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Conserved domains on  [gi|1092781827|ref|WP_070704237|]
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MULTISPECIES: LytR C-terminal domain-containing protein [Kytococcus]

Protein Classification

LytR C-terminal domain-containing protein( domain architecture ID 15997649)

LytR C-terminal domain-containing protein

CATH:  3.30.70.2390
PubMed:  21964069

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LytR_C super family cl16268
LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus ...
 139-245 2.83e-14

LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family


The actual alignment was detected with superfamily member NF035953:

Pssm-ID: 472888  Cd Length: 211  Bit Score: 69.55  E-value: 2.83e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827 139 SFEQLARQPAATPDQVRMNVFNTTSAVGRAGETAQAMRDRGFT-VDKVGNDPEkkwYPDD----TAIIRHGAASEPMART 213
Cdd:NF035953   66 SRDAMLDVAPAPLSDTKVRVLNASGQRGQAGEVADDLRDLGFApAPDAANDPV---YANQdlecQGQIRFGPAGRAAAAA 142

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1092781827 214 VAAQVPGARLSDDGRTDRTVDLVLGAKFETVN 245
Cdd:NF035953  143 VWLVAPCAELVRDGRTDDSVDLALGTYFTDLS 174
LytR_C pfam13399
LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus ...
 55-140 4.66e-09

LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family


:

Pssm-ID: 463868  Cd Length: 87  Bit Score: 52.40  E-value: 4.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827  55 VQVSVLNNGAGAGAAATAAREFEARGFTVLTTGNESDdaPRDATVVRYGPMGLTAARTVAQQIEGARMLRDERRNPS--- 131
Cdd:pfam13399   1 VRVAVLNGTGVPGLAARVADALRAAGFNVGEVGNAGN--ALEKTTIIYGAAAAAAARALAAALGGGEIVVDDVLVAStgd 78


                  ....*....
gi 1092781827 132 VDVVLGNSF 140
Cdd:pfam13399  79 VTVVLGKDF 87
 
Name Accession Description Interval E-value
integrity_Cei NF035953
envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding ...
 139-245 2.83e-14

envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding member Rv2700 from Mycobacterium tuberculosis, is a transmembrane protein with an extracellular LytR_C domain. It lacks any DNA-binding domain and is not a transcriptional regulator. It shares homology to C-terminal regions present in some members of the LytR-CpsA-Psr family, a family in which some characterized members transfer teichoic acids to from carriers to mature peptidoglycan.


Pssm-ID: 468277  Cd Length: 211  Bit Score: 69.55  E-value: 2.83e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827 139 SFEQLARQPAATPDQVRMNVFNTTSAVGRAGETAQAMRDRGFT-VDKVGNDPEkkwYPDD----TAIIRHGAASEPMART 213
Cdd:NF035953   66 SRDAMLDVAPAPLSDTKVRVLNASGQRGQAGEVADDLRDLGFApAPDAANDPV---YANQdlecQGQIRFGPAGRAAAAA 142

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1092781827 214 VAAQVPGARLSDDGRTDRTVDLVLGAKFETVN 245
Cdd:NF035953  143 VWLVAPCAELVRDGRTDDSVDLALGTYFTDLS 174
LytR_C pfam13399
LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus ...
 154-241 9.36e-12

LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family


Pssm-ID: 463868  Cd Length: 87  Bit Score: 59.72  E-value: 9.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827 154 VRMNVFNTTSAVGRAGETAQAMRDRGFTVDKVGNDPEkkwyPDDTAIIRHGAASEPMARTVAAQVPGARLSDDGRTDRT- 232
Cdd:pfam13399   1 VRVAVLNGTGVPGLAARVADALRAAGFNVGEVGNAGN----ALEKTTIIYGAAAAAAARALAAALGGGEIVVDDVLVASt 76

                          90
                  ....*....|.
gi 1092781827 233 --VDLVLGAKF 241
Cdd:pfam13399  77 gdVTVVLGKDF 87
LytR_C pfam13399
LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus ...
 55-140 4.66e-09

LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family


Pssm-ID: 463868  Cd Length: 87  Bit Score: 52.40  E-value: 4.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827  55 VQVSVLNNGAGAGAAATAAREFEARGFTVLTTGNESDdaPRDATVVRYGPMGLTAARTVAQQIEGARMLRDERRNPS--- 131
Cdd:pfam13399   1 VRVAVLNGTGVPGLAARVADALRAAGFNVGEVGNAGN--ALEKTTIIYGAAAAAAARALAAALGGGEIVVDDVLVAStgd 78


                  ....*....
gi 1092781827 132 VDVVLGNSF 140
Cdd:pfam13399  79 VTVVLGKDF 87
integrity_Cei NF035953
envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding ...
 53-150 7.72e-05

envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding member Rv2700 from Mycobacterium tuberculosis, is a transmembrane protein with an extracellular LytR_C domain. It lacks any DNA-binding domain and is not a transcriptional regulator. It shares homology to C-terminal regions present in some members of the LytR-CpsA-Psr family, a family in which some characterized members transfer teichoic acids to from carriers to mature peptidoglycan.


Pssm-ID: 468277  Cd Length: 211  Bit Score: 42.59  E-value: 7.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827  53 ATVQVSVLNNGAGAGAAATAAREFEARGFT-VLTTGNESDDAPRDATVV---RYGPMGLTAARTVAQQIEGARMLRDERR 128
Cdd:NF035953   79 SDTKVRVLNASGQRGQAGEVADDLRDLGFApAPDAANDPVYANQDLECQgqiRFGPAGRAAAAAVWLVAPCAELVRDGRT 158

                          90       100
                  ....*....|....*....|..
gi 1092781827 129 NPSVDVVLGNSFEQLARQPAAT 150
Cdd:NF035953  159 DDSVDLALGTYFTDLSPSQDAQ 180
 
Name Accession Description Interval E-value
integrity_Cei NF035953
envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding ...
 139-245 2.83e-14

envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding member Rv2700 from Mycobacterium tuberculosis, is a transmembrane protein with an extracellular LytR_C domain. It lacks any DNA-binding domain and is not a transcriptional regulator. It shares homology to C-terminal regions present in some members of the LytR-CpsA-Psr family, a family in which some characterized members transfer teichoic acids to from carriers to mature peptidoglycan.


Pssm-ID: 468277  Cd Length: 211  Bit Score: 69.55  E-value: 2.83e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827 139 SFEQLARQPAATPDQVRMNVFNTTSAVGRAGETAQAMRDRGFT-VDKVGNDPEkkwYPDD----TAIIRHGAASEPMART 213
Cdd:NF035953   66 SRDAMLDVAPAPLSDTKVRVLNASGQRGQAGEVADDLRDLGFApAPDAANDPV---YANQdlecQGQIRFGPAGRAAAAA 142

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1092781827 214 VAAQVPGARLSDDGRTDRTVDLVLGAKFETVN 245
Cdd:NF035953  143 VWLVAPCAELVRDGRTDDSVDLALGTYFTDLS 174
LytR_C pfam13399
LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus ...
 154-241 9.36e-12

LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family


Pssm-ID: 463868  Cd Length: 87  Bit Score: 59.72  E-value: 9.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827 154 VRMNVFNTTSAVGRAGETAQAMRDRGFTVDKVGNDPEkkwyPDDTAIIRHGAASEPMARTVAAQVPGARLSDDGRTDRT- 232
Cdd:pfam13399   1 VRVAVLNGTGVPGLAARVADALRAAGFNVGEVGNAGN----ALEKTTIIYGAAAAAAARALAAALGGGEIVVDDVLVASt 76

                          90
                  ....*....|.
gi 1092781827 233 --VDLVLGAKF 241
Cdd:pfam13399  77 gdVTVVLGKDF 87
LytR_C pfam13399
LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus ...
 55-140 4.66e-09

LytR cell envelope-related transcriptional attenuator; This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family


Pssm-ID: 463868  Cd Length: 87  Bit Score: 52.40  E-value: 4.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827  55 VQVSVLNNGAGAGAAATAAREFEARGFTVLTTGNESDdaPRDATVVRYGPMGLTAARTVAQQIEGARMLRDERRNPS--- 131
Cdd:pfam13399   1 VRVAVLNGTGVPGLAARVADALRAAGFNVGEVGNAGN--ALEKTTIIYGAAAAAAARALAAALGGGEIVVDDVLVAStgd 78


                  ....*....
gi 1092781827 132 VDVVLGNSF 140
Cdd:pfam13399  79 VTVVLGKDF 87
integrity_Cei NF035953
envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding ...
 53-150 7.72e-05

envelope integrity protein Cei; Cei (cell envelope integrity), as described for the founding member Rv2700 from Mycobacterium tuberculosis, is a transmembrane protein with an extracellular LytR_C domain. It lacks any DNA-binding domain and is not a transcriptional regulator. It shares homology to C-terminal regions present in some members of the LytR-CpsA-Psr family, a family in which some characterized members transfer teichoic acids to from carriers to mature peptidoglycan.


Pssm-ID: 468277  Cd Length: 211  Bit Score: 42.59  E-value: 7.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092781827  53 ATVQVSVLNNGAGAGAAATAAREFEARGFT-VLTTGNESDDAPRDATVV---RYGPMGLTAARTVAQQIEGARMLRDERR 128
Cdd:NF035953   79 SDTKVRVLNASGQRGQAGEVADDLRDLGFApAPDAANDPVYANQDLECQgqiRFGPAGRAAAAAVWLVAPCAELVRDGRT 158

                          90       100
                  ....*....|....*....|..
gi 1092781827 129 NPSVDVVLGNSFEQLARQPAAT 150
Cdd:NF035953  159 DDSVDLALGTYFTDLSPSQDAQ 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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