NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|968782155|ref|WP_058589195|]
View 

MULTISPECIES: tRNA1(Val) (adenine(37)-N6)-methyltransferase [Photorhabdus]

Protein Classification

tRNA1(Val) (adenine(37)-N6)-methyltransferase( domain architecture ID 11467886)

tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase is a class I SAM-dependent methyltransferase that specifically methylates the adenine in position 37 of tRNA(1)(Val)

CATH:  2.20.25.110
EC:  2.1.1.223
Gene Ontology:  GO:0016430|GO:1904047|GO:0008170|GO:0032259|GO:0008757
PubMed:  12826405|12504684
SCOP:  3000118

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 8-240 9.36e-97

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


:

Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 282.42  E-value: 9.36e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   8 RRDGFTFKQFFVGHDRCAMKVGTDGVLLGAWTPVSDKKAILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDN 87
Cdd:COG4123    2 RLDGFLFKQFRIIQPRCGYRFGTDAVLLAAFAPVKKGGRVLDLGTGTGVIALMLAQRS-PGARITGVEIQPEAAELARRN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  88 AEQSPWQRKIDVYQQDIGDFAEQY-SQCYDLIVSNPPYFEP--AVACRNEAREQARYTGSLTHQQLLQYAETLITADGLF 164
Cdd:COG4123   81 VALNGLEDRITVIHGDLKEFAAELpPGSFDLVVSNPPYFKAgsGRKSPDEARAIARHEDALTLEDLIRAAARLLKPGGRF 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 968782155 165 CVVLPYAIGEEFETMACHQGWFSHHRVNIRDRQGKPLHRMLLAFSRKEKTGLI--SELTIRQPDGAYTQEFQQLVTDF 240
Cdd:COG4123  161 ALIHPAERLAEILAALRKYGLGPKRLRPVHPRPGKPAKRVLLEARKGGRAGLRilPPLVIHDEDGEYTPEVKALLRDF 238
 
Name Accession Description Interval E-value
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 8-240 9.36e-97

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 282.42  E-value: 9.36e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   8 RRDGFTFKQFFVGHDRCAMKVGTDGVLLGAWTPVSDKKAILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDN 87
Cdd:COG4123    2 RLDGFLFKQFRIIQPRCGYRFGTDAVLLAAFAPVKKGGRVLDLGTGTGVIALMLAQRS-PGARITGVEIQPEAAELARRN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  88 AEQSPWQRKIDVYQQDIGDFAEQY-SQCYDLIVSNPPYFEP--AVACRNEAREQARYTGSLTHQQLLQYAETLITADGLF 164
Cdd:COG4123   81 VALNGLEDRITVIHGDLKEFAAELpPGSFDLVVSNPPYFKAgsGRKSPDEARAIARHEDALTLEDLIRAAARLLKPGGRF 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 968782155 165 CVVLPYAIGEEFETMACHQGWFSHHRVNIRDRQGKPLHRMLLAFSRKEKTGLI--SELTIRQPDGAYTQEFQQLVTDF 240
Cdd:COG4123  161 ALIHPAERLAEILAALRKYGLGPKRLRPVHPRPGKPAKRVLLEARKGGRAGLRilPPLVIHDEDGEYTPEVKALLRDF 238
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 47-130 5.52e-16

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 75.20  E-value: 5.52e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  47 ILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDNAEQSpWQRKIDVYQQDIgdFAEQYSQCYDLIVSNPPY-- 124
Cdd:PRK09328 112 VLDLGTGSGAIALALAKER-PDAEVTAVDISPEALAVARRNAKHG-LGARVEFLQGDW--FEPLPGGRFDLIVSNPPYip 187

                         90
                 ....*....|....*....
gi 968782155 125 -------------FEPAVA 130
Cdd:PRK09328 188 eadihllqpevrdHEPHLA 206
RF_mod_PrmC TIGR03534
protein-(glutamine-N5) methyltransferase, release factor-specific; Members of this protein ...
 41-130 3.55e-14

protein-(glutamine-N5) methyltransferase, release factor-specific; Members of this protein family are HemK (PrmC), a protein once thought to be involved in heme biosynthesis but now recognized to be a protein-glutamine methyltransferase that modifies the peptide chain release factors. All members of the seed alignment are encoded next to the release factor 1 gene (prfA) and confirmed by phylogenetic analysis. SIMBAL analysis (manuscript in prep.) shows the motif [LIV]PRx[DE]TE (in Escherichia coli, IPRPDTE) confers specificity for the release factors rather than for ribosomal protein L3. [Protein fate, Protein modification and repair]


Pssm-ID: 274634 [Multi-domain]  Cd Length: 250  Bit Score: 69.81  E-value: 3.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   41 VSDKKAILDIGCGSGLIALMLAQRtDENTKIDAVELDTEAALQAQDNAeqspwQR----KIDVYQqdiGDFAEQY-SQCY 115
Cdd:TIGR03534  84 LKKGPRVLDLGTGSGAIALALAKE-RPDARVTAVDISPEALAVARKNA-----RRlgleNVEFLQ---GDWFEPLpSGKF 154

                          90       100       110
                  ....*....|....*....|....*....|
gi 968782155  116 DLIVSNPPY---------------FEPAVA 130
Cdd:TIGR03534 155 DLIVSNPPYipeadihlldpevrdFEPRLA 184
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 40-178 1.63e-10

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 57.99  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   40 PVSDKKAILDIGCGSGLIALMLAQRTDENtKIDAVELDTEAALQAQDNAEqSPWQRKIDVYQQDIgdFAEQYSQCYDLIV 119
Cdd:pfam05175  28 PKDLSGKVLDLGCGAGVLGAALAKESPDA-ELTMVDINARALESARENLA-ANGLENGEVVASDV--YSGVEDGKFDLII 103

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 968782155  120 SNPPYfepavacrneaREQARYTGSLTHQQLLQYAETLITADGLFCVV---LPY--AIGEEFET 178
Cdd:pfam05175 104 SNPPF-----------HAGLATTYNVAQRFIADAKRHLRPGGELWIVAnrfLGYppLLEELFGN 156
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 47-125 2.20e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 53.59  E-value: 2.20e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 968782155  47 ILDIGCGSGLIALMLAQRTDEntKIDAVELDTEAALQAQDNAEQsPWQRKIDVYQQDIGDFAEQYSQCYDLIVSNPPYF 125
Cdd:cd02440    2 VLDLGCGTGALALALASGPGA--RVTGVDISPVALELARKAAAA-LLADNVEVLKGDAEELPPEADESFDVIISDPPLH 77
rADc smart00650
Ribosomal RNA adenine dimethylases;
47-124 6.82e-05

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 42.11  E-value: 6.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155    47 ILDIGCGSGLIALMLAQRTDentKIDAVELDTE--AALQaqdnaEQSPWQRKIDVYQQDIGDFAEQYSQcYDLIVSNPPY 124
Cdd:smart00650  17 VLEIGPGKGALTEELLERAK---RVTAIEIDPRlaPRLR-----EKFAAADNLTVIHGDALKFDLPKLQ-PYKVVGNLPY 87
 
Name Accession Description Interval E-value
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 8-240 9.36e-97

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 282.42  E-value: 9.36e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   8 RRDGFTFKQFFVGHDRCAMKVGTDGVLLGAWTPVSDKKAILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDN 87
Cdd:COG4123    2 RLDGFLFKQFRIIQPRCGYRFGTDAVLLAAFAPVKKGGRVLDLGTGTGVIALMLAQRS-PGARITGVEIQPEAAELARRN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  88 AEQSPWQRKIDVYQQDIGDFAEQY-SQCYDLIVSNPPYFEP--AVACRNEAREQARYTGSLTHQQLLQYAETLITADGLF 164
Cdd:COG4123   81 VALNGLEDRITVIHGDLKEFAAELpPGSFDLVVSNPPYFKAgsGRKSPDEARAIARHEDALTLEDLIRAAARLLKPGGRF 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 968782155 165 CVVLPYAIGEEFETMACHQGWFSHHRVNIRDRQGKPLHRMLLAFSRKEKTGLI--SELTIRQPDGAYTQEFQQLVTDF 240
Cdd:COG4123  161 ALIHPAERLAEILAALRKYGLGPKRLRPVHPRPGKPAKRVLLEARKGGRAGLRilPPLVIHDEDGEYTPEVKALLRDF 238
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 37-207 2.65e-17

