|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-786 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1644.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 1 MVEYVVSLDKLGAHDVEHVGGKNASLGEMISNLAGAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 81 KTGAQIRQWIMEAEFPEKLNAEIRTAFAALSQGNPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECFA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 161 SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK 240
Cdd:PRK06464 163 SLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVHK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 241 QTLEAGRPAILRRNLGSKAIKMIYGDEAKAGksVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDG 320
Cdd:PRK06464 243 PTLKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 321 DDGKLYIVQARPETVKSRSAGNVMERYLLKETGTVLAEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:PRK06464 321 DDGKLYIVQARPETVKSRKEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVSCAEGDTGFIFEGELGFDIKKNSVDAMPDLP 480
Cdd:PRK06464 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETP 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYDGLPQEIKDSVDKRIAGYNDPVGFYVEKLVEGI 560
Cdd:PRK06464 481 TKIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 561 STLAAAFAPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVRNEMGFTNVEI 640
Cdd:PRK06464 561 ATVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEV 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 641 MVPFVRTLGEASQVIDLLAENGLKRGENGLRVIMMCELPSNAILAEEFLEFFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:PRK06464 641 MIPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLF 720
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236846438 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLALWLMEQGIESVSLNPDTVLETWFFLAE 786
Cdd:PRK06464 721 DERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAE 786
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-786 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1269.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 4 YVVSLDKLGAHDVEHVGGKNASLGEMISNLAGAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALAKTG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 84 AQIRQWIMEAEFPEKLNAEIRTAFAALSQ--GNPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFAS 161
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLSEdyGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 162 LFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKQ 241
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 242 TLEAGRPAILRRNLGSKAIKMIYgDEAKAGKSVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGD 321
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVY-DPDGGGVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 322 DGKLYIVQARPETVKSR-SAGNVMERYLLKETGTVLAEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:TIGR01418 320 DGEIFIVQARPETVQSRkKKENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVSCAEGDTGFIFEGELGFDIKKNSVDAMPDLP 480
Cdd:TIGR01418 400 AMKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYDGLPQEIKDSVDKRIAGynDPVGFYVEKLVEGI 560
Cdd:TIGR01418 480 TKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 561 STLAAAFAPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVRNEMGFTNVEI 640
Cdd:TIGR01418 558 AKVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 641 MVPFVRTLGEASQVIDLLAENGLKRGENGLRVIMMCELPSNAILAEEFLEFFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:TIGR01418 638 MIPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLF 717
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236846438 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLALWLMEQGIESVSLNPDTVLETWFFLAE 786
Cdd:TIGR01418 718 DERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-459 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 673.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 1 MVEYVVSLDKLGAHDVEHVGGKNASLGEMISnlagAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 81 KTGAQIRQWIMEAEFPEKLNAEIRTAFAALSQG-NPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVF 159
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKfGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 160 ASLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVH 239
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 240 KqtleagrPAILRRNLGSKAIKMIYGDeakagkSVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKd 319
Cdd:COG0574 237 K-------PTILERTLGSKAIKMVYDG------GTVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAI- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 320 gDDGKLYIVQARPETVKSRSAGN--------VMERYLL--------KETGTVLAEGRAIGQRIGAGKVRIIKDVSEMDKV 383
Cdd:COG0574 303 -DDGKLYILQTRPITVLEGLITKeallrvdpAQLDQLLhprfdpkaKEEGEVLAKGLPASPGAASGKVVFIADEAELARF 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236846438 384 QPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVscaEGDTGFI 459
Cdd:COG0574 382 QEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
16-351 |
1.17e-162 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 474.00 E-value: 1.17e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 16 VEHVGGKNASLGEMisnLAGAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALAKTGAQIRQWIMEAEF 95
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 96 PEKLNAEIRTAFAALSQ--GNPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFASLFNDRAISYRVH 173
Cdd:pfam01326 78 PEELEEAIREAYEELGKkfGDEPLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 174 QGFDHKLVALSAGVQRMVRSEtgTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKQTLEagrpaILRR 253
Cdd:pfam01326 158 KGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTLE-----ILRR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 254 NLGSKAIKMIYGDeakAGKSVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGDDGKLYIVQARPE 333
Cdd:pfam01326 231 TIGEKEIKMVYDE---GGEGTKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPE 307
|
330
....*....|....*....
