NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1119472667|ref|WP_072446310|]
View 

tetratricopeptide repeat protein [Pseudomonas sp. NFPP02]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 284-448 6.44e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.01  E-value: 6.44e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 284 QLGMLDSAQALRDDGQRLRLDTWADQGYWLLLPLLLLAACAGRRGWLFCLPLLLMGAPQPSYAFGLQDLWL--------R 355
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAaallllaaL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 356 PDQQGQYLLKHKRPAEAAEHFQ-----DPQWQ------GVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAG 419
Cdd:COG3914    81 LELAALLLQALGRYEEALALYRralalNPDNAealfnlGNLLLALGRLEEALAALRRalalnPDFAEAYLNLGEALRRLG 160

                         170       180
                  ....*....|....*....|....*....
gi 1119472667 420 EFEAALDAYEQALEAQPDLQPALKNKALV 448
Cdd:COG3914   161 RLEEAIAALRRALELDPDNAEALNNLGNA 189
vWFA super family cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation ...
 95-161 6.65e-08

Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.


The actual alignment was detected with superfamily member cd01467:

Pssm-ID: 469594 [Multi-domain]  Cd Length: 180  Bit Score: 52.72  E-value: 6.65e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1119472667  95 LVVLLELTPEMLATD-SPPNRLEQARRKLYDLLQARTDAQTAIIVYAGSAHTLVPLSDDLATSRNLLE 161
Cdd:cd01467     5 IMIALDVSGSMLAQDfVKPSRLEAAKEVLSDFIDRRENDRIGLVVFAGAAFTQAPLTLDRESLKELLE 72
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 284-448 6.44e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.01  E-value: 6.44e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 284 QLGMLDSAQALRDDGQRLRLDTWADQGYWLLLPLLLLAACAGRRGWLFCLPLLLMGAPQPSYAFGLQDLWL--------R 355
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAaallllaaL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 356 PDQQGQYLLKHKRPAEAAEHFQ-----DPQWQ------GVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAG 419
Cdd:COG3914    81 LELAALLLQALGRYEEALALYRralalNPDNAealfnlGNLLLALGRLEEALAALRRalalnPDFAEAYLNLGEALRRLG 160

                         170       180
                  ....*....|....*....|....*....
gi 1119472667 420 EFEAALDAYEQALEAQPDLQPALKNKALV 448
Cdd:COG3914   161 RLEEAIAALRRALELDPDNAEALNNLGNA 189
vWA_BatA_type cd01467
VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood ...
 95-161 6.65e-08

VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup are bacterial in origin. They are typified by the presence of a MIDAS motif.


Pssm-ID: 238744 [Multi-domain]  Cd Length: 180  Bit Score: 52.72  E-value: 6.65e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1119472667  95 LVVLLELTPEMLATD-SPPNRLEQARRKLYDLLQARTDAQTAIIVYAGSAHTLVPLSDDLATSRNLLE 161
Cdd:cd01467     5 IMIALDVSGSMLAQDfVKPSRLEAAKEVLSDFIDRRENDRIGLVVFAGAAFTQAPLTLDRESLKELLE 72
TPR_1 pfam00515
Tetratricopeptide repeat;
405-437 7.47e-08

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 48.57  E-value: 7.47e-08
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119472667 405 AYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
VWA_2 pfam13519
von Willebrand factor type A domain;
105-165 2.27e-07

von Willebrand factor type A domain;


Pssm-ID: 463909 [Multi-domain]  Cd Length: 103  Bit Score: 49.21  E-value: 2.27e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119472667 105 MLATDSPPNRLEQARRKLYDLLQARTDAQTAIIVYAGSAHTLVPLSDDLATSRNLLEALRP 165
Cdd:pfam13519  11 MRNGDYGPTRLEAAKDAVLALLKSLPGDRVGLVTFGDGPEVLIPLTKDRAKILRALRRLEP 71
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 405-437 6.52e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 45.90  E-value: 6.52e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1119472667  405 AYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 367-448 5.55e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 46.97  E-value: 5.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 367 KRPAEAAEHFQDpqwqGVALYEAGNYAEAIKRFAQG--------SDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDL 438
Cdd:PRK02603   30 KKAKEAFVYYRD----GMSAQADGEYAEALENYEEAlkleedpnDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQ 105