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 78.65  E-value: 2.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  37 AWTPVSDKKAILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIGDfAEQYSQCYD 116
Cdd:COG2890  106 ALLPAGAPPRVLDLGTGSGAIALALAKER-PDARVTAVDISPDALAVARRNAERLGLEDRVRFLQGDLFE-PLPGDGRFD 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155 117 LIVSNPPY---------------FEPAVAcrneareqarytgsLT--------HQQLLQYAETLITADGLFCVVLPYAIG 173
Cdd:COG2890  184 LIVSNPPYipedeiallppevrdHEPRLA--------------LDggedgldfYRRIIAQAPRLLKPGGWLLLEIGEDQG 249

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 968782155 174 EEFETMACHQGWfshHRVNI-RDRQGKPlhRMLLA 207
Cdd:COG2890  250 EAVRALLEAAGF---ADVEThKDLAGRD--RVVVA 279
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 47-130 5.52e-16

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 75.20  E-value: 5.52e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  47 ILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDNAEQSpWQRKIDVYQQDIgdFAEQYSQCYDLIVSNPPY-- 124
Cdd:PRK09328 112 VLDLGTGSGAIALALAKER-PDAEVTAVDISPEALAVARRNAKHG-LGARVEFLQGDW--FEPLPGGRFDLIVSNPPYip 187

                         90
                 ....*....|....*....
gi 968782155 125 -------------FEPAVA 130
Cdd:PRK09328 188 eadihllqpevrdHEPHLA 206
RF_mod_PrmC TIGR03534
protein-(glutamine-N5) methyltransferase, release factor-specific; Members of this protein ...
 41-130 3.55e-14

protein-(glutamine-N5) methyltransferase, release factor-specific; Members of this protein family are HemK (PrmC), a protein once thought to be involved in heme biosynthesis but now recognized to be a protein-glutamine methyltransferase that modifies the peptide chain release factors. All members of the seed alignment are encoded next to the release factor 1 gene (prfA) and confirmed by phylogenetic analysis. SIMBAL analysis (manuscript in prep.) shows the motif [LIV]PRx[DE]TE (in Escherichia coli, IPRPDTE) confers specificity for the release factors rather than for ribosomal protein L3. [Protein fate, Protein modification and repair]


Pssm-ID: 274634 [Multi-domain]  Cd Length: 250  Bit Score: 69.81  E-value: 3.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   41 VSDKKAILDIGCGSGLIALMLAQRtDENTKIDAVELDTEAALQAQDNAeqspwQR----KIDVYQqdiGDFAEQY-SQCY 115
Cdd:TIGR03534  84 LKKGPRVLDLGTGSGAIALALAKE-RPDARVTAVDISPEALAVARKNA-----RRlgleNVEFLQ---GDWFEPLpSGKF 154

                          90       100       110
                  ....*....|....*....|....*....|
gi 968782155  116 DLIVSNPPY---------------FEPAVA 130
Cdd:TIGR03534 155 DLIVSNPPYipeadihlldpevrdFEPRLA 184
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 29-170 1.32e-13

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 67.14  E-value: 1.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  29 GTDgVLLGAWtPVSDKKAILDIGCGSGLIALMLAQRTDEnTKIDAVELDtEAALQ-AQDNAEQSPWQRkIDVYQQDigDF 107
Cdd:COG2813   37 GTR-LLLEHL-PEPLGGRVLDLGCGYGVIGLALAKRNPE-ARVTLVDVN-ARAVElARANAAANGLEN-VEVLWSD--GL 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 968782155 108 AEQYSQCYDLIVSNPPYfepavacrneaREQARYTGSLTHQQLLQYAETLiTADG-LFCVV---LPY 170
Cdd:COG2813  110 SGVPDGSFDLILSNPPF-----------HAGRAVDKEVAHALIADAARHL-RPGGeLWLVAnrhLPY 164
L3_gln_methyl TIGR03533
protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Members of this ...
 34-124 1.79e-12

protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Members of this protein family methylate ribosomal protein L3 on a glutamine side chain. This family is related to HemK, a protein-glutamine methyltranferase for peptide chain release factors. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274633 [Multi-domain]  Cd Length: 284  Bit Score: 65.23  E-value: 1.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   34 LLGAWTPvsdkKAILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIgdFAEQYSQ 113
Cdd:TIGR03533 116 WLEPEPV----KRILDLCTGSGCIAIACAYAF-PEAEVDAVDISPDALAVAEINIERHGLEDRVTLIQSDL--FAALPGR 188

                          90
                  ....*....|.
gi 968782155  114 CYDLIVSNPPY 124
Cdd:TIGR03533 189 KYDLIVSNPPY 199
hemK_fam TIGR00536
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme ...
 44-151 6.68e-12

HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme biosynthesis and originally suggested to be protoporphyrinogen oxidase. Functional analysis of the nearest homolog in Saccharomyces cerevisiae, YNL063w, finds it is not protoporphyrinogen oxidase and sequence analysis suggests that HemK homologs have S-adenosyl-methionine-dependent methyltransferase activity (Medline 99237242). Homologs are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both E. coli and H. influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain. [Protein fate, Protein modification and repair]


Pssm-ID: 273125 [Multi-domain]  Cd Length: 284  Bit Score: 63.53  E-value: 6.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   44 KKAILDIGCGSGLIALMLAQrTDENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIgdFAEQYSQCYDLIVSNPP 123
Cdd:TIGR00536 115 ILHILDLGTGSGCIALALAY-EFPNAEVIAVDISPDALAVAEENAEKNQLEHRVEFIQSNL--FEPLAGQKIDIIVSNPP 191

                          90       100
                  ....*....|....*....|....*...
gi 968782155  124 YFepavacrnEAREQARYTGSLTHQQLL 151
Cdd:TIGR00536 192 YI--------DEEDLADLPNVVRFEPLL 211
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 40-178 1.63e-10

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 57.99  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   40 PVSDKKAILDIGCGSGLIALMLAQRTDENtKIDAVELDTEAALQAQDNAEqSPWQRKIDVYQQDIgdFAEQYSQCYDLIV 119
Cdd:pfam05175  28 PKDLSGKVLDLGCGAGVLGAALAKESPDA-ELTMVDINARALESARENLA-ANGLENGEVVASDV--YSGVEDGKFDLII 103

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 968782155  120 SNPPYfepavacrneaREQARYTGSLTHQQLLQYAETLITADGLFCVV---LPY--AIGEEFET 178
Cdd:pfam05175 104 SNPPF-----------HAGLATTYNVAQRFIADAKRHLRPGGELWIVAnrfLGYppLLEELFGN 156
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 47-121 3.00e-10

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 55.65  E-value: 3.00e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 968782155   47 ILDIGCGSGLIALMLAQRTdeNTKIDAVELDTEAALQAQDNAEQSPWqrKIDVYQQDIGDFAEQySQCYDLIVSN 121
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRG--GARVTGVDLSPEMLERARERAAEAGL--NVEFVQGDAEDLPFP-DGSFDLVVSS 70
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 41-121 3.70e-10

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 56.18  E-value: 3.70e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  41 VSDKKAILDIGCGSGLIALMLAQRtdeNTKIDAVELDTEAALQAQDNAEqspwQRKIDVYQQDIGDFAEQYSQcYDLIVS 120
Cdd:COG2227   22 LPAGGRVLDVGCGTGRLALALARR---GADVTGVDISPEALEIARERAA----ELNVDFVQGDLEDLPLEDGS-FDLVIC 93


                 .
gi 968782155 121 N 121
Cdd:COG2227   94 S 94
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 47-120 1.14e-09

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 55.32  E-value: 1.14e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 968782155  47 ILDIGCGSGLIALMLAQRTDenTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIGDFAEQysQCYDLIVS 120
Cdd:COG2230   55 VLDIGCGWGGLALYLARRYG--VRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDLPAD--GQFDAIVS 124
PRK14968 PRK14968
putative methyltransferase; Provisional
 41-124 1.26e-09

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 56.06  E-value: 1.26e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  41 VSDKKAILDIGCGSGLIALMLAqrtDENTKIDAVELDTEAALQAQDNAEQSPW-QRKIDVYQQDIgdFAEQYSQCYDLIV 119
Cdd:PRK14968  21 DKKGDRVLEVGTGSGIVAIVAA---KNGKKVVGVDINPYAVECAKCNAKLNNIrNNGVEVIRSDL--FEPFRGDKFDVIL 95


                 ....*
gi 968782155 120 SNPPY 124
Cdd:PRK14968  96 FNPPY 100
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 47-125 2.20e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 53.59  E-value: 2.20e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 968782155  47 ILDIGCGSGLIALMLAQRTDEntKIDAVELDTEAALQAQDNAEQsPWQRKIDVYQQDIGDFAEQYSQCYDLIVSNPPYF 125
Cdd:cd02440    2 VLDLGCGTGALALALASGPGA--RVTGVDISPVALELARKAAAA-LLADNVEVLKGDAEELPPEADESFDVIISDPPLH 77
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
47-121 1.06e-08

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 51.36  E-value: 1.06e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 968782155  47 ILDIGCGSGLIALMLAQRTDENTkIDAVELDTEAALQAQDNAEQspwqrkIDVYQQDIGDFaeQYSQCYDLIVSN 121
Cdd:COG4106    5 VLDLGCGTGRLTALLAERFPGAR-VTGVDLSPEMLARARARLPN------VRFVVADLRDL--DPPEPFDLVVSN 70
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 47-121 1.52e-07

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 50.30  E-value: 1.52e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 968782155  47 ILDIGCGSGLIALMLAQRTdeNTKIDAVELDTEAALQAQDNAEQSPwQRKIDVYQQDIGDFAEQYSQCYDLIVSN 121
Cdd:COG0500   30 VLDLGCGTGRNLLALAARF--GGRVIGIDLSPEAIALARARAAKAG-LGNVEFLVADLAELDPLPAESFDLVVAF 101
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
47-121 1.60e-07

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 50.00  E-value: 1.60e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 968782155  47 ILDIGCGSGLIALMLAQRTDEntkIDAVELDTEAALQAQDNAEQspwqrkIDVYQQDIGDFAEQYSQcYDLIVSN 121
Cdd:COG4976   50 VLDLGCGTGLLGEALRPRGYR---LTGVDLSEEMLAKAREKGVY------DRLLVADLADLAEPDGR-FDLIVAA 114
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 37-123 1.82e-07

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 50.95  E-value: 1.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  37 AWTPVSDKKAILDIGCGSGLIALMLAQRTdenTKIDAVELDTEAALQAQDNAEQSPWQRkIDVYQQDIGDFAEQYSQC-- 114
Cdd:COG2265  227 EWLDLTGGERVLDLYCGVGTFALPLARRA---KKVIGVEIVPEAVEDARENARLNGLKN-VEFVAGDLEEVLPELLWGgr 302


                 ....*....
gi 968782155 115 YDLIVSNPP 123
Cdd:COG2265  303 PDVVVLDPP 311
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 42-121 1.88e-07

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 49.34  E-value: 1.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   42 SDKKAILDIGCGSGLIALMLAQRTDENTKIDAVELDTEAALQAQDNAEQSPWQRkIDVYQQDIGDFAEQYS-QCYDLIVS 120
Cdd:pfam13847   2 DKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENAQKLGFDN-VEFEQGDIEELPELLEdDKFDVVIS 80


                  .
gi 968782155  121 N 121
Cdd:pfam13847  81 N 81
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
45-121 5.28e-07

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 49.40  E-value: 5.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  45 KAILDIGCGSG---LIALMLAQRtdentKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQqdiGDFAEQysQCYDLIVSN 121
Cdd:COG2264  150 KTVLDVGCGSGilaIAAAKLGAK-----RVLAVDIDPVAVEAARENAELNGVEDRIEVVL---GDLLED--GPYDLVVAN 219
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 37-121 7.16e-07

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 47.30  E-value: 7.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  37 AWTPVSDKKAILDIGCGSGLIALMLAQRtdeNTKIDAVELDTEAALQAQDNAEQSPWQrkIDVYQQDIGD--FAEQYsqc 114
Cdd:COG2226   16 AALGLRPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERAAEAGLN--VEFVVGDAEDlpFPDGS--- 87


                 ....*..
gi 968782155 115 YDLIVSN 121
Cdd:COG2226   88 FDLVISS 94
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
45-121 1.55e-06

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 47.84  E-value: 1.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  45 KAILDIGCGSG---LIALMLAqrtdeNTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIGdfaeqysqcYDLIVSN 121
Cdd:PRK00517 121 KTVLDVGCGSGilaIAAAKLG-----AKKVLAVDIDPQAVEAARENAELNGVELNVYLPQGDLK---------ADVIVAN 186
UPF0020 pfam01170
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated ...
 33-124 1.73e-06

Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.


Pssm-ID: 395932 [Multi-domain]  Cd Length: 184  Bit Score: 46.96  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   33 VLLGAWTPVSdkkAILDIGCGSGLI----ALMLAQR------TDENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQ 102
Cdd:pfam01170  21 VNLAGWKPGD---PLLDPMCGSGTIlieaALMGANIapgkfdARVRAPLYGSDIDRRMVQGARLNAENAGVGDLIEFVQA 97

                          90       100
                  ....*....|....*....|..
gi 968782155  103 DIGDFAEQYSQcYDLIVSNPPY 124
Cdd:pfam01170  98 DAADLPLLEGS-VDVIVTNPPY 118
Methyltransf_3 pfam01596
O-methyltransferase; Members of this family are O-methyltransferases. The family includes ...
 26-125 4.27e-06

O-methyltransferase; Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.


Pssm-ID: 396257 [Multi-domain]  Cd Length: 203  Bit Score: 45.95  E-value: 4.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   26 MKVGTD-GVLLGAWTPVSDKKAILDIGCGSGLIALMLAQRTDENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDI 104
Cdd:pfam01596  25 MQVSPDeGQFLGMLVKLTGAKNVLEIGVFTGYSALAMALALPEDGKITAIDIDPEAYEIAKKFIQKAGVAHKISFILGPA 104

                          90       100       110
                  ....*....|....*....|....*....|.
gi 968782155  105 GDFAEQYSQ-----CYDLIV-----SNPPYF 125
Cdd:pfam01596 105 LKVLEQLTQdkplpEFDFIFidadkSNYPNY 135
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
45-123 5.36e-06

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 45.67  E-value: 5.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  45 KAILDIGCGSGLIA----LMLAQRtdentkIDAVELDTEAALQAQDNAEQSPwqRKIDVYQQDIGDFAEQYSqcYDLIVS 120
Cdd:COG2263   47 KTVLDLGCGTGMLAigaaLLGAKK------VVGVDIDPEALEIARENAERLG--VRVDFIRADVTRIPLGGS--VDTVVM 116


                 ...
gi 968782155 121 NPP 123
Cdd:COG2263  117 NPP 119
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
41-103 6.17e-06

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 45.80  E-value: 6.17e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 968782155  41 VSDKKAILDIGCGSGLIALMLAQRtdENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQD 103
Cdd:COG4076   33 VKPGDVVLDIGTGSGLLSMLAARA--GAKKVYAVEVNPDIAAVARRIIAANGLSDRITVINAD 93
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 39-203 6.26e-05

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 42.24  E-value: 6.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  39 TPVSDKKAILDIGCGSG--LI-ALMLaqrtdeNTKIDAVELDTEAALQAQDNAEqspW--QRKIDVYQQDIGDFAEQySQ 113
Cdd:COG1041   22 AGAKEGDTVLDPFCGTGtiLIeAGLL------GRRVIGSDIDPKMVEGARENLE---HygYEDADVIRGDARDLPLA-DE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155 114 CYDLIVSNPPYfepavacrneareqARYTGSLTHQQLLQYAETL-----ITADGLFCVVlpyAIGEEFETMACHQGWfsh 188
Cdd:COG1041   92 SVDAIVTDPPY--------------GRSSKISGEELLELYEKALeeaarVLKPGGRVVI---VTPRDIDELLEEAGF--- 151

                        170
                 ....*....|....*
gi 968782155 189 hrvNIRDRQGKPLHR 203
Cdd:COG1041  152 ---KVLERHEQRVHK 163
rADc smart00650
Ribosomal RNA adenine dimethylases;
47-124 6.82e-05

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 42.11  E-value: 6.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155    47 ILDIGCGSGLIALMLAQRTDentKIDAVELDTE--AALQaqdnaEQSPWQRKIDVYQQDIGDFAEQYSQcYDLIVSNPPY 124
Cdd:smart00650  17 VLEIGPGKGALTEELLERAK---RVTAIEIDPRlaPRLR-----EKFAAADNLTVIHGDALKFDLPKLQ-PYKVVGNLPY 87
Nnt1 COG3897
Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, ...
 41-119 7.14e-05

Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443104 [Multi-domain]  Cd Length: 216  Bit Score: 42.56  E-value: 7.14e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 968782155  41 VSDKKaILDIGCGSGLIALMLAQRtdENTKIDAVELDTEAALQAQDNAEQSpwQRKIDVYQQDIGDFAEqySQCYDLIV 119
Cdd:COG3897   69 VAGKR-VLELGCGLGLVGIAAAKA--GAADVTATDYDPEALAALRLNAALN--GVAITTRLGDWRDPPA--AGGFDLIL 140
PRK01544 PRK01544
bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) ...
 47-124 1.14e-04

bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase; Reviewed


Pssm-ID: 234958 [Multi-domain]  Cd Length: 506  Bit Score: 42.93  E-value: 1.14e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 968782155  47 ILDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIgdFAEQYSQCYDLIVSNPPY 124
Cdd:PRK01544 142 ILELGTGSGCIAISLLCEL-PNANVIATDISLDAIEVAKSNAIKYEVTDRIQIIHSNW--FENIEKQKFDFIVSNPPY 216
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 48-121 1.25e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 40.04  E-value: 1.25e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 968782155   48 LDIGCGSGLIALMLAQRTdENTKIDAVELDTEAALQAQDNAEQSPwQRKIDVYQQDIGDFAEQYSQCYDLIVSN 121
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAL-PGLEYTGLDISPAALEAARERLAALG-LLNAVRVELFQLDLGELDPGSFDVVVAS 72
YtxK COG0827
Adenine-specific DNA N6-methylase [Replication, recombination and repair];
47-124 1.69e-04

Adenine-specific DNA N6-methylase [Replication, recombination and repair];


Pssm-ID: 440589 [Multi-domain]  Cd Length: 327  Bit Score: 41.86  E-value: 1.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  47 ILDIGCGSGLIALMLAQRTDENTKIDAVELDteaALQAQDNAEQSPWQRK-IDVYQQDigdfAEQYSQC--YDLIVSNPP 123
Cdd:COG0827  119 ILDPAVGTGNLLTTVLNQLKKKVNAYGVEVD---DLLIRLAAVLANLQGHpVELFHQD----ALQPLLIdpVDVVISDLP 191


                 .
gi 968782155 124 Y 124
Cdd:COG0827  192 V 192
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 45-121 1.87e-04

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 41.87  E-value: 1.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155   45 KAILDIGCGSGLI---ALML-AQrtdentKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQdigdfAEQYSQCYDLIVS 120
Cdd:pfam06325 163 ESVLDVGCGSGILaiaALKLgAK------KVVGVDIDPVAVRAAKENAELNGVEARLEVYLP-----GDLPKEKADVVVA 231


                  .
gi 968782155  121 N 121
Cdd:pfam06325 232 N 232
SpeE COG0421
Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];
45-120 4.01e-04

Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];


Pssm-ID: 440190 [Multi-domain]  Cd Length: 195  Bit Score: 40.20  E-value: 4.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  45 KAILDIGCGSGLIALMLAqRTDENTKIDAVELD---TEAA---LQAQDNAEQSPwqrKIDVYQQDIGDFAEQYSQCYDLI 118
Cdd:COG0421   39 KRVLIIGGGDGGLARELL-KHPPVERVDVVEIDpevVELAreyFPLLAPAFDDP---RLRVVIGDGRAFLREAEESYDVI 114


                 ..
gi 968782155 119 VS 120
Cdd:COG0421  115 IV 116
PRK14967 PRK14967
putative methyltransferase; Provisional
 47-124 6.46e-04

putative methyltransferase; Provisional


Pssm-ID: 184931 [Multi-domain]  Cd Length: 223  Bit Score: 39.65  E-value: 6.46e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 968782155  47 ILDIGCGSGLIALMLAQRTDEntKIDAVELDTEAALQAQDNAEQSpwQRKIDVYQqdiGDFAEQYS-QCYDLIVSNPPY 124
Cdd:PRK14967  40 VLDLCTGSGALAVAAAAAGAG--SVTAVDISRRAVRSARLNALLA--GVDVDVRR---GDWARAVEfRPFDVVVSNPPY 111
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 48-121 6.46e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 38.03  E-value: 6.46e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 968782155   48 LDIGCGSGLIALMLAQRTDEntkIDAVELDTEAALQAQDNAEqspwQRKIDVYQQDIGD--FAEQYsqcYDLIVSN 121
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGAR---VTGVDISPEMLELAREKAP----REGLTFVVGDAEDlpFPDNS---FDLVLSS 66
CMAS pfam02353
Mycolic acid cyclopropane synthetase; This family consist of ...
 47-120 9.80e-04

Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.


Pssm-ID: 396777 [Multi-domain]  Cd Length: 272  Bit Score: 39.62  E-value: 9.80e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 968782155   47 ILDIGCGSGLIALMLAQRTDENtkIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIGDFAEQysqcYDLIVS 120
Cdd:pfam02353  65 LLDIGCGWGGLMRRAAERYDVN--VVGLTLSKNQYKLARKRVAAEGLARKVEVLLQDYRDFDEP----FDRIVS 132
RlmL COG0116
23S rRNA G2445 N2-methylase RlmL [Translation, ribosomal structure and biogenesis]; 23S rRNA ...
 62-124 3.20e-03

23S rRNA G2445 N2-methylase RlmL [Translation, ribosomal structure and biogenesis]; 23S rRNA G2445 N2-methylase RlmL is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 439886 [Multi-domain]  Cd Length: 369  Bit Score: 38.16  E-value: 3.20e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 968782155  62 AQRTDENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIGDFAEQYSqcYDLIVSNPPY 124
Cdd:COG0116  244 RIKRDPPLPIFGSDIDPRAIEAARENAERAGVADLIEFEQADFRDLEPPAE--PGLIITNPPY 304
PRK12335 PRK12335
tellurite resistance protein TehB; Provisional
 47-120 3.39e-03

tellurite resistance protein TehB; Provisional


Pssm-ID: 183450 [Multi-domain]  Cd Length: 287  Bit Score: 38.00  E-value: 3.39e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 968782155  47 ILDIGCGSGLIALMLAQRTDENTKIDAveldTEAALQA-QDNAEQSpwQRKIDVYQQDIGDFAEQysQCYDLIVS 120
Cdd:PRK12335 124 ALDLGCGQGRNSLYLALLGFDVTAVDI----NQQSLENlQEIAEKE--NLNIRTGLYDINSASIQ--EEYDFILS 190
speE PRK01581
polyamine aminopropyltransferase;
41-164 4.19e-03

polyamine aminopropyltransferase;


Pssm-ID: 234961 [Multi-domain]  Cd Length: 374  Bit Score: 38.02  E-value: 4.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 968782155  41 VSDKKAILDIGCGSGLiALMLAQRTDENTKIDAVELDtEAALQAQDNAEQ-------SPWQRKIDVYQQDIGDFAEQYSQ 113
Cdd:PRK01581 148 VIDPKRVLILGGGDGL-ALREVLKYETVLHVDLVDLD-GSMINMARNVPElvslnksAFFDNRVNVHVCDAKEFLSSPSS 225

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 968782155 114 CYDLIVSNPPyfEPAvacrneareqARYTGSLTHQQLLQYAETLITADGLF 164
Cdd:PRK01581 226 LYDVIIIDFP--DPA----------TELLSTLYTSELFARIATFLTEDGAF 264
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH