|
Name |
Accession |
Description |
Interval |
E-value |
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-251 |
2.97e-118 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 338.17 E-value: 2.97e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:COG0411 4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIARLGIAR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLIHKYNDSLFSVFSKSKMNF--DKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEM 158
Cdd:COG0411 84 TFQNPRLFPELTVLENVLVAAHARLGRGLLAALLRLPRARreEREARERAEELLERVGLADRADEPAGNLSYGQQRRLEI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:COG0411 164 ARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDeRGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVRAD 243
|
250
....*....|....
gi 1341787947 238 EEVVKVYLGEDENA 251
Cdd:COG0411 244 PRVIEAYLGEEAAA 257
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
2-240 |
1.11e-104 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 302.82 E-value: 1.11e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLGIGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLIHKYNDSLFSVFSKSKMnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:cd03219 81 FQIPRLFPELTVLENVMVAAQARTGSGLLLARARREE---REARERAEELLERVGLADLADRPAGELSYGQQRRLEIARA 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEV 240
Cdd:cd03219 158 LATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPRV 236
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1-248 |
1.48e-79 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 239.89 E-value: 1.48e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:PRK11300 5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMGVVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLIHKYNDSLFSVFSKSKmNFDKEAREKV------LEVAEMFDIKNRLTsypSQLTYGMLK 154
Cdd:PRK11300 85 TFQHVRLFREMTVIENLLVAQHQQLKTGLFSGLLKTP-AFRRAESEALdraatwLERVGLLEHANRQA---GNLAYGQQR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:PRK11300 161 RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIaELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEE 240
|
250
....*....|....*
gi 1341787947 234 IANNEEVVKVYLGED 248
Cdd:PRK11300 241 IRNNPDVIKAYLGEA 255
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-247 |
4.21e-71 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 218.06 E-value: 4.21e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:COG4674 10 ILYVEDLTVSFDGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDEHEIARLGIGR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLihKYNDSLFSV-FSKskmnFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMA 159
Cdd:COG4674 90 KFQKPTVFEELTVFENLELAL--KGDRGVFASlFAR----LTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEE----IKSIiqmvnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:COG4674 164 MLLAQDPKLLLLDEPVAGMTDAETERtaelLKSL-----AGKHSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGSLDEVQ 238
|
250
....*....|..
gi 1341787947 236 NNEEVVKVYLGE 247
Cdd:COG4674 239 ADPRVIEVYLGR 250
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-246 |
2.15e-57 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 182.49 E-value: 2.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:COG0410 3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLGIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLIHKyndslfsvfskskmnFDKEAREKVLE-VAEMF-DIKNRLTSYPSQLTYG---MLkr 155
Cdd:COG0410 83 VPEGRRIFPSLTVEENLLLGAYAR---------------RDRAEVRADLErVYELFpRLKERRRQRAGTLSGGeqqML-- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 vEMARAVISDPDLLLLDEPAAGL--NYyeTEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:COG0410 146 -AIGRALMSRPKLLLLDEPSLGLapLI--VEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAE 222
|
250
....*....|...
gi 1341787947 234 IANNEEVVKVYLG 246
Cdd:COG0410 223 LLADPEVREAYLG 235
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-249 |
4.37e-56 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 179.10 E-value: 4.37e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTH---DIIYMgi 78
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEvrrRIGYV-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 srtFQNLQLFQAMNVFENI-YSGLIHKYNdslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:COG1131 79 ---PQEPALYPDLTVRENLrFFARLYGLP--------------RKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLG 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:COG1131 142 LALALLHDPELLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKAR 221
|
250
....*....|....
gi 1341787947 238 --EEVVKVYLGEDE 249
Cdd:COG1131 222 llEDVFLELTGEEA 235
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-237 |
8.91e-55 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 175.32 E-value: 8.91e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAGIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLIHKYNDSlfsvfskskmnfDKEAREKVLevaEMFDI-KNRLTSYPSQLTYG---MLkrvE 157
Cdd:cd03224 81 PEGRRIFPELTVEENLLLGAYARRRAK------------RKARLERVY---ELFPRlKERRKQLAGTLSGGeqqML---A 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:cd03224 143 IARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLAD 222
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-224 |
1.95e-54 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 174.24 E-value: 1.95e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRT 81
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPER---RNIGMV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:cd03259 78 FQDYALFPHLTVAENIAFGL-------------KLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKS-IIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03259 145 LAREPSLLLLDEPLSALDAKLREELREeLKELQRELGITTIYVTHDQEEALALADRIAVMNEGR 208
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-244 |
2.07e-54 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 175.28 E-value: 2.07e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESlLKLDTHDIIYM---- 76
Cdd:COG1121 6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKP-PRRARRRIGYVpqra 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQnlqlfqaMNVFENIYSGLIHKynDSLFSVFSKSkmnfDKEAREKVLEVAEMFDIKNRLTsypSQLTYGMLKRV 156
Cdd:COG1121 85 EVDWDFP-------ITVRDVVLMGRYGR--RGLFRRPSRA----DREAVDEALERVGLEDLADRPI---GELSGGQQQRV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNfGKKIAEGTPEDIAN 236
Cdd:COG1121 149 LLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLN-RGLVAHGPPEEVLT 227
|
....*...
gi 1341787947 237 NEEVVKVY 244
Cdd:COG1121 228 PENLSRAY 235
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-242 |
2.54e-54 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 174.44 E-value: 2.54e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiymgisR 80
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLREL------R 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 T-----FQN--LQLFqAMNVFENIYSGLihkyndslfsvfskskMNF---DKEAREKVLEVAEMFDIKNRLTSYPSQLTY 150
Cdd:COG1122 75 RkvglvFQNpdDQLF-APTVEEDVAFGP----------------ENLglpREEIRERVEEALELVGLEHLADRPPHELSG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGT 230
Cdd:COG1122 138 GQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217
|
250
....*....|..
gi 1341787947 231 PEDIANNEEVVK 242
Cdd:COG1122 218 PREVFSDYELLE 229
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-245 |
4.09e-54 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 174.40 E-value: 4.09e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDII----YM 76
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYelrrRI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISrtFQNLQLFQAMNVFENIysglihkyndsLFSVFSKSKMNfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRV 156
Cdd:COG1127 85 GML--FQGGALFDSLTVFENV-----------AFPLREHTDLS-EAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKS-IIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:COG1127 151 ALARALALDPEILLYDEPTAGLDPITSAVIDElIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELL 230
|
250
....*....|.
gi 1341787947 236 NNE-EVVKVYL 245
Cdd:COG1127 231 ASDdPWVRQFL 241
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-236 |
7.35e-53 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 171.15 E-value: 7.35e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIY----MG 77
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRlrrrMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 IsrTFQNLQLFQAMNVFENIysglihkyndsLFSVFSKSKMNfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:cd03261 81 M--LFQSGALFDSLTVFENV-----------AFPLREHTRLS-EEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIAN 236
Cdd:cd03261 147 LARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-238 |
1.64e-50 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 165.42 E-value: 1.64e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTH---DIIYMG 77
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREarrQIGVLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 isrtfQNLQLFQAMNVFENI-YSGLIHKyndslfsvfskskmNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRV 156
Cdd:COG4555 81 -----DERGLYDRLTVRENIrYFAELYG--------------LFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIAN 236
Cdd:COG4555 142 ALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELRE 221
|
..
gi 1341787947 237 NE 238
Cdd:COG4555 222 EI 223
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-246 |
5.82e-50 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 163.48 E-value: 5.82e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLGIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGL-IHKYNdslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:cd03218 81 PQEASIFRKLTVEENILAVLeIRGLS--------------KKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIAR 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEV 240
Cdd:cd03218 147 ALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELV 226
|
....*.
gi 1341787947 241 VKVYLG 246
Cdd:cd03218 227 RKVYLG 232
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-248 |
7.77e-50 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 163.28 E-value: 7.77e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLlkldTHDIIY----M 76
Cdd:COG1137 3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI----THLPMHkrarL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQNLQLFQAMNVFENIYSGLihkyndslfSVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRV 156
Cdd:COG1137 79 GIGYLPQEASIFRKLTVEDNILAVL---------ELRKLSK----KEREERLEELLEEFGITHLRKSKAYSLSGGERRRV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHdmNV--VMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG1137 146 EIARALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDH--NVreTLGICDRAYIISEGKVLAEGTPEEI 223
|
250
....*....|....
gi 1341787947 235 ANNEEVVKVYLGED 248
Cdd:COG1137 224 LNNPLVRKVYLGED 237
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-237 |
3.74e-49 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 168.54 E-value: 3.74e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiy 75
Cdd:COG1123 260 LLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSL-- 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGISRT----FQN--LQLFQAMNVFENIYSGLIhkyndsLFSVFSKskmnfdKEAREKVLEVAEMF----DIKNRltsYP 145
Cdd:COG1123 338 RELRRRvqmvFQDpySSLNPRMTVGDIIAEPLR------LHGLLSR------AERRERVAELLERVglppDLADR---YP 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 146 SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:COG1123 403 HELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQIlNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGR 482
|
250
....*....|...
gi 1341787947 225 KIAEGTPEDIANN 237
Cdd:COG1123 483 IVEDGPTEEVFAN 495
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
2-248 |
9.17e-49 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 160.52 E-value: 9.17e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:TIGR04406 2 LVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHERARLGIGYL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLIHKYndslfsvfskskmNFDKEAREKVLE-VAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:TIGR04406 82 PQEASIFRKLTVEENIMAVLEIRK-------------DLDRAEREERLEaLLEEFQISHLRDNKAMSLSGGERRRVEIAR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEV 240
Cdd:TIGR04406 149 ALATNPKFILLDEPFAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIVANEKV 228
|
....*...
gi 1341787947 241 VKVYLGED 248
Cdd:TIGR04406 229 RRVYLGEQ 236
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
3-229 |
9.18e-48 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 157.31 E-value: 9.18e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKlDTHDIIYM----GI 78
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEK-ERKRIGYVpqrrSI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFqnlqlfqAMNVFENIYSGLIHKYNdsLFSVFSKSkmnfDKEAREKVLEVAEMFDIKNRLTSypsQLTYGMLKRVEM 158
Cdd:cd03235 80 DRDF-------PISVRDVVLMGLYGHKG--LFRRLSKA----DKAKVDEALERVGLSELADRQIG---ELSGGQQQRVLL 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNfGKKIAEG 229
Cdd:cd03235 144 ARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLN-RTVVASG 213
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-234 |
3.00e-47 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 159.88 E-value: 3.00e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTH--DIIYMgi 78
Cdd:COG3842 5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEkrNVGMV-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 srtFQNLQLFQAMNVFENIYSGL-IHKyndslfsvFSKSkmnfdkEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:COG3842 83 ---FQDYALFPHLTVAENVAFGLrMRG--------VPKA------EIRARVAELLELVGLEGLADRYPHQLSGGQQQRVA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNY---YET-EEIKSIIQmvnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:COG3842 146 LARALAPEPRVLLLDEPLSALDAklrEEMrEELRRLQR---ELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEE 222
|
.
gi 1341787947 234 I 234
Cdd:COG3842 223 I 223
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
3-224 |
4.15e-46 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 153.01 E-value: 4.15e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGL--KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDII-YMGIs 79
Cdd:cd03225 1 ELKNLSFSYPDGarPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRrKVGL- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 rTFQN--LQLFqAMNVFENIYSGLIHKYNDslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:cd03225 80 -VFQNpdDQFF-GPTVEEEVAFGLENLGLP-------------EEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03225 145 IAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-244 |
4.74e-46 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 154.05 E-value: 4.74e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiymgISR 80
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRE-----LAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 T----FQNLQLFQAMNVFENIYSGLI-HKyndSLFSVFSKSkmnfDKEAREKVLEVAEMFDIKNRLTsypSQLTYGMLKR 155
Cdd:COG1120 76 RiayvPQEPPAPFGLTVRELVALGRYpHL---GLFGRPSAE----DREAVEEALERTGLEHLADRPV---DELSGGERQR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG1120 146 VLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLrRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
|
250
....*....|
gi 1341787947 235 ANNEEVVKVY 244
Cdd:COG1120 226 LTPELLEEVY 235
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-234 |
6.22e-46 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 155.27 E-value: 6.22e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYM---- 76
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDRRRIGYLpeer 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GisrtfqnlqLFQAMNVFENI-YSGLIHKYndslfsvfSKskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKR 155
Cdd:COG4152 81 G---------LYPKMKVGEQLvYLARLKGL--------SK------AEAKRRADEWLERLGLGDRANKKVEELSKGNQQK 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG4152 138 VQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI 216
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-247 |
2.45e-44 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 149.41 E-value: 2.45e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRT 81
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE---RNVGFV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLihkyndslfSVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:cd03296 80 FQHYALFRHMTVFDNVAFGL---------RVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEV 240
Cdd:cd03296 151 LAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPAS 230
|
....*....
gi 1341787947 241 VKVY--LGE 247
Cdd:cd03296 231 PFVYsfLGE 239
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-242 |
2.46e-44 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 155.57 E-value: 2.46e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:COG3845 5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDAIALGIGM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLihkynDSLFSVFskskmnFD-KEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMA 159
Cdd:COG3845 85 VHQHFMLVPNLTVAENIVLGL-----EPTKGGR------LDrKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEIL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDiANNEE 239
Cdd:COG3845 154 KALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAE-TSEEE 232
|
...
gi 1341787947 240 VVK 242
Cdd:COG3845 233 LAE 235
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-237 |
6.64e-44 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 147.77 E-value: 6.64e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRT 81
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHK---RPVNTV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:cd03300 78 FQNYALFPHLTVFENIAFGL-------------RLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETE----EIKSIIQMVnkrGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:cd03300 145 LVNEPKVLLLDEPLGALDLKLRKdmqlELKRLQKEL---GITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEE 221
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-221 |
9.93e-44 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 147.23 E-value: 9.93e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDtHDIIYMg 77
Cdd:cd03293 1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPG-PDRGYV- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 isrtFQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:cd03293 79 ----FQQDALLPWLTVLDNVALGL-------------ELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVA 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKS-IIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMN 221
Cdd:cd03293 142 LARALAVDPDVLLLDEPFSALDALTREQLQEeLLDIWRETGKTVLLVTHDIDEAVFLADRVVVLS 206
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-229 |
3.18e-43 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 145.50 E-value: 3.18e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNRIGYLPEERG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fqnlqLFQAMNVFEN-IYSGLIHKYNdslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:cd03269 81 -----LYPKMKVIDQlVYLAQLKGLK--------------KEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIA 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03269 142 AVIHDPELLILDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-210 |
3.54e-43 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 145.58 E-value: 3.54e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIY---- 75
Cdd:COG2884 1 MIRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYlrrr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGISrtFQNLQLFQAMNVFENIYSGLIhkyndslfsVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKR 155
Cdd:COG2884 81 IGVV--FQDFRLLPDRTVYENVALPLR---------VTGKSR----KEIRRRVREVLDLVGLSDKAKALPHELSGGEQQR 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVV 210
Cdd:COG2884 146 VAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELV 200
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-224 |
7.67e-43 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 144.70 E-value: 7.67e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRT 81
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD---RDIAMV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:cd03301 78 FQNYALYPHMTVYDNIAFGL-------------KLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03301 145 IVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQ 208
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-234 |
1.00e-42 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 151.59 E-value: 1.00e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF--GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVnPHK----GDILFKGESLLKLDTHdII 74
Cdd:COG1123 4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLL-PHGgrisGEVLLDGRDLLELSEA-LR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMGISRTFQN--LQLFqAMNVFENIYSGLIhkyndslfsVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:COG1123 82 GRRIGMVFQDpmTQLN-PVTVGDQIAEALE---------NLGLSR----AEARARVLELLEAVGLERRLDRYPHQLSGGQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTP 231
Cdd:COG1123 148 RQRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQReRGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPP 227
|
...
gi 1341787947 232 EDI 234
Cdd:COG1123 228 EEI 230
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
2-234 |
1.14e-42 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 147.99 E-value: 1.14e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLL-KLDTHD--IIYMgi 78
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFtNLPPRErrVGFV-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 srtFQNLQLFQAMNVFENIYSGLihkyndslfSVFSKSKmnfdKEAREKVLEVAEMF---DIKNRltsYPSQLTYGMLKR 155
Cdd:COG1118 81 ---FQHYALFPHMTVAENIAFGL---------RVRPPSK----AEIRARVEELLELVqleGLADR---YPSQLSGGQRQR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG1118 142 VALARALAVEPEVLLLDEPFGALDAKVRKELrRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEV 221
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-224 |
1.25e-42 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 142.54 E-value: 1.25e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDT---HDIIYMgi 78
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEevkRRIGYL-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 srtFQNLQLFQAMNVFENIYsglihkyndslfsvFSKskmnfdkearekvlevaemfdiknrltsypsqltyGMLKRVEM 158
Cdd:cd03230 79 ---PEEPSLYENLTVRENLK--------------LSG-----------------------------------GMKQRLAL 106
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03230 107 AQALLHDPELLILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGR 172
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-210 |
1.43e-42 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 144.17 E-value: 1.43e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDII--- 74
Cdd:cd03255 1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 --YMGIsrTFQNLQLFQAMNVFENIYSGLIhkyndslfsvFSKSKmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:cd03255 81 rrHIGF--VFQSFNLLPDLTALENVELPLL----------LAGVP---KKERRERAEELLERVGLGDRLNHYPSELSGGQ 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVV 210
Cdd:cd03255 146 QQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKeAGTTIVVVTHDPELA 204
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-248 |
9.30e-42 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 148.63 E-value: 9.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:COG1129 4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAQAAGIAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIY-------SGLIHKyndslfsvfskskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGML 153
Cdd:COG1129 84 IHQELNLVPNLSVAENIFlgreprrGGLIDW-----------------RAMRRRARELLARLGLDIDPDTPVGDLSVAQQ 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:COG1129 147 QLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAE 226
|
250
....*....|....*
gi 1341787947 234 IaNNEEVVKVYLGED 248
Cdd:COG1129 227 L-TEDELVRLMVGRE 240
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-237 |
3.19e-41 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 141.18 E-value: 3.19e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGG----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI--I 74
Cdd:cd03258 1 MIELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELrkA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMGISRTFQNLQLFQAMNVFENIYSGL-IHKYNDslfsvfskskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGML 153
Cdd:cd03258 81 RRRIGMIFQHFNLLSSRTVFENVALPLeIAGVPK--------------AEIEERVLELLELVGLEDKADAYPAQLSGGQK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPE 232
Cdd:cd03258 147 QRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVE 226
|
....*
gi 1341787947 233 DIANN 237
Cdd:cd03258 227 EVFAN 231
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-229 |
3.40e-41 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 140.72 E-value: 3.40e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYM 76
Cdd:cd03257 1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 G--ISRTFQNlqLFQAMN----VFENIYSGLIHKYNDSLfsvfskskmnfDKEAREKVLEVAEMFDI-KNRLTSYPSQLT 149
Cdd:cd03257 81 RkeIQMVFQD--PMSSLNprmtIGEQIAEPLRIHGKLSK-----------KEARKEAVLLLLVGVGLpEEVLNRYPHELS 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQ-MVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAE 228
Cdd:cd03257 148 GGQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKkLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEE 227
|
.
gi 1341787947 229 G 229
Cdd:cd03257 228 G 228
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-249 |
3.78e-41 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 141.28 E-value: 3.78e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGL-KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDT----HDIIYM 76
Cdd:cd03295 1 IEFENVTKRYGGGkKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPvelrRKIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 gisrtFQNLQLFQAMNVFENIysGLIHKYNDslfsvFSKSKmnfdkeAREKVLEVAEM--FDIKNRLTSYPSQLTYGMLK 154
Cdd:cd03295 81 -----IQQIGLFPHMTVEENI--ALVPKLLK-----WPKEK------IRERADELLALvgLDPAEFADRYPHELSGGQQQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:cd03295 143 RVGVARALAADPPLLLMDEPFGALDPITRDQLqEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDE 222
|
250
....*....|....*...
gi 1341787947 234 IANN--EEVVKVYLGEDE 249
Cdd:cd03295 223 ILRSpaNDFVAEFVGADR 240
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-234 |
4.37e-41 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 144.06 E-value: 4.37e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISR 80
Cdd:COG3839 3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKD---RNIAM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLihkyndslfsvfsksKM-NFDK-EAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEM 158
Cdd:COG3839 80 VFQSYALYPHMTVYENIAFPL---------------KLrKVPKaEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVAL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNY---YET-EEIKSIIQmvnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG3839 145 GRALVREPKVFLLDEPLSNLDAklrVEMrAEIKRLHR---RLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEEL 221
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-206 |
9.08e-41 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 140.61 E-value: 9.08e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDtHDIIYM 76
Cdd:COG1116 7 ALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPG-PDRGVV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 gisrtFQNLQLFQAMNVFENIYSGLIHKyndslfsvfSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRV 156
Cdd:COG1116 86 -----FQEPALLPWLTVLDNVALGLELR---------GVPK----AERRERARELLELVGLAGFEDAYPHQLSGGMRQRV 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNyYET-----EEIKSIIQmvnKRGKTILLVEHD 206
Cdd:COG1116 148 AIARALANDPEVLLMDEPFGALD-ALTrerlqDELLRLWQ---ETGKTVLFVTHD 198
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
2-248 |
2.01e-40 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 139.26 E-value: 2.01e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:PRK10895 4 LTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEARE-KVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:PRK10895 84 PQEASIFRRLSVYDNLMAVL-------------QIRDDLSAEQREdRANELMEEFHIEHLRDSMGQSLSGGERRRVEIAR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEV 240
Cdd:PRK10895 151 ALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHV 230
|
....*...
gi 1341787947 241 VKVYLGED 248
Cdd:PRK10895 231 KRVYLGED 238
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-234 |
9.14e-40 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 140.21 E-value: 9.14e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYM 76
Cdd:COG1135 1 MIELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 --GISRTFQNLQLFQAMNVFENI-----YSGLihkyndslfsvfSKskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLT 149
Cdd:COG1135 81 rrKIGMIFQHFNLLSSRTVAENValpleIAGV------------PK------AEIRKRVAELLELVGLSDKADAYPSQLS 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAE 228
Cdd:COG1135 143 GGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEMDVVRRICDRVAVLENGRIVEQ 222
|
....*.
gi 1341787947 229 GTPEDI 234
Cdd:COG1135 223 GPVLDV 228
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-224 |
9.72e-40 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 135.39 E-value: 9.72e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllKLDTHDIIYMGISRT 81
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGE---DLTDLEDELPPLRRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 ----FQNLQLFQAMNVFENIysglihkyndslfsvfskskmnfdkearekvlevaemfdiknrltSYPsqLTYGMLKRVE 157
Cdd:cd03229 78 igmvFQDFALFPHLTVLENI---------------------------------------------ALG--LSGGQQQRVA 110
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03229 111 LARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-244 |
2.97e-39 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 136.16 E-value: 2.97e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLK-AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI------I 74
Cdd:cd03256 1 IEVENLSKTYPNGKkALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALrqlrrqI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMgisrTFQNLQLFQAMNVFENIYSGLIHKYN--DSLFSVFSkskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:cd03256 81 GM----IFQQFNLIERLSVLENVLSGRLGRRStwRSLFGLFP-------KEEKQRALAALERVGLLDKAYQRADQLSGGQ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTP 231
Cdd:cd03256 150 QQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINReEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPP 229
|
250
....*....|...
gi 1341787947 232 EDIaNNEEVVKVY 244
Cdd:cd03256 230 AEL-TDEVLDEIY 241
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-234 |
3.66e-39 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 135.19 E-value: 3.66e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKlDTHDiIYMGISRT 81
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVR-EPRE-VRRRIGIV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYsglIHKyndSLFSVFSkskmnfdKEAREKVLEVAEMFDI---KNRLTSYPSQltyGMLKRVEM 158
Cdd:cd03265 79 FQDLSVDDELTGWENLY---IHA---RLYGVPG-------AERRERIDELLDFVGLleaADRLVKTYSG---GMRRRLEI 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQ-MVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:cd03265 143 ARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEkLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-224 |
7.55e-39 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 132.37 E-value: 7.55e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHdiiymgisrtf 82
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLE----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 83 qnlqlfqamnvfeniysglihkyndslfsvfskskmnfdkEAREKVlevaemfdiknrltSYPSQLTYGMLKRVEMARAV 162
Cdd:cd00267 70 ----------------------------------------ELRRRI--------------GYVPQLSGGQRQRVALARAL 95
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1341787947 163 ISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd00267 96 LLNPDLLLLDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
2-246 |
1.94e-38 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 134.00 E-value: 1.94e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKaVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESL--LKLDTHDIIYMgis 79
Cdd:cd03299 1 LKVENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDItnLPPEKRDISYV--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 rtFQNLQLFQAMNVFENIYSGLIHKYNDSlfsvfskskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMA 159
Cdd:cd03299 77 --PQNYALFPHMTVYKNIAYGLKKRKVDK-------------KEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIA 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI---A 235
Cdd:cd03299 142 RALVVNPKILLLDEPFSALDVRTKEKLREELKKIRKEfGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVfkkP 221
|
250
....*....|.
gi 1341787947 236 NNEEVVKvYLG 246
Cdd:cd03299 222 KNEFVAE-FLG 231
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-224 |
2.22e-38 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 133.04 E-value: 2.22e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTH-DIIYMGISR 80
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNiNELRQKVGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLIhkyndslfSVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:cd03262 81 VFQQFNLFPHLTVLENITLAPI--------KVKGMSK----AEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIAR 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03262 149 ALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGR 212
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-237 |
2.65e-38 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 133.58 E-value: 2.65e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLkLDTHDIIYMgisR 80
Cdd:COG1126 1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLT-DSKKDINKL---R 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 T-----FQNLQLFQAMNVFENIYSGLIHkyndslfsVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKR 155
Cdd:COG1126 77 RkvgmvFQQFNLFPHLTVLENVTLAPIK--------VKKMSK----AEAEERAMELLERVGLADKADAYPAQLSGGQQQR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:COG1126 145 VAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFF 224
|
..
gi 1341787947 236 NN 237
Cdd:COG1126 225 EN 226
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-229 |
3.40e-38 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 131.40 E-value: 3.40e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI-IYMGIsrt 81
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELaRKIAY--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fqnlqLFQAMnvfeniysglihkyndslfsvfskskmnfdkearekvlEVAEMFDIKNRLTsypSQLTYGMLKRVEMARA 161
Cdd:cd03214 78 -----VPQAL--------------------------------------ELLGLAHLADRPF---NELSGGERQRVLLARA 111
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03214 112 LAQEPPILLLDEPTSHLDIAHQIELLELLrRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
12-246 |
1.06e-37 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 135.37 E-value: 1.06e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 12 GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMG---ISRTFQNLQLF 88
Cdd:TIGR01186 4 GGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPVELREVRrkkIGMVFQQFALF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 89 QAMNVFENIYSGL-IHKYNDslfsvfskskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPD 167
Cdd:TIGR01186 84 PHMTILQNTSLGPeLLGWPE--------------QERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPD 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 168 LLLLDEPAAGLNYYETEEIK-SIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN--EEVVKVY 244
Cdd:TIGR01186 150 ILLMDEAFSALDPLIRDSMQdELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNpaNEYVEEF 229
|
..
gi 1341787947 245 LG 246
Cdd:TIGR01186 230 IG 231
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-234 |
1.42e-37 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 134.83 E-value: 1.42e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRT 81
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD---RKVGFV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLihkyndslfSVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:PRK10851 80 FQHYALFRHMTVFDNIAFGL---------TVLPRRERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARA 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGK-TILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK10851 151 LAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKfTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
17-176 |
1.59e-37 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 128.92 E-value: 1.59e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 17 VNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKlDTHDIIYMGISRTFQNLQLFQAMNVFEN 96
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTD-DERKSLRKEIGYVFQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 97 IYSGLIHKYNdslfsvfskSKMNFDKEArEKVLE-VAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPA 175
Cdd:pfam00005 80 LRLGLLLKGL---------SKREKDARA-EEALEkLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
.
gi 1341787947 176 A 176
Cdd:pfam00005 150 A 150
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
2-231 |
1.67e-37 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 131.09 E-value: 1.67e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGL--KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHdiIYMGIS 79
Cdd:cd03263 1 LQIRNLTKTYKKGtkPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKA--ARQSLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLFQAMNVFENIYsglihkyndslfsVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMA 159
Cdd:cd03263 79 YCPQFDALFDELTVREHLR-------------FYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLA 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTP 231
Cdd:cd03263 146 IALIGGPSVLLLDEPTSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSP 216
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-228 |
3.40e-37 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 128.32 E-value: 3.40e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGIsrt 81
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRDARRAGI--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fqnlqlfqamnvfeniysGLIHkyndslfsvfskskmnfdkearekvlevaemfdiknrltsypsQLTYGMLKRVEMARA 161
Cdd:cd03216 78 ------------------AMVY-------------------------------------------QLSVGERQMVEIARA 96
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAE 228
Cdd:cd03216 97 LARNARLLILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
16-237 |
7.22e-37 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 130.84 E-value: 7.22e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYM---GISRTFQNLQLFQAMN 92
Cdd:cd03294 39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELrrkKISMVFQSFALLPHRT 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 93 VFENIYSGLihkyndslfSVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLD 172
Cdd:cd03294 119 VLENVAFGL---------EVQGVPR----AEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMD 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 173 EPAAGLNYYETEEIKS-IIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:cd03294 186 EAFSALDPLIRREMQDeLLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTN 251
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-209 |
2.46e-36 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 128.24 E-value: 2.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFG----GLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiym 76
Cdd:COG1136 4 LLELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERE---- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 gisRT----------FQNLQLFQAMNVFENI-----YSGLIHKyndslfsvfskskmnfdkEAREKVLEVAEMFDIKNRL 141
Cdd:COG1136 80 ---LArlrrrhigfvFQFFNLLPELTALENValpllLAGVSRK------------------ERRERARELLERVGLGDRL 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 142 TSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNV 209
Cdd:COG1136 139 DHRPSQLSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPEL 207
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-234 |
3.66e-36 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 127.68 E-value: 3.66e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVN-----PHKGDILFKGESLLKLDTHDI-IY 75
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDIYDLDVDVLeLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGISRTFQNLQLFqAMNVFENIYSGL-IHKYndslfsvfsKSKMNFDKEArEKVLEVAEMFD-IKNRLTsyPSQLTYGML 153
Cdd:cd03260 81 RRVGMVFQKPNPF-PGSIYDNVAYGLrLHGI---------KLKEELDERV-EEALRKAALWDeVKDRLH--ALGLSGGQQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRgKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:cd03260 148 QRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQ 226
|
.
gi 1341787947 234 I 234
Cdd:cd03260 227 I 227
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
2-224 |
5.33e-36 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 127.14 E-value: 5.33e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYM--GI 78
Cdd:cd03292 1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLrrKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNLQLFQAMNVFENIYSGLihkyndslfSVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEM 158
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFAL---------EVTGVPP----REIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAI 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03292 148 ARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGK 213
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-237 |
5.56e-36 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 129.79 E-value: 5.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPH---KGDILFKGESLLKLDTHDI 73
Cdd:COG0444 1 LLEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPgitSGEILFDGEDLLKLSEKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 iymgisRTF--QNLQL-FQ----AMN----VFENIYSGL-IHKyndslfsVFSKskmnfdKEAREKVLEVAEMFDI---K 138
Cdd:COG0444 81 ------RKIrgREIQMiFQdpmtSLNpvmtVGDQIAEPLrIHG-------GLSK------AEARERAIELLERVGLpdpE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 139 NRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyyeteeikSIIQ---------MVNKRGKTILLVEHDMNV 209
Cdd:COG0444 142 RRLDRYPHELSGGMRQRVMIARALALEPKLLIADEPTTALD--------VTIQaqilnllkdLQRELGLAILFITHDLGV 213
|
250 260
....*....|....*....|....*...
gi 1341787947 210 VMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:COG0444 214 VAEIADRVAVMYAGRIVEEGPVEELFEN 241
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-247 |
5.06e-34 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 122.17 E-value: 5.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAvnDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISR 80
Cdd:COG3840 1 MLRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAE---RPVSM 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:COG3840 76 LFQENNLFPHLTVAQNIGLGL-------------RPGLKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALAR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI--ANN 237
Cdd:COG3840 143 CLVRKRPILLLDEPFSALDPALRQEMLDLVDELCReRGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALldGEP 222
|
250
....*....|
gi 1341787947 238 EEVVKVYLGE 247
Cdd:COG3840 223 PPALAAYLGI 232
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-229 |
1.76e-33 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 120.38 E-value: 1.76e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGkIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKldTHDIIYMGISRT 81
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLK--QPQKLRRRIGYL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENI-YSGLIHKYNdslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:cd03264 78 PQEFGVYPNFTVREFLdYIAWLKGIP--------------SKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQ 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKrGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03264 144 ALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGE-DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-248 |
5.57e-33 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 125.28 E-value: 5.57e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:PRK09700 5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSG--LIHKyndslfsVFSKSKMNFdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEM 158
Cdd:PRK09700 85 IYQELSVIDELTVLENLYIGrhLTKK-------VCGVNIIDW-REMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIAnNE 238
Cdd:PRK09700 157 AKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVS-ND 235
|
250
....*....|
gi 1341787947 239 EVVKVYLGED 248
Cdd:PRK09700 236 DIVRLMVGRE 245
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-206 |
5.96e-33 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 118.74 E-value: 5.96e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTH---DIIYMG 77
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDyrrRLAYLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 isrtfQNLQLFQAMNVFENIysglihkyndslfsVFSkSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:COG4133 82 -----HADGLKPELTVRENL--------------RFW-AALYGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVA 141
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHD 206
Cdd:COG4133 142 LARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLARGGAVLLTTHQ 190
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-229 |
6.77e-33 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 118.86 E-value: 6.77e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDThDIIYMGISRT 81
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIE-ALRRIGALIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNlqLFQAMNVFENI-YSGLIHKyndslfsvfskskmnFDKEAREKVLEVAEMFDIKNRLTsypSQLTYGMLKRVEMAR 160
Cdd:cd03268 80 APG--FYPNLTARENLrLLARLLG---------------IRKKRIDEVLDVVGLKDSAKKKV---KGFSLGMKQRLGIAL 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03268 140 ALLGNPDLLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-234 |
7.28e-33 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 123.02 E-value: 7.28e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLlkldTHDIIYM-GIS 79
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDL----SHVPPYQrPIN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLFQAMNVFENIYSGLihkYNDSLfsvfSKSKMNfdkeAR-EKVLEVAEMFDIKNRltsYPSQLTYGMLKRVEM 158
Cdd:PRK11607 95 MMFQSYALFPHMTVEQNIAFGL---KQDKL----PKAEIA----SRvNEMLGLVHMQEFAKR---KPHQLSGGQRQRVAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIK-SIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK11607 161 ARSLAKRPKLLLLDEPMGALDKKLRDRMQlEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
2-248 |
8.45e-33 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 124.64 E-value: 8.45e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:PRK11288 5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAAGVAII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSG-LIHKyndslFSVFSKSKMNfdKEAREKVLEVAEMFDIKNRLTSypsqLTYGMLKRVEMAR 160
Cdd:PRK11288 85 YQELHLVPEMTVAENLYLGqLPHK-----GGIVNRRLLN--YEAREQLEHLGVDIDPDTPLKY----LSIGQRQMVEIAK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAegTPEDIA--NNE 238
Cdd:PRK11288 154 ALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRYVA--TFDDMAqvDRD 231
|
250
....*....|
gi 1341787947 239 EVVKVYLGED 248
Cdd:PRK11288 232 QLVQAMVGRE 241
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-251 |
1.93e-32 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 120.30 E-value: 1.93e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRVGVVPQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQlfQAMNVFENIYsglihkyndslfsVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:PRK13537 88 FDNLD--PDFTVRENLL-------------VFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 162 VISDPDLLLLDEPAAGLN----YYETEEIKSIIqmvnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:PRK13537 153 LVNDPDVLVLDEPTTGLDpqarHLMWERLRSLL----ARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES 228
|
250
....*....|....*..
gi 1341787947 238 E---EVVKVYlGEDENA 251
Cdd:PRK13537 229 EigcDVIEIY-GPDPVA 244
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-236 |
4.15e-32 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 117.98 E-value: 4.15e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFG----GLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiym 76
Cdd:COG1124 1 MLEVRNLSVSYGqggrRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAF--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 gisrtFQNLQLfqamnVFENIYSGL--IHKYNDSLFSVFSKSKMnfdKEAREKVLEVAEMFDIKNR-LTSYPSQLTYGML 153
Cdd:COG1124 78 -----RRRVQM-----VFQDPYASLhpRHTVDRILAEPLRIHGL---PDREERIAELLEQVGLPPSfLDRYPHQLSGGQR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPE 232
Cdd:COG1124 145 QRVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREeRGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVA 224
|
....
gi 1341787947 233 DIAN 236
Cdd:COG1124 225 DLLA 228
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-246 |
2.75e-31 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 115.36 E-value: 2.75e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:PRK11614 5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREAVAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGlihkyndslfSVFSKSkmnfdKEAREKVLEVAEMFD-IKNRLTSYPSQLTYGMLKRVEMA 159
Cdd:PRK11614 85 VPEGRRVFSRMTVEENLAMG----------GFFAER-----DQFQERIKWVYELFPrLHERRIQRAGTMSGGEQQMLAIG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEE 239
Cdd:PRK11614 150 RALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEA 229
|
....*..
gi 1341787947 240 VVKVYLG 246
Cdd:PRK11614 230 VRSAYLG 236
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-247 |
3.47e-31 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 117.62 E-value: 3.47e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRT 81
Cdd:PRK13536 42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARARIGVVPQ 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLfqAMNVFENIYsglihkyndslfsVFSKSkmnFDKEARE------KVLEVAEMfdiKNRLTSYPSQLTYGMLKR 155
Cdd:PRK13536 122 FDNLDL--EFTVRENLL-------------VFGRY---FGMSTREieavipSLLEFARL---ESKADARVSDLSGGMKRR 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:PRK13536 181 LTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALI 260
|
250
....*....|....*
gi 1341787947 236 NNE---EVVKVYLGE 247
Cdd:PRK13536 261 DEHigcQVIEIYGGD 275
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-229 |
4.41e-31 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 114.39 E-value: 4.41e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLK----AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGesllkLDTHD---I 73
Cdd:cd03266 1 MITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG-----FDVVKepaE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 IYMGISRTFQNLQLFQAMNVFENI-YSGLIHKYNDslfsvfskskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:cd03266 76 ARRRLGFVSDSTGLYDRLTARENLeYFAGLYGLKG--------------DELTARLEELADRLGMEELLDRRVGGFSTGM 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03266 142 RQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
2-234 |
5.58e-31 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 117.13 E-value: 5.58e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLlkldTHDIIYM-GISR 80
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDV----THRSIQQrDICM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLihkyndslfsvfsksKM-NFDK-EAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEM 158
Cdd:PRK11432 83 VFQSYALFPHMSLGENVGYGL---------------KMlGVPKeERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVAL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 159 ARAVISDPDLLLLDEPA----AGLNYYETEEIKSIIQMVNkrgKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK11432 148 ARALILKPKVLLFDEPLsnldANLRRSMREKIRELQQQFN---ITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQEL 224
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-238 |
1.56e-30 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 113.64 E-value: 1.56e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKiH-ALIGPNGAGKTTLFNTITRIVNPHKG---DIL---FKGESLLKLDTHdi 73
Cdd:COG1119 3 LLELRNVTVRRGGKTILDDISWTVKPGE-HwAILGPNGAGKSTLLSLITGDLPPTYGndvRLFgerRGGEDVWELRKR-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 iyMGISRTFQNLQLFQAMNVFENIYSGLihkyNDS--LFsvfskskMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYG 151
Cdd:COG1119 80 --IGLVSPALQLRFPRDETVLDVVLSGF----FDSigLY-------REPTDEQRERARELLELLGLAHLADRPFGTLSQG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 152 MLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHdmnvvmNVSDL------VTVMNFGK 224
Cdd:COG1119 147 EQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLdKLAAEGAPTLVLVTH------HVEEIppgithVLLLKDGR 220
|
250
....*....|....
gi 1341787947 225 KIAEGTPEDIANNE 238
Cdd:COG1119 221 VVAAGPKEEVLTSE 234
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-237 |
3.38e-30 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 112.49 E-value: 3.38e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLL--KLDTHDI-IYMG 77
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpKVDERLIrQEAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 IsrTFQNLQLFQAMNVFENIYSGLIHkyndslfsVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK09493 81 M--VFQQFYLFPHLTALENVMFGPLR--------VRGASK----EEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:PRK09493 147 IARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKN 226
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1-239 |
4.00e-30 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 113.32 E-value: 4.00e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI--IYMGI 78
Cdd:PRK11831 7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLytVRKRM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEA-REKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK11831 87 SMLFQSGALFTDMNVFDNVAYPL-------------REHTQLPAPLlHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIAN 236
Cdd:PRK11831 154 LARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQA 233
|
...
gi 1341787947 237 NEE 239
Cdd:PRK11831 234 NPD 236
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-224 |
8.55e-30 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 109.39 E-value: 8.55e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG--LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgIS 79
Cdd:cd03228 1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKN-IA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLFqAMNVFENIYSGlihkyndslfsvfskskmnfdkearekvlevaemfdiknrltsypsqltyGMLKRVEMA 159
Cdd:cd03228 80 YVPQDPFLF-SGTIRENILSG--------------------------------------------------GQRQRIAIA 108
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNyYETEEIksIIQMVNK--RGKTILLVEHDMNVVMNVsDLVTVMNFGK 224
Cdd:cd03228 109 RALLRDPPILILDEATSALD-PETEAL--ILEALRAlaKGKTVIVIAHRLSTIRDA-DRIIVLDDGR 171
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
2-234 |
1.29e-29 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 116.47 E-value: 1.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLK--AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI-IYMGI 78
Cdd:COG2274 474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLrRQIGV 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SrtFQNLQLFQAmNVFENIysglihkyndslfsVFSKSKMNFdkearEKVLEVAEMFDIKNRLTSYP-----------SQ 147
Cdd:COG2274 554 V--LQDVFLFSG-TIRENI--------------TLGDPDATD-----EEIIEAARLAGLHDFIEALPmgydtvvgeggSN 611
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyYETEEIksIIQMVNK--RGKTILLVEHDMNVVMNVsDLVTVMNFGKK 225
Cdd:COG2274 612 LSGGQRQRLAIARALLRNPRILILDEATSALD-AETEAI--ILENLRRllKGRTVIIIAHRLSTIRLA-DRIIVLDKGRI 687
|
....*....
gi 1341787947 226 IAEGTPEDI 234
Cdd:COG2274 688 VEDGTHEEL 696
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-234 |
1.96e-29 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 113.50 E-value: 1.96e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRT 81
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAEN---RHVNTV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLihkyndslfsvfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:PRK09452 92 FQSYALFPHMTVFENVAFGL-------------RMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARA 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKS-IIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK09452 159 VVNKPKVLLLDESLSALDYKLRKQMQNeLKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREI 232
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-238 |
3.30e-29 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 110.17 E-value: 3.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDII-YMGIS 79
Cdd:COG4604 1 MIEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAkRLAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RtfQNLQLFQAMNVFEniysgLIhkyndsLFSVFSKSKMNFDKEAREKV---LEVAEMFDIKNRltsYPSQLTYGMLKRV 156
Cdd:COG4604 81 R--QENHINSRLTVRE-----LV------AFGRFPYSKGRLTAEDREIIdeaIAYLDLEDLADR---YLDELSGGQRQRA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPaagLN----YYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPE 232
Cdd:COG4604 145 FIAMVLAQDTDYVLLDEP---LNnldmKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPE 221
|
....*.
gi 1341787947 233 DIANNE 238
Cdd:COG4604 222 EIITPE 227
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-227 |
5.45e-29 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 113.87 E-value: 5.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRiVNPH---KGDILFKGESLLKLDTHDIIYMG 77
Cdd:PRK13549 5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYPHgtyEGEIIFEGEELQASNIRDTERAG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQLFQAMNVFENIYSGL-IHKYndslfsvfskSKMNFDK---EAREKVLEVAEMFDIKNRLtsypSQLTYGML 153
Cdd:PRK13549 84 IAIIHQELALVKELSVLENIFLGNeITPG----------GIMDYDAmylRAQKLLAQLKLDINPATPV----GNLGLGQQ 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIA 227
Cdd:PRK13549 150 QLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGRHIG 223
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-234 |
7.70e-29 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 111.43 E-value: 7.70e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGG----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI--- 73
Cdd:PRK11153 1 MIELKNISKVFPQggrtIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELrka 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 ---IYMgisrTFQNLQLFQAMNVFENIYSGLihkyndslfSVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTY 150
Cdd:PRK11153 81 rrqIGM----IFQHFNLLSSRTVFDNVALPL---------ELAGTPK----AEIKARVTELLELVGLSDKADRYPAQLSG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:PRK11153 144 GQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQG 223
|
....*
gi 1341787947 230 TPEDI 234
Cdd:PRK11153 224 TVSEV 228
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
2-241 |
1.12e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 109.44 E-value: 1.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgISR 80
Cdd:PRK13647 5 IEVEDLHFRYkDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSK-VGL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNL--QLFqAMNVFENIYSGLIhkyNDSLfsvfSKSKMNfdkEAREKVLEVAEMFDIKNRLtsyPSQLTYGMLKRVEM 158
Cdd:PRK13647 84 VFQDPddQVF-SSTVWDDVAFGPV---NMGL----DKDEVE---RRVEEALKAVRMWDFRDKP---PYHLSYGQKKRVAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEdIANNE 238
Cdd:PRK13647 150 AGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS-LLTDE 228
|
...
gi 1341787947 239 EVV 241
Cdd:PRK13647 229 DIV 231
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-244 |
1.14e-28 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 108.95 E-value: 1.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiymgISR 80
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQ-----LAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TF----QNLQLFQAMNVFENIYSGLiHKYNdSLFSVFSKSkmnfDKEAREKVLEVAEMFDIKNRLTsypSQLTYGMLKRV 156
Cdd:PRK11231 77 RLallpQHHLTPEGITVRELVAYGR-SPWL-SLWGRLSAE----DNARVNQAMEQTRINHLADRRL---TDLSGGQRQRA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIAN 236
Cdd:PRK11231 148 FLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMT 227
|
....*...
gi 1341787947 237 NEEVVKVY 244
Cdd:PRK11231 228 PGLLRTVF 235
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-237 |
1.30e-28 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 108.85 E-value: 1.30e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPH-----KGDILFKGESLLKLDTHDIiYM 76
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYpearvSGEVYLDGQDIFKMDVIEL-RR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQNLQLFQAMNVFENIYSGLihKYNDslfsvFSKSKMNFDKEAREkVLEVAEMFD-IKNRLTSYPSQLTYGMLKR 155
Cdd:PRK14247 83 RVQMVFQIPNPIPNLSIFENVALGL--KLNR-----LVKSKKELQERVRW-ALEKAQLWDeVKDRLDAPAGKLSGGQQQR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:PRK14247 155 LCIARALAFQPEVLLADEPTANLDPENTAKIESLFLEL-KKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVF 233
|
..
gi 1341787947 236 NN 237
Cdd:PRK14247 234 TN 235
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-241 |
1.61e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 108.92 E-value: 1.61e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLK--AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKlDTHDIIYMGI 78
Cdd:PRK13632 7 MIKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK-ENLKEIRKKI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNL-QLFQAMNVFENIYSGLIHKyndslfsVFSKSKMnfdkeaREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK13632 86 GIIFQNPdNQFIGATVEDDIAFGLENK-------KVPPKKM------KDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDIAN 236
Cdd:PRK13632 153 IASVLALNPEIIIFDESTSMLDPKGKREIKKIMvDLRKTRKKTLISITHDMDEAIL-ADKVIVFSEGKLIAQGKPKEILN 231
|
....*
gi 1341787947 237 NEEVV 241
Cdd:PRK13632 232 NKEIL 236
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
16-237 |
2.10e-28 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 111.28 E-value: 2.10e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKL---DTHDIIYMGISRTFQNLQLFQAMN 92
Cdd:PRK10070 43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKIsdaELREVRRKKIAMVFQSFALMPHMT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 93 VFENIYSGLihkyndSLFSVFSKskmnfdkEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLD 172
Cdd:PRK10070 123 VLDNTAFGM------ELAGINAE-------ERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMD 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 173 EPAAGLN-YYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANN 237
Cdd:PRK10070 190 EAFSALDpLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNN 255
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1-242 |
4.00e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 108.24 E-value: 4.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLlKLDTHDII----Y 75
Cdd:PRK13639 1 ILETRDLKYSYpDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPI-KYDKKSLLevrkT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGIsrTFQNL--QLFqAMNVFENIysglihkyndslfsVFSKSKMNFDKEAREK-VLEVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:PRK13639 80 VGI--VFQNPddQLF-APTVEEDV--------------AFGPLNLGLSKEEVEKrVKEALKAVGMEGFENKPPHHLSGGQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPE 232
Cdd:PRK13639 143 KKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPK 222
|
250
....*....|
gi 1341787947 233 DIANNEEVVK 242
Cdd:PRK13639 223 EVFSDIETIR 232
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-227 |
1.07e-27 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 110.30 E-value: 1.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIvNPH---KGDILFKGESLLKLDTHDIIYMG 77
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHgtwDGEIYWSGSPLKASNIRDTERAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQLFQAMNVFENIYSG--LIHKyndslfsvfsKSKMNFDKEAR--EKVLEVAEMFDIKNrlTSYPSQLTYGML 153
Cdd:TIGR02633 80 IVIIHQELTLVPELSVAENIFLGneITLP----------GGRMAYNAMYLraKNLLRELQLDADNV--TRPVGDYGGGQQ 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIA 227
Cdd:TIGR02633 148 QLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVA 221
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
16-229 |
2.16e-27 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 105.11 E-value: 2.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGesLLKLDTHDIIYMGISRTF-QNLQLFQAMNVF 94
Cdd:cd03267 36 ALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG--LVPWKRRKKFLRRIGVVFgQKTQLWWDLPVI 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 95 ENiYSGLIHKYNDSlfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEP 174
Cdd:cd03267 114 DS-FYLLAAIYDLP------------PARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEP 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 175 AAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03267 181 TIGLDVVAQENIRNFLKEYNReRGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
19-229 |
2.18e-27 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 104.68 E-value: 2.18e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITIS---QGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLklDTHDIIYM-----GISRTFQNLQLFQA 90
Cdd:cd03297 12 DFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLF--DSRKKINLppqqrKIGLVFQQYALFPH 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 91 MNVFENIYSGLihkyndslfsvfsksKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLL 170
Cdd:cd03297 90 LNVRENLAFGL---------------KRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 171 LDEPAAGLNyyetEEIKSIIQ-MVNKRGK----TILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03297 155 LDEPFSALD----RALRLQLLpELKQIKKnlniPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-242 |
4.85e-27 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 105.31 E-value: 4.85e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFG-GLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLlkldthDIIYMGIS 79
Cdd:PRK13636 5 ILKVEELNYNYSdGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPI------DYSRKGLM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLfqamnVFENIYSGLihkYNDSLFSVFSKSKMNF---DKEAREKVLEVAEMFDIKNrLTSYPSQ-LTYGMLKR 155
Cdd:PRK13636 79 KLRESVGM-----VFQDPDNQL---FSASVYQDVSFGAVNLklpEDEVRKRVDNALKRTGIEH-LKDKPTHcLSFGQKKR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK13636 150 VAIAGVLVMEPKVLVLDEPTAGLDPMGVSEImKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV 229
|
....*...
gi 1341787947 235 ANNEEVVK 242
Cdd:PRK13636 230 FAEKEMLR 237
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
3-224 |
6.77e-27 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 103.11 E-value: 6.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFG-GLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgisrT 81
Cdd:cd03226 1 RIENISFSYKkGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRKSIGY----V 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNL--QLFQAmNVFENIYSGLIHKYNdslfsvfskskmnfDKEAREKVLEVAEMFDIKNRltsYPSQLTYGMLKRVEMA 159
Cdd:cd03226 77 MQDVdyQLFTD-SVREELLLGLKELDA--------------GNEQAETVLKDLDLYALKER---HPLSLSGGQKQRLAIA 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:cd03226 139 AALLSGKDLLIFDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGA 203
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-233 |
9.64e-27 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 107.92 E-value: 9.64e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHD----IIYM 76
Cdd:COG4988 337 IELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASwrrqIAWV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GisrtfQNLQLFQAmNVFENIysglihkyndsLFsvfskSKMNFDKEAREKVLEVAEMFDIKNRLtsyPSQLTY------ 150
Cdd:COG4988 417 P-----QNPYLFAG-TIRENL-----------RL-----GRPDASDEELEAALEAAGLDEFVAAL---PDGLDTplgegg 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 -----GMLKRVEMARAVISDPDLLLLDEPAAGLNyYETEEIksIIQMVNK--RGKTILLVEHDMNVVMNvSDLVTVMNFG 223
Cdd:COG4988 472 rglsgGQAQRLALARALLRDAPLLLLDEPTAHLD-AETEAE--ILQALRRlaKGRTVILITHRLALLAQ-ADRILVLDDG 547
|
250
....*....|
gi 1341787947 224 KKIAEGTPED 233
Cdd:COG4988 548 RIVEQGTHEE 557
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-244 |
2.09e-26 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 102.89 E-value: 2.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiymgISR 80
Cdd:COG4559 1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWE-----LAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TF----QNLQLFQAMNVFENIYSGLIHKYNDSLfsvfskskmnFDKEAREKVLEVAEMFDIKNRltSYPsQLTYGMLKRV 156
Cdd:COG4559 76 RRavlpQHSSLAFPFTVEEVVALGRAPHGSSAA----------QDRQIVREALALVGLAHLAGR--SYQ-TLSGGEQQRV 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARA-------VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:COG4559 143 QLARVlaqlwepVDGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQG 222
|
250
....*....|....*
gi 1341787947 230 TPEDIANNEEVVKVY 244
Cdd:COG4559 223 TPEEVLTDELLERVY 237
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-241 |
2.97e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 103.34 E-value: 2.97e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiymgis 79
Cdd:PRK13652 3 LIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREV------ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLqlfqamnVFENiysglihkYNDSLFS-------VFSKSKMNFDKEARE-KVLEVAEMFDIKNRLTSYPSQLTYG 151
Cdd:PRK13652 77 RKFVGL-------VFQN--------PDDQIFSptveqdiAFGPINLGLDEETVAhRVSSALHMLGLEELRDRVPHHLSGG 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 152 MLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGT 230
Cdd:PRK13652 142 EKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGT 221
|
250
....*....|.
gi 1341787947 231 PEDIANNEEVV 241
Cdd:PRK13652 222 VEEIFLQPDLL 232
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-239 |
1.22e-25 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 101.07 E-value: 1.22e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIV--NPH---KGDILFKGESLLKLDTHDI-IY 75
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLelNEEarvEGEVRLFGRNIYSPDVDPIeVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGISRTFQNLQLFQAMNVFENIYSGLihKYNDslfsvFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKR 155
Cdd:PRK14267 85 REVGMVFQYPNPFPHLTIYDNVAIGV--KLNG-----LVKSKKELDERVEWALKKAALWDEVKDRLNDYPSNLSGGQRQR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:PRK14267 158 LVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFEL-KKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVF 236
|
....
gi 1341787947 236 NNEE 239
Cdd:PRK14267 237 ENPE 240
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
2-233 |
1.27e-25 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 102.50 E-value: 1.27e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF---GGL--------KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDT 70
Cdd:COG4608 8 LEVRDLKKHFpvrGGLfgrtvgvvKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 71 HDIiymgisRTF-QNLQLfqamnVFENIYSGL---------------IHKyndslfsVFSKskmnfdKEAREKVLEVAEM 134
Cdd:COG4608 88 REL------RPLrRRMQM-----VFQDPYASLnprmtvgdiiaeplrIHG-------LASK------AERRERVAELLEL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 135 FDIK----NRltsYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyyeteeiKSI-IQMVN-------KRGKTILL 202
Cdd:COG4608 144 VGLRpehaDR---YPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALD-------VSIqAQVLNlledlqdELGLTYLF 213
|
250 260 270
....*....|....*....|....*....|.
gi 1341787947 203 VEHDMNVVMNVSDLVTVMNFGkKIAEGTPED 233
Cdd:COG4608 214 ISHDLSVVRHISDRVAVMYLG-KIVEIAPRD 243
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-237 |
5.53e-25 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 99.27 E-value: 5.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLL-------KLDTHDII 74
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgQLKVADKN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMGISRT-----FQNLQLFQAMNVFENIYSGLIHkyndslfsVFSKSKmnfdKEAREKVLEVAEMFDIKNRLT-SYPSQL 148
Cdd:PRK10619 86 QLRLLRTrltmvFQHFNLWSHMTVLENVMEAPIQ--------VLGLSK----QEARERAVKYLAKVGIDERAQgKYPVHL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 149 TYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAE 228
Cdd:PRK10619 154 SGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEE 233
|
....*....
gi 1341787947 229 GTPEDIANN 237
Cdd:PRK10619 234 GAPEQLFGN 242
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-237 |
1.85e-24 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 97.80 E-value: 1.85e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRI--VNP---HKGDILFKGESLLKLDThDIIYM 76
Cdd:COG1117 12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMndLIPgarVEGEILLDGEDIYDPDV-DVVEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 gisRT-----FQNLQLFqAMNVFENIYSGL-IHKYNDslfsvfsKSKMNfdkEAREKVLEVAEMFD-IKNRLTSYPSQLT 149
Cdd:COG1117 91 ---RRrvgmvFQKPNPF-PKSIYDNVAYGLrLHGIKS-------KSELD---EIVEESLRKAALWDeVKDRLKKSALGLS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRgKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:COG1117 157 GGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD-YTIVIVTHNMQQAARVSDYTAFFYLGELVEFG 235
|
....*...
gi 1341787947 230 TPEDIANN 237
Cdd:COG1117 236 PTEQIFTN 243
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
2-239 |
2.59e-24 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 101.00 E-value: 2.59e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF--GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiymgiS 79
Cdd:COG4987 334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDL-----R 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTF----QNLQLFqAMNVFENIysgLIhkyndslfsvfskskmnfdkeAR-----EKVLEVAEMFDIKNRLTSYP----- 145
Cdd:COG4987 409 RRIavvpQRPHLF-DTTLRENL---RL---------------------ARpdatdEELWAALERVGLGDWLAALPdgldt 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 146 ------SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyYETEeiKSIIQMVNK--RGKTILLVEHDMnVVMNVSDLV 217
Cdd:COG4987 464 wlgeggRRLSGGERRRLALARALLRDAPILLLDEPTEGLD-AATE--QALLADLLEalAGRTVLLITHRL-AGLERMDRI 539
|
250 260
....*....|....*....|..
gi 1341787947 218 TVMNFGKKIAEGTPEDIANNEE 239
Cdd:COG4987 540 LVLEDGRIVEQGTHEELLAQNG 561
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
1-234 |
2.62e-24 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 99.40 E-value: 2.62e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVkNVTVTFGGLKAvnDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLklDTHDIIYM---- 76
Cdd:COG4148 2 MLEV-DFRLRRGGFTL--DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQ--DSARGIFLpphr 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 -GISRTFQNLQLFQAMNVFENIYSGliHKyndslFSVFSKSKMNFDkearekvlEVAEMFDIKNRLTSYPSQLTYGMLKR 155
Cdd:COG4148 77 rRIGYVFQEARLFPHLSVRGNLLYG--RK-----RAPRAERRISFD--------EVVELLGIGHLLDRRPATLSGGERQR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKT-ILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG4148 142 VAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDELDIpILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEV 221
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-229 |
5.84e-24 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 96.36 E-value: 5.84e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDI------------LFKGESLLK- 67
Cdd:PRK11264 3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditidtarsLSQQKGLIRq 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 68 LDTHdiiymgISRTFQNLQLFQAMNVFENIYSG-LIHKyndslfsvfskskmnfdKEAREKVLEVAEMFDIKNRLT---- 142
Cdd:PRK11264 83 LRQH------VGFVFQNFNLFPHRTVLENIIEGpVIVK-----------------GEPKEEATARARELLAKVGLAgket 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 143 SYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNF 222
Cdd:PRK11264 140 SYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQ 219
|
....*..
gi 1341787947 223 GKKIAEG 229
Cdd:PRK11264 220 GRIVEQG 226
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-242 |
6.73e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 97.46 E-value: 6.73e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG-----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILF---------KGESLLK 67
Cdd:PRK13651 3 IKVKNIVKIFNKklpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkdeknkkKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 68 LDTHDIIYMGISRTFQNLQLF--QAMNVFE----NIYSGLIHKynDSLFSVFSkskMNFDK-EAREKVLEVAEMFDI-KN 139
Cdd:PRK13651 83 VLEKLVIQKTRFKKIKKIKEIrrRVGVVFQfaeyQLFEQTIEK--DIIFGPVS---MGVSKeEAKKRAAKYIELVGLdES 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 140 RLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTV 219
Cdd:PRK13651 158 YLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIF 237
|
250 260
....*....|....*....|...
gi 1341787947 220 MNFGKKIAEGTPEDIANNEEVVK 242
Cdd:PRK13651 238 FKDGKIIKDGDTYDILSDNKFLI 260
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-240 |
7.48e-24 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 96.31 E-value: 7.48e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDIlfkgesllKLDTHDIIYMGISR 80
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSI--------TLDGKPVEGPGAER 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 --TFQNLQLFQAMNVFENIYSGLihkyndSLFSVfskskmnfDKEAREKV-LEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK11248 73 gvVFQNEGLLPWRNVQDNVAFGL------QLAGV--------EKMQRLEIaHQMLKKVGLEGAEKRYIWQLSGGQRQRVG 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKS-IIQMVNKRGKTILLVEHDM-NVVMNVSDLVTV------------MNFG 223
Cdd:PRK11248 139 IARALAANPQLLLLDEPFGALDAFTREQMQTlLLKLWQETGKQVLLITHDIeEAVFMATELVLLspgpgrvverlpLNFA 218
|
250 260
....*....|....*....|....*
gi 1341787947 224 KKIAEGT--------PEDIANNEEV 240
Cdd:PRK11248 219 RRFVAGEssrsiksdPQFIAMREYV 243
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
2-232 |
9.00e-24 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 94.52 E-value: 9.00e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTI-----TRIVnphKGDILFKGESLLKLDTHDIIYM 76
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTImghpkYEVT---EGEILFKGEDITDLPPEERARL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQNLQLFQAMNVfeniysglihkyndslfsvfskskMNFdkearekVLEVAEMFdiknrltsypsqlTYGMLKRV 156
Cdd:cd03217 78 GIFLAFQYPPEIPGVKN------------------------ADF-------LRYVNEGF-------------SGGEKKRN 113
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVV-MNVSDLVTVMNFGKKIAEGTPE 232
Cdd:cd03217 114 EILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREEGKSVLIITHYQRLLdYIKPDRVHVLYDGRIVKSGDKE 190
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-234 |
1.46e-23 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 98.60 E-value: 1.46e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLK----AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIV--NPHK--GDILFKGESLLKLDTHD 72
Cdd:COG4172 6 LLSVEDLSVAFGQGGgtveAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLpdPAAHpsGSILFDGQDLLGLSERE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 73 I-------IYMgisrtfqnlqLFQ--------AMNVFENIYSGL-IHKyndslfsvfsksKMNfDKEAREKVLEVAEMFD 136
Cdd:COG4172 86 LrrirgnrIAM----------IFQepmtslnpLHTIGKQIAEVLrLHR------------GLS-GAAARARALELLERVG 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 137 IKN---RLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNKRGKTILLVEHDMNVVMN 212
Cdd:COG4172 143 IPDperRLDAYPHQLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQIlDLLKDLQRELGMALLLITHDLGVVRR 222
|
250 260
....*....|....*....|..
gi 1341787947 213 VSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG4172 223 FADRVAVMRQGEIVEQGPTAEL 244
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1-234 |
3.45e-23 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 97.57 E-value: 3.45e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNV-----TVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFK-GESLLKLDTHDII 74
Cdd:TIGR03269 279 IIKVRNVskryiSVDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvGDEWVDMTKPGPD 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 -------YMGIsrTFQNLQLFQAMNVFENIYSGLIHKYNDSLF---SVFSKSKMNFDKEAREKVLEvaemfdiknrltSY 144
Cdd:TIGR03269 359 grgrakrYIGI--LHQEYDLYPHRTVLDNLTEAIGLELPDELArmkAVITLKMVGFDEEKAEEILD------------KY 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 145 PSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFG 223
Cdd:TIGR03269 425 PDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVtHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDG 504
|
250
....*....|.
gi 1341787947 224 KKIAEGTPEDI 234
Cdd:TIGR03269 505 KIVKIGDPEEI 515
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-206 |
4.34e-23 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 94.16 E-value: 4.34e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLK----AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfkgesllkLDTHDIIYM 76
Cdd:COG4525 3 MLTVRHVSVRYPGGGqpqpALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEIT--------LDGVPVTGP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISR--TFQNLQLFQAMNVFENIYSGLihkyndslfsvfsksKMN-FDKEAREKV-LEVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:COG4525 75 GADRgvVFQKDALLPWLNVLDNVAFGL---------------RLRgVPKAERRARaEELLALVGLADFARRRIWQLSGGM 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHD 206
Cdd:COG4525 140 RQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRtGKGVFLITHS 194
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-238 |
8.94e-23 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 96.27 E-value: 8.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGG---LKAVnDFsiTISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMG 77
Cdd:PRK15439 11 LLCARSISKQYSGvevLKGI-DF--TLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHQLG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQLFQAMNVFENIYSGLiHKYNDslfsvfSKSKM---------NFDKEAREKVLEVAEmfdiknrltsypSQL 148
Cdd:PRK15439 88 IYLVPQEPLLFPNLSVKENILFGL-PKRQA------SMQKMkqllaalgcQLDLDSSAGSLEVAD------------RQI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 149 tygmlkrVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAE 228
Cdd:PRK15439 149 -------VEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALS 221
|
250
....*....|
gi 1341787947 229 GTPEDIANNE 238
Cdd:PRK15439 222 GKTADLSTDD 231
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-245 |
9.26e-23 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 93.22 E-value: 9.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-------GGLK---------------AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDI 58
Cdd:COG1134 4 MIEVENVSKSYrlyhepsRSLKelllrrrrtrreefwALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 59 LFKGE--SLLkldthdiiymGISRTFQNlqlfqAMNVFENIY-SGLIHKyndslfsvFSKSKMnfdKEAREKVLEVAEM- 134
Cdd:COG1134 84 EVNGRvsALL----------ELGAGFHP-----ELTGRENIYlNGRLLG--------LSRKEI---DEKFDEIVEFAELg 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 135 --FD--IKNrltsYPSqltyGMLKRVEMARAVISDPDLLLLDEP-AAG-LNYYEteeiKSI--IQMVNKRGKTILLVEHD 206
Cdd:COG1134 138 dfIDqpVKT----YSS----GMRARLAFAVATAVDPDILLVDEVlAVGdAAFQK----KCLarIRELRESGRTVIFVSHS 205
|
250 260 270
....*....|....*....|....*....|....*....
gi 1341787947 207 MNVVMNVSDLVTVMNFGKKIAEGTPediannEEVVKVYL 245
Cdd:COG1134 206 MGAVRRLCDRAIWLEKGRLVMDGDP------EEVIAAYE 238
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
15-247 |
1.15e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 93.74 E-value: 1.15e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGE---------SLLKLDTHdiiyMGISRTFQNL 85
Cdd:PRK13641 21 KGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYhitpetgnkNLKKLRKK----VSLVFQFPEA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 86 QLFQAmNVFENIYSGlihkyndslfsvfsksKMNF---DKEAREKVLEVAEMFDIKNRLTSY-PSQLTYGMLKRVEMARA 161
Cdd:PRK13641 97 QLFEN-TVLKDVEFG----------------PKNFgfsEDEAKEKALKWLKKVGLSEDLISKsPFELSGGQMRRVAIAGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI-ANNEEV 240
Cdd:PRK13641 160 MAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIfSDKEWL 239
|
....*..
gi 1341787947 241 VKVYLGE 247
Cdd:PRK13641 240 KKHYLDE 246
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-215 |
1.62e-22 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 92.53 E-value: 1.62e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRI--VNPH---KGDILFKGESLL--KLDTHDi 73
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndLNPEvtiTGSIVYNGHNIYspRTDTVD- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 IYMGISRTFQNLQLFqAMNVFENIYSGLihkyndSLFSVFSKSKMNfdkEAREKVLEVAEMFD-IKNRLTSYPSQLTYGM 152
Cdd:PRK14239 84 LRKEIGMVFQQPNPF-PMSIYENVVYGL------RLKGIKDKQVLD---EAVEKSLKGASIWDeVKDRLHDSALGLSGGQ 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNVSD 215
Cdd:PRK14239 154 QQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGL-KDDYTMLLVTRSMQQASRISD 215
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
19-229 |
2.16e-22 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 91.40 E-value: 2.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRTFQNLQLFQAMNVFENIY 98
Cdd:cd03298 16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPAD---RPVSMLFQENNLFAHLTVEQNVG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 99 SGLihkyNDSLfsvfsksKMNfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGL 178
Cdd:cd03298 93 LGL----SPGL-------KLT--AEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAAL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1341787947 179 NYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03298 160 DPALRAEMLDLVLDLHAeTKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
4-244 |
2.63e-22 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 92.16 E-value: 2.63e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 4 VKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDT----HDIIYMGis 79
Cdd:PRK10575 14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSkafaRKVAYLP-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 rtfQNLQLFQAMNVFENIYSGLiHKYNDSLfsvfskskMNFDKEAREKVLEVAEMFDIK---NRLTSypsQLTYGMLKRV 156
Cdd:PRK10575 92 ---QQLPAAEGMTVRELVAIGR-YPWHGAL--------GRFGAADREKVEEAISLVGLKplaHRLVD---SLSGGERQRA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQ-MVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:PRK10575 157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHrLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELM 236
|
....*....
gi 1341787947 236 NNEEVVKVY 244
Cdd:PRK10575 237 RGETLEQIY 245
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
15-242 |
3.15e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 92.42 E-value: 3.15e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLL--KLDTHDI-IYMGISRTFQNLQLFQam 91
Cdd:PRK13637 21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITdkKVKLSDIrKKVGLVFQYPEYQLFE-- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 92 nvfENIYSGLihkyndslfsVFSKSKMNF-DKEAREKVLEVAEMF-----DIKNRltsYPSQLTYGMLKRVEMARAVISD 165
Cdd:PRK13637 99 ---ETIEKDI----------AFGPINLGLsEEEIENRVKRAMNIVgldyeDYKDK---SPFELSGGQKRRVAIAGVVAME 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 166 PDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGK-TILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEVVK 242
Cdd:PRK13637 163 PKILILDEPTAGLDPKGRDEILNKIKELHKEYNmTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKEVETLE 240
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-220 |
3.75e-22 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 94.66 E-value: 3.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG-LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiIYMGISR 80
Cdd:TIGR02857 322 LEFSGVSVAYPGrRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADS-WRDQIAW 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAmNVFENIYSGLihkyNDSlfsvfskskmnfDKEAREKVLEVAEMFD--------IKNRLTSYPSQLTYGM 152
Cdd:TIGR02857 401 VPQHPFLFAG-TIAENIRLAR----PDA------------SDAEIREALERAGLDEfvaalpqgLDTPIGEGGAGLSGGQ 463
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNyYETE-EIKSIIQMVnKRGKTILLVEHDMNVVMNVsDLVTVM 220
Cdd:TIGR02857 464 AQRLALARAFLRDAPLLLLDEPTAHLD-AETEaEVLEALRAL-AQGRTVLLVTHRLALAALA-DRIVVL 529
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
3-232 |
4.81e-22 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 90.75 E-value: 4.81e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgISRT 81
Cdd:cd03254 4 EFENVNFSYdEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSM-IGVV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAmNVFENIysglihKYNDSlfsvfskskmNFDKEAREKVLEVAEMFDIKNRLTS-YPSQ-------LTYGML 153
Cdd:cd03254 83 LQDTFLFSG-TIMENI------RLGRP----------NATDEEVIEAAKEAGAHDFIMKLPNgYDTVlgenggnLSQGER 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNyYETEE-IKSIIQMVNKrGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPE 232
Cdd:cd03254 146 QLLAIARAMLRDPKILILDEATSNID-TETEKlIQEALEKLMK-GRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTHD 222
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
5-248 |
6.60e-22 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 94.03 E-value: 6.60e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 5 KNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISRTFQN 84
Cdd:PRK10982 2 SNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEALENGISMVHQE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 85 LQLFQAMNVFENIYSGlihKYNDSLFSVfSKSKMNFDKEAREKVLEVaemfDIKNRLTSypSQLTYGMLKRVEMARAVIS 164
Cdd:PRK10982 82 LNLVLQRSVMDNMWLG---RYPTKGMFV-DQDKMYRDTKAIFDELDI----DIDPRAKV--ATLSVSQMQMIEIAKAFSY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 165 DPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIaNNEEVVKVY 244
Cdd:PRK10982 152 NAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAGL-TMDKIIAMM 230
|
....
gi 1341787947 245 LGED 248
Cdd:PRK10982 231 VGRS 234
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
14-242 |
6.81e-22 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 91.22 E-value: 6.81e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 14 LKAVN-DFSITISQGkihaLIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLlkldthDIIYMGISRTFQnlqlfQAMN 92
Cdd:PRK13638 17 LKGLNlDFSLSPVTG----LVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPL------DYSKRGLLALRQ-----QVAT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 93 VFENIYSGLIHKYNDSLFSvFSKSKMNF-DKEAREKVLEVAEMFDIKnRLTSYPSQ-LTYGMLKRVEMARAVISDPDLLL 170
Cdd:PRK13638 82 VFQDPEQQIFYTDIDSDIA-FSLRNLGVpEAEITRRVDEALTLVDAQ-HFRHQPIQcLSHGQKKRVAIAGALVLQARYLL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1341787947 171 LDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEVVK 242
Cdd:PRK13638 160 LDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACTEAME 231
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
1-237 |
7.51e-22 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 92.28 E-value: 7.51e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPH---KGDIL-FKGESLLKLDTHD 72
Cdd:COG4170 3 LLDIRNLTIEIdtpqGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwhvTADRFrWNGIDLLKLSPRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 73 ---IIYMGISRTFQNLQ--LFQAMNVFENIysglihkyNDSLFSVFSKSK-MNFDKEAREKVLEVAEMFDIKNR---LTS 143
Cdd:COG4170 83 rrkIIGREIAMIFQEPSscLDPSAKIGDQL--------IEAIPSWTFKGKwWQRFKWRKKRAIELLHRVGIKDHkdiMNS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 144 YPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNF 222
Cdd:COG4170 155 YPHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlQGTSILLISHDLESISQWADTITVLYC 234
|
250
....*....|....*
gi 1341787947 223 GKKIAEGTPEDIANN 237
Cdd:COG4170 235 GQTVESGPTEQILKS 249
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
1-226 |
7.97e-22 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 93.70 E-value: 7.97e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRiVNPH---KGDILFKGESLLKLDTHDIIYMG 77
Cdd:NF040905 1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG-VYPHgsyEGEILFDGEVCRFKDIRDSEALG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQLFQAMNVFENIYSGlihkyND-SLFSVFSKSKMNfdKEAREKVLEVAemfdiknrLTSYP----SQLTYGM 152
Cdd:NF040905 80 IVIIHQELALIPYLSIAENIFLG-----NErAKRGVIDWNETN--RRARELLAKVG--------LDESPdtlvTDIGVGK 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKI 226
Cdd:NF040905 145 QQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGRTI 218
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
2-233 |
8.91e-22 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 90.37 E-value: 8.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG--LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI-IYMGI 78
Cdd:cd03251 1 VEFKNVTFRYPGdgPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLrRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 srTFQNLQLFQAmNVFENIYSGLihkyndslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYP-----------SQ 147
Cdd:cd03251 81 --VSQDVFLFND-TVAENIAYGR-------------------PGATREEVEEAARAANAHEFIMELPegydtvigergVK 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyYETEEI--KSIIQMVnkRGKTILLVEHDMNVVMNvSDLVTVMNFGKK 225
Cdd:cd03251 139 LSGGQRQRIAIARALLKDPPILILDEATSALD-TESERLvqAALERLM--KNRTTFVIAHRLSTIEN-ADRIVVLEDGKI 214
|
....*...
gi 1341787947 226 IAEGTPED 233
Cdd:cd03251 215 VERGTHEE 222
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1-234 |
1.25e-21 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 91.71 E-value: 1.25e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKT-TLF--------NTITrivnphKGDILFKGESLLK 67
Cdd:PRK09473 12 LLDVKDLRVTFstpdGDVTAVNDLNFSLRAGETLGIVGESGSGKSqTAFalmgllaaNGRI------GGSATFNGREILN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 68 LDTHDIIYMgisRTFQNLQLFQAMNVFENIYSglihKYNDSLFSVFSKSKMNFDKEARE---KVLEVAEMFDIKNRLTSY 144
Cdd:PRK09473 86 LPEKELNKL---RAEQISMIFQDPMTSLNPYM----RVGEQLMEVLMLHKGMSKAEAFEesvRMLDAVKMPEARKRMKMY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 145 PSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKT-ILLVEHDMNVVMNVSDLVTVMNFG 223
Cdd:PRK09473 159 PHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAG 238
|
250
....*....|.
gi 1341787947 224 KKIAEGTPEDI 234
Cdd:PRK09473 239 RTMEYGNARDV 249
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-224 |
1.62e-21 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 89.16 E-value: 1.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYM--G 77
Cdd:PRK10908 1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLrrQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQLFQAMNVFENIYSGLIhkyndslfsVFSKSkmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK10908 81 IGMIFQDHHLLMDRTVYDNVAIPLI---------IAGAS----GDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVG 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:PRK10908 148 IARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGH 214
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-207 |
1.73e-21 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 89.42 E-value: 1.73e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGG----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLD------- 69
Cdd:COG4181 8 IIELRGLTKTVGTgageLTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDedararl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 70 --THdiiyMGIsrTFQNLQLFQAMNVFENI-----YSGlihkyndslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLT 142
Cdd:COG4181 88 raRH----VGF--VFQSFQLLPTLTALENVmlpleLAG--------------------RRDARARARALLERVGLGHRLD 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 143 SYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLnyyETEEIKSIIQM---VNK-RGKTILLVEHDM 207
Cdd:COG4181 142 HYPAQLSGGEQQRVALARAFATEPAILFADEPTGNL---DAATGEQIIDLlfeLNReRGTTLVLVTHDP 207
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-237 |
1.74e-21 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 90.10 E-value: 1.74e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPH-----KGDILFKGESLLKLDTH-DIIY 75
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELEsevrvEGRVEFFNQNIYERRVNlNRLR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGISRTFQNLQLFqAMNVFENIYSGLIhkyndslfSVFSKSKMNFDkEAREKVLEVAEMFD-IKNRLTSYPSQLTYGMLK 154
Cdd:PRK14258 88 RQVSMVHPKPNLF-PMSVYDNVAYGVK--------IVGWRPKLEID-DIVESALKDADLWDeIKHKIHKSALDLSGGQQQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGK-TILLVEHDMNVVMNVSDLVTVMN-----FGKKIAE 228
Cdd:PRK14258 158 RLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSElTMVIVSHNLHQVSRLSDFTAFFKgnenrIGQLVEF 237
|
....*....
gi 1341787947 229 GTPEDIANN 237
Cdd:PRK14258 238 GLTKKIFNS 246
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1-226 |
2.18e-21 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 92.46 E-value: 2.18e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF--GGL--KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITR------IVNPHkGDILFKGESLLKLDt 70
Cdd:PRK15134 5 LLAIENLSVAFrqQQTvrTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRllpsppVVYPS-GDIRFHGESLLHAS- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 71 hdiiymgiSRTFQNLQLFQAMNVFENIYSGL--IHKYNDSLFSVFSKSKMNFDKEAREKVLEVAEMFDIKN---RLTSYP 145
Cdd:PRK15134 83 --------EQTLRGVRGNKIAMIFQEPMVSLnpLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQaakRLTDYP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 146 SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:PRK15134 155 HQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKLADRVAVMQNGR 234
|
..
gi 1341787947 225 KI 226
Cdd:PRK15134 235 CV 236
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
2-206 |
2.84e-21 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 92.04 E-value: 2.84e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDtHDIIYMGISR 80
Cdd:TIGR02868 335 LELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLD-QDEVRRRVSV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFqAMNVFENIYSGLIHKYNDSLFSVFSKSKMNFDKEAREKVLEvaemfdikNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:TIGR02868 414 CAQDAHLF-DTTVRENLRLARPDATDEELWAALERVGLADWLRALPDGLD--------TVLGEGGARLSGGERQRLALAR 484
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1341787947 161 AVISDPDLLLLDEPAAGLNyYETEEikSIIQMVNK--RGKTILLVEHD 206
Cdd:TIGR02868 485 ALLADAPILLLDEPTEHLD-AETAD--ELLEDLLAalSGRTVVLITHH 529
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
1-234 |
3.89e-21 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 90.70 E-value: 3.89e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVkNVTVTFGGLkavnDFSITI---SQGkIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLklDTHDIIYM- 76
Cdd:PRK11144 1 MLEL-NFKQQLGDL----CLTVNLtlpAQG-ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLF--DAEKGICLp 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 ----GISRTFQNLQLFQAMNVFENIYSGLIHKyndslfsvfskSKMNFDKearekvleVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:PRK11144 73 pekrRIGYVFQDARLFPHYKVRGNLRYGMAKS-----------MVAQFDK--------IVALLGIEPLLDRYPGSLSGGE 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKT-ILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTP 231
Cdd:PRK11144 134 KQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIpILYVSHSLDEILRLADRVVVLEQGKVKAFGPL 213
|
...
gi 1341787947 232 EDI 234
Cdd:PRK11144 214 EEV 216
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
6-234 |
4.27e-21 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 89.38 E-value: 4.27e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 6 NVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNP-----HKGDILFKGESLLklDTHDIIYMG--I 78
Cdd:PRK14271 26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSIF--NYRDVLEFRrrV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNLQLFqAMNVFENIYSGL-IHKYndslfsvfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK14271 104 GMLFQRPNPF-PMSIMDNVLAGVrAHKL---------VPRKEFRGVAQARLTEVGLWDAVKDRLSDSPFRLSGGQQQLLC 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRgKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK14271 174 LARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQL 249
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-234 |
4.52e-21 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 91.06 E-value: 4.52e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgISR 80
Cdd:PRK09536 3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRR-VAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGLI-HKyndSLFSVFSKSkmnfDKEAREKVLEVAEMFDIKNR-LTSypsqLTYGMLKRVEM 158
Cdd:PRK09536 82 VPQDTSLSFEFDVRQVVEMGRTpHR---SRFDTWTET----DRAAVERAMERTGVAQFADRpVTS----LSGGERQRVLL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK09536 151 ARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADV 226
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
1-241 |
5.76e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 89.52 E-value: 5.76e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGG-----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKG-ESLLKLDTHDII 74
Cdd:PRK13631 21 ILRVKNLYCVFDEkqeneLVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDiYIGDKKNNHELI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMGISRTFQNLQLFQAM--NVFE----NIYSGLIHKynDSLFS--VFSKSKmnfdKEAREKVLEVAEMFDIKNR-LTSYP 145
Cdd:PRK13631 101 TNPYSKKIKNFKELRRRvsMVFQfpeyQLFKDTIEK--DIMFGpvALGVKK----SEAKKLAKFYLNKMGLDDSyLERSP 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 146 SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKK 225
Cdd:PRK13631 175 FGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKI 254
|
250
....*....|....*.
gi 1341787947 226 IAEGTPEDIANNEEVV 241
Cdd:PRK13631 255 LKTGTPYEIFTDQHII 270
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-206 |
7.69e-21 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 90.89 E-value: 7.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 4 VKNVTVTFGGLKAVNDFSITISQG-KIhALIGPNGAGKTTLFNTITRIVNPHKGDILF-KGESLLKLDthdiiymgisrt 81
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGdRI-GLVGRNGAGKSTLLKILAGELEPDSGEVSIpKGLRIGYLP------------ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fQNLQLFQAMNVFENIYSG------LIHKYNDSLfsvfskSKMNFDKEAREKVLEVAEMFDIKN---------------R 140
Cdd:COG0488 68 -QEPPLDDDLTVLDTVLDGdaelraLEAELEELE------AKLAEPDEDLERLAELQEEFEALGgweaearaeeilsglG 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 141 LTSYP-----SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLnyyeteEIKSII---QMVNKRGKTILLVEHD 206
Cdd:COG0488 141 FPEEDldrpvSELSGGWRRRVALARALLSEPDLLLLDEPTNHL------DLESIEwleEFLKNYPGTVLVVSHD 208
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
2-234 |
9.08e-21 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 90.51 E-value: 9.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF-----------GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVnPHKGDILFKGESLLKLDT 70
Cdd:COG4172 276 LEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSR 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 71 HDIiymgisRTF-QNLQL-FQ--------AMNVFENIYSGL-IHkyndslfsvfsksKMNFDKEAREKvlEVAEMF---- 135
Cdd:COG4172 355 RAL------RPLrRRMQVvFQdpfgslspRMTVGQIIAEGLrVH-------------GPGLSAAERRA--RVAEALeevg 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 136 ---DIKNRltsYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyyeteeiKSI-IQMVN-------KRGKTILLVE 204
Cdd:COG4172 414 ldpAARHR---YPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALD-------VSVqAQILDllrdlqrEHGLAYLFIS 483
|
250 260 270
....*....|....*....|....*....|
gi 1341787947 205 HDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:COG4172 484 HDLAVVRALAHRVMVMKDGKVVEQGPTEQV 513
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-221 |
1.09e-20 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 87.92 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTL---FNTITRIVNPHK--GDILFKGESLLKLDTHDI-IY 75
Cdd:PRK14243 11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTIlrcFNRLNDLIPGFRveGKVTFHGKNLYAPDVDPVeVR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGISRTFQNLQLFQAmNVFENI-YSGLIHKYndslfsvfsksKMNFDkEAREKVLEVAEMFD-IKNRLTSYPSQLTYGML 153
Cdd:PRK14243 91 RRIGMVFQKPNPFPK-SIYDNIaYGARINGY-----------KGDMD-ELVERSLRQAALWDeVKDKLKQSGLSLSGGQQ 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNVSDLVTVMN 221
Cdd:PRK14243 158 QRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHEL-KEQYTIIIVTHNMQQAARVSDMTAFFN 224
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
15-244 |
2.00e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 87.87 E-value: 2.00e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKG-----DILFKGESLLKLDTHDIIYMGISRTFQNLQLFQ 89
Cdd:PRK13643 20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGkvtvgDIVVSSTSKQKEIKPVRKKVGVVFQFPESQLFE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 90 AmNVFENIysglihkyndslfsVFSKSKMNFDKEAREKVL-EVAEMFDIKNRL-TSYPSQLTYGMLKRVEMARAVISDPD 167
Cdd:PRK13643 100 E-TVLKDV--------------AFGPQNFGIPKEKAEKIAaEKLEMVGLADEFwEKSPFELSGGQMRRVAIAGILAMEPE 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 168 LLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEVVKVY 244
Cdd:PRK13643 165 VLVLDEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEVDFLKAH 241
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
2-234 |
2.30e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 87.49 E-value: 2.30e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVT------FGGlKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDII- 74
Cdd:PRK13649 3 INLQNVSYTyqagtpFEG-RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 ----YMGISRTFQNLQLFQAmNVFENIYSGLIHkyndslfsvFSKSKMNFDKEAREKVLEVA---EMFDiKNrltsyPSQ 147
Cdd:PRK13649 82 qirkKVGLVFQFPESQLFEE-TVLKDVAFGPQN---------FGVSQEEAEALAREKLALVGiseSLFE-KN-----PFE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIA 227
Cdd:PRK13649 146 LSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVL 225
|
....*..
gi 1341787947 228 EGTPEDI 234
Cdd:PRK13649 226 SGKPKDI 232
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
6-241 |
3.39e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 86.99 E-value: 3.39e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 6 NVTVTFGG-----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFkGESLLKLDTHDIIY----- 75
Cdd:PRK13645 11 NVSYTYAKktpfeFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIV-GDYAIPANLKKIKEvkrlr 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 --MGISRTFQNLQLFQAmNVFENIYSGLIHKYNDSlfsvfskskmnfdKEAREKVLEVAEMFDI-KNRLTSYPSQLTYGM 152
Cdd:PRK13645 90 keIGLVFQFPEYQLFQE-TIEKDIAFGPVNLGENK-------------QEAYKKVPELLKLVQLpEDYVKRSPFELSGGQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTP 231
Cdd:PRK13645 156 KRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKeYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSP 235
|
250
....*....|
gi 1341787947 232 EDIANNEEVV 241
Cdd:PRK13645 236 FEIFSNQELL 245
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-230 |
4.63e-20 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 85.84 E-value: 4.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESL---LKLDTHDIIYM-- 76
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsKTPSDKAIRELrr 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQNLQLFQAMNVFENiysgLIhkynDSLFSVFSKSKmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRV 156
Cdd:PRK11124 83 NVGMVFQQYNLWPHLTVQQN----LI----EAPCRVLGLSK----DQALARAEKLLERLRLKPYADRFPLHLSGGQQQRV 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGT 230
Cdd:PRK11124 151 AIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGD 224
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-244 |
4.80e-20 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 85.98 E-value: 4.80e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDT---------- 70
Cdd:PRK13548 2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPaelarrravl 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 71 ------------HDIIYMGISrtfqnlqlfqamnvfenIYSGLIHKyndslfsvfskskmnfDKEAREKVLEVAEMFDIK 138
Cdd:PRK13548 82 pqhsslsfpftvEEVVAMGRA-----------------PHGLSRAE----------------DDALVAAALAQVDLAHLA 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 139 NRltSYPsQLTYGMLKRVEMARA------VISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVM 211
Cdd:PRK13548 129 GR--DYP-QLSGGEQQRVQLARVlaqlwePDGPPRWLLLDEPTSALDLAHQHHVLRLArQLAHERGLAVIVVLHDLNLAA 205
|
250 260 270
....*....|....*....|....*....|...
gi 1341787947 212 NVSDLVTVMNFGKKIAEGTPEDIANNEEVVKVY 244
Cdd:PRK13548 206 RYADRIVLLHQGRLVADGTPAEVLTPETLRRVY 238
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
15-241 |
6.20e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 86.37 E-value: 6.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKG-----DILFKGESLLKLDTHDIIYMGISRTFQNLQLFQ 89
Cdd:PRK13646 21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGtvtvdDITITHKTKDKYIRPVRKRIGMVFQFPESQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 90 AmNVFENIYSGLihkyndslfsvfSKSKMNFDkEAREKVLEVAEMFDI-KNRLTSYPSQLTYGMLKRVEMARAVISDPDL 168
Cdd:PRK13646 101 D-TVEREIIFGP------------KNFKMNLD-EVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAIVSILAMNPDI 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 169 LLLDEPAAGLNYYETEEIKSIIQMVN-KRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEVV 241
Cdd:PRK13646 167 IVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKKKL 240
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
2-233 |
7.52e-20 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 88.30 E-value: 7.52e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAV-NDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiYMG-IS 79
Cdd:COG1132 340 IEFENVSFSYPGDRPVlKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLES--LRRqIG 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLFqAMNVFENIysglihKYndslfsvfskskmnFDKEA-REKVLEVAEMFDIKNRLTSYPSQL-TY-----GM 152
Cdd:COG1132 418 VVPQDTFLF-SGTIRENI------RY--------------GRPDAtDEEVEEAAKAAQAHEFIEALPDGYdTVvgergVN 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 L-----KRVEMARAVISDPDLLLLDEPAAGLNyYETEEIksIIQMVNK--RGKTILLVEHDMNVVMNVsDLVTVMNFGKK 225
Cdd:COG1132 477 LsggqrQRIAIARALLKDPPILILDEATSALD-TETEAL--IQEALERlmKGRTTIVIAHRLSTIRNA-DRILVLDDGRI 552
|
....*...
gi 1341787947 226 IAEGTPED 233
Cdd:COG1132 553 VEQGTHEE 560
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
15-246 |
7.71e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 86.23 E-value: 7.71e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILF---------KGESLLKLDTHdiiyMGISRTFQNL 85
Cdd:PRK13634 21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitagkKNKKLKPLRKK----VGIVFQFPEH 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 86 QLFQAmNVFENIYSGlihkyndslfsvfsksKMNF---DKEAREKVLEVAEMFDIKNR-LTSYPSQLTYGMLKRVEMARA 161
Cdd:PRK13634 97 QLFEE-TVEKDICFG----------------PMNFgvsEEDAKQKAREMIELVGLPEElLARSPFELSGGQMRRVAIAGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI-ANNEE 239
Cdd:PRK13634 160 LAMEPEVLVLDEPTAGLDPKGRKEMMEMFyKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIfADPDE 239
|
....*..
gi 1341787947 240 VVKVYLG 246
Cdd:PRK13634 240 LEAIGLD 246
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
1-237 |
9.42e-20 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 86.30 E-value: 9.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFG-------------GLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLK 67
Cdd:PRK15079 8 LLEVADLKVHFDikdgkqwfwqppkTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 68 LDTHDI--IYMGISRTFQN--LQLFQAMNVFENIYSGLiHKYNDSLfsvfskSKMNFDKEAREKVLEVAEMFDIKNRlts 143
Cdd:PRK15079 88 MKDDEWraVRSDIQMIFQDplASLNPRMTIGEIIAEPL-RTYHPKL------SRQEVKDRVKAMMLKVGLLPNLINR--- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 144 YPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNF 222
Cdd:PRK15079 158 YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHISDRVLVMYL 237
|
250
....*....|....*
gi 1341787947 223 GKKIAEGTPEDIANN 237
Cdd:PRK15079 238 GHAVELGTYDEVYHN 252
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
2-244 |
1.84e-19 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 84.65 E-value: 1.84e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgISRT 81
Cdd:PRK10253 8 LRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARR-IGLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGlihKY-NDSLFSVFSKSkmnfDKEAREKVLEVAEMFDIKNRLTsypSQLTYGMLKRVEMAR 160
Cdd:PRK10253 87 AQNATTPGDITVQELVARG---RYpHQPLFTRWRKE----DEEAVTKAMQATGITHLADQSV---DTLSGGQRQRAWIAM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNK-RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEE 239
Cdd:PRK10253 157 VLAQETAIMLLDEPTTWLDISHQIDLLELLSELNReKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAEL 236
|
....*
gi 1341787947 240 VVKVY 244
Cdd:PRK10253 237 IERIY 241
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
2-224 |
1.85e-19 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 84.34 E-value: 1.85e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfKGESLLKLDTHDIIYMgisrt 81
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELL-AGTAPLAEAREDTRLM----- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYSGLIHKYndslfsvfskskmnfdkeaREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:PRK11247 87 FQDARLLPWKKVIDNVGLGLKGQW-------------------RDAALQALAAVGLADRANEWPAALSGGQKQRVALARA 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMV-NKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:PRK11247 148 LIHRPGLLLLDEPLGALDALTRIEMQDLIESLwQQHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
2-224 |
2.93e-19 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 81.88 E-value: 2.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKA--VNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDthdiiyMGIS 79
Cdd:cd03246 1 LEVENVSFRYPGAEPpvLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWD------PNEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTF-----QNLQLFqAMNVFENIYSGlihkyndslfsvfskskmnfdkearekvlevaemfdiknrltsypsqltyGMLK 154
Cdd:cd03246 75 GDHvgylpQDDELF-SGSIAENILSG--------------------------------------------------GQRQ 103
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVsDLVTVMNFGK 224
Cdd:cd03246 104 RLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAGATRIVIAHRPETLASA-DRILVLEDGR 172
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
14-229 |
2.95e-19 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 83.09 E-value: 2.95e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 14 LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHK---GDILFKGESLLKLDTHDIiymgISRTFQNLQLFQA 90
Cdd:cd03234 20 ARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPRKPDQFQKC----VAYVRQDDILLPG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 91 MNVFENIYsglihkyndslFSVFSKSKMNFDKEAREKVLEVAEMFDIKNRLT--SYPSQLTYGMLKRVEMARAVISDPDL 168
Cdd:cd03234 96 LTVRETLT-----------YTAILRLPRKSSDAIRKKRVEDVLLRDLALTRIggNLVKGISGGERRRVSIAVQLLWDPKV 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 169 LLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEH----DMnvvMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03234 165 LILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHqprsDL---FRLFDRILLLSSGEIVYSG 226
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
2-240 |
3.01e-19 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 86.23 E-value: 3.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVT-FGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGIS- 79
Cdd:COG3845 258 LEVENLSVRdDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERRRLGVAy 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 ----RtfQNLQLFQAMNVFENIysgLIHKYNDSLFSvfSKSKMNFdKEAREKVLEVAEMFDIKNRLTSYP-SQLTYGMLK 154
Cdd:COG3845 338 ipedR--LGRGLVPDMSVAENL---ILGRYRRPPFS--RGGFLDR-KAIRAFAEELIEEFDVRTPGPDTPaRSLSGGNQQ 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNkRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:COG3845 410 KVILARELSRDPKLLIAAQPTRGLDVGAIEFIhQRLLELRD-AGAAVLLISEDLDEILALSDRIAVMYEGRIVGEVPAAE 488
|
....*..
gi 1341787947 234 iANNEEV 240
Cdd:COG3845 489 -ATREEI 494
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
19-209 |
3.57e-19 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 83.33 E-value: 3.57e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTH---DIIYMGISRTFQNLQLFQAMNVFE 95
Cdd:PRK11629 27 NVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAakaELRNQKLGFIYQFHHLLPDFTALE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 96 NIYSGLIhkyndslfsvFSKSKmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPA 175
Cdd:PRK11629 107 NVAMPLL----------IGKKK---PAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPT 173
|
170 180 190
....*....|....*....|....*....|....*
gi 1341787947 176 AGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNV 209
Cdd:PRK11629 174 GNLDARNADSIFQLLGELNRLqGTAFLVVTHDLQL 208
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-234 |
4.07e-19 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 84.89 E-value: 4.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTL------FNTITrivnphKGDILFKGESLLKLDTHDi 73
Cdd:PRK11650 3 GLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLlrmvagLERIT------SGEIWIGGRVVNELEPAD- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 iyMGISRTFQNLQLFQAMNVFENIYSGL-IHKyndslfsvFSKSkmnfdkEAREKVLEVAEMFDIKNRLTSYPSQLTYGM 152
Cdd:PRK11650 76 --RDIAMVFQNYALYPHMSVRENMAYGLkIRG--------MPKA------EIEERVAEAARILELEPLLDRKPRELSGGQ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLnyyeteEIKSIIQM------VNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKk 225
Cdd:PRK11650 140 RQRVAMGRAIVREPAVFLFDEPLSNL------DAKLRVQMrleiqrLHRRlKTTSLYVTHDQVEAMTLADRVVVMNGGV- 212
|
250
....*....|.
gi 1341787947 226 iAE--GTPEDI 234
Cdd:PRK11650 213 -AEqiGTPVEV 222
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-205 |
5.61e-19 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 82.71 E-value: 5.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAvnDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllkldTHDIIYMG--- 77
Cdd:PRK10771 1 MLKLTDITWLYHHLPM--RFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQ------DHTTTPPSrrp 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQLFQAMNVFENIYSGLihkyNDSLfsvfsksKMNFDKeaREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK10771 73 VSMLFQENNLFSHLTVAQNIGLGL----NPGL-------KLNAAQ--REKLHAIARQMGIEDLLARLPGQLSGGQRQRVA 139
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMV-NKRGKTILLVEH 205
Cdd:PRK10771 140 LARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVcQERQLTLLMVSH 188
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1-239 |
6.43e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 83.26 E-value: 6.43e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKA--VNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDI-IYMG 77
Cdd:PRK13648 7 IIVFKNVSFQYQSDASftLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLrKHIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 IsrTFQNLqlfqamnvfENIYSGLIHKYnDSLFSVfsKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK13648 87 I--VFQNP---------DNQFVGSIVKY-DVAFGL--ENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVN-KRGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDIAN 236
Cdd:PRK13648 153 IAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKsEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFD 231
|
...
gi 1341787947 237 NEE 239
Cdd:PRK13648 232 HAE 234
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-251 |
8.78e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 83.60 E-value: 8.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----------GGLK-----------AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDIL 59
Cdd:COG4586 1 IIEVENLSKTYrvyekepglkGALKglfrreyreveAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 60 FKG-------ESLLKldthDI-IYMGisrtfQNLQLFQAMNVFEniySGLIHK--YNDSlfsvfskskmnfDKEAREKVL 129
Cdd:COG4586 81 VLGyvpfkrrKEFAR----RIgVVFG-----QRSQLWWDLPAID---SFRLLKaiYRIP------------DAEYKKRLD 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 130 EVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKS-IIQMVNKRGKTILLVEHDMN 208
Cdd:COG4586 137 ELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREfLKEYNRERGTTILLTSHDMD 216
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1341787947 209 VVMNVSDLVTVMNFGKKIAEGTPEDIAN---NEEVVKVYLGEDENA 251
Cdd:COG4586 217 DIEALCDRVIVIDHGRIIYDGSLEELKErfgPYKTIVLELAEPVPP 262
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
2-224 |
1.03e-18 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 81.75 E-value: 1.03e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVN---DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDtHDIIYMGI 78
Cdd:cd03248 12 VKFQNVTFAYPTRPDTLvlqDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYE-HKYLHSKV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNLQLFqAMNVFENIYSGLIHKYNDSLFSVFSK-------SKM--NFDKEAREKvlevaemfdiknrltsyPSQLT 149
Cdd:cd03248 91 SLVGQEPVLF-ARSLQDNIAYGLQSCSFECVKEAAQKahahsfiSELasGYDTEVGEK-----------------GSQLS 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRgKTILLVEHDMNVVMNvSDLVTVMNFGK 224
Cdd:cd03248 153 GGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPER-RTVLVIAHRLSTVER-ADQILVLDGGR 225
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
1-234 |
1.34e-18 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 83.31 E-value: 1.34e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPH---KGD-ILFKGESLLKL---D 69
Cdd:PRK15093 3 LLDIRNLTIEFktsdGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNwrvTADrMRFDDIDLLRLsprE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 70 THDIIYMGISRTFQNLQlfQAMNVFENIYSGLIHKYNDSLFSVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLT 149
Cdd:PRK15093 83 RRKLVGHNVSMIFQEPQ--SCLDPSERVGRQLMQNIPGWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAE 228
Cdd:PRK15093 161 EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNnNTTILLISHDLQMLSQWADKINVLYCGQTVET 240
|
....*.
gi 1341787947 229 GTPEDI 234
Cdd:PRK15093 241 APSKEL 246
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
20-244 |
1.37e-18 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 81.90 E-value: 1.37e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 20 FSITISQGKIHALIGPNGAGKTTLFNTITRIVnPHKGDILFKGESLLKLDTHDiiyMGISRTF---QNLQLFqAMNVFEn 96
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEAWSAAE---LARHRAYlsqQQTPPF-AMPVFQ- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 97 iYSGLihkyndslfSVFSKSkmnfDKEAREKVL-EVAEMFDIKNRLTSYPSQLTYGMLKRVEMArAVI------SDPD-- 167
Cdd:PRK03695 89 -YLTL---------HQPDKT----RTEAVASALnEVAEALGLDDKLGRSVNQLSGGEWQRVRLA-AVVlqvwpdINPAgq 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 168 LLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNEEVVKVY 244
Cdd:PRK03695 154 LLLLDEPMNSLDVAQQAALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQVF 230
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-230 |
1.48e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 84.49 E-value: 1.48e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF--GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfkgesllkLDTHDIiymgis 79
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEIL--------LNGQPI------ 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLFQAMNVFeniySGLIHKYNDSLfsvfsksKMNF----DKEAREKVLEVAEMFDIKNRLTSYPS--------- 146
Cdd:PRK11160 405 ADYSEAALRQAISVV----SQRVHLFSATL-------RDNLllaaPNASDEALIEVLQQVGLEKLLEDDKGlnawlgegg 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 147 -QLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyYETEeiKSIIQMVNK--RGKTILLVEHDMNvVMNVSDLVTVMNFG 223
Cdd:PRK11160 474 rQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLD-AETE--RQILELLAEhaQNKTVLMITHRLT-GLEQFDRICVMDNG 549
|
....*..
gi 1341787947 224 KKIAEGT 230
Cdd:PRK11160 550 QIIEQGT 556
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-244 |
2.36e-18 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 81.31 E-value: 2.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDIlfKGESLLKldthdiiymgISR 80
Cdd:PRK09544 4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI--KRNGKLR----------IGY 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVfeniysglihkyndsLFSVFSKSKMNFDKEAREKVLEVAEmfdiKNRLTSYPSQ-LTYGMLKRVEMA 159
Cdd:PRK09544 72 VPQKLYLDTTLPL---------------TVNRFLRLRPGTKKEDILPALKRVQ----AGHLIDAPMQkLSGGETQRVLLA 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNVSDLVTVMNfGKKIAEGTPEDIANNE 238
Cdd:PRK09544 133 RALLNRPQLLVLDEPTQGVDVNGQVALYDLIdQLRRELDCAVLMVSHDLHLVMAKTDEVLCLN-HHICCSGTPEVVSLHP 211
|
....*.
gi 1341787947 239 EVVKVY 244
Cdd:PRK09544 212 EFISMF 217
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
2-229 |
2.47e-18 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 80.71 E-value: 2.47e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG--LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiYMGIS 79
Cdd:cd03245 3 IEFRNVSFSYPNqeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADL-RRNIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLFQAmNVFENIysglihkyndSLFSVFSKSkmnfdkearEKVLEVAEMFDIKNRLTSYP-----------SQL 148
Cdd:cd03245 82 YVPQDVTLFYG-TLRDNI----------TLGAPLADD---------ERILRAAELAGVTDFVNKHPngldlqigergRGL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 149 TYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMnVVMNVSDLVTVMNFGKKIAE 228
Cdd:cd03245 142 SGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQL-LGDKTLIIITHRP-SLLDLVDRIIVMDSGRIVAD 219
|
.
gi 1341787947 229 G 229
Cdd:cd03245 220 G 220
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
14-237 |
2.87e-18 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 82.32 E-value: 2.87e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 14 LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHdiiymGISRTFQNLQLfqamnV 93
Cdd:PRK11308 28 VKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPE-----AQKLLRQKIQI-----V 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 94 FENIYSGL--IHKYNDSLFSVFsksKMNFD---KEAREKVLEVAEMFDIK----NRltsYPSQLTYGMLKRVEMARAVIS 164
Cdd:PRK11308 98 FQNPYGSLnpRKKVGQILEEPL---LINTSlsaAERREKALAMMAKVGLRpehyDR---YPHMFSGGQRQRIAIARALML 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 165 DPDLLLLDEPAAGLNYyeteeikSI-IQMVN-------KRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIAN 236
Cdd:PRK11308 172 DPDVVVADEPVSALDV-------SVqAQVLNlmmdlqqELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFN 244
|
.
gi 1341787947 237 N 237
Cdd:PRK11308 245 N 245
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
2-242 |
5.70e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 81.00 E-value: 5.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLK--AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGD---ILFKGESLLKLDTHDII-Y 75
Cdd:PRK13640 6 VEFKHVSFTYPDSKkpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTAKTVWDIReK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGIsrTFQNL-QLFQAMNVFENIYSGLIHKyndslfsVFSKSKMnfdKEAREKVLEVAEMFDIKNrltSYPSQLTYGMLK 154
Cdd:PRK13640 86 VGI--VFQNPdNQFVGATVGDDVAFGLENR-------AVPRPEM---IKIVRDVLADVGMLDYID---SEPANLSGGQKQ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSIIQMVNKRGKTILLVEHDMNVVmNVSDLVTVMNFGKKIAEGTPED 233
Cdd:PRK13640 151 RVAIAGILAVEPKIIILDESTSMLDPAGKEQIlKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVE 229
|
....*....
gi 1341787947 234 IANNEEVVK 242
Cdd:PRK13640 230 IFSKVEMLK 238
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-245 |
5.86e-18 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 82.54 E-value: 5.86e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTI--TRIVNPHKGDILFK------------------ 61
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLrgMDQYEPTSGRIIYHvalcekcgyverpskvge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 62 -----GESLLKLD----------THDI---IYMGISRTFQnlqLFQAMNVFENIYSGLihkyNDSLFSvfskskmnfDKE 123
Cdd:TIGR03269 81 pcpvcGGTLEPEEvdfwnlsdklRRRIrkrIAIMLQRTFA---LYGDDTVLDNVLEAL----EEIGYE---------GKE 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 124 AREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyYETEEI--KSIIQMVNKRGKTIL 201
Cdd:TIGR03269 145 AVGRAVDLIEMVQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLD-PQTAKLvhNALEEAVKASGISMV 223
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1341787947 202 LVEHDMNVVMNVSDLVTVMNFGKKIAEGTPediannEEVVKVYL 245
Cdd:TIGR03269 224 LTSHWPEVIEDLSDKAIWLENGEIKEEGTP------DEVVAVFM 261
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-251 |
6.01e-18 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 82.37 E-value: 6.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTfgglKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGI-- 78
Cdd:COG1129 256 VLEVEGLSVG----GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDAIRAGIay 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 ---SRtfQNLQLFQAMNVFENIYSGLIHKYndSLFSVFSKSKMnfdkeaREKVLEVAEMFDIKnrlTSYPSQLTyGML-- 153
Cdd:COG1129 332 vpeDR--KGEGLVLDLSIRENITLASLDRL--SRGGLLDRRRE------RALAEEYIKRLRIK---TPSPEQPV-GNLsg 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 ---KRVEMARAVISDPDLLLLDEPaaglnyyeT--------EEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNF 222
Cdd:COG1129 398 gnqQKVVLAKWLATDPKVLILDEP--------TrgidvgakAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMRE 469
|
250 260
....*....|....*....|....*....
gi 1341787947 223 GKKIAEGTPEDiANNEEVVKVYLGEDENA 251
Cdd:COG1129 470 GRIVGELDREE-ATEEAIMAAATGGAAAA 497
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
2-246 |
9.49e-18 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 80.06 E-value: 9.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLK--AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgIS 79
Cdd:PRK13635 6 IRVEHISFRYPDAAtyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRRQ-VG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNL-QLFQAMNVFENIYSGLihkYNDSLfsvfSKSKMnfdkeaREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEM 158
Cdd:PRK13635 85 MVFQNPdNQFVGATVQDDVAFGL---ENIGV----PREEM------VERVDQALRQVGMEDFLNREPHRLSGGQKQRVAI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDI-AN 236
Cdd:PRK13635 152 AGVLALQPDIIILDEATSMLDPRGRREVLETVrQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIfKS 230
|
250
....*....|
gi 1341787947 237 NEEVVKVYLG 246
Cdd:PRK13635 231 GHMLQEIGLD 240
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-234 |
1.07e-17 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 81.59 E-value: 1.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISR 80
Cdd:PRK10762 4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSQEAGIGI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIYSGlihKYNDSLFSVFSKSKMNFDKEAREKVLEVAemFDIKNRLtsypSQLTYGMLKRVEMAR 160
Cdd:PRK10762 84 IHQELNLIPQLTIAENIFLG---REFVNRFGRIDWKKMYAEADKLLARLNLR--FSSDKLV----GELSIGEQQMVEIAK 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK10762 155 VLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQFIAEREVADL 228
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
5-231 |
1.22e-17 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 80.84 E-value: 1.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 5 KNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiiyMGISRTFQN 84
Cdd:PRK11000 7 RNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAE---RGVGMVFQS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 85 LQLFQAMNVFENIYSGLihkyndslfsVFSKSKMNfdkEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVIS 164
Cdd:PRK11000 84 YALYPHLSVAENMSFGL----------KLAGAKKE---EINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 165 DPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTP 231
Cdd:PRK11000 151 EPSVFLLDEPLSNLDAALRVQMRIEISRLHKRlGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP 218
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-206 |
1.24e-17 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 76.72 E-value: 1.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDIlfkgesllklDTHDIIYMGisrt 81
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV----------TWGSTVKIG---- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fqnlqlfqamnvfeniysglihkyndslfsvfskskmnfdkearekvlevaemfdiknrltsYPSQLTYGMLKRVEMARA 161
Cdd:cd03221 67 --------------------------------------------------------------YFEQLSGGEKMRLALAKL 84
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1341787947 162 VISDPDLLLLDEPaagLNYYETEEIKSIIQMVNKRGKTILLVEHD 206
Cdd:cd03221 85 LLENPNLLLLDEP---TNHLDLESIEALEEALKEYPGTVILVSHD 126
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
17-234 |
1.40e-17 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 79.32 E-value: 1.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 17 VNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHK------GDILFKGESLLKLDTHDIiYMGISRTFQNLQLFQA 90
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDskikvdGKVLYFGKDIFQIDAIKL-RKEVGMVFQQPNPFPH 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 91 MNVFENIYSglihkyndSLFSVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLL 170
Cdd:PRK14246 105 LSIYDNIAY--------PLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 171 LDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK14246 177 MDEPTSMIDIVNSQAIEKLITEL-KNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEI 239
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
9-232 |
1.57e-17 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 78.81 E-value: 1.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 9 VTFG---GLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgISRTFQNL 85
Cdd:cd03253 6 VTFAydpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRA-IGVVPQDT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 86 QLFQAmNVFENIysglihKYNDslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQ-----------LTYGMLK 154
Cdd:cd03253 85 VLFND-TIGYNI------RYGR-------------PDATDEEVIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQ 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKrGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPE 232
Cdd:cd03253 145 RVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSK-GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHE 220
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
4-231 |
1.80e-17 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 81.60 E-value: 1.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 4 VKNVTVTF--GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESllkLDTH-DIIYMGISR 80
Cdd:TIGR01257 931 VKNLVKIFepSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKD---IETNlDAVRQSLGM 1007
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNVFENIysglihkyndsLFsvFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMAR 160
Cdd:TIGR01257 1008 CPQHNILFHHLTVAEHI-----------LF--YAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAI 1074
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIqMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTP 231
Cdd:TIGR01257 1075 AFVGDAKVVVLDEPTSGVDPYSRRSIWDLL-LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
4-232 |
1.87e-17 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 79.16 E-value: 1.87e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 4 VKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLK-LDTHDIIYMGisrt 81
Cdd:PRK15056 9 VNDVTVTWrNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQaLQKNLVAYVP---- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fQNLQLFQAMNVF-ENIYsgLIHKYNDSLFSVFSKSKmnfDKEAREKVLEVAEMFDIKNRLTSypsQLTYGMLKRVEMAR 160
Cdd:PRK15056 85 -QSEEVDWSFPVLvEDVV--MMGRYGHMGWLRRAKKR---DRQIVTAALARVDMVEFRHRQIG---ELSGGQKKRVFLAR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1341787947 161 AVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLvTVMNFGKKIAEGTPE 232
Cdd:PRK15056 156 AIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDY-TVMVKGTVLASGPTE 226
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-234 |
2.06e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 79.26 E-value: 2.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGesllkLDTHDiiymgis 79
Cdd:PRK13644 1 MIRLENVSYSYpDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG-----IDTGD------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 rtFQNLQLFQAMN--VFENIYSGLIHKYNDSLFSVFSKSKMNFDKEAREKV-LEVAEMFDIKNRLTSyPSQLTYGMLKRV 156
Cdd:PRK13644 69 --FSKLQGIRKLVgiVFQNPETQFVGRTVEEDLAFGPENLCLPPIEIRKRVdRALAEIGLEKYRHRS-PKTLSGGQGQCV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNvVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK13644 146 ALAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLE-ELHDADRIIVMDRGKIVLEGEPENV 222
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
3-233 |
2.47e-17 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 78.35 E-value: 2.47e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTF---GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHD----IIY 75
Cdd:cd03249 2 EFKNVSFRYpsrPDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWlrsqIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGisrtfQNLQLFqAMNVFENIysglihKYNDslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYP---------- 145
Cdd:cd03249 82 VS-----QEPVLF-DGTIAENI------RYGK-------------PDATDEEVEEAAKKANIHDFIMSLPdgydtlvger 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 146 -SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNvSDLVTVMNFGK 224
Cdd:cd03249 137 gSQLSGGQKQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRA-MKGRTTIVIAHRLSTIRN-ADLIAVLQNGQ 214
|
....*....
gi 1341787947 225 KIAEGTPED 233
Cdd:cd03249 215 VVEQGTHDE 223
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-222 |
3.80e-17 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 77.47 E-value: 3.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF-----GG--LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGES----LLKLD 69
Cdd:COG4778 4 LLEVENLSKTFtlhlqGGkrLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGgwvdLAQAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 70 THDIIY-----MG--------ISRTfqnlqlfQAMNVfenIYSGLIHkyndslfsvfskskMNFDK-EAREKVLEVAEMF 135
Cdd:COG4778 84 PREILAlrrrtIGyvsqflrvIPRV-------SALDV---VAEPLLE--------------RGVDReEARARARELLARL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 136 DIKNRL-TSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVS 214
Cdd:COG4778 140 NLPERLwDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVA 219
|
....*....
gi 1341787947 215 D-LVTVMNF 222
Cdd:COG4778 220 DrVVDVTPF 228
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-232 |
4.84e-17 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 77.76 E-value: 4.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLfntiTRIVNPH------KGDILFKGESLLKLDTHDII 74
Cdd:CHL00131 7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTL----SKVIAGHpaykilEGDILFKGESILDLEPEERA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMGISRTFQNLQLFQAMNvfeniysglihkyNDSLFSVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSY-PSQLTY--- 150
Cdd:CHL00131 83 HLGIFLAFQYPIEIPGVS-------------NADFLRLAYNSKRKFQGLPELDPLEFLEIINEKLKLVGMdPSFLSRnvn 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 -----GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVS-DLVTVMNFGK 224
Cdd:CHL00131 150 egfsgGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITHYQRLLDYIKpDYVHVMQNGK 229
|
....*...
gi 1341787947 225 KIAEGTPE 232
Cdd:CHL00131 230 IIKTGDAE 237
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
17-231 |
1.09e-16 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 77.03 E-value: 1.09e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 17 VNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiymgisRTFQ-NLQL-FQ----A 90
Cdd:PRK10419 28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQR------KAFRrDIQMvFQdsisA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 91 MN----VFENIYSGLIHKyndslfsvfskskMNFDKEARE-KVLEVAEMFDIKNRLTS-YPSQLTYGMLKRVEMARAVIS 164
Cdd:PRK10419 102 VNprktVREIIREPLRHL-------------LSLDKAERLaRASEMLRAVDLDDSVLDkRPPQLSGGQLQRVCLARALAV 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 165 DPDLLLLDEPAAGLN-YYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGkKIAEGTP 231
Cdd:PRK10419 169 EPKLLILDEAVSNLDlVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNG-QIVETQP 235
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-208 |
1.19e-16 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 77.05 E-value: 1.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFG-GL----KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIY 75
Cdd:COG1101 1 MLELKNLSKTFNpGTvnekRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MgISRTFQNLQLFQA--MNVFENiysgLIHKYND----SLFSVFSKSKMNFDKEArekvLEVAEMfDIKNRLTSYPSQLT 149
Cdd:COG1101 81 Y-IGRVFQDPMMGTApsMTIEEN----LALAYRRgkrrGLRRGLTKKRRELFREL----LATLGL-GLENRLDTKVGLLS 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMN 208
Cdd:COG1101 151 GGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTeKIVEENNLTTLMVTHNME 210
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
31-206 |
6.31e-16 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 74.43 E-value: 6.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 31 ALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYM---GISRTFQNLQLFQAMNVFENI-YSGLIHKYN 106
Cdd:PRK10584 40 ALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLrakHVGFVFQSFMLIPTLNALENVeLPALLRGES 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 107 DslfsvfskskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEI 186
Cdd:PRK10584 120 S--------------RQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKI 185
|
170 180
....*....|....*....|.
gi 1341787947 187 KSIIQMVNKR-GKTILLVEHD 206
Cdd:PRK10584 186 ADLLFSLNREhGTTLILVTHD 206
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
1-234 |
9.10e-16 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 75.16 E-value: 9.10e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGG----LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNpHKGDIL-----FKGESLLKL--- 68
Cdd:PRK11022 3 LLNVDKLSVHFGDesapFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLID-YPGRVMaekleFNGQDLQRIsek 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 69 DTHDIIYMGISRTFQN------------LQLFQAMNVFEniysglihkyndslfsvfSKSKmnfdKEAREKVLEVAEMFD 136
Cdd:PRK11022 82 ERRNLVGAEVAMIFQDpmtslnpcytvgFQIMEAIKVHQ------------------GGNK----KTRRQRAIDLLNQVG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 137 I---KNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNY-YETEEIKSIIQMVNKRGKTILLVEHDMNVVMN 212
Cdd:PRK11022 140 IpdpASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVtIQAQIIELLLELQQKENMALVLITHDLALVAE 219
|
250 260
....*....|....*....|..
gi 1341787947 213 VSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK11022 220 AAHKIIVMYAGQVVETGKAHDI 241
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
2-231 |
9.61e-16 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 73.68 E-value: 9.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFG-GLKAV-NDFSITISQG-KIhALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiymgi 78
Cdd:cd03244 3 IEFKNVSLRYRpNLPPVlKNISFSIKPGeKV-GIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL----- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 sRTF-----QNLQLFQAmNVFENIysGLIHKYNDS-LFSVFSKSKMnfdkeaREKVLEVAEMFDIknRLTSYPSQLTYGM 152
Cdd:cd03244 77 -RSRisiipQDPVLFSG-TIRSNL--DPFGEYSDEeLWQALERVGL------KEFVESLPGGLDT--VVEEGGENLSVGQ 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNyYETEE-IKSIIQMvNKRGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTP 231
Cdd:cd03244 145 RQLLCLARALLRKSKILVLDEATASVD-PETDAlIQKTIRE-AFKDCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDSP 221
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
16-229 |
1.72e-15 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 72.95 E-value: 1.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGE-SLLkldthdiiyMGISRTFQNlqlfqAMNVF 94
Cdd:cd03220 37 ALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRvSSL---------LGLGGGFNP-----ELTGR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 95 ENIY-SGLIHKYNdslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDE 173
Cdd:cd03220 103 ENIYlNGRLLGLS--------------RKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDE 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 174 P-AAGLNYYETEEIKSIIQMVnKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03220 169 VlAVGDAAFQEKCQRRLRELL-KQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
19-242 |
2.02e-15 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 75.14 E-value: 2.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDtHDIIYMGISRTFQNLQLFqAMNVFENIY 98
Cdd:TIGR00958 499 GLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYD-HHYLHRQVALVGQEPVLF-SGSVRENIA 576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 99 SGLihkyndslfsvfskskmnfDKEAREKVLEVAEMFDIKNRLTSYP-----------SQLTYGMLKRVEMARAVISDPD 167
Cdd:TIGR00958 577 YGL-------------------TDTPDEEIMAAAKAANAHDFIMEFPngydtevgekgSQLSGGQKQRIAIARALVRKPR 637
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 168 LLLLDEPAAGLNyyetEEIKSIIQMVNKR-GKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDIANNEEVVK 242
Cdd:TIGR00958 638 VLILDEATSALD----AECEQLLQESRSRaSRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQGCYK 708
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
3-230 |
2.50e-15 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 75.00 E-value: 2.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLK-AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGesllkLDTHDIIYMG---- 77
Cdd:PRK13657 336 EFDDVSFSYDNSRqGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDG-----TDIRTVTRASlrrn 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQLFqAMNVFENIYSGlihKYNDSlfsvfskskmnfDKEAREkVLEVAEMFD-IKNRLTSYP-------SQLT 149
Cdd:PRK13657 411 IAVVFQDAGLF-NRSIEDNIRVG---RPDAT------------DEEMRA-AAERAQAHDfIERKPDGYDtvvgergRQLS 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNyYETEE-IKSIIQMVNKrGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAE 228
Cdd:PRK13657 474 GGERQRLAIARALLKDPPILILDEATSALD-VETEAkVKAALDELMK-GRTTFIIAHRLSTVRN-ADRILVFDNGRVVES 550
|
..
gi 1341787947 229 GT 230
Cdd:PRK13657 551 GS 552
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-209 |
2.50e-15 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 75.15 E-value: 2.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDII-- 74
Cdd:PRK10535 4 LLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAql 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 ---YMGIsrTFQNLQLFQAMNVFEN-----IYSGLIHKyndslfsvfskskmnfdkEAREKVLEVAEMFDIKNRLTSYPS 146
Cdd:PRK10535 84 rreHFGF--IFQRYHLLSHLTAAQNvevpaVYAGLERK------------------QRLLRAQELLQRLGLEDRVEYQPS 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341787947 147 QLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNV 209
Cdd:PRK10535 144 QLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQV 206
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1-234 |
2.58e-15 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 73.29 E-value: 2.58e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF---GGL------KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfkgesllkLDTH 71
Cdd:PRK15112 4 LLEVRNLSKTFryrTGWfrrqtvEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELL--------IDDH 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 72 DIIYMGISRTFQNLQL-FQ----AMNVFENIysglihkynDSLFSVFSKSKMNFDKEAREK-VLEVAEMFDIK-NRLTSY 144
Cdd:PRK15112 76 PLHFGDYSYRSQRIRMiFQdpstSLNPRQRI---------SQILDFPLRLNTDLEPEQREKqIIETLRQVGLLpDHASYY 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 145 PSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNY-YETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFG 223
Cdd:PRK15112 147 PHMLAPGQKQRLGLARALILRPKVIIADEALASLDMsMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQG 226
|
250
....*....|.
gi 1341787947 224 KKIAEGTPEDI 234
Cdd:PRK15112 227 EVVERGSTADV 237
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-174 |
4.74e-15 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 74.20 E-value: 4.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFkGEsllkldTHDIIYMGISRT 81
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GE------TVKLAYVDQSRD 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fqnlQLFQAMNVFENIYSGlihkyNDSL----FSVFSK---SKMNFDKEAREKVLevaemfdiknrltsypSQLTYGMLK 154
Cdd:TIGR03719 396 ----ALDPNKTVWEEISGG-----LDIIklgkREIPSRayvGRFNFKGSDQQKKV----------------GQLSGGERN 450
|
170 180
....*....|....*....|
gi 1341787947 155 RVEMARAVISDPDLLLLDEP 174
Cdd:TIGR03719 451 RVHLAKTLKSGGNVLLLDEP 470
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
16-234 |
5.02e-15 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 72.13 E-value: 5.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDThDIIYMGISRTFQNLQLFQAmNVFE 95
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADP-AWLRRQVGVVLQENVLFNR-SIRD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 96 NIYSGlihkynDSLFSvfskskmnfdkeaREKVLEVAEMFDIKNRLTSYP-----------SQLTYGMLKRVEMARAVIS 164
Cdd:cd03252 95 NIALA------DPGMS-------------MERVIEAAKLAGAHDFISELPegydtivgeqgAGLSGGQRQRIAIARALIH 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1341787947 165 DPDLLLLDEPAAGLNyYETEEIksIIQMVNK--RGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDI 234
Cdd:cd03252 156 NPRILIFDEATSALD-YESEHA--IMRNMHDicAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDEL 223
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1-234 |
5.98e-15 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 73.74 E-value: 5.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF----GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfKGESLLKLDTHDIIYM 76
Cdd:PRK10261 12 VLAVENLNIAFmqeqQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQ-CDKMLLRRRSRQVIEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 G--------------ISRTFQN--LQLFQAMNVFENIYSGL-IHKyndslfsvfSKSKMNFDKEAReKVLEVAEMFDIKN 139
Cdd:PRK10261 91 SeqsaaqmrhvrgadMAMIFQEpmTSLNPVFTVGEQIAESIrLHQ---------GASREEAMVEAK-RMLDQVRIPEAQT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 140 RLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVT 218
Cdd:PRK10261 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEmSMGVIFITHDMGVVAEIADRVL 240
|
250
....*....|....*.
gi 1341787947 219 VMNFGKKIAEGTPEDI 234
Cdd:PRK10261 241 VMYQGEAVETGSVEQI 256
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1-215 |
6.67e-15 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 71.13 E-value: 6.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKldthdiiymgisr 80
Cdd:PRK13540 1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKK------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 tfqNLQLFQAMNVFENIYSGlIHKY----NDSLFSV-FSKSKMNFDkearekvlEVAEMFDIKNrLTSYP-SQLTYGMLK 154
Cdd:PRK13540 68 ---DLCTYQKQLCFVGHRSG-INPYltlrENCLYDIhFSPGAVGIT--------ELCRLFSLEH-LIDYPcGLLSSGQKR 134
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341787947 155 RVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDmNVVMNVSD 215
Cdd:PRK13540 135 QVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQEHRAKGGAVLLTSHQ-DLPLNKAD 194
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
21-238 |
7.48e-15 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 73.34 E-value: 7.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 21 SITISQGKIHALIGPNGAGKTTLFNTITRIVnPHKGDILFKGESLLKLDTHD----IIYMGisrtfQNLQLFQAmNVFEN 96
Cdd:PRK11174 370 NFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRELDPESwrkhLSWVG-----QNPQLPHG-TLRDN 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 97 IYSGlihkyndslfsvfsksKMNFDKEAREKVLEVAEMFDIKNRLT---SYP-----SQLTYGMLKRVEMARAVISDPDL 168
Cdd:PRK11174 443 VLLG----------------NPDASDEQLQQALENAWVSEFLPLLPqglDTPigdqaAGLSVGQAQRLALARALLQPCQL 506
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 169 LLLDEPAAGLNYYETEEIKSIIQmVNKRGKTILLVEHDMNVVMNVsDLVTVMNFGKKIAEGTPEDIANNE 238
Cdd:PRK11174 507 LLLDEPTASLDAHSEQLVMQALN-AASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQGDYAELSQAG 574
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-174 |
8.47e-15 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 73.18 E-value: 8.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQG-KIhALIGPNGAGKTTLFNTITRIVNPHKGDILFkGESLlkldthDIIYmgis 79
Cdd:COG0488 315 VLELEGLSKSYGDKTLLDDLSLRIDRGdRI-GLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV------KIGY---- 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 rtF-QNLQLFQA-MNVFENiysglIHKYNDSLFSVFSKS---KMNFDKEAREK---VL---EvaemfdiKNRLtsypsql 148
Cdd:COG0488 383 --FdQHQEELDPdKTVLDE-----LRDGAPGGTEQEVRGylgRFLFSGDDAFKpvgVLsggE-------KARL------- 441
|
170 180
....*....|....*....|....*.
gi 1341787947 149 tygMLkrvemARAVISDPDLLLLDEP 174
Cdd:COG0488 442 ---AL-----AKLLLSPPNVLLLDEP 459
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-234 |
1.04e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 71.69 E-value: 1.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLK---AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMg 77
Cdd:PRK13650 4 IIEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHK- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNL-QLFQAMNVFENIYSGLIHKYNDSlfsvfskskmnfdKEAREKV---LEVAEMFDIKNRltsYPSQLTYGML 153
Cdd:PRK13650 83 IGMVFQNPdNQFVGATVEDDVAFGLENKGIPH-------------EEMKERVneaLELVGMQDFKER---EPARLSGGQK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYY-ETEEIKSIIQMVNKRGKTILLVEHDMNVVMnVSDLVTVMNFGKKIAEGTPE 232
Cdd:PRK13650 147 QRVAIAGAVAMRPKIIILDEATSMLDPEgRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPR 225
|
..
gi 1341787947 233 DI 234
Cdd:PRK13650 226 EL 227
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
16-242 |
1.28e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 71.66 E-value: 1.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGesllkLDTHDI-----IYMGISRTFQNL--QLF 88
Cdd:PRK13633 25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDG-----LDTSDEenlwdIRNKAGMVFQNPdnQIV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 89 QAMnVFENIysglihkyndslfsVFSKSKMNFD-KEAREKV---LEVAEMFDIKNRLtsyPSQLTYGMLKRVEMARAVIS 164
Cdd:PRK13633 100 ATI-VEEDV--------------AFGPENLGIPpEEIRERVdesLKKVGMYEYRRHA---PHLLSGGQKQRVAIAGILAM 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 165 DPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDIANNEEVVK 242
Cdd:PRK13633 162 RPECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKEVEMMK 239
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
17-220 |
1.63e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 72.51 E-value: 1.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 17 VNDFSI----TISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDIlfkgESllKLDTHDIIymgisRTFQNLQLFqamN 92
Cdd:COG1245 85 ENGFRLyglpVPKKGKVTGILGPNGIGKSTALKILSGELKPNLGDY----DE--EPSWDEVL-----KRFRGTELQ---D 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 93 VFENIYSGLI---HK--YNDSLFSVFSKSKMNFDKEA--REKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISD 165
Cdd:COG1245 151 YFKKLANGEIkvaHKpqYVDLIPKVFKGTVRELLEKVdeRGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRD 230
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 166 PDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVM 220
Cdd:COG1245 231 ADFYFFDEPSSYLDIYQRLNVARLIRELAEEGKYVLVVEHDLAILDYLADYVHIL 285
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1-236 |
1.82e-14 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 72.43 E-value: 1.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLK-----------AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPhKGDILFKGESLLKLD 69
Cdd:PRK15134 275 LLDVEQLQVAFPIRKgilkrtvdhnvVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLINS-QGEIWFDGQPLHNLN 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 70 THDIIYM--GISRTFQ--NLQLFQAMNVFENIYSGL-IHKYNDSlfsvfskskmnfdKEARE-KVLEVAEM--FDIKNRl 141
Cdd:PRK15134 354 RRQLLPVrhRIQVVFQdpNSSLNPRLNVLQIIEEGLrVHQPTLS-------------AAQREqQVIAVMEEvgLDPETR- 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 142 TSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQ-MVNKRGKTILLVEHDMNVVMNVSDLVTVM 220
Cdd:PRK15134 420 HRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKsLQQKHQLAYLFISHDLHVVRALCHQVIVL 499
|
250
....*....|....*.
gi 1341787947 221 NFGKKIAEGTPEDIAN 236
Cdd:PRK15134 500 RQGEVVEQGDCERVFA 515
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
15-231 |
1.93e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 72.12 E-value: 1.93e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIH-----ALIGPNGAGKTTLFNTITRIVNPHKGDILFKgeslLKldthdiiymgISRTFQNLQLFQ 89
Cdd:COG1245 349 KSYGGFSLEVEGGEIRegevlGIVGPNGIGKTTFAKILAGVLKPDEGEVDED----LK----------ISYKPQYISPDY 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 90 AMNVFENIYSGLIHKYNDSLFSVfskskmnfdkearekvlEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLL 169
Cdd:COG1245 415 DGTVEEFLRSANTDDFGSSYYKT-----------------EIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLY 477
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1341787947 170 LLDEPAAGLNYYETEEIKSIIQ-MVNKRGKTILLVEHDMNVVMNVSDlvTVMNFgkkiaEGTP 231
Cdd:COG1245 478 LLDEPSAHLDVEQRLAVAKAIRrFAENRGKTAMVVDHDIYLIDYISD--RLMVF-----EGEP 533
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
3-234 |
4.70e-14 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 71.31 E-value: 4.70e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllKLDTHDII------YM 76
Cdd:NF033858 268 EARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQ---PVDAGDIAtrrrvgYM 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 giSRTF---------QNLQLfqamnvfeniysgliHKyndSLFSVFskskmnfDKEAREKVLEVAEMFDIKNRLTSYPSQ 147
Cdd:NF033858 345 --SQAFslygeltvrQNLEL---------------HA---RLFHLP-------AAEIAARVAEMLERFDLADVADALPDS 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAGL------NYYETeeiksIIQMVNKRGKTILLVEHDMNVVMNVsDLVTVMN 221
Cdd:NF033858 398 LPLGIRQRLSLAVAVIHKPELLILDEPTSGVdpvardMFWRL-----LIELSREDGVTIFISTHFMNEAERC-DRISLMH 471
|
250
....*....|...
gi 1341787947 222 FGKKIAEGTPEDI 234
Cdd:NF033858 472 AGRVLASDTPAAL 484
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
2-234 |
7.91e-14 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 70.55 E-value: 7.91e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKA--VNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLD-----THdII 74
Cdd:COG4618 331 LSVENLTVVPPGSKRpiLRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDreelgRH-IG 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMGisrtfQNLQLFQAmNVFENIysglihkyndslfsvfskskmnfdkeAR------EKVLEVAEMFDIKNRLTSYP--- 145
Cdd:COG4618 410 YLP-----QDVELFDG-TIAENI--------------------------ARfgdadpEKVVAAAKLAGVHEMILRLPdgy 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 146 --------SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNvVMNVSDLV 217
Cdd:COG4618 458 dtrigeggARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVITHRPS-LLAAVDKL 536
|
250
....*....|....*..
gi 1341787947 218 TVMNFGKKIAEGTPEDI 234
Cdd:COG4618 537 LVLRDGRVQAFGPRDEV 553
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1-232 |
8.06e-14 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 68.59 E-value: 8.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDThDIIYMGISR 80
Cdd:PRK10247 7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKP-EIYRQQVSY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQamnvfENIYSGLIHKYndslfsvfsksKMNFDKEAREKVLEVAEMFDI-KNRLTSYPSQLTYGMLKRVEMA 159
Cdd:PRK10247 86 CAQTPTLFG-----DTVYDNLIFPW-----------QIRNQQPDPAIFLDDLERFALpDTILTKNIAELSGGEKQRISLI 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPE 232
Cdd:PRK10247 150 RNLQFMPKVLLLDEITSALDESNKHNVNEIIhRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQEARYE 223
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
2-238 |
8.70e-14 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 70.42 E-value: 8.70e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTfgglkAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHD-----IIYM 76
Cdd:PRK10762 258 LKVDNLSGP-----GVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDglangIVYI 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQNLQLfqAMNVFENIysglihkyndSLFSV--FSKSKMNFD-KEAREKVLEVAEMFDIKNrltsyPSQ------ 147
Cdd:PRK10762 333 SEDRKRDGLVL--GMSVKENM----------SLTALryFSRAGGSLKhADEQQAVSDFIRLFNIKT-----PSMeqaigl 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIA 227
Cdd:PRK10762 396 LSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRISG 475
|
250
....*....|.
gi 1341787947 228 EGTPEDiANNE 238
Cdd:PRK10762 476 EFTREQ-ATQE 485
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
2-234 |
8.88e-14 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 68.96 E-value: 8.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLkAVNDFSITISQGKIHALIGPNGAGKT----TLFNTITRIVNPHKGDILFKGESLLKLDTHDIIymg 77
Cdd:PRK10418 5 IELRNIALQAAQP-LVHGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKPVAPCALRGRK--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNLQlfQAMNVFENIYSGLIHkyndslfSVFSKSKMNFDKEAREkVLEVAEMFDIKNRLTSYPSQLTYGMLKRVE 157
Cdd:PRK10418 81 IATIMQNPR--SAFNPLHTMHTHARE-------TCLALGKPADDATLTA-ALEAVGLENAARVLKLYPFEMSGGMLQRMM 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 158 MARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQ-MVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDI 234
Cdd:PRK10418 151 IALALLCEAPFIIADEPTTDLDVVAQARILDLLEsIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETL 228
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
2-234 |
2.10e-13 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 69.28 E-value: 2.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLK--AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfkgesllkLDTHDII-Ymgi 78
Cdd:PRK11176 342 IEFRNVTFTYPGKEvpALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEIL--------LDGHDLRdY--- 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 srTFQNLQLFQAMnVFENIysgliHKYNDSLFSVFSKSKMnfDKEAREKVLEVAEM-----FDIK--NRLTSYPSQ---- 147
Cdd:PRK11176 411 --TLASLRNQVAL-VSQNV-----HLFNDTIANNIAYART--EQYSREQIEEAARMayamdFINKmdNGLDTVIGEngvl 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKrGKTILLVEHDMNVVMNvSDLVTVMNFGKKIA 227
Cdd:PRK11176 481 LSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQK-NRTSLVIAHRLSTIEK-ADEILVVEDGEIVE 558
|
....*..
gi 1341787947 228 EGTPEDI 234
Cdd:PRK11176 559 RGTHAEL 565
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
20-244 |
2.68e-13 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 67.17 E-value: 2.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 20 FSITISQGKIHALIGPNGAGKTTLfntITRI--VNPHKGDILFKGESLLKLDTHDIIYMgisRTF---QNLQLFqAMNVF 94
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTL---LARMagLLPGQGEILLNGRPLSDWSAAELARH---RAYlsqQQSPPF-AMPVF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 95 ENIysglihkyndSLFSvfskSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVI-----SDPD-- 167
Cdd:COG4138 88 QYL----------ALHQ----PAGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptINPEgq 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 168 LLLLDEPAAGLNyyeteeiksIIQ--MVNK-------RGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIANNE 238
Cdd:COG4138 154 LLLLDEPMNSLD---------VAQqaALDRllrelcqQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPE 224
|
....*.
gi 1341787947 239 EVVKVY 244
Cdd:COG4138 225 NLSEVF 230
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
2-205 |
9.35e-13 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 65.07 E-value: 9.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTH---DIIYMGI 78
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEpheNILYLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTfqnlqLFQAMNVFENiysglIHKYNDslfsvFSKSKMNFDKEArekvLEVAEMFDIKNRLTsypSQLTYGMLKRVEM 158
Cdd:TIGR01189 81 LPG-----LKPELSALEN-----LHFWAA-----IHGGAQRTIEDA----LAAVGLTGFEDLPA---AQLSAGQQRRLAL 138
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEH 205
Cdd:TIGR01189 139 ARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAHLARGGIVLLTTH 185
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1-245 |
1.23e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 65.88 E-value: 1.23e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF---GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDiIYMG 77
Cdd:PRK13642 4 ILEVENLVFKYekeSDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWN-LRRK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ISRTFQNL-QLFQAMNVFENIYSGLIHKyndslfsvfSKSKMNFDKEAREKVLEVaEMFDIKNRltsYPSQLTYGMLKRV 156
Cdd:PRK13642 83 IGMVFQNPdNQFVGATVEDDVAFGMENQ---------GIPREEMIKRVDEALLAV-NMLDFKTR---EPARLSGGQKQRV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 157 EMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMV-NKRGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDI- 234
Cdd:PRK13642 150 AVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIkEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELf 228
|
250
....*....|.
gi 1341787947 235 ANNEEVVKVYL 245
Cdd:PRK13642 229 ATSEDMVEIGL 239
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
2-210 |
3.73e-12 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 63.28 E-value: 3.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKldTHDIIYMGISRT 81
Cdd:cd03231 1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDF--QRDSIARGLLYL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 FQNLQLFQAMNVFENIYsgLIHKYNDslfsvfskskmnfdkeaREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARA 161
Cdd:cd03231 79 GHAPGIKTTLSVLENLR--FWHADHS-----------------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARL 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1341787947 162 VISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEH-DMNVV 210
Cdd:cd03231 140 LLSGRPLWILDEPTTALDKAGVARFAEAMAGHCARGGMVVLTTHqDLGLS 189
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-244 |
4.27e-12 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 64.46 E-value: 4.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNT----ITRIVNPH----KGDILFKGESLLKLDTHD 72
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKAlagdLTGGGAPRgarvTGDVTLNGEPLAAIDAPR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 73 IIYMGISRTFQNLQLFqAMNVFENIysgLIHKYNDSLfsvFSKSKMNFDKEAREKVLEVAEMFDIKNRLTsypSQLTYGM 152
Cdd:PRK13547 81 LARLRAVLPQAAQPAF-AFSAREIV---LLGRYPHAR---RAGALTHRDGEIAWQALALAGATALVGRDV---TTLSGGE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 153 LKRVEMARAV---------ISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKT-ILLVEHDMNVVMNVSDLVTVMNF 222
Cdd:PRK13547 151 LARVQFARVLaqlwpphdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLgVLAIVHDPNLAARHADRIAMLAD 230
|
250 260
....*....|....*....|..
gi 1341787947 223 GKKIAEGTPEDIANNEEVVKVY 244
Cdd:PRK13547 231 GAIVAHGAPADVLTPAHIARCY 252
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-224 |
4.33e-12 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 65.23 E-value: 4.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVT---VTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIV-NPHKGDILFKGESLLKLDTHDIIYM 76
Cdd:TIGR02633 257 ILEARNLTcwdVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYpGKFEGNVFINGKPVDIRNPAQAIRA 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQNLQ---LFQAMNVFENIYSGLIHKYNdslfsvfskSKMNFDKEAREKVLEvAEMFDIKNRlTSYP----SQLT 149
Cdd:TIGR02633 337 GIAMVPEDRKrhgIVPILGVGKNITLSVLKSFC---------FKMRIDAAAELQIIG-SAIQRLKVK-TASPflpiGRLS 405
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 150 YGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:TIGR02633 406 GGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGK 480
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1-231 |
5.24e-12 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 65.26 E-value: 5.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTF---GGL--------KAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllKLD 69
Cdd:PRK10261 313 ILQVRNLVTRFplrSGLlnrvtrevHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQ---RID 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 70 THDIIYMGISRtfQNLQLfqamnVFENIYSGL--IHKYNDSLFSVFSKSKMNFDKEAREKVLEVAEMFDIK-NRLTSYPS 146
Cdd:PRK10261 390 TLSPGKLQALR--RDIQF-----IFQDPYASLdpRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLpEHAWRYPH 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 147 QLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNY-YETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGkK 225
Cdd:PRK10261 463 EFSGGQRQRICIARALALNPKVIIADEAVSALDVsIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLG-Q 541
|
....*.
gi 1341787947 226 IAEGTP 231
Cdd:PRK10261 542 IVEIGP 547
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-237 |
8.54e-12 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 63.49 E-value: 8.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDilfkgESLLKLDTHDIIYMG--- 77
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSA-----GSHIELLGRTVQREGrla 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ----ISRT-----FQNLQLFQAMNVFENIYSGLIHK--YNDSLFSVFSKSKmnfDKEAREKVLEVAEMFDIKNRLtsypS 146
Cdd:PRK09984 79 rdirKSRAntgyiFQQFNLVNRLSVLENVLIGALGStpFWRTCFSWFTREQ---KQRALQALTRVGMVHFAHQRV----S 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 147 QLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKR-GKTILLVEHDMNVVMNVSDLVTVMNFGKK 225
Cdd:PRK09984 152 TLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVALRQGHV 231
|
250
....*....|..
gi 1341787947 226 IAEGTPEDIANN 237
Cdd:PRK09984 232 FYDGSSQQFDNE 243
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
2-205 |
1.22e-11 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 62.95 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF--GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPhKGDILFKGESLLKLdthdiiymgis 79
Cdd:cd03289 3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNT-EGDIQIDGVSWNSV----------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 rTFQnlQLFQAMNVFEN---IYSGLIHKYNDSlfsvfskskmnFDKEAREKVLEVAEMFDIKNRLTSYPSQ--------- 147
Cdd:cd03289 71 -PLQ--KWRKAFGVIPQkvfIFSGTFRKNLDP-----------YGKWSDEEIWKVAEEVGLKSVIEQFPGQldfvlvdgg 136
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 --LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKrGKTILLVEH 205
Cdd:cd03289 137 cvLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQAFA-DCTVILSEH 195
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
15-231 |
1.37e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 63.67 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIHA-----LIGPNGAGKTTLFNTITRIVNPHKGDILFKgeslLKldthdiiymgISRTFQNLQLFQ 89
Cdd:PRK13409 348 KKLGDFSLEVEGGEIYEgevigIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE----LK----------ISYKPQYIKPDY 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 90 AMNVFENIYSgLIHKYNDSLFSVfskskmnfdkearekvlEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLL 169
Cdd:PRK13409 414 DGTVEDLLRS-ITDDLGSSYYKS-----------------EIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLY 475
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 170 LLDEPAAglnYYETEE----IKSIIQMVNKRGKTILLVEHDMNVVMNVSDlvTVMNFgkkiaEGTP 231
Cdd:PRK13409 476 LLDEPSA---HLDVEQrlavAKAIRRIAEEREATALVVDHDIYMIDYISD--RLMVF-----EGEP 531
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-242 |
1.70e-11 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 63.65 E-value: 1.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTfgGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGI-- 78
Cdd:PRK09700 265 VFEVRNVTSR--DRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDAVKKGMay 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 ---SRT----FQNLQLFQAMNVFENIYSGlihKYNDSLFSVFSKSKMNFDKEAREKVlevaemfDIK-NRLTSYPSQLTY 150
Cdd:PRK09700 343 iteSRRdngfFPNFSIAQNMAISRSLKDG---GYKGAMGLFHEVDEQRTAENQRELL-------ALKcHSVNQNITELSG 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGT 230
Cdd:PRK09700 413 GNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILT 492
|
250
....*....|..
gi 1341787947 231 PEDIANNEEVVK 242
Cdd:PRK09700 493 NRDDMSEEEIMA 504
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
2-174 |
2.22e-11 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 63.21 E-value: 2.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFkGEsllkldTHDIIYMGISRt 81
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GE------TVKLAYVDQSR- 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 82 fqnlqlfQAM----NVFENIYSGL-IHKYNDslFSVFSK---SKMNF---DKEAREKVLEVAEmfdiKNrltsypsqlty 150
Cdd:PRK11819 397 -------DALdpnkTVWEEISGGLdIIKVGN--REIPSRayvGRFNFkggDQQKKVGVLSGGE----RN----------- 452
|
170 180
....*....|....*....|....
gi 1341787947 151 gmlkRVEMARAVISDPDLLLLDEP 174
Cdd:PRK11819 453 ----RLHLAKTLKQGGNVLLLDEP 472
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1-205 |
3.14e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 61.04 E-value: 3.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllklDTHD------II 74
Cdd:PRK13539 2 MLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGG-----DIDDpdvaeaCH 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 75 YMGisrtFQNlqlfqAMN----VFENIysglihkyndslfsVFSKskmNFDKEAREKVLEVAEMFDIkNRLTSYPsqltY 150
Cdd:PRK13539 77 YLG----HRN-----AMKpaltVAENL--------------EFWA---AFLGGEELDIAAALEAVGL-APLAHLP----F 125
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 GML-----KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEH 205
Cdd:PRK13539 126 GYLsagqkRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAHLAQGGIVIAATH 185
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
27-220 |
3.21e-11 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 61.61 E-value: 3.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 27 GKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllkldthdiiYMGISRTFQNLQLfqaMNVFENIYSG---LIH 103
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPD-----------WDEILDEFRGSEL---QNYFTKLLEGdvkVIV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 104 K--YNDSLFSVFS-KSKMNFDK-EAREKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLN 179
Cdd:cd03236 92 KpqYVDLIPKAVKgKVGELLKKkDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLD 171
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1341787947 180 YYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVM 220
Cdd:cd03236 172 IKQRLNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCL 212
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
15-219 |
3.53e-11 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 61.27 E-value: 3.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGKIH-----ALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESllkldthdiiymgISRTFQNLQLFQ 89
Cdd:cd03237 8 KTLGEFTLEVEGGSISeseviGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDT-------------VSYKPQYIKADY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 90 AMNVFENIYSGLIHKYNDSLFSVfskskmnfdkearekvlEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLL 169
Cdd:cd03237 75 EGTVRDLLSSITKDFYTHPYFKT-----------------EIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIY 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 170 LLDEPAAglnYYETEE----IKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTV 219
Cdd:cd03237 138 LLDEPSA---YLDVEQrlmaSKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV 188
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
1-207 |
7.43e-11 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 61.95 E-value: 7.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLK--AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLkldthdiiyMGI 78
Cdd:TIGR01257 1937 ILRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIL---------TNI 2007
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNLQLFQAMNVFENIYSGLIHKYndslfsVFSKSKmNFDKEAREKVLEvaemFDIKNR-LTSYPSQL--TY--GML 153
Cdd:TIGR01257 2008 SDVHQNMGYCPQFDAIDDLLTGREHLY------LYARLR-GVPAEEIEKVAN----WSIQSLgLSLYADRLagTYsgGNK 2076
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDM 207
Cdd:TIGR01257 2077 RKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSM 2130
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
2-229 |
1.31e-10 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 59.10 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVT------FGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTIT-RIVNPH-KGDILFKGESLLKLDTHDI 73
Cdd:cd03213 4 LSFRNLTVTvksspsKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgRRTGLGvSGEVLINGRPLDKRSFRKI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 IYMgisrTFQNLQLFQAMNVFENIYsglihkyndslFSvfskskmnfdkearekvlevAEMfdiknrltsypSQLTYGML 153
Cdd:cd03213 84 IGY----VPQDDILHPTLTVRETLM-----------FA--------------------AKL-----------RGLSGGER 117
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDM-NVVMNVSDLVTVMNFGKKIAEG 229
Cdd:cd03213 118 KRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-229 |
1.53e-10 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 59.55 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESllkLDTHDIIYMG--- 77
Cdd:PRK11701 6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRD---GQLRDLYALSeae 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ---ISRT-----FQN------LQLFQAMNVFENIYS-GLIHkYNDslfsvfskskmnfdkeAREKVLEVAEMFDI-KNRL 141
Cdd:PRK11701 83 rrrLLRTewgfvHQHprdglrMQVSAGGNIGERLMAvGARH-YGD----------------IRATAGDWLERVEIdAARI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 142 TSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSII-QMVNKRGKTILLVEHDMNVVMNVSDLVTVM 220
Cdd:PRK11701 146 DDLPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLrGLVRELGLAVVIVTHDLAVARLLAHRLLVM 225
|
....*....
gi 1341787947 221 NFGKKIAEG 229
Cdd:PRK11701 226 KQGRVVESG 234
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
2-234 |
1.89e-10 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 60.13 E-value: 1.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTlFNTITRIVNPHKGDILFKGESLL--------KLDTHDI 73
Cdd:NF000106 14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGRRPWRF*TWCanrralrrTIG*HRP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 IYMGISRTFQNLqlfqamnvfENIYsgLIHKYNDslfsvFSKskmnfdKEAREKVLEVAEMFDIKNRLTSYPSQLTYGML 153
Cdd:NF000106 93 VR*GRRESFSGR---------ENLY--MIGR*LD-----LSR------KDARARADELLERFSLTEAAGRAAAKYSGGMR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 KRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPED 233
Cdd:NF000106 151 RRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDE 230
|
.
gi 1341787947 234 I 234
Cdd:NF000106 231 L 231
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
2-206 |
1.93e-10 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 60.37 E-value: 1.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLK-AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIiymgisr 80
Cdd:PRK10522 323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDY------- 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 tfqnLQLFQAmnVFENIYsglihkyndsLFS-VFSKSKMNFDKEAREKVLEVAEMFD----IKNRLTSypSQLTYGMLKR 155
Cdd:PRK10522 396 ----RKLFSA--VFTDFH----------LFDqLLGPEGKPANPALVEKWLERLKMAHklelEDGRISN--LKLSKGQKKR 457
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1341787947 156 VEMARAVISDPDLLLLDEPAAGLN-YYETEEIKSIIQMVNKRGKTILLVEHD 206
Cdd:PRK10522 458 LALLLALAEERDILLLDEWAADQDpHFRREFYQVLLPLLQEMGKTIFAISHD 509
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
1-229 |
3.11e-10 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 58.65 E-value: 3.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTIT--RIVNPHKGDILFKGESLLKLDTHDIIYMGI 78
Cdd:PRK09580 1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAgrEDYEVTGGTVEFKGKDLLELSPEDRAGEGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQ-NLQLFQAMNVFeniysglihkyndslfsvFSKSKMNFDKEAREKV----LEVAEMFDIKNRLTSYPSQL----- 148
Cdd:PRK09580 81 FMAFQyPVEIPGVSNQF------------------FLQTALNAVRSYRGQEpldrFDFQDLMEEKIALLKMPEDLltrsv 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 149 ----TYGMLKRVEMARAVISDPDLLLLDEPAAGLnyyETEEIKSIIQMVN--KRGK-TILLVEHDMNVVMNVS-DLVTVM 220
Cdd:PRK09580 143 nvgfSGGEKKRNDILQMAVLEPELCILDESDSGL---DIDALKIVADGVNslRDGKrSFIIVTHYQRILDYIKpDYVHVL 219
|
....*....
gi 1341787947 221 NFGKKIAEG 229
Cdd:PRK09580 220 YQGRIVKSG 228
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
2-231 |
4.17e-10 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 57.81 E-value: 4.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGG--LKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHD------- 72
Cdd:cd03369 7 IEVENLSVRYAPdlPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDlrsslti 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 73 -----IIYMGISRTfqNLQLFqamnvfeNIYSglihkyndslfsvfskskmnfDKEAREkVLEVAEMfdiknrltsyPSQ 147
Cdd:cd03369 87 ipqdpTLFSGTIRS--NLDPF-------DEYS---------------------DEEIYG-ALRVSEG----------GLN 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKrGKTILLVEHDMNVVMNVsDLVTVMNFGKKIA 227
Cdd:cd03369 126 LSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIREEFT-NSTILTIAHRLRTIIDY-DKILVMDAGEVKE 203
|
....
gi 1341787947 228 EGTP 231
Cdd:cd03369 204 YDHP 207
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
21-239 |
8.97e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 58.60 E-value: 8.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 21 SITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfkgesllkLDTHDIIYMGISRTFQNLQLFQAMNVfenIYSG 100
Cdd:PLN03130 1259 SFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRIL--------IDGCDISKFGLMDLRKVLGIIPQAPV---LFSG 1327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 101 LI-------HKYNDS----------LFSVFSKSKMNFDKEarekVLEVAEMFDIKNRltsypsQLtygmlkrVEMARAVI 163
Cdd:PLN03130 1328 TVrfnldpfNEHNDAdlweslerahLKDVIRRNSLGLDAE----VSEAGENFSVGQR------QL-------LSLARALL 1390
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 164 SDPDLLLLDEPAAGLNYYETEEIKSIIQMvNKRGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDIANNEE 239
Cdd:PLN03130 1391 RRSKILVLDEATAAVDVRTDALIQKTIRE-EFKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLSNEG 1464
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
2-221 |
1.71e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.73 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAV---NDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGI 78
Cdd:PTZ00265 383 IQFKNVRFHYDTRKDVeiyKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSHNLKDINLKWWRSKI 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNLQLFQ---AMNVFENIYS-----GLIHKYNDSLFSVFSKS-----------------------------KMNFD 121
Cdd:PTZ00265 463 GVVSQDPLLFSnsiKNNIKYSLYSlkdleALSNYYNEDGNDSQENKnkrnscrakcagdlndmsnttdsneliemRKNYQ 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 122 KEAREKVLEVAEMFDIKNRLTSYP-----------SQLTYGMLKRVEMARAVISDPDLLLLDEPAAGL-NYYETEEIKSI 189
Cdd:PTZ00265 543 TIKDSEVVDVSKKVLIHDFVSALPdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLdNKSEYLVQKTI 622
|
250 260 270
....*....|....*....|....*....|..
gi 1341787947 190 IQMVNKRGKTILLVEHDMNVVMNVSDLVTVMN 221
Cdd:PTZ00265 623 NNLKGNENRITIIIAHRLSTIRYANTIFVLSN 654
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1-174 |
1.81e-09 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 55.97 E-value: 1.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDT---HDIIYMG 77
Cdd:PRK13538 1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDeyhQDLLYLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 78 ----ISR---TFQNLQLFQAMnvfeniySGLIHkyndslfsvfskskmnfdkeaREKVLEVAEMFDIKNRLTSYPSQLTY 150
Cdd:PRK13538 81 hqpgIKTeltALENLRFYQRL-------HGPGD---------------------DEALWEALAQVGLAGFEDVPVRQLSA 132
|
170 180
....*....|....*....|....
gi 1341787947 151 GMLKRVEMARAVISDPDLLLLDEP 174
Cdd:PRK13538 133 GQQRRVALARLWLTRAPLWILDEP 156
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
27-232 |
1.92e-09 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 57.36 E-value: 1.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 27 GKIHALIGPNGAGKTTLFNTIT-RIVNPHK--GDILFKGESLlkldthdiiymgisrtfqNLQLFQAMNVF---ENIYSG 100
Cdd:TIGR00955 51 GELLAVMGSSGAGKTTLMNALAfRSPKGVKgsGSVLLNGMPI------------------DAKEMRAISAYvqqDDLFIP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 101 LIHKYNDSLFSVFSKSKMNFDK-EAREKVLEVAEMF---DIKNRLTSYPSQ---LTYGMLKRVEMARAVISDPDLLLLDE 173
Cdd:TIGR00955 113 TLTVREHLMFQAHLRMPRRVTKkEKRERVDEVLQALglrKCANTRIGVPGRvkgLSGGERKRLAFASELLTDPPLLFCDE 192
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 174 PAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNV-VMNVSDLVTVMNFGKKIAEGTPE 232
Cdd:TIGR00955 193 PTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSeLFELFDKIILMAEGRVAYLGSPD 252
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
19-249 |
1.99e-09 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 57.37 E-value: 1.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHD-----IIYMGISRtfQNLQLFQAMNV 93
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQrlargLVYLPEDR--QSSGLYLDAPL 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 94 FENIYSgLIHkyNDSLFsvfskskmnFDKEARE-KVLE-VAEMFDIKnrlTSYPSQ----LTYGMLKRVEMARAVISDPD 167
Cdd:PRK15439 359 AWNVCA-LTH--NRRGF---------WIKPAREnAVLErYRRALNIK---FNHAEQaartLSGGNQQKVLIAKCLEASPQ 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 168 LLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGKKIAEGTPEDIaNNEEVVKVYLGE 247
Cdd:PRK15439 424 LLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEISGALTGAAI-NVDTIMRLAFGE 502
|
..
gi 1341787947 248 DE 249
Cdd:PRK15439 503 HQ 504
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
2-224 |
2.71e-09 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 55.17 E-value: 2.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDF-----SITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGesllkldthdiiym 76
Cdd:cd03250 1 ISVEDASFTWDSGEQETSFtlkdiNLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG-------------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 77 GISRTFQNLQLFQAmNVFENIysglihkyndslfsVFSKSkmnFDKEAREKVLEVAEMF-DIKnrltsypsQLTYGML-- 153
Cdd:cd03250 67 SIAYVSQEPWIQNG-TIRENI--------------LFGKP---FDEERYEKVIKACALEpDLE--------ILPDGDLte 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 154 -------------KRVEMARAVISDPDLLLLDEPAAGLNyYETEE--IKSIIQMVNKRGKTILLVEHDMNVVMNVsDLVT 218
Cdd:cd03250 121 igekginlsggqkQRISLARAVYSDADIYLLDDPLSAVD-AHVGRhiFENCILGLLLNNKTRILVTHQLQLLPHA-DQIV 198
|
....*.
gi 1341787947 219 VMNFGK 224
Cdd:cd03250 199 VLDNGR 204
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-224 |
6.11e-09 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 55.71 E-value: 6.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVT---VTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRiVNP--HKGDILFKGESLLKLDTHDIIY 75
Cdd:PRK13549 259 ILEVRNLTawdPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFG-AYPgrWEGEIFIDGKPVKIRNPQQAIA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MGIS-----RTFQNLQLfqAMNVFENIYSGLIHKYndSLFSVFskskmnfDKEAREKVLEvAEMFDIKNRlTSYP----S 146
Cdd:PRK13549 338 QGIAmvpedRKRDGIVP--VMGVGKNITLAALDRF--TGGSRI-------DDAAELKTIL-ESIQRLKVK-TASPelaiA 404
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 147 QLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:PRK13549 405 RLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGK 482
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
2-245 |
6.28e-09 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 55.69 E-value: 6.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTfgGLKAvnDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGI--- 78
Cdd:PRK11288 258 LRLDGLKGP--GLRE--PISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGImlc 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 --SRTFQNLqlFQAMNVFENIysglihkyNDSLFSVFSKSKM--NFDKEAREKVLEVAEMfDIKnrlTSYPSQ----LTY 150
Cdd:PRK11288 334 peDRKAEGI--IPVHSVADNI--------NISARRHHLRAGCliNNRWEAENADRFIRSL-NIK---TPSREQlimnLSG 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGkKIAEGT 230
Cdd:PRK11288 400 GNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREG-RIAGEL 478
|
250
....*....|....*
gi 1341787947 231 PEDIANNEEVVKVYL 245
Cdd:PRK11288 479 AREQATERQALSLAL 493
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
2-245 |
6.79e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 56.19 E-value: 6.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAV---NDFSITISQGKIHALIGPNGAGKTTLFNTITR---IVNPHKgdILFKGESLLKLdTHDIIY 75
Cdd:PTZ00265 1166 IEIMDVNFRYISRPNVpiyKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRfydLKNDHH--IVFKNEHTNDM-TNEQDY 1242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 76 MG---ISRTFQNLQLFQAMN---------VFEN----IYSGL-IHKYN----DSLFSVFSKSKM----------NFDKE- 123
Cdd:PTZ00265 1243 QGdeeQNVGMKNVNEFSLTKeggsgedstVFKNsgkiLLDGVdICDYNlkdlRNLFSIVSQEPMlfnmsiyeniKFGKEd 1322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 124 -AREKVLEVAEMFDIKNRLTSYPSQ-----------LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEI-KSII 190
Cdd:PTZ00265 1323 aTREDVKRACKFAAIDEFIESLPNKydtnvgpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIeKTIV 1402
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341787947 191 QMVNKRGKTILLVEHDMNVVMNvSDLVTVMNFGKKI-----AEGTPEDIANNEE-VVKVYL 245
Cdd:PTZ00265 1403 DIKDKADKTIITIAHRIASIKR-SDKIVVFNNPDRTgsfvqAHGTHEELLSVQDgVYKKYV 1462
|
|
| BCA_ABC_TP_C |
pfam12399 |
Branched-chain amino acid ATP-binding cassette transporter; This domain family is found in ... |
224-248 |
6.91e-09 |
|
Branched-chain amino acid ATP-binding cassette transporter; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00005. There is a conserved AYLG sequence motif. This family is the C terminal of an ATP dependent branched-chain amino acid transporter. This domain is essential for LPS transport, through critical interactions with Walker A and switch helix domains.
Pssm-ID: 463560 Cd Length: 25 Bit Score: 49.94 E-value: 6.91e-09
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
19-216 |
7.18e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 54.11 E-value: 7.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGisrtfQNLQLFQAMNVFENIy 98
Cdd:PRK13541 18 DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPYCTYIG-----HNLGLKLEMTVFENL- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 99 sglihkyndSLFSVFSKSKmnfdkearEKVLEVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGL 178
Cdd:PRK13541 92 ---------KFWSEIYNSA--------ETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNL 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 1341787947 179 NYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDL 216
Cdd:PRK13541 155 SKENRDLLNNLIVMKANSGGIVLLSSHLESSIKSAQIL 192
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
20-238 |
7.60e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 55.75 E-value: 7.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 20 FSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILfkgesllkLDTHDIIYMGISRTFQNLQLFQAMNVfenIYS 99
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIM--------IDDCDVAKFGLTDLRRVLSIIPQSPV---LFS 1323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 100 GLIH-------KYNDS----------LFSVFSKSKMNFDKEarekVLEVAEMFDIKNRltsypsQLtygmlkrVEMARAV 162
Cdd:PLN03232 1324 GTVRfnidpfsEHNDAdlwealerahIKDVIDRNPFGLDAE----VSEGGENFSVGQR------QL-------LSLARAL 1386
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 163 ISDPDLLLLDEPAAGLNYyeteEIKSIIQMVNK---RGKTILLVEHDMNVVMNVsDLVTVMNFGKKIAEGTPEDIANNE 238
Cdd:PLN03232 1387 LRRSKILVLDEATASVDV----RTDSLIQRTIReefKSCTMLVIAHRLNTIIDC-DKILVLSSGQVLEYDSPQELLSRD 1460
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
16-210 |
1.23e-08 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 54.90 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLkldthdiiyMGISRTFQNlqlfqAMNVFE 95
Cdd:PRK13545 39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAAL---------IAISSGLNG-----QLTGIE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 96 NI-YSGLIHKyndslfsvFSKSKMnfdKEAREKVLEVAEMFDIKNR-LTSYPSqltyGMLKRVEMARAVISDPDLLLLDE 173
Cdd:PRK13545 105 NIeLKGLMMG--------LTKEKI---KEIIPEIIEFADIGKFIYQpVKTYSS----GMKSRLGFAISVHINPDILVIDE 169
|
170 180 190
....*....|....*....|....*....|....*..
gi 1341787947 174 PAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVV 210
Cdd:PRK13545 170 ALSVGDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQV 206
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
19-234 |
1.48e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 54.95 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMgISRTFQNLQLFqamnvfeniy 98
Cdd:TIGR00957 1304 HINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFK-ITIIPQDPVLF---------- 1372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 99 SGLIhKYNDSLFSVFSKskmnfdkearEKVLEVAEMFDIKNRLTSYPSQLTY-----------GMLKRVEMARAVISDPD 167
Cdd:TIGR00957 1373 SGSL-RMNLDPFSQYSD----------EEVWWALELAHLKTFVSALPDKLDHecaeggenlsvGQRQLVCLARALLRKTK 1441
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 168 LLLLDEPAAGLNYYETEEIKSIIQmVNKRGKTILLVEHDMNVVMNVSDlVTVMNFGKKIAEGTPEDI 234
Cdd:TIGR00957 1442 ILVLDEATAAVDLETDNLIQSTIR-TQFEDCTVLTIAHRLNTIMDYTR-VIVLDKGEVAEFGAPSNL 1506
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
2-231 |
2.52e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 54.18 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTF--GGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllkldthdIIYMGIS 79
Cdd:TIGR00957 637 ITVHNATFTWarDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS---------VAYVPQQ 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 RTFQNLQLFqamnvfENIYSGliHKYNDSLF-SVFSKSKMNFDKEarekVLEVAEMFDIKNRLTSypsqLTYGMLKRVEM 158
Cdd:TIGR00957 708 AWIQNDSLR------ENILFG--KALNEKYYqQVLEACALLPDLE----ILPSGDRTEIGEKGVN----LSGGQKQRVSL 771
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 159 ARAVISDPDLLLLDEPAAGLNYYETEEI--KSIIQMVNKRGKTILLVEHDMNVVMNVsDLVTVMNfGKKIAEGTP 231
Cdd:TIGR00957 772 ARAVYSNADIYLFDDPLSAVDAHVGKHIfeHVIGPEGVLKNKTRILVTHGISYLPQV-DVIIVMS-GGKISEMGS 844
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
2-205 |
2.82e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 54.15 E-value: 2.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTV--TFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPhKGDILFKGESllkldthdiiymgis 79
Cdd:TIGR01271 1218 MDVQGLTAkyTEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLST-EGEIQIDGVS--------------- 1281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 80 rtFQNLQLFQAMNVFeniysGLIHKyndSLFSVFSKSKMNFDKEAR---EKVLEVAEMFDIKNRLTSYPSQLTY------ 150
Cdd:TIGR01271 1282 --WNSVTLQTWRKAF-----GVIPQ---KVFIFSGTFRKNLDPYEQwsdEEIWKVAEEVGLKSVIEQFPDKLDFvlvdgg 1351
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 151 -----GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGkTILLVEH 205
Cdd:TIGR01271 1352 yvlsnGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTLKQSFSNC-TVILSEH 1410
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
32-206 |
3.46e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 53.80 E-value: 3.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 32 LIGPNGAGKTTLFntitRIVNphkGDILfkgesllkLDTHDIIYMG---ISRTFQNLQLFQAMNVFENIYSGLIH----- 103
Cdd:PRK11147 34 LVGRNGAGKSTLM----KILN---GEVL--------LDDGRIIYEQdliVARLQQDPPRNVEGTVYDFVAEGIEEqaeyl 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 104 -KYNDSLFSVFSK-SKMNFDKEAR-EKVLEVAEMFDIKNRLT-----------SYPSQLTYGMLKRVEMARAVISDPDLL 169
Cdd:PRK11147 99 kRYHDISHLVETDpSEKNLNELAKlQEQLDHHNLWQLENRINevlaqlgldpdAALSSLSGGWLRKAALGRALVSNPDVL 178
|
170 180 190
....*....|....*....|....*....|....*..
gi 1341787947 170 LLDEPAaglNYYETEEIKSIIQMVNKRGKTILLVEHD 206
Cdd:PRK11147 179 LLDEPT---NHLDIETIEWLEGFLKTFQGSIIFISHD 212
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
3-205 |
3.69e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 53.48 E-value: 3.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITrivnphkGD---------ILF-----KGESLLKL 68
Cdd:PRK10938 262 VLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLIT-------GDhpqgysndlTLFgrrrgSGETIWDI 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 69 DTHdIIYMGISrtfqnLQL-----FQAMNVfenIYSGlihkYNDS--LFSVFSkskmnfDKEaREKVLEVAEMFDIKNRL 141
Cdd:PRK10938 335 KKH-IGYVSSS-----LHLdyrvsTSVRNV---ILSG----FFDSigIYQAVS------DRQ-QKLAQQWLDILGIDKRT 394
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 142 TSYPSQ-LTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILL-VEH 205
Cdd:PRK10938 395 ADAPFHsLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLfVSH 460
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
2-205 |
3.89e-08 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 53.71 E-value: 3.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLF-----NTITRIvnPHKGDILFKGESLLKLDT---HDI 73
Cdd:PLN03073 178 IHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLrymamHAIDGI--PKNCQILHVEQEVVGDDTtalQCV 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 74 IYMGISRTF---QNLQLFQAMNVFEniYSGLIHKYNDSLFSVFSKSKMNFDKEAREKVLEVAEMFDIKNRLTSYPSQLTY 150
Cdd:PLN03073 256 LNTDIERTQlleEEAQLVAQQRELE--FETETGKGKGANKDGVDKDAVSQRLEEIYKRLELIDAYTAEARAASILAGLSF 333
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 151 --------------GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQmvnKRGKTILLVEH 205
Cdd:PLN03073 334 tpemqvkatktfsgGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLL---KWPKTFIVVSH 399
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-230 |
4.78e-08 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 53.18 E-value: 4.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNVTVTFGGLKAV-NDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLdTHDIIYMGISR 80
Cdd:PRK10790 341 IDIDNVSFAYRDDNLVlQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSL-SHSVLRQGVAM 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFqAMNVFENIYSGlihkyndslfsvfskskMNFDKEAREKVLEVAEMFD--------IKNRLTSYPSQLTYGM 152
Cdd:PRK10790 420 VQQDPVVL-ADTFLANVTLG-----------------RDISEEQVWQALETVQLAElarslpdgLYTPLGEQGNNLSVGQ 481
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 153 LKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRgKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGT 230
Cdd:PRK10790 482 KQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH-TTLVVIAHRLSTIVE-ADTILVLHRGQAVEQGT 557
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
1-224 |
9.72e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 52.04 E-value: 9.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTfgGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHDIIYMGISr 80
Cdd:PRK10982 250 ILEVRNLTSL--RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAINHGFA- 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 tfqnlqLFQAMNVFENIYSGLIHKYNdSLFSVFSKSKMNF----DKEAREKVLEVAEMFDIKNrltsyPSQ------LTY 150
Cdd:PRK10982 327 ------LVTEERRSTGIYAYLDIGFN-SLISNIRNYKNKVglldNSRMKSDTQWVIDSMRVKT-----PGHrtqigsLSG 394
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 151 GMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVMNFGK 224
Cdd:PRK10982 395 GNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGL 468
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
3-43 |
1.22e-07 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 51.87 E-value: 1.22e-07
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQG-KIhALIGPNGAGKTTL 43
Cdd:PRK11147 321 EMENVNYQIDGKQLVKDFSAQVQRGdKI-ALIGPNGCGKTTL 361
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
28-206 |
1.38e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 51.86 E-value: 1.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 28 KIhALIGPNGAGKTTLFNTITRIvnphkgDILFKGESLLKLdthdiiymGISRTF--QNLQLFQAMNVFENIYSGLIHKY 105
Cdd:TIGR03719 33 KI-GVLGLNGAGKSTLLRIMAGV------DKDFNGEARPQP--------GIKVGYlpQEPQLDPTKTVRENVEEGVAEIK 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 106 N-----DSLFSVFSKSKMNFDKEAREK-----VLEVAEMFDIKNRLT------------SYPSQLTYGMLKRVEMARAVI 163
Cdd:TIGR03719 98 DaldrfNEISAKYAEPDADFDKLAAEQaelqeIIDAADAWDLDSQLEiamdalrcppwdADVTKLSGGERRRVALCRLLL 177
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1341787947 164 SDPDLLLLDEPAaglNYYETEEIKSIIQMVNKRGKTILLVEHD 206
Cdd:TIGR03719 178 SKPDMLLLDEPT---NHLDAESVAWLERHLQEYPGTVVAVTHD 217
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
18-210 |
2.78e-07 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 49.96 E-value: 2.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 18 NDFSITISQGKIHALIGPNGAGKTTLFNTITrivnphkGDILFKGESllklDTHDIiymgisrtfQNLQLFQAMNVFENI 97
Cdd:COG2401 47 RDLNLEIEPGEIVLIVGASGSGKSTLLRLLA-------GALKGTPVA----GCVDV---------PDNQFGREASLIDAI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 98 YSglihkyndslfsvfskskmNFDKEAREKVLEVAEMFDIKNRLTSYpSQLTYGMLKRVEMARAVISDPDLLLLDEPAAG 177
Cdd:COG2401 107 GR-------------------KGDFKDAVELLNAVGLSDAVLWLRRF-KELSTGQKFRFRLALLLAERPKLLVIDEFCSH 166
|
170 180 190
....*....|....*....|....*....|....
gi 1341787947 178 LNYYETEEIKSIIQ-MVNKRGKTILLVEHDMNVV 210
Cdd:COG2401 167 LDRQTAKRVARNLQkLARRAGITLVVATHHYDVI 200
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
24-229 |
5.08e-07 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 50.26 E-value: 5.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 24 ISQGKIHALIGPNGAGKTTLFNTITRIVNPH--KGDILFKGESLLKLdthdiIYMGISRTFQNLQLFQAMNVFENIysgl 101
Cdd:PLN03211 91 ASPGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPTKQ-----ILKRTGFVTQDDILYPHLTVRETL---- 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 102 ihkyndsLFSVFSKSKMNFDKEAREKVLE--VAEMFDIKNRLT----SYPSQLTYGMLKRVEMARAVISDPDLLLLDEPA 175
Cdd:PLN03211 162 -------VFCSLLRLPKSLTKQEKILVAEsvISELGLTKCENTiignSFIRGISGGERKRVSIAHEMLINPSLLILDEPT 234
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 176 AGLNYYETEEIKSIIQMVNKRGKTILLVEHD-MNVVMNVSDLVTVMNFGKKIAEG 229
Cdd:PLN03211 235 SGLDATAAYRLVLTLGSLAQKGKTIVTSMHQpSSRVYQMFDSVLVLSEGRCLFFG 289
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
21-203 |
9.63e-07 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 49.24 E-value: 9.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 21 SITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGD--------ILFKGESLLKLdthdiiymgISRTFQnlqlfqamn 92
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGErqsqfshiTRLSFEQLQKL---------VSDEWQ--------- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 93 vfeniysgliHKYNDSLfsvfSKSKMNFDKEAREKVL----------EVAEMFDIKNRLTSYPSQLTYGMLKRVEMARAV 162
Cdd:PRK10938 85 ----------RNNTDML----SPGEDDTGRTTAEIIQdevkdparceQLAQQFGITALLDRRFKYLSTGETRKTLLCQAL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1341787947 163 ISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLV 203
Cdd:PRK10938 151 MSEPDLLILDEPFDGLDVASRQQLAELLASLHQSGITLVLV 191
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
16-210 |
1.23e-06 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 48.27 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllkldthdiiymgISRTFQNLQLFQAMNVFE 95
Cdd:PRK13546 39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE--------------VSVIAISAGLSGQLTGIE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 96 NIYSGLihkyndsLFSVFSKSKMnfdKEAREKVLEVAEMFD-IKNRLTSYPSqltyGMLKRVEMARAVISDPDLLLLDEP 174
Cdd:PRK13546 105 NIEFKM-------LCMGFKRKEI---KAMTPKIIEFSELGEfIYQPVKKYSS----GMRAKLGFSINITVNPDILVIDEA 170
|
170 180 190
....*....|....*....|....*....|....*.
gi 1341787947 175 AAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVV 210
Cdd:PRK13546 171 LSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQV 206
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
2-58 |
1.46e-06 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 48.73 E-value: 1.46e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 2 LEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDI 58
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV 376
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1-206 |
1.80e-06 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 48.35 E-value: 1.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDI-LFKGESLLKLDTH-------- 71
Cdd:PRK15064 1 MLSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVsLDPNERLGKLRQDqfafeeft 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 72 --DIIYMGisrtfqNLQLFQAMNVFENIYSGLIHKYND-----SLFSVFSKskMN-FDKEAR--EKVLEVAEMFDIKNRL 141
Cdd:PRK15064 81 vlDTVIMG------HTELWEVKQERDRIYALPEMSEEDgmkvaDLEVKFAE--MDgYTAEARagELLLGVGIPEEQHYGL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 142 TSypsQLTYGMLKRVEMARAVISDPDLLLLDEPAaglNYYETEEIKSIIQMVNKRGKTILLVEHD 206
Cdd:PRK15064 153 MS---EVAPGWKLRVLLAQALFSNPDILLLDEPT---NNLDINTIRWLEDVLNERNSTMIIISHD 211
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
148-235 |
1.93e-06 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 48.47 E-value: 1.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAvISDPD----LLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTV---- 219
Cdd:TIGR00630 830 LSGGEAQRIKLAKE-LSKRStgrtLYILDEPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEHNLDVIKTADYIIDLgpeg 908
|
90
....*....|....*..
gi 1341787947 220 -MNFGKKIAEGTPEDIA 235
Cdd:TIGR00630 909 gDGGGTVVASGTPEEVA 925
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
148-219 |
2.07e-06 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 46.80 E-value: 2.07e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1341787947 148 LTYGMLKRVEMARAVISDPDLLLLDEPAAglnYYETEE----IKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTV 219
Cdd:cd03222 72 LSGGELQRVAIAAALLRNATFYLFDEPSA---YLDIEQrlnaARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHV 144
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
146-234 |
4.95e-06 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 47.52 E-value: 4.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 146 SQLTYGMLKRVEMARAVIS---DPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVmNVSDLVTVM-- 220
Cdd:PRK00635 808 SSLSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEHNMHVV-KVADYVLELgp 886
|
90
....*....|....*...
gi 1341787947 221 ---NFGKK-IAEGTPEDI 234
Cdd:PRK00635 887 eggNLGGYlLASCSPEEL 904
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
1-234 |
5.16e-06 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 47.09 E-value: 5.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTV---TFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTI------TRIvnphKGDILFKGESLLKLDTH 71
Cdd:NF040905 257 VFEVKNWTVyhpLHPERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVfgrsygRNI----SGTVFKDGKEVDVSTVS 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 72 DIIYMGIS-----RTFQNLqlfqamNVFENIysglihKYNDSLFSVFSKSKMNFDKEAREkvLEVAEMFDIKNRLTSyPS 146
Cdd:NF040905 333 DAIDAGLAyvtedRKGYGL------NLIDDI------KRNITLANLGKVSRRGVIDENEE--IKVAEEYRKKMNIKT-PS 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 147 ------QLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVSDLVTVM 220
Cdd:NF040905 398 vfqkvgNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVISSELPELLGMCDRIYVM 477
|
250
....*....|....*....
gi 1341787947 221 NFGK-----KIAEGTPEDI 234
Cdd:NF040905 478 NEGRitgelPREEASQERI 496
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
2-60 |
1.34e-05 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 44.07 E-value: 1.34e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 2 LEVKNVTVT--FGGLKaVNDFSITISQGKIHALIGPNGAGKTTLFNTIT--------RIVNPHKGDILF 60
Cdd:cd03223 1 IELENLSLAtpDGRVL-LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAglwpwgsgRIGMPEGEDLLF 68
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
14-239 |
1.40e-05 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 45.28 E-value: 1.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 14 LKAVNDFsitISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESLLKLDTHdIIYMGISRTFQNLQLFqamnv 93
Cdd:cd03288 37 LKHVKAY---IKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLH-TLRSRLSIILQDPILF----- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 94 feniySGLIhkyndslfsvfsksKMNFDKEAR---EKVLEVAEMFDIKNRLTSYPSQL-----------TYGMLKRVEMA 159
Cdd:cd03288 108 -----SGSI--------------RFNLDPECKctdDRLWEALEIAQLKNMVKSLPGGLdavvteggenfSVGQRQLFCLA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 160 RAVISDPDLLLLDEPAAGLNyYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNvSDLVTVMNFGKKIAEGTPEDIANNEE 239
Cdd:cd03288 169 RAFVRKSSILIMDEATASID-MATENILQKVVMTAFADRTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLAQED 246
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
168-239 |
1.79e-05 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 45.45 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 168 LLLLDEPAAGLNyyeTEEIKSIIQMVNK---RGKTILLVEHDMNVVMNvSDLVTVM------NFGKKIAEGTPEDIANNE 238
Cdd:PRK00349 854 LYILDEPTTGLH---FEDIRKLLEVLHRlvdKGNTVVVIEHNLDVIKT-ADWIIDLgpeggdGGGEIVATGTPEEVAKVE 929
|
.
gi 1341787947 239 E 239
Cdd:PRK00349 930 A 930
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
168-239 |
2.19e-05 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 45.40 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 168 LLLLDEPAAGLNYyetEEIKSIIQMVNK---RGKTILLVEHDMNVVmNVSDLVTVM------NFGKKIAEGTPEDIANNE 238
Cdd:COG0178 850 LYILDEPTTGLHF---HDIRKLLEVLHRlvdKGNTVVVIEHNLDVI-KTADWIIDLgpeggdGGGEIVAEGTPEEVAKVK 925
|
.
gi 1341787947 239 E 239
Cdd:COG0178 926 A 926
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
170-237 |
2.20e-05 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 45.20 E-value: 2.20e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 170 LLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVmNVSDLVTVMN-----FGKKIA-EGTPEDIANN 237
Cdd:PRK00635 501 ILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHDEQMI-SLADRIIDIGpgagiFGGEVLfNGSPREFLAK 573
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
16-236 |
2.23e-05 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 45.09 E-value: 2.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 16 AVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGESL--LKLDTHDIIYMGISRT-FqnlqLFQAmN 92
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLtkLQLDSWRSRLAVVSQTpF----LFSD-T 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 93 VFENIYSGlihkyndslfsvfsksKMNFDKEAREKVLEVAEMFDIKNRL-TSYPSQ-------LTYGMLKRVEMARAVIS 164
Cdd:PRK10789 405 VANNIALG----------------RPDATQQEIEHVARLASVHDDILRLpQGYDTEvgergvmLSGGQKQRISIARALLL 468
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1341787947 165 DPDLLLLDEPAAGLNyYETEEikSIIQMVNK--RGKTILLVEHDMNVVMNVSDLVtVMNFGKKIAEGTPEDIAN 236
Cdd:PRK10789 469 NAEILILDDALSAVD-GRTEH--QILHNLRQwgEGRTVIISAHRLSALTEASEIL-VMQHGHIAQRGNHDQLAQ 538
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
7-201 |
2.40e-05 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 43.77 E-value: 2.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 7 VTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTIT--RIVNPHKGDILFKGESLLKldthdiiymgisrTFQn 84
Cdd:cd03232 13 VPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAgrKTAGVITGEILINGRPLDK-------------NFQ- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 85 lqlfqamnvfenIYSGLIHKyNDSLFSVFskskmnfdkeareKVLEvAEMFDIKNRltsypsQLTYGMLKRVEMARAVIS 164
Cdd:cd03232 79 ------------RSTGYVEQ-QDVHSPNL-------------TVRE-ALRFSALLR------GLSVEQRKRLTIGVELAA 125
|
170 180 190
....*....|....*....|....*....|....*..
gi 1341787947 165 DPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTIL 201
Cdd:cd03232 126 KPSILFLDEPTSGLDSQAAYNIVRFLKKLADSGQAIL 162
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
3-179 |
2.42e-05 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 45.22 E-value: 2.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTIT-RIVNPH-KGDILFKGesllkldthdiiYMGISR 80
Cdd:PLN03140 882 EMKEQGVTEDRLQLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAgRKTGGYiEGDIRISG------------FPKKQE 949
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 81 TFQNLQLFQAMNvfeNIYSGLIHKYNDSLFSVF-------SK-SKMNFDKEarekVLEVAEMFDIKNRLTSYP--SQLTY 150
Cdd:PLN03140 950 TFARISGYCEQN---DIHSPQVTVRESLIYSAFlrlpkevSKeEKMMFVDE----VMELVELDNLKDAIVGLPgvTGLST 1022
|
170 180
....*....|....*....|....*....
gi 1341787947 151 GMLKRVEMARAVISDPDLLLLDEPAAGLN 179
Cdd:PLN03140 1023 EQRKRLTIAVELVANPSIIFMDEPTSGLD 1051
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
3-177 |
3.25e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 44.73 E-value: 3.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 3 EVKNVTVTFGGLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTIT--RIVnpHKGDILFKG---------ESLLkldtH 71
Cdd:NF033858 3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAgaRKI--QQGRVEVLGgdmadarhrRAVC----P 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 72 DIIYM--GISRtfqNlqLFQAMNVFENIysglihkynD---SLFSvfskskmnFDKEAREK----VLEVAEMFDIKNRlt 142
Cdd:NF033858 77 RIAYMpqGLGK---N--LYPTLSVFENL---------DffgRLFG--------QDAAERRRrideLLRATGLAPFADR-- 132
|
170 180 190
....*....|....*....|....*....|....*.
gi 1341787947 143 syPS-QLTYGMLKRVEMARAVISDPDLLLLDEPAAG 177
Cdd:NF033858 133 --PAgKLSGGMKQKLGLCCALIHDPDLLILDEPTTG 166
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
24-251 |
8.72e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 43.57 E-value: 8.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 24 ISQGKIHALIGPNGAGKTTLFNTITrivnphkgdilfkGESLLKLDTHDIIYMGISRTFQNLQLFQAmNVFENIYSGLih 103
Cdd:PLN03130 640 VPVGSLVAIVGSTGEGKTSLISAML-------------GELPPRSDASVVIRGTVAYVPQVSWIFNA-TVRDNILFGS-- 703
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 104 kyndslfsvfskskmNFDKEAREKVLEVAEMfdiKNRLTSYPS-----------QLTYGMLKRVEMARAVISDPDLLLLD 172
Cdd:PLN03130 704 ---------------PFDPERYERAIDVTAL---QHDLDLLPGgdlteigergvNISGGQKQRVSMARAVYSNSDVYIFD 765
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1341787947 173 EPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVsDLVTVMNFGKKIAEGTPEDIANNEEVVKVYLgedENA 251
Cdd:PLN03130 766 DPLSALDAHVGRQVFDKCIKDELRGKTRVLVTNQLHFLSQV-DRIILVHEGMIKEEGTYEELSNNGPLFQKLM---ENA 840
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
19-235 |
1.17e-04 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 43.23 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKgesllkldtHDIIYMGisrtfqnlQLFQAMN--VFEN 96
Cdd:PTZ00243 678 DVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAE---------RSIAYVP--------QQAWIMNatVRGN 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 97 IysglihkyndsLFsvfskskmnFDKEAREKVLEVAEMFDIKNRLTSYPS-----------QLTYGMLKRVEMARAVISD 165
Cdd:PTZ00243 741 I-----------LF---------FDEEDAARLADAVRVSQLEADLAQLGGgleteigekgvNLSGGQKARVSLARAVYAN 800
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 166 PDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVmNVSDLVTVMNFGKKIAEGTPEDIA 235
Cdd:PTZ00243 801 RDVYLLDDPLSALDAHVGERVVEECFLGALAGKTRVLATHQVHVV-PRADYVVALGDGRVEFSGSSADFM 869
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
17-251 |
1.49e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 42.66 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 17 VNDFSITISQGKIHALIGPNGAGKTTLFNTITrivnphkgdilfkGESLLKLDTHDIIYMGISRTFQNLQLFQAmNVFEN 96
Cdd:PLN03232 633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAML-------------GELSHAETSSVVIRGSVAYVPQVSWIFNA-TVREN 698
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 97 IYSGlihkyndslfSVFSKSKM--NFDKEAREKVLEVAEMFDIkNRLTSYPSQLTYGMLKRVEMARAVISDPDLLLLDEP 174
Cdd:PLN03232 699 ILFG----------SDFESERYwrAIDVTALQHDLDLLPGRDL-TEIGERGVNISGGQKQRVSMARAVYSNSDIYIFDDP 767
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 175 AAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNVsDLVTVMNFGKKIAEGTPEDIANNEEVVKVYLgedENA 251
Cdd:PLN03232 768 LSALDAHVAHQVFDSCMKDELKGKTRVLVTNQLHFLPLM-DRIILVSEGMIKEEGTFAELSKSGSLFKKLM---ENA 840
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
148-206 |
1.57e-04 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 41.86 E-value: 1.57e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1341787947 148 LTYGMLKRVEMARAVISDPD--LLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHD 206
Cdd:cd03270 138 LSGGEAQRIRLATQIGSGLTgvLYVLDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHD 198
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
1-205 |
1.84e-04 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 42.10 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 1 MLEVKNVTVTFGGLKA-VNDFSITISQGKiHALI-GPNGAGKTTLFNTIT--------RIVNPHKGDILFkgesL----- 65
Cdd:COG4178 362 ALALEDLTLRTPDGRPlLEDLSLSLKPGE-RLLItGPSGSGKSTLLRAIAglwpygsgRIARPAGARVLF----Lpqrpy 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 66 LKLDThdiiymgisrtfqnlqLFQAMnvfenIYSGLIHKYNDslfsvfskskmnfdkEAREKVLEVAEMFDIKNRL---T 142
Cdd:COG4178 437 LPLGT----------------LREAL-----LYPATAEAFSD---------------AELREALEAVGLGHLAERLdeeA 480
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 143 SYPSQLTYGMLKRVEMARAVISDPDLLLLDEPAAGLNyyETEEiKSIIQMVNKR--GKTILLVEH 205
Cdd:COG4178 481 DWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALD--EENE-AALYQLLREElpGTTVISVGH 542
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
148-231 |
2.52e-04 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 41.45 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 148 LTYGMLKRVEMARAvISDPD----LLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVVMNvSDLVTVM--- 220
Cdd:cd03271 170 LSGGEAQRIKLAKE-LSKRStgktLYILDEPTTGLHFHDVKKLLEVLQRLVDKGNTVVVIEHNLDVIKC-ADWIIDLgpe 247
|
90
....*....|....
gi 1341787947 221 ---NFGKKIAEGTP 231
Cdd:cd03271 248 ggdGGGQVVASGTP 261
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
168-239 |
2.99e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 41.92 E-value: 2.99e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1341787947 168 LLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNvVMNVSDLVTVM-----NFGKKI-AEGTPEDIANNEE 239
Cdd:TIGR00630 511 LYVLDEPSIGLHQRDNRRLINTLKRLRDLGNTLIVVEHDED-TIRAADYVIDIgpgagEHGGEVvASGTPEEILANPD 587
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
15-178 |
6.24e-04 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 40.37 E-value: 6.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 15 KAVNDFSITISQGkIHALIGPNGAGKTTLFNTItrivnphkgDILFKGESLLKLDTHD----------------IIYMGI 78
Cdd:COG3593 12 RSIKDLSIELSDD-LTVLVGENNSGKSSILEAL---------RLLLGPSSSRKFDEEDfylgddpdlpeieielTFGSLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 79 SRTFQNL-------QLFQAMNVFENIYSGLIHKYNDSLFSVFSKS------KMNFDKEAREKVLEVAEM-------FDIK 138
Cdd:COG3593 82 SRLLRLLlkeedkeELEEALEELNEELKEALKALNELLSEYLKELldgldlELELSLDELEDLLKSLSLriedgkeLPLD 161
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1341787947 139 NRLTSYPSQLTYGMLKRVEMARAvISDPDLLLLDEPAAGL 178
Cdd:COG3593 162 RLGSGFQRLILLALLSALAELKR-APANPILLIEEPEAHL 200
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2-48 |
7.83e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 40.34 E-value: 7.83e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1341787947 2 LEVKNVTVTFGglKAVNDFSitiSQGKIHALIGPNGAGKTTLFNTIT 48
Cdd:TIGR00618 6 LTLKNFGSYKG--THTIDFT---ALGPIFLICGKTGAGKTTLLDAIT 47
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
19-186 |
8.12e-04 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 39.84 E-value: 8.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 19 DFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHKGDILFKGEsllkldthdiiymgISRTFQNLQLFQAmNVFENIY 98
Cdd:cd03291 55 NINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR--------------ISFSSQFSWIMPG-TIKENII 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 99 SGLihkyndslfsvfskskmNFDKEAREKVLEVAEMfdiKNRLTSYPSQ-----------LTYGMLKRVEMARAVISDPD 167
Cdd:cd03291 120 FGV-----------------SYDEYRYKSVVKACQL---EEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDAD 179
|
170
....*....|....*....
gi 1341787947 168 LLLLDEPAAGLNYYETEEI 186
Cdd:cd03291 180 LYLLDSPFGYLDVFTEKEI 198
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
171-239 |
1.14e-03 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 40.06 E-value: 1.14e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1341787947 171 LDEPAAGLNYYETEE-IKSIIQMVNKrGKTILLVEHDMNVVMNVSDLVTV-----MNFGKKIAEGTPEDIANNEE 239
Cdd:PRK00349 515 LDEPSIGLHQRDNDRlIETLKHLRDL-GNTLIVVEHDEDTIRAADYIVDIgpgagVHGGEVVASGTPEEIMKNPN 588
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
18-55 |
1.16e-03 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 36.42 E-value: 1.16e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1341787947 18 NDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPHK 55
Cdd:pfam13555 13 DGHTIPIDPRGNTLLTGPSGSGKSTLLDAIQTLLVPAK 50
|
|
| COG4185 |
COG4185 |
Predicted ABC-type ATPase or kinase [General function prediction only]; |
28-73 |
2.10e-03 |
|
Predicted ABC-type ATPase or kinase [General function prediction only];
Pssm-ID: 443339 Cd Length: 197 Bit Score: 37.95 E-value: 2.10e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1341787947 28 KIHALIGPNGAGKTTLFNTI-------TRIVNPhkgDILFKGESLLKLDTHDI 73
Cdd:COG4185 5 RLYIIAGPNGAGKSTFARTIlpeelggLEFVNA---DLIARGLSPFNPETAAY 54
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
5-75 |
2.45e-03 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 38.01 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 5 KNVTVTFG----GLKAVNDFSITISQGKIHALIGPNGAGKTTLFNTITRIVNPH---KGDILFKGESLLKLD---THDII 74
Cdd:cd03233 7 RNISFTTGkgrsKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAekyPGEII 86
|
.
gi 1341787947 75 Y 75
Cdd:cd03233 87 Y 87
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
57-210 |
2.70e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 38.52 E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 57 DILFKGESLLKLDTHDIIYMGISRTFQNLQLFQAMNVFENIYSGLIHKYNDSLFSVFSKSKMNFDKEAREKVLEVaEMFD 136
Cdd:pfam13304 147 IISPLSFLLLLDEGLLLEDWAVLDLAADLALFPDLKELLQRLVRGLKLADLNLSDLGEGIEKSLLVDDRLRERGL-ILLE 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 137 IKNRLTSYPSQLTYGMLKrveMARAVIS------DPDLLLLDEPAAGLNYYETEEIKSIIQMVNKRGKTILLVEHDMNVV 210
Cdd:pfam13304 226 NGGGGELPAFELSDGTKR---LLALLAAllsalpKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTHSPLLL 302
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
2-109 |
2.93e-03 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 38.06 E-value: 2.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 2 LEVKNvtvtFGGLKavnDFSITIS-QGKIHALIGPNGAGKTTLFNTI--------TRIVNPHKGDILFKGESLLKlDTHD 72
Cdd:COG3950 6 LTIEN----FRGFE---DLEIDFDnPPRLTVLVGENGSGKTTLLEAIalalsgllSRLDDVKFRKLLIRNGEFGD-SAKL 77
|
90 100 110
....*....|....*....|....*....|....*..
gi 1341787947 73 IIYMGISRTFQNLQLFQAMNVFENIYSGLiHKYNDSL 109
Cdd:COG3950 78 ILYYGTSRLLLDGPLKKLERLKEEYFSRL-DGYDSLL 113
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
1-44 |
4.16e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 37.99 E-value: 4.16e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1341787947 1 MLEvknvTVTFGGLKAVNDFSITIsqGKIHALIGPNGAGKTTLF 44
Cdd:COG4637 1 MIT----RIRIKNFKSLRDLELPL--GPLTVLIGANGSGKSNLL 38
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
30-92 |
4.68e-03 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 36.43 E-value: 4.68e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1341787947 30 HALI-GPNGAGKTTLFNTITRIVNPHKGDIL---FKGESLLKLDTHDIIYMGISRTFQNlQLFQAMN 92
Cdd:cd01127 1 NTLVlGTTGSGKTTSIVIPLLDQAARGGSVIitdPKGELFLVIPDRDDSFAALRALFFN-QLFRALT 66
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-48 |
5.16e-03 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 36.91 E-value: 5.16e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1341787947 2 LEVKNvtvtFGGLKAVNdfSITISQGkIHALIGPNGAGKTTLFNTIT 48
Cdd:COG0419 5 LRLEN----FRSYRDTE--TIDFDDG-LNLIVGPNGAGKSTILEAIR 44
|
|
| FlhF |
COG1419 |
Flagellar biosynthesis GTPase FlhF [Cell motility]; |
24-50 |
6.57e-03 |
|
Flagellar biosynthesis GTPase FlhF [Cell motility];
Pssm-ID: 441029 [Multi-domain] Cd Length: 361 Bit Score: 37.15 E-value: 6.57e-03
10 20
....*....|....*....|....*..
gi 1341787947 24 ISQGKIHALIGPNGAGKTTlfnTITRI 50
Cdd:COG1419 161 LDEGGVIALVGPTGVGKTT---TIAKL 184
|
|
| AAA_23 |
pfam13476 |
AAA domain; |
13-119 |
6.88e-03 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 36.71 E-value: 6.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1341787947 13 GLKAVNDFSITISQGkIHALIGPNGAGKTTLFNTIT-------RIVNPHKGDILFKGESLLKLDTHDIIYMGISRTFQNL 85
Cdd:pfam13476 5 NFRSFRDQTIDFSKG-LTLITGPNGSGKTTILDAIKlalygktSRLKRKSGGGFVKGDIRIGLEGKGKAYVEITFENNDG 83
|
90 100 110
....*....|....*....|....*....|....
gi 1341787947 86 QLFQAMNVFENIYSGLIHKYNDSLFSVFSKSKMN 119
Cdd:pfam13476 84 RYTYAIERSRELSKKKGKTKKKEILEILEIDELQ 117
|
|
| |
