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Conserved domains on  [gi|1184699467|ref|WP_085258819|]
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thioester domain-containing protein [Mycobacterium saskatchewanense]

Protein Classification

thioester domain-containing protein( domain architecture ID 10024214)

thioester domain-containing protein is characterized by intramolecular cross-links in structurally conserved thioester, isopeptide, and ester domains (TIE proteins); may be a surface-associated protein that mediates covalent host binding

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TQXA_dom TIGR03934
TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide ...
 102-155 3.22e-10

TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide in an almost invariant TQxA[VI]W motif. This domain occurs in surface-expressed proteins of Gram-positive bacteria, many of which are anchored by LPXTG-containing sortase target domains. Numerous members of this family have domains pfam05738 (Cna protein B-type domain) and pfam08341 (fibronectin-binding protein signal sequence).


:

Pssm-ID: 274864 [Multi-domain]  Cd Length: 42  Bit Score: 54.95  E-value: 3.22e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1184699467 102 QVDWILRHSFPMRSTAALsqqlraaghplgkANISEHEAIAATQAAIWHFTNGL 155
Cdd:TIGR03934   1 KILWILANGYPNKSNGEL-------------GGLTEEEARAVTQLAIWYFTDGL 41
 
Name Accession Description Interval E-value
TQXA_dom TIGR03934
TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide ...
 102-155 3.22e-10

TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide in an almost invariant TQxA[VI]W motif. This domain occurs in surface-expressed proteins of Gram-positive bacteria, many of which are anchored by LPXTG-containing sortase target domains. Numerous members of this family have domains pfam05738 (Cna protein B-type domain) and pfam08341 (fibronectin-binding protein signal sequence).


Pssm-ID: 274864 [Multi-domain]  Cd Length: 42  Bit Score: 54.95  E-value: 3.22e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1184699467 102 QVDWILRHSFPMRSTAALsqqlraaghplgkANISEHEAIAATQAAIWHFTNGL 155
Cdd:TIGR03934   1 KILWILANGYPNKSNGEL-------------GGLTEEEARAVTQLAIWYFTDGL 41
TED pfam08341
Thioester domain; This domain is found near the N-terminus of a variety of bacterial surface ...
 67-154 2.65e-07

Thioester domain; This domain is found near the N-terminus of a variety of bacterial surface proteins and pili. This domain contains an unusual covalent ester bond between a conserved cysteine and glutamine residue.


Pssm-ID: 462437 [Multi-domain]  Cd Length: 105  Bit Score: 48.77  E-value: 2.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184699467  67 AYSLDFTGVAPSHPSRYALGTWAALPHLSTRGyeaQVDWILRHSFPMRSTAalsqqlraaghPLGKANISEHEAIAATQA 146
Cdd:pfam08341   2 AYCIEPGKGFPSGGDGTASSETRLTLYKDNAD---KINWILYNGYPNKSGL-----------SEELGGLTDDDAYAATQA 67


                  ....*...
gi 1184699467 147 AIWHFTNG 154
Cdd:pfam08341  68 AIWHFTDG 75
 
Name Accession Description Interval E-value
TQXA_dom TIGR03934
TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide ...
 102-155 3.22e-10

TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide in an almost invariant TQxA[VI]W motif. This domain occurs in surface-expressed proteins of Gram-positive bacteria, many of which are anchored by LPXTG-containing sortase target domains. Numerous members of this family have domains pfam05738 (Cna protein B-type domain) and pfam08341 (fibronectin-binding protein signal sequence).


Pssm-ID: 274864 [Multi-domain]  Cd Length: 42  Bit Score: 54.95  E-value: 3.22e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1184699467 102 QVDWILRHSFPMRSTAALsqqlraaghplgkANISEHEAIAATQAAIWHFTNGL 155
Cdd:TIGR03934   1 KILWILANGYPNKSNGEL-------------GGLTEEEARAVTQLAIWYFTDGL 41
TED pfam08341
Thioester domain; This domain is found near the N-terminus of a variety of bacterial surface ...
 67-154 2.65e-07

Thioester domain; This domain is found near the N-terminus of a variety of bacterial surface proteins and pili. This domain contains an unusual covalent ester bond between a conserved cysteine and glutamine residue.


Pssm-ID: 462437 [Multi-domain]  Cd Length: 105  Bit Score: 48.77  E-value: 2.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184699467  67 AYSLDFTGVAPSHPSRYALGTWAALPHLSTRGyeaQVDWILRHSFPMRSTAalsqqlraaghPLGKANISEHEAIAATQA 146
Cdd:pfam08341   2 AYCIEPGKGFPSGGDGTASSETRLTLYKDNAD---KINWILYNGYPNKSGL-----------SEELGGLTDDDAYAATQA 67


                  ....*...
gi 1184699467 147 AIWHFTNG 154
Cdd:pfam08341  68 AIWHFTDG 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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