK13342    5 RMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGATD---------------------- 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 sfLDVIEMDAASNrGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHmltReaFN-----ALLKTLEEppSHVVFILATTnlE 159
Cdd:PRK13342   62 --APFEALSAVTS-GVKDLREVIEEARQRRSAGRRTILFIDEIH---R--FNkaqqdALLPHVED--GTITLIGATT--E 129
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 160 ----KVPDTIISRSQIINFKNLGQNEIVEGLKN-IASSEGMEYEL--DALQIIAKRAKGGMRDAISMLEQVEKFGEmKIT 232
Cdd:PRK13342  130 npsfEVNPALLSRAQVFELKPLSEEDIEQLLKRaLEDKERGLVELddEALDALARLANGDARRALNLLELAALGVD-SIT 208

                  ....*....
gi 1341788698 233 HQDTLDILG 241
Cdd:PRK13342  209 LELLEEALQ 217
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
12-293 5.84e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 95.87  E-value: 5.84e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  12 LDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILA-KVLNcmdpqvynpcnkcencvSINNNSFLDVI 90
Cdd:PRK05564    1 MSFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIAlKILG-----------------KSQQREYVDII 63
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  91 EMDAASNR--GIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISR 168
Cdd:PRK05564   64 EFKPINKKsiGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSR 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 169 SQIINFKNLGQNEI---VEGLKNIASSEGMEYELDALQIIAKRAKGGMRDaismleqvEKFGEMKithqdtldilglfde 245
Cdd:PRK05564  144 CQIYKLNRLSKEEIekfISYKYNDIKEEEKKSAIAFSDGIPGKVEKFIED--------DSLKNIR--------------- 200
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1341788698 246 NFIVQFIENVSNSKIDEFLVQSEDLFNLGKDPEILLEQSIEYIFDSLI 293
Cdd:PRK05564  201 NMSLEILKDIKKSNINILLKYENFLIKYKENWEEILTCILSYIRDSLL 248
PLN03025 PLN03025
replication factor C subunit; Provisional
8-277 2.84e-20

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 91.33  E-value: 2.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   8 KYRPLDFDEILGQPHVVKYFKnALNKQEVSHAYIFSGPRGTGKTTTARILAKVLncmdpqvynpcnkcencvsINNNSFL 87
Cdd:PLN03025    6 KYRPTKLDDIVGNEDAVSRLQ-VIARDGNMPNLILSGPPGTGKTTSILALAHEL-------------------LGPNYKE 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  88 DVIEMDAASNRGIDEIRNIRDSSNYRPVY---GKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDT 164
Cdd:PLN03025   66 AVLELNASDDRGIDVVRNKIKMFAQKKVTlppGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEP 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 165 IISRSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLeQVEKFGEMKITHQDTLDILGLFD 244
Cdd:PLN03025  146 IQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNL-QATHSGFGFVNQENVFKVCDQPH 224
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1341788698 245 ENFIVQFIENVSNSKIDEFLVQSEDLFNLGKDP 277
Cdd:PLN03025  225 PLHVKNIVRNCLKGKFDDACDGLKQLYDLGYSP 257
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
20-176 3.06e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 90.46  E-value: 3.06e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  20 QPHVVKYFKNALNKQEVSHAYIFSGprGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDV--IEmdaASN 97
Cdd:PRK07276    7 QPKVFQRFQTILEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVtvIE---PQG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  98 RGI--DEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINF- 174
Cdd:PRK07276   82 QVIktDTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFp 161

                  ..
gi 1341788698 175 KN 176
Cdd:PRK07276  162 KN 163
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
38-202 3.27e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 91.30  E-value: 3.27e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  38 HAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLD--VIEMDAAS-NRGIDEIRNIRDSSNYRP 114
Cdd:PRK05707   23 HAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDnfVLEPEEADkTIKVDQVRELVSFVVQTA 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 115 VYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKNLGQNEIVEGLKNiASSEG 194
Cdd:PRK05707  103 QLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWLQQ-ALPES 181

