|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
6-553 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1033.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 6 TPHDVTALPAWQALVQHRQAMQDFSMREAFNADPQRFSQFTLSSCGLFLDYSKNLITSETRDLLVGLAKEVNLKAAIDAQ 85
Cdd:PRK00179 1 KNINLTQTPAWQALQAHADEIKDVHLRDLFAADPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 86 YAGEPVNSSEGRPALHTALRRPVGDKLSVNGVNIMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGP 165
Cdd:PRK00179 81 FAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 166 ELVSEALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAELYRHFI 245
Cdd:PRK00179 161 VMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVAKHFV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 246 AVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYTMDQHFLNAPFEANMPVLLGLLG 325
Cdd:PRK00179 241 AVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLALIG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 326 VWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPA 405
Cdd:PRK00179 321 VWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKLVPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 406 DFIVPIVSFNPVSDHHQWLYANCLSQSQALMLGKTRSEAEAELREKGLPEADVQKLAPHKVIPGNRPSNTLVVERISPRR 485
Cdd:PRK00179 401 DFIAPAQPHNPLGDHHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDRLTPFT 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 948126637 486 LGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEETLAEDASTQGLINYFRGRHR 553
Cdd:PRK00179 481 LGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
11-550 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 710.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 11 TALPAWQalvqhrqamqdfSMReafnadpqRFSQFTLSSCGLFLDYSKNLITSETRDLLVGLAKEvnlKAAIDAQYAGEP 90
Cdd:COG0166 2 TQTPAWQ------------HLR--------RFERFSLEAAGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEK 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 91 VNSSEGRPALHTALRRPVGdklsvnGVNIMPDVHKVLNQITDLVGRIHDGlwrgyteKPITDVVNIGIGGSFLGPELVSE 170
Cdd:COG0166 59 INPTEGRAVLHGALRLPEA------GEDVMPEVREELARIKAFAEKVRTG-------KRITDVVNIGIGGSDLGPRAVIE 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 171 ALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAelYRHFIAVSSN 250
Cdd:COG0166 126 ALKPYFRDGPRVHFVSNVDPDYLAELLAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGEDA--AKHFVAVTDN 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 251 NAAAVAFGIREE-NIFPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSGAYTMDQHFLNAPFEANMPVLLGLLGVWYG 329
Cdd:COG0166 204 AGALRAFGIDEGyNTFPFPDWVGGRYSVLSAVGLLPAAAIGI-DFEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYR 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 330 NFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPViwGGVGCNGQHAYHQLLHQGTQLIPADFIV 409
Cdd:COG0166 283 NFKGAETEAVLPYDQRLERFPAWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIA 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 410 PIVSFNPVSDhhqWLYANClsQSQALMLGKTRSEAEAELREKglpeadvqklAPHKVIPGNRPSNTLVVERISPRRLGAL 489
Cdd:COG0166 361 VAEPHHDIPD---LLLANL--QGLALLAGKTLDEVLALAAEA----------TPHALFPGNRPSNTILLPKLTPYTLGAL 425
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 948126637 490 VAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEEtlAEDASTQGLINYFRG 550
Cdd:COG0166 426 IALYEHAVFVQGVLWGINPFDQPGVELGKKLAFALLGKLGGEEA--AAGDSTEALLKRLRA 484
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
55-545 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 656.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 55 DYSKNLITSETRDLLVGLAKEVNLKAAIDAQYAGEPVNSSEGRPALHTALRRPVGDKLSVNGVNIMPDVHKVLNQITDLV 134
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 135 GRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELVSEALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSF 214
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 215 NTLETLKNAQAARAWYLAQGGSEAELYRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNF 294
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 295 KELLSGAYTMDQHFLNAPFEANMPVLLGLLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVST 374
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 375 DTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPIVSFNP-VSDHHQWLYANCLSQSQALMLGKTRSEAEAELRekgl 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPeNGDHHKILLSNFFAQTEALMVGKSPEEVRKELA---- 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 454 pEADVQKLAPHKVIPGNRPSNTLVVERISPRRLGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEE 533
Cdd:pfam00342 397 -AADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSNK 475
|
490
....*....|..
