|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
5-475 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 703.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:COG0469 3 RRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 VVY-PGDRVTFVTgEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKKGVNLP 163
Cdd:COG0469 83 VELkKGDTFTLTT-DDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVE-GDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 164 NTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKEnAGHEIPIIAKIEKPEALVNIDKIMAACNGIM 243
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEE-AGGRAPIIAKIEKPEAVENLDEIIEASDGIM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 244 VARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYP 323
Cdd:COG0469 240 VARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 324 VQVIQQMTRIIKSVEDSNLIQVPLITPFIRSLRYVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSHILIF 403
Cdd:COG0469 320 VEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1212708555 404 TSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKGMVNTLRVSEI 475
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
5-465 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 544.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:PRK05826 4 RRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEGK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 VVY-PGDRVTFVTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTnREDEVVAVVVQGGPLKSKKGVNLP 163
Cdd:PRK05826 84 ITLkTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEV-DGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 164 NTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIMAACNGIM 243
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPHAKIIAKIERAEAVDNIDEIIEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 244 VARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYP 323
Cdd:PRK05826 243 VARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 324 VQVIQQMTRIIKSVE---DSNLIQVPLITPFIRSLRYVTNTICFHAAKMAndtNAKVITSLTNSGYAAFRISSYRPNSHI 400
Cdd:PRK05826 323 VEAVEAMARICKGAEkefSINLSKHRLDRQFDRIDEAIAMSAMYAANHLK---GVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1212708555 401 LIFTSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKG 465
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-472 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 518.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 V-VYPGDRVTFVTGEP-FVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKKGVNL 162
Cdd:TIGR01064 81 VkLKKGDKVIITTDDIkGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVE-GDKVICEVLNGGTLKSKKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 163 PNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIMAACNGI 242
Cdd:TIGR01064 160 PGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 243 MVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKY 322
Cdd:TIGR01064 240 MVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 323 PVQVIQQMTRIIKSVEdSNLIQVPLITPFIRSL---RYVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSH 399
Cdd:TIGR01064 320 PVEAVQMMAKIAKEAE-KALAYLTNFNDRKNSDpkpSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAP 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1212708555 400 ILIFTSNKRILTQLNLLWGVTTFYYDRFVS-TDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKGMVNTLRV 472
Cdd:TIGR01064 399 IIAVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
5-475 |
5.71e-165 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 474.88 E-value: 5.71e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMED-- 82
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGgk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 83 DAVVYPGDRVTFVTGEPFV-GTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNREDEVVAVVVQGGPLKSKKGVN 161
Cdd:cd00288 82 DISLKAGDKFLVTTDPAAKkGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKTLVCEVLNGGVLGSRKGVN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 162 LPNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKEnAGHEIPIIAKIEKPEALVNIDKIMAACNG 241
Cdd:cd00288 162 LPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGE-KGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 242 IMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGK 321
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 322 YPVQVIQQMTRIIKSVEdsnliQVPLITPFIRSLRY-------VTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSY 394
Cdd:cd00288 321 YPVEAVKAMARICLEAE-----KALSHRVLFNEMRRltprptsTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKY 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 395 RPNSHILIFTSNKRILTQLNLLWGVTTFYYDRFV-----STDELIEDINHIANEKGYVDMGDIMISLVSMPMqGKGMVNT 469
Cdd:cd00288 396 RPNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPKpgwqeDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPV-GSGSTNT 474
|
....*.
gi 1212708555 470 LRVSEI 475
Cdd:cd00288 475 MRILTV 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-338 |
2.84e-129 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 379.02 E-value: 2.84e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 VVYP---GDRVTFVTGEPFVG--TKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNREDEVVAVVVQGGPLKSKKG 159
Cdd:pfam00224 82 KDIElkaGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKTLVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 160 VNLPNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKEnAGHEIPIIAKIEKPEALVNIDKIMAAC 239
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGE-AGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 240 NGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSV 319
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330
....*....|....*....
gi 1212708555 320 GKYPVQVIQQMTRIIKSVE 338
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAE 339
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
5-475 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 703.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:COG0469 3 RRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 VVY-PGDRVTFVTgEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKKGVNLP 163
Cdd:COG0469 83 VELkKGDTFTLTT-DDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVE-GDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 164 NTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKEnAGHEIPIIAKIEKPEALVNIDKIMAACNGIM 243
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEE-AGGRAPIIAKIEKPEAVENLDEIIEASDGIM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 244 VARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYP 323
Cdd:COG0469 240 VARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 324 VQVIQQMTRIIKSVEDSNLIQVPLITPFIRSLRYVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSHILIF 403
Cdd:COG0469 320 VEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1212708555 404 TSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKGMVNTLRVSEI 475
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
5-465 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 544.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:PRK05826 4 RRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEGK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 VVY-PGDRVTFVTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTnREDEVVAVVVQGGPLKSKKGVNLP 163
Cdd:PRK05826 84 ITLkTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEV-DGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 164 NTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIMAACNGIM 243
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPHAKIIAKIERAEAVDNIDEIIEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 244 VARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYP 323
Cdd:PRK05826 243 VARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 324 VQVIQQMTRIIKSVE---DSNLIQVPLITPFIRSLRYVTNTICFHAAKMAndtNAKVITSLTNSGYAAFRISSYRPNSHI 400
Cdd:PRK05826 323 VEAVEAMARICKGAEkefSINLSKHRLDRQFDRIDEAIAMSAMYAANHLK---GVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1212708555 401 LIFTSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKG 465
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-472 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 518.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 V-VYPGDRVTFVTGEP-FVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKKGVNL 162
Cdd:TIGR01064 81 VkLKKGDKVIITTDDIkGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVE-GDKVICEVLNGGTLKSKKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 163 PNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIMAACNGI 242
Cdd:TIGR01064 160 PGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 243 MVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKY 322
Cdd:TIGR01064 240 MVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 323 PVQVIQQMTRIIKSVEdSNLIQVPLITPFIRSL---RYVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSH 399
Cdd:TIGR01064 320 PVEAVQMMAKIAKEAE-KALAYLTNFNDRKNSDpkpSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAP 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1212708555 400 ILIFTSNKRILTQLNLLWGVTTFYYDRFVS-TDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKGMVNTLRV 472
Cdd:TIGR01064 399 IIAVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
5-454 |
1.57e-179 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 516.02 E-value: 1.57e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:PRK06354 8 RRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDGP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 V-VYPGDRVTfVTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNRED-EVVAVVVQGGPLKSKKGVNL 162
Cdd:PRK06354 88 IeLKTGDEFI-LTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADgELHCKVLVGGVLSNKKGVNF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 163 PNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIMAACNGI 242
Cdd:PRK06354 167 PGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNGKHIPIIAKIEKQEAIDNIDAILELCDGL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 243 MVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKY 322
Cdd:PRK06354 247 MVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGDY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 323 PVQVIQQMTRIIKSVEDSnLIQVPLITPFIRSLRYVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSHILI 402
Cdd:PRK06354 327 PVEAVQTMATIAVRIEKD-LPYRDILSKRPEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPILA 405
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1212708555 403 FTSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMI 454
Cdd:PRK06354 406 VTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVV 457
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-475 |
3.67e-167 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 480.19 E-value: 3.67e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 1 MLNTKKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVM 80
Cdd:PRK06247 1 MKRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 81 EDDAVVY-PGDRVTfVTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNREDeVVAVVVQGGPLKSKKG 159
Cdd:PRK06247 81 ADGKVQLaNGQTFR-LDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDD-VVCRVVEGGPVSDRKG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 160 VNLPNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAgheiPIIAKIEKPEALVNIDKIMAAC 239
Cdd:PRK06247 159 VSLPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGRV----PVMAKIEKPQAIDRLEAIVEAS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 240 NGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSV 319
Cdd:PRK06247 235 DAIMVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETAS 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 320 GKYPVQVIQQMTRIIKSVED----SNLIQVPLITPFIRslryVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYR 395
Cdd:PRK06247 315 GKYPVEAVRTMARIIRQVERdptyPPLIHAQRPQPEAT----KRDAISYAARDIAERLDLAALVAYTSSGDTALRAARER 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 396 PNSHILIFTSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKGMVNTLRVSEI 475
Cdd:PRK06247 391 PPLPILALTPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYI 470
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
5-475 |
5.71e-165 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 474.88 E-value: 5.71e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMED-- 82
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGgk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 83 DAVVYPGDRVTFVTGEPFV-GTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNREDEVVAVVVQGGPLKSKKGVN 161
Cdd:cd00288 82 DISLKAGDKFLVTTDPAAKkGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKTLVCEVLNGGVLGSRKGVN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 162 LPNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKEnAGHEIPIIAKIEKPEALVNIDKIMAACNG 241
Cdd:cd00288 162 LPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGE-KGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 242 IMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGK 321
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 322 YPVQVIQQMTRIIKSVEdsnliQVPLITPFIRSLRY-------VTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSY 394
Cdd:cd00288 321 YPVEAVKAMARICLEAE-----KALSHRVLFNEMRRltprptsTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKY 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 395 RPNSHILIFTSNKRILTQLNLLWGVTTFYYDRFV-----STDELIEDINHIANEKGYVDMGDIMISLVSMPMqGKGMVNT 469
Cdd:cd00288 396 RPNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPKpgwqeDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPV-GSGSTNT 474
|
....*.
gi 1212708555 470 LRVSEI 475
Cdd:cd00288 475 MRILTV 480
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
5-472 |
4.54e-145 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 423.70 E-value: 4.54e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMED-- 82
Cdd:PRK09206 2 KKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGgn 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 83 DAVVYPGDRVTFVTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKKGVNL 162
Cdd:PRK09206 82 DVSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAIT-GNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 163 PNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIMAACNGI 242
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 243 MVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKY 322
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 323 PVQVIQQMTRIIKSVeDSNLIQVPLITPFIRSLRyVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSHILI 402
Cdd:PRK09206 321 PLEAVSIMATICERT-DRVMNSRLESNNDNRKLR-ITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILA 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 403 FTSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMIsLVSMPMQGKGMVNTLRV 472
Cdd:PRK09206 399 LTTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVV-MVSGALVPSGTTNTASV 467
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-338 |
2.84e-129 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 379.02 E-value: 2.84e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDA 84
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 85 VVYP---GDRVTFVTGEPFVG--TKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNREDEVVAVVVQGGPLKSKKG 159
Cdd:pfam00224 82 KDIElkaGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKTLVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 160 VNLPNTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKEnAGHEIPIIAKIEKPEALVNIDKIMAAC 239
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGE-AGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 240 NGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSV 319
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330
....*....|....*....
gi 1212708555 320 GKYPVQVIQQMTRIIKSVE 338
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAE 339
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
31-472 |
8.62e-106 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 322.77 E-value: 8.62e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 31 VNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDDAVVYPGDRVTFVTGEPF---VGTKERA 107
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAfadKGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 108 YMNYKAFPQDVNPGERILLDDGKLIFEVESTNREDEVVAVVVQGGPLKSKKGVNLPNTKVSLPALTEKDVRDALFAISQE 187
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 188 VDWFALSFVRHPEDIQDLKELIKENaGHEIPIIAKIEKPEALVNIDKIMAACNGIMVARGDLGVEIPAEEVPLIQKELVH 267
Cdd:PTZ00300 161 VDMIFASFIRSAEQVGEVRKALGAK-GGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILIS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 268 KAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYPVQVIQQMTRIikSVEDSNLIQVPL 347
Cdd:PTZ00300 240 KCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARI--CLEAQSAVNEYV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 348 ITPFIRSLR----YVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSHILIFTSNKRILTQLNLLWGVTTFY 423
Cdd:PTZ00300 318 FFNSIKKLQpipmSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVF 397
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1212708555 424 YDrfvsTDELIEDINH---------IANEKGYVDMGDIMIsLVSMPMQGKGMVNTLRV 472
Cdd:PTZ00300 398 FD----AERLGHDEGKeqrvamgvgFAKSKGYVQSGDLMV-VVHADHKVKGYANQTRI 450
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-475 |
3.19e-104 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 320.56 E-value: 3.19e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 2 LNTKKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHT-AILADLQGPKLRVGVM 80
Cdd:PTZ00066 35 LRQKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARPNANlGILLDTKGPEIRTGFL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 81 EDDAVVY--PGDRVTFVTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKK 158
Cdd:PTZ00066 115 KNHKPITlkEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVH-DDYIITKVLNNATIGERK 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 159 GVNLPNTKVSLPALTEKDVRDAL-FAISQEVDWFALSFVRHPEDIQDLKELIKENAGHeIPIIAKIEKPEALVNIDKIMA 237
Cdd:PTZ00066 194 NMNLPGVKVELPVIGEKDKNDILnFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRH-IKIIPKIENIEGLINFDEILA 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 238 ACNGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGET 317
Cdd:PTZ00066 273 ESDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGET 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 318 SVGKYPVQVIQQMTRIIKSVEdsNLIQVPLI---------TPFirslrYVTNTICFHAAKMANDTNAKVITSLTNSGYAA 388
Cdd:PTZ00066 353 ANGKFPVEAVNIMAKICFEAE--TCIDYRVLyhaihlavpTPV-----SVQEAVARSAVETAEDINAKLIIALTETGNTA 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 389 FRISSYRPNSHILIFTSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINHIANEKGYVDMGDIMISLVSMPMQGKGMVN 468
Cdd:PTZ00066 426 RLISKYRPSCTILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSN 505
|
....*..
gi 1212708555 469 TLRVSEI 475
Cdd:PTZ00066 506 LMKVVKI 512
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
5-423 |
6.97e-103 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 319.57 E-value: 6.97e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 5 KKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHT-AILADLQGPKLRVGVMEDD 83
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQSKDNViAIMLDTKGPEVRSGDLPQP 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 84 AVVYPGDRVTFvTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKKGVNLP 163
Cdd:PLN02623 190 IMLEEGQEFTF-TIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKT-SDSVKCEVVDGGELKSRRHLNVR 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 164 NTKVSLPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKeNAGHEIPIIAKIEKPEALVNIDKIMAACNGIM 243
Cdd:PLN02623 268 GKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLK-SCNADIHVIVKIESADSIPNLHSIITASDGAM 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 244 VARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYP 323
Cdd:PLN02623 347 VARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFP 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 324 VQVIQQMTRIIKSVEDS--NLIQVPLITPFIRSlrYVTNTICFHAAKMANDTNAKVITsLTNSGYAAFRISSYRPNSHIL 401
Cdd:PLN02623 427 LKAVKVMHTVALRTEATlpEGTTPPNLGQAFKN--HMSEMFAFHATMMANTLGTSIIV-FTRTGFMAILLSHYRPSGTIF 503
|
410 420
....*....|....*....|..
gi 1212708555 402 IFTSNKRILTQLNLLWGVTTFY 423
Cdd:PLN02623 504 AFTNEKRIQQRLALYQGVCPIY 525
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-401 |
1.33e-97 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 303.44 E-value: 1.33e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 1 MLNTKKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVM 80
Cdd:PLN02461 17 GLRRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 81 EDDAVVY--PGDRVTFVTGEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNREDEVVAVVVQGGP-LKSK 157
Cdd:PLN02461 97 KDGKPVQlkQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEAGTVRCRCENSAmLGER 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 158 KGVNLPNTKVSLPALTEKDVRDAL-FAISQEVDWFALSFVRHPEDIQDLKELIKENAGHeIPIIAKIEKPEALVNIDKIM 236
Cdd:PLN02461 177 KNVNLPGVVVDLPTLTEKDKEDILqWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKS-ILLISKVENQEGLDNFDDIL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 237 AACNGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGE 316
Cdd:PLN02461 256 AESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGE 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 317 TSVGKYPVQVIQQMTRIIKSVEDS--------NLI-QVPLITPFIRSLryvtntiCFHAAKMANDTNAKVITSLTNSGYA 387
Cdd:PLN02461 336 TAAGAYPELAVKTMARICREAEASldygalfkEIMrSAPLPMSPLESL-------ASSAVRTANKVKASLIVVLTRGGTT 408
|
410
....*....|....
gi 1212708555 388 AFRISSYRPNSHIL 401
Cdd:PLN02461 409 ARLVAKYRPAVPIL 422
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
2-456 |
2.46e-93 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 292.42 E-value: 2.46e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 2 LNTKKTKIVATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVM- 80
Cdd:PLN02762 22 RSTRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDLg 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 81 -EDDAVVYPGDRVTFvTGEPFVGTKERAYM--NYKAFPQDVNPGERILLDDGKLIFEVestnredevvavVVQGGP-LKS 156
Cdd:PLN02762 102 gASSAKAEDGEEWTF-TVRKFDGSRPEFTIqvNYDGFAEDVKVGDELVVDGGMVRFEV------------IEKIGPdVKC 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 157 K---KGVNLPNTKVS--------------LPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENA-GHEIP 218
Cdd:PLN02762 169 KctdPGLLLPRANLTfwrdgslvrernamLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSrDSDIG 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 219 IIAKIEKPEALVNIDKIMAACNGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVN 298
Cdd:PLN02762 249 VIAKIESLDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVA 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 299 DVGNSVMDGADAVMLSGETSVGKYP---VQVIQQMT-RIIK-SVEDSNLIQVPLITPFIRSLRYVTNTICFHAAKMANDT 373
Cdd:PLN02762 329 DVSEAVRQRADALMLSGESAMGLYPekaLSVLRSVSlRMELwSREEKRHEALELPQLSSSLSDRISEEICNSAAKMANNL 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 374 NAKVITSLTNSGYAAFRISSYRPNSHILIFTSNKRILTQLNLLWGVTTFyydRFVSTDELIEDINH---IANEKGYVDMG 450
Cdd:PLN02762 409 GVDAIFVYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPF---RLDFSDDMESNLNKtfsLLKARGMIKSG 485
|
....*.
gi 1212708555 451 DIMISL 456
Cdd:PLN02762 486 DLVIAV 491
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
10-333 |
1.34e-87 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 272.59 E-value: 1.34e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 10 VATLGPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEhgfhTAILADLQGPKLRVGVMEDDAV-VYP 88
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS----IKILGDVQGPKIRLGEIKGEQItLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 89 GDRVTFVTgEPFVGTKERAYMNYKAFPQDVNPGERILLDDGKLIFEVESTNrEDEVVAVVVQGGPLKSKKGVNLPNTKVS 168
Cdd:PRK06739 82 GDSFILHT-QPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVS-TDKIETKVKTGGNISSHKGVNLPGAIVR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 169 LPALTEKDVRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIMAACNGIMVARGD 248
Cdd:PRK06739 160 LPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPNLIAKIETMEAIENFQDICKEADGIMIARGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 249 LGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYPVQVIQ 328
Cdd:PRK06739 240 LGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVS 319
|
....*
gi 1212708555 329 QMTRI 333
Cdd:PRK06739 320 TLRLV 324
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
7-401 |
2.14e-64 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 217.23 E-value: 2.14e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 7 TKIVATLGPATESPEVIKDMMAAGVNVFRINFS--HADY-----DDVRNRIKMIRQIneehgfhTAILADLQGPKLRVGV 79
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSwgDAEYhqetlENLKIAVKNTKKL-------CAVMLDTVGPELQVIN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 80 MEDDAVVY-PGDRVTFVTGEPFVGTKERAYMNYKAFPQDVNPGERILLddGKLIF----------EVESTNREDeVVAVV 148
Cdd:PLN02765 103 KTEKPISLkAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFV--GQYLFtgsettsvwlEVDEVKGDD-VVCTV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 149 ----VQGGPLKSkkgVNLPNTKVSLPALTEKDVRdalfAISQ-----EVDWFALSFVRHPEDIQDLKELIKENAGHEIPI 219
Cdd:PLN02765 180 knsaTLAGSLFT---LHVSQVRIDLPTLSEKDKE----VISTwgvpnKIDFLSLSYTRHAEDVREAREFLSSLGLSQTQI 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 220 IAKIEKPEALVNIDKIMAACNGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIaTQMMESMISSLTPTRAEVND 299
Cdd:PLN02765 253 FAKIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATD 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 300 VGNSVMDGADAVMLSGETSVGKYPVQVIQQMTRIIKSVE---DSNLIqvplitpFIRSLRYV------TNTICFHAAKMA 370
Cdd:PLN02765 332 VANAVLDGADAILLGAETLRGLYPVETISTVGRICAEAEkvfNQDLY-------FKKTVKYVgepmshLESIASSAVRAA 404
|
410 420 430
....*....|....*....|....*....|.
gi 1212708555 371 NDTNAKVITSLTNSGYAAFRISSYRPNSHIL 401
Cdd:PLN02765 405 IKVKASVIIVFTSSGRAARLIAKYRPTMPVL 435
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
3-313 |
1.55e-58 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 201.01 E-value: 1.55e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 3 NTKKTKIVATL-GPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVM- 80
Cdd:PRK08187 131 AARRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVa 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 81 --EDDAVVYPGDRVTFVTGEPFVGTKERAYMNYKAFPQ---DVNPGERILLDDGKLIFEVESTnREDEVVAVVVQGGP-- 153
Cdd:PRK08187 211 gpLGKTRLYTGDRLALVAQGPPRRIDEEHFQVTCTLPEilaRLAVGARVWIDDGKLGARVERV-GPGGALLEVTHARPkg 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 154 --LKSKKGVNLPNTKVSLPALTEKDvRDALFAISQEVDWFALSFVRHPEDIQDLKELIKENAGHEIP---IIAKIEKPEA 228
Cdd:PRK08187 290 lkLKPEKGLNFPDTALDLPALTEKD-RADLDFVARHADLVGYSFVQSPGDVEALQAALAARRPDDWRklgLVLKIETPRA 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 229 LVNI-DKIMAACN----GIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPVIIATQMMESMISSLTPTRAEVNDvgnS 303
Cdd:PRK08187 369 VANLpELIVQAAGrqpfGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTD---A 445
|
330
....*....|.
gi 1212708555 304 VMDG-ADAVML 313
Cdd:PRK08187 446 AMAArAECVML 456
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
7-313 |
1.39e-53 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 190.16 E-value: 1.39e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 7 TKIVATL-GPATESPEVIKDMMAAGVNVFRINFSHADYDDVRNRIKMIRQINEEHGFHTAILADLQGPKLRVGVMEDD-- 83
Cdd:PRK14725 141 TRIMVTLpTEAADDPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGPIAPGpr 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 84 ----------------------------------------------AVVYPGDRVTF--------------VTGEPFVGT 103
Cdd:PRK14725 221 viklrptrdalgrvltparlwltasespppspppgpvglpvdpewlARLEPGDELRFtdargkkrkltvteVDDEGVLAE 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 104 KER-AYM---------NYKAF---------------------------------------------PQ---DVNPGERIL 125
Cdd:PRK14725 301 GSQtAYLangtllrlgRHDSTrvgglppveqklrlkvgdrlvltrddapgdpaqgdapparisctlPEafrAARVGERVW 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 126 LDDGKLIFEVESTNrEDEVVAVVVQGGP----LKSKKGVNLPNTKVSLPALTEKDVRDALFaISQEVDWFALSFVRHPED 201
Cdd:PRK14725 381 FDDGKIGAVVVKVE-ADEVELRITHARPggskLKAGKGINLPDSHLPLPALTDKDLEDLAF-VAKHADIVALSFVRSPED 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 202 IQDLKELIKENAGHEIPIIAKIEKPEALVNIDKIM-----AACNGIMVARGDLGVEIPAEEVPLIQKELVHKAKSHHIPV 276
Cdd:PRK14725 459 VRLLLDALEKLGADDLGVVLKIETRRAFENLPRILleamrHPRFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPV 538
|
410 420 430
....*....|....*....|....*....|....*..
gi 1212708555 277 IIATQMMESMISSLTPTRAEVNDVGNSVMdgADAVML 313
Cdd:PRK14725 539 IWATQVLESLAKKGLPSRAEITDAAMALR--AECVML 573
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
274-472 |
1.45e-40 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 148.12 E-value: 1.45e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 274 IPVIIATQMMESMISSLTPTRAEVNDVGNSVMDGADAVMLSGETSVGKYPVQVIQQMTRIIKSVEDSNLIQVPLITPFIR 353
Cdd:COG3848 7 KPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQRVPRAKE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 354 SLRYVTNTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSHILIFTSNKRILTQLNLLWGVTTFYYDRFVSTDEL 433
Cdd:COG3848 87 SSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEESASTDEM 166
|
170 180 190
....*....|....*....|....*....|....*....
gi 1212708555 434 IEDINHIANEKGYVDMGDIMISLVSMPMQGKGMVNTLRV 472
Cdd:COG3848 167 FAVAVALALEAGLVKDGDLVVITAGVPVGVSGTTNLLKV 205
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
360-472 |
1.59e-34 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 125.29 E-value: 1.59e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 360 NTICFHAAKMANDTNAKVITSLTNSGYAAFRISSYRPNSHILIFTSNKRILTQLNLLWGVTTFYYDRFVSTDELIEDINH 439
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVK 80
|
90 100 110
....*....|....*....|....*....|...
gi 1212708555 440 IANEKGYVDMGDIMISLVSMPMQGKGMVNTLRV 472
Cdd:pfam02887 81 VAKEAGLVKKGDLVVITAGVPFGVSGTTNTLKV 113
|
|
| CitE |
COG2301 |
Citrate lyase beta subunit [Carbohydrate transport and metabolism]; |
178-277 |
2.43e-05 |
|
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
Pssm-ID: 441876 Cd Length: 288 Bit Score: 45.91 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212708555 178 RDALFAISQEVDWFALSFVRHPEDIQDLKELIK--ENAGHEIPIIAKIEKPEALVNIDKIMAACNGIMVAR-------GD 248
Cdd:COG2301 79 DDLAALVGAGLDGIVLPKVESAEDVRALAALLTelEAEGGSIPLMALIETARGLLNAAEIAAASPRVEALVfgaedlaAD 158
|
90 100 110
....*....|....*....|....*....|.
gi 1212708555 249 LGVEIPAEEVPL--IQKELVHKAKSHHIPVI 277
Cdd:COG2301 159 LGARRTRDGDELlyARSRIVLAARAAGLAAI 189
|
|
| |
