|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-468 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 760.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQELKVGDTFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLPG 160
Cdd:COG0469 82 PVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 161 VAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDGIMVA 240
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 241 RGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYPIE 320
Cdd:COG0469 242 RGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPVE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 321 TVRTMAAIIESTEENGGER--IASIPGYFASDRAGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAFTP 398
Cdd:COG0469 322 AVETMARIAEEAEKSLDYRriLDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALTP 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 399 LETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRIHEV 468
Cdd:COG0469 402 NERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
2-471 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 620.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDGP 81
Cdd:PRK06247 5 RRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 82 QELKVGDTFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLPGV 161
Cdd:PRK06247 85 VQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLPGT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 162 AVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEImdeMGKRIPVIAKIEKPQAVEALEEIVEAFDGIMVAR 241
Cdd:PRK06247 165 VLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKI---IGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVAR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 242 GDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYPIET 321
Cdd:PRK06247 242 GDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVEA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 322 VRTMAAIIESTEENGGER-IASIPGYFA-SDRAGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAFTPL 399
Cdd:PRK06247 322 VRTMARIIRQVERDPTYPpLIHAQRPQPeATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTPN 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1175903992 400 ETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRIHEVGDE 471
Cdd:PRK06247 402 PETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYIGED 473
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-465 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 545.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDGP 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 82 QELKVGDTFTITTRD--VPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLP 159
Cdd:TIGR01064 81 VKLKKGDKVIITTDDikGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 160 GVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMG-KRIPVIAKIEKPQAVEALEEIVEAFDGIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 239 VARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 319 IETVRTMAAIIESTEENGGERIASIPGYFASDR----AGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPML 394
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKpstiTEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1175903992 395 AFTPLETTRRRLALSWGIQTYRVPE-VQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRI 465
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-468 |
8.28e-171 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 489.52 E-value: 8.28e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQ-ELKVGDTFTITTRD--VPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSD-TDVVTRVEVPGVVSDHKGL 156
Cdd:cd00288 81 KDiSLKAGDKFLVTTDPaaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDdKTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 157 NLPGVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDG 236
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 237 IMVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGA 316
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 317 YPIETVRTMAAIIESTeenggERIASIPGYFASDRAG---------VICDAAARIAEHMDARYLVTFTQSGTSARLLSRM 387
Cdd:cd00288 321 YPVEAVKAMARICLEA-----EKALSHRVLFNEMRRLtprptstteAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKY 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 388 RRPIPMLAFTPLETTRRRLALSWGI--QTYRVPEVQHTDDMVWQLDQVVQSSR---LADIGEQLVIVAGMPPGIpGSSNM 462
Cdd:cd00288 396 RPNAPIIAVTRNEQTARQLHLYRGVypVLFEEPKPGWQEDTDARLKAAVNVAKekgLLKKGDLVVVVQGWPVGS-GSTNT 474
|
....*.
gi 1175903992 463 LRIHEV 468
Cdd:cd00288 475 MRILTV 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-333 |
3.61e-144 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 416.77 E-value: 3.61e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQ--ELKVGDTFTITTRDV---PGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEV-SDTDVVTRVEVPGVVSDHK 154
Cdd:pfam00224 81 KKdiELKAGDEMIVSTDAKykgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKdDDKTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 155 GLNLPGVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAF 234
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 235 DGIMVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSV 314
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330
....*....|....*....
gi 1175903992 315 GAYPIETVRTMAAIIESTE 333
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAE 339
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-468 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 760.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQELKVGDTFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLPG 160
Cdd:COG0469 82 PVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 161 VAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDGIMVA 240
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 241 RGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYPIE 320
Cdd:COG0469 242 RGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPVE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 321 TVRTMAAIIESTEENGGER--IASIPGYFASDRAGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAFTP 398
Cdd:COG0469 322 AVETMARIAEEAEKSLDYRriLDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALTP 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 399 LETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRIHEV 468
Cdd:COG0469 402 NERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
2-471 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 620.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDGP 81
Cdd:PRK06247 5 RRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 82 QELKVGDTFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLPGV 161
Cdd:PRK06247 85 VQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLPGT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 162 AVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEImdeMGKRIPVIAKIEKPQAVEALEEIVEAFDGIMVAR 241
Cdd:PRK06247 165 VLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKI---IGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVAR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 242 GDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYPIET 321
Cdd:PRK06247 242 GDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVEA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 322 VRTMAAIIESTEENGGER-IASIPGYFA-SDRAGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAFTPL 399
Cdd:PRK06247 322 VRTMARIIRQVERDPTYPpLIHAQRPQPeATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTPN 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1175903992 400 ETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRIHEVGDE 471
Cdd:PRK06247 402 PETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYIGED 473
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-458 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 568.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQELKVGDTFTITT-RDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLP 159
Cdd:PRK05826 83 KITLKTGDKFTLDTdQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 160 GVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMG-KRIPVIAKIEKPQAVEALEEIVEAFDGIM 238
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGcPHAKIIAKIERAEAVDNIDEIIEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 239 VARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYP 318
Cdd:PRK05826 243 VARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 319 IETVRTMAAIIESTEEnggERIASIPGYFASDRAGVICDA----AARIAEH-MDARYLVTFTQSGTSARLLSRMRRPIPM 393
Cdd:PRK05826 323 VEAVEAMARICKGAEK---EFSINLSKHRLDRQFDRIDEAiamsAMYAANHlKGVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1175903992 394 LAFTPLETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPG 458
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-465 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 545.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDGP 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 82 QELKVGDTFTITTRD--VPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLP 159
Cdd:TIGR01064 81 VKLKKGDKVIITTDDikGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 160 GVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMG-KRIPVIAKIEKPQAVEALEEIVEAFDGIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 239 VARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 319 IETVRTMAAIIESTEENGGERIASIPGYFASDR----AGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPML 394
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKpstiTEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1175903992 395 AFTPLETTRRRLALSWGIQTYRVPE-VQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRI 465
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-477 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 519.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:PRK06354 7 MRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQELKVGDTFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEV--SDTDVVTRVEVPGVVSDHKGLNL 158
Cdd:PRK06354 87 PIELKTGDEFILTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVdkADGELHCKVLVGGVLSNKKGVNF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 159 PGVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDE-MGKRIPVIAKIEKPQAVEALEEIVEAFDGI 237
Cdd:PRK06354 167 PGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEhNGKHIPIIAKIEKQEAIDNIDAILELCDGL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 238 MVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAY 317
Cdd:PRK06354 247 MVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGDY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 318 PIETVRTMAAIIESTEENGGER-IASIPGYFASDRAGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAF 396
Cdd:PRK06354 327 PVEAVQTMATIAVRIEKDLPYRdILSKRPEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPILAV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 397 TPLETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRIHEVGDEADYAI 476
Cdd:PRK06354 407 TPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLVGESGSTDLMKVHVVGAVVAKGQ 486
|
.
gi 1175903992 477 G 477
Cdd:PRK06354 487 G 487
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-468 |
8.28e-171 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 489.52 E-value: 8.28e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQ-ELKVGDTFTITTRD--VPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSD-TDVVTRVEVPGVVSDHKGL 156
Cdd:cd00288 81 KDiSLKAGDKFLVTTDPaaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDdKTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 157 NLPGVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDG 236
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 237 IMVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGA 316
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 317 YPIETVRTMAAIIESTeenggERIASIPGYFASDRAG---------VICDAAARIAEHMDARYLVTFTQSGTSARLLSRM 387
Cdd:cd00288 321 YPVEAVKAMARICLEA-----EKALSHRVLFNEMRRLtprptstteAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKY 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 388 RRPIPMLAFTPLETTRRRLALSWGI--QTYRVPEVQHTDDMVWQLDQVVQSSR---LADIGEQLVIVAGMPPGIpGSSNM 462
Cdd:cd00288 396 RPNAPIIAVTRNEQTARQLHLYRGVypVLFEEPKPGWQEDTDARLKAAVNVAKekgLLKKGDLVVVVQGWPVGS-GSTNT 474
|
....*.
gi 1175903992 463 LRIHEV 468
Cdd:cd00288 475 MRILTV 480
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
1-451 |
2.12e-151 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 439.87 E-value: 2.12e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQ-ELKVGDTFTITT-RDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNL 158
Cdd:PRK09206 81 NDvSLKAGQTFTFTTdKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 159 PGVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEM-GKRIPVIAKIEKPQAVEALEEIVEAFDGI 237
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHgGENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 238 MVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAY 317
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 318 PIETVRTMAAIIESTEENGGERIASIPGYFASDRAGVICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAFT 397
Cdd:PRK09206 321 PLEAVSIMATICERTDRVMNSRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILALT 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 1175903992 398 PLETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAG 451
Cdd:PRK09206 401 TNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSG 454
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-333 |
3.61e-144 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 416.77 E-value: 3.61e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQ--ELKVGDTFTITTRDV---PGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEV-SDTDVVTRVEVPGVVSDHK 154
Cdd:pfam00224 81 KKdiELKAGDEMIVSTDAKykgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKdDDKTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 155 GLNLPGVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAF 234
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 235 DGIMVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSV 314
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330
....*....|....*....
gi 1175903992 315 GAYPIETVRTMAAIIESTE 333
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAE 339
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-465 |
1.55e-125 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 375.25 E-value: 1.55e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRA-VAVLVDLQGPKIRLETFQDG 80
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARPNAnLGILLDTKGPEIRTGFLKNH 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 -PQELKVGDTFTITTR-DVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNL 158
Cdd:PTZ00066 118 kPITLKEGQTLKITTDyTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMNL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 159 PGVAVSVPALSEKDKED-LRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDGI 237
Cdd:PTZ00066 198 PGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDGI 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 238 MVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAY 317
Cdd:PTZ00066 278 MVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGKF 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 318 PIETVRTMAAIIESTEENG------GERIASIPGYFASDRAgvICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPI 391
Cdd:PTZ00066 358 PVEAVNIMAKICFEAETCIdyrvlyHAIHLAVPTPVSVQEA--VARSAVETAEDINAKLIIALTETGNTARLISKYRPSC 435
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1175903992 392 PMLAFTPLETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVVQSSRLADIGEQLVIVAGMPPGIPGSSNMLRI 465
Cdd:PTZ00066 436 TILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNLMKV 509
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
3-394 |
1.64e-113 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 344.27 E-value: 1.64e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 3 RAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG-P 81
Cdd:PLN02461 22 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGkP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 82 QELKVGDTFTITTR-DVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVE--VSDTDVVTRVEVPGVVSDHKGLNL 158
Cdd:PLN02461 102 VQLKQGQEITITTDySIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLScdVEAGTVRCRCENSAMLGERKNVNL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 159 PGVAVSVPALSEKDKED-LRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDGI 237
Cdd:PLN02461 182 PGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDILAESDAF 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 238 MVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAY 317
Cdd:PLN02461 262 MVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAY 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 318 PIETVRTMAAII---ESTEENGGE-----RIASIP----GYFASdragvicdAAARIAEHMDARYLVTFTQSGTSARLLS 385
Cdd:PLN02461 342 PELAVKTMARICreaEASLDYGALfkeimRSAPLPmsplESLAS--------SAVRTANKVKASLIVVLTRGGTTARLVA 413
|
....*....
gi 1175903992 386 RMRRPIPML 394
Cdd:PLN02461 414 KYRPAVPIL 422
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
1-426 |
3.35e-103 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 317.84 E-value: 3.35e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 1 MRRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFqDG 80
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDL-GG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQELKVGD----TFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGL 156
Cdd:PLN02762 103 ASSAKAEDgeewTFTVRKFDGSRPEFTIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPGLLLPRANL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 157 NL--PGVAVS-----VPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMD--EMGKRIPVIAKIEKPQAVEAL 227
Cdd:PLN02762 183 TFwrDGSLVRernamLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAarSRDSDIGVIAKIESLDSLKNL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 228 EEIVEAFDGIMVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVM 307
Cdd:PLN02762 263 EEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRADALM 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 308 LSGETSVGAYP---IETVRTMAAIIE--STEENggeRIASIP----GYFASDR-AGVICDAAARIAEHMDARYLVTFTQS 377
Cdd:PLN02762 343 LSGESAMGLYPekaLSVLRSVSLRMElwSREEK---RHEALElpqlSSSLSDRiSEEICNSAAKMANNLGVDAIFVYTKH 419
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1175903992 378 GTSARLLSRMRRPIPMLAFTPLETTRRRLALSWGIQTYRVPEvqhTDDM 426
Cdd:PLN02762 420 GHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDF---SDDM 465
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
7-333 |
4.50e-97 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 296.47 E-value: 4.50e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 7 VCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATsgraVAVLVDLQGPKIRLETFQDGPQELKV 86
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS----IKILGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 87 GDTFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNLPGVAVSVP 166
Cdd:PRK06739 82 GDSFILHTQPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 167 ALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIP-VIAKIEKPQAVEALEEIVEAFDGIMVARGDLG 245
Cdd:PRK06739 162 AITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPnLIAKIETMEAIENFQDICKEADGIMIARGDLG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 246 VEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYPIETVRTM 325
Cdd:PRK06739 242 VELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTL 321
|
....*...
gi 1175903992 326 AAIIESTE 333
Cdd:PRK06739 322 RLVSEFAE 329
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
28-414 |
3.48e-96 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 297.73 E-value: 3.48e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 28 MDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDGPQELKVGDTFTITTRDV---PGTKELV 104
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAfadKGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 105 GTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVT-RVEVPGVVSDHKGLNLPGVAVSVPALSEKDKEDLRWAIQMD 183
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQTLKcTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 184 ADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDGIMVARGDLGVEMPLEAVPLVQKRAIEL 263
Cdd:PTZ00300 161 VDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 264 ARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYPIETVRTMA--------AIIESTEEN 335
Cdd:PTZ00300 241 CNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMAricleaqsAVNEYVFFN 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1175903992 336 GGERIASIPgyFASDRAgvICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAFTPLETTRRRLALSWGIQT 414
Cdd:PTZ00300 321 SIKKLQPIP--MSAEEA--VCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVES 395
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
2-425 |
3.29e-89 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 283.74 E-value: 3.29e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATS-GRAVAVLVDLQGPKIRletFQDG 80
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQSkDNVIAIMLDTKGPEVR---SGDL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQE--LKVGDTFTITTRDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDVVTRVEVPGVVSDHKGLNL 158
Cdd:PLN02623 187 PQPimLEEGQEFTFTIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNV 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 159 PGVAVSVPALSEKDKEDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGKRIPVIAKIEKPQAVEALEEIVEAFDGIM 238
Cdd:PLN02623 267 RGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITASDGAM 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 239 VARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANAILDGADAVMLSGETSVGAYP 318
Cdd:PLN02623 347 VARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFP 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 319 IETVRTMAAIIESTEEN--GGERIASIPGYFASDRAGVICDAAARIAEHMDARYLVtFTQSGTSARLLSRMRRPIPMLAF 396
Cdd:PLN02623 427 LKAVKVMHTVALRTEATlpEGTTPPNLGQAFKNHMSEMFAFHATMMANTLGTSIIV-FTRTGFMAILLSHYRPSGTIFAF 505
|
410 420
....*....|....*....|....*....
gi 1175903992 397 TPLETTRRRLALSWGIQTYRvpeVQHTDD 425
Cdd:PLN02623 506 TNEKRIQQRLALYQGVCPIY---MQFSDD 531
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
5-396 |
1.29e-82 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 264.99 E-value: 1.29e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 5 KIVCTIGPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDGPQEL 84
Cdd:PLN02765 31 KIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPISL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 85 KVGDTFTITT-RDVPGTKELVGTTFKGLPGDCAPGDRLLI--------DDGNVAVRVVEVSDTDVVTRVEVPGVVSdhkG 155
Cdd:PLN02765 111 KAGNTVTLTPdQSKEASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKNSATLA---G 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 156 LNLP----GVAVSVPALSEKDKEDLR-WAIQMDADFIALSFVRSAHDIDDVHEIMDEMG-KRIPVIAKIEKPQAVEALEE 229
Cdd:PLN02765 188 SLFTlhvsQVRIDLPTLSEKDKEVIStWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFAKIENVEGLTHFDE 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 230 IVEAFDGIMVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVaTQVMDSMIKNPRPTRAEASDCANAILDGADAVMLS 309
Cdd:PLN02765 268 ILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILLG 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 310 GETSVGAYPIETVRTMAAIIESteengGERIASIPGYFASDRAGV---------ICDAAARIAEHMDARYLVTFTQSGTS 380
Cdd:PLN02765 347 AETLRGLYPVETISTVGRICAE-----AEKVFNQDLYFKKTVKYVgepmshlesIASSAVRAAIKVKASVIIVFTSSGRA 421
|
410
....*....|....*.
gi 1175903992 381 ARLLSRMRRPIPMLAF 396
Cdd:PLN02765 422 ARLIAKYRPTMPVLSV 437
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
2-308 |
8.12e-58 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 198.70 E-value: 8.12e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTI-GPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETF--Q 78
Cdd:PRK08187 133 RRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVagP 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 79 DGPQELKVGDTFTITT----RDVPGTKELVGTTFKGLPGDCAPGDRLLIDDGNVAVRVVEVSDTDV---VTRVEVPGV-V 150
Cdd:PRK08187 213 LGKTRLYTGDRLALVAqgppRRIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGAlleVTHARPKGLkL 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 151 SDHKGLNLPGVAVSVPALSEKDKEDLRWAIQmDADFIALSFVRSAhdiDDVHEIMDEMGKRIP-------VIAKIEKPQA 223
Cdd:PRK08187 293 KPEKGLNFPDTALDLPALTEKDRADLDFVAR-HADLVGYSFVQSP---GDVEALQAALAARRPddwrklgLVLKIETPRA 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 224 VEALEE-IVEAFD----GIMVARGDLGVEMPLEAVPLVQKRAIELARIAAKPVIVATQVMDSMIKNPRPTRAEASDCANA 298
Cdd:PRK08187 369 VANLPElIVQAAGrqpfGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA 448
|
330
....*....|
gi 1175903992 299 ilDGADAVML 308
Cdd:PRK08187 449 --ARAECVML 456
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
2-335 |
1.92e-48 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 175.91 E-value: 1.92e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 2 RRAKIVCTI-GPATDSPEQLQALVDAGMDVARINRSHGKAEEHEAVISRVRKASATSGRAVAVLVDLQGPKIRLETFQDG 80
Cdd:PRK14725 139 RPTRIMVTLpTEAADDPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGPIAPG 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 81 PQ------------------------------------------------------------------------------ 82
Cdd:PRK14725 219 PRviklrptrdalgrvltparlwltasespppspppgpvglpvdpewlarlepgdelrftdargkkrkltvtevddegvl 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 83 -----------------------------------ELKVGDTFTITTRDVPGTKEL-------VGTTFKGLPGDCAPGDR 120
Cdd:PRK14725 299 aegsqtaylangtllrlgrhdstrvgglppveqklRLKVGDRLVLTRDDAPGDPAQgdapparISCTLPEAFRAARVGER 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 121 LLIDDGNVAVRVVEVSDTDVVTRVE--VPGVV---SDhKGLNLPGVAVSVPALSEKDKEDLRWAIQMdADFIALSFVRSA 195
Cdd:PRK14725 379 VWFDDGKIGAVVVKVEADEVELRIThaRPGGSklkAG-KGINLPDSHLPLPALTDKDLEDLAFVAKH-ADIVALSFVRSP 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 196 HDIDDVHEIMDEMGKR-IPVIAKIEKPQAVEALEEIV------EAFdGIMVARGDLGVEMPLEAVPLVQKRAIELARIAA 268
Cdd:PRK14725 457 EDVRLLLDALEKLGADdLGVVLKIETRRAFENLPRILleamrhPRF-GVMIARGDLAVEVGFERLAEVQEEILWLCEAAH 535
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1175903992 269 KPVIVATQVMDSMIKNPRPTRAEASDCANAILdgADAVMLSGetsvGAYPIETVRTMAAIIESTEEN 335
Cdd:PRK14725 536 VPVIWATQVLESLAKKGLPSRAEITDAAMALR--AECVMLNK----GPHIVEAVRVLDDILRRMEEH 596
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
355-466 |
1.18e-33 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 122.97 E-value: 1.18e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 355 ICDAAARIAEHMDARYLVTFTQSGTSARLLSRMRRPIPMLAFTPLETTRRRLALSWGIQTYRVPEVQHTDDMVWQLDQVV 434
Cdd:pfam02887 3 IAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVKVA 82
|
90 100 110
....*....|....*....|....*....|..
gi 1175903992 435 QSSRLADIGEQLVIVAGMPPGIPGSSNMLRIH 466
Cdd:pfam02887 83 KEAGLVKKGDLVVITAGVPFGVSGTTNTLKVI 114
|
|
| CitE |
COG2301 |
Citrate lyase beta subunit [Carbohydrate transport and metabolism]; |
174-269 |
7.87e-04 |
|
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
Pssm-ID: 441876 Cd Length: 288 Bit Score: 41.29 E-value: 7.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175903992 174 EDLRWAIQMDADFIALSFVRSAHDIDDVHEIMDEMGK---RIPVIAKIEKPQAVEALEEIVEAFDGIMVAR-------GD 243
Cdd:COG2301 79 DDLAALVGAGLDGIVLPKVESAEDVRALAALLTELEAeggSIPLMALIETARGLLNAAEIAAASPRVEALVfgaedlaAD 158
|
90 100
....*....|....*....|....*.
gi 1175903992 244 LGVEMPLEAVPLVqkRAIELARIAAK 269
Cdd:COG2301 159 LGARRTRDGDELL--YARSRIVLAAR 182
|
|
| HpcH |
COG3836 |
2-keto-3-deoxy-L-rhamnonate aldolase RhmA [Carbohydrate transport and metabolism]; |
214-271 |
9.74e-04 |
|
2-keto-3-deoxy-L-rhamnonate aldolase RhmA [Carbohydrate transport and metabolism];
Pssm-ID: 443047 [Multi-domain] Cd Length: 237 Bit Score: 40.87 E-value: 9.74e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1175903992 214 VIAKIEKPQAVEALEEI--VEAFDGIMVARGDLGVEM--PLEAV-PLVQ---KRAIELARIAAKPV 271
Cdd:COG3836 144 VIVQIETAEAVENLDEIaaVPGVDGVFIGPADLSASLghPGQPDhPEVQaaiERVIAAARAAGKPA 209
|
|
| |