gi 948126637 534 TLAEDASTQGLI 545
Cdd:pfam00342 476 VSSHDSSTNGLI 487
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
335-524 |
3.88e-71 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 225.17 E-value: 3.88e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 335 QSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVstDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVP---- 410
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVkkpq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 411 --IVSFNPVSDHHQWLYANCLSQSQALMlgktrseaeaelrekglpeadvqklaphkvIPGNRPSNTLVVERISPRRLGA 488
Cdd:cd05016 79 ndVLDYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 948126637 489 LVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGV 524
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
6-553 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1033.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 6 TPHDVTALPAWQALVQHRQAMQDFSMREAFNADPQRFSQFTLSSCGLFLDYSKNLITSETRDLLVGLAKEVNLKAAIDAQ 85
Cdd:PRK00179 1 KNINLTQTPAWQALQAHADEIKDVHLRDLFAADPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 86 YAGEPVNSSEGRPALHTALRRPVGDKLSVNGVNIMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGP 165
Cdd:PRK00179 81 FAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 166 ELVSEALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAELYRHFI 245
Cdd:PRK00179 161 VMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVAKHFV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 246 AVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYTMDQHFLNAPFEANMPVLLGLLG 325
Cdd:PRK00179 241 AVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLALIG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 326 VWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPA 405
Cdd:PRK00179 321 VWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKLVPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 406 DFIVPIVSFNPVSDHHQWLYANCLSQSQALMLGKTRSEAEAELREKGLPEADVQKLAPHKVIPGNRPSNTLVVERISPRR 485
Cdd:PRK00179 401 DFIAPAQPHNPLGDHHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDRLTPFT 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 948126637 486 LGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEETLAEDASTQGLINYFRGRHR 553
Cdd:PRK00179 481 LGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
11-550 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 710.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 11 TALPAWQalvqhrqamqdfSMReafnadpqRFSQFTLSSCGLFLDYSKNLITSETRDLLVGLAKEvnlKAAIDAQYAGEP 90
Cdd:COG0166 2 TQTPAWQ------------HLR--------RFERFSLEAAGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEK 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 91 VNSSEGRPALHTALRRPVGdklsvnGVNIMPDVHKVLNQITDLVGRIHDGlwrgyteKPITDVVNIGIGGSFLGPELVSE 170
Cdd:COG0166 59 INPTEGRAVLHGALRLPEA------GEDVMPEVREELARIKAFAEKVRTG-------KRITDVVNIGIGGSDLGPRAVIE 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 171 ALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAelYRHFIAVSSN 250
Cdd:COG0166 126 ALKPYFRDGPRVHFVSNVDPDYLAELLAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGEDA--AKHFVAVTDN 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 251 NAAAVAFGIREE-NIFPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSGAYTMDQHFLNAPFEANMPVLLGLLGVWYG 329
Cdd:COG0166 204 AGALRAFGIDEGyNTFPFPDWVGGRYSVLSAVGLLPAAAIGI-DFEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYR 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 330 NFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPViwGGVGCNGQHAYHQLLHQGTQLIPADFIV 409
Cdd:COG0166 283 NFKGAETEAVLPYDQRLERFPAWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIA 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 410 PIVSFNPVSDhhqWLYANClsQSQALMLGKTRSEAEAELREKglpeadvqklAPHKVIPGNRPSNTLVVERISPRRLGAL 489
Cdd:COG0166 361 VAEPHHDIPD---LLLANL--QGLALLAGKTLDEVLALAAEA----------TPHALFPGNRPSNTILLPKLTPYTLGAL 425
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 948126637 490 VAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEEtlAEDASTQGLINYFRG 550
Cdd:COG0166 426 IALYEHAVFVQGVLWGINPFDQPGVELGKKLAFALLGKLGGEEA--AAGDSTEALLKRLRA 484
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
55-545 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 656.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 55 DYSKNLITSETRDLLVGLAKEVNLKAAIDAQYAGEPVNSSEGRPALHTALRRPVGDKLSVNGVNIMPDVHKVLNQITDLV 134
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 135 GRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELVSEALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSF 214
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 215 NTLETLKNAQAARAWYLAQGGSEAELYRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNF 294
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 295 KELLSGAYTMDQHFLNAPFEANMPVLLGLLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVST 374
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 375 DTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPIVSFNP-VSDHHQWLYANCLSQSQALMLGKTRSEAEAELRekgl 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPeNGDHHKILLSNFFAQTEALMVGKSPEEVRKELA---- 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 454 pEADVQKLAPHKVIPGNRPSNTLVVERISPRRLGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEE 533
Cdd:pfam00342 397 -AADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSNK 475
|
490
....*....|..