                  ....*...
gi 1341788698 195 MEYELDAL 202
Cdd:PRK05707  182 DERERIEL 189
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
179-241 8.56e-19

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 80.24  E-value: 8.56e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341788698 179 QNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLDILG 241
Cdd:cd18137     3 VEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
39-168 1.44e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 86.46  E-value: 1.44e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  39 AYIFSGPRGTGKTTTARILAKVLNCMDPQVYN-PCNKCENCVSINNNSFLDVIEMDAASNR----------GIDEIRNIR 107
Cdd:PRK08699   23 AWLFAGKKGIGKTAFARFAAQALLCETPAPGHkPCGECMSCHLFGQGSHPDFYEITPLSDEpengrkllqiKIDAVREII 102
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341788698 108 DSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISR 168
Cdd:PRK08699  103 DNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSR 163
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
38-253 2.30e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 85.94  E-value: 2.30e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  38 HAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDVIEMDAASNR--GIDEIRNIRDSSNYRPV 115
Cdd:PRK06871   25 HALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPIDNKdiGVDQVREINEKVSQHAQ 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 116 YGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKNLGQNEIVEGLKNIASSEGM 195
Cdd:PRK06871  105 QGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWLIHPPEEQQALDWLQAQSSAEIS 184
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341788698 196 EYELdALQIIAKRAkggmRDAISMLEQ--VEKFGEMKIT------HQDTLDILGLFDENFIVQFIE 253
Cdd:PRK06871  185 EILT-ALRINYGRP----LLALTFLEQglLEQRKTFLRQfwlfyrRRSPLELLPLFDKELVLQQLD 245
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
38-297 1.63e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 83.55  E-value: 1.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  38 HAYIFSGPRGTGKTTTARILA-KVLNCMDPQvynpcNKCENCVSINNNSFL-------------------DVIEMDAASN 97
Cdd:PRK09112   46 HALLFEGPEGIGKATLAFHLAnHILSHPDPA-----EAPETLADPDPASPVwrqiaqgahpnllhitrpfDEKTGKFKTA 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  98 RGIDEIRNI-----RDSSNyrpvyGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQII 172
Cdd:PRK09112  121 ITVDEIRRVghflsQTSGD-----GNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPI 195
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 173 NFKNLGQNEIVEGLKNIASSEGMEYEldALQIIAKRAKGGMRDAIsmleqvekfgemKITHQDTLDILGLFDENFIVQfi 252
Cdd:PRK09112  196 SLKPLDDDELKKALSHLGSSQGSDGE--ITEALLQRSKGSVRKAL------------LLLNYGGLEIIATIDQLLAGS-- 259
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1341788698 253 enVSNSKIDEFLVQSedlFNlGKDPEILLEQSIEYIFDSLINEKR 297
Cdd:PRK09112  260 --GPDARKAHKLADA---LS-GRESEVQFDFFRDHLLDRIMAEAR 298
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
10-244 2.00e-17

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 84.34  E-value: 2.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  10 RPLDFDEILGQPHVV---KYFKNALNKQEVsHAYIFSGPRGTGKTTTARILAKVLNCmdpqvynpcnkceNCVSINnnsf 86
Cdd:COG2256    20 RPRTLDEVVGQEHLLgpgKPLRRAIEAGRL-SSMILWGPPGTGKTTLARLIANATDA-------------EFVALS---- 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  87 ldviemdaASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHmltReaFN-----ALLKTLEEppSHVVFILATTnlE-- 159
Cdd:COG2256    82 --------AVTSGVKDIREVIEEARERRAYGRRTILFVDEIH---R--FNkaqqdALLPHVED--GTITLIGATT--Enp 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 160 --KVPDTIISRSQIINFKNLGQNEIVEGLKN-IASSE------GMEYELDALQIIAKRAKGGMRDAISMLEQV----EKF 226
Cdd:COG2256   145 sfEVNSALLSRCRVFVLKPLSEEDLEQLLERaLADDErglggyKLELDDEALEALARLADGDARRALNALELAvlsaPPD 224
                         250       260
                  ....*....|....*....|..
gi 1341788698 227 GEMKITHQDTLDILG----LFD 244
Cdd:COG2256   225 GVIEITLELVEEALQrralRYD 246
44 PHA02544
clamp loader, small subunit; Provisional
5-328 1.96e-15

