NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1148876978|ref|WP_077596947|]
View 

MULTISPECIES: ABC transporter permease [Oceanobacillus]

Protein Classification

ABC transporter permease( domain architecture ID 10003093)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-261 5.06e-87

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


:

Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 260.46  E-value: 5.06e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   1 MENKTLRNLYMLPYALWIILFVIAPILLVVYFSFFD------IEGNFSFENYKNFFT-PTYLQMTLNSFWYAFLITLISL 73
Cdd:COG1176     5 LRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  74 LIAYPTAYLLTRT--KHKQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGSR--QLLFTDFSFVFVAVYI 149
Cdd:COG1176    85 LLGYPIAYFLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEplRLLYTEFAVVIGLVYV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 150 FIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAI 229
Cdd:COG1176   165 YLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLI 244

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1148876978 230 EQQFLVTQNWGMGATIAVFLIIIMVGFMALTS 261
Cdd:COG1176   245 YQQFLSALNWPLAAALAVVLLLIVLLVLLLYL 276
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-261 5.06e-87

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 260.46  E-value: 5.06e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   1 MENKTLRNLYMLPYALWIILFVIAPILLVVYFSFFD------IEGNFSFENYKNFFT-PTYLQMTLNSFWYAFLITLISL 73
Cdd:COG1176     5 LRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  74 LIAYPTAYLLTRT--KHKQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGSR--QLLFTDFSFVFVAVYI 149
Cdd:COG1176    85 LLGYPIAYFLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEplRLLYTEFAVVIGLVYV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 150 FIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAI 229
Cdd:COG1176   165 YLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLI 244

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1148876978 230 EQQFLVTQNWGMGATIAVFLIIIMVGFMALTS 261
Cdd:COG1176   245 YQQFLSALNWPLAAALAVVLLLIVLLVLLLYL 276
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 1-253 1.05e-54

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 177.96  E-value: 1.05e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   1 MENKTLRNLYMLPYALWIILFVIAPILLVVYFSFFD------IEGNFSFENYKNFFTPTYLQMTLNSFWYAFLITLISLL 74
Cdd:PRK09497    2 KNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTrddanfVKMVFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  75 IAYPTAYLLTRTKHK--QLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGSR--QLLFTDFSFVFVAVYIF 150
Cdd:PRK09497   82 LGYPFAWFLAKLPHKvrPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTpiRIMFTESAVIIGLVYIL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 151 IPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAIE 230
Cdd:PRK09497  162 LPFMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIK 241

                         250       260
                  ....*....|....*....|...
gi 1148876978 231 QQFLVTQNWGMGATIAVFLIIIM 253
Cdd:PRK09497  242 SQFLNIRDWPFGAATSITLTIVM 264
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 6-265 4.70e-21

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 92.05  E-value: 4.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   6 LRNLYMLPYALWIILFVIAPILLVVYFSFFDIEGNF-SFENYKNFF-TPTYLQMTLNSFWYAFLITLISLLIAYPTAYLL 83
Cdd:TIGR03262   2 IARLLLAGMILALLLFLLLPLLALLTKSVYDSDGDFiGLANFAEYFaTPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  84 TRT--KHKQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANhflEWIGIGSrqlLFTDFSFVFVAVYIFIPFMILPIFNA 161
Cdd:TIGR03262  82 TRSriPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLK---GLLGGFS---IYGFWGIVIGEVFYTFPHALMILVTA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 162 IDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVItLGTAIEQQFLVTQNWGM 241
Cdd:TIGR03262 156 LSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNV-LATDIYKQVIGQQNFPM 234

                         250       260
                  ....*....|....*....|....*
gi 1148876978 242 GATIAVFLII-IMVGFMALTSIRRR 265
Cdd:TIGR03262 235 GAVVGVLLLLpALLAFGIDRAIQRR 259
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-256 4.68e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.59  E-value: 4.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  59 LNSFWYAFLITLISLLIAYPTAYLLTRTKH--KQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGsrqll 136
Cdd:cd06261     2 LNTLLLALIATLLALVLGLLLGIILARKRGklDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPA----- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 137 ftdfsfVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRL 216
Cdd:cd06261    77 ------LILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1148876978 217 IAGNRVITLGTAIEQQFLVTQNWGMGATIAVFLIIIMVGF 256
Cdd:cd06261   151 LGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 135-259 1.24e-04

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 41.90  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 135 LLFTDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLT 214
Cdd:pfam00528  48 LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLL 127

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1148876978 215 RLIAGNRVI-TLGTAIEQQFLVTQNWGMGATIAVFLIIIMVGFMAL 259
Cdd:pfam00528 128 EFLGSWPGLgLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDIL 173
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-261 5.06e-87

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 260.46  E-value: 5.06e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   1 MENKTLRNLYMLPYALWIILFVIAPILLVVYFSFFD------IEGNFSFENYKNFFT-PTYLQMTLNSFWYAFLITLISL 73
Cdd:COG1176     5 LRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  74 LIAYPTAYLLTRT--KHKQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGSR--QLLFTDFSFVFVAVYI 149
Cdd:COG1176    85 LLGYPIAYFLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEplRLLYTEFAVVIGLVYV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 150 FIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAI 229
Cdd:COG1176   165 YLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLI 244

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1148876978 230 EQQFLVTQNWGMGATIAVFLIIIMVGFMALTS 261
Cdd:COG1176   245 YQQFLSALNWPLAAALAVVLLLIVLLVLLLYL 276
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 1-253 1.05e-54

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 177.96  E-value: 1.05e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   1 MENKTLRNLYMLPYALWIILFVIAPILLVVYFSFFD------IEGNFSFENYKNFFTPTYLQMTLNSFWYAFLITLISLL 74
Cdd:PRK09497    2 KNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTrddanfVKMVFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  75 IAYPTAYLLTRTKHK--QLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGSR--QLLFTDFSFVFVAVYIF 150
Cdd:PRK09497   82 LGYPFAWFLAKLPHKvrPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTpiRIMFTESAVIIGLVYIL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 151 IPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAIE 230
Cdd:PRK09497  162 LPFMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIK 241

                         250       260
                  ....*....|....*....|...
gi 1148876978 231 QQFLVTQNWGMGATIAVFLIIIM 253
Cdd:PRK09497  242 SQFLNIRDWPFGAATSITLTIVM 264
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 12-254 2.53e-38

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 136.38  E-value: 2.53e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  12 LPYaLWIILFVIAPILLVVYFSFFDI--------------EGNFSFE-NYKNFFT----PTYLQMTLNSFWYAFLITLIS 72
Cdd:PRK10683   35 LPY-LWLILLFLLPFLIVFKISLAEMaraippytdlmewaDGQLSITlNLGNFLQltddPLYFDAYLQSLQVAAISTLCC 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  73 LLIAYPTAYLLTRTK--HKQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGSRQL--LFTDFSFVFVAVY 148
Cdd:PRK10683  114 LLIGYPLAWAVAHSKpsTRNILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIDQPLtiLHTNLAVYIGIVY 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 149 IFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTA 228
Cdd:PRK10683  194 AYLPFMVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRV 273

                         250       260
                  ....*....|....*....|....*.
gi 1148876978 229 IEQQFLVTQNWGMGATIAVFLIIIMV 254
Cdd:PRK10683  274 LWQEFFNNRDWPVASAVAIIMLLLLI 299
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-266 1.33e-29

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 116.41  E-value: 1.33e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  15 ALWIILFVIAPILLVVYFSFFDIEGNFSfenyKNFFTPTYLQMTLNSFWYAFLITLISLLIAYPTAYLLTRT--KHKQLW 92
Cdd:COG1178    17 ALLLALLVLLPLLALLLRAFTDGLANFW----ALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTdfPGRRLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  93 LLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGSRQLLFTDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYA 172
Cdd:COG1178    93 RWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALFGLEPPDIYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEA 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 173 SKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGnRVITLGTAIEQQFLVTQNWGMGATIAVFLIII 252
Cdd:COG1178   173 ARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLGG-GYTTLTTAIYQAWLGDFDLGAAAALALVLLLL 251

                         250
                  ....*....|....
gi 1148876978 253 MVGFMALTSIRRRG 266
Cdd:COG1178   252 VLLLLLLERRLRRR 265
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
9-259 1.17e-23

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 97.13  E-value: 1.17e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   9 LYMLPYALWIILFVIAPILLVVYFSFFDIEGNFS------FENYKNFFT-PTYLQMTLNSFWYAFLITLISLLIAYPTAY 81
Cdd:COG1175    22 LFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGPppefvgLDNYARLFTdPRFWNALGNTLLFTVVSVPLQLVLGLLLAL 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  82 LLTR-TKHKQLWLLLIIVPSWINLLLKAYAFIGIF-GTHGAANHFLEWIGIGSRQLLFTD----FSFVFVAVYIFIPFMI 155
Cdd:COG1175   102 LLNRkLRGRGFFRTLFFLPWVISPVVVALIWKWLFnPDYGLLNALLGALGLEPINWLGDPslalPAVIIVTVWKGTGFNM 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 156 LPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLF----MLTRLIAGNRVITLGTAIEQ 231
Cdd:COG1175   182 LIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFdlvyVLTGGGPGNSTTTLVLYIYQ 261

                         250       260
                  ....*....|....*....|....*...
gi 1148876978 232 QFLVTQNWGMGATIAVFLIIIMVGFMAL 259
Cdd:COG1175   262 TAFQQFDFGYASAIAVVLFLIILVLTLL 289
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 14-265 1.23e-21

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 90.94  E-value: 1.23e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  14 YALWIILFVIAPILLVVYFSFFDIEGN------FSFENYKNFFT-PTYLQMTLNSFWYAFLITLISLLIAYPTAYLLTRT 86
Cdd:COG1177    12 FLALVLLFLYLPILVLVLYSFNDSWFLtfppegFTLRWYAELFSdPRLLDALLNSLLIALLSTLLATVLGTPAALALARY 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  87 KH--KQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFlewigigsrqllftdFSFVFVAVYIFIPFMILPIFNAIDN 164
Cdd:COG1177    92 RFrgRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGL---------------WGLILAHVVFTLPFVVLVVLARLQG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 165 LNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAIeQQFLVTQNWGMGAT 244
Cdd:COG1177   157 FDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTLPVYI-YSMIRRGISPEINA 235

                         250       260
                  ....*....|....*....|.
gi 1148876978 245 IAVFLIIIMVGFMALTSIRRR 265
Cdd:COG1177   236 LSTLLILLSLLLLLLAERLRR 256
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 6-265 4.70e-21

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 92.05  E-value: 4.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   6 LRNLYMLPYALWIILFVIAPILLVVYFSFFDIEGNF-SFENYKNFF-TPTYLQMTLNSFWYAFLITLISLLIAYPTAYLL 83
Cdd:TIGR03262   2 IARLLLAGMILALLLFLLLPLLALLTKSVYDSDGDFiGLANFAEYFaTPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  84 TRT--KHKQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANhflEWIGIGSrqlLFTDFSFVFVAVYIFIPFMILPIFNA 161
Cdd:TIGR03262  82 TRSriPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLK---GLLGGFS---IYGFWGIVIGEVFYTFPHALMILVTA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 162 IDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVItLGTAIEQQFLVTQNWGM 241
Cdd:TIGR03262 156 LSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNV-LATDIYKQVIGQQNFPM 234

                         250       260
                  ....*....|....*....|....*
gi 1148876978 242 GATIAVFLII-IMVGFMALTSIRRR 265
Cdd:TIGR03262 235 GAVVGVLLLLpALLAFGIDRAIQRR 259
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-259 1.01e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 82.13  E-value: 1.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   6 LRNLYMLPYALWIILFVIAPILLVVYFSFFD-IEGNFSFENYKN-FFTPTYLQMTLNSFWYAFLITLISLLIAYPTAYLL 83
Cdd:COG1178   286 WRWLALALCLLLVLLGLLLPLLALLLWSLTKaLDDNLTLDNYRFvLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLV 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  84 TRTKHKQLWLLLIIvpswinlllkAYAFIGIFGTHGAANHFLEWIGIGSRQLLFTDFSFVFVAVYIFIPFMILPIFNAID 163
Cdd:COG1178   366 RRRRGRLARLLDRL----------AMLPYAVPGIVLGLGLLLLFNRPLPLLLYGTLAILVLAYVVRFLPFALRSLEAALA 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 164 NLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAIEQQfLVTQNWGMGA 243
Cdd:COG1178   436 QIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIYQL-ASSGRYGEAA 514

                         250
                  ....*....|....*.
gi 1148876978 244 TIAVFLIIIMVGFMAL 259
Cdd:COG1178   515 ALALLLVLVSLLPVLL 530
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 50-266 2.08e-17