                          90
                  ....*....|
gi 1119472667 439 QPALKNKALV 448
Cdd:PRK02603  106 PSALNNIAVI 115
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 284-448 6.44e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.01  E-value: 6.44e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 284 QLGMLDSAQALRDDGQRLRLDTWADQGYWLLLPLLLLAACAGRRGWLFCLPLLLMGAPQPSYAFGLQDLWL--------R 355
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAaallllaaL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 356 PDQQGQYLLKHKRPAEAAEHFQ-----DPQWQ------GVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAG 419
Cdd:COG3914    81 LELAALLLQALGRYEEALALYRralalNPDNAealfnlGNLLLALGRLEEALAALRRalalnPDFAEAYLNLGEALRRLG 160

                         170       180
                  ....*....|....*....|....*....
gi 1119472667 420 EFEAALDAYEQALEAQPDLQPALKNKALV 448
Cdd:COG3914   161 RLEEAIAALRRALELDPDNAEALNNLGNA 189
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
360-454 2.85e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.79  E-value: 2.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 360 GQYLLKHKRPAEAAEHFQ-----DPQ------WQGVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEFEA 423
Cdd:COG0457    49 GLAYLRLGRYEEALADYEqalelDPDdaealnNLGLALQALGRYEEALEDYDKAleldpDDAEALYNLGLALLELGRYDE 128

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1119472667 424 ALDAYEQALEAQPDLQPALKNKALVEALMQE 454
Cdd:COG0457   129 AIEAYERALELDPDDADALYNLGIALEKLGR 159
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 272-442 1.30e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.78  E-value: 1.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 272 YRAARLDDKDLRQLGMLDSAQALRDDGQRLRLDTWADQGYWLLLPLLLLAACAGRRGWLFCLPLLLMGAPQPSYAFGLQD 351
Cdd:COG3914    25 ELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRA 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 352 LWLRPDQQGQY------LLKHKRPAEAAEHFQ-----DPQW------QGVALYEAGNYAEAIKRFAQG-----SDAYSHY 409
Cdd:COG3914   105 LALNPDNAEALfnlgnlLLALGRLEEALAALRralalNPDFaeaylnLGEALRRLGRLEEAIAALRRAleldpDNAEALN 184

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1119472667 410 NRGNALAKAGEFEAALDAYEQALEAQPDLQPAL 442
Cdd:COG3914   185 NLGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
383-448 3.24e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 3.24e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119472667 383 GVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDLQPALKNKALV 448
Cdd:COG0457    15 GLAYRRLGRYEEAIEDYEKAleldpDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
357-448 7.54e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 56.46  E-value: 7.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 357 DQQGQYLLKHKRPAEAAEHFQdpqwQGVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAGEFEAALDAYEQA 431
Cdd:COG4785    58 LAAERIDRALALPDLAQLYYE----RGVAYDSLGDYDLAIADFDQaleldPDLAEAYNNRGLAYLLLGDYDAALEDFDRA 133

                          90
                  ....*....|....*..
gi 1119472667 432 LEAQPDLQPALKNKALV 448
Cdd:COG4785   134 LELDPDYAYAYLNRGIA 150
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 333-457 2.92e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 2.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 333 LPLLLMGAPQPSYAFGLQDLWLRPDQQGQYLLKHKRPAEAAEHFQDPQWQGVALYEAGNYAEAIKRFAQG-----SDAYS 407
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAlqldpNNPEL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1119472667 408 HYNRGNALAKAGEFEAALDAYEQALEAQPDLQPALKNKALVEALMQEQTQ 457
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDE 140
vWA_BatA_type cd01467
VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood ...
 95-161 6.65e-08

VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup are bacterial in origin. They are typified by the presence of a MIDAS motif.


