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Conserved domains on  [gi|1194628167|ref|WP_085959879|]
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MULTISPECIES: IS3-like element IS1133 family transposase [Bacteria]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
8-372 1.30e-143

IS3 family transposase;


:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 411.96  E-value: 1.30e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167   8 EFKRDAVRIALTSGLTRRQVASDLSIGLSTLGKWIA------SISDETKIPTQDTDLLRENERLRKENRILREEREILKK 81
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKkyrgggEAADAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167  82 AGNIFRstKAVRFQFITDYRGSLSRSRICRLMGVTDRGLRAWKRRPPSLRQRRDLILLAHIREQHRLCLGSYGRPRMTEE 161
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 162 LKALGLQVGQRRVGRLMRQNNITVVRTRKFKR-TTDSHHTFNIAPNLLKQDFSASAPNQKWAGDITYVWTREGWVYLAVI 240
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 241 LDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIQHTDRGSQYCAHEYQKLLLKHQLLPSMSGKGNCFDNSAVE 320
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1194628167 321 SFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTLGWKSPVAFE 372
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
8-372 1.30e-143

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 411.96  E-value: 1.30e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167   8 EFKRDAVRIALTSGLTRRQVASDLSIGLSTLGKWIA------SISDETKIPTQDTDLLRENERLRKENRILREEREILKK 81
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKkyrgggEAADAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167  82 AGNIFRstKAVRFQFITDYRGSLSRSRICRLMGVTDRGLRAWKRRPPSLRQRRDLILLAHIREQHRLCLGSYGRPRMTEE 161
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 162 LKALGLQVGQRRVGRLMRQNNITVVRTRKFKR-TTDSHHTFNIAPNLLKQDFSASAPNQKWAGDITYVWTREGWVYLAVI 240
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 241 LDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIQHTDRGSQYCAHEYQKLLLKHQLLPSMSGKGNCFDNSAVE 320
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1194628167 321 SFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTLGWKSPVAFE 372
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
58-376 7.84e-98

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 293.21  E-value: 7.84e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167  58 LLRENERLRKENRILREEREILKKAGNIFRSTKAVRFQFITDYRGSLSRSRICRlmgvtdrglraWKRRPPSLRQRRDLI 137
Cdd:COG2801     4 EEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRR-----------RLRRPRSYRADEDAE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 138 LLAHIREQHRlCLGSYGRPRMTEELKALGLQVGQRRVGRLMRQNNITVVRTRKFKRTTDSHHTFNIAPNLLkqdFSASAP 217
Cdd:COG2801    73 LLERIKEIFA-ESPRYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FTATAP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 218 NQKWAGDITYVWTREGWVYLAVILDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIQHTDRGSQYCAHEYQKL 297
Cdd:COG2801   149 NQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQEL 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1194628167 298 LLKHQLLPSMSGKGNCFDNSAVESFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTLGWKSPVAFEKKAA 376
Cdd:COG2801   229 LKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQLA 306
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 113-373 1.05e-71

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 225.13  E-value: 1.05e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 113 MGVTDRGLRAWKRRP--PSLRQ---RRDLILLAHIREQHRLCLGSYGRPRMTEELKALGLQVGQRRVGRLMRQNNITVVR 187
Cdd:PHA02517    1 LGIAPSTYYRCQQQRhhPDKRRaraQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 188 TRKFKRTTDSHHTFNIaPNLLKQDFSASAPNQKWAGDITYVWTREGWVYLAVILDLYSRRVIGWATGDRLKQDLALRALN 267
Cdd:PHA02517   81 RGKKVRTTISRKAVAA-PDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 268 MALALRKPPPGCIQHTDRGSQYCAHEYQKLLLKHQLLPSMSGKGNCFDNSAVESFFKSLKAELIWRRHWQTRRDIEIAIF 347
Cdd:PHA02517  160 QALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATL 239

                         250       260
                  ....*....|....*....|....*.
gi 1194628167 348 EYInGFYNPRRRHSTLGWKSPVAFEK 373
Cdd:PHA02517  240 EWV-AWYNNRRLHERLGYTPPAEAEK 264
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 217-313 3.27e-24

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 3.27e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 217 PNQKWAGDITYVW--TREGWVYLAVILDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIqHTDRGSQYCAHEY 294
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLII-HSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1194628167 295 QKLLLKHQLLPSMSGKGNC 313
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 104-369 5.26e-18

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 83.02  E-value: 5.26e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 104 LSRSRICRLMGVTDRGLRAWK---------------RRPPSLRQRRDLILLAHI---REQHRLclgsyGRPRMTEELKAL 165
Cdd:NF033577   14 WSVREAARRFGISRKTVYKWLkryraggeeglidrsRRPHRSPRRTSPETEARIlalRRELRL-----GPRRIAYELERQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 166 GLQVGQRRVGRLMRQNNItvVRTRKFKRTTDShhtfniapnllKQDFSASAPNQKWAGDITYVWT--REGWVYLAVILDL 243
Cdd:NF033577   89 GPGVSRSTVHRILRRHGL--SRLRALDRKTGK-----------VKRYERAHPGELWHIDIKKLGRipDVGRLYLHTAIDD 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 244 YSRRVIGWATGDRLKQDlALRALNMALALRKPPPGCIQhTDRGSQYCAHEYQKLLLKHQL----------LPSMSGKgnc 313
Cdd:NF033577  156 HSRFAYAELYPDETAET-AADFLRRAFAEHGIPIRRVL-TDNGSEFRSRAHGFELALAELgiehrrtrpyHPQTNGK--- 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1194628167 314 fdnsaVESFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTLGWKSPV 369
Cdd:NF033577  231 -----VERFHRTLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPA 280
transpos_IS630 NF033545
IS630 family transposase;
104-196 7.23e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 38.01  E-value: 7.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 104 LSRSRICRLMGVTDRGLRAWKRR-----------------PPSLRQRRDLILLAHIREQHRLCLGSYGRPRMTEELKA-L 165
Cdd:NF033545   13 LSITEIAERLGVSRSTVYRWLKRfneggleglldkprpgrPRKLLSEQQAELLALLLEEPPEGAGHWTLRELAALLEEeF 92

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1194628167 166 GLQVGQRRVGRLMRQNNITVVRTRKFKRTTD 196
Cdd:NF033545   93 GVEYSRSTVRRLLKRLGLSPKKPRPRAPKQD 123
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
8-372 1.30e-143

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 411.96  E-value: 1.30e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167   8 EFKRDAVRIALTSGLTRRQVASDLSIGLSTLGKWIA------SISDETKIPTQDTDLLRENERLRKENRILREEREILKK 81
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKkyrgggEAADAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167  82 AGNIFRstKAVRFQFITDYRGSLSRSRICRLMGVTDRGLRAWKRRPPSLRQRRDLILLAHIREQHRLCLGSYGRPRMTEE 161
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 162 LKALGLQVGQRRVGRLMRQNNITVVRTRKFKR-TTDSHHTFNIAPNLLKQDFSASAPNQKWAGDITYVWTREGWVYLAVI 240
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 241 LDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIQHTDRGSQYCAHEYQKLLLKHQLLPSMSGKGNCFDNSAVE 320
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1194628167 321 SFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTLGWKSPVAFE 372
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
58-376 7.84e-98

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 293.21  E-value: 7.84e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167  58 LLRENERLRKENRILREEREILKKAGNIFRSTKAVRFQFITDYRGSLSRSRICRlmgvtdrglraWKRRPPSLRQRRDLI 137
Cdd:COG2801     4 EEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRR-----------RLRRPRSYRADEDAE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 138 LLAHIREQHRlCLGSYGRPRMTEELKALGLQVGQRRVGRLMRQNNITVVRTRKFKRTTDSHHTFNIAPNLLkqdFSASAP 217
Cdd:COG2801    73 LLERIKEIFA-ESPRYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FTATAP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 218 NQKWAGDITYVWTREGWVYLAVILDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIQHTDRGSQYCAHEYQKL 297
Cdd:COG2801   149 NQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQEL 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1194628167 298 LLKHQLLPSMSGKGNCFDNSAVESFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTLGWKSPVAFEKKAA 376
Cdd:COG2801   229 LKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQLA 306
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 113-373 1.05e-71

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 225.13  E-value: 1.05e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 113 MGVTDRGLRAWKRRP--PSLRQ---RRDLILLAHIREQHRLCLGSYGRPRMTEELKALGLQVGQRRVGRLMRQNNITVVR 187
Cdd:PHA02517    1 LGIAPSTYYRCQQQRhhPDKRRaraQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 188 TRKFKRTTDSHHTFNIaPNLLKQDFSASAPNQKWAGDITYVWTREGWVYLAVILDLYSRRVIGWATGDRLKQDLALRALN 267
Cdd:PHA02517   81 RGKKVRTTISRKAVAA-PDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 268 MALALRKPPPGCIQHTDRGSQYCAHEYQKLLLKHQLLPSMSGKGNCFDNSAVESFFKSLKAELIWRRHWQTRRDIEIAIF 347
Cdd:PHA02517  160 QALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATL 239

                         250       260
                  ....*....|....*....|....*.
gi 1194628167 348 EYInGFYNPRRRHSTLGWKSPVAFEK 373
Cdd:PHA02517  240 EWV-AWYNNRRLHERLGYTPPAEAEK 264
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 217-313 3.27e-24

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 3.27e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 217 PNQKWAGDITYVW--TREGWVYLAVILDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIqHTDRGSQYCAHEY 294
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLII-HSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1194628167 295 QKLLLKHQLLPSMSGKGNC 313
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 104-369 5.26e-18

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 83.02  E-value: 5.26e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 104 LSRSRICRLMGVTDRGLRAWK---------------RRPPSLRQRRDLILLAHI---REQHRLclgsyGRPRMTEELKAL 165
Cdd:NF033577   14 WSVREAARRFGISRKTVYKWLkryraggeeglidrsRRPHRSPRRTSPETEARIlalRRELRL-----GPRRIAYELERQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 166 GLQVGQRRVGRLMRQNNItvVRTRKFKRTTDShhtfniapnllKQDFSASAPNQKWAGDITYVWT--REGWVYLAVILDL 243
Cdd:NF033577   89 GPGVSRSTVHRILRRHGL--SRLRALDRKTGK-----------VKRYERAHPGELWHIDIKKLGRipDVGRLYLHTAIDD 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 244 YSRRVIGWATGDRLKQDlALRALNMALALRKPPPGCIQhTDRGSQYCAHEYQKLLLKHQL----------LPSMSGKgnc 313
Cdd:NF033577  156 HSRFAYAELYPDETAET-AADFLRRAFAEHGIPIRRVL-TDNGSEFRSRAHGFELALAELgiehrrtrpyHPQTNGK--- 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1194628167 314 fdnsaVESFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTLGWKSPV 369
Cdd:NF033577  231 -----VERFHRTLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPA 280
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
4-86 7.38e-17

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 74.96  E-value: 7.38e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167   4 KHSDEFKRDAVRIALTSGLTRRQVASDLSIGLSTLGKWI----ASISDETKIPTQDTDLLRENERLRKENRILREEREIL 79
Cdd:COG2963     7 RYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVrqyrEGGLGGFPGDGRTTPEQAEIRRLRKELRRLEMENDIL 86


                  ....*..
gi 1194628167  80 KKAGNIF 86
Cdd:COG2963    87 KKAAALL 93
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 133-191 2.25e-08

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 50.26  E-value: 2.25e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 133 RRDLILLAHIREQHRLCLGSYGRPRMTEELKALG-LQVGQRRVGRLMRQNNITVVRTRKF 191
Cdd:pfam13276   1 ELEDELLEAIREIFEESRGTYGYRRITAELRREGgIRVNRKRVARLMRELGLRARRRRKR 60
rve_2 pfam13333
Integrase core domain;
320-374 2.27e-08

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 49.95  E-value: 2.27e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1194628167 320 ESFFKSLKAELIWRRHWQTRRDIEIAIFEYINgFYNPRRRHSTlgwkSPVAFEKK 374
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIE-WYNNKRLKGL----SPVQYRNQ 50
rve_3 pfam13683
Integrase core domain;
305-368 3.07e-08

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 49.91  E-value: 3.07e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1194628167 305 PSMSGKGNCFDNSAVESFFKSLKAELIWRRHWQTRRDIEIAIFEYInGFYNPRRRHSTLGWKSP 368
Cdd:pfam13683   5 ISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWR-EDYNTERPHSSLGYRTP 67
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 4-70 9.13e-06

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 43.11  E-value: 9.13e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167   4 KHSDEFKRDAVRIALTSGLTRRQVASDLSIGLSTLGKWIASIS---DETKIPTQDTDLLRENERLRKENR 70
Cdd:pfam01527   6 RFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEggmGASPARPRLTALEEENRRLKRELA 75
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 73-292 4.52e-04

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 41.76  E-value: 4.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167  73 REEREILKKAGNIFRSTK-AVRFQFITDYRGSLSRSRICRLMGVTDRGLRAWKRR-----------------PPSLRQRR 134
Cdd:COG3415     7 EEERRDLEKLLRKTKDAReARRLRAVLLLAEGLSVREIAERLGVSRSTVYRWLKRyregglaglkdrprggrPSKLSDEQ 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 135 DLILLAHIREQHRLCLGSYGRPRMTEELKA-LGLQVGQRRVGRLMRQNNITVVRTRKFKRTTDSHhtfniAPNLLKQDFS 213
Cdd:COG3415    87 RERLLELLREKSPDQGSRWTLAELAELLEEeFGVEVSPSTVRRLLKRLGLSYKKPRPRAPKQDPE-----AVEKFKKELE 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1194628167 214 ASAPNQKWAGDITYVWTREGWVYLAVILDLYSRRVIGWATGDRLKQDLALRALNMALALRKPPPGCIQHTDRGSQYCAH 292
Cdd:COG3415   162 ALLAKPAKAEVAGVDEGDEIGALRRAAGGRLLAPGGRVRRTGASVRRGRALLFLALGLALGLRIGLTIDALLAGALLLF 240
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
 169-376 2.29e-03

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 39.33  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 169 VGQRRVGRLMRQNNITVVRTRKFKRTTDSHhTFNIApnllkqdfsASAPNQKWAGD-ITYVWTREGWVYLAVILDLYSRR 247
Cdd:PRK14702   48 INAKRVYRLMRQNALLLERKPAVPPSKRAH-TGRVA---------VKESNQRWCSDgFEFCCDNGERLRVTFALDCCDRE 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 248 VIGWA--TG---DRLKQDLALRALNMALALRKPPPGCIQHTDRGSQYCAHEYQKLLLKHQLLPSMSGKGNCFDNSAVESF 322
Cdd:PRK14702  118 ALHWAvtTGgfnSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESF 197

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1194628167 323 FKSLKAELIwrrHWQTRRDIEIAIFEYINGF--YNPRRRHSTLGWKSPVAFEKKAA 376
Cdd:PRK14702  198 VKTIKRDYI---SIMPKPDGLTAAKNLAEAFehYNEWHPHSALGYRSPREYLRQRA 250
transpos_IS630 NF033545
IS630 family transposase;
104-196 7.23e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 38.01  E-value: 7.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194628167 104 LSRSRICRLMGVTDRGLRAWKRR-----------------PPSLRQRRDLILLAHIREQHRLCLGSYGRPRMTEELKA-L 165
Cdd:NF033545   13 LSITEIAERLGVSRSTVYRWLKRfneggleglldkprpgrPRKLLSEQQAELLALLLEEPPEGAGHWTLRELAALLEEeF 92

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1194628167 166 GLQVGQRRVGRLMRQNNITVVRTRKFKRTTD 196
Cdd:NF033545   93 GVEYSRSTVRRLLKRLGLSPKKPRPRAPKQD 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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