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Conserved domains on  [gi|1207638945|ref|WP_088002780|]
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transcriptional regulator [Bacillus pumilus]

Protein Classification

transcriptional regulator( domain architecture ID 11459460)

transcriptional regulator containing a PAS and a DNA-binding helix-turn-helix domain

Gene Ontology:  GO:0003677|GO:0140110

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
2-213 3.56e-85

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


:

Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 251.30  E-value: 3.56e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945   2 EHIKKLLESYIPLAKSTAKMFGPNCEVVIHDLTNPQASVMFTVNNHVTGREIGQSFDHLVKTVLQSEDFKE-DYLAGYTF 80
Cdd:COG2964     3 KEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPEHSIVAIANGHVSGRKVGDPITDLGLELLKDGAYEDpDVIGNYET 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945  81 VTEDKRKIRSSTSLIRDSKQKVIGAFCINFDIEALNQMQQFIDTFLTTQVEAQGAETTSNDDlenVEEIVDQLIQQIIQ- 159
Cdd:COG2964    83 RTKDGRLLKSSTIFIRDEKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASD---VEELIDEIIDEALAe 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1207638945 160 -NSVHPVMKRHEKIELIKFMDEKGIFLMKGSVEKVASMLGISKVTVYSYLDEIKN 213
Cdd:COG2964   160 vGKPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
2-213 3.56e-85

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 251.30  E-value: 3.56e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945   2 EHIKKLLESYIPLAKSTAKMFGPNCEVVIHDLTNPQASVMFTVNNHVTGREIGQSFDHLVKTVLQSEDFKE-DYLAGYTF 80
Cdd:COG2964     3 KEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPEHSIVAIANGHVSGRKVGDPITDLGLELLKDGAYEDpDVIGNYET 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945  81 VTEDKRKIRSSTSLIRDSKQKVIGAFCINFDIEALNQMQQFIDTFLTTQVEAQGAETTSNDDlenVEEIVDQLIQQIIQ- 159
Cdd:COG2964    83 RTKDGRLLKSSTIFIRDEKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASD---VEELIDEIIDEALAe 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1207638945 160 -NSVHPVMKRHEKIELIKFMDEKGIFLMKGSVEKVASMLGISKVTVYSYLDEIKN 213
Cdd:COG2964   160 vGKPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
8-121 1.96e-49

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 156.91  E-value: 1.96e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945   8 LESYIPLAKSTAKMFGPNCEVVIHDLTNPQASVMFTVNNHVTGREIGQSFDHLVKTVLQSEDFKE-DYLAGYTFVTEDKR 86
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLRDPEHSIVAIANGHVTGRKVGDPITDLALELLKQEEYEEkDYLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1207638945  87 KIRSSTSLIRDSKQKVIGAFCINFDIEALNQMQQF 121
Cdd:pfam08348  81 ILKSSTIFIRDEDGKIIGLLCINFDITALLAAQNA 115
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
2-213 3.56e-85

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 251.30  E-value: 3.56e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945   2 EHIKKLLESYIPLAKSTAKMFGPNCEVVIHDLTNPQASVMFTVNNHVTGREIGQSFDHLVKTVLQSEDFKE-DYLAGYTF 80
Cdd:COG2964     3 KEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPEHSIVAIANGHVSGRKVGDPITDLGLELLKDGAYEDpDVIGNYET 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945  81 VTEDKRKIRSSTSLIRDSKQKVIGAFCINFDIEALNQMQQFIDTFLTTQVEAQGAETTSNDDlenVEEIVDQLIQQIIQ- 159
Cdd:COG2964    83 RTKDGRLLKSSTIFIRDEKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASD---VEELIDEIIDEALAe 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1207638945 160 -NSVHPVMKRHEKIELIKFMDEKGIFLMKGSVEKVASMLGISKVTVYSYLDEIKN 213
Cdd:COG2964   160 vGKPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
8-121 1.96e-49

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 156.91  E-value: 1.96e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207638945   8 LESYIPLAKSTAKMFGPNCEVVIHDLTNPQASVMFTVNNHVTGREIGQSFDHLVKTVLQSEDFKE-DYLAGYTFVTEDKR 86
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLRDPEHSIVAIANGHVTGRKVGDPITDLALELLKQEEYEEkDYLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1207638945  87 KIRSSTSLIRDSKQKVIGAFCINFDIEALNQMQQF 121
Cdd:pfam08348  81 ILKSSTIFIRDEDGKIIGLLCINFDITALLAAQNA 115
HTH_22 pfam13309
HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding ...
149-209 3.43e-22

HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding domain.


Pssm-ID: 463841 [Multi-domain]  Cd Length: 63  Bit Score: 85.59  E-value: 3.43e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1207638945 149 IVDQLIQQIIQNSVHPV--MKRHEKIELIKFMDEKGIFLMKGSVEKVASMLGISKVTVYSYLD 209
Cdd:pfam13309   1 LLDSIIDEVLADVGKPParLTKEEKREIVRALDEKGAFLLKGAVEKVAKRLGVSRATVYNYLR 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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