Pssm-ID: 238744 [Multi-domain]  Cd Length: 180  Bit Score: 52.72  E-value: 6.65e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1119472667  95 LVVLLELTPEMLATD-SPPNRLEQARRKLYDLLQARTDAQTAIIVYAGSAHTLVPLSDDLATSRNLLE 161
Cdd:cd01467     5 IMIALDVSGSMLAQDfVKPSRLEAAKEVLSDFIDRRENDRIGLVVFAGAAFTQAPLTLDRESLKELLE 72
TPR_1 pfam00515
Tetratricopeptide repeat;
405-437 7.47e-08

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 48.57  E-value: 7.47e-08
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119472667 405 AYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 363-451 9.91e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 50.38  E-value: 9.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 363 LLKHKRPAEAAEHFQD-----PQ---------WQGVALYEAGNYAEAIKRFAQGSDAY--------SHYNRGNALAKAGE 420
Cdd:COG1729     3 LLKAGDYDEAIAAFKAflkryPNsplapdalyWLGEAYYALGDYDEAAEAFEKLLKRYpdspkapdALLKLGLSYLELGD 82

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1119472667 421 FEAALDAYEQALEAQPDLQPALKNKALVEAL 451
Cdd:COG1729    83 YDKARATLEELIKKYPDSEAAKEARARLARL 113
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 358-454 1.76e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.58  E-value: 1.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 358 QQGQYLLKHKRPAEAAEHFQ-----DPQ------WQGVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEF 421
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEkalelDPDnpeafaLLGEILLQLGDLDEAIVLLHEAleldpDEPEARLNLGLALLKAGDY 88

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1119472667 422 EAALDAYEQALEAQPDLQPALKNKALVEALMQE 454
Cdd:COG4783    89 DEALALLEKALKLDPEHPEAYLRLARAYRALGR 121
VWA_2 pfam13519
von Willebrand factor type A domain;
105-165 2.27e-07

von Willebrand factor type A domain;


Pssm-ID: 463909 [Multi-domain]  Cd Length: 103  Bit Score: 49.21  E-value: 2.27e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119472667 105 MLATDSPPNRLEQARRKLYDLLQARTDAQTAIIVYAGSAHTLVPLSDDLATSRNLLEALRP 165
Cdd:pfam13519  11 MRNGDYGPTRLEAAKDAVLALLKSLPGDRVGLVTFGDGPEVLIPLTKDRAKILRALRRLEP 71
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
383-450 6.31e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 50.68  E-value: 6.31e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1119472667 383 GVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDLQPALKNKALVEA 450
Cdd:COG4785   114 GLAYLLLGDYDAALEDFDRAleldpDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAER 186
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 405-437 6.52e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 45.90  E-value: 6.52e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1119472667  405 AYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
360-473 1.17e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.01  E-value: 1.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 360 GQYLLKHKRPAEAAEHFQ-----DPQ------WQGVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEFEA 423
Cdd:COG0457    83 GLALQALGRYEEALEDYDkalelDPDdaealyNLGLALLELGRYDEAIEAYERAleldpDDADALYNLGIALEKLGRYEE 162

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1119472667 424 ALDAYEQALEAQPDLQPALKNKALVEALMQEQTQPEPDPPAKNADDETAQ 473
Cdd:COG0457   163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 384-437 4.49e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.75  E-value: 4.49e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1119472667 384 VALYEAGNYAEAIKRFAQGSDAY--------SHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYpnsplapdALYWLGEAYYALGDYDEAAEAFEKLLKRYPD 62
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 360-437 4.58e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 4.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 360 GQYLLKHKRPAEAAEHFQ-----DPQ------WQGVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEFEA 423
Cdd:COG4783    45 GEILLQLGDLDEAIVLLHealelDPDepearlNLGLALLKAGDYDEALALLEKAlkldpEHPEAYLRLARAYRALGRPDE 124

                          90
                  ....*....|....
gi 1119472667 424 ALDAYEQALEAQPD 437
Cdd:COG4783   125 AIAALEKALELDPD 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
385-457 5.02e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.16  E-value: 5.02e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1119472667 385 ALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEFEAALdAYEQALEAQPDLQPALKNKALVEALMQEQTQ 457
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKAleldpDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDE 77
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 367-448 5.55e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 46.97  E-value: 5.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 367 KRPAEAAEHFQDpqwqGVALYEAGNYAEAIKRFAQG--------SDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDL 438
Cdd:PRK02603   30 KKAKEAFVYYRD----GMSAQADGEYAEALENYEEAlkleedpnDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQ 105

                          90
                  ....*....|
gi 1119472667 439 QPALKNKALV 448
Cdd:PRK02603  106 PSALNNIAVI 115
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 405-437 6.70e-06

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 42.90  E-value: 6.70e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119472667 405 AYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 360-451 1.24e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.00  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 360 GQYLLKHKRPAEAAEHFQ--------DPQWQ---GVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAGEFEA 423
Cdd:COG4235    24 GRAYLRLGRYDEALAAYEkalrldpdNADALldlAEALLAAGDTEEAEELLERalaldPDNPEALYLLGLAAFQQGDYAE 103

                          90       100
                  ....*....|....*....|....*...
gi 1119472667 424 ALDAYEQALEAQPDLQPALKNKALVEAL 451
Cdd:COG4235   104 AIAAWQKLLALLPADAPARLLEASIAEA 131
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 383-454 1.57e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.61  E-value: 1.57e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1119472667 383 GVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDLQPALKNKALVEALMQE 454
Cdd:COG4235    24 GRAYLRLGRYDEALAAYEKalrldPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGD 100
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
362-439 6.86e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 6.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 362 YLLKHKRPAEAAEHFQ-----DPQ------WQGVALYEAGNYAEAIK----RFAQGSDAYSHYNRGNALAKAGEFEAALD 426
Cdd:COG3063     1 LYLKLGDLEEAEEYYEkalelDPDnadalnNLGLLLLEQGRYDEAIAlekaLKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|...
gi 1119472667 427 AYEQALEAQPDLQ 439
Cdd:COG3063    81 YLERALELDPSAL 93
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
404-448 1.43e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 1.43e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1119472667 404 DAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDLQPALKNKALV 448
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLA 51
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
363-433 1.67e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 43.33  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 363 LLKHKRPAEAAEHFQ---------DPQ--WQ-GVALYEAGNYAEAIK------------RFAQGSDAYshynrGNALAKA 418
Cdd:COG4700    99 LLELGRYDEAIELYEealtgifadDPHilLGlAQALFELGRYAEALEtlekliaknpdfKSSDAHLLY-----ARALEAL 173

                          90
                  ....*....|....*
gi 1119472667 419 GEFEAALDAYEQALE 433
Cdd:COG4700   174 GDLEAAEAELEALAR 188
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 383-453 2.03e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.56  E-value: 2.03e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1119472667 383 GVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDLQPALKNkaLVEALMQ 453
Cdd:COG2956   151 AELYLEQGDYDEAIEALEKAlkldpDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPR--LAELYEK 224
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 360-457 2.54e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.18  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 360 GQYLLKHKRPAEAAEHFQ----------DPQWQGVALYEA-GNYAEAIKRF-----AQGSDAYSHYNRGNALAKAGEFEA 423
Cdd:COG2956    83 AQDYLKAGLLDRAEELLEklleldpddaEALRLLAEIYEQeGDWEKAIEVLerllkLGPENAHAYCELAELYLEQGDYDE 162

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1119472667 424 ALDAYEQALEAQPDLQPALKNKALVEALMQEQTQ 457
Cdd:COG2956   163 AIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196
ycf3 CHL00033
photosystem I assembly protein Ycf3
 390-448 2.67e-04

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 41.92  E-value: 2.67e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1119472667 390 GNYAEAIKRFAQG----SDAY--SH--YNRGNALAKAGEFEAALDAYEQALEAQPDLQPALKNKALV 448
Cdd:CHL00033   49 GEYAEALQNYYEAmrleIDPYdrSYilYNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVI 115
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
354-454 3.64e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.21  E-value: 3.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 354 LRPDQQGQYLLKHKRPAEAAEHFQDPQWQGVALYEAGNYAEAIKRFAQGS------------DAYSHYNRGNALAKAGEF 421
Cdd:COG4785    10 LALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAaeridralalpdLAQLYYERGVAYDSLGDY 89

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1119472667 422 EAALDAYEQALEAQPDLQPALKNKALVEALMQE 454
Cdd:COG4785    90 DLAIADFDQALELDPDLAEAYNNRGLAYLLLGD 122
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 382-437 3.81e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.86  E-value: 3.81e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1119472667 382 QGVALYEAGNYAEAIKRFAQ--------GSDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAalarfpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 307-436 4.48e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 4.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 307 ADQGYWLLLPLLLLAACAGRRGWLFCLPLLLMGAPQPSYAFGLQDLWLRPDQQGQYLLKHKRPAEAAEHFQ-----DPQW 381
Cdd:COG5010     8 DRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEqalqlDPNN 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1119472667 382 Q------GVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAGEFEAALDAYEQALEAQP 436
Cdd:COG5010    88 PelyynlALLYSRSGDKDEAKEYYEKalalsPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 358-440 5.39e-04

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 41.38  E-value: 5.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 358 QQGQYLLKHKRPAEAAEHFQ-------DPQWQGVA-------LYEAGNYAEAIKRFAQ----GSDAYSHYNRGNALAKAG 419
Cdd:COG2976    95 LLAKAAVDAGDLDKAAAQLQwvldnakDPALKALArlrlarvLLAQKKYDEALATLDAvkpeAFAALYAELRGDILLAQG 174

                          90       100
                  ....*....|....*....|.
gi 1119472667 420 EFEAALDAYEQALEAQPDLQP 440
Cdd:COG2976   175 DKAEARAAYQKALAALPEDAP 195
TPR_12 pfam13424
Tetratricopeptide repeat;
383-437 9.29e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 9.29e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1119472667 383 GVALYEAGNYAEAIKRFAQ---------GSD----AYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:pfam13424  10 AAVLRRLGRYDEALELLEKaleiarrllGPDhpltATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 333-453 1.34e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.52  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 333 LPLLLMGAPQPSYAFGLQDLWLRPDQQGQYLLkhkRPAEAAEHFQDPQWQGVALYEAGNYAEAIKRFAQGSDAYSHYNRG 412
Cdd:COG3914     9 LAALAAAALLAAAAAAELALAAELEAAALAAA---LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAA 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1119472667 413 NALAKAGEFEAALDAYEQALEAQPDLQPALKNKALVEALMQ 453
Cdd:COG3914    86 LLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALG 126
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 382-442 1.84e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.48  E-value: 1.84e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1119472667 382 QGVALYEAGNYAEAIKRFAQ-----GSDAYSHYNRGNALAKAGEFEAALDAYEQALEAQPDLQPAL 442
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEaleldPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEAL 79
TPR_8 pfam13181
Tetratricopeptide repeat;
405-437 1.88e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.84  E-value: 1.88e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119472667 405 AYSHYNRGNALAKAGEFEAALDAYEQALEAQPD 437
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 358-455 2.22e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.10  E-value: 2.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119472667 358 QQGQYLLKHKRPAEAAEHFQ-----DPQW------QGVALYEAGNYAEAIKRFAQG-----SDAYSHYNRGNALAKAGEF 421
Cdd:COG2956   149 ELAELYLEQGDYDEAIEALEkalklDPDCaralllLAELYLEQGDYEEAIAALERAleqdpDYLPALPRLAELYEKLGDP 228

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1119472667 422 EAALDAYEQALEAQPDLQPALknkALVEALMQEQ 455
Cdd:COG2956   229 EEALELLRKALELDPSDDLLL---ALADLLERKE 259
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH