|
Name |
Accession |
Description |
Interval |
E-value |
| pheT_arch |
TIGR00471 |
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ... |
1-535 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273096 [Multi-domain] Cd Length: 551 Bit Score: 584.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 1 MAIITLPYRYLERLA-GTDRETLIDRIPMIGADIERIEEDH--VDVEFFPNRPDLYSPEGVARAMRGFLGIEEGLPVYTT 77
Cdd:TIGR00471 1 MPTVTVYKDDLEDLLiGTDRDEILEELPMMGDEIEGFDEESpeIKVEFNPNRPDLLSVEGLARSLRGYLGIEKGLKSYDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 78 RPSGITFSVDPGLADIRPYLDSAVIRNVSLDEEAIESLMGLQEALHWAVGRGRSKVAIGVHDLDKVTPPFHYIA-SPRSR 156
Cdd:TIGR00471 81 KKGDVKLTVDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRKVAIGIHDLDKVEFPFHYKAvSPNGI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 157 SFVPLDFEQEMTMEEILSDHPKGRDYAHLVEKFDKFPLIVDANDRVLSFPPIINGELTRVTTATKNILLDCTGTDRKAVM 236
Cdd:TIGR00471 161 KFVPLNSDQEMTPDEILEEHPKGIRYAHIIEDSDKFPLILDSKDDVLSMPPIINSELTKLTVNTRNLLIDVTGTDKTAVE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 237 TAVNIICTALAEAG-ATIETVTVAGEE----MPTLAPTERVVSVAECSRLLGIPLTPDEMARLLRRMRFEAEPDGDShVR 311
Cdd:TIGR00471 241 ITLNIACTMFADRGdGRITVVEVERPDehlgQPNLAPRFMEVSVEYINSLLGLNLSADEIAHSLKKMRLDAVQSDEK-LK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 312 VLIPCYRADILHDWDIFEDVAIAYGIENFDAALPATTTVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQ 391
Cdd:TIGR00471 320 VVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINTIGRLKPLNKVSDIIREIMVGLGFQEVIPLTLTSEEVNFKRMR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 392 REPAPgTLRVLHPISEEQTVVRTDLLPLLMETLQANKHRELPQRLFAVGDVV-------EDCVTFQKAAGVSIHPGADFS 464
Cdd:TIGR00471 400 IEDNN-DVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKIFEIGDVVvkddkseTRSRVVTKLAVGITHSEANFN 478
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1055289833 465 EAYAAVDVLCRELSLPYTVVESTDPAFIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDLKA 535
Cdd:TIGR00471 479 EIKSIVAALARELGIEYEIEESEHPSFIPGRGAKIVFEGKAIGHFGEIHPEVLTNFELEFPVSAFEVNIEV 549
|
|
| PLN02265 |
PLN02265 |
probable phenylalanyl-tRNA synthetase beta chain |
48-535 |
3.76e-100 |
|
probable phenylalanyl-tRNA synthetase beta chain
Pssm-ID: 215149 [Multi-domain] Cd Length: 597 Bit Score: 314.70 E-value: 3.76e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 48 NRPDLYSPEGVARAMRGFLGIEEgLPVYT----TRPSGITFSVDPGLADIRPYLDSAVIRNVSLDEEAIESLMGLQEALH 123
Cdd:PLN02265 74 NRYDLLCLEGLARALRVFLGTEP-IPTYRlaeiSKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 124 WAVGRGRSKVAIGVHDLDKVTPPFHYIA-SPRSRSFVPLDFEQEMTMEEIL----SDHpKGRDYAHLVEKFDKFPLIVDA 198
Cdd:PLN02265 153 QNICRRRTLVAIGTHDLDTLQGPFTYEAlPPEDINFVPLKQTKSFRADELMefykSDM-KLKKFLHIIENSPVFPVIYDS 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 199 NDRVLSFPPIINGELTRVTTATKNILLDCTGTD---RKAVMTAVNIICTALAEAGATIETVTVA---GEEM--PTLAPTE 270
Cdd:PLN02265 232 NRTVLSLPPIINGAHSAITLDTKNVFIECTATDltkAKIVLNTMVTMFSEYCARKFEVEPVEVVypdGKSTvyPDLSVRT 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 271 RVVSVAECSRLLGIPLTPDEMARLLRRMRFEAE--PDGDSHVRVLIPCYRADILHDWDIFEDVAIAYGIENFDAALPATT 348
Cdd:PLN02265 312 MEVDLSYINSSIGVSLDAEEVASLLNKMQLQAEqsSDDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSM 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 349 TVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQRePAPGTLRVL--HPISEEQTVVRTDLLPLLMETLQA 426
Cdd:PLN02265 392 TVGKQQPLNQFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNR-EDDGNSAVIigNPRSADFEVVRTSLLPGLLKTLGH 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 427 NKHRELPQRLFAVGDVV-----ED--CVTFQKAAGVSIHPGADFSEAYAAVDVLCRELSLP---------YTVVESTDPA 490
Cdd:PLN02265 471 NKDAPKPIKLFEVSDVVlldesKDvgARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPfveigdnngYYVEPSNEPE 550
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1055289833 491 FIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDLKA 535
Cdd:PLN02265 551 YFPGRQASIIYKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEP 595
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
194-543 |
3.53e-52 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 190.38 E-value: 3.53e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 194 LIVDANdRVLSFPPIINGELTRVTTATKNILLDC----------T----------------GTDRKAVMTAVNIICTALA 247
Cdd:COG0072 303 VIADDE-GPLALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTarrlglhsdasyrferGVDPALTVAALERATQLIL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 248 E-AGATI-ETVTVAGEEMPtlAPTERVVSVAECSRLLGIPLTPDEMARLLRRMRFEAEPDGDShVRVLIPCYRADILHDW 325
Cdd:COG0072 382 EiAGGEVgPGIVDVYPEPP--EPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDG-LTVTVPSWRFDIEIEA 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 326 DIFEDVAIAYGIENFDAALP-ATTTVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQREPApgtLRVLHP 404
Cdd:COG0072 459 DLIEEVARIYGYDNIPSTLPrAPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRREA---VRLANP 535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 405 ISEEQTVVRTDLLPLLMETLQANKHRELPQ-RLFAVGDV---VEDCVTFQK--AAGV---SIHPG--------ADFSEAY 467
Cdd:COG0072 536 ISEDLSVMRTSLLPGLLEAAAYNLNRGQKDvRLFEIGRVflpDEGEEPREPlhLAGVltgNREPEswggkarpVDFFDLK 615
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1055289833 468 AAVDVLCRELSLP-YTVVESTDPAFIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDLKAVPGYPAPP 543
Cdd:COG0072 616 GDVEALLAALGVPkLEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGPVYVFELDLDALLELARKV 692
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
344-533 |
9.65e-45 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 157.33 E-value: 9.65e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 344 LP-ATTTVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQREPAPGTLRVLHPISEEQTVVRTDLLPLLME 422
Cdd:pfam17759 5 LPkGPTTGGGLTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLLEDDPRRKAVKLANPLSEELSVMRTSLLPGLLE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 423 TLQANKHRELP-QRLFAVGDVVED--------------CVTFQKAAGVSIHPG---ADFSEAYAAVDVLCRELSLP-YTV 483
Cdd:pfam17759 85 TLAYNLNRGNPdVRLFEIGRVFLPdeleelpreprrlaGLLTGKRLPESWQGKarpVDFYDLKGIVEALLAALGIDdYEF 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1055289833 484 VESTDPAFIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDL 533
Cdd:pfam17759 165 EAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQPVYVFELDL 214
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
355-533 |
8.81e-43 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 151.26 E-value: 8.81e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 355 PITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMmqREPAPGTLRVLHPISEEQTVVRTDLLPLLMETLQANKHRE-LP 433
Cdd:cd00769 1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAELF--DGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnKP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 434 QRLFAVGDVV----EDCVTFQKAAGVSIHPG-----------ADFSEAYAAVDVLCREL--SLPYTVVESTDPAFIDGRR 496
Cdd:cd00769 79 LRLFEIGRVFlkdeDGPEEEEHLAALLSGNRepeswqgkgrpVDFYDAKGILEALLRALgiIVEFELEELDADLFHPGRS 158
|
170 180 190
....*....|....*....|....*....|....*..
gi 1055289833 497 GDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDL 533
Cdd:cd00769 159 AKIYVNGEVIGFIGELHPEVLKEFDLKEPVYAFELDL 195
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
94-251 |
1.63e-26 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 105.80 E-value: 1.63e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 94 RPYLDSAVIRNVSLdeeAIESLMGLQEALHWAVGRGRSkVAIGVHDLDKVTPPFHYIASPRSR---SFVPLDFEQEMTME 170
Cdd:smart00873 1 CPRYLGRVIRGVKN---TRPSPEWLQERLHRAGIRPIN-NVVDITNYVSLETGQPLHAFDLDKikgKDIPLRRAKEGEKF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 171 EILSDHPKGRDYAHLVEKFDKFPLI-----------VDANDRVLSFPPIINGELT-RVTTATKNILLDCT-----GTDRK 233
Cdd:smart00873 77 ETLDGKEYELDEGDLVIADDEGPLAlagvmggeeseVTENTTVIFLEPAIFSPRTiRITARTLNLFTDASgrferGVDPE 156
|
170
....*....|....*...
gi 1055289833 234 AVMTAVNIICTALAEAGA 251
Cdd:smart00873 157 LVELALDRAAALLLEICG 174
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pheT_arch |
TIGR00471 |
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ... |
1-535 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273096 [Multi-domain] Cd Length: 551 Bit Score: 584.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 1 MAIITLPYRYLERLA-GTDRETLIDRIPMIGADIERIEEDH--VDVEFFPNRPDLYSPEGVARAMRGFLGIEEGLPVYTT 77
Cdd:TIGR00471 1 MPTVTVYKDDLEDLLiGTDRDEILEELPMMGDEIEGFDEESpeIKVEFNPNRPDLLSVEGLARSLRGYLGIEKGLKSYDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 78 RPSGITFSVDPGLADIRPYLDSAVIRNVSLDEEAIESLMGLQEALHWAVGRGRSKVAIGVHDLDKVTPPFHYIA-SPRSR 156
Cdd:TIGR00471 81 KKGDVKLTVDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRKVAIGIHDLDKVEFPFHYKAvSPNGI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 157 SFVPLDFEQEMTMEEILSDHPKGRDYAHLVEKFDKFPLIVDANDRVLSFPPIINGELTRVTTATKNILLDCTGTDRKAVM 236
Cdd:TIGR00471 161 KFVPLNSDQEMTPDEILEEHPKGIRYAHIIEDSDKFPLILDSKDDVLSMPPIINSELTKLTVNTRNLLIDVTGTDKTAVE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 237 TAVNIICTALAEAG-ATIETVTVAGEE----MPTLAPTERVVSVAECSRLLGIPLTPDEMARLLRRMRFEAEPDGDShVR 311
Cdd:TIGR00471 241 ITLNIACTMFADRGdGRITVVEVERPDehlgQPNLAPRFMEVSVEYINSLLGLNLSADEIAHSLKKMRLDAVQSDEK-LK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 312 VLIPCYRADILHDWDIFEDVAIAYGIENFDAALPATTTVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQ 391
Cdd:TIGR00471 320 VVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINTIGRLKPLNKVSDIIREIMVGLGFQEVIPLTLTSEEVNFKRMR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 392 REPAPgTLRVLHPISEEQTVVRTDLLPLLMETLQANKHRELPQRLFAVGDVV-------EDCVTFQKAAGVSIHPGADFS 464
Cdd:TIGR00471 400 IEDNN-DVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKIFEIGDVVvkddkseTRSRVVTKLAVGITHSEANFN 478
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1055289833 465 EAYAAVDVLCRELSLPYTVVESTDPAFIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDLKA 535
Cdd:TIGR00471 479 EIKSIVAALARELGIEYEIEESEHPSFIPGRGAKIVFEGKAIGHFGEIHPEVLTNFELEFPVSAFEVNIEV 549
|
|
| PLN02265 |
PLN02265 |
probable phenylalanyl-tRNA synthetase beta chain |
48-535 |
3.76e-100 |
|
probable phenylalanyl-tRNA synthetase beta chain
Pssm-ID: 215149 [Multi-domain] Cd Length: 597 Bit Score: 314.70 E-value: 3.76e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 48 NRPDLYSPEGVARAMRGFLGIEEgLPVYT----TRPSGITFSVDPGLADIRPYLDSAVIRNVSLDEEAIESLMGLQEALH 123
Cdd:PLN02265 74 NRYDLLCLEGLARALRVFLGTEP-IPTYRlaeiSKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 124 WAVGRGRSKVAIGVHDLDKVTPPFHYIA-SPRSRSFVPLDFEQEMTMEEIL----SDHpKGRDYAHLVEKFDKFPLIVDA 198
Cdd:PLN02265 153 QNICRRRTLVAIGTHDLDTLQGPFTYEAlPPEDINFVPLKQTKSFRADELMefykSDM-KLKKFLHIIENSPVFPVIYDS 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 199 NDRVLSFPPIINGELTRVTTATKNILLDCTGTD---RKAVMTAVNIICTALAEAGATIETVTVA---GEEM--PTLAPTE 270
Cdd:PLN02265 232 NRTVLSLPPIINGAHSAITLDTKNVFIECTATDltkAKIVLNTMVTMFSEYCARKFEVEPVEVVypdGKSTvyPDLSVRT 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 271 RVVSVAECSRLLGIPLTPDEMARLLRRMRFEAE--PDGDSHVRVLIPCYRADILHDWDIFEDVAIAYGIENFDAALPATT 348
Cdd:PLN02265 312 MEVDLSYINSSIGVSLDAEEVASLLNKMQLQAEqsSDDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSM 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 349 TVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQRePAPGTLRVL--HPISEEQTVVRTDLLPLLMETLQA 426
Cdd:PLN02265 392 TVGKQQPLNQFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNR-EDDGNSAVIigNPRSADFEVVRTSLLPGLLKTLGH 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 427 NKHRELPQRLFAVGDVV-----ED--CVTFQKAAGVSIHPGADFSEAYAAVDVLCRELSLP---------YTVVESTDPA 490
Cdd:PLN02265 471 NKDAPKPIKLFEVSDVVlldesKDvgARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPfveigdnngYYVEPSNEPE 550
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1055289833 491 FIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDLKA 535
Cdd:PLN02265 551 YFPGRQASIIYKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEP 595
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
194-543 |
3.53e-52 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 190.38 E-value: 3.53e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 194 LIVDANdRVLSFPPIINGELTRVTTATKNILLDC----------T----------------GTDRKAVMTAVNIICTALA 247
Cdd:COG0072 303 VIADDE-GPLALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTarrlglhsdasyrferGVDPALTVAALERATQLIL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 248 E-AGATI-ETVTVAGEEMPtlAPTERVVSVAECSRLLGIPLTPDEMARLLRRMRFEAEPDGDShVRVLIPCYRADILHDW 325
Cdd:COG0072 382 EiAGGEVgPGIVDVYPEPP--EPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDG-LTVTVPSWRFDIEIEA 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 326 DIFEDVAIAYGIENFDAALP-ATTTVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQREPApgtLRVLHP 404
Cdd:COG0072 459 DLIEEVARIYGYDNIPSTLPrAPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRREA---VRLANP 535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 405 ISEEQTVVRTDLLPLLMETLQANKHRELPQ-RLFAVGDV---VEDCVTFQK--AAGV---SIHPG--------ADFSEAY 467
Cdd:COG0072 536 ISEDLSVMRTSLLPGLLEAAAYNLNRGQKDvRLFEIGRVflpDEGEEPREPlhLAGVltgNREPEswggkarpVDFFDLK 615
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1055289833 468 AAVDVLCRELSLP-YTVVESTDPAFIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDLKAVPGYPAPP 543
Cdd:COG0072 616 GDVEALLAALGVPkLEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGPVYVFELDLDALLELARKV 692
|
|
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
39-537 |
7.21e-52 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 189.23 E-value: 7.21e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 39 DHV-DVEFFPNRPDLYSPEGVARAMRGFLGIE----EGLPVYTTRPSGITFSV-DPGLAdirPYLDSAVIRNVSldeEAI 112
Cdd:PRK00629 154 DTViEISLTPNRADCLSVRGIARELAALLGLPlklpEIEPVPATIDDKLPVEIeDPDLC---PRYAGRVIKGVK---NIA 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 113 ESLMGLQEALhWAVGrGRSKVAI-----------G----VHDLDKVTPPFHyiasprsrsfVPLDFEQEmtmEEILSDhp 177
Cdd:PRK00629 228 PSPLWLQERL-RAAG-IRPINNVvditnyvmlelGqplhAFDLDKIGGGIV----------VRRAKEGE---KLTTLD-- 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 178 kGRDYahlveKFDKFPLIVDANDRVLSFPPIINGELTRVTTATKNILLDCT--------------------------GTD 231
Cdd:PRK00629 291 -GKER-----TLDPEDLVIADDKKPLALAGVMGGEDSEVTENTTNVLLESAyfdpvsirktarrlglrtdasyrferGVD 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 232 RKAVMTAVNIICTALAE-AGATIETVTVAGEEMPTLAPTErvVSVAECSRLLGIPLTPDEMARLLRRMRFEAEPDGDSHV 310
Cdd:PRK00629 365 PALTLLALERATALILElGGGEVVEGVVDVYPLPKEPTIT--LRLERINRLLGTEISDEEIVDILKRLGFEVTEVDGDGL 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 311 RVLIPCYRADILHDWDIFEDVAIAYGIENFDAALPATTTVAKEHPIT-AIERAVRSVMIGLGYLEVIPFTLSNERVLYSM 389
Cdd:PRK00629 443 TVTVPSWRFDIEIEEDLVEEVARIYGYDNIPSTPPVAALTMGGLTEAqRLLRRLRRALAALGYQEVITYSFVSPEDAKLF 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 390 MqrePAPGTLRVLHPISEEQTVVRTDLLPLLMETLQANKHRELPQ-RLFAVGDVVEDCVT----FQKAAGV--------- 455
Cdd:PRK00629 523 G---LNPEPLLLLNPISEELSVMRTSLLPGLLEAVAYNLNRGNKDvALFEIGRVFLPDGDlprePEHLAGVltgnrvees 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 456 -SIHPGADFSEAYAAVDVLCRELSLPYTVVESTD--PAFIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALD 532
Cdd:PRK00629 600 wGGKRPVDFFDLKGDVEALLEALGLPEVEFVAEFeaAALHPGRSAEIYLDGKVIGFIGELHPKVLKKLDLPGRTYVFELD 679
|
....*
gi 1055289833 533 LKAVP 537
Cdd:PRK00629 680 LDALL 684
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
344-533 |
9.65e-45 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 157.33 E-value: 9.65e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 344 LP-ATTTVAKEHPITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMMQREPAPGTLRVLHPISEEQTVVRTDLLPLLME 422
Cdd:pfam17759 5 LPkGPTTGGGLTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLLEDDPRRKAVKLANPLSEELSVMRTSLLPGLLE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 423 TLQANKHRELP-QRLFAVGDVVED--------------CVTFQKAAGVSIHPG---ADFSEAYAAVDVLCRELSLP-YTV 483
Cdd:pfam17759 85 TLAYNLNRGNPdVRLFEIGRVFLPdeleelpreprrlaGLLTGKRLPESWQGKarpVDFYDLKGIVEALLAALGIDdYEF 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1055289833 484 VESTDPAFIDGRRGDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDL 533
Cdd:pfam17759 165 EAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQPVYVFELDL 214
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
355-533 |
8.81e-43 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 151.26 E-value: 8.81e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 355 PITAIERAVRSVMIGLGYLEVIPFTLSNERVLYSMmqREPAPGTLRVLHPISEEQTVVRTDLLPLLMETLQANKHRE-LP 433
Cdd:cd00769 1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAELF--DGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnKP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 434 QRLFAVGDVV----EDCVTFQKAAGVSIHPG-----------ADFSEAYAAVDVLCREL--SLPYTVVESTDPAFIDGRR 496
Cdd:cd00769 79 LRLFEIGRVFlkdeDGPEEEEHLAALLSGNRepeswqgkgrpVDFYDAKGILEALLRALgiIVEFELEELDADLFHPGRS 158
|
170 180 190
....*....|....*....|....*....|....*..
gi 1055289833 497 GDIVVDGKIVGVFGEIHPAVLAAFDLEHSVAAFALDL 533
Cdd:cd00769 159 AKIYVNGEVIGFIGELHPEVLKEFDLKEPVYAFELDL 195
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
94-251 |
1.63e-26 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 105.80 E-value: 1.63e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 94 RPYLDSAVIRNVSLdeeAIESLMGLQEALHWAVGRGRSkVAIGVHDLDKVTPPFHYIASPRSR---SFVPLDFEQEMTME 170
Cdd:smart00873 1 CPRYLGRVIRGVKN---TRPSPEWLQERLHRAGIRPIN-NVVDITNYVSLETGQPLHAFDLDKikgKDIPLRRAKEGEKF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 171 EILSDHPKGRDYAHLVEKFDKFPLI-----------VDANDRVLSFPPIINGELT-RVTTATKNILLDCT-----GTDRK 233
Cdd:smart00873 77 ETLDGKEYELDEGDLVIADDEGPLAlagvmggeeseVTENTTVIFLEPAIFSPRTiRITARTLNLFTDASgrferGVDPE 156
|
170
....*....|....*...
gi 1055289833 234 AVMTAVNIICTALAEAGA 251
Cdd:smart00873 157 LVELALDRAAALLLEICG 174
|
|
| B5 |
pfam03484 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
273-336 |
8.65e-20 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 460942 [Multi-domain] Cd Length: 67 Bit Score: 83.21 E-value: 8.65e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1055289833 273 VSVAECSRLLGIPLTPDEMARLLRRMRFEAEPDGDSHVRVLIPCYRADILHDWDIFEDVAIAYG 336
Cdd:pfam03484 3 LRLDRINRLLGIDLSAEEIVEILERLGFEVEEEDGDTLTVTVPSYRPDILHEADLIEEVARIYG 66
|
|
| B5 |
smart00874 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
273-337 |
3.73e-19 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 197942 [Multi-domain] Cd Length: 68 Bit Score: 81.39 E-value: 3.73e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1055289833 273 VSVAECSRLLGIPLTPDEMARLLRRMRFEAEPDGDShVRVLIPCYRADILHDWDIFEDVAIAYGI 337
Cdd:smart00874 5 LRLERINRLLGLEILAEEIEEILKRLGFEVEVSGDT-LEVTVPSYRFDILIEADLIEEVARIYGY 68
|
|
| B3_4 |
pfam03483 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
93-235 |
2.52e-08 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 427327 [Multi-domain] Cd Length: 174 Bit Score: 53.71 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 93 IRPYLDSAVIRNVSLDEEAIESLmglQEALhWAVGrGRSK---------------VAIGVHDLDKVTPPfhyIASPRSRS 157
Cdd:pfam03483 1 ACPRYFGRVIRGVKKNRPSPEWL---QRRL-RRAG-IRPInnvvditnyvmlelgQPLHAFDLDKIAGD---IVVRLAKG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 158 ---FVPLDfEQEMTMEEilsdhpkgrdyahlvekfdKFPLIVDAnDRVLSFPPIINGELTRVTTATKNILLDCTGTDRKA 234
Cdd:pfam03483 73 gekFTTLD-GKERELDP-------------------GDLVIADD-DGPVALAGIMGGEESEVTEDTTNIFLESAGFDPVA 131
|
.
gi 1055289833 235 V 235
Cdd:pfam03483 132 I 132
|
|
| B3/B4 |
COG3382 |
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only] ... |
130-267 |
3.49e-05 |
|
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only];
Pssm-ID: 442609 [Multi-domain] Cd Length: 233 Bit Score: 45.23 E-value: 3.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 130 RSKVAIGVHDLDKVTPPFHYIASPRSRSFVPL-DFEQEMTMEEIlsdhpkgrdyahlvekfdkfPLIVDANDRVLSFPPI 208
Cdd:COG3382 111 RYLLPIGGYDLDKIEGDLRLRLARGGESFLPIgGDEEEPPEPGE--------------------VVYADDEGVFCRRWPW 170
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1055289833 209 INGELTRVTTATKNILL--DC-TGTDRKAVMTAVNIICTALAE-AGATIETVTVAGEEMPTLA 267
Cdd:COG3382 171 RDSERTKVTEETKNALFiiEGlPGVSAEDLEAALDELAELLERyLGGEVVKTRILDADNPEFE 233
|
|
| class_II_aaRS-like_core |
cd00768 |
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA ... |
355-545 |
1.70e-03 |
|
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. These enzymes are usually homodimers. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. The substrate specificity of this reaction is further determined by additional domains. Intererestingly, this domain is also found is asparagine synthase A (AsnA), in the accessory subunit of mitochondrial polymerase gamma and in the bacterial ATP phosphoribosyltransferase regulatory subunit HisZ.
Pssm-ID: 238391 [Multi-domain] Cd Length: 211 Bit Score: 40.18 E-value: 1.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 355 PITAIERAVRSVMIGLGYLEVipftlsnerVLYSMMQREPAPGT------LRVLHPISEEQTVVRTDLLPLLMETLqANK 428
Cdd:cd00768 1 IRSKIEQKLRRFMAELGFQEV---------ETPIVEREPLLEKAghepkdLLPVGAENEEDLYLRPTLEPGLVRLF-VSH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055289833 429 HRELPQRLFAVGDVVEDCVT----------FQKAAGVSIHPGADFS------EAYAAvdvLCREL--SLPYTVVESTDPA 490
Cdd:cd00768 71 IRKLPLRLAEIGPAFRNEGGrrglrrvrefTQLEGEVFGEDGEEASefeeliELTEE---LLRALgiKLDIVFVEKTPGE 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1055289833 491 FID---GRRGDIVVDGKiVGVFGEIHpaVLAAFDLEHSVAAFALDLKAVPGYPAPPGT 545
Cdd:cd00768 148 FSPggaGPGFEIEVDHP-EGRGLEIG--SGGYRQDEQARAADLYFLDEALEYRYPPTI 202
|
|
| |