gi 948126637 534 TLAEDASTQGLI 545
Cdd:pfam00342 476 VSSHDSSTNGLI 487
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
9-548 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 588.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 9 DVTALPAWQALVQHRQAMQDFSMREAFNaDPQRFSQFTLSSCGLFLDYSKNLITSETRDLLVGLAKEVNLKAAIDAQYAG 88
Cdd:PLN02649 7 LISDTPAWKRLVAHVYQIKKTHLRELLN-DAERCQSMIAEFDGIYLDYSRQRVTDETMELLFPLAEAANLFEKIEAMFSG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 89 EPVNSSEGRPALHTALRRPVGDKLSVNGVNIMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELV 168
Cdd:PLN02649 86 EIINSTEDRAVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIGGSFLGPLFV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 169 SEALLSY-----AHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAeLYRH 243
Cdd:PLN02649 166 HEALATDpealkSAKGRKLRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRDALGGLA-VAKH 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 244 FIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIG-LPIALAIGMSNFKELLSGAYTMDQHFLNAPFEANMPVLLG 322
Cdd:PLN02649 245 MVAVSTNLLLVNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRTAPLKENIPVLLG 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 323 LLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGtQL 402
Cdd:PLN02649 325 LLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQHSFYQLIHQG-RN 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 403 IPADFIVPIVSFNPVSD-------HHQWLYANCLSQSQALMLGKTRSEAEAElrekGLPEAdvqkLAPHKVIPGNRPSNT 475
Cdd:PLN02649 404 IPCDFIGVVRSQQPVHLwlgegvsNHDELMSNFFAQPDALAYGKTPEQLRAE----GVPEE----LIPHKVFAGNRPSLS 475
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 948126637 476 LVVERISPRRLGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEETLAE----DASTQGLINYF 548
Cdd:PLN02649 476 ILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNEARTKGEPvegfNSSTTALLNHY 552
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
9-549 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 543.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 9 DVTALPAWQALVQHRQAMQDFSMREAFNaDPQRFSQFTLSSCGLFLDYSKNLITSETRDLLVGLAKEVNLKAAIDAQYAG 88
Cdd:PTZ00430 2 DLESLKSYKNLLSLAEKLKKVHLRDLLK-DEERNKSLIKEFKGVTLDLSRQRLDEETLKLLIELAEEAKLKEKIKDMFNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 89 EPVNSSEGRPALHTALRRPVGDKLSVNGVNIMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELV 168
Cdd:PTZ00430 81 EKINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLDRIKKFSDKIRSGEILGSTGKKLKNVICIGIGGSYLGTEFV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 169 SEALLSY-----AHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAELYRH 243
Cdd:PTZ00430 161 YEALRTYgeareASKGRKLRFLANVDPIDVRRATEGLDPEETLVVIISKTFTTAETMLNAKTVRQWLLDNIKSKEALSKH 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 244 FIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIG-LPIALAIGMSNFKELLSGAYTMDQHFLNAPFEANMPVLLG 322
Cdd:PTZ00430 241 LCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGiLPLSIQFGYDIVQQFLNGCHDMDEHFRTAPLEENLPVLLG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 323 LLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGtQL 402
Cdd:PTZ00430 321 LTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNGKSVTLDGNTLDYNTGEIYFGEPGTNGQHSFYQLLHQG-RV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 403 IPADFI------VPIVSFNPVSDHHQWLYANCLSQSQALMLGKTRSEAEAElrekGLPEadvqKLAPHKVIPGNRPSNTL 476
Cdd:PTZ00430 400 VPSEFIgfaksqNPIKLLGEPVSNHDELMSNFFAQPDALAFGKTYEELEKE----GVPE----ELIPHKVFPGNRPSLLL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 477 VVERISPRRLGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGV----YNRLTGAEETLAED---ASTQGLINYFR 549
Cdd:PTZ00430 472 LFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVELGKVLAKDVrnlfKDNRSNSSPHAKESkfnGSTKRLLSYYL 551
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
1-548 |
1.40e-132 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 396.69 E-value: 1.40e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 1 MAYYRtphDVTALPAWQALVQHRQAMQDFSMREAFNADpqRFSQFTLSSCGLFLDYSKNLITSETRDLLVGLAKEVNLKA 80
Cdd:PRK14095 1 MMNYK---NFLDLESFKILQELAPEPLDLTLPGVLSEE--RIKKYSLSGEGFTYNYATERVDDRILAALQNLADEAELIE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 81 AIDAQYAGEPVNS-----SEGRPALHTALRRPVGDK-LSVNGVNIMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVV 154
Cdd:PRK14095 76 KMKAMQNGAVINRiegfpSENRPVLHTATRGQVGDSvLTDEAEDMAEFSKRELERLAEFLKKVRSGEIKNSNGKKFTTVV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 155 NIGIGGSFLGPELVSEALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQG 234
Cdd:PRK14095 156 QIGIGGSDLGPKALYLALKNYAKKDKRVHFISNVDPDDAAEVLSEIDLAKTLFIVVSKSGTTLETAANEEFVRDALKKAG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 235 GSEAelyRHFIAVSSNNAAaVAFGIREENIFPMWDWVGGRYSLWSAIGLP-IALAIGMSNFKELLSGAYTMDQHFLNAPF 313
Cdd:PRK14095 236 LDYK---KHFIAVTSEGSP-MDDESGYLEVFHMWDSIGGRFSSTSMVGGVvLGFAFGFEVFKEFLKGAAAMDKAALNPNI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 314 EANMPVLLGLLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYH 393
Cdd:PRK14095 312 RENLPLLAALIGIWNRNFLGYPTTAVIPYSQALERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGTNGQHSFF 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 394 QLLHQGTQLIPADFI--------VPIVSFNPVSdhHQWLYANCLSQSQALMLGKTRSEaeaelrekglpeadvqklaPHK 465
Cdd:PRK14095 392 QLLHQGTDIVPVEFIgfkesqlgQDIVIQGSTS--QQKLFANLIAQIIALACGKENTN-------------------PNK 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 466 VIPGNRPSNTLVVERISPRRLGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLTGAEEtlAEDASTQGLI 545
Cdd:PRK14095 451 NFKGNRPSSLLVAKQLTPYTLGALLAHYENKVMFQGFCWNINSFDQEGVQLGKVLANQILGIMKGEAP--GEFPEADGLL 528
|
...
gi 948126637 546 NYF 548
Cdd:PRK14095 529 KLF 531
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
335-524 |
3.88e-71 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 225.17 E-value: 3.88e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 335 QSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVstDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVP---- 410
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVkkpq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 411 --IVSFNPVSDHHQWLYANCLSQSQALMlgktrseaeaelrekglpeadvqklaphkvIPGNRPSNTLVVERISPRRLGA 488
Cdd:cd05016 79 ndVLDYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 948126637 489 LVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGV 524
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
124-288 |
4.47e-68 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 216.62 E-value: 4.47e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 124 HKVLNQITDLVGRIHDGlwrgyteKPITDVVNIGIGGSFLGPELVSEALLSYAHKGVRCHYLANIDGSEFHELTMKLRAE 203
Cdd:cd05015 1 RAELERIKEFAEKVRSG-------KKITDVVVIGIGGSDLGPRAVYEALKPYFKGGLRLHFVSNVDPDDLAELLKKLDPE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 204 TTLFIVSSKSFNTLETLKNAQAARAWYLAQGGseAELYRHFIAVSSNNAAAVA-FGIREENIFPMWDWVGGRYS-LWSAI 281
Cdd:cd05015 74 TTLFIVISKSGTTLETLANARLAREWLEEAGG--DDLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWVGGRFSvLSSVG 151
|
....*..
gi 948126637 282 GLPIALA 288
Cdd:cd05015 152 GLPLALA 158
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
80-540 |
8.76e-56 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 195.87 E-value: 8.76e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 80 AAIDAQYAGEPVNSSEGRPALHTALRRPvgdKLSVNGvNIMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIG 159
Cdd:PRK14096 48 AAMAALEAGAIANPDEGRMVGHYWLRNP---ELAPTP-EIRAEITETLAQIEAFAAKVHSGTIKPPNGEKFTDVLWIGIG 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 160 GSFLGPELVSEALLSyAHKGVRCHYLANID----GSEFHELTMKLRaeTTLFIVSSKSFNTLETLKNAQAARAWYLAQGG 235
Cdd:PRK14096 124 GSALGPQFVAEALQP-NSDGLNIHFIDNTDpdgiDRVLAELGDRLA--TTLVVVISKSGGTPETRNGMLEAKAAYEAAGL 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 236 SEAelyRHFIAVSSNNA--AAVAfgiREEN---IFPMWDWVGGRYSLWSAIGL-PIALaIGmSNFKELLSGAYTMDQHFL 309
Cdd:PRK14096 201 DFA---SHAVAITMKGSklDQLA---QSEGwlaRFPMWDWVGGRTSETSAVGLlPAAL-QG-IDIRAFLAGAKQMDEATR 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 310 NAPFEANMPVLLGLlgVWY--GNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVstDTGPVIWGGVGCN 387
Cdd:PRK14096 273 VPDLKNNPAALLAL--AWYyaGDGKGKKDMVVLPYKDRLLLFSRYLQQLVMESLGKELDLDGNVV--HQGIAVYGNKGST 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 388 GQHAYHQLLHQGtqlIPADFivpiVSFNPVSDHHQWLYANCLSQS------QALMLGkTRSeaeaELREKGlpeadvqkl 461
Cdd:PRK14096 349 DQHAYVQQLRDG---VDNFF----VTFIEVLEDRQGSSIEVEPGVtsgdylSGFLQG-TRQ----ALYENG--------- 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 462 aphkvipgnRPSNTLVVERISPRRLGALVAMYEHKV-FVQSVVwGINAFDQWGVELGKELGKGVYNRLTGAEETLAEDAS 540
Cdd:PRK14096 408 ---------RQSITITIPEVNPRTLGALIALFERAVgLYASLV-NINAYHQPGVEAGKKAAAAILDLQKKVEELLKEDGG 477
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
151-518 |
7.83e-32 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 127.80 E-value: 7.83e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 151 TDVVNIGIGGSFLGPELVSEAL--LSYAH------KGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKN 222
Cdd:PRK00973 72 DNVVVLGIGGSALGNLALHYALnpLNWNElskeerNGPRVFVLDNVDPEKTASILDVIDLEKTLFNVISKSGNTAETLAN 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 223 AQAARAWYLAQGGSEAElyrHFIAVSSNNAAAVAFGIREENI--FPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSG 300
Cdd:PRK00973 152 YLIIRGILEKLGLDPKK---HLVFTTDPEKGKLKKIAEKEGYrtLEIPENVGGRFSVLTPVGLAPAAALGI-DIEELLEG 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 301 AYTMDQHFLNAPFEANMPVLLGLLGVWYGNFwGAQSHAILPYDHYLRNITKHLQQLDMESNGKsvRQDG-TPVstdtgpv 379
Cdd:PRK00973 228 AKEMDKICEKEDIFKNPALLNALIHYLYYNR-GKNISVMMPYSERLKYFGDWYRQLWAESLGK--KGVGqTPV------- 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 380 iwGGVGCNGQHAYHQLLHQGtqliPADFIVPIVSFNP-------VSDHHQWLYANCLSqsqalmlGKTRSE---AEAELR 449
Cdd:PRK00973 298 --KALGATDQHSQLQLYMEG----PKDKIITFLKVEKyrrdveiPYEYEDIEELSYLG-------GHKLSElinSEQKGT 364
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 948126637 450 EKGLPEAdvqklaphkvipgNRPSNTLVVERISPRRLGALVAMYEHKVFVQSVVWGINAFDQWGVELGK 518
Cdd:PRK00973 365 EIALTEN-------------GRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGVELGK 420
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
150-518 |
4.02e-24 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 104.63 E-value: 4.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 150 ITDVVNIGIGGSFLGPELVSEALLSYAHKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAW 229
Cdd:PRK03868 58 IKNIVVIGIGGSSLGVKAIYSFLKNEKNNKKELHFLENTDPISINKTLSKINLENTLFIVISKSGTTIETISIFKYLLSH 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 230 YlaqgGSEAELYRHFIAV----SSNNAAAVAFGIREENIFPMwdwVGGRYSLWSAIGLpIALAIGMSNFKELLSGAYTMD 305
Cdd:PRK03868 138 F----KLDQELKKNFLFItdpdSKLEQFAKENNIKCFNIPKN---VGGRFSVLSAVGI-VPLALCGYDIKALLEGAKACK 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 306 QHFLN---------APFeanmpvllgllgvwYGNFWGAQS-HAILPYDHYLRNITKHLQQLDMESNGK----SVRQDGTP 371
Cdd:PRK03868 210 DSFFEqkedhilkkAYF--------------YATHKNAYNiNVLFSYSDALKGFNDWYVQLWGESLGKkqgyKTRVGLTP 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 372 VstdtgpviwGGVGCNGQHAYHQLLHQGTQ------LIPADF----IVPIVSFNPVSDHHqwlYANCLSQSQALmlgktR 441
Cdd:PRK03868 276 I---------GLIGSRDQHSFLQLIMEGPRdktvtfIKIKDFqnapKIPNISLKGLESLD---FVNGVSFNELI-----N 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 442 SEAEAELrekglpeadvqklapHKVIPGNRPSNTLVVERISPRRLGALVAMYEhkvFVQSVV---WGINAFDQWGVELGK 518
Cdd:PRK03868 339 AQCDATM---------------EALIAEDIPVDVITLEKLDEFSIGYLIYYYE---LLTSAVgkmLGINTYDQPGVEVGK 400
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
150-304 |
2.91e-15 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 79.24 E-value: 2.91e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 150 ITDVVNIGIGGSFLGPELVSEallSYAHKG--VRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETlkNAQAAR 227
Cdd:PRK09533 455 FTDAVVLGMGGSSLGPEVLAE---TFGQRDgfPKLHVLDSTDPAQVRALEAAVDLARTLFIVSSKSGGTLEP--NIFKDY 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 228 AWYLAQGGSEAELYRHFIAV----SSNNAAAVAFGIREenIFPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSGAYT 303
Cdd:PRK09533 530 FFARVKEVLGAKAGRHFVAVtdpgSSLEKVAKEDGFRK--IFHGDPDIGGRYSVLSPFGLVPAAAAGI-DVRALLDSALA 606
|
.
gi 948126637 304 M 304
Cdd:PRK09533 607 M 607
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
151-316 |
2.66e-08 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 56.39 E-value: 2.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 151 TDVVNIGIGGSFLGPELVSEALLSYAH--------KGVRCHYLAN-IDGSEFHELTMKLRAETTLFIVSSKSFNTLETLK 221
Cdd:PRK14097 74 DVLVVIGIGGSYLGARAAIEFLNHSFYnllpkeqrKAPQIIFAGNsISSTYLADLLEYLKDKDFSINVISKSGTTTEPAI 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 948126637 222 NAQAARAWYLAQGGseAELYRHFIAVSSNNAAAVAFGIREEN---IFPMWDWVGGRYSLWSAIGL-PIALAiGMsNFKEL 297
Cdd:PRK14097 154 AFRIFKELLEKKYG--KEEAKKRIYATTDKAKGALKTLADAEgyeTFVIPDDVGGRFSVLTAVGLlPIAVA-GI-DIDAL 229
|
170
....*....|....*....
gi 948126637 298 LSGAYTMDQHFLNAPFEAN 316
Cdd:PRK14097 230 MKGAADARKDYSSSDLSEN 248
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|
| SIS_PGI_PMI_1 |
cd05017 |
The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the ... |
152-227 |
3.64e-03 |
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The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to fructose 6-phosphate, and mannose 6-phosphate to fructose 6-phosphate, respectively at an equal rate. This protein contains two SIS domains. This alignment is based on the first SIS domain.
Pssm-ID: 240148 [Multi-domain] Cd Length: 119 Bit Score: 37.63 E-value: 3.64e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 948126637 152 DVVNIGIGGSFLGPELVSEALLSYAHKGVRCHYLANIDGSefheltmklRAETTLFIVSSKSFNTLETLKNAQAAR 227
Cdd:cd05017 1 NIVILGMGGSGIGGDLLESLLLDEAKIPVYVVKDYTLPAF---------VDRKTLVIAVSYSGNTEETLSAVEQAK 67
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