|
Name |
Accession |
Description |
Interval |
E-value |
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
37-773 |
0e+00 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 680.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 37 ARLNSSVLAMLPKQTLGAIPPALNDGFMQRLDRQLVWLVSPGKEPD-PRVAQQWLALLQSSDSLSEVKGPMDAaGQKAWG 115
Cdd:COG4258 30 LRFDTDILALLPADETDEQALLADQLREGPLSRQILVLISGGDPAQlAAAARALAAALRASGLFASVQNGIPA-DLEALR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 116 EFFWQHRNGLIDPATRARLQNGG-EAQAQWILSQLYSAFSGVSGKELQNDPLMLMRGSQLALAQNGQKLRLMDGWLVTQD 194
Cdd:COG4258 109 DFLFPHRYLLLPAADRERLTADGlRAALQDRLDQLYSPAGGVSKQLLLRDPLGLSRRLLEKLQPLGSRPRLRDGVLVSRD 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 195 EagnYWYLLHGELAGSSFDMQQTHRLVTTLNALQETLKARFPQAQLLSRGTVFYSDYASQQAKRDVSTLGIATLLGVFLL 274
Cdd:COG4258 189 G---TWALLLAETRASGFDTDAQQQLVAALRAAFAALNAAFPGAQLLLTGAGLFAVAAAQQIKHDISTIGLISLLGILLL 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 275 IVAVFRSLRPLLLSVLSIAIGALAGTVVTLLLFGELHLMTLVMSMSIIGISADYTLYYLTERMVHGaEHSPWQSLAKVRN 354
Cdd:COG4258 266 LLLVFRSLRPLLLGLLPVAVGALAGLAAVSLVFGSVHGITLGFGSSLIGVAVDYSLHYLTHRRAAG-EWDPRAALRRIWP 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 355 ALLLALLTTVAAYLIMMLAPFPGIRQMAVFAAVGLSASCLTVIFWHPWLCRGLPVRP-VPLMVIMLRWLAAWRRNKKLSV 433
Cdd:COG4258 345 TLLLGLLTTVLGYLALLFSPFPGLRQLGVFAAAGLLAAALTTLLWLPLLLPRAAPRPpAPALALLARLLARWPRRLRWLL 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 434 GLPVALALLSAVGMSTLRVDDDIAQLQALPKNILAQEKAITALTGQSVDQKWFVVHGASPQQTLERLEAFTPALAQAQKA 513
Cdd:COG4258 425 ALLAVLALASLLGLNRLKWNDDLRALNPVPAALLAQEARLRALLGAPDVSQYLVVYGPDAEQALQRNEALLPRLDALVAQ 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 514 GEIARWRTLP--LNSLARQKSDLTLLREAA---PAVTNVLKSAGLNA---------VSPNLDAMPVSVDAWLKSPASEGW 579
Cdd:COG4258 505 GAIAGYQSLSrlLPSAATQQARQALLPDLAalrPRLAEALAGLGFRPdafapfladLEAARAAPPLTPEDLLASPLAAAL 584
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 580 RLLWLTLPNGESGVLVPVDGAKNSAYLGELAARHDGVVWVDRKASFDSLFALYRTLLTGLLFAALAVIACGAMLRL-GWR 658
Cdd:COG4258 585 RLLLLGRKDGQWAALVPLRGVDDAAALRAAAAGLPGVRLVDRKAESSSLFGRYRNDALWLLLLALLLILLLLLLRLrSLR 664
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 659 KGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGIGINYTLFFSNP---RGTPLTSMLAITLAMMTTLLTLGML 735
Cdd:COG4258 665 RALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTEGlldKGELARTLLSILLAALTTLLGFGLL 744
|
730 740 750
....*....|....*....|....*....|....*...