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 78.55  E-value: 2.08e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  50 FTPTYLQMTLNSFWYAFLITLISLLIAYPTAYLLTRTKHKQLWLLLIIV-------PSWINLLLkayafIGIFGTHGAAN 122
Cdd:COG4149     1 LSPEDWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVtlplvlpPTVLGFYL-----LLLFGRNGPLG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 123 HFLE-WIGIgsrQLLFTDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQ 201
Cdd:COG4149    76 QLLEeLFGI---SLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAV 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1148876978 202 VVFIPALSLFMLTRLIAGN---RVITLGTAIeqqFLVTQNWGMGATIAVFLIIIMVGFMALTSIRRRG 266
Cdd:COG4149   153 LAFARALGEFGATLMFAGNipgKTQTLPLAI---YDAVEAGDYAAAHALSLILLAISFVVLLLLNLLN 217
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 15-265 1.04e-16

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 77.48  E-value: 1.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  15 ALWIILFVIAPILLVVYFSFfdiegNFSFENY-KNFFTPTYLQMTLNSFWYAFLITLISLLIAYPTAYLLTRTKHKQLWL 93
Cdd:COG0555    17 LLYLSLIVLLPLAALVLKAA-----GLGWAEFwAVLTSPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  94 L--LIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIgsrQLLFTDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLY 171
Cdd:COG0555    92 VdaLVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGI---KVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 172 ASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGN---RVITLGTAIEQQfLVTQNWGMGATIAVF 248
Cdd:COG0555   169 AAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEFGAVIFIAGNlpmKTEILPLLIYLK-LEEGDYAGATAIALV 247

                         250
                  ....*....|....*..
gi 1148876978 249 LIIIMVGFMALTSIRRR 265
Cdd:COG0555   248 LLLISFLLLLLINLLQR 264
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 9-259 9.89e-15

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 72.34  E-value: 9.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   9 LYMLPYALWIILFVIAPILLVVYFSFFDiEGNFSFENYKNFFT-PTYLQMTLNSFWYAFLIT--------LISLLIAY-- 77
Cdd:PRK15050   26 LWLLLPLLVLAPLVVYPLVRVVLQSLTG-EHGLGLATYRAVLGsPDFRGALLTTLQIAFASTagclvlgvLLALVLAFvp 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  78 -PTAYLLTRtkhkqLWLLLIIVPSWinllLKAYAFIGIFGTHGAANHFL-EWIGIGSRQL--LFTDFSFVFVAVYIFIPF 153
Cdd:PRK15050  105 fPGASLVGR-----FIDTFVAFPSF----LITLAFTFLYGSAGSVNIALqRLFGLEAPPLdfLYSPGGVILAEITFYTPF 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 154 MILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGNRVITLGTAIEQQF 233
Cdd:PRK15050  176 VVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAKDVVTLPVLIYSKA 255

                         250       260
                  ....*....|....*....|....*.
gi 1148876978 234 LVTQNWGMGATIAVFLIIIMVGFMAL 259
Cdd:PRK15050  256 IVDFDYPTACAIAVVNLALSLGLYAL 281
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-256 4.68e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.59  E-value: 4.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  59 LNSFWYAFLITLISLLIAYPTAYLLTRTKH--KQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIGsrqll 136
Cdd:cd06261     2 LNTLLLALIATLLALVLGLLLGIILARKRGklDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPA----- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 137 ftdfsfVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRL 216
Cdd:cd06261    77 ------LILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1148876978 217 IAGNRVITLGTAIEQQFLVTQNWGMGATIAVFLIIIMVGF 256
Cdd:cd06261   151 LGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
cysT CHL00187
sulfate transport protein; Provisional
 61-220 2.04e-08

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 53.48  E-value: 2.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  61 SFWYAFLITLISLLIAYPTAYLLTRT--KHKQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIgsrQLLFT 138
Cdd:CHL00187   60 TLSMALIAALINGFFGLLIAWVLVRYnfPGKRLLDAAVDLPFALPTSVAGLTLATVYGDNGWIGHLLSHLGI---QIVFT 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 139 DFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIA 218
Cdd:CHL00187  137 KLGVLLAMIFVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEYGSIVIIS 216


                  ..
gi 1148876978 219 GN 220
Cdd:CHL00187  217 SN 218
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-191 4.35e-08

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 52.79  E-value: 4.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  18 IILFVIAPILLVVYFSFFD-----------IEGNFSFENYKNFFT-PTYLQMTLNSFWYAFLITLISLLIAYPTAYLLTR 85
Cdd:COG0395    24 LALLFLFPLYWMVVTSFKPpaeifsgppslLPSEFTLENYRAAFTdGPFGRYLLNSLIVAVVSTVLSLLLSSLAAYALAR 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  86 --TKHKQLWLLLIIVPSWINL------LLKAYAFIGIFGTHgaanhflewigigsrqllftdFSFVFVAVYIFIPFMILP 157
Cdd:COG0395   104 frFRGRKLLFLLILATLMIPGqvllipLYLLFRQLGLLNTY---------------------WGLILPYLAFGLPFGIFL 162

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1148876978 158 IFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPL 191
Cdd:COG0395   163 LRQFFRSIPRELEEAARIDGASEFRIFWRIVLPL 196
permease_CysT TIGR02139
sulfate ABC transporter, permease protein CysT; This model represents CysT, one of two ...
 61-220 3.39e-07

sulfate ABC transporter, permease protein CysT; This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions]


Pssm-ID: 131194  Cd Length: 265  Bit Score: 50.02  E-value: 3.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  61 SFWYAFLITLISLLIAYPTAYLLTRTKH--KQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGIgsrQLLFT 138
Cdd:TIGR02139  55 SFGTALIAALINAVFGTLLAWVLVRYRFpgKRIVDALVDLPFALPTAVAGIALATLYSPNGWIGSFLAPLGI---KIAFT 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 139 DFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIA 218
Cdd:TIGR02139 132 PLGIVIALVFVSLPFVVRTVQPVLEEIEKELEEAAASLGASRWQTFWRVILPALLPALLTGFALAFARAVGEYGSVIFIA 211


                  ..
gi 1148876978 219 GN 220
Cdd:TIGR02139 212 GN 213
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 3-199 2.21e-06

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 47.67  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978   3 NKTLRNLYMlpyalWII-LFVIAPILLVVYFSF----FDIE-GNFSFENYKNFFT-PTYLQMTLNSFWYAFLITLISLLI 75
Cdd:PRK09500    2 GRLLRGGFM-----TLVyAYLYIPIIILIVNSFnssrFGINwKGFTTKWYELLFNnDSLLQAAQHSLTMAVFSATFATLI 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  76 AYPTAYLLTRTKHK-----QLWLLLIIVPSWINLLLKAYAFIGIFGthgaanhflewIGIGSRQLLFTDFSFVfvavyif 150
Cdd:PRK09500   77 GSLTAVALYRYRFRgkkfvSGMLFVVMMSPDIVMAISLLVLFMLLG-----------IQLGFWSLLFAHITFC------- 138

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1148876978 151 IPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSG 199
Cdd:PRK09500  139 LPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAG 187
modB PRK09421
molybdate ABC transporter permease subunit;
50-211 2.83e-06

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 47.22  E-value: 2.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  50 FTPTYLQMTLNSFWYAFLITLISLLIAYPTAYLLTRTKH--KQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANHFL-E 126
Cdd:PRK09421    3 LSDPEWQAVLLSLKVSSVAVLFSLPFGILVAWLLARCRFpgKSLLDSLLHLPLVLPPVVTGYLLLISMGRRGFIGQWLyE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 127 WIGIgsrqllftDFSF-----VFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQ 201
Cdd:PRK09421   83 WFGI--------SFAFswrgaALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTV 154

                         170
                  ....*....|
gi 1148876978 202 VVFIPALSLF 211
Cdd:PRK09421  155 LAFARSLGEF 164
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 135-259 1.24e-04

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 41.90  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 135 LLFTDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLT 214
Cdd:pfam00528  48 LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLL 127

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1148876978 215 RLIAGNRVI-TLGTAIEQQFLVTQNWGMGATIAVFLIIIMVGFMAL 259
Cdd:pfam00528 128 EFLGSWPGLgLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDIL 173
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 127-259 1.84e-04

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 41.67  E-value: 1.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 127 WIGIGsrqllftDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIP 206
Cdd:COG0600   120 WFGIG-------EASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGL 192

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1148876978 207 ALSLFMLTRLIAGNRviTLGtaieqqFLVTQNWGMGATIAVFLIIIMVGFMAL 259
Cdd:COG0600   193 AWIGLVVAELLGASS--GLG------YLILDARQLLDTDLVFAAILVIGLLGL 237
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
59-190 2.42e-04

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 41.66  E-value: 2.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  59 LNSFWYAFLITLIS----LLIAYPTAYLLTRTKH--KQLWLLLIIVPSWINLLLKAYAFIGIFGTHGAANhflEWIGIGS 132
Cdd:PRK11602   63 LHAIWLTVLIALIAvpvnLVFGILLAWLVTRFNFpgRQLLLTLLDIPFAVSPVVAGLVYLLFYGSNGPLG---GWLDEHN 139

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1148876978 133 RQLLFTDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFP 190
Cdd:PRK11602  140 LQLMFSWPGMVLVTIFVTCPFVVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLP 197
thiP PRK09433
thiamine transporter membrane protein; Reviewed
 16-130 4.30e-04

thiamine transporter membrane protein; Reviewed


Pssm-ID: 181853 [Multi-domain]  Cd Length: 525  Bit Score: 41.36  E-value: 4.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  16 LWIILFVIAPILLVVYFSFFDIEGNFSFENYKNFFTPTYL-QMTLNSFWYAFLITLISLLIAYPTAYLLTRT--KHKQLW 92
Cdd:PRK09433    3 LIPGVLAAALLVALALLALLALWLHAPGGDWDAVWQDSYLwHVLRFSFWQAFLSALLSVLPAIPLARALYRRrfPGRGLL 82

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1148876978  93 LLLIIVPSWINLLLKAYAFIGIFGTHGAANHFLEWIGI 130
Cdd:PRK09433   83 LRLCAMTLVLPVLVAVFGLLSVYGRSGWLAQLLQALGL 120
thiP TIGR01253
thiamine ABC transporter, permease protein; The model describes thiamine ABC transporter, ...
 22-261 2.11e-03

thiamine ABC transporter, permease protein; The model describes thiamine ABC transporter, permease protein in bacteria. The protein belongs to the larger ABC transport system. It consists of atleast three components: the inner mebrane permease; thiamine binding protein; an ATP-binding subunit. It has been experimentally demonstrated that the mutants in the various steps in the de novo synthesis of the thiamine and the biologically active form, namely thiamine pyrophosphate can be exogenously supplemented with thiamine, thiamine monophosphate (TMP) or thiamine pyrophosphate (TPP). [Transport and binding proteins, Other]


Pssm-ID: 130320 [Multi-domain]  Cd Length: 519  Bit Score: 39.13  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978  22 VIAPILLVVYFSFFDIEGNFSFENYKNFFTPTYLQ-MTLNSFWYAFLITLISLLIAYPTAYLLTRTKH-KQLWLLLIIVP 99
Cdd:TIGR01253  12 AISFIIAFAGAAFLAIFALAGEDDWRAVFQDDYLQhLILFSFGQAFLSALLSIFFAIFLARALFRKPFlGKKALLKLCAL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 100 SWI-NLLLKAYAFIGIFGTHGAANHFLEWIGIGSRQLLFTDFSFVFVAVYIFIPFMILPIFNAIDNLNSSLLYASKDLGA 178
Cdd:TIGR01253  92 TFIlPALVAIFGIIGIYGRQGWLATLANLFGLEWQFHIYGLQGILIAHLFFNIPLAAQLFLQALENIPGEQRQLAAQLGL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 179 SKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLF-MLTRLIAGNRVITLGTAIEQQFLVTQNWGMGATIAVFLIIIMVGFM 257
Cdd:TIGR01253 172 QGWHFFKFVEWPVFRQQCLPTAALIFMLCFASFaTVLSLGGGPQATTIELAIYQAILFDFDLAKAALFALLQFVCCLGLF 251


                  ....
gi 1148876978 258 ALTS 261
Cdd:TIGR01253 252 LLSQ 255
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
151-220 2.43e-03

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 38.58  E-value: 2.43e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148876978 151 IPFMILPIFNAIDNLNSSLLYASKDLGASKWTTFRRVIFPLTIDGVKSGCQVVFIPALSLFMLTRLIAGN 220
Cdd:PRK10971  152 IPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIAGN 221
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH