|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-426 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 942.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 1 MSEIREVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEIL 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 81 GFDALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 161 DIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGYNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 241 LDVAATELYKDGFYVLEGEGVKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVE 320
Cdd:COG0148 241 LDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 321 RLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAK 400
Cdd:COG0148 321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400
|
410 420
....*....|....*....|....*.
gi 1132175068 401 YNQLLRIEEELDYTAIYKGLKAFYNI 426
Cdd:COG0148 401 YNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-427 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 904.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 1 MSEIREVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEIL 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 81 GFDALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 161 DIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGYNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 241 LDVAATELYKDGFYVLEGEGvkKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVE 320
Cdd:PRK00077 241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 321 RLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAK 400
Cdd:PRK00077 319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398
|
410 420
....*....|....*....|....*..
gi 1132175068 401 YNQLLRIEEELDYTAIYKGLKAFYNIK 427
Cdd:PRK00077 399 YNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-410 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 782.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 6 EVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEILGFDAL 85
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 86 DQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNVDIQEF 165
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 166 MIMPLGADSFGEALRMGAEVFHNLKKVLKGKG--YNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIALDV 243
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 244 AATELYKDGFYVLEG-EGVKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVERL 322
Cdd:cd03313 241 AASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 323 QKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAKYN 402
Cdd:cd03313 321 KKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYN 400
|
....*...
gi 1132175068 403 QLLRIEEE 410
Cdd:cd03313 401 QLLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-426 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 781.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 4 IREVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEILGFD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 84 ALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNVDIQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 164 EFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGYNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIALDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 244 AATELY--KDGFYVLEGEGVKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVER 321
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 322 LQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAKY 401
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 1132175068 402 NQLLRIEEELDYTAIYKGLKAFYNI 426
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
141-426 |
2.01e-157 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 446.16 E-value: 2.01e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 141 VLPAPMMNILNGGKHADNNVDIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGY--NTAVGDEGGFAPNLKSNEEA 218
Cdd:pfam00113 3 VLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGqsATNVGDEGGFAPNLQSNKEA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 219 IEVIVEAIEKAGFTPgkDIYIALDVAATELY--KDGFYVLEGEG------VKKTASEMVEYYEKLSAKYPIISIEDGMSE 290
Cdd:pfam00113 83 LDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 291 EDWEGWKLLTERLGKKIQLVGDDLFVTNVERLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGET 370
Cdd:pfam00113 161 DDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGET 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1132175068 371 EDTTLADLAVAVNAGMIKTGAPSRTDRVAKYNQLLRIEEELDYTAIYKGLKAFYNI 426
Cdd:pfam00113 241 EDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-426 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 942.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 1 MSEIREVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEIL 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 81 GFDALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 161 DIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGYNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 241 LDVAATELYKDGFYVLEGEGVKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVE 320
Cdd:COG0148 241 LDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 321 RLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAK 400
Cdd:COG0148 321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400
|
410 420
....*....|....*....|....*.
gi 1132175068 401 YNQLLRIEEELDYTAIYKGLKAFYNI 426
Cdd:COG0148 401 YNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-427 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 904.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 1 MSEIREVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEIL 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 81 GFDALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 161 DIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGYNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 241 LDVAATELYKDGFYVLEGEGvkKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVE 320
Cdd:PRK00077 241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 321 RLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAK 400
Cdd:PRK00077 319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398
|
410 420
....*....|....*....|....*..
gi 1132175068 401 YNQLLRIEEELDYTAIYKGLKAFYNIK 427
Cdd:PRK00077 399 YNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-410 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 782.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 6 EVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEILGFDAL 85
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 86 DQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNVDIQEF 165
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 166 MIMPLGADSFGEALRMGAEVFHNLKKVLKGKG--YNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIALDV 243
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 244 AATELYKDGFYVLEG-EGVKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVERL 322
Cdd:cd03313 241 AASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 323 QKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAKYN 402
Cdd:cd03313 321 KKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYN 400
|
....*...
gi 1132175068 403 QLLRIEEE 410
Cdd:cd03313 401 QLLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-426 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 781.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 4 IREVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEILGFD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 84 ALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADNNVDIQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 164 EFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGYNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTPGKDIYIALDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 244 AATELY--KDGFYVLEGEGVKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERLGKKIQLVGDDLFVTNVER 321
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 322 LQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAKY 401
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 1132175068 402 NQLLRIEEELDYTAIYKGLKAFYNI 426
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-419 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 592.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 1 MSEIREVIAREILDSRGNPTVEVDVILEDGSWgRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEIL 80
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 81 GFDALDQVGIDEYLIE-LDGTPN-----KGKLGANAILGVSMAVAKAAANYLGLPLYRYLGG-----TNARVLPAPMMNI 149
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQlagkpTDKFVLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 150 LNGGKHADNNVDIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKgYN---TAVGDEGGFAPNLKSNEEAIEVIVEAI 226
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKK-YGldaTNVGDEGGFAPNIKDPEEALDLLVEAI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 227 EKAGFTpGKdIYIALDVAATELYKD-------GFYVLEGEG-VKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKL 298
Cdd:PTZ00081 239 KKAGYE-GK-VKICMDVAASEFYDKekkvydlDFKNPNNDKsNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAK 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 299 LTERLGKKIQLVGDDLFVTNVERLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADL 378
Cdd:PTZ00081 317 LTAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADL 396
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1132175068 379 AVAVNAGMIKTGAPSRTDRVAKYNQLLRIEEELDYTAIYKG 419
Cdd:PTZ00081 397 VVGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
|
|
| PLN00191 |
PLN00191 |
enolase |
1-419 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 561.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 1 MSEIREVIAREILDSRGNPTVEVDVILEDGsWGRAAVPSGASTGAFEAVELRDNDpKRYLGKGVTQAVENVNSIIGPEIL 80
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKG-MFRAAVPSGASTGIYEALELRDGD-KDYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 81 GFDALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRY---LGGTNARVLPAPMMNILNGGKHAD 157
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 158 NNVDIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGK--GYNTAVGDEGGFAPNLKSNEEAIEVIVEAIEKAGFTpGK 235
Cdd:PLN00191 183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT-GK 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 236 dIYIALDVAATELY-KDGFYVLEGE------GVKKTASEMVEYYEKLSAKYPIISIEDGMSEEDWEGWKLLTERlgKKIQ 308
Cdd:PLN00191 262 -IKIGMDVAASEFYtKDKKYDLDFKeenndgSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--EDVQ 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 309 LVGDDLFVTNVERLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVNAGMIK 388
Cdd:PLN00191 339 IVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIK 418
|
410 420 430
....*....|....*....|....*....|.
gi 1132175068 389 TGAPSRTDRVAKYNQLLRIEEELDYTAIYKG 419
Cdd:PLN00191 419 TGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
141-426 |
2.01e-157 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 446.16 E-value: 2.01e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 141 VLPAPMMNILNGGKHADNNVDIQEFMIMPLGADSFGEALRMGAEVFHNLKKVLKGKGY--NTAVGDEGGFAPNLKSNEEA 218
Cdd:pfam00113 3 VLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGqsATNVGDEGGFAPNLQSNKEA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 219 IEVIVEAIEKAGFTPgkDIYIALDVAATELY--KDGFYVLEGEG------VKKTASEMVEYYEKLSAKYPIISIEDGMSE 290
Cdd:pfam00113 83 LDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 291 EDWEGWKLLTERLGKKIQLVGDDLFVTNVERLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGET 370
Cdd:pfam00113 161 DDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGET 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1132175068 371 EDTTLADLAVAVNAGMIKTGAPSRTDRVAKYNQLLRIEEELDYTAIYKGLKAFYNI 426
Cdd:pfam00113 241 EDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
4-134 |
2.42e-92 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 274.25 E-value: 2.42e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 4 IREVIAREILDSRGNPTVEVDVILEDGSWGRAAVPSGASTGAFEAVELRDNDPKRYLGKGVTQAVENVNSIIGPEILGFD 83
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1132175068 84 ALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYL 134
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
1-411 |
4.66e-28 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 113.36 E-value: 4.66e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 1 MSEIREVIAREILDSRGNPTVEVDVILEDGsWGRAAVPSgastgafeavelrDNDPKRYLGKGvTQAVENVNSIIGPEIL 80
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 81 GFDALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGgkhadnnv 160
Cdd:PRK08350 66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAED-------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 161 DIQEFMIMplgadsfgeaLRMGAEVFHNLKKVLKGKGYntavgdeggfapnlkSNEEAIEVIVEAIEKAGFTPGkdiyia 240
Cdd:PRK08350 138 ENFEYYVL----------VRDLMEITDVVDAVNKILEN---------------SKEVSLEGLSKASEKAGDELG------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 241 LDVAAtelykdgfyvlegeGVKKTASEMVEYYEKLSAKYPIISIEDGMSEEdwegwkLLTERLG--KKIQLVGDDLFvtn 318
Cdd:PRK08350 187 LEVAL--------------GIAQKREMETEKVLNLVEDNNIAYIKPIGDEE------LFLELIAgtHGVFIDGEYLF--- 243
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 319 veRLQKGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSGETEDTTLADLAVAVN--AGMIktgapsRTD 396
Cdd:PRK08350 244 --RTRNILDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRcpAMLI------HKD 315
|
410
....*....|....*
gi 1132175068 397 RVAKYNQLLRIEEEL 411
Cdd:PRK08350 316 SVEKINELNRIAEDL 330
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
214-389 |
3.41e-16 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 77.37 E-value: 3.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 214 SNEEAIEVIVEAIekagftpGKDIYIALDVAATElykdgfyvlegegvkkTASEMVEYYEKLsAKYPIISIEDGMSEEDW 293
Cdd:cd00308 79 GSIERVRAVREAF-------GPDARLAVDANGAW----------------TPKEAIRLIRAL-EKYGLAWIEEPCAPDDL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 294 EGWKLLTERLGkkIQLVGDDLFVTNVERLQkGISLGVANSILIKLNQIGTITETLNAIELARQNGYTAVISHRSG-ETED 372
Cdd:cd00308 135 EGYAALRRRTG--IPIAADESVTTVDDALE-ALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLEsSIGT 211
|
170
....*....|....*...
