|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
1-435 |
5.33e-140 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 407.68 E-value: 5.33e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 1 MYTNKEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDV 80
Cdd:cd13133 1 PGGYREILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVALAASGPAGVLYFAILMLFFGLSSGVQVFVAQYNGAGRYSRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 81 GPVMIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNA 160
Cdd:cd13133 81 GRVLWQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMVAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 161 VVMALVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWQKIDFSLLGKILSISCFT 240
Cdd:cd13133 161 LVMVVVNIVLDYALIFGKLGFPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRRRFGLRRAWRFDRELLRRILRLGLPS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 241 MIQYFLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLI 320
Cdd:cd13133 241 GLQFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALAY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 321 MVVCVAVVVLFPHAMLSVYTNEP---ALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYI 397
Cdd:cd13133 321 MLLLGILFLLFPELLLSIFTPGAdfaLIAELAVPLLRFVAAYILFDALALVFAGALRGAGDTRFVMLAELIVAWLYLLPP 400
|
410 420 430
....*....|....*....|....*....|....*...
gi 949782817 398 LWIGMVVKAPVSVCFSIEVVYYSLLLLSSIIYLKKAKW 435
Cdd:cd13133 401 AYLLVVLGAGLAGAWTVETVYVIVLALIFLLRFRSGKW 438
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
3-401 |
1.25e-66 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 218.86 E-value: 1.25e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 3 TNKEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGP 82
Cdd:COG0534 6 ILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDREEARR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 83 VMIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVV 162
Cdd:COG0534 86 VLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 163 MALVNVLLDYILIFGkfgmPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSISCFTMI 242
Cdd:COG0534 166 GNVLNIVLDPLLIFG----GGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLRDL-RPDRKILKRILRIGLPAGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 243 QYFLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMV 322
Cdd:COG0534 241 QQLAESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGIGL 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949782817 323 VCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYILWIG 401
Cdd:COG0534 321 LLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAYLL 399
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
5-404 |
7.77e-50 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 174.62 E-value: 7.77e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVM 84
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 85 IQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMA 164
Cdd:cd13137 81 GQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 165 LVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSISCFTMIQY 244
Cdd:cd13137 161 VLNIVLDYVLIFGLWGFPGLGVAGAALATVISRVVGALLLLFLLLRGRLPIKISFKGF-RLDRKIIKKLLRIGLPAGLEQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 245 FLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVC 324
Cdd:cd13137 240 LLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMGLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 325 VAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYILWIGMVV 404
Cdd:cd13137 320 GLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLISMWLVRLPLAYLLGFV 399
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
5-385 |
4.13e-42 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 154.19 E-value: 4.13e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVM 84
Cdd:cd13131 3 RALLRLALPILIAQLAQMAMGFVDTVMAGRLGADDLAAVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIRRAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 85 IQGGTFLLGLAMLMFGLTHLLAPsIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMA 164
Cdd:cd13131 83 RQGLWLALLLSLPLMLLLWLAPP-ILPLMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITLLAL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 165 LVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLN-HWQKIDFSLLGKILSISCFTMIQ 243
Cdd:cd13131 162 VLNIPLNYVLIFGKFGLPALGGAGAGLATAIVYWLMFLALAFYIRRHKRFRRYRLFaRFWRPDWARLKELLRLGLPIGLT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 244 YFLAMATWFVFFIAIERLGQRELAIANIVRSI-YIVMLIPvQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMV 322
Cdd:cd13131 242 IFFEVSLFAAVALLMGRLGTTVLAAHQIALNFaSLLFMVP-LGISMAATVRVGFALGAGDPADARRAGLVGLGLGVGFAA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949782817 323 VCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALIL 385
Cdd:cd13131 321 LTALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYKDTRVPFLL 383
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
13-346 |
6.79e-41 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 148.55 E-value: 6.79e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 13 PIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGTFLL 92
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 93 GLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVNVLLDY 172
Cdd:TIGR00797 81 LLGLPVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILNY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 173 ILIFGKFGMpeMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGlNHWQKIDFSLLGKILSISCFTMIQYFLAMATWF 252
Cdd:TIGR00797 161 ILIFGKFGF--LGIVGAALATVISYWLMFLLLLYYIKKAKKIGLKW-EGLLKPDWEVLKRLLKLGLPIAFRVILESLSFA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 253 VFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVCVAVVVLFP 332
Cdd:TIGR00797 238 LLALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFR 317
|
330
....*....|....
