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Conserved domains on  [gi|1054624788|ref|WP_066392488|]
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MULTISPECIES: HPr family phosphocarrier protein [Fictibacillus]

Protein Classification

HPr family phosphocarrier protein( domain architecture ID 10788234)

HPr family phosphocarrier protein is part of a phosphoenolpyruvate-dependent phosphotransferase (PTS)-like system that catalyzes the phosphorylation of incoming substrates with their concomitant translocation across the cell membrane

CATH:  3.30.1340.10
Gene Ontology:  GO:0008982
PubMed:  12405346
SCOP:  4001693
TCDB:  8.A.8

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PtsH COG1925
HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport ...
 21-89 1.03e-11

HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport and metabolism];


:

Pssm-ID: 441528 [Multi-domain]  Cd Length: 88  Bit Score: 55.11  E-value: 1.03e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1054624788 21 FVNAAGSFESEILFFYQGIQINAK---GLLSVNLfflshysrNQNEPITLRIEGCDAQEAIKNLSLMLNGYL 89
Cdd:COG1925   22 LVQLASKFDSEITVEKGGKEVNAKsimGLMSLGA--------KKGDEVTITAEGPDAEEALDALAALIESGF 85
 
Name Accession Description Interval E-value
PtsH COG1925
HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport ...
 21-89 1.03e-11

HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport and metabolism];


Pssm-ID: 441528 [Multi-domain]  Cd Length: 88  Bit Score: 55.11  E-value: 1.03e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1054624788 21 FVNAAGSFESEILFFYQGIQINAK---GLLSVNLfflshysrNQNEPITLRIEGCDAQEAIKNLSLMLNGYL 89
Cdd:COG1925   22 LVQLASKFDSEITVEKGGKEVNAKsimGLMSLGA--------KKGDEVTITAEGPDAEEALDALAALIESGF 85
PTS-HPr pfam00381
PTS HPr component phosphorylation site;
20-86 3.35e-08

PTS HPr component phosphorylation site;


Pssm-ID: 459792 [Multi-domain]  Cd Length: 79  Bit Score: 46.22  E-value: 3.35e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054624788 20 EFVNAAGSFESEILFFYQGIQINAK---GLLSVNLfflshysrNQNEPITLRIEGCDAQEAIKNLSLMLN 86
Cdd:pfam00381 18 LLVQLASKFDSDITLEKGGKKVNAKsimGLMSLGA--------KQGDEITISAEGEDEEEALEALAALLE 79
PTS_HPr_family TIGR01003
Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains ...
 21-86 8.47e-07

Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS]


Pssm-ID: 273389 [Multi-domain]  Cd Length: 82  Bit Score: 42.64  E-value: 8.47e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1054624788 21 FVNAAGSFESEILFFYQGIQINAKGLLSVNLFFLShysrnQNEPITLRIEGCDAQEAIKNLSLMLN 86
Cdd:TIGR01003 22 LVKLASGFDSEITLTKNGKEVNAKSIMGIMMLGAG-----QGTEVTVSADGEDEAEALEALAKLFE 82
PRK13780 PRK13780
phosphocarrier protein HPr; Provisional
 22-82 2.13e-05

phosphocarrier protein HPr; Provisional


Pssm-ID: 237503 [Multi-domain]  Cd Length: 88  Bit Score: 39.30  E-value: 2.13e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1054624788 22 VNAAGSFESEILFFYQGIQINAK---GLLSVNLfflshysrNQNEPITLRIEGCDAQEAIKNLS 82
Cdd:PRK13780  23 VQTASKFDSDITLEYNGKSVNLKsimGVMSLGV--------GQGADITISAEGADAADAIAAIE 78
 
Name Accession Description Interval E-value
PtsH COG1925
HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport ...
 21-89 1.03e-11

HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport and metabolism];


Pssm-ID: 441528 [Multi-domain]  Cd Length: 88  Bit Score: 55.11  E-value: 1.03e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1054624788 21 FVNAAGSFESEILFFYQGIQINAK---GLLSVNLfflshysrNQNEPITLRIEGCDAQEAIKNLSLMLNGYL 89
Cdd:COG1925   22 LVQLASKFDSEITVEKGGKEVNAKsimGLMSLGA--------KKGDEVTITAEGPDAEEALDALAALIESGF 85
PTS-HPr pfam00381
PTS HPr component phosphorylation site;
20-86 3.35e-08

PTS HPr component phosphorylation site;


Pssm-ID: 459792 [Multi-domain]  Cd Length: 79  Bit Score: 46.22  E-value: 3.35e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054624788 20 EFVNAAGSFESEILFFYQGIQINAK---GLLSVNLfflshysrNQNEPITLRIEGCDAQEAIKNLSLMLN 86
Cdd:pfam00381 18 LLVQLASKFDSDITLEKGGKKVNAKsimGLMSLGA--------KQGDEITISAEGEDEEEALEALAALLE 79
PTS_HPr_family TIGR01003
Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains ...
 21-86 8.47e-07

Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS]


Pssm-ID: 273389 [Multi-domain]  Cd Length: 82  Bit Score: 42.64  E-value: 8.47e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1054624788 21 FVNAAGSFESEILFFYQGIQINAKGLLSVNLFFLShysrnQNEPITLRIEGCDAQEAIKNLSLMLN 86
Cdd:TIGR01003 22 LVKLASGFDSEITLTKNGKEVNAKSIMGIMMLGAG-----QGTEVTVSADGEDEAEALEALAKLFE 82
PRK13780 PRK13780
phosphocarrier protein HPr; Provisional
 22-82 2.13e-05

phosphocarrier protein HPr; Provisional


Pssm-ID: 237503 [Multi-domain]  Cd Length: 88  Bit Score: 39.30  E-value: 2.13e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1054624788 22 VNAAGSFESEILFFYQGIQINAK---GLLSVNLfflshysrNQNEPITLRIEGCDAQEAIKNLS 82
Cdd:PRK13780  23 VQTASKFDSDITLEYNGKSVNLKsimGVMSLGV--------GQGADITISAEGADAADAIAAIE 78
PRK10850 PRK10850
phosphocarrier protein Hpr;
4-81 3.55e-04

phosphocarrier protein Hpr;


Pssm-ID: 182777 [Multi-domain]  Cd Length: 85  Bit Score: 35.88  E-value: 3.55e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1054624788  4 ESVVLLPKRLSIGQINEFVNAAGSFESEILFFYQGIQINAKgllsvNLFFLSHYSRNQNEPITLRIEGCDAQEAIKNL 81
Cdd:PRK10850   5 EVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAK-----SLFKLQTLGLTQGTVVTISAEGEDEQKAVEHL 77
PRK13782 PRK13782
HPr family phosphocarrier protein;
21-82 3.65e-04

HPr family phosphocarrier protein;


Pssm-ID: 172320 [Multi-domain]  Cd Length: 82  Bit Score: 35.91  E-value: 3.65e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1054624788 21 FVNAAGSFESEILFFYQGIQINAKGLLSVNLFFLSHYSRnqnepITLRIEGCDAQEAIKNLS 82
Cdd:PRK13782  22 FVQEANRFHADIFIEKDGKKVNAKSIMGLMSLAIGTGSM-----ITIITEGSDEEEALEALA 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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