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 76.95  E-value: 1.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   5 LYRKYRPLDFDEILGQPHVVKYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCmdpqvynpcnkcencvsinnn 84
Cdd:PHA02544   11 WEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKALCNEVGA--------------------- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  85 sflDVIEMDAASNRgIDEIRN-IRDSSNYRPVYGKYKVYIIDEFHML-TREAFNALLKTLEEPPSHVVFILATTNLEKVP 162
Cdd:PHA02544   70 ---EVLFVNGSDCR-IDFVRNrLTRFASTVSLTGGGKVIIIDEFDRLgLADAQRHLRSFMEAYSKNCSFIITANNKNGII 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 163 DTIISRSQIINFKNLGQNEIVEGLKN-------IASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMkithqD 235
Cdd:PHA02544  146 EPLRSRCRVIDFGVPTKEEQIEMMKQmivrckgILEAEGVEVDMKVLAALVKKNFPDFRRTINELQRYASTGKI-----D 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 236 TlDILGLFDENFIVQFIENVSNSKIDEF--LVQsedlfNLGKDPEILLEQSIEYIFDSLINEKRSNLIHLMGifnnilkd 313
Cdd:PHA02544  221 A-GILSEVTNSDIDDVVEALKAKDFKAVraLAP-----NYANDYASFVGKLYDELYPQVTPPSIIRLIEIIG-------- 286
                         330
                  ....*....|....*
gi 1341788698 314 lKYSENKRLIFDVEI 328
Cdd:PHA02544  287 -ENNQYHGFAADQEI 300
PRK04132 PRK04132
replication factor C small subunit; Provisional
90-221 7.48e-15

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 77.19  E-value: 7.48e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  90 IEMDAASNRGIDEIRN-IRDSSNYRPVYG-KYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIIS 167
Cdd:PRK04132  600 LELNASDERGINVIREkVKEFARTKPIGGaSFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQS 679
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1341788698 168 RSQIINFKNLGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLE 221
Cdd:PRK04132  680 RCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQ 733
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
38-168 1.44e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 74.80  E-value: 1.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  38 HAYIFSGPRGTGKTTTARILAKVLNCMDPQVY-NPCNKCENCVSINNNSFLD-------VIEMDAASNRG---------- 99
Cdd:PRK06964   22 HALLLHGQAGIGKLDFAQHLAQGLLCETPQPDgEPCGTCAACNWFAQGNHPDyrivrpeALAAEAPGAADeakeadadeg 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 100 ------------IDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIIS 167
Cdd:PRK06964  102 gkktkapskeikIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPTILS 181

                  .
gi 1341788698 168 R 168
Cdd:PRK06964  182 R 182
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
14-211 4.08e-14

