|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15083 |
PRK15083 |
PTS system mannitol-specific transporter subunit IICBA; Provisional |
1-648 |
0e+00 |
|
PTS system mannitol-specific transporter subunit IICBA; Provisional
Pssm-ID: 237905 [Multi-domain] Cd Length: 639 Bit Score: 1217.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 1 MVTSNIKLKVQNFGRFLSNMVMPNIGAFIAWGLITALFIPTGWWPNETLAQLVGPMITYLLPLLIGYTGGRLVGGERGGI 80
Cdd:PRK15083 1 MMSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 81 VGAITTMGVIVGADMPMFMGAMIAGPLGGYAIKRFDLWIEGKVKTGFEMLVNNFSSGIIGMLLAILAYLAIGPLVAGLSK 160
Cdd:PRK15083 81 VGAITTMGVIVGADMPMFLGAMIAGPLGGWAIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 161 ILAAGVNVMVENNLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQATETGASIFFLIEANPGPGLGVLLAYMFFGKGNA 240
Cdd:PRK15083 161 MLAAGVNFMVVHDLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 241 KQSAPGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFVMNLFHAGLVSPASPGSIFAVLLMTPKSSLVGVILSV 320
Cdd:PRK15083 241 KQSAGGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTLLNGGLVSPASPGSILAVLAMTPKGAYFANIASV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 321 TSATLVSFIVSAILLKKTRIGDDDELENATKKMRNMKSQSKsSAAVEINQNTSVNLAEVRNIIVACDAGMGSSAMGAGVL 400
Cdd:PRK15083 321 AAAMAVSFVVSAILLKTSKVKEEDDLEAATRRMQDMKAESK-GASPLAAGDVTNDLSHVRKIIVACDAGMGSSAMGAGVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 401 AKKVRDAGLLGISVSNMAINDLPDNVDIVITHKDLTQRAKTFAPNAMHISLTNFLDSQTYNDLVTNLIAKKNPKAANdgr 480
Cdd:PRK15083 400 RKKVQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQRHTENE--- 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 481 likQTIIAANDESYemEDHDDAIFTLSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESI 560
Cdd:PRK15083 477 ---EKVKDSLKDSF--EDSSANLFKLGAENIFLGLKAATKEEAIRFAGEQLVKGGYVEPEYVDAMLDREKLTSTYLGESI 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 561 AVPHGTIEAKDRVLKTGIVICQYPEGVQFGEEPDEIARLVIGIAAQNNEHIEVITRITSALDEDGVIERLCETQDVQEVL 640
Cdd:PRK15083 552 AVPHGTVEAKDRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVL 631
|
....*...
gi 1252954522 641 EILASQSA 648
Cdd:PRK15083 632 ELLAGKKA 639
|
|
| MtlA |
COG2213 |
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and ... |
1-474 |
0e+00 |
|
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism];
Pssm-ID: 441815 [Multi-domain] Cd Length: 479 Bit Score: 856.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 1 MVTSNIKLKVQNFGRFLSNMVMPNIGAFIAWGLITALFIPTGWWPNETLAQLVGPMITYLLPLLIGYTGGRLVGGERGGI 80
Cdd:COG2213 4 MKKGSARAKVQKFGRFLSGMVMPNIGAFIAWGLITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKMVYGVRGGV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 81 VGAITTMGVIVGADMPMFMGAMIAGPLGGYAIKRFDLWIEGKVKTGFEMLVNNFSSGIIGMLLAILAYLAIGPLVAGLSK 160
Cdd:COG2213 84 VGAIATMGVIVGADIPMFLGAMIMGPLGGWVIKKFDKLIEGKIKAGFEMLVNNFSAGILGMLLAILAFFAIGPVVEGLSN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 161 ILAAGVNVMVENNLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQATETGASIFFLIEANPGPGLGVLLAYMFFGKGNA 240
Cdd:COG2213 164 ALAAGVEWLVNAGLLPLASIFIEPAKVLFLNNAINHGILTPLGIQQAAETGKSILFLLEANPGPGLGILLAYMFFGKGSA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 241 KQSAPGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFVMNLFHAGLVSPASPGSIFAVLLMTPKSSLVGVILSV 320
Cdd:COG2213 244 KQSAPGAIIIHFFGGIHEIYFPYVLMKPLLILAVIAGGMTGVFTFVLFGAGLVAPASPGSIFAVLAMTPKGSYLGVILGV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 321 TSATLVSFIVSAILLKKTR-IGDDDELENATKKMRNMKSQSKS--SAAVEINQNTSVNLAEVRNIIVACDAGMGSSAMGA 397
Cdd:COG2213 324 LVAAAVSFLVASIILKRSKsKEDEDDLEAATAKMEAMKGKSSSvaSALTAAAAVGAADASNVKKIVFACDAGMGSSAMGA 403
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1252954522 398 GVLAKKVRDAGlLGISVSNMAINDLPDNVDIVITHKDLTQRAKTFAPNAMHISLTNFLDSQTYNDLVTNLIAKKNPK 474
Cdd:COG2213 404 SVLRKKVKKAG-LDIEVTNTAINNLPDDADLVITHKDLTERAKQKAPNAQHISVDNFLNSPKYDELVEKLKKQNDDS 479
|
|
| mtlA |
TIGR00851 |
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and ... |
9-346 |
0e+00 |
|
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities.The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This family is specific for the IIC domain of the mannitol PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 129930 Cd Length: 338 Bit Score: 518.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 9 KVQNFGRFLSNMVMPNIGAFIAWGLITALFIPTGWWPNETLAQLVGPMITYLLPLLIGYTGGRLVGGERGGIVGAITTMG 88
Cdd:TIGR00851 1 KVQRFGSFLSGMIMPNIGAFIAWGIITALFIPTGWFPNETLAKLVGPMITYLLPLLIAYTGGKLIYDLRGGVVGATATMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 89 VIVGADMPMFMGAMIAGPLGGYAIKRFDLWIEGKVKTGFEMLVNNFSSGIIGMLLAILAYLAIGPLVAGLSKILAAGVNV 168
Cdd:TIGR00851 81 VIVGSDIPMFLGAMIMGPLGGWLIKKTDEFVQGKVKQGFEMLVNNFSAGIIGFILTILAFEGIGPIVKAISKILAAGVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 169 MVENNLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQATETGASIFFLIEANPGPGLGVLLAYMFFGKGNAKQSAPGAA 248
Cdd:TIGR00851 161 IVHAHLLPLASIFVEPAKILFLNNAINHGIFSPLGIEQAAHTGKSILFLIEANPGPGLGVLLAYMFFGKGSAKQTAPGAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 249 IIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFVMNLFHAGLVSPASPGSIFAVLLMTPKSSLVGVILSVTSATLVSF 328
Cdd:TIGR00851 241 IIHFFGGIHEIYFPYVLMRPLLILAVILGGMTGVLTYTILDAGLVAPASPGSIIALLAMTPKGEYLGVLAGVLVAAAVSF 320
|
330
....*....|....*...
gi 1252954522 329 IVSAILLKKTRIGDDDEL 346
Cdd:TIGR00851 321 VVSAIILKSSKDPEEDLI 338
|
|
| PTS_IIA_fru |
cd00211 |
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ... |
506-643 |
2.04e-42 |
|
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.
Pssm-ID: 238129 [Multi-domain] Cd Length: 136 Bit Score: 149.63 E-value: 2.04e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 506 LSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAkdrVLKTGIVICQYPE 585
Cdd:cd00211 1 LTKENIRLNLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLEREKEGSTGIGNGIAIPHAKSEA---VKKPGIAVLRLKE 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1252954522 586 GVQFGEEPDEIARLVIGIAAQN-NEHIEVITRITSALDEDGVIERLCETQDVQEVLEIL 643
Cdd:cd00211 78 PVDFGSLDGQPVHLIFLLAAPDsNEHLKALSQLARLLSDEEFVEQLLNAQSKEEILALL 136
|
|
| PTS_EIIA_2 |
pfam00359 |
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; |
506-644 |
2.44e-35 |
|
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
Pssm-ID: 459780 [Multi-domain] Cd Length: 139 Bit Score: 130.02 E-value: 2.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 506 LSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAkdrVLKTGIVICQYPE 585
Cdd:pfam00359 2 LDKELIFLNLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILEREKEGSTGIGNGIAIPHARSEA---VKKPGIAVLTLKE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1252954522 586 GVQFGEEPDEIARLVIGIAAQNNE--HIEVITRITSALDEDGVIERLCETQDVQEVLEILA 644
Cdd:pfam00359 79 PVDFGSEDGKPVKLIFLLAAPDNEasHLKILSQLARLLQDEEFVEKLLKAKDPEEILEILK 139
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15083 |
PRK15083 |
PTS system mannitol-specific transporter subunit IICBA; Provisional |
1-648 |
0e+00 |
|
PTS system mannitol-specific transporter subunit IICBA; Provisional
Pssm-ID: 237905 [Multi-domain] Cd Length: 639 Bit Score: 1217.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 1 MVTSNIKLKVQNFGRFLSNMVMPNIGAFIAWGLITALFIPTGWWPNETLAQLVGPMITYLLPLLIGYTGGRLVGGERGGI 80
Cdd:PRK15083 1 MMSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 81 VGAITTMGVIVGADMPMFMGAMIAGPLGGYAIKRFDLWIEGKVKTGFEMLVNNFSSGIIGMLLAILAYLAIGPLVAGLSK 160
Cdd:PRK15083 81 VGAITTMGVIVGADMPMFLGAMIAGPLGGWAIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 161 ILAAGVNVMVENNLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQATETGASIFFLIEANPGPGLGVLLAYMFFGKGNA 240
Cdd:PRK15083 161 MLAAGVNFMVVHDLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 241 KQSAPGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFVMNLFHAGLVSPASPGSIFAVLLMTPKSSLVGVILSV 320
Cdd:PRK15083 241 KQSAGGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTLLNGGLVSPASPGSILAVLAMTPKGAYFANIASV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 321 TSATLVSFIVSAILLKKTRIGDDDELENATKKMRNMKSQSKsSAAVEINQNTSVNLAEVRNIIVACDAGMGSSAMGAGVL 400
Cdd:PRK15083 321 AAAMAVSFVVSAILLKTSKVKEEDDLEAATRRMQDMKAESK-GASPLAAGDVTNDLSHVRKIIVACDAGMGSSAMGAGVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 401 AKKVRDAGLLGISVSNMAINDLPDNVDIVITHKDLTQRAKTFAPNAMHISLTNFLDSQTYNDLVTNLIAKKNPKAANdgr 480
Cdd:PRK15083 400 RKKVQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQRHTENE--- 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 481 likQTIIAANDESYemEDHDDAIFTLSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESI 560
Cdd:PRK15083 477 ---EKVKDSLKDSF--EDSSANLFKLGAENIFLGLKAATKEEAIRFAGEQLVKGGYVEPEYVDAMLDREKLTSTYLGESI 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 561 AVPHGTIEAKDRVLKTGIVICQYPEGVQFGEEPDEIARLVIGIAAQNNEHIEVITRITSALDEDGVIERLCETQDVQEVL 640
Cdd:PRK15083 552 AVPHGTVEAKDRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVL 631
|
....*...
gi 1252954522 641 EILASQSA 648
Cdd:PRK15083 632 ELLAGKKA 639
|
|
| MtlA |
COG2213 |
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and ... |
1-474 |
0e+00 |
|
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism];
Pssm-ID: 441815 [Multi-domain] Cd Length: 479 Bit Score: 856.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 1 MVTSNIKLKVQNFGRFLSNMVMPNIGAFIAWGLITALFIPTGWWPNETLAQLVGPMITYLLPLLIGYTGGRLVGGERGGI 80
Cdd:COG2213 4 MKKGSARAKVQKFGRFLSGMVMPNIGAFIAWGLITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKMVYGVRGGV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 81 VGAITTMGVIVGADMPMFMGAMIAGPLGGYAIKRFDLWIEGKVKTGFEMLVNNFSSGIIGMLLAILAYLAIGPLVAGLSK 160
Cdd:COG2213 84 VGAIATMGVIVGADIPMFLGAMIMGPLGGWVIKKFDKLIEGKIKAGFEMLVNNFSAGILGMLLAILAFFAIGPVVEGLSN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 161 ILAAGVNVMVENNLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQATETGASIFFLIEANPGPGLGVLLAYMFFGKGNA 240
Cdd:COG2213 164 ALAAGVEWLVNAGLLPLASIFIEPAKVLFLNNAINHGILTPLGIQQAAETGKSILFLLEANPGPGLGILLAYMFFGKGSA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 241 KQSAPGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFVMNLFHAGLVSPASPGSIFAVLLMTPKSSLVGVILSV 320
Cdd:COG2213 244 KQSAPGAIIIHFFGGIHEIYFPYVLMKPLLILAVIAGGMTGVFTFVLFGAGLVAPASPGSIFAVLAMTPKGSYLGVILGV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 321 TSATLVSFIVSAILLKKTR-IGDDDELENATKKMRNMKSQSKS--SAAVEINQNTSVNLAEVRNIIVACDAGMGSSAMGA 397
Cdd:COG2213 324 LVAAAVSFLVASIILKRSKsKEDEDDLEAATAKMEAMKGKSSSvaSALTAAAAVGAADASNVKKIVFACDAGMGSSAMGA 403
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1252954522 398 GVLAKKVRDAGlLGISVSNMAINDLPDNVDIVITHKDLTQRAKTFAPNAMHISLTNFLDSQTYNDLVTNLIAKKNPK 474
Cdd:COG2213 404 SVLRKKVKKAG-LDIEVTNTAINNLPDDADLVITHKDLTERAKQKAPNAQHISVDNFLNSPKYDELVEKLKKQNDDS 479
|
|
| mtlA |
TIGR00851 |
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and ... |
9-346 |
0e+00 |
|
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities.The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This family is specific for the IIC domain of the mannitol PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 129930 Cd Length: 338 Bit Score: 518.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 9 KVQNFGRFLSNMVMPNIGAFIAWGLITALFIPTGWWPNETLAQLVGPMITYLLPLLIGYTGGRLVGGERGGIVGAITTMG 88
Cdd:TIGR00851 1 KVQRFGSFLSGMIMPNIGAFIAWGIITALFIPTGWFPNETLAKLVGPMITYLLPLLIAYTGGKLIYDLRGGVVGATATMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 89 VIVGADMPMFMGAMIAGPLGGYAIKRFDLWIEGKVKTGFEMLVNNFSSGIIGMLLAILAYLAIGPLVAGLSKILAAGVNV 168
Cdd:TIGR00851 81 VIVGSDIPMFLGAMIMGPLGGWLIKKTDEFVQGKVKQGFEMLVNNFSAGIIGFILTILAFEGIGPIVKAISKILAAGVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 169 MVENNLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQATETGASIFFLIEANPGPGLGVLLAYMFFGKGNAKQSAPGAA 248
Cdd:TIGR00851 161 IVHAHLLPLASIFVEPAKILFLNNAINHGIFSPLGIEQAAHTGKSILFLIEANPGPGLGVLLAYMFFGKGSAKQTAPGAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 249 IIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFVMNLFHAGLVSPASPGSIFAVLLMTPKSSLVGVILSVTSATLVSF 328
Cdd:TIGR00851 241 IIHFFGGIHEIYFPYVLMRPLLILAVILGGMTGVLTYTILDAGLVAPASPGSIIALLAMTPKGEYLGVLAGVLVAAAVSF 320
|
330
....*....|....*...
gi 1252954522 329 IVSAILLKKTRIGDDDEL 346
Cdd:TIGR00851 321 VVSAIILKSSKDPEEDLI 338
|
|
| MtlA2 |
COG4668 |
Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and ... |
504-646 |
3.50e-63 |
|
Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism];
Pssm-ID: 443705 [Multi-domain] Cd Length: 143 Bit Score: 205.39 E-value: 3.50e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 504 FTLSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAKDRVLKTGIVICQY 583
Cdd:COG4668 2 LILTKENIRLNASAANKEEAIRLAGQLLVEAGYVEPEYIDAMLEREAQVSTYLGNGIAIPHGTNEAKDLVLKTGISVLQF 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1252954522 584 PEGVQFGEepDEIARLVIGIAAQNNEHIEVITRITSALDEDGVIERLCETQDVQEVLEILASQ 646
Cdd:COG4668 82 PDGVDWGD--GNTVYLVIGIAAKSDEHLEILRQLARVLSDEENVEKLAKATDAEEILALLTGE 142
|
|
| PTS_IIA_fru |
cd00211 |
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ... |
506-643 |
2.04e-42 |
|
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.
Pssm-ID: 238129 [Multi-domain] Cd Length: 136 Bit Score: 149.63 E-value: 2.04e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 506 LSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAkdrVLKTGIVICQYPE 585
Cdd:cd00211 1 LTKENIRLNLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLEREKEGSTGIGNGIAIPHAKSEA---VKKPGIAVLRLKE 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1252954522 586 GVQFGEEPDEIARLVIGIAAQN-NEHIEVITRITSALDEDGVIERLCETQDVQEVLEIL 643
Cdd:cd00211 78 PVDFGSLDGQPVHLIFLLAAPDsNEHLKALSQLARLLSDEEFVEQLLNAQSKEEILALL 136
|
|
| PRK11109 |
PRK11109 |
fused PTS fructose transporter subunit IIA/HPr protein; |
504-649 |
4.02e-38 |
|
fused PTS fructose transporter subunit IIA/HPr protein;
Pssm-ID: 236849 [Multi-domain] Cd Length: 375 Bit Score: 145.48 E-value: 4.02e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 504 FTLSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAKDRVLKTGIVICQY 583
Cdd:PRK11109 2 FQLSVQDIHLGQQAGNKEEAIRQVAAALTQAGNVAEGYVDGMLAREQQTSTFLGNGIAIPHGTTDTRDLVLKTGVQVFQF 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1252954522 584 PEGVQFGEepDEIARLVIGIAAQNNEHIEVITRITSALDEDGVIERLCETQDVQEVLEIL--ASQSAA 649
Cdd:PRK11109 82 PQGVTWGD--GQTAYVAIGIAAKSDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLmgEKQSEQ 147
|
|
| PTS_EIIA_2 |
pfam00359 |
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; |
506-644 |
2.44e-35 |
|
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
Pssm-ID: 459780 [Multi-domain] Cd Length: 139 Bit Score: 130.02 E-value: 2.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 506 LSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAkdrVLKTGIVICQYPE 585
Cdd:pfam00359 2 LDKELIFLNLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILEREKEGSTGIGNGIAIPHARSEA---VKKPGIAVLTLKE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1252954522 586 GVQFGEEPDEIARLVIGIAAQNNE--HIEVITRITSALDEDGVIERLCETQDVQEVLEILA 644
Cdd:pfam00359 79 PVDFGSEDGKPVKLIFLLAAPDNEasHLKILSQLARLLQDEEFVEKLLKAKDPEEILEILK 139
|
|
| PRK13779 |
PRK13779 |
bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional |
503-643 |
8.53e-35 |
|
bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional
Pssm-ID: 237502 [Multi-domain] Cd Length: 503 Bit Score: 138.47 E-value: 8.53e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 503 IFTLSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAKDRVLKTGIVICQ 582
Cdd:PRK13779 1 MLNLSESNIHLNAQAINKQQAIEMAAAALEQAGNVENGYLQGMLARELQTSTFLGNGIAIPHGTLDTRHMVKNTGVQIFQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1252954522 583 YPEGVQFGEepDEIARLVIGIAAQNNEHIEVITRITSALDEDGVIERLCETQDVQEVLEIL 643
Cdd:PRK13779 81 FPQGIEWGE--GNIAYVVIGIAARSDEHLSLLRQLTHVLSDEDTAAKLATLTDVKEFRAIL 139
|
|
| PtsN |
COG1762 |
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ... |
506-645 |
1.91e-34 |
|
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 441368 [Multi-domain] Cd Length: 150 Bit Score: 128.04 E-value: 1.91e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 506 LSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYV--EPDYIEAMLAREKLTSTYLGESIAVPHGTIEAkdrVLKTGIVICQY 583
Cdd:COG1762 7 LTPELILLDLEASSKEEAIEELAELLAEKGYVldKEEYLEALLEREELGSTGIGPGIAIPHARPEG---VKKPGIAVARL 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1252954522 584 PEGVQFGEEPDEIARLVIGIAA---QNNEHIEVITRITSALDEDGVIERLCETQDVQEVLEILAS 645
Cdd:COG1762 84 KEPVDFGAMDGEPVDLVFLLAApedDSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
|
|
| PTS_IIB_mannitol |
cd05567 |
PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate: ... |
380-464 |
2.93e-33 |
|
PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. The IIA, IIB, and IIC domains are expressed from the mtlA gene as a single protein, also known as the mannitol PTS permease, the mtl transporter, or MtlA. MtlA is only functional as a dimer with the dimer contacts occuring between the IIC domains. MtlA takes up exogenous mannitol releasing the phosphate ester into the cytoplasm in preparation for oxidation to fructose-6-phosphate by the NAD-dependent mannitol-P dehydrogenase (MtlD). The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include mannitol, chitobiose/lichenan, ascorbate, lactose, galactitol, fructose, and a sensory system with similarity to the bacterial bgl system.
Pssm-ID: 99909 [Multi-domain] Cd Length: 87 Bit Score: 122.29 E-value: 2.93e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 380 RNIIVACDAGMGSSAMGAGVLAKKVRDAGLlGISVSNMAINDLPDNVDIVITHKDLTQRAKTFAPNAMHISLTNFLDSQT 459
Cdd:cd05567 1 KKIVFACDAGMGSSAMGASVLRKKLKKAGL-EIPVTNSAIDELPSDADLVVTHASLTDRAKKKAPQAQHLSVDNFLNTPE 79
|
....*
gi 1252954522 460 YNDLV 464
Cdd:cd05567 80 YDELI 84
|
|
| PTS_EIIC |
pfam02378 |
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ... |
18-277 |
1.40e-21 |
|
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.
Pssm-ID: 367061 Cd Length: 315 Bit Score: 95.88 E-value: 1.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 18 SNMVMPNIGAFIAWGLITAL------------FIPTGWWPNETLAQLVGPMITYLLPLLIGYTGGRLVGGERGGIVGAIT 85
Cdd:pfam02378 1 GDGFMPPIPLLIAGGILLGLgnlpndttglpaGGFTGDSPLAEILKQAGSAAFGILPILFAIGIAYGLAGGDGVAGAAGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 86 TMGVIVGADMPM------------------------FMGAMIAGPLGGYAIKRFDLWIEGKVKTGFEMLVnnfSSGIIGM 141
Cdd:pfam02378 81 IGLLSFNLAAAIsvaltaaglsgggnilgiglgatgVFGAIIPGLLAAYLYNRFEKNITIKLPDSLPFFV---GKRFVPI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 142 LLAILAYLAIGPLVAGLSKILAAGVNVMVEnnllpltSIFVEPAKILFLNNAINHGIFSPLGIQQA-----TETGASIFF 216
Cdd:pfam02378 158 ITGFVTLLVIGPVLGLIWPAIQGGLNALGL-------LLIIAGGILGGLIFGFLERLLWPFGLHGAfiaifWFLPIGGSN 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 217 LIE---------------------ANPGPGLGVLLAYMFFGKGNAKQSAPGAAIIHFFGGIHEIY---FPYVLMNPRLIL 272
Cdd:pfam02378 231 PIAnqqaygagaahiltggfdvmfGGPGATLALYAAAFLFKKSKVKKLLGSAALTPFLFGITEPLefgFPFVLNPPFFIP 310
|
....*
gi 1252954522 273 AVILG 277
Cdd:pfam02378 311 AILAG 315
|
|
| fruA |
TIGR00848 |
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family ... |
506-630 |
1.52e-17 |
|
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 273298 [Multi-domain] Cd Length: 129 Bit Score: 79.24 E-value: 1.52e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 506 LSAKHIHLNLSAQNKMQAIQFAGQKLVEGGYVE--PDYIEAMLAREKLTSTYLGESIAVPHGTIEAkdrVLKTGIVICQY 583
Cdd:TIGR00848 2 LNKDLIFLDQQFTSKEDVIKFLANKLLENGYISdtEEFLEDLLKREEEGTTGIGDGVAIPHAKSAA---VKQPFVAIARL 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1252954522 584 PEGVQFGEEPDEIARLVIGIAA----QNNEHIEVITRITSALDEDGVIERL 630
Cdd:TIGR00848 79 VKGVDWQSLDGKPVKLIFLIAVpkdeAGNTHLKALSQLARLLLNDEFRAKL 129
|
|
| PRK09765 |
PRK09765 |
PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional |
511-646 |
1.75e-11 |
|
PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional
Pssm-ID: 182066 [Multi-domain] Cd Length: 631 Bit Score: 67.07 E-value: 1.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 511 IHLNLSAQNKMQAIQFAGQKLVEGG--YVEPDYIEAMLAREKLTSTYLGESIAVPHGTIEAkdrVLKTGIVICQYPEGVQ 588
Cdd:PRK09765 12 LCLNARFTSREEAIHALAQRLAALGkiSSTEQFLEEVYRRESLGPTALGEGLAVPHGKTAA---VKEAAFAVATLSEPLQ 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1252954522 589 F-GEEPDEIARLVIGIAAQNNE----HIEVITRITSALDEDGVIERLCETQDVQEVLEILASQ 646
Cdd:PRK09765 89 WeGVDGPEAVDLIFLLAIPPNEagttHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDK 151
|
|
| cmtB |
PRK09854 |
PTS mannitol transporter subunit IIA; |
516-644 |
9.26e-11 |
|
PTS mannitol transporter subunit IIA;
Pssm-ID: 182114 [Multi-domain] Cd Length: 147 Bit Score: 60.39 E-value: 9.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 516 SAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTY--LGESIAVPHGTIEAKdrVLKTGIVICQYPEGVQFGEEP 593
Cdd:PRK09854 17 SAKDWQEAIDFSMVSLLDKNYISENYIQAIKDSTINNGPYyiLAPGVAMPHARPECG--ALKTGMSLTLLEQGVYFPGND 94
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1252954522 594 DEIaRLVIGI-AAQNNEHIEVITRITSALDEDGVIERLCETQDVQEVLEILA 644
Cdd:PRK09854 95 EPI-KLLIGLsAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIIS 145
|
|
| PRK10372 |
PRK10372 |
PTS ascorbate transporter subunit IIA; |
509-649 |
6.59e-10 |
|
PTS ascorbate transporter subunit IIA;
Pssm-ID: 182417 [Multi-domain] Cd Length: 154 Bit Score: 58.06 E-value: 6.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 509 KHIHLNLSAQNKMQAIQFAGQKLVEGGYVEPDYIEAMLAREKLTSTY--LGESIAVPHGTIEakDRVLKTGIVICQYPEG 586
Cdd:PRK10372 11 KSIRLQAEAETWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYfvIAPGLAMPHGRPE--EGVKKTGFALVTLKKP 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1252954522 587 VQFGEEPDEIARLVIGIAAQN-NEHIEV-ITRITSALDEDGVIERLCETQDVQEVLEILASQSAA 649
Cdd:PRK10372 89 LEFNHEDNDPVDILITMAAVDaNTHQEVgIMQIVNLFEDEANFDRLRACRTEQEVLDLIDRTNAA 153
|
|
| nitro_reg_IIA |
TIGR01419 |
PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of ... |
514-630 |
2.60e-09 |
|
PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of about 160 residues closely related to the fructose-specific phosphotransferase (PTS) system IIA component. It is a regulatory protein found only in species with a phosphoenolpyruvate-protein phosphotransferase (enzyme I of PTS systems) and an HPr-like phosphocarrier protein, but not all species have a IIC-like permease. Members of this family are found in Proteobacteria, Chlamydia, and the spirochete Treponema pallidum. [Signal transduction, PTS]
Pssm-ID: 162350 [Multi-domain] Cd Length: 145 Bit Score: 56.27 E-value: 2.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 514 NLSAQNKMQAIQFAGQkLVEGGYVEP--DYIEAMLAREKLTSTYLGESIAVPHGTIEAKDRVlkTGIVIcQYPEGVQFGE 591
Cdd:TIGR01419 14 AMECGSKKRLLEIISL-LAARELSLPeqDVFECLLAREKLGSTGVGNGIAIPHGRLSGLKQP--VGVFI-RLDAPVDFDA 89
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1252954522 592 EPDEIARLVIGI---AAQNNEHIEVITRITSALDEDGVIERL 630
Cdd:TIGR01419 90 LDGKPVDLLFALlvpENATAEHLEALSRIARKLSDKTICRRL 131
|
|
| PTS_IIB |
pfam02302 |
PTS system, Lactose/Cellobiose specific IIB subunit; The bacterial phosphoenolpyruvate: sugar ... |
381-456 |
2.43e-07 |
|
PTS system, Lactose/Cellobiose specific IIB subunit; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes. The fold of IIB cellobiose shows similar structure to mammalian tyrosine phosphatases. This family also contains the fructose specific IIB subunit.
Pssm-ID: 396744 Cd Length: 92 Bit Score: 48.87 E-value: 2.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 381 NIIVACDAGMGSSAMGAGVLAKKVRDAGLL---GISVSNMA-INDLPDNVDIVITHKDLT--QRAKTFAPNAMHISLTNF 454
Cdd:pfam02302 1 KILTACGAGMATSLMAAEALEKAAKELGIVeaqGAAGVNELtAEDIADDADVVILAPDVAveDLARFAGKPVYVIPVKDA 80
|
..
gi 1252954522 455 LD 456
Cdd:pfam02302 81 LG 82
|
|
| PTS_IIB |
cd00133 |
PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the ... |
381-463 |
1.60e-06 |
|
PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system. The PTS is found only in bacteria, where it catalyzes the transport and phosphorylation of numerous monosaccharides, disaccharides, polyols, amino sugars, and other sugar derivatives. The four proteins (domains) forming the PTS phosphorylation cascade (EI, HPr, EIIA, and EIIB), can phosphorylate or interact with numerous non-PTS proteins thereby regulating their activity.
Pssm-ID: 99904 Cd Length: 84 Bit Score: 46.48 E-value: 1.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 381 NIIVACDAGMGSSAMGAGVLAKKVRDAGLLG-ISVSNMAINDLPDNVDIVITHKDLTQRAKtfapNAMHISLTNFLDSQT 459
Cdd:cd00133 1 KILVVCGSGIGSSSMLAEKLEKAAKELGIEVkVEAQGLSEVIDLADADLIISTVPLAARFL----GKPVIVVSPLLNEKD 76
|
....
gi 1252954522 460 YNDL 463
Cdd:cd00133 77 GEKI 80
|
|
| FrwC |
COG1299 |
Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and ... |
48-347 |
6.00e-05 |
|
Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism];
Pssm-ID: 440910 [Multi-domain] Cd Length: 469 Bit Score: 46.03 E-value: 6.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 48 TLAQLVGPMITYLLPLLIGYT----GGR--LVGGERGGIVGAITTMGvivgadmpmFMGAMIAGPLGGYAIKrfdlWIEG 121
Cdd:COG1299 178 ALFQIGGAAFGLMVPVLAGYIaysiADRpgLAPGFIGGLLANNIGAG---------FLGGIIAGFLAGYVVL----WLKK 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 122 KVK-----TGFE--MLVNNFSSGIIGMLLailaYLAIGPLVAGLSKILAAGVNVMVENNLLPLTSIF-----------VE 183
Cdd:COG1299 245 KIKlpkslEGLKpiLIIPLLGTLITGLLM----IYVIGPPIAALNTALTNWLNSMSGSNAVLLGAILgammafdmggpVN 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 184 PAKILFLNNAINHGIFSPLGIQQAtetgasifflieANPGPGLGVLLAYMFFGKG--NAKQSAPGAAIIHFFGGIHEIYF 261
Cdd:COG1299 321 KAAYAFGTGLLASGIYAPMAAVMA------------AGMVPPLGLALATLLFKKKftEEEREAGKAAFILGLSFITEGAI 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 262 PYVLMNP-RLILAVILGGM-TGVFVMnLFHAGLvsPASPGSIFAVLLMTPkssLVGVILSVTSATLVSFIVsAILLKKTR 339
Cdd:COG1299 389 PFAAADPlRVIPSNMIGSAvAGALSM-LFGVTL--PAPHGGIFVLPLVSN---PLLYLLAIAIGTVVTALL-LGLLKKPV 461
|
....*...
gi 1252954522 340 IGDDDELE 347
Cdd:COG1299 462 EKKEEAAE 469
|
|
| SgaB |
COG3414 |
Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and ... |
381-456 |
1.98e-04 |
|
Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and metabolism];
Pssm-ID: 442640 Cd Length: 94 Bit Score: 40.54 E-value: 1.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 381 NIIVACDAGMGSSAMgagvLAKKVRDAgL--LGI--SVSNMAINDLP---DNVDIVITHKDLTQRAKTFAPNAmhISLTN 453
Cdd:COG3414 3 KILVVCGSGLGTSTM----LKMKIEKV-LkeLGIdaEVEHCDVSSAKskaDDADLIVTTTDLAEELGIPVINV--IPLLN 75
|
...
gi 1252954522 454 FLD 456
Cdd:COG3414 76 GID 78
|
|
| PRK10896 |
PRK10896 |
PTS IIA-like nitrogen regulatory protein PtsN; |
543-644 |
2.65e-04 |
|
PTS IIA-like nitrogen regulatory protein PtsN;
Pssm-ID: 182818 [Multi-domain] Cd Length: 154 Bit Score: 41.66 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252954522 543 EAMLAREKLTSTYLGESIAVPHGTIEaKDRVLKTGIVIcQYPEGVQFGEEPDEIARLVIGI---AAQNNEHIEVITRITS 619
Cdd:PRK10896 51 EAILTREKMGSTGIGNGIAIPHGKLE-EDTLRAVGVFV-QLEQPIAFDAIDNQPVDLLFALlvpADQCKTHLHTLSLVAK 128
|
90 100
....*....|....*....|....*
gi 1252954522 620 ALDEDGVIERLCETQDVQEVLEILA 644
Cdd:PRK10896 129 RLADKTICRRLRAAQSDEELYQIIT 153
|
|
| |
