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Conserved domains on  [gi|1143084548|ref|WP_077075989|]
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antitoxin VapB family protein [Cuniculiplasma divulgatum]

Protein Classification

antitoxin VapB family protein( domain architecture ID 10004453)

antitoxin VapB family protein is a putative type II toxin-antitoxin system VapB family antitoxin and may bind to and neutralize the effect of its cognate VapC toxin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VapB3 COG1753
Predicted antitoxin, CopG family [Defense mechanisms];
2-71 2.16e-12

Predicted antitoxin, CopG family [Defense mechanisms];


:

Pssm-ID: 441359  Cd Length: 76  Bit Score: 56.11  E-value: 2.16e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143084548  2 STKNIALRDDVYKKLKEVKGPNESFSDAIEELLKRKGSLLPLWSSLSESEAIDLIETDLKAIRNGAKIRA 71
Cdd:COG1753    1 MTKTISISDEVYERLKRIKREDESFSDVIERLLKERKEDLLEGFGTLSDEEADELEEAVKESREEFDERL 70
 
Name Accession Description Interval E-value
VapB3 COG1753
Predicted antitoxin, CopG family [Defense mechanisms];
2-71 2.16e-12

Predicted antitoxin, CopG family [Defense mechanisms];


Pssm-ID: 441359  Cd Length: 76  Bit Score: 56.11  E-value: 2.16e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143084548  2 STKNIALRDDVYKKLKEVKGPNESFSDAIEELLKRKGSLLPLWSSLSESEAIDLIETDLKAIRNGAKIRA 71
Cdd:COG1753    1 MTKTISISDEVYERLKRIKREDESFSDVIERLLKERKEDLLEGFGTLSDEEADELEEAVKESREEFDERL 70
VAPB_antitox pfam02697
Putative antitoxin; Proteins in this family are possibly the antitoxin component of a ...
 4-68 2.84e-09

Putative antitoxin; Proteins in this family are possibly the antitoxin component of a VAPBC-like toxin-antitoxin (TA) module, which is widespread in the in both archaea and bacteria.


Pssm-ID: 397010  Cd Length: 69  Bit Score: 47.67  E-value: 2.84e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1143084548  4 KNIALRDDVYKKLKEVKGPNESFSDAIEELLKRKGSLLPLWSSLS----ESEAIDLIETDLKAIRNGAK 68
Cdd:pfam02697  1 KTISISDEVYEKLKKRKGEGESFSDVIERLLEKKKKGNLDDLLELfgilSDEEADEIEKASKEMRKEFR 69
PRK13696 PRK13696
hypothetical protein; Provisional
 1-37 2.16e-05

hypothetical protein; Provisional


Pssm-ID: 237476  Cd Length: 62  Bit Score: 37.70  E-value: 2.16e-05
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 1143084548  1 MSTKNIALRDDVYKKLKEVKGpNESFSDAIEELLKRK 37
Cdd:PRK13696   1 MMMKTITISDDVYEKLLEIKG-DKSFSEVIRELIEKK 36
 
Name Accession Description Interval E-value
VapB3 COG1753
Predicted antitoxin, CopG family [Defense mechanisms];
2-71 2.16e-12

Predicted antitoxin, CopG family [Defense mechanisms];


Pssm-ID: 441359  Cd Length: 76  Bit Score: 56.11  E-value: 2.16e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143084548  2 STKNIALRDDVYKKLKEVKGPNESFSDAIEELLKRKGSLLPLWSSLSESEAIDLIETDLKAIRNGAKIRA 71
Cdd:COG1753    1 MTKTISISDEVYERLKRIKREDESFSDVIERLLKERKEDLLEGFGTLSDEEADELEEAVKESREEFDERL 70
VAPB_antitox pfam02697
Putative antitoxin; Proteins in this family are possibly the antitoxin component of a ...
 4-68 2.84e-09

Putative antitoxin; Proteins in this family are possibly the antitoxin component of a VAPBC-like toxin-antitoxin (TA) module, which is widespread in the in both archaea and bacteria.


Pssm-ID: 397010  Cd Length: 69  Bit Score: 47.67  E-value: 2.84e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1143084548  4 KNIALRDDVYKKLKEVKGPNESFSDAIEELLKRKGSLLPLWSSLS----ESEAIDLIETDLKAIRNGAK 68
Cdd:pfam02697  1 KTISISDEVYEKLKKRKGEGESFSDVIERLLEKKKKGNLDDLLELfgilSDEEADEIEKASKEMRKEFR 69
PRK13696 PRK13696
hypothetical protein; Provisional
 1-37 2.16e-05

hypothetical protein; Provisional


Pssm-ID: 237476  Cd Length: 62  Bit Score: 37.70  E-value: 2.16e-05
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 1143084548  1 MSTKNIALRDDVYKKLKEVKGpNESFSDAIEELLKRK 37
Cdd:PRK13696   1 MMMKTITISDDVYEKLLEIKG-DKSFSEVIRELIEKK 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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