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 71.84  E-value: 4.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  14 FDEILGQP-------HVVKYFKNALN----KQEVSHAYIFSGPRGTGKTTTARILAKVLNCmdPQVYnpcNKCENCVSin 82
Cdd:COG1223     1 LDDVVGQEeakkklkLIIKELRRRENlrkfGLWPPRKILFYGPPGTGKTMLAEALAGELKL--PLLT---VRLDSLIG-- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  83 nnSFLDviemDAASNrgideIRNIRDSSNYRPVygkykVYIIDEFHML------------TREAFNALLKTLEEPPSHVV 150
Cdd:COG1223    74 --SYLG----ETARN-----LRKLFDFARRAPC-----VIFFDEFDAIakdrgdqndvgeVKRVVNALLQELDGLPSGSV 137
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341788698 151 FIlATTNLEKVPDTIISR--SQIINFKNLGQNEIVEGLKNIASSEGMEYELDaLQIIAKRAKG 211
Cdd:COG1223   138 VI-AATNHPELLDSALWRrfDEVIEFPLPDKEERKEILELNLKKFPLPFELD-LKKLAKKLEG 198
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
25-338 1.37e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 71.29  E-value: 1.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  25 KYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVsinnnsFLDVIEMDAASNRGIDEIR 104
Cdd:PRK07132    6 KFLDNSATQNKISHSFLLKSNYNEDIDEKILYFLNKFNNLQITNLNEQELPANII------LFDIFDKDLSKSEFLSAIN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 105 NIRDSSNyrpVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFKNLGQNEIVE 184
Cdd:PRK07132   80 KLYFSSF---VQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILA 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 185 GLKNiassegMEYELDALQIIAKRAKGgmrdaismLEQVEKFgemkithqdtldiLGLFDENFIVQFIENVSNSKIDEFL 264
Cdd:PRK07132  157 KLLS------KNKEKEYNWFYAYIFSN--------FEQAEKY-------------INKESENLLKKFEEALNKSLKEKYE 209
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341788698 265 VQSEDLFNLGKDPEILLEQSIEYIFDSLINEKRSnlihlmgIFNNILKDLKYSENKRLIFDVEILDFMHKYSTT 338
Cdd:PRK07132  210 LILFLNKKLTKENALFLLKLLKFFFKSIFANKKK-------KNPKNIKVAFSKKKKFKIEFFELITIIDEFLNS 276
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
41-235 1.85e-13

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 71.87  E-value: 1.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  41 IFSGPRGTGKTTTARILAKVLNcmdpqvynpcnkcencvsinnnsfLDVIEMDAA---------SNRGIDEIrnIRDSSN 111
Cdd:COG0464   195 LLYGPPGTGKTLLARALAGELG------------------------LPLIEVDLSdlvskyvgeTEKNLREV--FDKARG 248
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 112 YRPVygkykVYIIDEFHML-----------TREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISR-SQIINFKNLGQ 179
Cdd:COG0464   249 LAPC-----VLFIDEADALagkrgevgdgvGRRVVNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRfDEIIFFPLPDA 323
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341788698 180 NEIVEGLKNIASSEGMEYELDaLQIIAKRAKGG----MRDAI-SMLEQVEKFGEMKITHQD 235
Cdd:COG0464   324 EERLEIFRIHLRKRPLDEDVD-LEELAEATEGLsgadIRNVVrRAALQALRLGREPVTTED 383
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
100-169 5.46e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 69.44  E-value: 5.46e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 100 IDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRS 169
Cdd:PRK05917   77 IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRS 146
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
30-175 3.55e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 64.21  E-value: 3.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  30 ALNKQEVSHAYIFSGPRGTGKTTTARILAK-VL-NCMDPQVYNPCNKCencvsINNNSFLDVIEMDAASNRGIDEIR--- 104
Cdd:PRK08769   19 ALDAGRLGHGLLICGPEGLGKRAVALALAEhVLaSGPDPAAAQRTRQL-----IAAGTHPDLQLVSFIPNRTGDKLRtei 93
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341788698 105 ---NIRDSSN---YRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFK 175
Cdd:PRK08769   94 vieQVREISQklaLTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFK 170
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-172 4.06e-11

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 61.01  E-value: 4.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  19 GQPHVVKYFKNALNKQEVSHaYIFSGPRGTGKTTTARILAKVLncmdpqvynpcnkcencvsinNNSFLDVIEMDAASNR 98
Cdd:cd00009     2 GQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANEL---------------------FRPGAPFLYLNASDLL 59
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  99 GIDEIRNIRDSSNYR-----PVYGKYKVYIIDEFHMLTREAFNALLKTLEE------PPSHVVFILATTNLE--KVPDTI 165
Cdd:cd00009    60 EGLVVAELFGHFLVRllfelAEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNRPLlgDLDRAL 139

                  ....*..
gi 1341788698 166 ISRSQII 172
Cdd:cd00009   140 YDRLDIR 146
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
40-177 1.41e-10

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 58.76  E-value: 1.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  40 YIFSGPRGTGKTTTARILAKVLNCmdpqvynpcnkceNCVSINNNSFLDVIEMDAASNrgideIRNI-RDSSNYRPvygk 118
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGA-------------PFIEISGSELVSKYVGESEKR-----LRELfEAAKKLAP---- 58
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341788698 119 yKVYIIDEFHML-----------TREAFNALLKTLEEP---PSHVVFILATTNLEKVPDTIISRSQIINFKNL 177
Cdd:pfam00004  59 -CVIFIDEIDALagsrgsggdseSRRVVNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
28-170 2.26e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 61.74  E-value: 2.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  28 KNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLNCMDPQVyNPCNKCENCVSINNNSFLD--VIEMDAASNR-GIDEIR 104
Cdd:PRK06090   16 KAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQS-EACGFCHSCELMQSGNHPDlhVIKPEKEGKSiTVEQIR 94
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341788698 105 NIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQ 170
Cdd:PRK06090   95 QCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQ 160
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
38-168 3.82e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 61.23  E-value: 3.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  38 HAYIFSGPRGTGKTTTARILAKVLNCMDPQVYNPCNKCENCVSINNNSFLDVIEMD---AASNRGIDEIRNIRDSSNYRP 114
Cdd:PRK07993   25 HALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLTpekGKSSLGVDAVREVTEKLYEHA 104
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1341788698 115 VYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISR 168
Cdd:PRK07993  105 RLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSR 158
PRK13341 PRK13341
AAA family ATPase;
10-224 1.11e-09

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 60.84  E-value: 1.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  10 RPLDFDEILGQPHVV---KYFKNALNKQEVSHAyIFSGPRGTGKTTTARILAKVLNCmdpqvynpcnkceNCVSINnnsf 86
Cdd:PRK13341   23 RPRTLEEFVGQDHILgegRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANHTRA-------------HFSSLN---- 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  87 ldviemdaASNRGIDEIRNIRDSSNYR-PVYGKYKVYIIDEFHMLTREAFNALLKTLEEppSHVVFILATTnlE----KV 161
Cdd:PRK13341   85 --------AVLAGVKDLRAEVDRAKERlERHGKRTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATT--EnpyfEV 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 162 PDTIISRSQIINFKNLGQN---EIVE-GLKNIASSEG---MEYELDALQIIAKRAKGgmrDAISMLEQVE 224
Cdd:PRK13341  153 NKALVSRSRLFRLKSLSDEdlhQLLKrALQDKERGYGdrkVDLEPEAEKHLVDVANG---DARSLLNALE 219
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
71-168 1.95e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 55.22  E-value: 1.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  71 PCNKCENCVSINNNSFLDVIEM-DAASNRGIDEIRNIRDSSNYRPV--YGKyKVYIIDEFHMLTREAFNALLKTLEEPPS 147
Cdd:PRK05818   39 FCKTCESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINKLNRPSVesNGK-KIYIIYGIEKLNKQSANSLLKLIEEPPK 117
                          90       100
                  ....*....|....*....|.
gi 1341788698 148 HVVFILATTNLEKVPDTIISR 168
Cdd:PRK05818  118 NTYGIFTTRNENNILNTILSR 138
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
40-169 2.15e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.15  E-value: 2.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698   40 YIFSGPRGTGKTTTARILAKVLNCMDPQV-YNPCNKCENCVSINNNsfLDVIEMDAASNRGIDEIRNIRDssnyRPVYGK 118
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGViYIDGEDILEEVLDQLL--LIIVGGKKASGSGELRLRLALA----LARKLK 78
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1341788698  119 YKVYIIDEFHMLTREAFNALLKTLEEPPSHV-------VFILATTNLEKVPDTIISRS 169
Cdd:smart00382  79 PDVLILDEITSLLDAEQEALLLLLEELRLLLllkseknLTVILTTNDEKDLGPALLRR 136
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
177-221 1.55e-07

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 48.29  E-value: 1.55e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1341788698 177 LGQNEIVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLE 221
Cdd:cd18140     1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQ 45
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
38-240 1.31e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 50.41  E-value: 1.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  38 HAYIFSGPRGTGKTTTA-RI----LAKVLNCMDPQVYNPCNkcencvsinnnsfLDVIEMDAASNR-------------- 98
Cdd:PRK07471   42 HAWLIGGPQGIGKATLAyRMarflLATPPPGGDGAVPPPTS-------------LAIDPDHPVARRiaagahgglltler 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  99 -------------GIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTI 165
Cdd:PRK07471  109 swnekgkrlrtviTVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTI 188
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341788698 166 ISRSQIINFKNLGqneiVEGLKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLeqveKFGEMKItHQDTLDIL 240
Cdd:PRK07471  189 RSRCRKLRLRPLA----PEDVIDALAAAGPDLPDDPRAALAALAEGSVGRALRLA----GGDGLAL-YRRLTALL 254
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
117-281 1.94e-06

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 49.48  E-value: 1.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 117 GKYKVYIIDEFHMLTR--EAFNALLKTLEEPPSHVVFILATTNLE---KVPDTIISRSQIINFKNLGQNEIVEGLKNIAS 191
Cdd:COG1466    61 GERRLVIVRNAEFLKKpgEGLEALEAYLANPPPDTVLVLTAGKLDkrkKLFKALEKAGVVVECYPLKERELPAWIRQRLK 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 192 SEGMEYELDALQIIAKRAKGGMRDAISMLEQVE--KFGEMKITHQDTLDILGLFDENFIVQFIENVSNSKIDEFLVQSED 269
Cdd:COG1466   141 AAGLRIDPDAAQLLAERVGGDLLALAQELEKLAlyAGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRR 220
                         170
                  ....*....|..
gi 1341788698 270 LFNLGKDPEILL 281
Cdd:COG1466   221 LLAEGEEPVLIL 232
AAA_22 pfam13401
AAA domain;
41-161 2.86e-06

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 46.57  E-value: 2.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  41 IFSGPRGTGKTTTARILAKVLNCMDPQVY-----NPCNKCENCVSINNNsfldvIEMDAASNRGIDEIRN-IRDSSNyrp 114
Cdd:pfam13401   9 VLTGESGTGKTTLLRRLLEQLPEVRDSVVfvdlpSGTSPKDLLRALLRA-----LGLPLSGRLSKEELLAaLQQLLL--- 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1341788698 115 VYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILA-TTNLEKV 161
Cdd:pfam13401  81 ALAVAVVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILVgTPELREL 128
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
121-175 1.95e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 45.41  E-value: 1.95e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1341788698 121 VYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINFK 175
Cdd:PRK08485   57 KIIVIAAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRK 111
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
10-62 3.68e-05

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 44.03  E-value: 3.68e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1341788698  10 RPLDFDEILGQPHVVK----YFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKVLN 62
Cdd:pfam05496   2 RPRTLDEYIGQEKVKEnlkiFIEAAKQRGEALDHVLLYGPPGLGKTTLANIIANEMG 58
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
95-197 6.91e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 44.45  E-value: 6.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  95 ASNRGIDEIRNIRDSSNYRPVYGKYKVYIIDEFHMLTREAFNALLKTLEEPPSHVVFILATTNLEKVPDTIISRSQIINF 174
Cdd:PRK06581   66 AKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRCFKINV 145
                          90       100
                  ....*....|....*....|....*..
gi 1341788698 175 KNL---GQNEI-VEGLKNIASSEGMEY 197
Cdd:PRK06581  146 RSSilhAYNELySQFIQPIADNKTLDF 172
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
10-62 1.29e-04

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 43.97  E-value: 1.29e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1341788698  10 RPLDFDEILGQPHVVK----YFKNALNKQEV-SHAyIFSGPRGTGKTTTARILAKVLN 62
Cdd:PRK00080   20 RPKSLDEFIGQEKVKEnlkiFIEAAKKRGEAlDHV-LLYGPPGLGKTTLANIIANEMG 76
PRK04132 PRK04132
replication factor C small subunit; Provisional
8-53 1.54e-04

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 44.44  E-value: 1.54e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1341788698   8 KYRPLDFDEILGQPHVVKYFKNALNKQEVSHaYIFSGPRGTGKTTT 53
Cdd:PRK04132   12 KYRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGKCLT 56
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
186-238 1.12e-03

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 37.45  E-value: 1.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1341788698 186 LKNIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKFGEMKITHQDTLD 238
Cdd:cd18133    10 LAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDDGKISLDRVY 62
ChlI COG1239
Mg-chelatase subunit ChlI [Coenzyme transport and metabolism];
44-78 2.25e-03

Mg-chelatase subunit ChlI [Coenzyme transport and metabolism];


Pssm-ID: 440852 [Multi-domain]  Cd Length: 344  Bit Score: 40.12  E-value: 2.25e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1341788698  44 GPRGTGKTTTARILAKVL-----------NCmDPQvyNPCNKCENC 78
Cdd:COG1239    37 GEKGTAKSTAVRALAALLppievvkgcpyNC-DPD--DPDELCPDC 79
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
25-138 2.99e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 39.93  E-value: 2.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698  25 KYFKNALNKQEVSHAYIFSGPRGTGKTTTARILAKvlncmdpqvynpcnKCENCVSINnnsfLDVIEMDAASNRGIDEIR 104
Cdd:COG1373     8 KILDKLLKLLDNRKAVVITGPRQVGKTTLLKQLAK--------------ELENILYIN----LDDPRLRALAEEDPDDLL 69
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1341788698 105 nirdsSNYRPVYGKYKVYIIDEFHMLtREAFNAL 138
Cdd:COG1373    70 -----EALKELYPGKTYLFLDEIQRV-PEWEDAL 97
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
44-63 4.73e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 37.54  E-value: 4.73e-03
                          10        20
                  ....*....|....*....|
gi 1341788698  44 GPRGTGKTTTARILAKVLNC 63
Cdd:cd00464     6 GMMGAGKTTVGRLLAKALGL 25
holA TIGR01128
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ...
114-281 6.43e-03

DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273455 [Multi-domain]  Cd Length: 302  Bit Score: 38.39  E-value: 6.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 114 PVYGKYKVYIIDEFHMLT-REAFNALLKTLEEPPSHVVFILATTNLEK-----VPDTIISRSQIINFKNLGQNEIVEGLK 187
Cdd:TIGR01128  42 PLFSERRLVELRNPEGKPgAKGLKALEEYLANPPPDTLLLIEAPKLDKrkkltKWLKALKNAEIVECKTPKEQELPRWIQ 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 188 NIASSEGMEYELDALQIIAKRAKGGMRDAISMLEQVEKF-GEMKITHQDTLDILGLFDENFIVQFIENVSNSKIDEFLVQ 266
Cdd:TIGR01128 122 ARLKKLGLRIDPDAVQLLAELVEGNLLAIAQELEKLALYaPDGKITLEDVEEAVSDSARFNVFDLTDALLEGKAARALRI 201
                         170
                  ....*....|....*
gi 1341788698 267 SEDLFNLGKDPEILL 281
Cdd:TIGR01128 202 LKGLLGEGEEPLILL 216
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
121-253 6.71e-03

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 38.80  E-value: 6.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341788698 121 VYIIDEFHMLTREAFNALLKTLEEPPSHVVfILAT---------TNLEK---VPDTIISRSQIINFKNLGQNEIVEGLKN 188
Cdd:COG1224   295 VLFIDDAHMLDIEAFSFLTRAMESELAPII-ILATnrgitkirgTDIESphgIPLDLLDRLLIIPTRPYTEDEIREIIKI 373
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341788698 189 IASSEGMEYELDALQIIAK-RAKGGMRDAISMLE--QV--EKFGEMKITHQDTLDILGLF-DENFIVQFIE 253
Cdd:COG1224   374 RAEEEDIELSDDALEELTKiGVERSLRYAVQLLEpaYIiaKRRGRSKVTVEDVEEASKLFaDVKESVEYVK 444
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
41-63 7.87e-03

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 37.03  E-value: 7.87e-03
                          10        20
                  ....*....|....*....|...
gi 1341788698  41 IFSGPRGTGKTTTARILAKVLNC 63
Cdd:COG0703     2 VLIGMMGAGKSTVGRLLAKRLGL 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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