gi 1236136426 736 VFSATQAISSFGIVLVSGIFTAFLLAPLAMPDKKERKR 773
Cdd:COG4258 745 AFSSTPALRSFGLTVLLGILLALLLAPLLAPRRRPRRA 782
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
643-766 |
3.10e-09 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 60.62 E-value: 3.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 643 ALAVIACGAMLRL---GWRKGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGIGINYTLFFSN----PRGTPL 715
Cdd:TIGR00921 200 AISGILVVLVLLLdfkRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNryeeERDIGR 279
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236136426 716 TS-----------MLAITLAMMTTLLTLGMLVFSATQAISSFGIVLVSGIFTAFLLAPLAMP 766
Cdd:TIGR00921 280 AKgeaivtavrrtGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLP 341
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
258-330 |
1.46e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 41.51 E-value: 1.46e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1236136426 258 RDVSTLGIATLLGVFLLIVAVFRSLRPLLLSVLSIAIG---ALAGTVVTLLLFG-ELHLMTLVMSMSI-IGISADYTL 330
Cdd:pfam03176 142 RDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSlgaAQGLVAILAHILGiGLSTFALNLLVVLlIAVGTDYAL 219
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
640-773 |
1.49e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 42.15 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 640 LFAALAVIACGAMLRLGWRKGLISLVPSVLSLSCGLAVLAATgH------PVNLFSLLALVLVLGIGINYTL-FFSNPRG 712
Cdd:PRK12911 1240 LFGALGIILLYVSLRFEWRYAFSAICALIHDLLATCAVLVAL-HfflqkiQIDLQAIGALMTVLGYSLNNTLiIFDRIRE 1318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 713 -------TPL----TSMLAITLA--MMTTLLTLG---MLVFSATQAISSFGIVLVSGIFTAFL----LAP---LAMPDKK 769
Cdd:PRK12911 1319 drqeklfTPMpiliNDALQKTLGrtVMTTATTLSvllILLFVGGGSIFNFAFIMTIGILLGTLsslyIAPpllLFMVRKE 1398
|
....
gi 1236136426 770 ERKR 773
Cdd:PRK12911 1399 ERNS 1402
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
37-773 |
0e+00 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 680.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 37 ARLNSSVLAMLPKQTLGAIPPALNDGFMQRLDRQLVWLVSPGKEPD-PRVAQQWLALLQSSDSLSEVKGPMDAaGQKAWG 115
Cdd:COG4258 30 LRFDTDILALLPADETDEQALLADQLREGPLSRQILVLISGGDPAQlAAAARALAAALRASGLFASVQNGIPA-DLEALR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 116 EFFWQHRNGLIDPATRARLQNGG-EAQAQWILSQLYSAFSGVSGKELQNDPLMLMRGSQLALAQNGQKLRLMDGWLVTQD 194
Cdd:COG4258 109 DFLFPHRYLLLPAADRERLTADGlRAALQDRLDQLYSPAGGVSKQLLLRDPLGLSRRLLEKLQPLGSRPRLRDGVLVSRD 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 195 EagnYWYLLHGELAGSSFDMQQTHRLVTTLNALQETLKARFPQAQLLSRGTVFYSDYASQQAKRDVSTLGIATLLGVFLL 274
Cdd:COG4258 189 G---TWALLLAETRASGFDTDAQQQLVAALRAAFAALNAAFPGAQLLLTGAGLFAVAAAQQIKHDISTIGLISLLGILLL 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 275 IVAVFRSLRPLLLSVLSIAIGALAGTVVTLLLFGELHLMTLVMSMSIIGISADYTLYYLTERMVHGaEHSPWQSLAKVRN 354
Cdd:COG4258 266 LLLVFRSLRPLLLGLLPVAVGALAGLAAVSLVFGSVHGITLGFGSSLIGVAVDYSLHYLTHRRAAG-EWDPRAALRRIWP 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 355 ALLLALLTTVAAYLIMMLAPFPGIRQMAVFAAVGLSASCLTVIFWHPWLCRGLPVRP-VPLMVIMLRWLAAWRRNKKLSV 433
Cdd:COG4258 345 TLLLGLLTTVLGYLALLFSPFPGLRQLGVFAAAGLLAAALTTLLWLPLLLPRAAPRPpAPALALLARLLARWPRRLRWLL 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 434 GLPVALALLSAVGMSTLRVDDDIAQLQALPKNILAQEKAITALTGQSVDQKWFVVHGASPQQTLERLEAFTPALAQAQKA 513
Cdd:COG4258 425 ALLAVLALASLLGLNRLKWNDDLRALNPVPAALLAQEARLRALLGAPDVSQYLVVYGPDAEQALQRNEALLPRLDALVAQ 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 514 GEIARWRTLP--LNSLARQKSDLTLLREAA---PAVTNVLKSAGLNA---------VSPNLDAMPVSVDAWLKSPASEGW 579
Cdd:COG4258 505 GAIAGYQSLSrlLPSAATQQARQALLPDLAalrPRLAEALAGLGFRPdafapfladLEAARAAPPLTPEDLLASPLAAAL 584
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 580 RLLWLTLPNGESGVLVPVDGAKNSAYLGELAARHDGVVWVDRKASFDSLFALYRTLLTGLLFAALAVIACGAMLRL-GWR 658
Cdd:COG4258 585 RLLLLGRKDGQWAALVPLRGVDDAAALRAAAAGLPGVRLVDRKAESSSLFGRYRNDALWLLLLALLLILLLLLLRLrSLR 664
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 659 KGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGIGINYTLFFSNP---RGTPLTSMLAITLAMMTTLLTLGML 735
Cdd:COG4258 665 RALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTEGlldKGELARTLLSILLAALTTLLGFGLL 744
|
730 740 750
....*....|....*....|....*....|....*...
gi 1236136426 736 VFSATQAISSFGIVLVSGIFTAFLLAPLAMPDKKERKR 773
Cdd:COG4258 745 AFSSTPALRSFGLTVLLGILLALLLAPLLAPRRRPRRA 782
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
244-774 |
7.96e-31 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 129.59 E-value: 7.96e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 244 GTVFYSDYASQQAKRDVSTLGIATLLGVFLLIVAVFRSLRPLLLSVLSIAIGALAGTVVTLLLFGELHLMTLVMSMSIIG 323
Cdd:COG1033 204 GFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 324 ISADYTLYYLT---ERMVHGA--EHSPWQSLAKVRNALLLALLTTVAAYLIMMLAPFPGIRQMAVFAAVGLSASCLTVIF 398
Cdd:COG1033 284 IGIDYGIHLLNryrEERRKGLdkREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLT 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 399 WHPWLCRGLPVRP--------VPLMVIMLRWLAAW-RRNKKLSVGLPVALALLSAVGMSTLRVDDDIAQLqaLPKN---I 466
Cdd:COG1033 364 LLPALLSLLPRPKpktrrlkkPPELGRLLAKLARFvLRRPKVILVVALVLAVVSLYGISRLKVEYDFEDY--LPEDspiR 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 467 LAQEKAITALTGQSVdqkWFVV------HGASPQQTLERLEAFTpalAQAQKAGEIArwRTLPLNSLARQKSDltLLREA 540
Cdd:COG1033 442 QDLDFIEENFGGSDP---LEVVvdtgepDGLKDPEVLKEIDRLQ---DYLESLPEVG--KVLSLADLVKELNQ--ALNEG 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 541 APAVTNVLKSAGLNAVSPNLDAMPVSVDawLKSPASEGWRL--LWLTLPNGESGVLVP-VDGAKnsAYLGELAARHDGVV 617
Cdd:COG1033 512 DPKYYALPESRELLAQLLLLLSSPPGDD--LSRFVDEDYSAarVTVRLKDLDSEEIKAlVEEVR--AFLAENFPPDGVEV 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 618 WVdrkASFDSLFA-----LYRTLLTGLLFAALAV-IACGAMLRlGWRKGLISLVPSVLSLSCGLAVLAATGHPVNLFSLL 691
Cdd:COG1033 588 TL---TGSAVLFAainesVIESQIRSLLLALLLIfLLLLLAFR-SLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAV 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 692 ALVLVLGIGINYTLFFSN-------PRGTPLTSML--------AITLAMMTTLLTLGMLVFSATQAISSFGIVLVSGIFT 756
Cdd:COG1033 664 VASIALGIGVDYTIHFLSryreerrKGGDLEEAIRralrttgkAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGLLV 743
|
570 580
....*....|....*....|....
gi 1236136426 757 AFLLAPLAMP------DKKERKRK 774
Cdd:COG1033 744 ALLAALLLLPalllllDPRIAKKR 767
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
643-766 |
3.10e-09 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 60.62 E-value: 3.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 643 ALAVIACGAMLRL---GWRKGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGIGINYTLFFSN----PRGTPL 715
Cdd:TIGR00921 200 AISGILVVLVLLLdfkRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNryeeERDIGR 279
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236136426 716 TS-----------MLAITLAMMTTLLTLGMLVFSATQAISSFGIVLVSGIFTAFLLAPLAMP 766
Cdd:TIGR00921 280 AKgeaivtavrrtGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLP 341
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
217-403 |
1.39e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 58.33 E-value: 1.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 217 THRLVTTLNALQETLKARFP----QAQLLSRGTVFYsdYASQQAKRDVSTLGIATLLGVFLLIVAVFRSLRPLLLSVLSI 292
Cdd:COG1033 562 SEEIKALVEEVRAFLAENFPpdgvEVTLTGSAVLFA--AINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPN 639
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 293 AIGALAGTVVTLLLFGELHLMTLVMSMSIIGISADYTLYYLT----ERMVHG-AEHSPWQSLAKVRNALLLALLTTVAAY 367
Cdd:COG1033 640 LLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSryreERRKGGdLEEAIRRALRTTGKAILFTSLTLAAGF 719
|
170 180 190
....*....|....*....|....*....|....*.
gi 1236136426 368 LIMMLAPFPGIRQMAVFAAVGLSASCLTVIFWHPWL 403
Cdd:COG1033 720 GVLLFSSFPPLADFGLLLALGLLVALLAALLLLPAL 755
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
259-401 |
2.43e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.46 E-value: 2.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 259 DVSTLGIATLLGVFLLIVAVFRSLRPLLLSVLSIAIGALAGTVVTLLLFGELHLMTLVMSMSIIGISADYTLY----YLT 334
Cdd:TIGR00921 568 GMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHlaerYFE 647
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236136426 335 ERMVHGAEHSPWQSLAKVRNALLLALLTTVAAYLIMMLAPFPGIRQMAVFAAVGLSASCLTVIFWHP 401
Cdd:TIGR00921 648 ERKEHGPKEAITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFP 714
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
588-699 |
2.32e-05 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 48.18 E-value: 2.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 588 NGESGVLVPVDGAKNS----------AYLGELAARH-DGV---VWVDRkASF--DSLFALYRTLLTGLLFAALAVIAcga 651
Cdd:COG0841 275 NGKPAVGLAIQKQPGAnalevadavrAKLEELQASLpEGVeltIVYDQ-SEFirASIEEVVKTLLEAILLVVLVVFL--- 350
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1236136426 652 MLRlGWRkglISLVPSV---LSLSCGLAVLAATGHPVNLFSLLALVLVLGI 699
Cdd:COG0841 351 FLR-SWR---ATLIPAVaipVSLIGTFAVMYLLGFSLNILTLFALVLAIGI 397
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
211-350 |
6.81e-05 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 46.30 E-value: 6.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 211 SFDMQQTHRLVTTLNALQETLK-ARFPQAQLLSRGTVFYSDYASQQAKRDVSTLGIATLLGVFLLIVAVFRSLR----PL 285
Cdd:COG2409 121 TLDGDAGDEAAEAVDALRDAVAaAPAPGLTVYVTGPAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVaallPL 200
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1236136426 286 LLSVLSIAIGALAGTVVTLLLfgELHLMTL-VMSMSIIGISADYTLYYLT---ERMVHGaeHSPWQSLA 350
Cdd:COG2409 201 LTAGLAVGVALGLLALLAAFT--DVSSFAPnLLTMLGLGVGIDYALFLVSryrEELRAG--EDREEAVA 265
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
248-769 |
8.61e-05 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 46.14 E-value: 8.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 248 YSDYASQQAKRDVStlGIATLLGVFLLIVAVFRSLRPLLLSVLSIAIGALAGTVVTLLLFGELHLMTLVMSMSIIGISAD 327
Cdd:TIGR03480 261 DEELATVSEGATVA--GLLSFVLVLVLLWLALRSPRLVFAVLVTLIVGLILTAAFATLAVGHLNLISVAFAVLFIGLGVD 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 328 YTLYYLTE-RMVHGAEHSPWQSLAKVRNALLLALLTTVAAYLIMMLAPFP----GIRQMAVFAAVGLSASCLTVIFWHPW 402
Cdd:TIGR03480 339 FAIQFSLRyREERFRGGNHREALSVAARRMGAALLLAALATAAGFFAFLPtdykGVSELGIIAGTGMFIALFVTLTVLPA 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 403 LCRGLPVR------PVPLMVIMLRWLaawRRNKKLSVGLPVALALLSAVGMSTLRVDDDIAQLQAlPKnilaqekaital 476
Cdd:TIGR03480 419 LLRLLRPPrrrkppGYATLAPLDAFL---RRHRRPVLGVTLILGIAALALLPQLRFDFNPLNLQD-PK------------ 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 477 tGQSVdqKWFVVHGASPQQTLERLEAFTPALAQAQ-------KAGEIARWRTLPLNSLARQKSDLTLLREAA------PA 543
Cdd:TIGR03480 483 -TESV--RTFLELLADPDTSPYSAEVLAPSAPEARalterleALPEVDQVVTLPDFVPDDQEAKLALIADLAlvlgptLN 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 544 VTNVLKSAGLNAVSPNLDAMPVSVDAWLKSP-----------ASEGWRLLWL------TLPNGESGVLVPVDGAKN---- 602
Cdd:TIGR03480 560 PGEADPAPSAEEVAAALRRLAARLRAAAAKSqdpdaaaagrlAASLDRLLAKapaqaaTLRALQGALLAGLPGELDrlrd 639
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 603 ---------------------------------SAYLGELAARH---DGVVWVDRKASFD--SLFALYRTLLTGLLFAA- 643
Cdd:TIGR03480 640 slqaepvtledlppdlrrrwvakdgrarlevfpKEDLNDNEALRrfvRAVRKVAPDATGApvSILESGDTVVGAFLQAFi 719
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 644 LAVIACGAMLRLGWRKG---LISLVPSVLS--LSCGLAVLAatGHPVNLFSLLALVLVLGIGINYTLFFSN------PRG 712
Cdd:TIGR03480 720 YALVAITVLLLLTLRRVrdvLLVLAPLLLAglLTVAAMVLL--GIPFNFANIIALPLLLGLGVDFGIYMVHrwrngvDSG 797
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1236136426 713 TPLTS--MLAITLAMMTTLLTLGMLVFSATQAISSFGIVLVSGI------FTAFLLAPLAMPDKK 769
Cdd:TIGR03480 798 NLLQSstARAVFFSALTTATAFGSLAVSSHPGTASMGILLSLGLgltllcTLIFLPALLGKRRRG 862
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
658-766 |
9.68e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 45.98 E-value: 9.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 658 RKGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGIGINYTLFFS-------NPRG--TPLTSML-----AITL 723
Cdd:TIGR00921 592 IKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAeryfeerKEHGpkEAITHTMertgpGILF 671
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1236136426 724 AMMTTLLTLGMLVFSATQAISSFGIVLVSGIFTAFLLAPLAMP 766
Cdd:TIGR00921 672 SGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFP 714
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
184-422 |
2.01e-04 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 44.96 E-value: 2.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 184 RLMDGWLVTQDEAGNYWYLLHGELAGSSfDMQQTHRLVTTlnALQETLKARFP--QAQLLSRGTVFY--SDYASqqakRD 259
Cdd:TIGR00833 673 AVLDYFLSPDGHAARLLVYGDGSPAGDQ-GAQEFNAIRTV--AEEAIQRADLEpaKVELAGVSAVNRdlRDLVN----SD 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 260 VSTLGIATLLGVFLLIVAVFRSLRPLLLSVLSIAIGALA----GTVVTLLLFG-ELHLMTLVMSMS-IIGISADYTLYYL 333
Cdd:TIGR00833 746 LGLISIITLAIVFMILALLLRAPVAPIVLIGSVALSYLWalglSVLAFQHILGaELHWSVLAGVFVlLVALGVDYNMLLV 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 334 T---ERMVHGAEHSPWQSLAKVRNALLLALLTTVAAYLIMMLAPFPGIRQMAVFAAVGLSASCLTVifwhpwlcRGlpVR 410
Cdd:TIGR00833 826 SrikEESPAGNRTGIIRALGSTGGVITAAGLVFAGTMAALASAQLTAIAQFGFTVGVGILLDTFIV--------RS--VT 895
|
250
....*....|..
gi 1236136426 411 PVPLMVIMLRWL 422
Cdd:TIGR00833 896 VPALTLLLGRWI 907
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
639-756 |
5.92e-04 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 42.26 E-value: 5.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 639 LLFAALAVIACGAMLRLGWRKGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGIGINYTL---------FFSN 709
Cdd:TIGR00966 103 ALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTIIGYSINDTVvvfdrirenLRKY 182
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1236136426 710 PRGTPLTSM-LAIT-------LAMMTTLLTLGMLVFSATQAISSFGIVLVSGIFT 756
Cdd:TIGR00966 183 TRKTFTEVInLSINqtlsrtiNTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIV 237
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
258-330 |
1.46e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 41.51 E-value: 1.46e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1236136426 258 RDVSTLGIATLLGVFLLIVAVFRSLRPLLLSVLSIAIG---ALAGTVVTLLLFG-ELHLMTLVMSMSI-IGISADYTL 330
Cdd:pfam03176 142 RDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSlgaAQGLVAILAHILGiGLSTFALNLLVVLlIAVGTDYAL 219
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
640-773 |
1.49e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 42.15 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 640 LFAALAVIACGAMLRLGWRKGLISLVPSVLSLSCGLAVLAATgH------PVNLFSLLALVLVLGIGINYTL-FFSNPRG 712
Cdd:PRK12911 1240 LFGALGIILLYVSLRFEWRYAFSAICALIHDLLATCAVLVAL-HfflqkiQIDLQAIGALMTVLGYSLNNTLiIFDRIRE 1318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 713 -------TPL----TSMLAITLA--MMTTLLTLG---MLVFSATQAISSFGIVLVSGIFTAFL----LAP---LAMPDKK 769
Cdd:PRK12911 1319 drqeklfTPMpiliNDALQKTLGrtVMTTATTLSvllILLFVGGGSIFNFAFIMTIGILLGTLsslyIAPpllLFMVRKE 1398
|
....
gi 1236136426 770 ERKR 773
Cdd:PRK12911 1399 ERNS 1402
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
639-756 |
1.51e-03 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 40.28 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236136426 639 LLFAALAVIACGAMLRLGWRKGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGIGINYTL---------FFSN 709
Cdd:pfam02355 36 ALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLTIIGYSVNDTVvvfdrvrenLRKK 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1236136426 710 PRGTPLTSM-LAIT-------LAMMTTLLTLGMLVFSATQAISSFGIVLVSGIFT 756
Cdd:pfam02355 116 TRATLNEIMnLSINqtltrtiNTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIV 170
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
251-324 |
1.61e-03 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 42.01 E-value: 1.61e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1236136426 251 YASQQAKRDVSTLGIATLLGVFLLIVAVFRSLR-PLLlsVLSIAIGALAGTVVTLLLFGelhlMTLVMsMSIIGI 324
Cdd:COG0841 844 EEEQESFSSLGLAFLLALLLVYLVLAAQFESFIqPLI--ILLTVPLALIGALLGLLLTG----TPLNI-YSQIGL 911
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
254-309 |
7.60e-03 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 40.01 E-value: 7.60e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1236136426 254 QQAKRDVSTLGIATLLGVFLLIVAVFRSLRPLLLSVLSIAIgALAGTVVTLLLFGE 309
Cdd:COG3696 860 QRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPF-ALIGGVLALWLRGM 914
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
634-699 |
8.33e-03 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 39.59 E-value: 8.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236136426 634 TLLTGLLFAALAVIacgamLRLG-WRKGLISLVPSVLSLSCGLAVLAATGHPVNLFSLLALVLVLGI 699
Cdd:pfam00873 336 TLLEAIVLVILVMF-----LFLQnWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGL 397
|
|
| |
