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Conserved domains on  [gi|1124707143|ref|WP_074985127|]
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tetratricopeptide repeat protein [Paraburkholderia tropica]

Protein Classification

tetratricopeptide repeat-containing glycosyltransferase family protein( domain architecture ID 1004896)

tetratricopeptide repeat-containing glycosyltransferase family protein may catalyze the transfer of saccharide moieties from a donor to an acceptor to form glycosidic bonds

CATH:  1.25.40.10
Gene Ontology:  GO:0016757|GO:0005515
PubMed:  12691742|16037492|21153002|10517866|30708253
SCOP:  3001586|4001344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-275 4.14e-32

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 131.27  E-value: 4.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  13 ALYAAGRHAEALALLDALLEHDPANREALHLAARCLHALERADAEHPAGSADIADTAHAPPDASPALATALLALGNRFYA 92
Cdd:COG3914    11 ALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  93 RKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDaahaeyr 172
Cdd:COG3914    91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE------- 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 173 hilerepdnlhannnlglllldlnrqpEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVV 252
Cdd:COG3914   164 ---------------------------EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216

                         250       260
                  ....*....|....*....|...
gi 1124707143 253 KGNLAMLLLRNGryaeGWPLYEA 275
Cdd:COG3914   217 HSNLLFALRQAC----DWEVYDR 235
Glycosyltransferase_GTB-type super family cl10013
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 305-522 1.81e-07

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


The actual alignment was detected with superfamily member cd03789:

Pssm-ID: 471961  Cd Length: 277  Bit Score: 52.73  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 305 SIIVWPEQGYGDDLQFCRYVTLLKARG-AARVSVACGPALGRLFKSLEHVDAVYVLDGQGTIPRHDYWCF---------- 373
Cdd:cd03789     1 KILVIRLSALGDVVLTTPLLRALKKAYpDAKITVVVGPGYAELLELNPYIDEVIPDDKRRRAGLRGRRKLlrelrarkyd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 374 -----MMSLPLRFGTTVETIPAPMPYLRAdaalaqsWRERLPARGFKVGVVWAGAprpqdpranaidqrRSTHARDWLP- 447
Cdd:cd03789    81 lvidlHSSLRSALLLLLSGAPRRIGFDRE-------KRRFLLNHPVKPLVVIPPG--------------ASGPAKRWPAe 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 448 -----ILRVPG----VRFVSLQKG-EATQPQIHALPAELRPLDPMDaaqDFADTAAIVDALDLVITVDTSMAHLAGALGK 517
Cdd:cd03789   140 rfaelADRLADegyrVVLFGGPAEeELAEEIAAALGARVVNLAGKT---SLRELAALLARADLVVGNDSGPMHLAAALGT 216


                  ....*
gi 1124707143 518 PVWIL 522
Cdd:cd03789   217 PTVAL 221
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-275 4.14e-32

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 131.27  E-value: 4.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  13 ALYAAGRHAEALALLDALLEHDPANREALHLAARCLHALERADAEHPAGSADIADTAHAPPDASPALATALLALGNRFYA 92
Cdd:COG3914    11 ALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  93 RKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDaahaeyr 172
Cdd:COG3914    91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE------- 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 173 hilerepdnlhannnlglllldlnrqpEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVV 252
Cdd:COG3914   164 ---------------------------EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216

                         250       260
                  ....*....|....*....|...
gi 1124707143 253 KGNLAMLLLRNGryaeGWPLYEA 275
Cdd:COG3914   217 HSNLLFALRQAC----DWEVYDR 235
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 33-268 1.23e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 77.43  E-value: 1.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  33 HDPANREALHLAARCLHALERADAEHpagsadiaDTAHAPPDASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPD 112
Cdd:TIGR02917 664 LKPDNTEAQIGLAQLLLAAKRTESAK--------KIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPS 735

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 113 wPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLL 192
Cdd:TIGR02917 736 -SQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLY 814

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1124707143 193 LDLNRqPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAE 268
Cdd:TIGR02917 815 LELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAE 889
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 109-245 1.60e-08

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 55.08  E-value: 1.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 109 IEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNL 188
Cdd:NF040959   66 IDPDDVEALYRLGVAYLKTGQYDRAIKVLEKVLSLAPDHVKAAYRKGVALLKIKDYEKAVEDLEEALEEKPDNFNLNYRL 145

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1124707143 189 GLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALAL 245
Cdd:NF040959  146 GLALDGLGQYDKAIEAFQKALELDPNEIKYHQAIGFMYVQKGDHETAAEHFKKAMEL 202
GT9_LPS_heptosyltransferase cd03789
lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide ...
 305-522 1.81e-07

lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340821  Cd Length: 277  Bit Score: 52.73  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 305 SIIVWPEQGYGDDLQFCRYVTLLKARG-AARVSVACGPALGRLFKSLEHVDAVYVLDGQGTIPRHDYWCF---------- 373
Cdd:cd03789     1 KILVIRLSALGDVVLTTPLLRALKKAYpDAKITVVVGPGYAELLELNPYIDEVIPDDKRRRAGLRGRRKLlrelrarkyd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 374 -----MMSLPLRFGTTVETIPAPMPYLRAdaalaqsWRERLPARGFKVGVVWAGAprpqdpranaidqrRSTHARDWLP- 447
Cdd:cd03789    81 lvidlHSSLRSALLLLLSGAPRRIGFDRE-------KRRFLLNHPVKPLVVIPPG--------------ASGPAKRWPAe 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 448 -----ILRVPG----VRFVSLQKG-EATQPQIHALPAELRPLDPMDaaqDFADTAAIVDALDLVITVDTSMAHLAGALGK 517
Cdd:cd03789   140 rfaelADRLADegyrVVLFGGPAEeELAEEIAAALGARVVNLAGKT---SLRELAALLARADLVVGNDSGPMHLAAALGT 216


                  ....*
gi 1124707143 518 PVWIL 522
Cdd:cd03789   217 PTVAL 221
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 106-245 2.86e-07

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 52.63  E-value: 2.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 106 ALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARsnlalLLWHTQRLDAAHAE--YR---HILEREPD 180
Cdd:cd24142    26 ALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEK-----YLYLGQLSGGEEALqyYEkgiEILEEELQ 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 181 NLHANNNLGLLLLDLNRQ--------------------PEAE----AAFRRALAADPSVPEAHNNLGNALNQQARTDEAI 236
Cdd:cd24142   101 ALQAASAEAEEEAEELKRklssalcalaeiymtdlcdePDAEqrceELITKALELDPTNPEALQTLASLRISQQRPDEAK 180


                  ....*....
gi 1124707143 237 AAYRQALAL 245
Cdd:cd24142   181 EALRRSLEL 189
TPR_1 pfam00515
Tetratricopeptide repeat;
216-249 4.65e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 46.26  E-value: 4.65e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1124707143 216 PEAHNNLGNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
RfaF COG0859
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis];
487-552 1.41e-06

ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440620  Cd Length: 336  Bit Score: 50.36  E-value: 1.41e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1124707143 487 DFADTAAIVDALDLVITVDTSMAHLAGALGKPVWILSRYDACWRWlrerdnSPWYPRARLFQQRAP 552
Cdd:COG0859   242 SLRELAALLARADLVVGNDTGPMHLAAALGTPTVALFGPTDPARW------GPYGDRHRVLRADLP 301
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 216-249 2.19e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.36  E-value: 2.19e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1124707143  216 PEAHNNLGNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 200-248 1.12e-05

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 48.54  E-value: 1.12e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1124707143  200 EAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:PRK11447   287 KAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPH 335
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 201-268 3.28e-05

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 45.62  E-value: 3.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1124707143 201 AEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAE 268
Cdd:NF033920  175 ALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQ 242
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 115-268 8.47e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 39.13  E-value: 8.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 115 SALGNLGLALRDQDRAAEAETVLRQALA------IAPDHA---GARSNLALLLWHTQRLDAAHAEYRHILEREPDnlhan 185
Cdd:NF040586  563 LSANNLARDLRELGRYAEALDLLEEALEryrevlGGPDHPdtlRAAKSLAVALRRAGRLEEALELAEDTYERYRR----- 637

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 186 nnlglllLDLNRQPEAEAAfRRALAADPSVpeahnnLGNALNQQARTDEAIAAYRQALALRPDYTVV-KGNLAMLLLRNG 264
Cdd:NF040586  638 -------RFGPDHPDTLAA-ALSLANDLRA------LGDADEARELAREVLDRYRRVLGEDHPFTLAcRNNLAVLLRALG 703


                  ....
gi 1124707143 265 RYAE 268
Cdd:NF040586  704 DPEE 707
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-275 4.14e-32

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 131.27  E-value: 4.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  13 ALYAAGRHAEALALLDALLEHDPANREALHLAARCLHALERADAEHPAGSADIADTAHAPPDASPALATALLALGNRFYA 92
Cdd:COG3914    11 ALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  93 RKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDaahaeyr 172
Cdd:COG3914    91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE------- 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 173 hilerepdnlhannnlglllldlnrqpEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVV 252
Cdd:COG3914   164 ---------------------------EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216

                         250       260
                  ....*....|....*....|...
gi 1124707143 253 KGNLAMLLLRNGryaeGWPLYEA 275
Cdd:COG3914   217 HSNLLFALRQAC----DWEVYDR 235
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
107-285 1.25e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 114.33  E-value: 1.25e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 107 LAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANN 186
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 187 NLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRY 266
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                         170
                  ....*....|....*....
gi 1124707143 267 AEGWPLYEARHDETVGEHA 285
Cdd:COG0457   161 EEALELLEKLEAAALAALL 179
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 87-274 1.40e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 97.88  E-value: 1.40e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  87 GNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDA 166
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 167 AHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALR 246
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180
                  ....*....|....*....|....*...
gi 1124707143 247 PDYTVVKGNLAMLLLRNGRYAEGWPLYE 274
Cdd:COG2956   175 PDCARALLLLAELYLEQGDYEEAIAALE 202
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 87-269 3.94e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 96.34  E-value: 3.94e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  87 GNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDA 166
Cdd:COG2956    49 GNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEK 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 167 AHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALR 246
Cdd:COG2956   129 AIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD 208

                         170       180
                  ....*....|....*....|...
gi 1124707143 247 PDYTVVKGNLAMLLLRNGRYAEG 269
Cdd:COG2956   209 PDYLPALPRLAELYEKLGDPEEA 231
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 90-274 1.34e-20

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 92.10  E-value: 1.34e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  90 FYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHA 169
Cdd:COG2956    86 YLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIE 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 170 EYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:COG2956   166 ALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD 245

                         170       180
                  ....*....|....*....|....*
gi 1124707143 250 TVVKgNLAMLLLRNGRYAEGWPLYE 274
Cdd:COG2956   246 DLLL-ALADLLERKEGLEAALALLE 269
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 105-275 1.45e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.83  E-value: 1.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 105 AALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHA 184
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 185 NNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNG 264
Cdd:COG3914    81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160

                         170
                  ....*....|.
gi 1124707143 265 RYAEGWPLYEA 275
Cdd:COG3914   161 RLEEAIAALRR 171
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 120-249 1.79e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 79.08  E-value: 1.79e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 120 LGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLLDLNRQP 199
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1124707143 200 EAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
34-246 1.17e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.67  E-value: 1.17e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  34 DPANREALHLAARCLHALERadaehPAGSADIADTAHAppdASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPDW 113
Cdd:COG0457     4 DPDDAEAYNNLGLAYRRLGR-----YEEAIEDYEKALE---LDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 114 PSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLL 193
Cdd:COG0457    76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1124707143 194 DLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALR 246
Cdd:COG0457   156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 87-246 4.23e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 78.62  E-value: 4.23e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  87 GNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDA 166
Cdd:COG2956   117 AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 167 AHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSvPEAHNNLGNALNQQARTDEAIAAYRQALALR 246
Cdd:COG2956   197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLRRH 275
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 132-248 3.16e-15

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 72.35  E-value: 3.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 132 EAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAA 211
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1124707143 212 DPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPA 117
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 33-268 1.23e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 77.43  E-value: 1.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  33 HDPANREALHLAARCLHALERADAEHpagsadiaDTAHAPPDASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPD 112
Cdd:TIGR02917 664 LKPDNTEAQIGLAQLLLAAKRTESAK--------KIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPS 735

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 113 wPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLL 192
Cdd:TIGR02917 736 -SQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLY 814

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1124707143 193 LDLNRqPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAE 268
Cdd:TIGR02917 815 LELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAE 889
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 9-174 1.25e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.96  E-value: 1.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143   9 LASHALYAAGRHAEALALLDALLEHDPANREALHLAARCLHALERadaehPAGSADIADTAHAppdASPALATALLALGN 88
Cdd:COG3914    83 LAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGR-----LEEALAALRRALA---LNPDFAEAYLNLGE 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  89 RFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAH 168
Cdd:COG3914   155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYD 234


                  ....*.
gi 1124707143 169 AEYRHI 174
Cdd:COG3914   235 RFEELL 240
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
200-274 2.90e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 65.58  E-value: 2.90e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1124707143 200 EAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIaAYRQALALRPDYTVVKGNLAMLLLRNGRYAEGWPLYE 274
Cdd:COG3063    10 EAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
90-180 4.59e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 65.19  E-value: 4.59e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  90 FYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETvLRQALAIAPDHAGARSNLALLLWHTQRLDAAHA 169
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|.
gi 1124707143 170 EYRHILEREPD 180
Cdd:COG3063    81 YLERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 87-180 7.74e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 65.80  E-value: 7.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  87 GNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDA 166
Cdd:COG4235    24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                          90
                  ....*....|....
gi 1124707143 167 AHAEYRHILEREPD 180
Cdd:COG4235   104 AIAAWQKLLALLPA 117
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
87-246 1.19e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.11  E-value: 1.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  87 GNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDA 166
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 167 AHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALR 246
Cdd:COG0457   163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQ 242
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 74-180 2.93e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 2.93e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  74 DASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSN 153
Cdd:COG4783    32 ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLR 111

                          90       100
                  ....*....|....*....|....*..
gi 1124707143 154 LALLLWHTQRLDAAHAEYRHILEREPD 180
Cdd:COG4783   112 LARAYRALGRPDEAIAALEKALELDPD 138
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 33-179 6.59e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.83  E-value: 6.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  33 HDPANREALHLAARCLHALERADAEHPAGSADIADTAHAPPDASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPD 112
Cdd:COG5010     7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN 86

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1124707143 113 WPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREP 179
Cdd:COG5010    87 NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 92-291 1.01e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.80  E-value: 1.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  92 ARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEY 171
Cdd:TIGR02917 613 AAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIA 692

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 172 RHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNnLGNALNQQARTDEAIAAYRQALALRPDYTV 251
Cdd:TIGR02917 693 KSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIK-LHRALLASGNTAEAVKTLEAWLKTHPNDAV 771

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1124707143 252 VKGNLAMLLLRNGRYAEGwplyeARHDETVGEHAVKLPPV 291
Cdd:TIGR02917 772 LRTALAELYLAQKDYDKA-----IKHYQTVVKKAPDNAVV 806
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 129-275 1.81e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 62.67  E-value: 1.81e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 129 RAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRA 208
Cdd:COG5010     1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1124707143 209 LAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAEGWPLYEA 275
Cdd:COG5010    81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
123-248 9.10e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 58.64  E-value: 9.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 123 ALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAhaeyrhilerepdnlhannnlglllldlnrqpeae 202
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA----------------------------------- 45

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1124707143 203 AAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:COG3063    46 IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
116-268 9.28e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 61.85  E-value: 9.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 116 ALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILER------EPDNLHANNNLG 189
Cdd:COG4785     1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERidralaLPDLAQLYYERG 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1124707143 190 LLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAE 268
Cdd:COG4785    81 VAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 94-275 1.51e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.87  E-value: 1.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  94 KQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRH 173
Cdd:TIGR02917 581 GQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKR 660

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 174 ILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRP-DYTVV 252
Cdd:TIGR02917 661 ALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPsSQNAI 740

                         170       180
                  ....*....|....*....|...
gi 1124707143 253 KgnLAMLLLRNGRYAEGWPLYEA 275
Cdd:TIGR02917 741 K--LHRALLASGNTAEAVKTLEA 761
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 95-247 1.67e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.89  E-value: 1.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  95 QAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHI 174
Cdd:COG5010     1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1124707143 175 LEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRP 247
Cdd:COG5010    81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
8-244 4.08e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 57.23  E-value: 4.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143   8 PLASHALYAAGRHAEALALLDALLEHDPANREALHLAARCLHALERADAehpaGSADIADTAHAPPDaspaLATALLALG 87
Cdd:COG4785     9 LLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAA----LAAERIDRALALPD----LAQLYYERG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  88 NRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAA 167
Cdd:COG4785    81 VAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1124707143 168 HAEYRHILEREPDNLHANNNLGLLlldlnrqpEAEAAFRRALAADPSVPeahnnlGNALNQQARTDEAIAAYRQALA 244
Cdd:COG4785   161 IADLEKALELDPNDPERALWLYLA--------ERKLDPEKALALLLEDW------ATAYLLQGDTEEARELFKLALA 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 93-248 4.59e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 59.33  E-value: 4.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  93 RKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYR 172
Cdd:TIGR02917 444 SGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFE 523

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1124707143 173 HILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:TIGR02917 524 KVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 92-248 7.18e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 7.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  92 ARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEY 171
Cdd:TIGR02917 477 GKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWL 556

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1124707143 172 RHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:TIGR02917 557 EKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPD 633
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 109-245 1.60e-08

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 55.08  E-value: 1.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 109 IEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNL 188
Cdd:NF040959   66 IDPDDVEALYRLGVAYLKTGQYDRAIKVLEKVLSLAPDHVKAAYRKGVALLKIKDYEKAVEDLEEALEEKPDNFNLNYRL 145

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1124707143 189 GLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALAL 245
Cdd:NF040959  146 GLALDGLGQYDKAIEAFQKALELDPNEIKYHQAIGFMYVQKGDHETAAEHFKKAMEL 202
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
51-248 1.94e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.92  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  51 LERADAEHPAGSADIADTAHAPPDASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPDWPSALG---------NLG 121
Cdd:COG4785     1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALAlpdlaqlyyERG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 122 LALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAhaeyrhilerepdnlhannnlglllldlnrqpea 201
Cdd:COG4785    81 VAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAA---------------------------------- 126

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1124707143 202 EAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:COG4785   127 LEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN 173
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 89-277 2.46e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 2.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  89 RFYARKQAAQAEHAW-RAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAA 167
Cdd:TIGR02917 541 GLYLRTGNEEEAVAWlEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKA 620

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 168 HAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRP 247
Cdd:TIGR02917 621 VSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHP 700

                         170       180       190
                  ....*....|....*....|....*....|
gi 1124707143 248 DYTVVKGNLAMLLLRNGRYAEGWPLYEARH 277
Cdd:TIGR02917 701 KAALGFELEGDLYLRQKDYPAAIQAYRKAL 730
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 9-275 6.01e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.86  E-value: 6.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143   9 LASHALYAAGRHAEALALLDALLEHDPANREALHLAARCLHALERADaehpagsaDIADTAHAPPDASPALATALLALGN 88
Cdd:TIGR02917 300 LAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVD--------EAIATLSPALGLDPDDPAALSLLGE 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  89 RFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDhaGARSNLALLLWH--TQRLDA 166
Cdd:TIGR02917 372 AYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPE--LGRADLLLILSYlrSGQFDK 449

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 167 AHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALR 246
Cdd:TIGR02917 450 ALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTID 529

                         250       260
                  ....*....|....*....|....*....
gi 1124707143 247 PDYTVVKGNLAMLLLRNGRYAEGWPLYEA 275
Cdd:TIGR02917 530 PKNLRAILALAGLYLRTGNEEEAVAWLEK 558
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 34-269 1.36e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  34 DPANREALHLAARCLHALERadaehPAGSADIADTAHAppdASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPDW 113
Cdd:TIGR02917 155 DPRSLYAKLGLAQLALAENR-----FDEARALIDEVLT---ADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNN 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 114 PSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLL 193
Cdd:TIGR02917 227 IAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEY 306

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1124707143 194 DLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAEG 269
Cdd:TIGR02917 307 QLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKA 382
GT9_LPS_heptosyltransferase cd03789
lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide ...
 305-522 1.81e-07

lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340821  Cd Length: 277  Bit Score: 52.73  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 305 SIIVWPEQGYGDDLQFCRYVTLLKARG-AARVSVACGPALGRLFKSLEHVDAVYVLDGQGTIPRHDYWCF---------- 373
Cdd:cd03789     1 KILVIRLSALGDVVLTTPLLRALKKAYpDAKITVVVGPGYAELLELNPYIDEVIPDDKRRRAGLRGRRKLlrelrarkyd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 374 -----MMSLPLRFGTTVETIPAPMPYLRAdaalaqsWRERLPARGFKVGVVWAGAprpqdpranaidqrRSTHARDWLP- 447
Cdd:cd03789    81 lvidlHSSLRSALLLLLSGAPRRIGFDRE-------KRRFLLNHPVKPLVVIPPG--------------ASGPAKRWPAe 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 448 -----ILRVPG----VRFVSLQKG-EATQPQIHALPAELRPLDPMDaaqDFADTAAIVDALDLVITVDTSMAHLAGALGK 517
Cdd:cd03789   140 rfaelADRLADegyrVVLFGGPAEeELAEEIAAALGARVVNLAGKT---SLRELAALLARADLVVGNDSGPMHLAAALGT 216


                  ....*
gi 1124707143 518 PVWIL 522
Cdd:cd03789   217 PTVAL 221
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 148-268 2.51e-07

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 51.95  E-value: 2.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 148 AGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALN 227
Cdd:TIGR02521  31 AKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLC 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1124707143 228 QQARTDEAIAAYRQALALrPDYTVVKG---NLAMLLLRNGRYAE 268
Cdd:TIGR02521 111 QQGKYEQAMQQFEQAIED-PLYPQPARsleNAGLCALKAGDFDK 153
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 106-245 2.86e-07

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 52.63  E-value: 2.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 106 ALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARsnlalLLWHTQRLDAAHAE--YR---HILEREPD 180
Cdd:cd24142    26 ALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEK-----YLYLGQLSGGEEALqyYEkgiEILEEELQ 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 181 NLHANNNLGLLLLDLNRQ--------------------PEAE----AAFRRALAADPSVPEAHNNLGNALNQQARTDEAI 236
Cdd:cd24142   101 ALQAASAEAEEEAEELKRklssalcalaeiymtdlcdePDAEqrceELITKALELDPTNPEALQTLASLRISQQRPDEAK 180


                  ....*....
gi 1124707143 237 AAYRQALAL 245
Cdd:cd24142   181 EALRRSLEL 189
TPR_1 pfam00515
Tetratricopeptide repeat;
216-249 4.65e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 46.26  E-value: 4.65e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1124707143 216 PEAHNNLGNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
RfaF COG0859
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis];
487-552 1.41e-06

ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440620  Cd Length: 336  Bit Score: 50.36  E-value: 1.41e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1124707143 487 DFADTAAIVDALDLVITVDTSMAHLAGALGKPVWILSRYDACWRWlrerdnSPWYPRARLFQQRAP 552
Cdd:COG0859   242 SLRELAALLARADLVVGNDTGPMHLAAALGTPTVALFGPTDPARW------GPYGDRHRVLRADLP 301
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 216-249 2.19e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.36  E-value: 2.19e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1124707143  216 PEAHNNLGNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 65-249 2.61e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.47  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  65 IADTAHAPPDASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPDWPSALgnLGLA--LRDQDRAAEAETVLRQALA 142
Cdd:TIGR02917 110 LDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAK--LGLAqlALAENRFDEARALIDEVLT 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 143 IAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNL 222
Cdd:TIGR02917 188 ADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLK 267

                         170       180
                  ....*....|....*....|....*..
gi 1124707143 223 GNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:TIGR02917 268 ALVDFQKKNYEDARETLQDALKSAPEY 294
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 34-151 6.72e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.77  E-value: 6.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  34 DPANREALHLAARCLHALERADAehpagSADIADTAHAppdASPALATALLALGNRFYARKQAAQAEHAWRAALAIEPDW 113
Cdd:COG4235    13 NPNDAEGWLLLGRAYLRLGRYDE-----ALAAYEKALR---LDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDN 84

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1124707143 114 PSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGAR 151
Cdd:COG4235    85 PEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 200-248 1.12e-05

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 48.54  E-value: 1.12e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1124707143  200 EAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:PRK11447   287 KAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPH 335
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 95-248 1.27e-05

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 48.16  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143   95 QAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGaRSNLALLLwHTQRLDAAHAEYRHI 174
Cdd:PRK11447   284 QGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPHSSN-RDKWESLL-KVNRYWLLIQQGDAA 361

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1124707143  175 LErepdnlhannnlglllldLNRQPEAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:PRK11447   362 LK------------------ANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPG 417
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 201-268 3.28e-05

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 45.62  E-value: 3.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1124707143 201 AEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAE 268
Cdd:NF033920  175 ALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQ 242
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 106-268 3.75e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 3.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 106 ALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQAL-------AIAPDHA------------------------------ 148
Cdd:TIGR02917  48 ALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALslgypknQVLPLLArayllqgkfqqvldelpgktllddegaael 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 149 -GARSNLALLLwhtQRLDAAHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAFRRALAADPSVPEAHNNLGNALN 227
Cdd:TIGR02917 128 lALRGLAYLGL---GQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLL 204

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1124707143 228 QQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAE 268
Cdd:TIGR02917 205 SLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 197-268 4.59e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.06  E-value: 4.59e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1124707143 197 RQPEAEAAFRRALAADPS---VPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKG---NLAMLLLRNGRYAE 268
Cdd:COG1729     8 DYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDallKLGLSYLELGDYDK 85
TPR_11 pfam13414
TPR repeat;
223-264 4.88e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.53  E-value: 4.88e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1124707143 223 GNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNG 264
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
225-275 1.15e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.15e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1124707143 225 ALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAEGWPLYEA 275
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKA 51
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
87-146 1.44e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.44e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  87 GNRFYARKQAAQAEhAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPD 146
Cdd:COG3063    33 GLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 87-268 1.65e-04

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 43.48  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  87 GNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDA 166
Cdd:TIGR02521  38 ALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQ 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 167 AHAEYRHILErEPDNLHANNNLGLLLLDLNRQP---EAEAAFRRALAADPSVPEAHNNLgnalnqqARTDEAIAAYRQAL 243
Cdd:TIGR02521 118 AMQQFEQAIE-DPLYPQPARSLENAGLCALKAGdfdKAEKYLTRALQIDPQRPESLLEL-------AELYYLRGQYKDAR 189

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1124707143 244 ALRPDYTVVKGNLA-MLLL------RNGRYAE 268
Cdd:TIGR02521 190 AYLERYQQTYNQTAeSLWLgiriarALGDVAA 221
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 200-253 1.77e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 43.77  E-value: 1.77e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1124707143 200 EAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVK 253
Cdd:cd24142    18 LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEK 71
TPR_19 pfam14559
Tetratricopeptide repeat;
127-180 3.25e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.10  E-value: 3.25e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1124707143 127 QDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPD 180
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPD 54
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 91-175 6.62e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 6.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  91 YARKQAAQA-EHAWRAaLAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHA 169
Cdd:TIGR02917 814 YLELKDPRAlEYAERA-LKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARK 892


                  ....*.
gi 1124707143 170 EYRHIL 175
Cdd:TIGR02917 893 ELDKLL 898
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 122-248 7.77e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 7.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 122 LALRDQDRAAEAETVLRQALAIAPDH---AGARSNLALLLWHTQRLDAAHAEYRHILEREPDnlhannnlglllldlnrq 198
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPD------------------ 62

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1124707143 199 peaeaafrralaaDPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:COG1729    63 -------------SPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
TPR_8 pfam13181
Tetratricopeptide repeat;
217-248 7.89e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.99  E-value: 7.89e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1124707143 217 EAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_19 pfam14559
Tetratricopeptide repeat;
200-259 1.43e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.18  E-value: 1.43e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 200 EAEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAML 259
Cdd:pfam14559   6 EALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 200-249 1.76e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.93  E-value: 1.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1124707143 200 EAEAAFRRALAADPSVP---EAHNNLGNALNQQARTDEAIAAYRQALALRPDY 249
Cdd:pfam13432  15 DAAAALEAALARFPESPdaaAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
200-275 2.68e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.87  E-value: 2.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 200 EAEAAFRRAlaadpsvPEAHN--NLGNALNQQARTDEAIAAYRQALA--LRPDYTVVKGnLAMLLLRNGRYAEGWPLYEA 275
Cdd:COG4700    78 ELEKALEFA-------DTVQNrvRLADALLELGRYDEAIELYEEALTgiFADDPHILLG-LAQALFELGRYAEALETLEK 149
TPR_12 pfam13424
Tetratricopeptide repeat;
214-274 2.78e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.98  E-value: 2.78e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1124707143 214 SVPEAHNNLGNALNQQARTDEAIAAYRQALAL--------RPDYTVVKGNLAMLLLRNGRYAEGWPLYE 274
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLE 69
TPR_12 pfam13424
Tetratricopeptide repeat;
146-248 3.16e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.60  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 146 DHAGARSNLALLLWHTQRLDAAHAEYRHILERepdnlhannnlglllldlnrqpeaeaaFRRALAAD-PSVPEAHNNLGN 224
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEI---------------------------ARRLLGPDhPLTATTLLNLGR 53

                          90       100
                  ....*....|....*....|....
gi 1124707143 225 ALNQQARTDEAIAAYRQALALRPD 248
Cdd:pfam13424  54 LYLELGRYEEALELLERALALAEK 77
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 216-248 3.26e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.19  E-value: 3.26e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1124707143 216 PEAHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_7 pfam13176
Tetratricopeptide repeat;
218-248 3.32e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.21  E-value: 3.32e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1124707143 218 AHNNLGNALNQQARTDEAIAAYRQALALRPD 248
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKD 31
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 201-275 3.37e-03

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 39.24  E-value: 3.37e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1124707143 201 AEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTVVKGNLAMLLLRNGRYAEGWPLYEA 275
Cdd:TIGR02521  50 AKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQFEQ 124
TPR_17 pfam13431
Tetratricopeptide repeat;
204-237 3.61e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.21  E-value: 3.61e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1124707143 204 AFRRALAADPSVPEAHNNLGNALNQQARTDEAIA 237
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 90-180 3.62e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 3.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  90 FYARKQAAQAEHAWRAALAIEPDW---PSALGNLGLALRDQDRAAEAETVLRQALAIAPDH---AGARSNLALLLWHTQR 163
Cdd:COG1729     3 LLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGD 82

                          90
                  ....*....|....*..
gi 1124707143 164 LDAAHAEYRHILEREPD 180
Cdd:COG1729    83 YDKARATLEELIKKYPD 99
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
119-275 4.28e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.09  E-value: 4.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 119 NLGLALRDQDRAAEAETVLRQALA-IAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDnlhannnlglllldlnr 197
Cdd:COG4700    94 RLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPD----------------- 156

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1124707143 198 qpeaeaaFRRalaadpsvPEAHNNLGNALNQQARTDEAIAAYRQALALRPDYTvVKGNLAMLLLRNGRYAEGWPLYEA 275
Cdd:COG4700   157 -------FKS--------SDAHLLYARALEALGDLEAAEAELEALARRYSGPE-ARYRYAKFLARQGRTAEAKELLEE 218
TPR_12 pfam13424
Tetratricopeptide repeat;
90-146 5.70e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.83  E-value: 5.70e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1124707143  90 FYARKQAAQAEHAWRAALAI-----EPDWPS---ALGNLGLALRDQDRAAEAETVLRQALAIAPD 146
Cdd:pfam13424  13 LRRLGRYDEALELLEKALEIarrllGPDHPLtatTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_11 pfam13414
TPR repeat;
197-229 6.06e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 34.75  E-value: 6.06e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1124707143 197 RQPEAEAAFRRALAADPSVPEAHNNLGNALNQQ 229
Cdd:pfam13414   9 KYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 87-247 7.02e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 39.30  E-value: 7.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143   87 GNRFYARKQAAQAEHAWRAALAIEPDWPSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLAlLLWHTQRLDA 166
Cdd:PRK11447   358 GDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPGNTNAVRGLA-NLYRQQSPEK 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143  167 AHAeYRHILEREPDNLHANNNLGLLLLDLNRQPE----------AEAAFRRALAADPSVPEAHNNLGNALNQQARTDEAI 236
Cdd:PRK11447   437 ALA-FIASLSASQRRSIDDIERSLQNDRLAQQAEalenqgkwaqAAELQRQRLALDPGSVWLTYRLAQDLRQAGQRSQAD 515

                          170
                   ....*....|.
gi 1124707143  237 AAYRQALALRP 247
Cdd:PRK11447   516 ALMRRLAQQKP 526
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 126-245 7.37e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 39.20  E-value: 7.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 126 DQDRAAEAETVLRQALAIAPDHAGARSNLALLLWHTQRLDAAHAEYRHILEREPDNLHANNNLGLLLLDLNRQPEAEAAF 205
Cdd:TIGR00990 377 ELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATF 456

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1124707143 206 RRALAADPSVPEAHNNLGNALNQQARTDEAIAAYRQALAL 245
Cdd:TIGR00990 457 RRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIEL 496
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 87-157 8.16e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.51  E-value: 8.16e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1124707143  87 GNRFYARKQAAQAEHAWRAALAIEPDW---PSALGNLGLALRDQDRAAEAETVLRQALAIAPDHAGARSNLALL 157
Cdd:COG1729    37 GEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKEARARL 110
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 115-268 8.47e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 39.13  E-value: 8.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 115 SALGNLGLALRDQDRAAEAETVLRQALA------IAPDHA---GARSNLALLLWHTQRLDAAHAEYRHILEREPDnlhan 185
Cdd:NF040586  563 LSANNLARDLRELGRYAEALDLLEEALEryrevlGGPDHPdtlRAAKSLAVALRRAGRLEEALELAEDTYERYRR----- 637

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124707143 186 nnlglllLDLNRQPEAEAAfRRALAADPSVpeahnnLGNALNQQARTDEAIAAYRQALALRPDYTVV-KGNLAMLLLRNG 264
Cdd:NF040586  638 -------RFGPDHPDTLAA-ALSLANDLRA------LGDADEARELAREVLDRYRRVLGEDHPFTLAcRNNLAVLLRALG 703


                  ....
gi 1124707143 265 RYAE 268
Cdd:NF040586  704 DPEE 707
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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