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Conserved domains on  [gi|1180338993|ref|WP_083857796|]
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MULTISPECIES: HEPN domain-containing protein [Caldilinea]

Protein Classification

HEPN domain-containing protein( domain architecture ID 10006209)

HEPN (higher eukarytoes and prokaryotes nucleotide)-binding domain-containing protein may be involved in nucleotide binding; similar to Thermotoga maritima HEPN domain protein (TM0613)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HEPN COG2250
HEPN domain protein, predicted toxin of MNT-HEPN system [Defense mechanisms];
5-62 2.15e-12

HEPN domain protein, predicted toxin of MNT-HEPN system [Defense mechanisms];


:

Pssm-ID: 441851  Cd Length: 121  Bit Score: 56.88  E-value: 2.15e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1180338993   5 SRRIVDAGRILDRFYIPTRYPNGFADGipADYYTADDCQTAIGCAETIVRFCADRLSQ 62
Cdd:COG2250    66 PEELRDLLRLLDKAYIPARYPDALPEG--PEEYTREEAEEALELAEEVLEFVEKLLKE 121
 
Name Accession Description Interval E-value
HEPN COG2250
HEPN domain protein, predicted toxin of MNT-HEPN system [Defense mechanisms];
5-62 2.15e-12

HEPN domain protein, predicted toxin of MNT-HEPN system [Defense mechanisms];


Pssm-ID: 441851  Cd Length: 121  Bit Score: 56.88  E-value: 2.15e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1180338993   5 SRRIVDAGRILDRFYIPTRYPNGFADGipADYYTADDCQTAIGCAETIVRFCADRLSQ 62
Cdd:COG2250    66 PEELRDLLRLLDKAYIPARYPDALPEG--PEEYTREEAEEALELAEEVLEFVEKLLKE 121
HEPN pfam05168
HEPN domain;
5-56 1.51e-08

HEPN domain;


Pssm-ID: 398711  Cd Length: 117  Bit Score: 46.85  E-value: 1.51e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1180338993   5 SRRIVDAGRILDRFYIPTRYPngfadgiPADYYTADDCQTAIGCAETIVRFC 56
Cdd:pfam05168  70 PEELREILDELEKAYIESRYP-------DADEGTEEDAEEALKDAEEILELV 114
HEPN smart00748
Higher Eukarytoes and Prokaryotes Nucleotide-binding domain;
6-52 3.91e-08

Higher Eukarytoes and Prokaryotes Nucleotide-binding domain;


Pssm-ID: 214800  Cd Length: 113  Bit Score: 45.75  E-value: 3.91e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1180338993    6 RRIVDAGRILDRFYIPTRYPNgfaDGIPADYYTADDCQTAIGCAETI 52
Cdd:smart00748  70 DEIRECLNLLEEAYIKSRYPD---AGEPLEWYTKEDAEELLKCAEEI 113
 
Name Accession Description Interval E-value
HEPN COG2250
HEPN domain protein, predicted toxin of MNT-HEPN system [Defense mechanisms];
5-62 2.15e-12

HEPN domain protein, predicted toxin of MNT-HEPN system [Defense mechanisms];


Pssm-ID: 441851  Cd Length: 121  Bit Score: 56.88  E-value: 2.15e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1180338993   5 SRRIVDAGRILDRFYIPTRYPNGFADGipADYYTADDCQTAIGCAETIVRFCADRLSQ 62
Cdd:COG2250    66 PEELRDLLRLLDKAYIPARYPDALPEG--PEEYTREEAEEALELAEEVLEFVEKLLKE 121
HEPN pfam05168
HEPN domain;
5-56 1.51e-08

HEPN domain;


Pssm-ID: 398711  Cd Length: 117  Bit Score: 46.85  E-value: 1.51e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1180338993   5 SRRIVDAGRILDRFYIPTRYPngfadgiPADYYTADDCQTAIGCAETIVRFC 56
Cdd:pfam05168  70 PEELREILDELEKAYIESRYP-------DADEGTEEDAEEALKDAEEILELV 114
HEPN smart00748
Higher Eukarytoes and Prokaryotes Nucleotide-binding domain;
6-52 3.91e-08

Higher Eukarytoes and Prokaryotes Nucleotide-binding domain;


Pssm-ID: 214800  Cd Length: 113  Bit Score: 45.75  E-value: 3.91e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1180338993    6 RRIVDAGRILDRFYIPTRYPNgfaDGIPADYYTADDCQTAIGCAETI 52
Cdd:smart00748  70 DEIRECLNLLEEAYIKSRYPD---AGEPLEWYTKEDAEELLKCAEEI 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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