gi 1132175068 373 TTLADLAVAV-NAGMIKT 389
Cdd:cd00308 212 AAALHLAAALpNDRAIET 229
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
2-411 |
1.04e-11 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 66.44 E-value: 1.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 2 SEIREVIAREILDSRGNPTVEVDVILEDGswgrAAVPSGASTGAfeAVELRDNDPKRYL--GKGVTQAVENvnSIIgPEI 79
Cdd:PTZ00378 49 DEIRALVHNEVLSPAGETVLRFTLELLNG----MEVSSGALLSP--SHGERDGEADATLdpAEYTTEALQN--SYF-PRL 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 80 LGFDALDQVGIDEYLIELDGTPNKGKLGANAILGVSMAVAKAAANYLGLPLYRYLGG-----TNARVLPAPMMNI--LNG 152
Cdd:PTZ00378 120 LQLGARDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLRAlfgslTSVETFSMPQLCItfFGP 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 153 GKHADNNVDIQEFMI---MPLGADSfGEALRMGAEVFHNLKKVlkgkgYNTAVGDEGGFAPNLKSN-EEAIEVIVEAIEK 228
Cdd:PTZ00378 200 GNPSTARLALKSVLFspvMPSGTVL-RERMQKIFAAFHHFCQS-----HNSSVRSDGSLHWDGFANlTDAVKLATEALRA 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 229 AGFTPGKDIYIALDVAA--TELY-------------KDG---FYVLEGEGVKKTASEMVEYY-EKLSAKYPIIS-IEDGM 288
Cdd:PTZ00378 274 VQLTPGTDVCLGLRMAAstTRVPatavadggawkeaKDDcevLYSLFPGEPDVTGDQLSEYVrEQLQAVPDIVVyVEDTH 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 289 SEEDWEGWKLLTERLGKKIQLVGDDLFV-TNVERLQKGISLGVANSILIKLNQIGTITETLNAIELARQN-GYTAVISHR 366
Cdd:PTZ00378 354 CDEDTFGLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEDeGRAVTVLVQ 433
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1132175068 367 SGETEDTTLADLAVAVNAGMIKTGAPSRTDRVAKYNQLLRIEEEL 411
Cdd:PTZ00378 434 TLAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
21-358 |
4.60e-07 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 51.36 E-value: 4.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 21 VEVDVILEDGSWGRAAVPSGASTGAFEA--VELRDND---------PKRYLGKGVTQAVENVnsiIGPEILGFDALDQVG 89
Cdd:COG4948 4 TDIEVYPVRLPLKRPFTISRGTRTERDVvlVRVETDDgitgwgeavPGGTGAEAVAAALEEA---LAPLLIGRDPLDIEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 90 IDEYLIELDGTPNkgklgaNAILGVSMAVAKAAANYLGLPLYRYLGGTNARVLPApmmnilnggkhaDNNVDIQEFMIMp 169
Cdd:COG4948 81 LWQRLYRALPGNP------AAKAAVDMALWDLLGKALGVPVYQLLGGKVRDRVPV------------YATLGIDTPEEM- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 170 lgADSFGEALRMGaevFHNLKkvLKGkgyntavgdeGGFAPnlksnEEAIEvIVEAIEKAGftpGKDIYIALDvaATELY 249
Cdd:COG4948 142 --AEEAREAVARG---FRALK--LKV----------GGPDP-----EEDVE-RVRAVREAV---GPDARLRVD--ANGAW 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 250 kdgfyvlegegvkkTASEMVEYYEKLsAKYPIISIEDGMSEEDWEGWKLLTERLGkkIQLVGDDLfVTNVERLQKGISLG 329
Cdd:COG4948 194 --------------TLEEAIRLLRAL-EDLGLEWIEQPLPAEDLEGLAELRRATP--VPIAADES-LTSRADFRRLIEAG 255
|
330 340
....*....|....*....|....*....
gi 1132175068 330 VANSILIKLNQIGTITETLNAIELARQNG 358
Cdd:COG4948 256 AVDIVNIKLSKVGGLTEALRIAALAEAHG 284
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
284-358 |
5.13e-04 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 41.84 E-value: 5.13e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1132175068 284 IEDGMSEEDWEGWKLLTERLGKKIQLvgdDLFVTNVERLQKGISLGVANSILIKLNQIGTITETLNAIELARQNG 358
Cdd:cd03317 208 IEQPLAADDLIDHAELQKLLKTPICL---DESIQSAEDARKAIELGACKIINIKPGRVGGLTEALKIHDLCQEHG 279
|
|
| mandelate_racemase |
cd03321 |
Mandelate racemase (MR) catalyzes the Mg2+-dependent 1,1-proton transfer reaction that ... |
110-358 |
1.14e-03 |
|
Mandelate racemase (MR) catalyzes the Mg2+-dependent 1,1-proton transfer reaction that interconverts the enantiomers of mandelic acid. MR is the first enzyme in the bacterial pathway that converts mandelic acid to benzoic acid and allows this pathway to utilize either enantiomer of mandelate. MR belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239437 [Multi-domain] Cd Length: 355 Bit Score: 40.93 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 110 AILGVSMAVAKAAANYLGLPLYRYLGGtNARVLPAPMMNILNGGKHADNnvdiqefmimplgadsfgEALRMGAEVFHNL 189
Cdd:cd03321 100 AAAGIDMAAWDALAKVHGLPLAKLLGG-NPRPVQAYDSHGLDGAKLATE------------------RAVTAAEEGFHAV 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 190 KKVLkgkGYntavgdeggfaPNLKSNEEAIEVIVEAIEKaGFTPGKDIYIALDVAATELYKDGfyvLEGEGVKktasemv 269
Cdd:cd03321 161 KTKI---GY-----------PTADEDLAVVRSIRQAVGD-GVGLMVDYNQSLTVPEAIERGQA---LDQEGLT------- 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 270 eyyeklsakypiiSIEDGMSEEDWEGWKLLTERLGKKIQlVGDDLFvtNVERLQKGISLGVANSILIKLNQIGTITETLN 349
Cdd:cd03321 216 -------------WIEEPTLQHDYEGHARIASALRTPVQ-MGENWL--GPEEMFKALSAGACDLVMPDLMKIGGVTGWLR 279
|
....*....
gi 1132175068 350 AIELARQNG 358
Cdd:cd03321 280 ASALAEQAG 288
|
|
| MLE_like |
cd03315 |
Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this ... |
113-364 |
3.75e-03 |
|
Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and residues that can function as general acid/base catalysts, a Lys-X-Lys motif and another conserved lysine. Despite these conserved residues, the members of the MLE subgroup, like muconate lactonizing enzyme, o-succinylbenzoate synthase (OSBS) and N-acylamino acid racemase (NAAAR), catalyze different reactions.
Pssm-ID: 239431 [Multi-domain] Cd Length: 265 Bit Score: 38.86 E-value: 3.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 113 GVSMAVAKAAANYLGLPLYRYLGGTNARVLPAPMMNILNGGKHADnnvdiqefmimplgadsfgEALRMGAEVFHNLK-K 191
Cdd:cd03315 47 AVDMALWDLWGKRLGVPVYLLLGGYRDRVRVAHMLGLGEPAEVAE-------------------EARRALEAGFRTFKlK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 192 VLKGKGYNTAVgdeggfapnlksneeaIEVIVEAIekagftpGKDIYIALDvaATELYkdgfyvlegegvkkTASEMVEY 271
Cdd:cd03315 108 VGRDPARDVAV----------------VAALREAV-------GDDAELRVD--ANRGW--------------TPKQAIRA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1132175068 272 YEKLSAkYPIISIEDGMSEEDWEGWKLLTERLGkkIQLVGDDLfVTNVERLQKGISLGVANSILIKLNQIGTITETLNAI 351
Cdd:cd03315 149 LRALED-LGLDYVEQPLPADDLEGRAALARATD--TPIMADES-AFTPHDAFRELALGAADAVNIKTAKTGGLTKAQRVL 224
|
250
....*....|...
gi 1132175068 352 ELARQNGYTAVIS 364
Cdd:cd03315 225 AVAEALGLPVMVG 237
|
|
| |