gi 1236846438 334 TVKSR-SAGNVMERYLLKE 351
Cdd:pfam01326 308 TVWSEaMEKIAAEILEEGL 326
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-786 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1644.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 1 MVEYVVSLDKLGAHDVEHVGGKNASLGEMISNLAGAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 81 KTGAQIRQWIMEAEFPEKLNAEIRTAFAALSQGNPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECFA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 161 SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK 240
Cdd:PRK06464 163 SLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVHK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 241 QTLEAGRPAILRRNLGSKAIKMIYGDEAKAGksVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDG 320
Cdd:PRK06464 243 PTLKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 321 DDGKLYIVQARPETVKSRSAGNVMERYLLKETGTVLAEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:PRK06464 321 DDGKLYIVQARPETVKSRKEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVSCAEGDTGFIFEGELGFDIKKNSVDAMPDLP 480
Cdd:PRK06464 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETP 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYDGLPQEIKDSVDKRIAGYNDPVGFYVEKLVEGI 560
Cdd:PRK06464 481 TKIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 561 STLAAAFAPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVRNEMGFTNVEI 640
Cdd:PRK06464 561 ATVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEV 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 641 MVPFVRTLGEASQVIDLLAENGLKRGENGLRVIMMCELPSNAILAEEFLEFFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:PRK06464 641 MIPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLF 720
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236846438 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLALWLMEQGIESVSLNPDTVLETWFFLAE 786
Cdd:PRK06464 721 DERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAE 786
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-786 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1269.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 4 YVVSLDKLGAHDVEHVGGKNASLGEMISNLAGAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALAKTG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 84 AQIRQWIMEAEFPEKLNAEIRTAFAALSQ--GNPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFAS 161
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLSEdyGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 162 LFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKQ 241
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 242 TLEAGRPAILRRNLGSKAIKMIYgDEAKAGKSVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGD 321
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVY-DPDGGGVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 322 DGKLYIVQARPETVKSR-SAGNVMERYLLKETGTVLAEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:TIGR01418 320 DGEIFIVQARPETVQSRkKKENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVSCAEGDTGFIFEGELGFDIKKNSVDAMPDLP 480
Cdd:TIGR01418 400 AMKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYDGLPQEIKDSVDKRIAGynDPVGFYVEKLVEGI 560
Cdd:TIGR01418 480 TKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 561 STLAAAFAPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVRNEMGFTNVEI 640
Cdd:TIGR01418 558 AKVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 641 MVPFVRTLGEASQVIDLLAENGLKRGENGLRVIMMCELPSNAILAEEFLEFFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:TIGR01418 638 MIPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLF 717
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236846438 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLALWLMEQGIESVSLNPDTVLETWFFLAE 786
Cdd:TIGR01418 718 DERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-459 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 673.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 1 MVEYVVSLDKLGAHDVEHVGGKNASLGEMISnlagAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 81 KTGAQIRQWIMEAEFPEKLNAEIRTAFAALSQG-NPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVF 159
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKfGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 160 ASLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVH 239
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 240 KqtleagrPAILRRNLGSKAIKMIYGDeakagkSVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKd 319
Cdd:COG0574 237 K-------PTILERTLGSKAIKMVYDG------GTVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAI- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 320 gDDGKLYIVQARPETVKSRSAGN--------VMERYLL--------KETGTVLAEGRAIGQRIGAGKVRIIKDVSEMDKV 383
Cdd:COG0574 303 -DDGKLYILQTRPITVLEGLITKeallrvdpAQLDQLLhprfdpkaKEEGEVLAKGLPASPGAASGKVVFIADEAELARF 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236846438 384 QPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVscaEGDTGFI 459
Cdd:COG0574 382 QEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
16-351 |
1.17e-162 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 474.00 E-value: 1.17e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 16 VEHVGGKNASLGEMisnLAGAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALAKTGAQIRQWIMEAEF 95
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 96 PEKLNAEIRTAFAALSQ--GNPDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFASLFNDRAISYRVH 173
Cdd:pfam01326 78 PEELEEAIREAYEELGKkfGDEPLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 174 QGFDHKLVALSAGVQRMVRSEtgTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKQTLEagrpaILRR 253
Cdd:pfam01326 158 KGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTLE-----ILRR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 254 NLGSKAIKMIYGDeakAGKSVKVIDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGDDGKLYIVQARPE 333
Cdd:pfam01326 231 TIGEKEIKMVYDE---GGEGTKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPE 307
|
330
....*....|....*....
gi 1236846438 334 TVKSR-SAGNVMERYLLKE 351
Cdd:pfam01326 308 TVWSEaMEKIAAEILEEGL 326
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
1-334 |
1.89e-97 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 322.22 E-value: 1.89e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 1 MVEYVVSLDKLGAHDVEHVGGKNASLGEMiSNlagAGVSVPGGFATTSQAYRDFLELSGLNDQIHAALDALDVDDVNALA 80
Cdd:PRK06241 1 MSSYVLDFQEIDKTQLPLVGGKGANLGEL-SR---AGIPVPEGFCVTTEAYKKFLEQNEEFDALLDQLSALKLEDREQIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 81 KTGAQIRQWIMEAEFPEKLNAEIRTAFAALSQgnpDMAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA 160
Cdd:PRK06241 77 EISAKIREVIEAIEIPEDIVEAIAAALSKFGE---DHAYAVRSSATAEDLPTASFAGQQDTYLNVIGKDAILQHIRKCWA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 161 SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSEtgTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK 240
Cdd:PRK06241 154 SLFTERAVIYRIQNGFDHRKVYMSVVVQKMVFPE--ASGIMFTADPVTGNRKVLSIDASFGLGEALVSGLVSADTYKVRE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 241 qtleagrPAILRRNLGSKAIkMIYGdeAKAGKSVKViDVEKADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKdg 320
Cdd:PRK06241 232 -------GKIIDKTIATKKL-AIYA--LKEGGTETK-EIEPEQQKSQTLTDEQILELARLGRKIEAHFGCPQDIEWCL-- 298
|
330
....*....|....
gi 1236846438 321 DDGKLYIVQARPET 334
Cdd:PRK06241 299 ADGTFYILQSRPIT 312
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
481-778 |
1.05e-64 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 217.56 E-value: 1.05e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIInrmigvhpkalLNYDGLPqeikdsvdkriagyndpvgfYVEKLVEGI 560
Cdd:pfam02896 20 IKVAANIGTPDDAEAALANGAEGIGLYRTEFLF-----------MDRDELP--------------------TEDEQFEAY 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 561 STLAAAFAPKKVIVRLSDFKSNEYanLIGGklYEPEEENPMLGFRGASRYISEnfRDCFELECRALKRVRnemGFTNVEI 640
Cdd:pfam02896 69 KGVLEAMNGRPVTVRTLDIGGDKE--LPYL--EEPEEMNPFLGWRGIRIGLDR--PELFRTQLRAILRAS---AFGNLRI 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 641 MVPFVRTLGEASQVIDLLAENGLKRGEN-----GLRVIMMCELPSNAILAEEFLEFFDGFSIGSNDLTQLTLGLDRDSGV 715
Cdd:pfam02896 140 MFPMVASVEELREAKAIIEEVKEELDAEvgfdkDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNER 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1236846438 716 IAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDhPDLALWLMEQGIESVSLNPDTVL 778
Cdd:pfam02896 220 VAYLYDPLHPAVLRLIKEVIRAAHRHGKWVGICGEMAGD-PSAVPLLVGLGLDEFSMSPDSVP 281
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
360-780 |
4.94e-52 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 190.67 E-value: 4.94e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 360 RAIGQRIgagkVRIIKDVSEMD--KVQPGDVLV------SDMT--DPdwepvmKRASAIVTNRGGRTCHAAIIARELGIP 429
Cdd:COG1080 130 RDVGRRV----LRNLLGVEAPDlsDLPEPVILVahdltpSDTAqlDP------SRVAGFVTDLGGRTSHTAILARSLGIP 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 430 AVVGCGNATQLLKDGQGVTVscaEGDTGFIF----EGEL--------GFDIKKNSVDAMPDLP--------FKIMMNVGN 489
Cdd:COG1080 200 AVVGLGDALLLVKDGDLVIV---DGDAGVVIvnpdEETLaeyrerqaEYAAERAELARLRDLPavtldgvrVELAANIGL 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 490 PDrafDFAQLPNA---GVGLARLEFIinrmigvhpkaLLNYDGLPQEikdsvdkriagyndpvgfyvEKLVEGISTLAAA 566
Cdd:COG1080 277 PE---DAAAALENgaeGVGLFRTEFL-----------FMDRDDLPTE--------------------EEQFEAYRAVAEA 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 567 FAPKKVIVRLSDfksneyanlIGG-K----LYEPEEENPMLGFRGAsRYiSENFRDCFELECRALKRVRNemgFTNVEIM 641
Cdd:COG1080 323 MGGRPVTIRTLD---------IGGdKplpyLPLPKEENPFLGLRAI-RL-CLDRPELFRTQLRAILRASA---HGNLRIM 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 642 VPFVRTLGEASQVIDLLAE-------NGLKRGENgLRVIMMCELPSNAILAEEFLEFFDGFSIGSNDLTQLTLGLDRDSG 714
Cdd:COG1080 389 FPMISSVEELRQAKALLEEakaelraEGIPFDED-IPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNE 467
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236846438 715 VIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDhPDLALWLMEQGIESVSLNPDTVLET 780
Cdd:COG1080 468 KVAYLYDPLHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGD-PLATPLLLGLGLDELSMSPSSIPAV 532
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
409-778 |
1.26e-38 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 151.87 E-value: 1.26e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 409 VTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVSCAEGDTGFIFEGElgfDIK------------KNSVDAM 476
Cdd:TIGR01417 179 LTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKGIVIFNPSSE---TIDkyeakqeavsseKAELAKL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 477 PDLPFK--------IMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMigvhpkallnyDGLPQEikdsvDKRIAGYndp 548
Cdd:TIGR01417 256 KDKPAItldghqveLAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSR-----------DQLPTE-----EEQFAAY--- 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 549 vgfyveklvegiSTLAAAFAPKKVIVRLSDF---KSNEYANLiggklyePEEENPMLGFRgASRYISENfRDCFELECRA 625
Cdd:TIGR01417 317 ------------KTVLEAMESDAVIVRTLDIggdKELPYLNF-------PKEENPFLGYR-AIRLALER-EEILRTQLRA 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 626 LKRVRNemgFTNVEIMVPFVRTLGEASQV-------IDLLAENGLKRGENgLRVIMMCELPSNAILAEEFLEFFDGFSIG 698
Cdd:TIGR01417 376 ILRASA---YGKLRIMFPMVATVEEIRAVkqeleeeKQELNDEGKAFDEN-IEVGVMIEIPSAALIADHLAKEVDFFSIG 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 699 SNDLTQLTLGLDRDSGVIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPdLALWLMEQGIESVSLNPDTVL 778
Cdd:TIGR01417 452 TNDLTQYTLAVDRGNDLISNLYQPYNPAVLRLIKLVIDAAKAEGIWVGMCGEMAGDER-AIPLLLGLGLRELSMSASSIL 530
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
353-463 |
2.66e-34 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 133.87 E-value: 2.66e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 353 GTVLAEGRAIGQRIGAGKVRIIKDVSE-MDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAV 431
Cdd:COG3848 209 GDVLAKGQGIGRGSVTGKAVVARSAEEaLEKFEEGDILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPVI 288
|
90 100 110
....*....|....*....|....*....|..
gi 1236846438 432 VGCGNATQLLKDGQGVTVscaEGDTGFIFEGE 463
Cdd:COG3848 289 VGAEGATEILKDGQVVTV---DAERGVVYRGA 317
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
409-750 |
8.44e-34 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 137.45 E-value: 8.44e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 409 VTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDG---------QGVTVSCAEGDTGFIFEGELGFDIKKNSVDAMPDL 479
Cdd:PRK11177 180 ITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGdylildavnNQIYVNPTNEVIEELKAVQEQYASEKAELAKLKDL 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 480 P--------FKIMMNVGNPdRAFDFAQLPNA-GVGLARLEFIinrmigvhpkaLLNYDGLPQEikdsvdkriagyndpvg 550
Cdd:PRK11177 260 PaitldghqVEVCANIGTV-RDVEGAERNGAeGVGLYRTEFL-----------FMDRDALPTE----------------- 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 551 fyvEKLVEGISTLAAAFAPKKVIVRLSDF---KSNEYANLiggklyePEEENPMLGFRgASRyISENFRDCFELECRALK 627
Cdd:PRK11177 311 ---EEQFQAYKAVAEAMGSQAVIVRTMDIggdKELPYMNL-------PKEENPFLGWR-AIR-IAMDRKEILHDQLRAIL 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 628 RVRnemGFTNVEIMVPF------VRTL-GEASQVIDLLAENGLKRGENgLRVIMMCELPSNAILAEEFLEFFDGFSIGSN 700
Cdd:PRK11177 379 RAS---AFGKLRIMFPMiisveeVRELkAEIEILKQELRDEGKAFDES-IEIGVMVETPAAAVIARHLAKEVDFFSIGTN 454
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1236846438 701 DLTQLTLGLDRDSGVIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQ 750
Cdd:PRK11177 455 DLTQYTLAVDRGNELISHLYNPMSPSVLNLIKQVIDASHAEGKWTGMCGE 504
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
382-454 |
6.94e-32 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 118.28 E-value: 6.94e-32
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1236846438 382 KVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTVSCAEG 454
Cdd:pfam00391 1 KLPEGVILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDGSTG 73
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
353-455 |
6.16e-26 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 113.48 E-value: 6.16e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 353 GTVLAEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVV 432
Cdd:PRK06354 479 GAVVAKGQGIGRKSVSGKARVAKTAAEVAKVNEGDILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLGIPVIV 558
|
90 100
....*....|....*....|...
gi 1236846438 433 GCGNATQLLKDGQGVTVSCAEGD 455
Cdd:PRK06354 559 GVKNATSLIKDGQIITVDAARGV 581
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
5-479 |
1.20e-25 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 111.76 E-value: 1.20e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 5 VVSLDKLGAHDVEHVGGKNASLGEMISNlagaGVSVPGGFATTSQAYRDFLE-----LSGLNDQIHAALDALDvddvnal 79
Cdd:PRK05878 9 VVLLDGGANQPRELLGGKGHGIDMMRRL----GLPVPPAFCITTEVCVRYLAdpgstIDAIWDDVLDRMRWLE------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 80 AKTGAQIRQWimeaefPEKLNAEIRTAfAALSQgnPDMAVAVRS--------SATAEDLPDASFAGQ-----QETFLNIR 146
Cdd:PRK05878 78 AETGRTFGRG------PRPLLVSVRSG-AAQSM--PGMMDTILNlgindaveQALAAEGGDPDFAADtrrrfTEMYRRIV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 147 GVENVI--------RAAKE-VFASLFNDRAISYRVHQGFDHKLvALSAGVQRMV---RSETGTAGVMFTLDTESGfRDVV 214
Cdd:PRK05878 149 GSGSPPpddpyeqlRAAIEaVFASWNSPRAVAYRRHHGLDDDG-GTAVVVQAMVfgnLDANSGTGVLFSRNPITG-ANEP 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 215 FitGAY---GLGETVVQGAVNPDefyvHKQTLEAGRPAILRrnlgskaikmiygdeakagksvkvidvekadrarfcltd 291
Cdd:PRK05878 227 F--GEWlpgGQGEDVVSGLVDVA----PITALRDEQPAVYD--------------------------------------- 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 292 aevsELAKQAMIIEKHYKCPMDIEWAKDgdDGKLYIVQARP------------------------ETVKSRSAGNVmeRY 347
Cdd:PRK05878 262 ----ELMAAARTLERLGRDVQDIEFTVE--SGKLWLLQTRSakrsaqaavrlalqlhdegliddaEALRRVTPTHV--ET 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 348 LLKET--------GTVLAEGRAIGQRIGAGKVriIKDVSE-MDKVQPGD--VLVSDMTDPDWEPVMKRASAIVTNRGGRT 416
Cdd:PRK05878 334 LLRPSlqpearlaAPLLAKGLPACPGVVSGTA--YTDVDEaLDAADRGEpvILVRDHTRPDDVHGMLAAQGIVTEVGGAT 411
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1236846438 417 CHAAIIARELGIPAVVGCGNATQLLKDGQGVTVscaEGDTGFIFEGELGFDIKknSVDAMPDL 479
Cdd:PRK05878 412 SHAAVVSRELGRVAVVGCGAGVAAALAGKEITV---DGYEGEVRQGVLALSAW--SESDTPEL 469
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
369-459 |
1.53e-25 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 112.06 E-value: 1.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 369 GKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVT 448
Cdd:PRK08296 512 GPARVIRSADELSEVQEGEILVCPVTSPSWAPIFAKIKATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIKTGQRLR 591
|
90
....*....|.
gi 1236846438 449 VscaEGDTGFI 459
Cdd:PRK08296 592 V---DGTKGVV 599
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
369-459 |
9.13e-23 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 104.20 E-value: 9.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 369 GKVRIIKDVsEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVT 448
Cdd:PRK06241 780 GRARVILNP-EDADLEKGDILVTAFTDPGWTPLFVSIKGLVTEVGGLMTHGAVIAREYGIPAVVGVENATKLIKDGQRIR 858
|
90
....*....|.
gi 1236846438 449 VscaEGDTGFI 459
Cdd:PRK06241 859 V---DGTEGYV 866
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
403-777 |
1.50e-21 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 100.07 E-value: 1.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 403 KRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVTvscaEGDTGFIF-----------------EGELG 465
Cdd:PRK11061 341 DRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLLHQRLLIV----DGYRGELLvdpepvllqeyqrliseEIELS 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 466 FDIKKNSvdampDLP--------FKIMMNVGnpdRAFDFAQLPNA---GVGLARLE--FIINRmigvhpkallnydGLPQ 532
Cdd:PRK11061 417 RLAEDDV-----NLPaqlksgerIKVMLNAG---LSAEHEEKLGSrvdGVGLYRTEipFMLQS-------------GFPS 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 533 EikdsvDKRIAGYndpvgfyveklvEGISTLaaaFAPKKVIVRLSDfksneyanlIGG--KL-YEP-EEENPMLGFRGAS 608
Cdd:PRK11061 476 E-----EEQVAQY------------QGMLQM---FPDKPVTLRTLD---------IGAdkQLpYMPiSEENPCLGWRGIR 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 609 ryISENFRDCFELECRALKRVRNEMGftNVEIMVPFVRTLGEASQVIDLL------AENGLKRGENGLRVIMMCELPSNA 682
Cdd:PRK11061 527 --ITLDQPEIFLIQVRAMLRANAATG--NLSILLPMVTSIDEVDEARRLIdragreVEEMLGYEIPKPRIGIMIEVPSMV 602
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 683 ILAEEFLEFFDGFSIGSNDLTQLTLGLDRDSGVIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDhPDLALWL 762
Cdd:PRK11061 603 FMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGD-PMGALLL 681
|
410
....*....|....*
gi 1236846438 763 MEQGIESVSLNPDTV 777
Cdd:PRK11061 682 IGLGYRHLSMNGRSV 696
|
|
| PRK05865 |
PRK05865 |
sugar epimerase family protein; |
369-455 |
1.95e-12 |
|
sugar epimerase family protein;
Pssm-ID: 235630 [Multi-domain] Cd Length: 854 Bit Score: 70.84 E-value: 1.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 369 GKVRIIKDvSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQLLKDGQGVT 448
Cdd:PRK05865 748 GRVRIVRP-ETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVE 826
|
....*..
gi 1236846438 449 VSCAEGD 455
Cdd:PRK05865 827 VDGATGE 833
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
86-340 |
8.64e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 46.13 E-value: 8.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 86 IRQWiMEAEfpEKLNAEIRTAFAAlsqgnpDMaVAVRSSATAEDLPDASFAGQQETFLNIRG--VENVIRAAKEVFASLf 163
Cdd:PRK05849 35 VREW-LSNK--DKVLEEIQNSFPA------DK-LIVRSSSRSEDSSSSSNAGAFLSILNVNAdsKDQLLKAIEKVIASY- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 164 ndraisyrvHQGFDHKLValsagVQRMVRsETGTAGVMFTLDTESGFRDVVfitgayglgetvvqgaVNPDefyvhkqtl 243
Cdd:PRK05849 104 ---------GTSKDDEIL-----VQPMLE-DIVLSGVAMSRDPESGAPYYV----------------INYD--------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236846438 244 EAGRPAILRRNLGSKAIKMIYGDEAKAGKSVKVidvekadrarfcltdAEVSELAKQamiIEKHYKC-PMDIEWAKDgDD 322
Cdd:PRK05849 144 ESGSTDSVTSGSGGSATTVYHYRDALVFKPPRL---------------KKLIELIRE---LEALFGCdFLDIEFAID-EK 204
|
250
....*....|....*...
gi 1236846438 323 GKLYIVQARPETVKSRSA 340
Cdd:PRK05849 205 EELYILQVRPITVPEKWN 222
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
395-435 |
1.04e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 42.66 E-value: 1.04e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1236846438 395 DP--DWePVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCG 435
Cdd:PRK05849 717 DPgyDW-LFTKGIAGLITCYGGANSHMAIRAAELGLPAVIGVG 758
|
|
| PRK11377 |
PRK11377 |
dihydroxyacetone kinase subunit M; Provisional |
412-454 |
3.24e-03 |
|
dihydroxyacetone kinase subunit M; Provisional
Pssm-ID: 183108 [Multi-domain] Cd Length: 473 Bit Score: 40.89 E-value: 3.24e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1236846438 412 RGGRTC-HAAIIARELGIPAVVGCGNATQLLKDGQGVTVSCAEG 454
Cdd:PRK11377 424 SAGSPLsHSAIIARELGIGWICQQGEKLYAIQPEETLTLDVKTQ 467
|
|
| |