gi 949782817 333 HAMLSVYTNEPALL 346
Cdd:TIGR00797 318 EFIARLFTNDPEVL 331
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
3-395 |
1.36e-37 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 141.87 E-value: 1.36e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 3 TNKEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGP 82
Cdd:cd13134 1 FKLSLFALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 83 VMIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVV 162
Cdd:cd13134 81 IAGVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 163 MALVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFkKFGLNHWQKIDFSLLGKILSISCFTMI 242
Cdd:cd13134 161 MNILNIVGNYLLIFGWFGLPKLGVAGVAISTVISRAVGLVLLFILLFRKLKI-RFRLKDLRPFPKKLLKKILKIGLPSAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 243 QYFLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMV 322
Cdd:cd13134 240 EELSYNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVSL 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949782817 323 VCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYAL 395
Cdd:cd13134 320 AVALLLALFREPILGLFTDDPEIIALGKTLLLISILLEPGRAFNIVLIGSLRAAGDARFPVLIGIISMWGISV 392
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
5-403 |
2.16e-36 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 138.58 E-value: 2.16e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVM 84
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVGNVTTPFNTITGFLGSISIGFTILGSQSVGAKDIKRINDYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 85 IQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMA 164
Cdd:cd13135 81 ISSIVYNSIIGVILFLLWLFGARIIFVLFGVDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETKPIMYGGIIKN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 165 LVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIY--TYAKVDFKKFGLNHwQKIDFSLLGKILSISCFTMI 242
Cdd:cd13135 161 LLNVILDYVLIFGNFGFPRLGIIGAAIATTIANVLNLIILVYLcrKIKKLTFKLSNTKV-LKANIRPYKFTIKLGLPLGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 243 QYFLamatWFVFFIAIER----LGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSF 318
Cdd:cd13135 240 EEFL----WNIGNLAVIRilnrIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLGLGL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 319 LIMVVCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILE-MGTLVFYALYI 397
Cdd:cd13135 316 LIYIAAAIVFLAFPYKILSLFTNDPELINYSIPYLIFIIIILFFKSINIVYGFAIRAIGDTKWMLYTQiIGTIIVVSVAL 395
|
....*.
gi 949782817 398 LWIGMV 403
Cdd:cd13135 396 LLIFVF 401
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
13-404 |
6.23e-35 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 134.37 E-value: 6.23e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 13 PIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGTFLL 92
Cdd:cd12082 3 PLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVLAI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 93 GLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVNVLLDY 172
Cdd:cd12082 83 LLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNILLDP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 173 ILIFGKFGmPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSISCFTMIQYFLAMATWF 252
Cdd:cd12082 163 LLIFGLGP-PELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLL-KPDLELLRRLLRIGLPSAIQNSLLSLGLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 253 VF-FIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVCVAVVVLF 331
Cdd:cd12082 241 IIvAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLILLF 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949782817 332 PHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYILWIGMVV 404
Cdd:cd12082 321 PEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLPLAYVLAYL 393
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
11-400 |
1.59e-34 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 133.35 E-value: 1.59e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 11 SYPIFLGLLAQNIINVTDTAFLGR-VGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGT 89
Cdd:cd13138 9 ALPLLLSNLLQQLYNLVDLLIVGQfLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAKKAVGTLLV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 90 FLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKvLTMNAVVMALV-NV 168
Cdd:cd13138 89 LFLILGIVLTILGLLFAPPILRLMNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSK-TPLYFVIIACVlNI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 169 LLDYILIFGkfgmPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSISCFTMIQYFLAM 248
Cdd:cd13138 168 ILDLLFIAV----FHMGVAGAALATVIAQAISVLLALYYLRKKKLPFKLSLKDF-RFDKEILKEILKIGLPSALQQSLVS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 249 ATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVCVAVV 328
Cdd:cd13138 243 ISFLIINSIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLIIILLV 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949782817 329 VLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYILWI 400
Cdd:cd13138 323 FFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWLVRIPLAYL 394
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
7-373 |
1.72e-30 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 121.85 E-value: 1.72e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 7 IWNVSYPIFLGLLAQNIINVTDTAFLGR-VGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMI 85
Cdd:cd13143 6 FLKFALPAIIGMLVNGLYNIVDGIFVGHgVGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKANRIFS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 86 QGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMAL 165
Cdd:cd13143 86 TALLLSLILGLLLTILGLLFLDPLLRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGMLIGAV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 166 VNVLLDYILIFGkfgmPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSI--SCFTMiQ 243
Cdd:cd13143 166 LNIILDPLFIFV----LGLGIAGAALATVIAQLISLLLLLLYFFRGKSLLKLSLLRF-KLSLKIIKEILALgfPSFLM-Q 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 244 YFLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVV 323
Cdd:cd13143 240 LSSSVVTIVLNLTLLGYGGDIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIYGLV 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 949782817 324 CVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIAS---VANIYFNAI 373
Cdd:cd13143 320 LFLILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGiniVLSGYFQAI 372
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-404 |
6.59e-30 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 120.76 E-value: 6.59e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 11 SYPIFLGLLAQNIINVTDTAFLGRVGEVELGA-SAMGGLFYIcVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGT 89
Cdd:cd13142 17 AWPIIVSNLLQVAYNLADTFWLGRLGADAVAApSISWPLIFL-FISLGGGLTVAGTALVAQYTGAGDYDKANKVAGQTFS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 90 FLLGLAMLMFGLTHLLAPSIVRLLIS-SDSIFDATMEFLNWRIWGFFFAFVNVMFRALY--IGITRTKVLTMnaVVMALV 166
Cdd:cd13142 96 FVIILSLILAVLGYILSRPLLLLLIGaPEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLrgIGDTKTPMKIM--FGSVLL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 167 NVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSISCFTMIQYfL 246
Cdd:cd13142 174 NVILDPLLIFGIGPFPGLGVAGAALATVISRGIAAVIGLYLLFKGRVGLKISLRDL-KPDWEWLKKIFRIGLPSSIEQ-S 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 247 AMATWFVFFIAI-ERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVCV 325
Cdd:cd13142 252 ARALGFTVMTALvAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKAALLIFLILVIGG 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 326 AVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTL-------VFYALYIL 398
Cdd:cd13142 332 VLAFLFAEPIVRVFINDPEVIKEGADFLRIVAPSFPFFGLFQVINGAFRGSGHTLTAMIISILRLwviriplAYLLAYVL 411
|
410
....*....|...
gi 949782817 399 -------WIGMVV 404
Cdd:cd13142 412 glgvtgiWIAMAI 424
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
4-379 |
4.02e-29 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 118.48 E-value: 4.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 4 NKEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPV 83
Cdd:cd13139 13 NRAIFLLAIPMVLEMVMESLFAVVDLYFVSRLGALAIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPEGAGFA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 84 MIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFafvnVMFRALYIGITR---TKVLTMNA 160
Cdd:cd13139 93 AVQAILLGVALSLILSILGYFFAEDILSLMGASPAVIAEGYGYTRIMFGGNGF----IMLLFLINGIFRgagDAAIAMRS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 161 VVMA-LVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSISCF 239
Cdd:cd13139 169 LWLAnGLNIILDPLFIFGLGPIPAMGVTGAAIATTIGRSIGVLYQLYHLFKGKGRIQIRRRHL-KLDWAIIKKIIKIAVG 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 240 TMIQYFLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFL 319
Cdd:cd13139 248 GILQFLIASSSWIFLVRIIAEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQPDRAEKSVWRAGKYNMV 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 320 IMVVCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNT 379
Cdd:cd13139 328 FLGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEALRIISLGYIFYGYGMVLSQAFNGAGDT 387
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
3-404 |
5.88e-27 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 111.88 E-value: 5.88e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 3 TNKEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGE-VELGASAMGGLFYICVFTIaFGF-SVGSQILIARRNGEGRYKDV 80
Cdd:cd13136 1 LHREILALALPAILSNITVPLLGLVDTAVVGHLGSaAYLGAVALGTTIFNTLFWL-FGFlRMGTTGLVAQALGAGDREEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 81 GPVMIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNA 160
Cdd:cd13136 80 IALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 161 VVMALVNVLLDYILIFGkFGmpeMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHwQKIDFSLLGKILSISCFT 240
Cdd:cd13136 160 IVGNVVNIVLDPLFVFG-LG---WGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLSR-RLPSKAALKRLFKLNRDI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 241 MIQY--FLAMATWFVFFIAieRLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSF 318
Cdd:cd13136 235 FIRTlaLLAAFLFFTALAA--RLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 319 LIMVVCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYA---- 394
Cdd:cd13136 313 GLGVLLALLFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVSLAVFLpllf 392
|
410
....*....|....*..
gi 949782817 395 -------LYILWIGMVV 404
Cdd:cd13136 393 llvplwgNHGLWLALIL 409
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
7-346 |
4.88e-23 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 100.75 E-value: 4.88e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 7 IWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQ 86
Cdd:cd13145 11 IRKLAIPASVGFFFNTMFNVVDTFFAGKISTEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRKARRYAAQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 87 GGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALV 166
Cdd:cd13145 91 GLSFGIILAILLTVIGLFAAPPLFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKSYRNFLIIGFFL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 167 NVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASlAFFLIYTYAKVDFKKFGLNHWQKIDFSLLGKILSISCFTMIQYFL 246
Cdd:cd13145 171 NIILDPLFIFGGGGIPAMGVSGIALATIISQFIG-MFYLLYKVRKSGIISGCRLRDFIPRLDVYKEILKQGFPASLNMMT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 247 AMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVCVA 326
Cdd:cd13145 250 IGLGIFVITYFVGQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKYDRVRETYKKALKYGFVIMVVATV 329
|
330 340
....*....|....*....|
gi 949782817 327 VVVLFPHAMLSVYTNEPALL 346
Cdd:cd13145 330 FLLFFAEPLMSLFTNDPAVI 349
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
4-385 |
5.69e-23 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 100.38 E-value: 5.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 4 NKEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPV 83
Cdd:cd13144 7 LRLLLTMSIPAMISMLFQALYNIVDSIFVARLGENALTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANKA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 84 MIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVM 163
Cdd:cd13144 87 ANNGLLLALLSYLLFLLLGLFGVKPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIAQLIG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 164 ALVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSISCFTMIQ 243
Cdd:cd13144 167 AIINIILDPILIFGLFGFPAMGIAGAAIATVIGQILAMFLAFFFLLRKNKDVQPDLRLF-RPSLRIIKEIYAVGLPSIIM 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 244 yfLAMATWFVFFIAIERLGQRELAIAniVRSIYIVM----LIPVQALSTTTNSLVSNLIGAGGITHVMRLIwRIAQM-SF 318
Cdd:cd13144 246 --QAISSVMVFGLNKILAGFGPTAVA--VFGIYFKLqsfvFMPVFGLNNGLIPIVAYNYGAGNKDRIREAI-KYAILiAV 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949782817 319 LIMVVCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALIL 385
Cdd:cd13144 321 VIMLAGGLLFQLFPDQLLGLFNASEEMLAIGVPALRIISLSFLFAALSIILSGLFQALGRGVYSLII 387
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
5-379 |
1.08e-22 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 99.52 E-value: 1.08e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVM 84
Cdd:cd13140 5 KTLLRLALPIMGTSFIQMAYNLTDMFWVGRLGSDAVAAVGTAGFFVWLAYALALLSKIGAQVKVSQSIGAKDEKEARKYA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 85 IQGGTFLLGLAMLMFGLTHLLAPSIVRLL-ISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVM 163
Cdd:cd13140 85 RNALQLNLLLGILYGLLLLLFAKPLIGFFnLGDAEVISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTPFIINAIG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 164 ALVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYaKVDFKKFGLNHWQKIDFSLLGKILSI------- 236
Cdd:cd13140 165 LVLNIILDPLLIFGFGPFPALGVAGAALATVLAQAIVFLLFLYALK-KKKGLFLKIRILKRPDRKYIKEILKLglpvalq 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 237 -SCFTMIQYFLA--MATWFVFFIAIERLGQRELAIANIVrsiyivmlipVQALSTTTNSLVSNLIGAGGITHVMRLIWRI 313
Cdd:cd13140 244 sILFALISMILAriIASFGPVAIAAQKVGSQIESISWMT----------AEGFSTALAAFVGQNYGAGKYDRIRKGYKTA 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949782817 314 AQMSFLIMVVCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNT 379
Cdd:cd13140 314 LKIASAIGLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRILGFSQLFMCLEITTTGAFNGLGRT 379
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
13-236 |
2.48e-21 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 95.65 E-value: 2.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 13 PIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGTFLL 92
Cdd:PRK01766 20 PILLAQVAQTAMGFVDTVMAGGVSATDLAAVAIGTSIWLPVILFGHGLLLALTPIVAQLNGAGRRERIAHQVRQGLWLAL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 93 GLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVlTMNAVVMAL-VNVLLD 171
Cdd:PRK01766 100 FLSVLIMLVLYNAVPPILNMMNLEPEVADIAVGYLHALLWGIPAYLLYQVLRSFIDGLGKTKP-TMVIGFLGLlINIPLN 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949782817 172 YILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGL-NHWQKIDFSLLGKILSI 236
Cdd:PRK01766 179 YIFIYGKFGFPELGGVGCGVATAIVYWVMFLAMLIYIKRARRFRDFRLfKGLYKPDWAVIKRLLKL 244
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
10-401 |
9.51e-21 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 93.91 E-value: 9.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 10 VSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGT 89
Cdd:cd13149 14 LTLPMIFGILAMLIFNLTDTFFVGKLGTKELAAISFTFPVVLFLNSLTIGLGIGASAVISRAIGAGDRNKAKRLATDSLI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 90 FLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVNVL 169
Cdd:cd13149 94 LSLLLSVIVSLLGLFTIPPLFSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRPSLVMLGAALVNVI 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 170 LDYILIFGKFGMPEMGIKGAAVASVMAEAASLA---FFLIYTYAKVDFKKFGLnhwqKIDFSLLGKILSI---SCFTMIQ 243
Cdd:cd13149 174 LDPILIFGFGPIPGMGIAGAAIATVISRALGLGaalYFLHYHHRLIDFSEPSL----KALFRSWKDILSIgipAALSNIL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 244 YFLAMAtwfVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHV---MRLIWRIAQMSFLI 320
Cdd:cd13149 250 TPLSAA---FITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVqegLKISLKFSLIYGAI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 321 MvvcVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYILWI 400
Cdd:cd13149 327 L---GIVLALFAGWLASLFSAEPEVIELITLYLLIVPIGYGGLGILIITSASFNALGKPLYSLGLNLIRVFLLYIPLAYV 403
|
.
gi 949782817 401 G 401
Cdd:cd13149 404 G 404
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
5-400 |
3.67e-20 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 92.38 E-value: 3.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVEL-GASAMGGLFYIcVFTIAFGFSVGSQILIARRNGEGRYKDVGPV 83
Cdd:cd13141 11 KHIISMALPIAIGMIIQTLYFLVDLYFVGQLGDAALaGVSLAGNVMFF-VMALTQVLNVGTAALVSHAVGRKDQGEANAV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 84 MIQGGTF--LLGLAMLMFGLthLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAV 161
Cdd:cd13141 90 FNQSLLLaaVLGLVVLVLGY--LFGRLYLETLAADAATVEAATTYLYWFIPSLALQFILTVLGAALRGTGIVKPFMVIQI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 162 VMALVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNHWqKIDFSLLGKILSI---SC 238
Cdd:cd13141 168 LAVLLNIILAPILITGWGTGRALGVAGAGLASSISVAIAVVLLLYYFLRLEKYLRLDLALW-RPDLPTWKRLLKIglpSG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 239 FTMIQYFLAMAtwfVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSF 318
Cdd:cd13141 247 GEFLLTFVYMA---VIYWALRPFGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRETFRITAILTT 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 319 LIMVVCVAVVVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYIL 398
Cdd:cd13141 324 ALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRYVSWNFVAAGLVFTCSGMFQALGNTWPSLLSSASRLLTFALPVI 403
|
..
gi 949782817 399 WI 400
Cdd:cd13141 404 WL 405
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-404 |
4.44e-17 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 82.83 E-value: 4.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 11 SYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGL---FYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQG 87
Cdd:cd13146 14 ALPILIGQLFQLLYNITDTIWISMIDPSDPALVGGIGLvfpLGMIFLALGNGIQVGVSSLLARAIGAQRAKELDQAADSG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 88 GTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVN 167
Cdd:cd13146 94 LALALLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRTKYMMMAMLIGTVVN 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 168 VLLDYILIFGKfgmpEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNhWQKIDFSLLGKILSISCFTMIQYFLA 247
Cdd:cd13146 174 IVLDPILIFVF----DMGVKGAALATVLAQAISLLYLLYVFLIGKSNVTIHIK-LSNISSSVIVEILRVGLPQMLLQLIS 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 248 MATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVCVAV 327
Cdd:cd13146 249 SISFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAVILGIVVVLVLVLG 328
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949782817 328 VVLFPHAMLSVYTNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVFYALYILWIGMVV 404
Cdd:cd13146 329 YVLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFFQAIGKAWPSLLLTLIRHVFLSVPVVYLLAYV 405
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
5-363 |
8.02e-17 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 82.24 E-value: 8.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFY-ICVFTIAFGFSVGSQILIARRNGEGRYKDVGpV 83
Cdd:cd13132 3 KKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLELAAASLASSFAnVTGFSILLGLASALDTLCGQAFGAKNYKLVG-V 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 84 MIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVM 163
Cdd:cd13132 82 YLQRALVILLLCCVPISLLWLNTEPILLLLGQDPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLVYISLVA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 164 ALVNVLLDYILIFgkfgMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKfGLNHWQKIDFSLLGKI--LSISCFTM 241
Cdd:cd13132 162 LLLNILLNYLLVF----VLGLGFIGAALATSISYWLIVVLLLLYIFFSKGHKA-TWGGFSREAFRGWGPFlkLAIPSALM 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 242 IqyflaMATWFVF----FIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVmRLIWRIA-QM 316
Cdd:cd13132 237 L-----CLEWWAFeilvLLAGLLPGTVALAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRA-KLAAIVAlIL 310
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 949782817 317 SFLIMVVCVAVVVLFPHAMLSVYTNEPAlLVESVPSLYVIAGAMIIA 363
Cdd:cd13132 311 SLVIGVVVAILLLVLRDVWAYLFTSDEE-VIALVADLLPILALFQIF 356
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
13-173 |
1.82e-16 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 76.45 E-value: 1.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 13 PIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGTFLL 92
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 93 GLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVNVLLDY 172
Cdd:pfam01554 81 LLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLNY 160
|
.
gi 949782817 173 I 173
Cdd:pfam01554 161 L 161
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-346 |
4.32e-15 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 76.93 E-value: 4.32e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 11 SYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGfSVGSQI--LIARRNGEGRYKDVGPVMIQGG 88
Cdd:cd13148 18 ALPNILALLVQTLVGLAETYFVGQLGTDALAGVALVFPLLMLTQMMSNG-AMGGGVssAIARALGAGDRERAEALVWHAL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 89 TFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVNV 168
Cdd:cd13148 97 VIALAGGLVFSLLFLLFGPALYRLLGGRGEALDAALAYSNVLFSGAILIWLVNLLAAALRGTGNMRVPALVTLVGAVVQI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 169 LLDYILIFGKFGMPEMGIKGAAVASVMAEAASLAFFLIY-----TYAKVDFKKFglnhwqKIDFSLLGKILSISCFTMIQ 243
Cdd:cd13148 177 PLSPGLILGWGPLPRLGVAGAAVAAVLYYALAALVLLRYlasgrSRLRLRLRAL------RLERRLFRDILRVGLLAALS 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 244 YFLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVV 323
Cdd:cd13148 251 PLQTNLTVLLLTGLVGRFGTAALAGYGIGSRLEFLLIPLVFGLGAAMTAMVGMNIGAGQIARARRIAWTGALMAAVLAGA 330
|
330 340
....*....|....*....|...
gi 949782817 324 CVAVVVLFPHAMLSVYTNEPALL 346
Cdd:cd13148 331 IGLVLALFPELWLGLFTHDPAVL 353
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
5-300 |
7.32e-11 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 63.71 E-value: 7.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVM 84
Cdd:cd13147 9 KAIIKLSIPMIIAMLLQTLYNLVDAIWVAGLGADALAAIGFVFPLFMIIIGLGNGLGAGASSAISRRIGAKDKEGADNAA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 85 IQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIfDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMA 164
Cdd:cd13147 89 VHSILLGLIISIILTIVLLPFLEPILVLMGAGEVL-DLAVDYGRIIFLGSIFLIFNNVAYGILRGEGDTKRAMYAMVAGS 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 165 LVNVLLDYILIFgkfgMPEMGIKGAAVASVMAEAASLAFFLIY------TYAKVDFKKFglnhwqKIDFSLLGKILSISC 238
Cdd:cd13147 168 ILNIILDPIFIY----TLGLGIAGAAWATVISMLISSLVLLYWffvkkdTYVSLSLKNF------KFDKKIVKDILKVGI 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949782817 239 FTMIQYF-LAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGA 300
Cdd:cd13147 238 PASLEQLiMSVLMIILNLILVIVAGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGA 300
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
7-205 |
1.53e-07 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 53.03 E-value: 1.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 7 IWNVSYPIFLGLLAQNIINVTDTAFLGR-VGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMI 85
Cdd:COG2244 175 VLKYSLPLLLSGLLGLLLTNLDRLLLGAlLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYR 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 86 QGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDsiFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMAL 165
Cdd:COG2244 255 KALRLLLLLGLPLALGLALLAPPLLSLLFGPE--YAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAV 332
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 949782817 166 VNVLLDYILIfgkfgmPEMGIKGAAVASVMAEAASLAFFL 205
Cdd:COG2244 333 LNLVLNLLLI------PRYGLVGAAIATLLSYLVLLLLLL 366
|
|
| vmrA |
PRK09575 |
MATE family efflux transporter; |
62-349 |
5.81e-07 |
|
MATE family efflux transporter;
Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 51.53 E-value: 5.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 62 VGSQILIARRNGEGRYKDVGPVMIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNV 141
Cdd:PRK09575 70 MGTGSLLSIKRGEGDLEKAKRILTTGLLLLLLLGPIVSVILFLFADDFLRAQGAEGRTLELALQYIQVLIWGCLFTLGAI 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 142 MFRALYIGITRTKVLTMNAVVMALVNVLLDYILIfgkfGMPEMGIKGAAVASVMAEAASLAFFLIYTYAKVDFKKFGLNH 221
Cdd:PRK09575 150 ALPFLLRNDESPNLATGLMVIGALINIVLDYLFI----GWLDWGLTGAAIATALAQLVVTVLGLGYFFSSRANIRLTLKE 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 222 wQKIDFSLLGKILSI--SCFTMIQYflamaTWFVFFIA----IERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVS 295
Cdd:PRK09575 226 -LRFNWSLAPKIVLLgsSSFFMYLY-----GSFVVALHnrlfMEYGSALTVGAYAIVGYLMVLYYLVAEGIAEGMQPPVS 299
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 949782817 296 NLIGAGGITHVMRLIWRIAQMSFLIMVVCVAVVVLFPHAMLSVYTNEPALLVES 349
Cdd:PRK09575 300 YYFGARQYDNIKKLLKLAMKVTVLAGIAWVLLLNLFPETMIALFNSGDSELIAE 353
|
|
| PRK00187 |
PRK00187 |
NorM family multidrug efflux MATE transporter; |
13-357 |
7.08e-06 |
|
NorM family multidrug efflux MATE transporter;
Pssm-ID: 166843 [Multi-domain] Cd Length: 464 Bit Score: 48.20 E-value: 7.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 13 PIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVMIQGGTFLL 92
Cdd:PRK00187 18 PLIASQLAHMLMVFTDTLMMGRLGPEALAGGGLGAASYSFVSIFCVGVIAAVGTLVAIRHGAGDIEGATRLAQAGLWLAW 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 93 GLAMLMFGLTHLLAPsIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVNVLLDY 172
Cdd:PRK00187 98 LLALVAALLLWNLKP-LLLLFGQAPQNVDAAMQFLHLLPFALPGYLSFMALRGFTSALGRAGPVMVISLAGAVANLLLNY 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 173 ILIFGKFGMPEMGIKG-----AAVASVMAEAASLAFFLIYTYAKVDFKKfGLNhwqKIDFSLLGKILSISCFTMIQYFLA 247
Cdd:PRK00187 177 ALIEGWFGLPKLGLMGiglvtALVSNGMALALALYIRRHPAYAAYPLRK-GLS---RPSRAALRELWRLGLPIGGTYAVE 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 248 MATWFVFFIAIERLGQRELAIANI-VRSIYIVMLIPVqALSTTTNSLVSNLIGAGGITHVmRLIWRIAqMSF--LIMVVC 324
Cdd:PRK00187 253 VGLFTFAALCMGALGSTQLAAHQIaLQIVSVAFMVPV-GLSYAVTMRVGQHYGAGRLLEA-RRAGRVG-IGFgaVVMLLF 329
|
330 340 350
....*....|....*....|....*....|....*..
gi 949782817 325 VAVVVLFPHAMLSVYT--NEPA--LLVESVPSLYVIA 357
Cdd:PRK00187 330 AGLFWLLPEAIIGLFLdrNDPAfaEIVQLAVSLLAVA 366
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
5-209 |
1.18e-05 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 47.15 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLG-RVGEVELG--ASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVg 81
Cdd:cd13128 206 KELLRFSIPLALSGIFSLIYTRIDTIMLGyFLGDAAVGiyNAAYRIAELLLFIPSAISTALFPRISELYKNDKDELKKL- 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 82 pvMIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMefLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAV 161
Cdd:cd13128 285 --LKKSFKYLFLISLPIAIGLFLFAEPIITLLFGEEYLPAALV--LQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILL 360
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 949782817 162 VMALVNVLLDYILIfgkfgmPEMGIKGAAVASVMAEAASLAFFLIYTY 209
Cdd:cd13128 361 IGALLNVILNLLLI------PKYGIIGAAIATLISEFIIFILLLYLLK 402
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
260-392 |
2.12e-05 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 44.48 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 260 RLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQMSFLIMVVCVAVVVLFPHAMLSVY 339
Cdd:pfam01554 22 HLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGLLLSLPIALLVLLFSEPILSLF 101
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 949782817 340 TNEPALLVESVPSLYVIAGAMIIASVANIYFNAISGTGNTQAALILEMGTLVF 392
Cdd:pfam01554 102 GQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLL 154
|
|
| PRK10189 |
PRK10189 |
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
5-343 |
6.45e-05 |
|
EmmdR/YeeO family multidrug/toxin efflux MATE transporter;
Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 45.11 E-value: 6.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 5 KEIWNVSYPIFLGLLAQNIINVTDTAFLGRVGEVELGASAMGGLFYICVFTIAFGFSVGSQILIARRNGEGRYKDVGPVM 84
Cdd:PRK10189 29 REITPLAVPIFIENLCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 85 IQGGTFLLGLAMLMFGLTHLLAPSIVRLLISS--DSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVLTMNAVV 162
Cdd:PRK10189 109 RQSLVIMTLFAVLLAVLIHFFGEQIIDLVAGDatPEVKALALTYLELTVWSYPAAAITLIGSGALRGAGNTKIPLLINGG 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 163 MALVNVLLDYILIFGKFGMPEMGIKGAAVASVMAEAASlAFFLIYTYA-------KVDFKKFglnhWQKIDFSLLGKILS 235
Cdd:PRK10189 189 MNILNIIISSILIYGLFSWQGLGFVGAGLGLTISRYIG-AVAIIWVLMigfnpalRISLKSY----FKPLNFAIIWEVMG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 236 ISCFTMIQYFLAMATWFVFFIAIERLGQRELAIANIVRSIYIVMLIPVQALSTTTNSLVSNLIGAGGITHVMRLIWRIAQ 315
Cdd:PRK10189 264 IGIPASIESVLFNGGKLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGTRLGKGQIAQAERQLRHVFW 343
|
330 340
....*....|....*....|....*...
gi 949782817 316 MSFLIMVVCVAVVVLFPHAMLSVYTNEP 343
Cdd:PRK10189 344 LSTLGLTAIAWLSAPFAGLLASFYTQDP 371
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
131-258 |
2.09e-04 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 41.40 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 131 IWGFFFAFVNVMFRALYIGITRTKVLTMNAVVMALVNVLLDYILIfgkfgmPEMGIKGAAVASVMAEAASLAFFLIYTYA 210
Cdd:pfam14667 6 ALSIIFLSLSTVLTSILQGLGRTKLALIALLIGALVKLILNLLLI------PLFGIVGAAIATVISLLVVALLNLYYLRR 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 949782817 211 KVDFKKFGLNHWQKIDFSLLGKILSISCFTMIQYFLAMATWFVFFIAI 258
Cdd:pfam14667 80 YLGLRLLLRRLLKPLLAALVMGIVVYLLLLLLGLLLGLALALLLAVLV 127
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
3-201 |
7.64e-03 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 38.57 E-value: 7.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 3 TNKEIWNVSYPIFLGLLAQNIINVTDTAFLGRV------GEVELGASAMGGLFYICVFtiafgFSVGSQILIARRNGEGR 76
Cdd:PRK10367 7 SDKALWRLALPMIFSNITVPLLGLVDTAVIGHLdspvylGGVAVGATATSFLFMLLLF-----LRMSTTGLTAQAFGAKN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949782817 77 YKDVGPVMIQGGTFLLGLAMLMFGLTHLLAPSIVRLLISSDSIFDATMEFLNWRIWGFFFAFVNVMFRALYIGITRTKVL 156
Cdd:PRK10367 82 PQALARALVQPLLLALGAGALIALLRTPLIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAP 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 949782817 157 TMNAVVMALVNVLLDYILIFGKfgmpEMGIKGAAVASVMAEAASL 201
Cdd:PRK10367 162 VILLVVGNILNIVLDLWLVMGL----HMNVQGAALATVIAEYATL 202
|
|
| |
